acetylcysteine and hydroxyl radical

acetylcysteine has been researched along with hydroxyl radical in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.88)18.7374
1990's14 (34.15)18.2507
2000's13 (31.71)29.6817
2010's12 (29.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, CP; Sun, JZ; Tang, LD; Tang, ZM; Wu, K1
Aruoma, OI; Butler, J; Halliwell, B; Hoey, BM1
Cervantes, A; Lankelma, J; Pinedo, HM; Schuurhuis, GJ1
Brunet, C; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Lebegue, N; Luyckx, M1
de Graaf, L; de Vos, NM; Nottet, HS; van Asbeck, BS; Verhoef, J; Visser, MR1
Boily, MJ; Brunet, J; Cordeau, S; Des Rosiers, C1
Felix, K; Pairet, M; Zimmermann, R1
Maes, P; Nève, J; Vanderbist, F1
Cadenas, E; Qiu, XB1
Amar, M; Bridey, F; de Prost, D; Hakim, J; Khechai, F; Ollivier, V1
Supinski, G1
Grossman, N; Halevy, S; Lubart, R; Reuveni, H; Schneid, N1
Cartiglia, C; De Flora, S; Gasparini, L; Izzotti, A; Orlando, M; Scatolini, L; Tulimiero, L1
Ozawa, T; Shimazu, Y; Takai, M; Ueda, J1
Castranova, V; Colburn, NH; Ding, M; Leonard, SS; Li, JJ; Shi, X; Vallyathan, V; Ye, JP1
Butterfield, DA; La Fontaine, M; Pocernich, CB1
Aggarwal, BB; Shrivastava, A1
Hermida-Ameijeiras, A; Labandeira-García, JL; López-Martín, ME; Méndez-Alvarez, E; Soto-Otero, R1
Huang, X; Zhang, Q1
Douglas, P; Kurz, EU; Lees-Miller, SP1
Lin, HC; Shiah, IS; Tung, CS; Wan, FJ1
Chang, CP; Huang, WT; Lin, MT1
Bryla, J; Drozak, J; Fraczyk, T; Malinska, D; Winiarska, K1
Su, M; Yang, G; Yang, Y1
Abe, S; Ishizawa, K; Kanematsu, Y; Kawazoe, K; Minakuchi, K; Ohnishi, H; Tamaki, T; Torii, M; Tsuchiya, K; Yoshizumi, M1
Han, YH; Kim, SH; Kim, SZ; Park, WH1
Huang, KF; Huang, WT; Lin, MT; Niu, KC1
Meyerstein, D; Meyerstein, N; Rachmilovich-Calis, S1
Agnihotri, N; Mishra, PC1
Chanvorachote, P; Leonard, SS; Luanpitpong, S; Nimmannit, U; Pongrakhananon, V; Rojanasakul, Y; Wang, L1
Chen, S; Fan, S; Ikejima, T; Li, L; Onodera, S; Qi, M; Tashiro, S; Yu, Y1
Beach, DG; Gabryelski, W; Manderville, RA; Witham, AA1
Kim, MK; Koh, G; Lee, DH; Yang, EJ1
Fan, SM; Ikejima, T; Onodera, S; Song, JK; Tashiro, S; Yu, Y1
Hayashi, T; He, H; Ikejima, T; Liu, W; Onodera, S; Tashiro, S; Xu, Q; Yu, Y; Zang, L; Zheng, N1
Chen, TH; Liao, FT; Wang, JC; Wang, JJ; Wu, NC; Yang, YC1
Al-Anati, L; Andersson, PL; Bergman, Å; Högberg, J; Stenius, U; Strid, A; Viluksela, M1
Jayakumar, T; Li, JY; Lin, CY; Lin, KC; Lu, WJ; Pitchairaj, G; Sheu, JR1
Cai, M; Chibana, H; Fujii, K; Hara, M; Iwatani, S; Kajiwara, S; Kojima, S; Kuo, TF; Li, M; Lu, J; Oshima, Y; Qin, XY; Shrestha, R; Takahashi-Nakaguchi, A; Teraoka, R1
Fujiwara, K; Imaue, S; Jawaid, P; Kondo, T; Mitsuhashi, Y; Moniruzzaman, R; Noguchi, K; Noguchi, M; Ogawa, R; Rehman, MU; Saitoh, JI; Tomihara, K; Zhao, QL1
Hori, M; Okazaki, Y; Tanaka, H; Toyokuni, S1

Reviews

1 review(s) available for acetylcysteine and hydroxyl radical

ArticleYear
Free radical induced respiratory muscle dysfunction.
    Molecular and cellular biochemistry, 1998, Volume: 179, Issue:1-2

