acetylcysteine and interleukin-8

acetylcysteine has been researched along with interleukin-8 in 94 studies

Research

Studies (94)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	20 (21.28)	18.2507
2000's	44 (46.81)	29.6817
2010's	27 (28.72)	24.3611
2020's	3 (3.19)	2.80

Authors

Authors	Studies
Ida, N; Maeda, K; Miyazaki, T; Murata, Y; Nagaya, T; Sato, M; Seo, H	1
Alfranca, A; Aragonés, J; Castellanos, MC; de Landázuri, MO; Muñoz, C; Pascual-Salcedo, D; Redondo, JM; Vara, A	1
Hirata, H; Kamata, H; Takeshita, H; Tanaka, C; Yagisawa, H	1
Ishii, Y; Kitamura, S; Yamasawa, H	1
Ahrens, P; Buehring, I; Friedrich, B; Schaaf, J; Schmidt, H; Zielen, S	1
Corriveau, CC; Danner, RL; Madara, PJ; Tropea, MM; Van Dervort, AL; Wesley, RA	1
Choi, AM; Jacoby, DB; Knobil, K; Weigand, GW	1
Hunninghake, GW; Mastronarde, JG; Matsushima, K; Monick, MM; Mukaida, N	1
Ichian, H; Muranaka, H; Nishimura, J; Okamoto, T; Sato, K; Sugamori, T; Takahashi, T; Tomoshima, Y	1
Chignell, CF; Hayden, PJ; Lange, RW; Luster, MI	1
Demanet, C; Huyghens, L; Spapen, H; Vincent, JL; Vleminckx, W; Zhang, H	1
Gon, Y; Hashimoto, S; Horie, T; Matsumoto, K; Nakayama, T; Takizawa, H	1
Kobzik, L; Stringer, B	1
Britigan, BE; Cox, CD; Denning, GM; Railsback, MA; Stoll, LL; Wollenweber, LA	1
Biagioli, MC; Kaul, P; Singh, I; Turner, RB	1
Hiraishi, H; Shimada, T; Terano, A; Watanabe, N	1
Desaki, M; Kasama, T; Kawasaki, S; Kobayashi, K; Kohyama, T; Kudoh, S; Matsushima, K; Nakahara, K; Ohtoshi, T; Takizawa, H; Yamamoto, K	1
Bone-Larson, CL; Colletti, LM; Hogaboam, CM; Kunkel, SL; Lukacs, NW; Simpson, KJ; Steinhauser, ML; Strieter, RM	1
Fourneau, C; Gosset, P; Tonnel, AB; Wallaert, B	1
Koizumi, H; Mano, K; Murata, M; Ohta, K; Yamashita, N	1
Gon, Y; Hashimoto, S; Horie, T; Jibiki, I; Kudoh, S; Matsumoto, K; Takeshita, I; Takizawa, H	1
Abe, S; Kudoh, S; Sugawara, I; Takizawa, H	1
Benítez, S; Caveda, L; De Castellarnau, C; Ordóñez-Llanos, J; Rosa, R; Sánchez-Quesada, JL; Vila, L	1
Chen, MZ; Chen, RF; Hsu, TY; Liu, HC; Shaio, MF; Teng, RJ; Yang, KD; Yang, MY	1
Gon, Y; Hashimoto, S; Horie, T; Matsumoto, K; Takeshita, I	1
Gon, Y; Hashimoto, S; Horie, T; Koura, T; Matsumoto, K; Nakayama, T; Takeshita, I	1
Desaki, M; Kasama, T; Kawasaki, S; Kobayashi, K; Nakahara, K; Ohtoshi, T; Okazaki, H; Sagai, M; Takami, K; Takizawa, H; Tanaka, M; Yamamoto, K	1
Chang, MM; Harper, R; Pan, R; Reddy, SP; Wu, K; Wu, R; Yoneda, K	1
Darville, TL; Farrar, HC; Givens, TG; Hinson, JA; James, LP; Kearns, GL; Simpson, PM; Sullivan, JE; Wasserman, GS	1
Antonicelli, F; Donaldson, K; Drost, EM; Hirani, N; MacNee, W; Parmentier, M; Rahman, I	1
Behr, J; Degenkolb, B; Krombach, F; Vogelmeier, C	1
Kohama, T; Koishi, R; Serizawa, N; Yoshimura, C	1
Lin, WW; Wen, HC; Wu, HM	1
Chi, KH; Lin, WW; Wu, HM	1
Kim, H; Kim, KH; Seo, JY	1
Lappas, M; Permezel, M; Rice, GE	1
Barve, SS; Butt, W; Joshi-Barve, S; Klein, J; McClain, CJ	1
Galley, HF; Paterson, RL; Webster, NR	1
Desaki, M; Kawasaki, S; Kohyama, T; Okazaki, H; Takizawa, H; Yamamoto, K; Yamauchi, Y	1
Demedts, MG; Dupont, LJ; Van Raemdonck, DE; Vanaudenaerde, BM; Verleden, GM; Wuyts, WA	1
Hales, CA; Jafari, B; Li, LF; Ouyang, B; Quinn, DA	1
Baue, AE	1
Antonicelli, F; Brown, D; Donaldson, K; Drost, EM; Hirani, N; MacNee, W; Parmentier, M; Rahman, I	1
Abdalla, DS; Ferreira, SI; Luis, MC; Masokawa, IY; Reis, M; Spada, C; Treitinger, A; Van Der Sander Silveira, M; Verdi, JC	1
Kawasaki, T; Nandate, K; Ogata, M; Sata, T; Shigematsu, A; Tamura, H	1
Bernhard, D; Csordas, A; Henderson, B; Kind, M; Rossmann, A; Wick, G	1
Cheng, YW; Kang, JJ; Lee, CC	1
de Backer, WA; Demkow, U; Górecka, D; van Overveld, FJ; Zielinski, J	1
De Backer, WA; Heytens, E; Manuel-y-Keenoy, B; Radomska-Lesniewska, D; Sadowska, AM; Schippers, G; Vertongen, T	1
Bole-Feysot, C; Coëffier, M; Déchelotte, P; Ducrotté, P; Hubert-Buron, A; Leblond, J	1
De Backer, WA; Demkow, U; Radomska-Leśniewska, DM; Sadowska, AM; Van Overveld, FJ; Zieliński, J	1
Jiang, XF; Xu, AQ; Xu, ZH; Yang, KX; Zeng, WY	1
Akimaru, K; Hirota, R; Nakamura, H	1
Borkin, MS; Boyd, SL; Koepke, JI; Terlecky, LJ; Terlecky, SR; Young, CN	1
Arriaza, E; Castillejo, MS; Delgado, M; Gisbert, JP; Gonzalez Lara, V; Guijarro, LG; Marin-Jimenez, I; Mate, J; Olleros, T; Pena, AS; Perez-Calle, JL; Prieto-Merino, D	1
Jiang, XF; Liu, YM; Pu, J; Zeng, WY	1
Bartling, TR; Drumm, ML	2
Cisowski, J; Dulak, J; Jozkowicz, A; Kotlinowski, J; Mleczko, K; Taha, H; Was, H; Weigel, G	1
Arranz, L; De la Fuente, M; Fernández, C; Ribera, JM; Rodríguez, A	1
Civelli, M; Facchinetti, F; Moretto, N; Patacchini, R; Singh, D; Southworth, T	1
Bai, J; Bhattacharyya, A; Crowe, SE; Ernst, PB; Mifflin, RC; Mitra, S; O'Hara, AM	1
Akamatsu, K; Hirano, T; Ichikawa, T; Ichinose, M; Kanda, M; Koarai, A; Matsunaga, K; Minakata, Y; Sugiura, H; Tanaka, R; Yanagisawa, S	1
Akamatsu, K; Hirano, T; Ichikawa, T; Ichinose, M; Koarai, A; Matsunaga, K; Minakata, Y; Sugiura, H; Yanagisawa, S	1
Aulbach, B; Bargon, J; Dauletbaev, N; Fischer, P; Gross, J; Kusche, W; Thyroff-Friesinger, U; Wagner, TO	1
Arkadopoulos, N; Avgerinos, ED; Chondros, C; Kostopanagiotou, G; Markidou, E; Smyrniotis, V; Theodoraki, K; Voiniadis, P	1
Coma-Canella, I; Echeverria, A; Garcia-Fernandez, N; Páramo, JA; Sanchez-Ibarrola, A	1
Cortijo, J; Juan, G; Milara, J; Peiró, T; Serrano, A	1
Zhang, CL; Zhang, H	1
Choi, SY; Kim, H; Kim, JM; Kuwano, K; Lim, JW; Shimizu, T	1
Akiyama, S; Furukawa, T; Haraguchi, M; Ikeda, R; Kuramoto, T; Nishioka, Y; Sone, S; Tabata, S; Takeda, Y; Yamada, K; Yamamoto, M	1
Adhami, K; Ding, W; Gordon, JS; Granstein, RD; Lee, J; Levin, L; Moquete, R; Perez, E; Schierl, M; Stock, MB; Stohl, LL; Wong, J; Zhou, XK	1
Fu, X; Hirche, C; Lehnhardt, M; Sun, J; Wang, R; Xia, Y; Xiong, L; Yang, J; Yang, Y	1
Jiang, H; Yin, G; Zhang, C; Zhang, H	1
Evans, TW; Griffiths, MJ; Mumby, S; Quinlan, GJ; Ramakrishnan, L	1
Bailey, KL; DeVasure, JM; Heires, AJ; Nordgren, TM; Poole, JA; Romberger, DJ; Wyatt, TA	1
Chung, KC; Kim, H; Ko, JW; Lim, JW; Lim, SY	1
Feltis, BN; Lopata, AL; Saptarshi, SR; Wright, PF	1
Jiménez-Vélez, BD; Ortiz-Martínez, MG; Rodríguez-Cotto, RI	1
Beaupere, C; Capeau, J; Fève, B; Garcia, M; Lagathu, C; Larghero, J	1
Jeong, KY; Kim, CR; Kim, HP; Kim, TY; Yi, MH; Yong, TS	1
Jiang, N; Li, J; Wang, J; Wu, W; Yan, Z; Yang, W; Yao, W; Zhang, R	1
Balszuweit, F; Kehe, K; Menacher, G; Popp, T; Schmidt, A; Steinritz, D; Thiermann, H; Worek, F	1
Pathak, S; Stern, C; Vambutas, A	1
Christmas, SE; Hammad, A; Kumar, A; Shalmanova, L	1
