acetylcysteine has been researched along with indomethacin in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.44) | 18.7374 |
| 1990's | 8 (17.78) | 18.2507 |
| 2000's | 17 (37.78) | 29.6817 |
| 2010's | 14 (31.11) | 24.3611 |
| 2020's | 4 (8.89) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Dornberger, K; Gebhardt, P; Gollmick, FA; Görls, H; Gräfe, U; Härtl, A; Hertweck, C; Schlegel, B | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Gan, H; Ma, L; Sang, D; Su, L; Wang, R; Wu, Y; Yang, G; Zhang, L; Zhou, J | 1 |
| Huang, W; Huang, Y; Ma, L; Wang, R; Yang, G | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Bistoni, F; Calabresi, A; Perito, S; Romani, L | 1 |
| Brune, K; Szelenyi, I | 1 |
| Smith, RL; Williams, RT | 1 |
| Earp, HS; Huckle, WR | 1 |
| Chen, F; Demers, LM; Gaydos, LJ; Kuhn, DC; Sun, SC | 1 |
| Eriksson, UJ; Wentzel, P | 1 |
| Chong, YH; Park, HK; Seoh, JY | 1 |
| Boulares, H; Giardina, C; Inan, MS | 1 |
| Bernareggi, M; Berti, F; Chiesara, E; Oriani, G; Radice, S; Rossoni, G | 1 |
| Ahmad, M; Li, WQ; Morin, I; Su, S; Zafarullah, M | 1 |
| Huh, SO; Kim, YH; Lee, JK; Song, DK; Suh, HW; Won, JS | 1 |
| Fuji, Y; Kai, M; Kawasaki, H; Matsura, T; Yamada, K | 1 |
| Chen, YC; Lee, WR; Lin, JK; Shen, SC; Tsai, SH | 1 |
| Albanese, C; D'Amico, M; Hawcroft, G; Hull, MA; Markham, AF; Pestell, RG | 1 |
| Andersson, R; Deng, X; Lasson, A; Olanders, K; Sun, Z | 1 |
| Ruh, J; Schmidt, E; Vogel, F | 1 |
| Barkan, D; Deharo, E; Ginsburg, H; Golenser, J; Krugliak, M | 1 |
| Davies, JE; Jennings, SC; Ng, LL; Pettit, AI; Quinn, PA; Wong, RK | 1 |
| De Cock, K; De Muynck, M; Rimbaut, S; Van Maele, G; Vanden Bossche, LC; Vanderstraeten, GG; Vertriest, S; Wojtowicz, I | 1 |
| Gendron, ME; Thorin, E | 1 |
| Chiou, SK; Mandayam, S | 1 |
| Fela, DA; Gonzalez, AV; Gordon, JS; Perez, E; Rouzard, K; Sarngadharan, G; Stock, JB; Stock, MB; Wolanin, PM | 1 |
| Carvalho, AC; de Queiroz, SS; Guedes, MM; Lima, AF; Lira, SR; Rao, VS; Santos, FA; Silveira, ER | 1 |
| Albuquerque, RL; de Andrade, GM; de Morais, SM; de Souza, CM; Rao, VS; Rodrigues, Pde A; Santos, FA; Silva, AR; Silva, MG | 1 |
| Bien, MY; Hsu, CC; Hsu, HC; Kou, YR; Lin, YS; Weng, HT | 1 |
| Araújo, JH; Cardoso, MR; Dal-Pizzol, F; Daufenbach, JF; Gonçalves, CL; Petronilho, FC; Rezin, GT; Roesler, R; Schwartsmann, G; Streck, EL | 1 |
| Arbogast, S; Brooks, SV; Dowling, JJ; Ferreiro, A; Hur, J; Kuwada, JY; Lunardi, J; Marty, I; McEvoy, A; Nelson, DD; Waugh, T | 1 |
| Ho, CY; Kou, YR; Lai, CJ; Liu, BY; Lu, SH; Tsai, TL | 1 |
| Atalay, F; Aydin, O; Cadirci, E; Cakir, A; Halici, M; Halici, Z; Odabasoglu, F | 1 |
| Ali, DA; Katary, MA; Soliman, NA; Zineldeen, DH | 1 |
| Abd-Ellatif, RN; Hegab, II; Sadek, MT | 1 |
| Deng, C; Guo, S; Hou, Y; Li, C; Peng, M; Teng, Y; Wu, T; Yi, D; Zhang, Q | 1 |
2 review(s) available for acetylcysteine and indomethacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Comparative metabolism of drugs in man and monkeys.
