acetylcysteine and mannitol

acetylcysteine has been researched along with mannitol in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.89)18.7374
1990's5 (13.16)18.2507
2000's17 (44.74)29.6817
2010's12 (31.58)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cervantes, A; Lankelma, J; Pinedo, HM; Schuurhuis, GJ1
Clark, EP; Stossel, TP; Weitberg, AB; Weitzman, SA1
Stossel, TP; Weitzman, SA1
Harrison, PM; Keays, R; Wendon, JA; Williams, R1
Bakker, LJ; de Graaf, L; Machiel de Vos, N; Nottet, HS; van Strijp, JA; Verhoef, J; Visser, MR1
Klein, U; Kretzschmar, M; Palutke, M; Schirrmeister, W1
Boussa, N; Dutertre-Catella, H; Ernouf, D; Legras, A1
Grossman, N; Halevy, S; Lubart, R; Reuveni, H; Schneid, N1
Hattori, S; Hattori, Y; Kasai, K; Sato, N1
Davidson, SD; Eshghi, M; Konno, S; Mallouh, C; Nowzari, FB; Tazaki, H1
Roumen, RM; Vader, HL; Van Den Wall Bake, AW; Wijnen, MH1
Chatterjee, M; Dwivedi, VK; Khandekar, K; Mathur, N; Prasad, S; Singh, S; Tandon, SK1
De Vriese, AS; Lameire, NH; Vanholder, R1
Lepor, NE1
Bohosiewicz, J; Byrka-Owczarek, K; Koszutski, T; Krasoń, M; Steplewska-Mazur, K; Wojtynek, G1
Kellum, J; Leblanc, M; Venkataraman, R3
Airoldi, F; Briguori, C; Colombo, A; Morici, N1
Chakrabarti, SK; Lemieux, N; M'Bemba-Meka, P1
Gouverneur, MC; Hoekstra, JB; Holleman, F; Kastelein, JJ; Levi, M; Meijers, JC; Mooij, HL; Nieuwdorp, M; Stroes, ES; van Haeften, TW; van Lieshout, MH; Vink, H1
Weinbroum, AA1
De Vriese, AS; Van Praet, JT1
Al Otaibi, T; Hussain, N; Nampoory, MR1
Gradoń, L; Odziomek, M; Sosnowski, TR1
Bas, E; Bauer, B; Eshraghi, AA; Guardiola, M; Mittal, J; Rivera, I; Roell, J; Shaikh, N; Telischi, FF; Van De Water, T1
Button, BM; Holland, AE; Le Maitre, C; Romero, L; Steward, R; Tarrant, BJ; Thompson, BR1
Icard, BL; Rubio, E1
Hupp, S; Luckett, P; Papacostas, MF1
Bunchorntavakul, C; Reddy, KR1
Charron, CS; Jeffery, EH; Novotny, JA; Ross, SA; Seifried, HE; Vinyard, BT1
Baldwin, GS; Bolton, DM; Ischia, JJ; O'Kane, D; Patel, O1
Amiot, BP; Chen, HS; Joo, DJ; Li, Y; Nyberg, SL; Rinaldo, P; Shaheen, M1
Davidopoulou, S; Kalogirou, TE; Meditskou, S; Pitoulias, AG; Pitoulias, GA; Savvas, I1
Mancini, L; Paolantoni, M; Ricci, M; Schoubben, A1

Reviews

14 review(s) available for acetylcysteine and mannitol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Prevention and nondialytic treatment of acute renal failure.
    Current opinion in critical care, 2003, Volume: 9, Issue:6

    Topics: Acetylcysteine; Acute Kidney Injury; Calcium Channel Blockers; Crush Syndrome; Diuretics; Fluid Therapy; Free Radical Scavengers; Growth Substances; Humans; Kidney Tubular Necrosis, Acute; Mannitol; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2003
A review of pharmacologic interventions to prevent contrast-induced nephropathy.
    Reviews in cardiovascular medicine, 2003, Volume: 4 Suppl 5