    Topics: Acetylcysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydroxyl Radical; Muscle Contraction; Muscle Fatigue; Reactive Oxygen Species; Respiratory Muscles; Superoxides

1998

Other Studies

40 other study(ies) available for acetylcysteine and hydroxyl radical

ArticleYear
Beneficial effects of N-acetylcysteine and cysteine in stunned myocardium in perfused rat heart.
    British journal of pharmacology, 1991, Volume: 102, Issue:3

    Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Coronary Circulation; Cystamine; Cysteine; Female; Hydroxyl Radical; Male; Myocardial Stunning; Perfusion; Rats; Rats, Wistar; Superoxides

1991
The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid.
    Free radical biology & medicine, 1989, Volume: 6, Issue:6

    Topics: Acetylcysteine; alpha 1-Antitrypsin; Antioxidants; Blood Proteins; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Pancreatic Elastase; Protease Inhibitors; Superoxides

1989
The role of oxygen-derived free radicals in the cytotoxicity of doxorubicin in multidrug resistant and sensitive human ovarian cancer cells.
    Cancer letters, 1988, Aug-15, Volume: 41, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Benzoates; Benzoic Acid; Catalase; Cell Division; Cell Survival; Doxorubicin; Drug Resistance; Female; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Kinetics; Mannitol; Ovarian Neoplasms; Oxygen; Superoxide Dismutase; Tumor Cells, Cultured

1988
Scavenging of reactive oxygen species by letosteine, a molecule with two blocked-SH groups. Comparison with free-SH drugs.
    Pharmacy world & science : PWS, 1995, May-26, Volume: 17, Issue:3

    Topics: Acetylcysteine; Antioxidants; Dose-Response Relationship, Drug; Drug Interactions; Expectorants; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Hypochlorous Acid; Mesna; Reactive Oxygen Species; Respiratory Burst; Superoxides; Thiazoles; Thiazolidines

1995
Role for oxygen radicals in self-sustained HIV-1 replication in monocyte-derived macrophages: enhanced HIV-1 replication by N-acetyl-L-cysteine.
    Journal of leukocyte biology, 1994, Volume: 56, Issue:6

    Topics: Acetylcysteine; Drug Interactions; Ferrous Compounds; Free Radical Scavengers; Glutathione; HIV-1; Humans; Hydroxyl Radical; Macrophages; Oxidation-Reduction; Reactive Oxygen Species; Stimulation, Chemical; Thiourea; Urea; Virus Replication

1994
Effects of N-acetylcysteine in the rat heart reperfused after low-flow ischemia: evidence for a direct scavenging of hydroxyl radicals and a nitric oxide-dependent increase in coronary flow.
    Free radical biology & medicine, 1995, Volume: 19, Issue:5

    Topics: Acetylcysteine; Animals; Coronary Circulation; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Heart; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nitric Oxide; Rats; Rats, Sprague-Dawley; Time Factors

1995
The antioxidative activity of the mucoregulatory agents: ambroxol, bromhexine and N-acetyl-L-cysteine. A pulse radiolysis study.
    Life sciences, 1996, Volume: 59, Issue:14

    Topics: Acetylcysteine; Ambroxol; Antioxidants; Bromhexine; Expectorants; Hydroxyl Radical; Kinetics; Pulse Radiolysis; Superoxides

1996
In vitro comparative assessment of the antioxidant activity of nacystelyn against three reactive oxygen species.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:8

    Topics: Acetylcysteine; Antioxidants; Captopril; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Lysine; Reactive Oxygen Species

1996
The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
    Archives of biochemistry and biophysics, 1997, Oct-15, Volume: 346, Issue:2

    Topics: Acetylcysteine; Aziridines; Benzoquinones; Blotting, Northern; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dicumarol; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Pentetic Acid; Quinones; Reactive Oxygen Species; RNA, Messenger; Tumor Cells, Cultured

1997
Effect of advanced glycation end product-modified albumin on tissue factor expression by monocytes. Role of oxidant stress and protein tyrosine kinase activation.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Acetylcysteine; Antioxidants; Benzoquinones; Diabetes Complications; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation; Glycation End Products, Advanced; Glycosylation; Humans; Hydroxyl Radical; Lactams, Macrocyclic; Monocytes; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Serum Albumin; Serum Albumin, Human; Signal Transduction; Thrombophilia; Thromboplastin

1997
780 nm low power diode laser irradiation stimulates proliferation of keratinocyte cultures: involvement of reactive oxygen species.
    Lasers in surgery and medicine, 1998, Volume: 22, Issue:4