Topics: Acetylation; Acetylcysteine; Amino Acids; Animals; Carbon Radioisotopes; Cats; Cricetinae; Dogs; Glucuronates; Glutamates; Glycine; Guinea Pigs; Haplorhini; Humans; Indoleacetic Acids; Indomethacin; Methylation; Mice; Pharmaceutical Preparations; Phenols; Rabbits; Rats; Species Specificity; Sulfadimethoxine | 1974 |
43 other study(ies) available for acetylcysteine and indomethacin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill).
Topics: Anti-Inflammatory Agents; Basidiomycota; Benzopyrans; Chemistry, Pharmaceutical; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Design; Horseradish Peroxidase; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Xanthine Oxidase | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Design, synthesis and biological evaluation of novel osthole-based derivatives as potential neuroprotective agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Coumarins; Drug Design; Humans; Molecular Docking Simulation; Neuroprotective Agents; Peptide Fragments; Structure-Activity Relationship | 2020 |
Design and synthesis of novel diosgenin-triazole hybrids targeting inflammation as potential neuroprotective agents.
Topics: Alzheimer Disease; Animals; Cell Line; Diosgenin; Dose-Response Relationship, Drug; Drug Design; Inflammation; Lipopolysaccharides; Molecular Conformation; Neuroprotective Agents; Nitric Oxide; Rats; Structure-Activity Relationship; Triazoles | 2021 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Drug-induced modulation of IL-2 production in experimental murine trypanosomiasis.
Topics: Acetylcysteine; Animals; Female; In Vitro Techniques; Indomethacin; Interleukin-2; Male; Mice; Receptors, Interleukin-2; Spleen; T-Lymphocytes, Regulatory; Trypanosomiasis | 1992 |
Possible role of sulfhydryls in mucosal protection induced by aluminum hydroxide.
Topics: Acetylcysteine; Aluminum Hydroxide; Animals; Ethanol; Ethylmaleimide; Gastric Mucosa; Indomethacin; Male; Premedication; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1986 |
Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols.
Topics: Acetylcysteine; Angiotensin II; Animals; Calcimycin; Cell Line; Cell Line, Transformed; Drug Synergism; Egtazic Acid; Enzyme Activation; Flavonoids; Flavonols; Indomethacin; Liver; Masoprocol; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quercetin; Rats; Tyrosine; Vanadates | 1994 |
Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages.
Topics: Acetylcysteine; Alkaloids; Animals; Arginine; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Molecular Sequence Data; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotide Probes; omega-N-Methylarginine; Protein Kinase C; Silicon Dioxide; Staurosporine; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine | 1995 |
Antioxidants diminish developmental damage induced by high glucose and cyclooxygenase inhibitors in rat embryos in vitro.
Topics: Acetylcysteine; Animals; Antioxidants; Arachidonic Acid; Aspirin; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Embryo, Mammalian; Embryonic and Fetal Development; Glucose; Indomethacin; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 1998 |
Increased activity of matrix metalloproteinase-2 in human glial and neuronal cell lines treated with HIV-1 gp41 peptides.
Topics: Acetylcysteine; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Antiviral Agents; Cell Line; Culture Media, Conditioned; Dexamethasone; Gelatinases; Glutathione; HIV Envelope Protein gp41; HIV-1; Humans; Indomethacin; Matrix Metalloproteinase 2; Metalloendopeptidases; Mice; Molecular Weight; Neuroglia; Neurons; Recombinant Proteins; Tumor Cells, Cultured | 1998 |
NSAIDs and butyrate sensitize a human colorectal cancer cell line to TNF-alpha and Fas ligation: the role of reactive oxygen species.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antioxidants; Apoptosis; Butyrates; Colorectal Neoplasms; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Indomethacin; Membrane Glycoproteins; NF-kappa B; Reactive Oxygen Species; Salicylic Acid; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Hyperbaric oxygen increases plasma exudation in rat trachea: involvement of nitric oxide.
Topics: Acetylcysteine; Animals; Anti-Asthmatic Agents; Blood Pressure; Blotting, Western; Capillary Permeability; Enzyme Inhibitors; Fluocinolone Acetonide; Free Radical Scavengers; Heart Rate; Hemodynamics; Hyperbaric Oxygenation; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Stereoisomerism; Trachea | 1999 |
Induction of stromelysin gene expression by tumor necrosis factor alpha is inhibited by dexamethasone, salicylate, and N-acetylcysteine in synovial fibroblasts.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cattle; Cells, Cultured; Dexamethasone; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Ibuprofen; Indomethacin; Matrix Metalloproteinase 3; Proline; Sodium Salicylate; Synovial Membrane; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vitamin E | 1999 |
Stimulation of astrocyte-enriched culture with arachidonic acid increases proenkephalin mRNA: involvement of proto-oncoprotein and mitogen activated protein kinases.