    Topics: Acetylcysteine; Adenosine; Calcium Channel Blockers; Contrast Media; Creatinine; Fenoldopam; Furosemide; Hemodynamics; Humans; Kidney Diseases; Mannitol; Prostaglandins

2003
Acute renal failure.
    Clinical evidence, 2003, Issue:10

    Topics: Acetylcysteine; Acute Kidney Injury; Aminoglycosides; Calcium Channel Blockers; Diuretics; Dopamine; Dopamine Agonists; Fenoldopam; Fluid Therapy; Humans; Mannitol; Renal Replacement Therapy; Theophylline

2003
New pharmacological protocols to prevent or reduce contrast media nephropathy.
    Minerva cardioangiologica, 2005, Volume: 53, Issue:1

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Contrast Media; Diuretics; Fluid Therapy; Furosemide; Humans; Incidence; Kidney; Mannitol; Renal Insufficiency; Vasoconstriction; Vasodilator Agents

2005
Acute renal failure.
    Clinical evidence, 2005, Issue:13

    Topics: Acetylcysteine; Acute Kidney Injury; Aminoglycosides; Amphotericin B; Calcium Channel Blockers; Diuretics, Osmotic; Dopamine; Fenoldopam; Fluid Therapy; Humans; Mannitol; Natriuretic Peptides; Renal Dialysis; Renal Replacement Therapy; Sodium Potassium Chloride Symporter Inhibitors; Theophylline

2005
Renal failure (acute).
    Clinical evidence, 2006, Issue:15

    Topics: Acetylcysteine; Acute Kidney Injury; Aminoglycosides; Aminophylline; Amphotericin B; Calcium Channel Blockers; Diuretics, Osmotic; Dopamine; Fenoldopam; Fluid Therapy; Humans; Mannitol; Natriuretic Peptides; Renal Dialysis; Renal Replacement Therapy; Theophylline

2006
Prevention of contrast-induced nephropathy: a critical review.
    Current opinion in nephrology and hypertension, 2007, Volume: 16, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Contrast Media; Creatinine; Diuretics; Evidence-Based Medicine; Fluid Therapy; Humans; Mannitol; Metformin; Osmolar Concentration; Randomized Controlled Trials as Topic; Renal Replacement Therapy; Risk Factors; Theophylline; Viscosity

2007
Contrast media nephropathy: in depth review.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2008, Volume: 19, Issue:2

    Topics: Acetylcysteine; Calcium Channel Blockers; Contrast Media; Diabetic Nephropathies; Dopamine; Endothelin Receptor Antagonists; Humans; Kidney Diseases; Mannitol; Renal Insufficiency; Risk Factors

2008
Mucoactive agents for chronic, non-cystic fibrosis lung disease: A systematic review and meta-analysis.
    Respirology (Carlton, Vic.), 2017, Volume: 22, Issue:6

    Topics: Acetylcysteine; Administration, Inhalation; Bronchiectasis; Chronic Disease; Deoxyribonuclease I; Expectorants; Forced Expiratory Volume; Humans; Lung Diseases; Mannitol; Mesna; Mucociliary Clearance; Quality of Life; Recombinant Proteins; Saline Solution, Hypertonic; Symptom Flare Up; Vital Capacity

2017
The role of mucoactive agents in the mechanically ventilated patient: a review of the literature.
    Expert review of respiratory medicine, 2017, Volume: 11, Issue:10

    Topics: Acetylcysteine; Ambroxol; Critical Care; Critical Illness; Deoxyribonuclease I; Expectorants; Guaifenesin; Humans; Intensive Care Units; Mannitol; Mucociliary Clearance; Potassium Dichromate; Recombinant Proteins; Respiration, Artificial; Saline Solution, Hypertonic; Sodium Bicarbonate

