acetylcysteine has been researched along with lead in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.13) | 18.7374 |
| 1990's | 4 (10.26) | 18.2507 |
| 2000's | 12 (30.77) | 29.6817 |
| 2010's | 17 (43.59) | 24.3611 |
| 2020's | 4 (10.26) | 2.80 |
| Authors | Studies |
|---|---|
| Ottenwälder, H; Simon, P | 1 |
| Banner, W; Capin, DM; Chang, S; Hopf, SB; Koch, M; Tong, TG | 1 |
| Ercal, N; Hammond, TC; Lutz, P; Matthews, RH; Treeratphan, P | 1 |
| Ercal, N; Grannemann, NH; Hammond, TC; Matthews, RH; Spitz, DR; Treeratphan, P | 1 |
| Galdzicki, Z; Hanbauer, I; Rapoport, SI; Scortegagna, M | 1 |
| Erçal, N; Gürer, H; Neal, R; Ozgünes, H; Spitz, DR | 1 |
| Fu, S; Li, H | 1 |
| Prasad, S; Siddiqui, MK; Singh, S; Srivastava, S; Tandon, SK | 1 |
| Flora, SJ; Kannan, GM; Mehta, A; Pande, M | 1 |
| Kanwar, SS; Nehru, B | 1 |
| Aykin-Burns, N; Ercal, N; Franklin, EA | 1 |
| Banks, WA; Ercal, N; Lutz, P; Mare, S; Penugonda, S | 1 |
| Dong, T; Li, Z; Noble, M; Pröschel, C | 1 |
| Flora, G; Flora, SJ; Mishra, M; Saxena, G | 1 |
| Tchounwou, PB; Yedjou, CG | 1 |
| Duydu, Y; Ustundag, A | 1 |
| Aytekin, M; Caylak, E; Halifeoglu, I | 1 |
| Calderón-Cabrera, L; Durán-Galetta, MG; Ferreira, E; Galetta, D; Garcia, I; Lacruz, L; Naranjo, R; Pérez, B | 1 |
| Edwards, F; Haile, S; Tchounwou, CK; Tchounwou, PB; Yedjou, CG | 1 |
| Ercal, N; Penugonda, S | 1 |
| Chen, D; Li, J; Liu, Z; Wang, H; Wang, L | 1 |
| Emilio, R; Mahara, V; Martín, SA | 1 |
| Chen, W; Chusuei, CC; Ercal, N; Huynh, T; Volkov, A | 1 |
| Birkner, E; Dobrakowski, M; Kasperczyk, A; Kasperczyk, S; Ostałowska, A | 1 |
| Sharma, S; Shrivastava, S; Shukla, S | 1 |
| Birkner, E; Dobrakowski, M; Kasperczyk, A; Kasperczyk, S; Machnik, G | 1 |
| Raghuvanshi, BP; Sharma, S; Shukla, S | 1 |
| Li, W; Xue, Y; Zhang, H; Zou, F | 1 |
| Birkner, E; Dobrakowski, M; Kapka-Skrzypczak, L; Kasperczyk, A; Kasperczyk, S; Pawlas, N; Zalejska-Fiolka, J | 1 |
| Agrawal, M; Jahan, S; Khanna, VK; Kumar, V; Pandey, A; Pant, AB; Tripathi, VK | 1 |
| Jiang, L; Liu, Q; Lu, W; Wang, L; Xu, L; Zhi, Y; Zhong, L; Zhou, P | 1 |
| Birkner, E; Dobrakowski, M; Kasperczyk, A; Kasperczyk, S; Pawlas, N; Romuk, E; Rykaczewska-Czerwińska, M | 1 |
| Jalilehvand, F; Sisombath, NS | 1 |
| Aschner, M; Cao, Z; Chen, J; Luo, W; Su, P; Wang, D; Wang, S; Zhang, J; Zhao, F | 1 |
| Banerjee, BD; Chawla, D; Raizada, A; Siddarth, M; Sikka, M; Wadhwa, N | 1 |
| Beigi Harchegani, A; Jaafarzadeh, M; Mahjoob Khaligh, R; Mohsenifar, Z; Rajabi Keleshteri, S; Rezvani Gilkalaei, M; Shabani, A | 1 |
| Abedini Bajgiran, F; Khazaei Koohpar, Z; Salehzadeh, A | 1 |
| Rathinasabapathi, B; Shaheen, H; Tahir, MA | 1 |
| Dafchahi, AB; Harchegani, AB; Jaafarzadeh, M; Moghadam, FM; Mohsenifar, Z; Ranji, N; Rostami, S; Saraabestan, SS | 1 |
1 review(s) available for acetylcysteine and lead
| Article | Year |
|---|---|
Arsenic and lead induced free radical generation and their reversibility following chelation.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Calcium; Chelating Agents; Free Radicals; Humans; Lead; Lead Poisoning; Melatonin; Metals; Micronutrients; Molecular Structure; Succimer; Taurine; Thioctic Acid; Unithiol; Vitamin E | 2007 |
4 trial(s) available for acetylcysteine and lead
| Article | Year |
|---|---|
The administration of N-acetylcysteine reduces oxidative stress and regulates glutathione metabolism in the blood cells of workers exposed to lead.