Fang, Y; Jia, YP; Li, Q; Mao, XH; Tang, B; Wang, K; Zeng, DZ; Zhang, ZJ; Zhu, P	1
Khan, N; Matsuyama, T; Motomura, E; Muniroh, M; Vogel, CF; Yamamoto, M; Yanagisawa, R	1
Bellon, H; Heigl, T; Hoet, P; Lammertyn, E; Mathyssen, C; Pilette, C; Sacreas, A; Vanaudenaerde, BM; Vandermeulen, E; Verleden, GM; Verleden, SE; Vos, R; Vriens, H	1
Cen, LJ; Chen, L; Li, CC; Li, X; Meng, FH; Wen, YH; Yang, CT; Zhang, H	1
Aldridge, K; Bowden, A; Dosanjh, D; Foronjy, R; Grudzinska, FS; Lewis, KE; Lugg, ST; Mahida, RY; Naidu, B; Parekh, D; Sapey, E; Scott, A; Thickett, DR	1
Chen, C; Hei, Z; Li, X; Liu, D; Wei, X; Yao, W; Zhang, Z	1
Atlan, M; Béréziat, V; Bourgeois, C; Capeau, J; Desjardins, D; Ejlalmanesh, T; Fève, B; Gorwood, J; Lagathu, C; Lambotte, O; Le Grand, R; Mantecon, M; Rose, C	1
Kaufman, G; Skrtic, D	1
Alvarez, M; Andueza, MP; Berraondo, P; Cirella, A; Garasa, S; Glez-Vaz, J; Melero, I; Migueliz, I; Ochoa, MDC; Olivera, I; Perez Gracia, JL; Rodríguez-Ruiz, ME; Rouzaut, A; Sanmamed, MF; Teijeira, A	1

Trials

11 trial(s) available for acetylcysteine and interleukin-8

Article	Year
Chronic sinusitis refractory to standard management in patients with humoral immunodeficiencies. Clinical and experimental immunology, 1997, Volume: 109, Issue:3 Topics: Acetylcysteine; Administration, Intranasal; Adolescent; Adult; Agammaglobulinemia; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antiviral Agents; Ataxia Telangiectasia; Azithromycin; Beclomethasone; Blood Proteins; Child; Child, Preschool; Chronic Disease; Common Variable Immunodeficiency; Eosinophil Granule Proteins; Ethmoid Sinusitis; Female; Frontal Sinusitis; Glucocorticoids; Humans; Immunization, Passive; Interleukin-8; Lymphoproliferative Disorders; Magnetic Resonance Imaging; Male; Nasal Lavage Fluid; Paranasal Sinuses; Radiography; Ribonucleases; Sinusitis; Tumor Necrosis Factor-alpha	1997
Does N-acetyl-L-cysteine influence cytokine response during early human septic shock? Chest, 1998, Volume: 113, Issue:6 Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antigens, CD; Double-Blind Method; Female; Hemodynamics; Humans; Infusions, Intravenous; Interleukin-10; Interleukin-6; Interleukin-8; Interleukins; Lactic Acid; Lung Compliance; Male; Middle Aged; Oxygen Consumption; Prospective Studies; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Shock, Septic; Tumor Necrosis Factor-alpha	1998
Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: effects of N-acetylcysteine. The European respiratory journal, 2002, Volume: 19, Issue:5 Topics: Acetylcysteine; Administration, Oral; Adult; Bronchoalveolar Lavage Fluid; Female; Free Radical Scavengers; Glutathione; Humans; Interleukin-8; Male; Middle Aged; Oxidative Stress; Peroxidase; Prospective Studies; Pulmonary Fibrosis	2002
The effect of N-acetylcysteine on nuclear factor-kappa B activation, interleukin-6, interleukin-8, and intercellular adhesion molecule-1 expression in patients with sepsis. Critical care medicine, 2003, Volume: 31, Issue:11 Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Free Radical Scavengers; Humans; Infusions, Intravenous; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Male; Middle Aged; NF-kappa B; Sepsis	2003
Effect of N-acetyl-L-cysteine on lymphocyte apoptosis, lymphocyte viability, TNF-alpha and IL-8 in HIV-infected patients undergoing anti-retroviral treatment. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2004, Volume: 8, Issue:5 Topics: Acetylcysteine; Administration, Oral; Adult; Anti-HIV Agents; Apoptosis; CD4 Lymphocyte Count; Cysteine; Double-Blind Method; Glutathione; HIV Infections; Humans; Interleukin-8; Lymphocytes; Middle Aged; Time Factors; Tumor Necrosis Factor-alpha; Viral Load	2004
New developments in the treatment of COPD: comparing the effects of inhaled corticosteroids and N-acetylcysteine. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56 Suppl 4 Topics: Acetylcysteine; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Androstadienes; Anti-Inflammatory Agents; Antioxidants; Double-Blind Method; Eosinophil Cationic Protein; Expectorants; Female; Fluticasone; Forced Expiratory Volume; Glutathione Peroxidase; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Male; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Sputum; Treatment Outcome	2005
Effect of N-acetylcysteine on neutrophil activation markers in healthy volunteers: in vivo and in vitro study. Pharmacological research, 2006, Volume: 53, Issue:3 Topics: Acetylcysteine; Adult; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Interleukin-8; Male; Middle Aged; Neutrophil Activation; Neutrophils; NF-kappa B; Pancreatic Elastase; Respiratory Burst; Time Factors	2006
N-acetyl-L-cysteine combined with mesalamine in the treatment of ulcerative colitis: randomized, placebo-controlled pilot study. World journal of gastroenterology, 2008, May-14, Volume: 14, Issue:18 Topics: Acetylcysteine; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL2; Colitis, Ulcerative; Drug Therapy, Combination; Female; Free Radical Scavengers; Glutathione; Humans; Interleukin-6; Interleukin-8; Male; Mesalamine; Middle Aged; Pilot Projects; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha	2008
A phase II study on safety and efficacy of high-dose N-acetylcysteine in patients with cystic fibrosis. European journal of medical research, 2009, Aug-12, Volume: 14, Issue:8 Topics: Acetylcysteine; Adult; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Free Radical Scavengers; Glutathione; Humans; Interleukin-8; Male; Sputum; Tumor Necrosis Factor-alpha; Young Adult	2009
Randomized clinical trial on acute effects of i.v. iron sucrose during haemodialysis. Nephrology (Carlton, Vic.), 2010, Volume: 15, Issue:2 Topics: Acetylcysteine; Aged; Antioxidants; Biomarkers; CD11b Antigen; CD18 Antigens; Cross-Over Studies; Endothelium, Vascular; Female; Ferric Compounds; Ferric Oxide, Saccharated; Glucaric Acid; Hematinics; Humans; Inflammation; Inflammation Mediators; Infusions, Intravenous; Intercellular Adhesion Molecule-1; Interleukin-8; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Prospective Studies; Renal Dialysis; Time Factors; Treatment Outcome; von Willebrand Factor	2010
Bioscience reports, 2018, 10-31, Volume: 38, Issue:5 Topics: Acetylcysteine; Administration, Inhalation; Breath Tests; Exhalation; Female; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Liver Transplantation; Lung; Lung Diseases; Male; Middle Aged; Oxidative Stress; Postoperative Complications; Tumor Necrosis Factor-alpha; Uteroglobin	2018