2017
The use of pulmonary clearance medications in the acutely ill patient.
    Expert review of respiratory medicine, 2017, Volume: 11, Issue:10

    Topics: Acetylcysteine; Cystic Fibrosis; Deoxyribonuclease I; Expectorants; Heparin; Humans; Lung; Mannitol; Mucociliary Clearance; Recombinant Proteins; Saline Solution, Hypertonic; Smoke Inhalation Injury

2017
Acute Liver Failure.
    Clinics in liver disease, 2017, Volume: 21, Issue:4

    Topics: Acetylcysteine; Brain Edema; Chemical and Drug Induced Liver Injury; Clinical Protocols; Critical Care; Disease Management; Diuretics, Osmotic; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Intracranial Hypertension; Liver Failure, Acute; Liver Transplantation; Mannitol; Saline Solution, Hypertonic; Time Factors

2017
Preconditioning against renal ischaemia reperfusion injury: the failure to translate to the clinic.
    Journal of nephrology, 2019, Volume: 32, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Chelating Agents; Disease Models, Animal; Diuretics, Osmotic; Endpoint Determination; Free Radical Scavengers; Humans; Hypoxia-Inducible Factor 1; Ischemic Preconditioning; Kidney; Mannitol; Oligopeptides; Reperfusion Injury; Reproducibility of Results; Translational Research, Biomedical

2019

Trials

3 trial(s) available for acetylcysteine and mannitol

ArticleYear
Can renal dysfunction after infra-renal aortic aneurysm repair be modified by multi-antioxidant supplementation?
    The Journal of cardiovascular surgery, 2002, Volume: 43, Issue:4

    Topics: Acetylcysteine; Aged; Albuminuria; Allopurinol; Antioxidants; Aortic Aneurysm, Abdominal; Ascorbic Acid; Female; Humans; Kidney Function Tests; Male; Mannitol; Prospective Studies; Renal Insufficiency; Reperfusion Injury; Vitamin E

2002
Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo.
    Diabetes, 2006, Volume: 55, Issue:2

    Topics: Acetylcysteine; Adult; Blood Coagulation; Dextrans; Endothelial Cells; Glucose; Glucose Clamp Technique; Glycocalyx; Humans; Hyperglycemia; Male; Mannitol; Time Factors

2006
Absorption and metabolism of isothiocyanates formed from broccoli glucosinolates: effects of BMI and daily consumption in a randomised clinical trial.
    The British journal of nutrition, 2018, Volume: 120, Issue:12

    Topics: Acetylcysteine; Adult; Aged; Anticarcinogenic Agents; Area Under Curve; Body Mass Index; Brassica; Cooking; Cross-Over Studies; Diet; Female; Genotype; Glucose; Glucosinolates; Glutathione Transferase; Glycoside Hydrolases; Humans; Imidoesters; Isothiocyanates; Male; Mannitol; Middle Aged; Oximes; Raphanus; Sulfides; Sulfoxides; Tandem Mass Spectrometry; Thiocyanates

2018

Other Studies

21 other study(ies) available for acetylcysteine and mannitol

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The role of oxygen-derived free radicals in the cytotoxicity of doxorubicin in multidrug resistant and sensitive human ovarian cancer cells.
    Cancer letters, 1988, Aug-15, Volume: 41, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Benzoates; Benzoic Acid; Catalase; Cell Division; Cell Survival; Doxorubicin; Drug Resistance; Female; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Kinetics; Mannitol; Ovarian Neoplasms; Oxygen; Superoxide Dismutase; Tumor Cells, Cultured

1988
Effects of antioxidants on oxidant-induced sister chromatid exchange formation.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:6

    Topics: Acetylcysteine; Animals; Benzoates; Benzoic Acid; beta Carotene; Carotenoids; Catalase; Cricetinae; Cricetulus; Female; Free Radicals; Glutathione; Humans; Mannitol; Ovary; Oxygen; Phagocytes; Selenious Acid; Selenium; Sister Chromatid Exchange; Superoxide Dismutase; Vitamin E; Xanthine Oxidase