Topics: Acetylcysteine; Adult; Antioxidants; Erythrocytes; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Reductase; Glutathione Transferase; Humans; Lead; Lead Poisoning; Male; Middle Aged; Occupational Exposure; Oxidative Stress; Young Adult | 2013 |
Effect of N-acetylcysteine administration on the expression and activities of antioxidant enzymes and the malondialdehyde level in the blood of lead-exposed workers.
Topics: Acetylcysteine; Adult; Air Pollutants, Occupational; Antioxidants; Catalase; Glutathione Peroxidase; Humans; Lead; Leukocytes; Male; Malondialdehyde; Middle Aged; Occupational Exposure; Superoxide Dismutase | 2014 |
Effect of treatment with N-acetylcysteine on non-enzymatic antioxidant reserves and lipid peroxidation in workers exposed to lead.
Topics: Acetylcysteine; Adult; Antioxidants; Environmental Pollutants; Free Radical Scavengers; Humans; Lead; Lipid Peroxidation; Male; Middle Aged; Occupational Exposure; Oxidative Stress; Poland | 2014 |
Effect of N-acetylcysteine administration on homocysteine level, oxidative damage to proteins, and levels of iron (Fe) and Fe-related proteins in lead-exposed workers.
Topics: Acetylcysteine; Adult; Air Pollutants, Occupational; Anemia, Iron-Deficiency; Antioxidants; Dietary Supplements; Haptoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Inhalation Exposure; Iron; Lead; Lead Poisoning; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Oxidative Stress; Poland; Protein Carbonylation; Protoporphyrins; Transferrin | 2016 |
34 other study(ies) available for acetylcysteine and lead
| Article | Year |
|---|---|
Differential effect of N-acetylcysteine on excretion of the metals Hg, Cd, Pb and Au.
Topics: Acetylcysteine; Animals; Cadmium; Feces; Gold; Lead; Male; Mercury; Metals; Rats; Rats, Inbred Strains | 1987 |
Experimental chelation therapy in chromium, lead, and boron intoxication with N-acetylcysteine and other compounds.
Topics: Acetylcysteine; Animals; Boric Acids; Chelating Agents; Chromates; Chromium; Female; Kinetics; Lead; Lead Poisoning; Male; Organometallic Compounds; Potassium Dichromate; Rats; Rats, Inbred Strains; Time Factors | 1986 |
N-actylcysteine protects Chinese hamster ovary (CHO) cells from lead-induced oxidative stress.
Topics: Acetylcysteine; Animals; Cell Survival; CHO Cells; Cricetinae; Environmental Pollutants; Free Radical Scavengers; Glutathione; Lead; Lipid Peroxidation; Malondialdehyde; Organometallic Compounds; Oxidative Stress | 1996 |
In vivo indices of oxidative stress in lead-exposed C57BL/6 mice are reduced by treatment with meso-2,3-dimercaptosuccinic acid or N-acetylcysteine.
Topics: Acetylcysteine; Animals; Brain; Cysteine; Glutathione; Lead; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Succimer | 1996 |
In cortical cultures of trisomy 16 mouse brain the upregulated metallothionein-I/II fails to respond to H2O2 exposure or glutamate receptor stimulation.
Topics: Acetylcysteine; Animals; Astrocytes; Blotting, Western; Cerebral Cortex; Excitatory Amino Acid Agonists; Female; Free Radical Scavengers; Hydrogen Peroxide; Lead; Male; Metallothionein; Mice; Mice, Inbred C57BL; Oxidants; Oxidation-Reduction; Receptors, Glutamate; Stimulation, Chemical; Trisomy; Up-Regulation | 1998 |
Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Cell Count; Erythrocytes; Glutathione; Lead; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Inbred F344; Succimer | 1998 |
[Toxicity to neural cell development of lead and its relation to glutathione].
Topics: Acetylcysteine; Animals; Antioxidants; Cell Differentiation; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Glutathione; Lead; Mesencephalon; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley | 2000 |
Reversal of lead-induced oxidative stress by chelating agent, antioxidant, or their combination in the rat.