Other Studies

83 other study(ies) available for acetylcysteine and interleukin-8

Article	Year
Antioxidants inhibit tumor necrosis factor-alpha mediated stimulation of interleukin-8, monocyte chemoattractant protein-1, and collagenase expression in cultured human synovial cells. The Journal of rheumatology, 1996, Volume: 23, Issue:3 Topics: Acetylcysteine; Antioxidants; Arthritis, Rheumatoid; Cells, Cultured; Chemokine CCL2; Collagenases; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Interleukin-8; NF-kappa B; Pyrrolidonecarboxylic Acid; RNA, Messenger; Synovial Membrane; Thiazoles; Thiazolidines; Transcription, Genetic; Tumor Necrosis Factor-alpha	1996
Pyrrolidine dithiocarbamate inhibits the production of interleukin-6, interleukin-8, and granulocyte-macrophage colony-stimulating factor by human endothelial cells in response to inflammatory mediators: modulation of NF-kappa B and AP-1 transcription fac Blood, 1996, Nov-01, Volume: 88, Issue:9 Topics: Acetylcysteine; Antioxidants; Cells, Cultured; Endothelium, Vascular; Free Radical Scavengers; Gene Expression Regulation; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; NF-kappa B; Pyrrolidines; Thiocarbamates; Transcription Factor AP-1	1996
Redox regulation of lipopolysaccharide (LPS)-induced interleukin-8 (IL-8) gene expression mediated by NF kappa B and AP-1 in human astrocytoma U373 cells. Biochemical and biophysical research communications, 1997, Mar-17, Volume: 232, Issue:2 Topics: Acetylcysteine; Antioxidants; Astrocytoma; Buthionine Sulfoximine; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Lipopolysaccharides; NF-kappa B; Oxidation-Reduction; Transcription Factor AP-1; Tumor Cells, Cultured	1997
[Role of oxidants in adhesion molecule expression and cytokine production]. Nihon Kyobu Shikkan Gakkai zasshi, 1996, Volume: 34 Suppl Topics: Acetylcysteine; Animals; Antioxidants; Bronchi; Cells, Cultured; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Lung Diseases; Rats; Reactive Oxygen Species; Tumor Necrosis Factor-alpha	1996
Effects of nitric oxide on chemotaxis and endotoxin-induced interleukin-8 production in human neutrophils. The Journal of infectious diseases, 1998, Volume: 177, Issue:1 Topics: Acetylcysteine; Cells, Cultured; Chemotaxis; Complement C5a; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Ferricyanides; Glutathione; Humans; Interleukin-8; Leukotriene B4; Lipopolysaccharides; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Nitroso Compounds; omega-N-Methylarginine; RNA, Messenger; S-Nitrosoglutathione; Up-Regulation	1998
Role of oxidants in influenza virus-induced gene expression. The American journal of physiology, 1998, Volume: 274, Issue:1 Topics: Acetylcysteine; Animals; Base Sequence; Binding Sites; Chick Embryo; Epithelial Cells; Gene Expression Regulation; Humans; Influenza A virus; Interleukin-8; Lung Neoplasms; NF-kappa B; Nuclear Proteins; Oligodeoxyribonucleotides; Reactive Oxygen Species; RNA, Messenger; Sp1 Transcription Factor; Superoxide Dismutase; Transcription, Genetic; Tumor Cells, Cultured	1998
Activator protein-1 is the preferred transcription factor for cooperative interaction with nuclear factor-kappaB in respiratory syncytial virus-induced interleukin-8 gene expression in airway epithelium. The Journal of infectious diseases, 1998, Volume: 177, Issue:5 Topics: Acetylcysteine; Antioxidants; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cyclic N-Oxides; Dimethyl Sulfoxide; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Lung Neoplasms; NF-kappa B; Recombinant Proteins; Respiratory Syncytial Viruses; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured	1998
[Effects of erythromycin on Pseudomonas aeruginosa pyocyanine-induced IL-8 production and its biological activity (the 2nd report)]. The Japanese journal of antibiotics, 1998, Volume: 51 Suppl A Topics: Acetylcysteine; Anti-Bacterial Agents; Cells, Cultured; Dimethyl Sulfoxide; Erythromycin; Humans; Interleukin-8; Macrophages, Alveolar; Pseudomonas aeruginosa; Pyocyanine; Superoxide Dismutase	1998
Anthralin stimulates keratinocyte-derived proinflammatory cytokines via generation of reactive oxygen species. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:4 Topics: Acetylcysteine; Administration, Topical; Anthralin; Anti-Inflammatory Agents; Antibodies; Antioxidants; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Keratinocytes; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Thiourea; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Vitamin E	1998
N-acetylcysteine inhibits IL-1 alpha-induced IL-8 secretion by bronchial epithelial cells. Respiratory medicine, 1998, Volume: 92, Issue:3 Topics: Acetylcysteine; Antioxidants; Bronchi; Butylated Hydroxyanisole; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Free Radical Scavengers; Humans; Interleukin-1; Interleukin-8; Pyrrolidines; Thiocarbamates	1998
Environmental particulate-mediated cytokine production in lung epithelial cells (A549): role of preexisting inflammation and oxidant stress. Journal of toxicology and environmental health. Part A, 1998, Sep-11, Volume: 55, Issue:1 Topics: Acetylcysteine; Adenocarcinoma, Bronchiolo-Alveolar; Air Pollution; Antioxidants; Carbon; Chromans; Coal Ash; Dose-Response Relationship, Drug; Epithelial Cells; Flow Cytometry; Fluoresceins; Free Radical Scavengers; Humans; Industrial Waste; Interleukin-8; Lung; Lung Neoplasms; Oxidative Stress; Particle Size; Particulate Matter; Petroleum; Piperazines; Pneumonia; Quartz; Titanium; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1998
Pseudomonas pyocyanin increases interleukin-8 expression by human airway epithelial cells. Infection and immunity, 1998, Volume: 66, Issue:12 Topics: Acetylcysteine; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chemokine CCL5; Drug Synergism; Epithelial Cells; Humans; Interleukin-8; Lung; Oxidants; Protein Kinase C; Protein-Tyrosine Kinases; Pseudomonas; Pyocyanine; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha	1998
The role of oxidative stress in rhinovirus induced elaboration of IL-8 by respiratory epithelial cells. Free radical biology & medicine, 1999, Volume: 26, Issue:3-4 Topics: Acetylcysteine; Cell Line; Epithelial Cells; Humans; Hydrogen Peroxide; Interleukin-8; Lung; NF-kappa B; Oxidative Stress; Rhinovirus; Signal Transduction; Stimulation, Chemical	1999
