acetylcysteine has been researched along with levodopa in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Glatt, H | 1 |
| Hisaka, A; Kasamatsu, S; Ohtawa, M; Takenaga, N | 1 |
| De Natale, G; Delogu, MR; Desole, MS; Godani, C; Miele, E; Migheli, R; Sciola, L; Serra, PA; Zangani, D | 1 |
| Delogu, MR; Desole, MS; Enrico, P; Esposito, G; Grella, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, PA | 1 |
| Jenner, P; McNaught, KS | 1 |
| Bermak, J; Weingarten, P; Zhou, QY | 1 |
| Hong, JT; Kang, MH; Kim, YM; Lee, JJ; Lee, MK; Park, HD; Yin, SY | 1 |
| Jin, CM; Kai, M; Kang, MH; Kim, YM; Lee, JJ; Lee, MK; Yang, YJ; Yin, SY | 1 |
| Han, Y; Lau, AS; Qi, H; Rong, J; Zhao, J | 1 |
| Martínez-Banaclocha, MA | 1 |
| Czarnecka, A; Kamińska, K; Konieczny, J; Lenda, T; Lorenc-Koci, E | 1 |
| Furlong, TM; Gibson, AS; Keefe, KA | 1 |
18 other study(ies) available for acetylcysteine and levodopa
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Endogenous mutagens derived from amino acids.
Topics: Acetylcysteine; Amino Acids; Animals; Cells, Cultured; Homogentisic Acid; Levodopa; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Tyrosine | 1990 |
Quantification of L-3-(3-hydroxy-4-pivaloyloxyphenyl)alanine (NB-355) by high-performance liquid chromatography using o-phthalaldehyde/N-acetyl-L-cysteine derivatization.
Topics: Acetylcysteine; Animals; Biological Availability; Carbidopa; Chromatography, High Pressure Liquid; Dogs; Levodopa; Male; o-Phthalaldehyde; Prodrugs | 1989 |
Enhancing effect of manganese on L-DOPA-induced apoptosis in PC12 cells: role of oxidative stress.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Survival; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Drug Synergism; Flow Cytometry; Levodopa; Manganese Poisoning; Oxidative Stress; PC12 Cells; Rats | 1999 |
Manganese increases L-DOPA auto-oxidation in the striatum of the freely moving rat: potential implications to L-DOPA long-term therapy of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Chlorides; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis Solutions; Dopamine; Homovanillic Acid; Infusion Pumps; Levodopa; Male; Manganese; Manganese Compounds; Microdialysis; Movement; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Wistar; Time Factors; Uric Acid | 2000 |
Proteasomal function is impaired in substantia nigra in Parkinson's disease.
Topics: Acetylcysteine; Aged; Cysteine Endopeptidases; Dihydroxyphenylalanine; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Hydrolysis; Levodopa; Lewy Bodies; Male; Multienzyme Complexes; Parkinson Disease; Peptide Hydrolases; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Substantia Nigra; Ubiquitins | 2001 |
Evidence for non-oxidative dopamine cytotoxicity: potent activation of NF-kappa B and lack of protection by anti-oxidants.
Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Aromatic-L-Amino-Acid Decarboxylases; Aspirin; Cell Survival; CHO Cells; Clone Cells; Cricetinae; Dopamine; Glutathione; L-Lactate Dehydrogenase; Levodopa; Lipid Peroxidation; Malondialdehyde; NF-kappa B; Recombinant Proteins | 2001 |
Aggravation of L-DOPA-induced neurotoxicity by tetrahydropapaveroline in PC12 cells.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Apoptosis; Cell Survival; Dopamine Agents; Drug Interactions; Levodopa; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Tetrahydropapaveroline | 2003 |
Effects of (1R,9S)-beta-hydrastine on l-DOPA-induced cytotoxicity in PC12 cells.
Topics: Acetylcysteine; Alkaloids; Animals; Antioxidants; Apoptosis; Benzylisoquinolines; Cell Death; Cell Survival; DNA Fragmentation; Dopamine Agents; Flow Cytometry; Free Radical Scavengers; Isomerism; Levodopa; PC12 Cells; Rats | 2004 |
Z-ligustilide potentiates the cytotoxicity of dopamine in rat dopaminergic PC12 cells.
Topics: 4-Butyrolactone; Acetylcysteine; Animals; Apoptosis; Bisbenzimidazole; Cell Count; DNA Fragmentation; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Glutathione; Levodopa; Neuroprotective Agents; PC12 Cells; Rats; Reactive Oxygen Species; Time Factors | 2012 |
N-acetyl-cysteine in the treatment of Parkinson's disease. What are we waiting for?
Topics: Acetylcysteine; Animals; Drug Therapy, Combination; Glutathione; Humans; Levodopa; Models, Theoretical; Oxidative Stress; Parkinson Disease | 2012 |
Chronic L-DOPA treatment attenuates behavioral and biochemical deficits induced by unilateral lactacystin administration into the rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Catalepsy; Cysteine Proteinase Inhibitors; Dopamine Agonists; Dose-Response Relationship, Drug; Functional Laterality; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Reaction Time; Serotonin; Substantia Nigra | 2014 |
Accelerated habitual learning resulting from L-dopa exposure in rats is prevented by N-acetylcysteine.
Topics: Acetylcysteine; Animals; Antioxidants; Behavior, Addictive; Behavior, Animal; Conditioning, Operant; Dopamine; Dopamine Agents; Glutamic Acid; Habits; Levodopa; Male; Motor Activity; Parkinson Disease; Rats; Rats, Long-Evans | 2020 |