Topics: Acetylcysteine; Aminolevulinic Acid; Animals; Antioxidants; Brain; Catalase; Chelating Agents; Free Radical Scavengers; Glutathione; Kidney; Lead; Lead Poisoning; Male; Malondialdehyde; Oxidative Stress; Rats; Succimer | 2002 |
Lead induced oxidative stress and its recovery following co-administration of melatonin or N-acetylcysteine during chelation with succimer in male rats.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Chemistry; Chelating Agents; Kidney; Lead; Lead Poisoning; Liver; Male; Melatonin; Oxidative Stress; Rats; Succimer | 2004 |
N-acetylcysteine exposure on lead-induced lipid peroxidative damage and oxidative defense system in brain regions of rats.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Chemistry; Catalase; Female; Free Radical Scavengers; Lead; Lipid Peroxidation; Proteins; Rats; Rats, Wistar; Superoxide Dismutase | 2004 |
Effects of N-acetylcysteine on lead-exposed PC-12 cells.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Glutathione; Glutathione Disulfide; Lead; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; PC12 Cells; Rats; Trypan Blue | 2005 |
Potentiation of lead-induced cell death in PC12 cells by glutamate: protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Calcium Channel Blockers; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Environmental Pollutants; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Lead; Lead Poisoning; Oxidative Stress; PC12 Cells; Phospholipases A; Protein Kinase C; Rats; Reactive Oxygen Species | 2006 |
Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.
Topics: Acetylcysteine; Animals; Cell Division; Cell Nucleus; Cells, Cultured; Environmental Pollutants; Enzyme Activation; Female; Free Radical Scavengers; Lead; Methylmercury Compounds; Mice; Neuroglia; Oxidation-Reduction; Paraquat; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins c-fyn; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Stem Cells | 2007 |
N-acetyl-l-cysteine affords protection against lead-induced cytotoxicity and oxidative stress in human liver carcinoma (HepG2) cells.
Topics: Acetylcysteine; Cell Proliferation; Cell Survival; Chelating Agents; Free Radicals; Humans; Lead; Lipid Peroxidation; Liver Neoplasms; Mutation; Nitrates; Oxidative Stress; Thiobarbiturates | 2007 |
The influence of melatonin and N-acetylcysteine in delta-aminolevulinic acid and lead induced genotoxicity in lymphocytes in vitro.
Topics: Acetylcysteine; Aminolevulinic Acid; Cell Death; Female; Free Radical Scavengers; Humans; Lead; Lymphocytes; Melatonin; Middle Aged; Sister Chromatid Exchange | 2007 |
Antioxidant effects of methionine, alpha-lipoic acid, N-acetylcysteine and homocysteine on lead-induced oxidative stress to erythrocytes in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Chromatography, High Pressure Liquid; Erythrocytes; Glutathione Peroxidase; Hemoglobins; Homocystine; Lead; Male; Malondialdehyde; Methionine; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioctic Acid; Vitamin A; Vitamin E | 2008 |
[Determination of the N-acetylcysteine and methionine effects in the cerebellum of rats intoxicated with lead].
Topics: Acetylcysteine; Animals; Cerebellum; Lead; Lead Poisoning; Male; Methionine; Rats; Rats, Wistar | 2008 |
N-acetyl-cysteine protects against DNA damage associated with lead toxicity in HepG2 cells.
Topics: Acetylcysteine; Cell Survival; Comet Assay; DNA Damage; Free Radical Scavengers; Hep G2 Cells; Humans; Lead; Liver Neoplasms; Oxidative Stress | 2010 |
Comparative evaluation of N-acetylcysteine (NAC) and N-acetylcysteine amide (NACA) on glutamate and lead-induced toxicity in CD-1 mice.
Topics: Acetylcysteine; Animals; Antioxidants; Chelating Agents; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Lead; Male; Malondialdehyde; Mice; Phospholipases A2; Reactive Oxygen Species | 2011 |
Simultaneous effects of lead and cadmium on primary cultures of rat proximal tubular cells: interaction of apoptosis and oxidative stress.
Topics: Acetates; Acetylcysteine; Adenosine Triphosphatases; Animals; Apoptosis; Cadmium; Calcium; Cell Survival; Cells, Cultured; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lead; Lipid Peroxidation; Malondialdehyde; Membrane Potential, Mitochondrial; Necrosis; Organometallic Compounds; Oxidative Stress; Rats; Reactive Oxygen Species | 2011 |
Role of oxidative stress in transformation induced by metal mixture.