1985
Effects of oxygen radical scavengers and antioxidants on phagocyte-induced mutagenesis.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 128, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Benzoates; Benzoic Acid; Catalase; Cattle; Cysteine; Free Radicals; Humans; Mannitol; Mutagenicity Tests; Oxygen; Phagocytes; Salmonella; Superoxide Dismutase

1982
Cerebral blood flow and metabolism in fulminant liver failure.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adult; Blood Flow Velocity; Brain; Brain Edema; Drug Overdose; Epoprostenol; Female; Glucose; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Lactates; Male; Mannitol; Middle Aged; Oxygen; Regional Blood Flow; Respiration, Artificial

1994
Down-regulation of human immunodeficiency virus type (HIV-1) production after stimulation of monocyte-derived macrophages infected with HIV-1.
    The Journal of infectious diseases, 1993, Volume: 167, Issue:4

    Topics: Acetylcysteine; Cell Survival; Cells, Cultured; Down-Regulation; HIV Core Protein p24; HIV-1; Humans; Luminescent Measurements; Macrophage Activation; Macrophages; Mannitol; Oxidation-Reduction; Phagocytosis; Superoxide Dismutase; Virus Replication

1993
Reduction of ischemia-reperfusion syndrome after abdominal aortic aneurysmectomy by N-acetylcysteine but not mannitol.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:6

    Topics: Acetylcysteine; Aged; Aortic Aneurysm, Abdominal; Epoprostenol; Free Radical Scavengers; Hemodynamics; Humans; Mannitol; Middle Aged; Oxidative Stress; Pilot Projects; Postoperative Complications; Reperfusion Injury; Thromboxane A2

1996
Acute paraquat poisoning: increased toxicity in one case with high alcohol intake.
    Human & experimental toxicology, 1998, Volume: 17, Issue:3

    Topics: Acetylcysteine; Alcohol Drinking; Antidotes; Deferoxamine; Diuretics, Osmotic; Ethanol; Excipients; Expectorants; Fatal Outcome; Herbicides; Humans; Male; Mannitol; Middle Aged; Paraquat; Polyethylene Glycols

1998
780 nm low power diode laser irradiation stimulates proliferation of keratinocyte cultures: involvement of reactive oxygen species.
    Lasers in surgery and medicine, 1998, Volume: 22, Issue:4

    Topics: Acetates; Acetylcysteine; Antioxidants; Catalase; Cell Count; Cell Division; Cells, Cultured; Enzyme Inhibitors; Follow-Up Studies; Free Radical Scavengers; Histidine; Humans; Hydrogen Peroxide; Hydroxyl Radical; Keratinocytes; Lasers; Lipid Peroxidation; Mannitol; Radiopharmaceuticals; Reactive Oxygen Species; Sodium Azide; Superoxide Dismutase; Superoxides; Thymidine; Tritium; Vitamin E

1998
High-glucose-induced nuclear factor kappaB activation in vascular smooth muscle cells.
    Cardiovascular research, 2000, Volume: 46, Issue:1

    Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Cells, Cultured; Diabetic Angiopathies; Enzyme Inhibitors; Glucose; Glutathione; Indoles; Male; Maleimides; Mannitol; Muscle, Smooth, Vascular; NF-kappa B; Protein Kinase C; Rats; Rats, Wistar; Stimulation, Chemical; Time Factors; Tumor Necrosis Factor-alpha

2000
Adverse effects of oxidative stress on renal cells and its prevention by antioxidants.
    Molecular urology, 2000,Spring, Volume: 4, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cell Line; Cell Survival; HSP90 Heat-Shock Proteins; Hydrogen Peroxide; Kidney Tubules, Proximal; Kinetics; Lipid Peroxidation; Malondialdehyde; Mannitol; Oxidative Stress; Pyruvates; Swine