    Topics: Acetates; Acetylcysteine; Antioxidants; Catalase; Cell Count; Cell Division; Cells, Cultured; Enzyme Inhibitors; Follow-Up Studies; Free Radical Scavengers; Histidine; Humans; Hydrogen Peroxide; Hydroxyl Radical; Keratinocytes; Lasers; Lipid Peroxidation; Mannitol; Radiopharmaceuticals; Reactive Oxygen Species; Sodium Azide; Superoxide Dismutase; Superoxides; Thymidine; Tritium; Vitamin E

1998
In vitro inhibition by N-acetylcysteine of oxidative DNA modifications detected by 32P postlabeling.
    Free radical research, 1998, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Cattle; Chromatography, Thin Layer; Copper Sulfate; DNA; DNA Adducts; DNA Damage; DNA Fragmentation; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Isotope Labeling; Oxidation-Reduction; Phosphorus Radioisotopes; Reactive Oxygen Species

1998
Reactive oxygen species generated from the reaction of copper(II) complexes with biological reductants cause DNA strand scission.
    Archives of biochemistry and biophysics, 1998, Sep-15, Volume: 357, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Copper; DNA Damage; Electron Spin Resonance Spectroscopy; Glutathione; Hydrogen Peroxide; Hydroquinones; Hydroxyl Radical; Oxidation-Reduction; Plasmids; Reactive Oxygen Species; Reducing Agents; Spin Trapping

1998
Vanadate-induced activation of activator protein-1: role of reactive oxygen species.
    Carcinogenesis, 1999, Volume: 20, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Line; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Epidermal Cells; Formates; Free Radical Scavengers; Gene Expression Regulation; Genes, Reporter; Hydrogen Peroxide; Hydroxyl Radical; Luciferases; Mice; NADP; Naphthalenes; Oxidation-Reduction; Oxygen Consumption; Protein Kinase C; Reactive Oxygen Species; Recombinant Fusion Proteins; Superoxide Dismutase; Superoxides; Transcription Factor AP-1; Transcriptional Activation; Transfection; Vanadates

1999
In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain.
    Neurochemistry international, 2000, Volume: 36, Issue:3

    Topics: Acetylcysteine; Animals; Brain; Ferrous Compounds; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Male; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Synaptosomes

2000
Antioxidants differentially regulate activation of nuclear factor-kappa B, activator protein-1, c-jun amino-terminal kinases, and apoptosis induced by tumor necrosis factor: evidence that JNK and NF-kappa B activation are not linked to apoptosis.
    Antioxidants & redox signaling, 1999,Summer, Volume: 1, Issue:2

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Enzyme Activation; Enzyme Inhibitors; Glutathione; Humans; Hydroxyl Radical; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Mitogen-Activated Protein Kinases; NF-kappa B; Pyrrolidines; Superoxides; Thiocarbamates; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; U937 Cells

1999
Effect of iron and manganese on hydroxyl radical production by 6-hydroxydopamine: mediation of antioxidants.
    Free radical biology & medicine, 2001, Oct-15, Volume: 31, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Corpus Striatum; Cysteine; Female; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Iron; Manganese; Oxidation-Reduction; Oxidopamine; Rats; Rats, Sprague-Dawley

2001
Induction of interleukin-6 by coal containing bioavailable iron is through both hydroxyl radical and ferryl species.
    Journal of biosciences, 2003, Volume: 28, Issue:1

    Topics: Acetylcysteine; Biological Availability; Catalase; Cell Line; Coal; Coal Mining; Epithelial Cells; Humans; Hydroxyl Radical; Interleukin-6; Iron; Lung; Oxidants; Particle Size; Pneumoconiosis; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase

2003
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Nucleus; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Histones; Humans; Hydroxyl Radical; Image Processing, Computer-Assisted; Immunoblotting; Immunoprecipitation; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Radiation, Ionizing; Reactive Oxygen Species; Serine; Signal Transduction; Threonine; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin

2004
Effects of alpha-phenyl-N-tert-butyl nitrone and N-acetylcysteine on hydroxyl radical formation and dopamine depletion in the rat striatum produced by d-amphetamine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:2

    Topics: Acetylcysteine; Animals; Body Temperature; Cyclic N-Oxides; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Microdialysis; Neostriatum; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrogen Oxides; Pilot Projects; Rats; Rats, Sprague-Dawley

2006
An NMDA receptor-dependent hydroxyl radical pathway in the rabbit hypothalamus may mediate lipopolysaccharide fever.
    Neuropharmacology, 2006, Volume: 50, Issue:4