Topics: Acetylcysteine; Animals; Animals, Newborn; Arachidonic Acid; Astrocytes; Cerebral Cortex; DNA-Binding Proteins; Enkephalins; Enzyme Activation; Fos-Related Antigen-2; Gene Expression Regulation; Indomethacin; Masoprocol; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Precursors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factors; Transcription, Genetic | 2000 |
Protection by polaprezinc, an anti-ulcer drug, against indomethacin-induced apoptosis in rat gastric mucosal cells.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Apoptosis; Carnosine; Cells, Cultured; Cytochrome c Group; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Gastric Mucosa; Indomethacin; Organometallic Compounds; Peptide Hydrolases; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors; Zinc; Zinc Compounds; Zinc Sulfate | 2000 |
Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells.
Topics: Acetylcysteine; Arsenites; Blotting, Northern; Blotting, Western; Colorectal Neoplasms; Curcumin; Cyclooxygenase Inhibitors; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Indomethacin; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells.
Topics: Acetylcysteine; beta Catenin; Blotting, Western; Colorectal Neoplasms; Cyclin D1; Cytoskeletal Proteins; Desmoplakins; DNA; Dose-Response Relationship, Drug; Down-Regulation; Electrophoretic Mobility Shift Assay; gamma Catenin; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Interleukin-2; Isoenzymes; Nitrobenzenes; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C beta; Proto-Oncogene Proteins c-myc; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sulfonamides; Trans-Activators; Transcription Factors; Tumor Cells, Cultured | 2002 |
Gut barrier permeability, reticuloendothelial system function and protease inhibitor levels following intestinal ischaemia and reperfusion--effects of pretreatment with N-acetyl-L-cysteine and indomethacin.
Topics: Acetylcysteine; Animals; Cyclooxygenase Inhibitors; Endothelium; Epithelium; Free Radical Scavengers; Indomethacin; Intestinal Mucosa; Intestines; Male; Mononuclear Phagocyte System; Permeability; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2002 |
Effect of N-acetylcysteine on microcirculation of mucosa in rat ileum in a model of intestinal inflammation.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Indomethacin; Inflammation; Intestinal Mucosa; Intestine, Small; Male; Microcirculation; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Statistics, Nonparametric | 2003 |
Potentiation of the antimalarial action of chloroquine in rodent malaria by drugs known to reduce cellular glutathione levels.
Topics: Acetaminophen; Acetylcysteine; Aminoquinolines; Animals; Antimalarials; Chloroquine; Disulfiram; Drug Synergism; Glutathione; Indomethacin; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum | 2003 |
Advanced glycation end products stimulate an enhanced neutrophil respiratory burst mediated through the activation of cytosolic phospholipase A2 and generation of arachidonic Acid.
Topics: Acetylcysteine; Adult; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Enzyme Inhibitors; Glycation End Products, Advanced; Group IV Phospholipases A2; Humans; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organophosphonates; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Quinacrine; Reactive Oxygen Species; Respiratory Burst; Vascular Diseases | 2003 |
Free radical scavengers are more effective than indomethacin in the prevention of experimentally induced heterotopic ossification.
Topics: Acetylcysteine; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Double-Blind Method; Drug Synergism; Female; Free Radical Scavengers; Hindlimb; Indomethacin; Ossification, Heterotopic; Osteogenesis; Rabbits; Radiography; Random Allocation | 2007 |
A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice.
Topics: Acetylcholine; Acetylcysteine; Aging; Animals; Antioxidants; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Catechin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Gene Expression Regulation, Enzymologic; Hydrazines; Indomethacin; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Oxidation-Reduction; Reactive Oxygen Species; Receptors, Thromboxane A2, Prostaglandin H2; Renal Artery; RNA, Messenger; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasodilator Agents | 2007 |
NSAIDs enhance proteasomic degradation of survivin, a mechanism of gastric epithelial cell injury and apoptosis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line; Cysteine Proteinase Inhibitors; Epithelial Cells; Indomethacin; Leupeptins; Microtubule-Associated Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; RNA, Messenger; Stomach; Survivin; Ubiquitination | 2007 |
Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site.