2000
Reversal of cadmium induced oxidative stress by chelating agent, antioxidant or their combination in rat.
    Toxicology letters, 2003, Dec-10, Volume: 145, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Brain; Cadmium Chloride; Cadmium Poisoning; Catalase; Chelating Agents; Drug Synergism; Drug Therapy, Combination; Glutathione; Liver; Male; Malondialdehyde; Mannitol; Oxidative Stress; Rats; Succimer; Superoxide Dismutase

2003
The evaluation of the protective action of antioxidants on small intestine of rabbits experimentally injured by ischemia and reperfusion.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Edema; Hemorrhage; Intestinal Mucosa; Intestine, Small; Ischemia; Ligation; Male; Mannitol; Mesenteric Artery, Superior; Oxidative Stress; Rabbits; Reperfusion Injury

2004
Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in nickel sulfate-induced human lymphocyte death in vitro.
    Chemico-biological interactions, 2005, Sep-10, Volume: 156, Issue:1

    Topics: Acetylcysteine; Calcium; Catalase; Cell Death; Cyclosporine; Deferoxamine; Glutathione; Homeostasis; Humans; Hydrogen Peroxide; Lymphocytes; Mannitol; Membrane Potentials; Mitochondria; Nickel; Oxidative Stress; Thiourea

2005
Concomitant administration of mannitol and N-acetylcysteine for the prevention of lung reperfusion injury.
    The Journal of trauma, 2006, Volume: 60, Issue:6

    Topics: Acetylcysteine; Animals; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Free Radical Scavengers; Ischemia; Liver; Lung; Male; Mannitol; Rats; Rats, Wistar; Reperfusion Injury

2006
Conception, preparation and properties of functional carrier particles for pulmonary drug delivery.
    International journal of pharmaceutics, 2012, Aug-20, Volume: 433, Issue:1-2

    Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Dextrans; Drug Carriers; Drug Delivery Systems; Drug Stability; Drug Storage; Dry Powder Inhalers; Expectorants; Humidity; Mannitol; Microscopy, Electron, Scanning; Particle Size; Phase Transition; Powders; Temperature; Thermodynamics; Tissue Distribution

2012
A novel combination of drug therapy to protect residual hearing post cochlear implant surgery.
    Acta oto-laryngologica, 2016, Volume: 136, Issue:4

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Cochlear Implantation; Dexamethasone; Drug Therapy, Combination; Free Radical Scavengers; Hair Cells, Auditory; Hearing Loss; Mannitol; Postoperative Complications; Rats, Sprague-Dawley

2016
Cold storage of porcine hepatocyte spheroids for spheroid bioartificial liver.
    Xenotransplantation, 2019, Volume: 26, Issue:4

    Topics: Acetylcysteine; Albumins; Ammonia; Animals; Cryopreservation; Deferoxamine; Glucose; Hepatocytes; Iron Chelating Agents; Liver, Artificial; Mannitol; Metabolic Clearance Rate; Organ Preservation Solutions; Oxidation-Reduction; Potassium Chloride; Procaine; Spheroids, Cellular; Swine; Transplantation, Heterologous

2019
Investigating the Possible Protective Role of Direct Intra-arterial Administration of Mannitol and N-Acetylcysteine and Per Os Administration of Simvastatin Against Contrast-Induced Nephropathy: An Experimental Study in a Rabbit Model.
    Cardiovascular and interventional radiology, 2019, Volume: 42, Issue:12

    Topics: Acetylcysteine; Acute Kidney Injury; Administration, Oral; Animals; Contrast Media; Disease Models, Animal; Diuretics, Osmotic; Humans; Infusions, Intra-Arterial; Iohexol; Male; Mannitol; Rabbits; Simvastatin

2019
Development of spray-dried N-acetylcysteine dry powder for inhalation.
    International journal of pharmaceutics, 2023, Jan-25, Volume: 631

    Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Dry Powder Inhalers; Leucine; Mannitol; Particle Size; Powders

2023