Redox regulation of interleukin-8 expression in MKN28 cells. Digestive diseases and sciences, 1999, Volume: 44, Issue:2 Topics: Acetylcysteine; Blotting, Northern; Dimethyl Sulfoxide; Electrophoresis; Enzyme-Linked Immunosorbent Assay; Gastric Mucosa; Humans; Hydrogen Peroxide; Interleukin-1; Interleukin-8; NF-kappa B; Oxidation-Reduction; Reactive Oxygen Species; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1999
Diesel exhaust particles induce NF-kappa B activation in human bronchial epithelial cells in vitro: importance in cytokine transcription. Journal of immunology (Baltimore, Md. : 1950), 1999, Apr-15, Volume: 162, Issue:8 Topics: Acetylcysteine; Antioxidants; Blotting, Northern; Bronchi; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Gene Expression Regulation; Humans; Interleukin-8; NF-kappa B; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription, Genetic; Vehicle Emissions	1999
Novel CXCR2-dependent liver regenerative qualities of ELR-containing CXC chemokines. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:12 Topics: Acetaminophen; Acetylcysteine; Animals; Aspartate Aminotransferases; Cell Division; Cells, Cultured; Chemokine CXCL2; Chemokine CXCL5; Chemokines, CXC; Chemotactic Factors; Female; Hepatocyte Growth Factor; Interleukin-8; Liver; Liver Regeneration; Mice; Monokines; Receptors, Chemokine; Receptors, Interleukin; Receptors, Interleukin-8B	1999
Thiol regulation of the production of TNF-alpha, IL-6 and IL-8 by human alveolar macrophages. The European respiratory journal, 1999, Volume: 14, Issue:1 Topics: Acetylcysteine; Adult; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Cells, Cultured; DNA Primers; Female; Glutathione; Humans; Interleukin-6; Interleukin-8; Intracellular Fluid; Lipopolysaccharides; Macrophages, Alveolar; Male; Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha	1999
Nuclear factor kappa B mediates interleukin-8 production in eosinophils. International archives of allergy and immunology, 1999, Volume: 120, Issue:3 Topics: Acetylcysteine; Cell Nucleus; Cysteine Proteinase Inhibitors; Densitometry; Electrophoresis; Enzyme-Linked Immunosorbent Assay; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunohistochemistry; Immunosuppressive Agents; Interleukin-8; Leupeptins; NF-kappa B; Tacrolimus; Tumor Necrosis Factor-alpha	1999
Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation. American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:1 Topics: Acetylcysteine; Blotting, Western; Bronchi; Cells, Cultured; Chemokine CCL5; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Threonine; Tyrosine; Vehicle Emissions	2000
Diesel exhaust (DE)-induced cytokine expression in human bronchial epithelial cells: a study with a new cell exposure system to freshly generated DE in vitro. American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:3 Topics: Acetylcysteine; Antioxidants; Bronchi; Cell Line, Transformed; Epithelial Cells; Free Radical Scavengers; Gene Expression; Humans; In Vitro Techniques; Interleukin-8; Pyrrolidines; RNA, Messenger; Thiocarbamates; Thymidine; Transforming Growth Factor beta; Tritium; Vehicle Emissions	2000
Electronegative LDL from normolipemic subjects induces IL-8 and monocyte chemotactic protein secretion by human endothelial cells. Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:10 Topics: Acetylcysteine; Adult; Antioxidants; Cells, Cultured; Chemokine CCL2; Chromatography, Ion Exchange; Dactinomycin; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Female; Free Radical Scavengers; Humans; Interleukin-8; Lipoproteins, LDL; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Thiobarbiturates; Tumor Necrosis Factor-alpha	2000
A model to study antioxidant regulation of endotoxemia-modulated neonatal granulopoiesis and granulocyte apoptosis. Pediatric research, 2000, Volume: 48, Issue:6 Topics: Acetylcysteine; Adult; Antioxidants; Apoptosis; Cells, Cultured; DNA Fragmentation; Endotoxemia; Endotoxins; Fetal Blood; Granulocytes; Hematopoiesis; Humans; Infant, Newborn; Interleukin-8; Oxidative Stress; Reactive Oxygen Species; Tumor Necrosis Factor-alpha	2000
N-acetylcysteine attenuates TNF-alpha-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells. British journal of pharmacology, 2001, Volume: 132, Issue:1 Topics: Acetylcysteine; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Glutathione; Humans; Hydrogen Peroxide; Interleukin-8; MAP Kinase Kinase 3; MAP Kinase Kinase 6; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pulmonary Artery; Tumor Necrosis Factor-alpha	2001
N-acetyl-L-cysteine inhibits bleomycin-induced interleukin-8 secretion by bronchial epithelial cells. Respirology (Carlton, Vic.), 2000, Volume: 5, Issue:4 Topics: Acetylcysteine; Antimetabolites, Antineoplastic; Antioxidants; Bleomycin; Bronchi; Cell Line; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Humans; Interleukin-8; Pyrrolidines; Respiratory Distress Syndrome; Respiratory Mucosa; Thiocarbamates	2000
Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial cells. American journal of respiratory cell and molecular biology, 2001, Volume: 24, Issue:4 Topics: Acetylcysteine; Antioxidants; Benzene; Bronchi; Cell Line; Chemokine CCL5; Enzyme Inhibitors; Epithelial Cells; Free Radical Scavengers; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; In Vitro Techniques; Interleukin-8; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrrolidines; RNA, Messenger; T-Lymphocytes; Thiocarbamates; Vehicle Emissions	2001
Activation of nuclear factor-kappa b transcriptional activity in airway epithelial cells by thioredoxin but not by N-acetyl-cysteine and glutathione. American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:2 Topics: Acetylcysteine; Bronchi; Cell Line; Cell Nucleus; Cells, Cultured; DNA; Epithelial Cells; Gene Expression; Glutathione; Humans; Interleukin-8; NF-kappa B; Oxidation-Reduction; Thioredoxins; Trachea; Transcription, Genetic; Tumor Necrosis Factor-alpha	2001
Elevation of serum interleukin 8 levels in acetaminophen overdose in children and adolescents. Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:3 Topics: Acetaminophen; Acetylcysteine; Adolescent; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Overdose; Female; Humans; Infant; Interleukin-8; Liver Function Tests; Male; Prothrombin Time	2001
Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells. Free radical biology & medicine, 2002, Mar-15, Volume: 32, Issue:6 Topics: Acetylcysteine; Binding Sites; Cell Line; Chemotaxis; Epithelial Cells; Humans; Hydrogen Peroxide; Interleukin-8; Lysine; NF-kappa B; Oxidants; Oxidation-Reduction; Pulmonary Alveoli; RNA, Messenger; Tumor Necrosis Factor-alpha	2002
