acetylcysteine has been researched along with losartan in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 12 (57.14) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Fujimiya, T; Naito, K; Shiraishi, K; Yoshida, K | 1 |
| Crespo, MJ; Escobales, N | 1 |
| Chen, P; Edwards, PA; Guo, AM; Scicli, AG; Trick, G | 1 |
| Akita, Y; Iwasaka, T; Matsuhisa, S; Moriguchi, A; Okazaki, T; Otani, H; Sato, D; Yamashita, K | 1 |
| Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, B | 1 |
| Jiao, S; Wang, L; Yang, X; Zhang, J; Zheng, X | 1 |
| Aghamohammadzadeh, N; Heydarnejad, M; Khalaj, MR; Mobasseri, M; Noshad, H; Rasi Hashemi, S; Tabrizi, A; Tayebi Khosroshahi, H | 1 |
| Feng, L; Liu, J; Pang, X; Wang, S; Wu, D; Zhang, X; Zhao, J | 1 |
| Miyake, S; Nagai, N; Narimatsu, T; Ozawa, Y; Tsubota, K | 1 |
| Dopona, EP; Furukawa, LN; Heimann, JC; Katayama, IA; Oliveira, IB; Pereira, RC; Shimizu, MH | 1 |
| Cha, SK; Chung, CH; Kang, JS; Kim, JH; Lee, ES; Lee, EY; Lee, JH; Lee, SJ; Son, SS | 1 |
| Gong, DS; Lee, HH; Oak, MH; Park, SH; Schini-Kerth, V; Sharma, K; Yi, E | 1 |
| Chen, AD; Chen, Q; Kang, YM; Li, YH; Qiu, Y; Wang, JJ; Ye, C; Zheng, F; Zhu, GQ | 1 |
| Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M | 1 |
2 review(s) available for acetylcysteine and losartan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Ceftriaxone; Dibenzazepines; Drug Repositioning; Epilepsy; Epilepsy, Post-Traumatic; Erythropoietin; Fingolimod Hydrochloride; GABA Agents; Gabapentin; Humans; Immunologic Factors; Inflammation; Interleukin 1 Receptor Antagonist Protein; Isoflurane; Levetiracetam; Losartan; Neuroprotective Agents; Oxidative Stress; Pregabalin; Pyrrolidinones; Sirolimus; Stroke; Topiramate; Translational Research, Biomedical; Vigabatrin | 2020 |
1 trial(s) available for acetylcysteine and losartan
| Article | Year |
|---|---|
Angiotensin receptor blocker and N-acetyl cysteine for reduction of proteinuria in patients with type 2 diabetes mellitus.
Topics: Acetylcysteine; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Losartan; Male; Middle Aged; Proteinuria; Statistics, Nonparametric | 2012 |
18 other study(ies) available for acetylcysteine and losartan
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Angiotensin II dependent testicular fibrosis and effects on spermatogenesis after vasectomy in the rat.
Topics: Acetylcysteine; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Enalapril; Fibrosis; Heat-Shock Proteins; HSP47 Heat-Shock Proteins; Leydig Cells; Losartan; Male; Rats; Rats, Wistar; Spermatogenesis; Testis; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vasectomy | 2003 |
Angiotensin II-dependent vascular alterations in young cardiomyopathic hamsters: role for oxidative stress.
Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aorta; Blood Pressure; Cardiomyopathies; Cricetinae; Disease Models, Animal; Losartan; Male; Mesocricetus; NADPH Oxidases; Oxidative Stress; Superoxides | 2006 |
Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.
Topics: Acetophenones; Acetylcysteine; Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Imidazoles; Indoles; Leukostasis; Losartan; Male; NADPH Oxidases; Pyridines; Pyrroles; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retinal Diseases; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents | 2007 |
N-acetylcysteine abolishes the protective effect of losartan against left ventricular remodeling in cardiomyopathy hamster.
Topics: Acetylcysteine; Amidines; Angiotensin II Type 1 Receptor Blockers; Animals; Benzylamines; Cardiomyopathies; Cricetinae; Drug Interactions; Enzyme Inhibitors; Fibrosis; Free Radical Scavengers; Heart; Heart Ventricles; Losartan; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Ventricular Function, Left; Ventricular Remodeling | 2008 |
Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.
Topics: Acetylcysteine; Angiotensin II; Antihypertensive Agents; C-Reactive Protein; Flavonoids; Humans; Imidazoles; Losartan; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Pyridines; Thiocarbamates; U937 Cells | 2011 |
Losartan inhibits STAT1 activation and protects human glomerular mesangial cells from angiotensin II induced premature senescence.
Topics: Acetylcysteine; Angiotensin II; beta-Galactosidase; Cell Cycle Checkpoints; Cell Line; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Gene Knockdown Techniques; Humans; Losartan; Mesangial Cells; Reactive Oxygen Species; Signal Transduction; STAT1 Transcription Factor; Tumor Suppressor Protein p53 | 2012 |
Angiotensin II induces C-reactive protein expression via AT1-ROS-MAPK-NF-κB signal pathway in hepatocytes.
Topics: Acetylcysteine; Angiotensin II; Animals; C-Reactive Protein; Cell Line; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Recombinant Proteins; RNA, Messenger; Signal Transduction; Thenoyltrifluoroacetone | 2013 |
Angiotensin II type 1 receptor blockade suppresses light-induced neural damage in the mouse retina.
Topics: Acetylcysteine; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Apoptosis; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Fas Ligand Protein; Gene Expression Regulation; Light; Losartan; Male; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-fos; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Retinal Degeneration; Retinal Photoreceptor Cell Outer Segment; Signal Transduction; Tetrazoles; Valine; Valsartan | 2014 |
High-salt intake induces cardiomyocyte hypertrophy in rats in response to local angiotensin II type 1 receptor activation.
Topics: Acetylcysteine; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hematocrit; Hydralazine; Losartan; Male; Myocytes, Cardiac; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Thiobarbituric Acid Reactive Substances | 2014 |
Angiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease.
Topics: Acetylcysteine; Actin Cytoskeleton; Angiotensin II; Animals; Calcium; Cell Adhesion; Cell Line, Transformed; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Down-Regulation; Humans; Losartan; Mice; Mice, Inbred C57BL; Microfilament Proteins; Molecular Motor Proteins; Myosin Heavy Chains; NADPH Oxidase 4; Podocytes; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Receptors, Leptin; RNA Interference; TRPC6 Cation Channel | 2019 |
Fine air pollution particles induce endothelial senescence via redox-sensitive activation of local angiotensin system.
Topics: Acetylcysteine; Air Pollution; Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Antioxidants; beta-Galactosidase; Blood Platelets; Cell Cycle Checkpoints; Cell Division; Cell Proliferation; Cells, Cultured; Cellular Senescence; Coronary Vessels; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Losartan; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Particulate Matter; Receptor, Angiotensin, Type 1; Swine | 2019 |
Angiotensin Type 1 Receptors and Superoxide Anion Production in Hypothalamic Paraventricular Nucleus Contribute to Capsaicin-Induced Excitatory Renal Reflex and Sympathetic Activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Acetylcysteine; Allopurinol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Capsaicin; Captopril; Ditiocarb; Kidney; Losartan; Male; NADPH Oxidases; Onium Compounds; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Superoxides | 2020 |