Topics: Acetylcysteine; Administration, Topical; Animals; Animals, Outbred Strains; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis; Dexamethasone; Disease Models, Animal; Ear, External; Edema; Enzyme Inhibitors; Indomethacin; Male; Mice; Mice, Inbred ICR; Neutrophils; Peroxidase | 2008 |
Gastroprotective mechanisms of centipedic acid, a natural diterpene from Egletes viscosa LESS.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Asteraceae; Capsaicin; Central Nervous System Depressants; Diterpenes; Drug Interactions; Enzyme Inhibitors; Ethanol; Fatty Acids, Unsaturated; Free Radical Scavengers; Furans; Gastric Mucosa; Glyburide; Hypoglycemic Agents; Indomethacin; Male; Mice; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Oxidative Stress; Pylorus; Stomach Ulcer; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances | 2008 |
Gastroprotective effect of barbatusin and 3-beta-hydroxy-3-deoxibarbatusin, quinonoid diterpenes isolated from Plectranthus grandis, in ethanol-induced gastric lesions in mice.
Topics: Acetylcysteine; Animals; Anti-Ulcer Agents; Antioxidants; Capsaicin; Disease Models, Animal; Diterpenes; Ethanol; Gastric Mucosa; Glyburide; Indomethacin; Male; Mice; Mucus; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Extracts; Plant Leaves; Plectranthus; Quinones; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Thiobarbiturates | 2010 |
Activations of TRPA1 and P2X receptors are important in ROS-mediated stimulation of capsaicin-sensitive lung vagal afferents by cigarette smoke in rats.
Topics: Acetylcysteine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Ankyrins; Antioxidants; Apyrase; Blood Pressure; Calcium Channels; Capsaicin; Cyclooxygenase Inhibitors; Heart Rate; Indomethacin; Inhalation Exposure; Lung; Male; Neurons, Afferent; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reflex; Respiration, Artificial; Respiratory Mechanics; Sensory System Agents; Signal Transduction; Smoke; Smoking; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels; Vagus Nerve | 2010 |
Gastrin-releasing peptide receptor antagonist or N-acetylcysteine combined with omeprazol protect against mitochondrial complex II inhibition in a rat model of gastritis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bombesin; Drug Therapy, Combination; Electron Transport; Electron Transport Complex II; Electron Transport Complex III; Gastric Mucosa; Gastritis; Indomethacin; Male; Mitochondria; Omeprazole; Peptide Fragments; Proton Pump Inhibitors; Rats; Rats, Wistar; Receptors, Bombesin; Severity of Illness Index; Stomach; Stomach Ulcer | 2011 |
Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy.
Topics: Acetophenones; Acetylcysteine; Animals; Animals, Genetically Modified; Antioxidants; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Humans; Indomethacin; Larva; Microarray Analysis; Microscopy, Electron, Transmission; Mitochondria; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Diseases; Mutation; Oxidative Stress; Ryanodine Receptor Calcium Release Channel; Zebrafish | 2012 |
Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats.
Topics: Acetanilides; Acetylcysteine; Animals; Antioxidants; Apnea; Calcium Channels; Capsaicin; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Indomethacin; Laryngeal Nerves; Larynx; Neurons, Afferent; Purines; Rats; Reactive Oxygen Species; Smoking; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels | 2013 |
N-Acetyl Cysteine Has Both Gastro-Protective and Anti-Inflammatory Effects in Experimental Rat Models: Its Gastro-Protective Effect Is Related to Its In Vivo and In Vitro Antioxidant Properties.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Catalase; Drug Evaluation, Preclinical; Edema; Glutathione Transferase; Indomethacin; Lipid Peroxidation; Oxidative Stress; Peroxidase; Rats, Wistar; Stomach; Stomach Ulcer; Superoxide Dismutase | 2016 |
N-acetylcysteine a possible protector against indomethacin-induced peptic ulcer: crosstalk between antioxidant, anti-inflammatory, and antiapoptotic mechanisms.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Apoptosis; Caspase 3; Chemical and Drug Induced Liver Injury; Chemokines, CXC; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Glucosephosphate Dehydrogenase; Humans; Indomethacin; Interferon-gamma; Interleukin-1beta; Male; Oxidation-Reduction; Pain; Peroxidase; Proto-Oncogene Proteins c-bcl-2; Ranitidine; Rats; Rats, Wistar; Stomach Ulcer | 2017 |
The gastroprotective effect of N-acetylcysteine and genistein in indomethacin-induced gastric injury in rats.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Gastric Mucosa; Genistein; Humans; Indomethacin; Male; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Stomach Ulcer | 2018 |
Integration of transcriptomic and proteomic analyses reveals protective mechanisms of N-acetylcysteine in indomethacin-stimulated enterocytes.
Topics: Acetylcysteine; Animals; Apoptosis; Enterocytes; Humans; Indomethacin; Proteomics; Swine; Transcriptome | 2023 |