Leustroducsin B activates nuclear factor-kappaB via the acidic sphingomyelinase pathway in human bone marrow-derived stromal cell line KM-102. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2002, Volume: 22, Issue:3 Topics: Acetylcysteine; Antioxidants; Bone Marrow Cells; Bridged-Ring Compounds; Cell Line; Clone Cells; Desipramine; Genes, Reporter; Humans; Interleukin-11; Interleukin-8; Lactones; Mutagenesis, Site-Directed; NF-kappa B; Norbornanes; Organophosphorus Compounds; Perhexiline; Phosphodiesterase Inhibitors; Point Mutation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Pyrones; Signal Transduction; Sphingomyelin Phosphodiesterase; Stromal Cells; Thiocarbamates; Thiones; Transcriptional Activation	2002
Proteasome inhibitors stimulate interleukin-8 expression via Ras and apoptosis signal-regulating kinase-dependent extracellular signal-related kinase and c-Jun N-terminal kinase activation. American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:2 Topics: Acetylcysteine; Cell Line; Chemotaxis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Epithelial Cells; Genes, Reporter; Humans; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Leupeptins; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neutrophils; NF-kappa B; Proteasome Endopeptidase Complex; ras Proteins; Reactive Oxygen Species; Transcription Factor AP-1; Transcription Factors; Tumor Cells, Cultured	2002
Proteasome inhibitors stimulate activator protein-1 pathway via reactive oxygen species production. FEBS letters, 2002, Aug-28, Volume: 526, Issue:1-3 Topics: Acetylcysteine; Antioxidants; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Gene Expression Regulation; Genes, Reporter; Humans; Interleukin-8; Leupeptins; Luciferases; Multienzyme Complexes; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Reactive Oxygen Species; Recombinant Proteins; Transcription Factor AP-1; Transfection	2002
Transcriptional regulation by thiol compounds in Helicobacter pylori-induced interleukin-8 production in human gastric epithelial cells. Annals of the New York Academy of Sciences, 2002, Volume: 973 Topics: Acetylcysteine; Adenocarcinoma; Gastric Mucosa; Gene Expression Regulation; Glutathione; Helicobacter pylori; Humans; Interleukin-8; Reactive Oxygen Species; Stomach Neoplasms; Sulfhydryl Compounds; Superoxide Dismutase; Transcription, Genetic; Tumor Cells, Cultured	2002
N-Acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in vitro. The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:4 Topics: Acetylcysteine; Amnion; Chorion; Culture Techniques; Cytokines; Decidua; Dinoprost; DNA; Endopeptidases; Extraembryonic Membranes; F2-Isoprostanes; Female; Humans; Interleukin-6; Interleukin-8; L-Lactate Dehydrogenase; Matrix Metalloproteinase 9; NF-kappa B; Oxidative Stress; Phospholipases A; Phospholipids; Pregnancy; Urokinase-Type Plasminogen Activator	2003
Inhibition of proteasome function leads to NF-kappaB-independent IL-8 expression in human hepatocytes. Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:5 Topics: Acetylcysteine; Apoptosis; Cell Death; Cell Line, Tumor; Chemotaxis, Leukocyte; Cysteine Proteinase Inhibitors; DNA; DNA Fragmentation; Enzyme Activation; Fetus; Hepatocytes; Humans; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Leupeptins; Mitogen-Activated Protein Kinases; Neutrophils; NF-kappa B; Peptide Hydrolases; Proteasome Endopeptidase Complex; RNA, Messenger; Transcription Factor AP-1; Up-Regulation	2003
Methotrexate induces interleukin-8 production by human bronchial and alveolar epithelial cells. Clinical science (London, England : 1979), 2004, Volume: 106, Issue:6 Topics: Acetylcysteine; Bronchi; Cell Line; Cycloheximide; Epithelial Cells; Folic Acid Antagonists; Free Radical Scavengers; Glucose; Humans; Hypoglycemia; Interleukin-1; Interleukin-8; Lipopolysaccharides; Methotrexate; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Pulmonary Alveoli; Threonine; Tumor Necrosis Factor-alpha; Tyrosine	2004
N-acetylcysteine inhibits interleukin-17-induced interleukin-8 production from human airway smooth muscle cells: a possible role for anti-oxidative treatment in chronic lung rejection? The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2004, Volume: 23, Issue:1 Topics: Acetylcysteine; Bronchi; Cells, Cultured; Free Radical Scavengers; Graft Rejection; Humans; Interleukin-17; Interleukin-8; Isoprostanes; Lung Transplantation; Myocytes, Smooth Muscle; Reactive Oxygen Species	2004
Intracellular glutathione in stretch-induced cytokine release from alveolar type-2 like cells. Respirology (Carlton, Vic.), 2004, Volume: 9, Issue:1 Topics: Acetylcysteine; Antioxidants; Blotting, Northern; Buthionine Sulfoximine; Cells, Cultured; Cytokines; Epithelial Cells; Glutathione; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Isoprostanes; Lipid Peroxidation; NF-kappa B; Oxidative Stress; Pulmonary Alveoli; Respiratory Distress Syndrome; Stress, Mechanical; Transcription Factor AP-1	2004
When will we learn? Critical care medicine, 2004, Volume: 32, Issue:4 Topics: Acetylcysteine; Critical Care; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Multiple Organ Failure; NF-kappa B; Randomized Controlled Trials as Topic; Systemic Inflammatory Response Syndrome; Treatment Failure	2004
Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn. American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 286, Issue:6 Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Chemotaxis; Cycloheximide; Enzyme Inhibitors; Gene Expression; Humans; In Vitro Techniques; Interleukin-8; Lipopolysaccharides; Lysine; Male; Monocytes; Neutrophils; Okadaic Acid; Pneumonia; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Transcription Factors	2004
N-acetyl-cysteine attenuates endotoxin-induced adhesion molecule expression in human whole blood. Anesthesia and analgesia, 2005, Volume: 100, Issue:5 Topics: Acetylcysteine; CD11b Antigen; Cell Adhesion Molecules; Dose-Response Relationship, Drug; Endotoxins; Humans; Interleukin-8; L-Selectin; Leukocytes	2005
Cigarette smoke metal-catalyzed protein oxidation leads to vascular endothelial cell contraction by depolymerization of microtubules. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9 Topics: Acetylcysteine; Antioxidants; Atherosclerosis; Calcium; Catalysis; Cells, Cultured; Endothelial Cells; Humans; Interleukin-6; Interleukin-8; Metals; Microtubules; Nicotiana; Oxidative Stress; P-Selectin; Paclitaxel; Platelet Endothelial Cell Adhesion Molecule-1; Proteins; Smoke; Tubulin; Vasoconstriction	2005
