acetylcysteine and lidocaine

acetylcysteine has been researched along with lidocaine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's2 (12.50)18.2507
2000's6 (37.50)29.6817
2010's7 (43.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dempsey, DT; Mercer, DW; Ritchie, WP1
Aleĭnikov, VG; Burushkina, TN; Evdokimenko, VM; Kokarovtseva, MG; Stavinskiĭ, VB1
Borzone, S; Caglieris, S; Ghia, M; Giannini, E; Mattioli, F; Mereto, E; Risso, D; Testa, R1
Haertel, C; Lenhart, A; Meier-Hellmann, A; Michel, C; Rank, N; Spies, C; Welte, M1
Beghetti, M; Giger, R; Lacroix, JS; Landis, BN; Morel, DR; Rimensberger, PC1
Del Sorbo, L; Zhang, H1
Armstrong, VW; Hein, OV; Kox, WJ; Oellerich, M; Ohring, R; Schilling, A; Spies, C1
Hirota, K; Kusunoki, M; Matsuo, Y; Nishi, K; Okamoto, A; Oku, K; Shingu, K; Sumi, C; Takenaga, K; Tanaka, M1
Almacioglu, M; Demirkasimoglu, M; Eyison, RK; Ivelik, K; Kenar, L; Kunak, ZI; Ortatatli, M; Sezigen, S1

Reviews

1 review(s) available for acetylcysteine and lidocaine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for acetylcysteine and lidocaine

ArticleYear
N-acetylcysteine increases liver blood flow and improves liver function in septic shock patients: results of a prospective, randomized, double-blind study.
    Critical care medicine, 2000, Volume: 28, Issue:12

    Topics: Acetylcysteine; Adult; Aged; Blood Flow Velocity; Coloring Agents; Double-Blind Method; Female; Free Radical Scavengers; Hemodynamics; Humans; Indocyanine Green; Infusions, Intravenous; Injections, Intravenous; Lidocaine; Liver; Liver Circulation; Liver Function Tests; Male; Metabolic Clearance Rate; Microsomes, Liver; Middle Aged; Oxygen Consumption; Prospective Studies; Shock, Septic; Survival Analysis

2000

Other Studies

14 other study(ies) available for acetylcysteine and lidocaine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Do sensory neurons mediate adaptive cytoprotection of gastric mucosa against bile acid injury?
    American journal of surgery, 1992, Volume: 163, Issue:1

    Topics: Acetylcysteine; Adaptation, Physiological; Animals; Bile Acids and Salts; DNA; Gastric Mucosa; Lidocaine; Mucus; Neurons, Afferent; Rats; Rats, Inbred Strains; Taurocholic Acid

1992
[Adsorption of antidotes by carbon hemosorbents].
    Vrachebnoe delo, 1984, Issue:2

    Topics: Acetylcysteine; Aconitine; Adsorption; Antidotes; Charcoal; Cysteine; Hemoperfusion; In Vitro Techniques; Kinetics; Lidocaine

1984
Effects of reduced glutathione and n-acetylcysteine on lidocaine metabolism in cimetidine treated rats.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2

    Topics: Acetylcysteine; Anesthetics, Local; Animals; Cimetidine; Drug Interactions; Fluorescence Polarization Immunoassay; Free Radical Scavengers; Glutathione; Histamine H2 Antagonists; Injections, Intraperitoneal; Lidocaine; Rats; Rats, Sprague-Dawley; Time Factors

1998
Somato-sympathetic vasoconstriction to intranasal fluid administration with consecutive decrease in nasal nitric oxide.
    Acta physiologica Scandinavica, 2003, Volume: 177, Issue:4

    Topics: Acetylcysteine; Administration, Intranasal; Adult; Anesthetics, Local; Chronic Disease; Expectorants; Female; Histamine; Humans; Laser-Doppler Flowmetry; Lidocaine; Male; Middle Aged; Nasal Mucosa; Nebulizers and Vaporizers; Nitric Oxide; Reflex; Sinusitis; Sodium Chloride; Sympathetic Nervous System; Vasoconstriction

2003
Is there a place for N-acetylcysteine in the treatment of septic shock?
    Critical care (London, England), 2004, Volume: 8, Issue:2

    Topics: Acetylcysteine; Antioxidants; Hemodynamics; Humans; Lidocaine; Liver; Liver Circulation; Shock, Septic

2004
N-acetylcysteine decreases lactate signal intensities in liver tissue and improves liver function in septic shock patients, as shown by magnetic resonance spectroscopy: extended case report.
    Critical care (London, England), 2004, Volume: 8, Issue:2

    Topics: Acetylcysteine; Adult; Aged; Antioxidants; Female; Hemodynamics; Humans; Lactates; Lidocaine; Liver; Liver Circulation; Liver Function Tests; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oxygen Consumption; Prospective Studies; Shock, Septic; Signal Transduction; Survival Analysis; Vasoconstriction

2004
The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells.
    BMC anesthesiology, 2016, 10-24, Volume: 16, Issue:1

    Topics: Acetylcysteine; Anesthetics, Local; Antioxidants; Apoptosis; Bupivacaine; Cell Death; Cell Line, Tumor; Cell Survival; Chromans; Dose-Response Relationship, Drug; HeLa Cells; Humans; Lidocaine; Membrane Potential, Mitochondrial; Mepivacaine; Mitochondria; Neuroblastoma; Reactive Oxygen Species; Time Factors

2016
Victims of chemical terrorism, a family of four who were exposed to sulfur mustard.
    Toxicology letters, 2019, Mar-15, Volume: 303

    Topics: Acetaminophen; Acetylcysteine; Administration, Cutaneous; Administration, Inhalation; Adult; Albuterol; Asian People; Chemical Terrorism; Child, Preschool; Cyclopentolate; Female; Gentamicins; Humans; Infant, Newborn; Lidocaine; Male; Methylprednisolone; Mustard Gas; Silver Sulfadiazine; Skin; Syria; Terrorism; Turkey

2019