Topics: Acetylcysteine; Air Pollutants; Animals; Arsenic; BALB 3T3 Cells; Cadmium; Carcinogens, Environmental; Cell Survival; Cell Transformation, Neoplastic; Free Radical Scavengers; Humans; Lead; Mice; Oxidative Stress; Reactive Oxygen Species | 2011 |
Characterizing N-acetylcysteine (NAC) and N-acetylcysteine amide (NACA) binding for lead poisoning treatment.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Free Radical Scavengers; Lead; Lead Poisoning; Photoelectron Spectroscopy; Spectrometry, Mass, Electrospray Ionization | 2012 |
Reversal of lead-induced toxicity due to the effect of antioxidants.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Brain; Cholesterol; Glutathione; Injections, Intraperitoneal; Kidney; Lead; Lead Poisoning; Liver; Male; Organometallic Compounds; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Uric Acid | 2013 |
Toxic effects of lead exposure in rats: involvement of oxidative stress, genotoxic effect, and the beneficial role of N-acetylcysteine supplemented with selenium.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Injections, Intraperitoneal; Lead; Lipid Peroxidation; Male; Malondialdehyde; Models, Animal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Selenium | 2014 |
TRPC1 is involved in Ca²⁺ influx and cytotoxicity following Pb²⁺ exposure in human embryonic kidney cells.
Topics: Acetylcysteine; Apoptosis; Blotting, Western; Calcium; Calcium Signaling; Cell Survival; HEK293 Cells; Humans; Indicators and Reagents; Lead; Lead Poisoning; Mass Spectrometry; Membrane Proteins; Neoplasm Proteins; Stromal Interaction Molecule 1; Transfection; TRPC Cation Channels | 2014 |
Lead Intoxication Synergies of the Ethanol-Induced Toxic Responses in Neuronal Cells--PC12.
Topics: Acetylcysteine; Animals; Apoptosis; Calcium Signaling; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Gene Expression Regulation; Glutathione; Lead; Lipid Peroxidation; Membrane Potential, Mitochondrial; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Protein Transport; Rats; Reactive Oxygen Species | 2015 |
The cytotoxic effect of the NOS-mediated oxidative stress in MCF-7 cells after PbCl₂ exposure.
Topics: Acetylcysteine; Arginine; Cell Survival; Environmental Pollutants; Eukaryotic Initiation Factor-2; Humans; Lead; MCF-7 Cells; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2016 |
Similarities between N-Acetylcysteine and Glutathione in Binding to Lead(II) Ions.
Topics: Acetylcysteine; Binding Sites; Coordination Complexes; Glutathione; Lead; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrometry, Mass, Electrospray Ionization | 2015 |
Genistein alleviates lead-induced neurotoxicity in vitro and in vivo: Involvement of multiple signaling pathways.
Topics: Acetylcysteine; Animals; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Genistein; In Situ Nick-End Labeling; Lead; Male; Maze Learning; Mitogen-Activated Protein Kinase Kinases; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; PC12 Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Spatial Memory; Superoxide Dismutase | 2016 |
Lead-induced DNA damage and cell apoptosis in human renal proximal tubular epithelial cell: Attenuation via N-acetyl cysteine and tannic acid.
Topics: Acetylcysteine; Apoptosis; DNA Damage; Epithelial Cells; Humans; Kidney Tubules, Proximal; Lead; Tannins | 2018 |
Protecting Effects of N-acetyl Cysteine Supplementation Against Lead and Cadmium-Induced Brain Toxicity in Rat Models.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Cadmium; Dietary Supplements; Lead; Male; Metals, Heavy; Oxidative Stress; Rats | 2022 |
Effects of N-Acetylcysteine Supplementation on Oxidative Stress and Expression of Apoptosis-Related Genes in Testicular Tissue of Rats Exposed to Lead.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Dietary Supplements; Lead; Male; Oxidative Stress; Rats; Semen; Spermatozoa; Testis | 2023 |
Health risk associated with heavy metal contamination of vegetables grown in agricultural soil of Siran valley, Mansehra, Pakistan-a case study.
Topics: Acetylcysteine; Cadmium; Environmental Monitoring; Lead; Metals, Heavy; Pakistan; Soil; Soil Pollutants; Vegetables | 2022 |
Anti-apoptotic properties of N-Acetyl cysteine and its effects on of Liver X receptor and Sirtuin 1 expression in the liver of rats exposed to Lead.
Topics: Acetylcysteine; Animals; bcl-2-Associated X Protein; Caspase 3; Lead; Lipids; Liver; Liver X Receptors; Rats; Sirtuin 1 | 2022 |