Motorcycle exhaust particles induce IL-8 production through NF-kappaB activation in human airway epithelial cells. Journal of toxicology and environmental health. Part A, 2005, Volume: 68, Issue:17-18 Topics: Acetylcysteine; Anthracenes; Cell Line, Tumor; Cell Survival; Epithelial Cells; Flavonoids; Gene Expression Regulation; Humans; Interleukin-8; Motorcycles; NF-kappa B; Proline; RNA, Messenger; Thiocarbamates; Vehicle Emissions	2005
Regulation of proteolysis by cytokines in the human intestinal epithelial cell line HCT-8: role of IFNgamma. Biochimie, 2006, Volume: 88, Issue:7 Topics: Acetylcysteine; Blotting, Western; Cell Line, Tumor; Cytokines; Epithelial Cells; Gene Expression; Humans; Hydrolysis; Interferon-gamma; Interleukin-1; Interleukin-8; Intestinal Mucosa; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Ubiquitin; Ubiquitin C	2006
Influence of N-acetylcysteine on ICAM-1 expression and IL-8 release from endothelial and epithelial cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 4 Topics: Acetylcysteine; Anti-Inflammatory Agents; Antioxidants; Cell Line; Endothelial Cells; Epithelial Cells; Humans; Intercellular Adhesion Molecule-1; Interleukin-8	2006
[Effect of N-acetylcysteine on lipopolysaccharide induced preterm labor in mice]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2007, Volume: 38, Issue:2 Topics: Acetylcysteine; Animals; Female; Fetus; Gene Expression Regulation; Infections; Interleukin-8; Lipopolysaccharides; Mice; Obstetric Labor, Premature; Oxidation-Reduction; Pregnancy; RNA, Messenger; Transcription Factor RelA	2007
In vitro toxicity evaluation of diesel exhaust particles on human eosinophilic cell. Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:4 Topics: Acetylcysteine; Cell Movement; Chemokine CCL2; Chemotaxis; Clone Cells; Eosinophils; HL-60 Cells; Humans; Interleukin-8; Leupeptins; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Up-Regulation; Vehicle Emissions	2008
Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease. The Journal of investigative dermatology, 2008, Volume: 128, Issue:11 Topics: Acetylcysteine; Antioxidants; Catalase; Cells, Cultured; Free Radical Scavengers; Humans; Hydrogen Peroxide; I-kappa B Proteins; Interleukin-6; Interleukin-8; Keratinocytes; Male; Protein Kinases; Psoriasis; Reactive Oxygen Species; Signal Transduction; Sirolimus; Skin Diseases; Taurine; TOR Serine-Threonine Kinases; Transcription Factor RelA; Tumor Necrosis Factor-alpha	2008
[Effect of N-acetylcysteine on lipopolysaccharide stimulating IL-8 expression of human uterine smooth cell]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2008, Volume: 39, Issue:2 Topics: Acetylcysteine; Blotting, Western; Cells, Cultured; Female; Free Radical Scavengers; Gene Expression; Humans; Interleukin-8; Lipopolysaccharides; Myocytes, Smooth Muscle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor RelA; Uterus	2008
Oxidative stress causes IL8 promoter hyperacetylation in cystic fibrosis airway cell models. American journal of respiratory cell and molecular biology, 2009, Volume: 40, Issue:1 Topics: Acetylation; Acetylcysteine; Animals; Cell Line; Cystic Fibrosis; Cytokines; Epithelial Cells; Free Radical Scavengers; Humans; Hydrogen Peroxide; Interleukin-8; Oxidants; Oxidative Stress; Promoter Regions, Genetic; Respiratory Mucosa; Transcription, Genetic	2009
15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress. Antioxidants & redox signaling, 2008, Volume: 10, Issue:12 Topics: Acetylcysteine; Cells, Cultured; Colforsin; Cyclic AMP; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Ethacrynic Acid; Ethylmaleimide; Gene Expression; Hemin; Humans; Hydantoins; Interleukin-8; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Protein Kinase Inhibitors; Reactive Oxygen Species; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Superoxide Dismutase; Transfection; Xanthones	2008
The glutathione precursor N-acetylcysteine improves immune function in postmenopausal women. Free radical biology & medicine, 2008, Nov-01, Volume: 45, Issue:9 Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Case-Control Studies; Female; Glutathione; Humans; Immune System; Interleukin-2; Interleukin-8; Leukocytes; Middle Aged; Models, Biological; Tumor Necrosis Factor-alpha	2008
alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases. American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:5 Topics: Acetylcysteine; Aged; Aldehydes; Cell Survival; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Humans; Interleukin-8; Lung; Macrophages; Male; Mesna; Middle Aged; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Smoking	2009
Tumor necrosis factor (TNF)-alpha-induced IL-8 expression in gastric epithelial cells: role of reactive oxygen species and AP endonuclease-1/redox factor (Ref)-1. Cytokine, 2009, Volume: 46, Issue:3 Topics: Acetylcysteine; Cells, Cultured; DNA-(Apurinic or Apyrimidinic Site) Lyase; Epithelial Cells; Free Radical Scavengers; Gastric Mucosa; Humans; Interleukin-8; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Tumor Necrosis Factor-alpha	2009
Loss of CFTR results in reduction of histone deacetylase 2 in airway epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:1 Topics: Acetylation; Acetylcysteine; Cell Line; Cell Nucleus; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Knockdown Techniques; Histone Deacetylase 2; Histone Deacetylases; Humans; Interleukin-8; NF-kappa B; p300-CBP Transcription Factors; Promoter Regions, Genetic; Repressor Proteins; Respiratory System; RNA Interference; RNA, Messenger; RNA, Small Interfering	2009
Oxidative stress augments toll-like receptor 8 mediated neutrophilic responses in healthy subjects. Respiratory research, 2009, Jun-15, Volume: 10 Topics: Acetylcysteine; Chemotaxis, Leukocyte; Cytokines; Flow Cytometry; Humans; Hydrogen Peroxide; Imidazoles; Inflammation; Interleukin-8; Neutrophils; Oxidative Stress; Pancreatic Elastase; Phosphorylation; Reference Values; Signal Transduction; Toll-Like Receptor 7; Toll-Like Receptor 8; Transcription Factor RelA; Virus Diseases	2009
Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cells. American journal of respiratory cell and molecular biology, 2010, Volume: 42, Issue:6 Topics: Acetylcysteine; Active Transport, Cell Nucleus; Antioxidants; Cell Line; Cysteine Proteinase Inhibitors; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Glucocorticoids; Humans; Hydrogen Peroxide; Interferon Regulatory Factor-3; Interleukin-8; Leupeptins; Oxidants; Oxidative Stress; Poly I-C; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Respiratory Mucosa; RNA Interference; RNA, Double-Stranded; Time Factors; Toll-Like Receptor 3; Transcription Factor RelA; Up-Regulation	2010
Protective effect of NAC preconditioning against ischemia-reperfusion injury in piglet small bowel transplantation: effects on plasma TNF, IL-8, hyaluronic acid, and NO. The Journal of surgical research, 2011, Jun-15, Volume: 168, Issue:2 Topics: Acetylcysteine; Animals; Free Radical Scavengers; Hyaluronic Acid; Interleukin-8; Intestine, Small; Ischemic Preconditioning; Nitric Oxide; Random Allocation; Reperfusion Injury; Swine; Tumor Necrosis Factor-alpha	2011
Neutrophil activation in severe, early-onset COPD patients versus healthy non-smoker subjects in vitro: effects of antioxidant therapy. Respiration; international review of thoracic diseases, 2012, Volume: 83, Issue:2 Topics: Acetylcysteine; Apoptosis; Case-Control Studies; Chemotaxis; Female; Free Radical Scavengers; Humans; Interleukin-8; Leukocyte Elastase; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Sulfhydryl Compounds	2012
[Effects of high-dose N-acetylcysteine on the lung tissues of rats exposed to silica]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2011, Volume: 29, Issue:7 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Dust; Interleukin-8; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Wistar; Silicon Dioxide; Tumor Necrosis Factor-alpha	2011
Reactive oxygen species mediate Jak2/Stat3 activation and IL-8 expression in pulmonary epithelial cells stimulated with lipid-associated membrane proteins from Mycoplasma pneumoniae. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:5 Topics: Acetylcysteine; Bacterial Proteins; Cell Line; DNA; Enzyme Activation; Epithelial Cells; Humans; Interleukin-8; Janus Kinase 2; Lung; Membrane Proteins; Mycoplasma pneumoniae; NF-kappa B; Reactive Oxygen Species; STAT3 Transcription Factor; Toll-Like Receptors	2012
Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells. Oncology reports, 2012, Volume: 28, Issue:3 Topics: Acetylcysteine; Cell Line, Tumor; Free Radical Scavengers; Gene Expression; Gene Expression Regulation, Neoplastic; Glutamate-Cysteine Ligase; Glutathione; Heme Oxygenase-1; Humans; Interleukin-8; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Thymidine Phosphorylase	2012
N-acetyl-S-farnesyl-l-cysteine suppresses chemokine production by human dermal microvascular endothelial cells. Experimental dermatology, 2012, Volume: 21, Issue:9 Topics: Acetylcysteine; Adenosine Triphosphate; Cell Survival; Cells, Cultured; Chemokine CCL2; Chemokine CXCL1; Cyclic AMP; Endothelial Cells; Humans; Interleukin-8; Microvessels; RNA, Messenger; Skin; Tumor Necrosis Factor-alpha	2012
In vitro N-acetyl-L-cysteine promotes proliferation and suppresses interleukin-8 expression in adipose-derived stem cells. Aesthetic plastic surgery, 2012, Volume: 36, Issue:5 Topics: Acetylcysteine; Adipose Tissue; Cell Proliferation; Cells, Cultured; Female; Humans; Interleukin-8; Stem Cells	2012
High-dose N-acetylcysteine decreases silica-induced lung fibrosis in the rat. The Journal of international medical research, 2013, Volume: 41, Issue:4 Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; C-Reactive Protein; Hydroxyproline; Inflammation; Interleukin-8; Lung; Male; Malondialdehyde; Pulmonary Fibrosis; Rats; Rats, Wistar; Silicon Dioxide; Tumor Necrosis Factor-alpha	2013
Methemoglobin-induced signaling and chemokine responses in human alveolar epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2014, Jan-01, Volume: 306, Issue:1 Topics: Acetylcysteine; Alveolar Epithelial Cells; Antioxidants; Cell Line, Tumor; Chemokine CCL2; Chemokines; Deferoxamine; Gene Knockdown Techniques; Humans; I-kappa B Kinase; Interleukin-8; Iron Chelating Agents; MAP Kinase Signaling System; Methemoglobin; NF-kappa B; Oxidative Stress; Phenanthrolines; Phosphorylation; Protein Processing, Post-Translational; Pulmonary Alveoli; RNA Interference	2014
cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2014, Oct-15, Volume: 307, Issue:8 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcysteine; ADAM Proteins; ADAM17 Protein; Animal Feed; Animals; Bronchi; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dust; Enzyme-Linked Immunosorbent Assay; Erythromycin; Humans; Interleukin-6; Interleukin-8; Mice; Mice, Inbred C57BL; Protein Kinase C-epsilon; Swine; Tumor Necrosis Factor-alpha	2014
Reactive oxygen species mediate IL-8 expression in Down syndrome candidate region-1-overexpressed cells. The international journal of biochemistry & cell biology, 2014, Volume: 55 Topics: Acetylcysteine; Blotting, Western; Calcium; Chelating Agents; DNA-Binding Proteins; Egtazic Acid; Free Radical Scavengers; Gene Expression; HEK293 Cells; Humans; Interleukin-1beta; Interleukin-8; Intracellular Signaling Peptides and Proteins; Intracellular Space; Microscopy, Confocal; Mitochondria; Muscle Proteins; NF-kappa B; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Superoxide Dismutase-1; Transfection	2014
Investigating the immunomodulatory nature of zinc oxide nanoparticles at sub-cytotoxic levels in vitro and after intranasal instillation in vivo. Journal of nanobiotechnology, 2015, Feb-03, Volume: 13 Topics: Acetylcysteine; Administration, Intranasal; Animals; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Female; Heme Oxygenase-1; Humans; Immunologic Factors; Inflammation; Interleukin-8; MAP Kinase Signaling System; Metal Nanoparticles; Mice, Inbred BALB C; NF-kappa B; Toxicity Tests; Zinc Oxide	2015
Organic extracts from African dust storms stimulate oxidative stress and induce inflammatory responses in human lung cells through Nrf2 but not NF-κB. Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:2 Topics: Acetylcysteine; Africa; Air Movements; Air Pollutants; Cell Line; Deferoxamine; Dust; Glutathione S-Transferase pi; Heme Oxygenase-1; Humans; Inflammation; Interleukin-6; Interleukin-8; Lung; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Puerto Rico; Reactive Oxygen Species; RNA, Messenger	2015
The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation. Aging cell, 2015, Volume: 14, Issue:4 Topics: Acetylcysteine; Antioxidants; Autophagy; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cellular Senescence; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Mesenchymal Stem Cells; Mitochondria; nef Gene Products, Human Immunodeficiency Virus; NF-kappa B; Osteoblasts; Osteocalcin; Oxidative Stress; Primary Cell Culture; Recombinant Proteins; Sesquiterpenes; Signal Transduction; Sirolimus; tat Gene Products, Human Immunodeficiency Virus	2015
House dust mite allergen Der f 1 induces IL-8 in human basophilic cells via ROS-ERK and p38 signal pathways. Cytokine, 2015, Volume: 75, Issue:2 Topics: Acetylcysteine; Antigens, Dermatophagoides; Arthropod Proteins; Basophils; Cell Line, Tumor; Cloning, Molecular; Cysteine Endopeptidases; Extracellular Signal-Regulated MAP Kinases; Humans; Immunoglobulin E; Inflammation; Interleukin-8; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; RNA, Messenger; Signal Transduction	2015
Oxidative stress and endocytosis are involved in upregulation of interleukin-8 expression in airway cells exposed to PM2.5. Environmental toxicology, 2016, Volume: 31, Issue:12 Topics: Acetylcysteine; Air Pollutants; Antioxidants; Bronchi; Cell Line; Endocytosis; Epithelial Cells; Humans; Interleukin-8; Macrophages; Oxidative Stress; Particulate Matter; Reactive Oxygen Species; Respiratory Mucosa; Tumor Necrosis Factor-alpha; Up-Regulation	2016
Protective effects of the thiol compounds GSH and NAC against sulfur mustard toxicity in a human keratinocyte cell line. Toxicology letters, 2016, Feb-26, Volume: 244 Topics: Acetylcysteine; Antidotes; Apoptosis; Cell Line; Chemical Warfare Agents; Cytoprotection; Dose-Response Relationship, Drug; Glutathione; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Keratinocytes; Mustard Gas; Necrosis; Sulfhydryl Compounds; Time Factors	2016
N-Acetylcysteine attenuates tumor necrosis factor alpha levels in autoimmune inner ear disease patients. Immunologic research, 2015, Volume: 63, Issue:1-3 Topics: Acetylcysteine; Antioxidants; Autoimmune Diseases; Humans; Interleukin-8; Labyrinth Diseases; Leukocytes, Mononuclear; Molecular Targeted Therapy; Peroxidase; Tumor Necrosis Factor-alpha	2015
Induction of IL-8(CXCL8) and MCP-1(CCL2) with oxidative stress and its inhibition with N-acetyl cysteine (NAC) in cell culture model using HK-2 cell. Transplant immunology, 2016, Volume: 35 Topics: Acetylcysteine; Cell Culture Techniques; Cell Line; Chemokine CCL2; Humans; Interleukin-1beta; Interleukin-8; Kidney Transplantation; Oxidative Stress; Reperfusion Injury	2016
Fusobacterium nucleatum-Induced Impairment of Autophagic Flux Enhances the Expression of Proinflammatory Cytokines via ROS in Caco-2 Cells. PloS one, 2016, Volume: 11, Issue:11 Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Adenine; Animals; Autophagy; Autophagy-Related Protein 12; Autophagy-Related Protein 5; Caco-2 Cells; Cell Line, Tumor; Epithelial Cells; Free Radical Scavengers; Fusobacterium Infections; Fusobacterium nucleatum; Gene Expression Regulation; Humans; Interleukin-1beta; Interleukin-8; Macrolides; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha	2016
Activation of interleukin-6 and -8 expressions by methylmercury in human U937 macrophages involves RelA and p50. Journal of applied toxicology : JAT, 2017, Volume: 37, Issue:5 Topics: Acetylcysteine; Cell Survival; Free Radical Scavengers; Gene Knockdown Techniques; Humans; Interleukin-6; Interleukin-8; Macrophages; Methylmercury Compounds; NF-E2-Related Factor 2; NF-kappa B p50 Subunit; Transcription Factor RelA; U937 Cells	2017
Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options. Transplant international : official journal of the European Society for Organ Transplantation, 2017, Volume: 30, Issue:4 Topics: Acetates; Acetylcysteine; Aminopyridines; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Benzamides; Bronchi; Cell Line; Cyclopropanes; Dapsone; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Interleukin-1alpha; Interleukin-8; MAP Kinase Signaling System; Moxifloxacin; Neutrophils; Phosphorylation; Pyridones; Quinolines; Sulfides; Theophylline; Treatment Outcome	2017
Inhibition of Methylglyoxal-Induced AGEs/RAGE Expression Contributes to Dermal Protection by N-Acetyl-L-Cysteine. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 41, Issue:2 Topics: Acetylcysteine; Aged; Case-Control Studies; Cell Adhesion; Cell Line; Cell Movement; Cell Survival; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Interleukin-6; Interleukin-8; Male; Matrix Metalloproteinase 9; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Protective Agents; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Up-Regulation	2017
Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar macrophages. Thorax, 2018, Volume: 73, Issue:12 Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Survival; Chemokine CCL2; Complex Mixtures; Electronic Nicotine Delivery Systems; Gases; Humans; Inflammation; Interleukin-6; Interleukin-8; Macrophages, Alveolar; Matrix Metalloproteinase 9; Necrosis; Nicotine; Phagocytosis; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Reactive Oxygen Species; THP-1 Cells; Tumor Necrosis Factor-alpha; Vaping	2018
SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction. Cells, 2020, 04-01, Volume: 9, Issue:4 Topics: Acetylcysteine; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Cellular Senescence; Humans; Insulin Resistance; Interleukin-6; Interleukin-8; Macaca fascicularis; Mitochondria; nef Gene Products, Human Immunodeficiency Virus; Oxidative Stress; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Stem Cells; tat Gene Products, Human Immunodeficiency Virus	2020
N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM. International journal of molecular sciences, 2020, Oct-03, Volume: 21, Issue:19 Topics: Acetylcysteine; Cell Proliferation; Composite Resins; Dental Pulp; Drug Evaluation, Preclinical; Extracellular Matrix; Gene Expression Regulation, Developmental; Humans; Inflammation; Interleukin-8; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Polyethylene Glycols; Polymethacrylic Acids	2020
Differential Interleukin-8 thresholds for chemotaxis and netosis in human neutrophils. European journal of immunology, 2021, Volume: 51, Issue:9 Topics: Acetylcysteine; Chemotaxis; Extracellular Traps; Humans; Interleukin-8; Neutrophils; Reactive Oxygen Species; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Signal Transduction	2021