    Topics: Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Body Temperature; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fever; Hydroxybenzoates; Hydroxyl Radical; Isoquinolines; Lipopolysaccharides; Male; Rabbits; Receptors, N-Methyl-D-Aspartate; Thioctic Acid

2006
Melatonin attenuates diabetes-induced oxidative stress in rabbits.
    Journal of pineal research, 2006, Volume: 40, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione; Hydroxyl Radical; Kidney Cortex; Liver; Male; Melatonin; Oxidative Stress; Rabbits

2006
Quantitative measurement of hydroxyl radical induced DNA double-strand breaks and the effect of N-acetyl-L-cysteine.
    FEBS letters, 2006, Jul-24, Volume: 580, Issue:17

    Topics: Acetylcysteine; Animals; DNA Damage; Humans; Hydroxyl Radical; Microscopy, Atomic Force; Nucleic Acid Conformation; Plasmids

2006
Calcium and reactive oxygen species mediated Zn2+ -induced apoptosis in PC12 cells.
    Journal of pharmacological sciences, 2006, Volume: 102, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; Bisbenzimidazole; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Radioisotopes; Cell Survival; Dantrolene; Fluorescent Dyes; Free Radical Scavengers; Hydroxyl Radical; PC12 Cells; Rats; Reactive Oxygen Species; Spectrophotometry, Atomic; Zinc

2006
Pyrogallol as a glutathione depletor induces apoptosis in HeLa cells.
    International journal of molecular medicine, 2008, Volume: 21, Issue:6

    Topics: Acetylcysteine; Annexin A5; Antioxidants; Apoptosis; Catalase; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescein-5-isothiocyanate; Free Radical Scavengers; Glutathione; HeLa Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Membrane Potential, Mitochondrial; Mitochondria; Models, Biological; Pyrogallol; Reactive Oxygen Species; Superoxide Dismutase; Superoxides

2008
Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits.
    European journal of pharmacology, 2009, Mar-15, Volume: 606, Issue:1-3

    Topics: Acetylcysteine; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Body Temperature; Dinoprostone; Glutamic Acid; Hydroxyl Radical; Hyperbaric Oxygenation; Hypothalamus; Injections; Interleukin-6; Lipopolysaccharides; Male; Oxygen; Rabbits

2009
A mechanistic study of the effects of antioxidants on the formation of malondialdehyde-like products in the reaction of hydroxyl radicals with deoxyribose.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2009, Aug-03, Volume: 15, Issue:31

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Deoxyribose; Hydroxyl Radical; Malondialdehyde; Sulfhydryl Compounds; Thermodynamics

2009
Mechanism of scavenging action of N-acetylcysteine for the OH radical: a quantum computational study.
    The journal of physical chemistry. B, 2009, Sep-03, Volume: 113, Issue:35

    Topics: Acetylcysteine; Biophysics; Carbon; Computer Simulation; Free Radicals; Hydrogen; Hydroxyl Radical; Models, Chemical; Molecular Conformation; Quantum Theory; Software; Solvents; Temperature; Thermodynamics

2009
Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:8

    Topics: Acetylcysteine; Alopecia; Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Catalase; Cell Line; Cell Survival; Cisplatin; Formates; Hair Follicle; Humans; Hydroxyl Radical; Keratinocytes; Metalloporphyrins; Proto-Oncogene Proteins c-bcl-2; Ubiquitination

2011
Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells.
    Free radical research, 2011, Volume: 45, Issue:11-12

    Topics: Acetylcysteine; Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Caspase 3; Cell Survival; Glutathione; HeLa Cells; Humans; Hydroxyl Radical; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Reactive Nitrogen Species; Reactive Oxygen Species; Silybin; Silymarin

2011
Hydroxyl radical-induced oxidation of a phenolic C-linked 2'-deoxyguanosine adduct yields a reactive catechol.
    Chemical research in toxicology, 2012, Feb-20, Volume: 25, Issue:2

    Topics: Acetylcysteine; Catechols; Copper; Deoxyguanosine; DNA Adducts; Edetic Acid; Ferrous Compounds; Hydrogen Peroxide; Hydroxyl Radical; Phenols

2012
Gliclazide does not fully prevent 2-deoxy-D-ribose-induced oxidative damage because it does not restore glutathione content in a pancreatic β-cell line.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Cell Survival; Cricetinae; Deoxyribose; Drug Interactions; Gliclazide; Glutathione; Hydroxyl Radical; Hypoglycemic Agents; Insulin-Secreting Cells; Oxidative Stress; Reactive Oxygen Species

2012
Hydroxyl radical (·OH) played a pivotal role in oridonin-induced apoptosis and autophagy in human epidermoid carcinoma A431 cells.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:12

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Down-Regulation; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Isodon; Membrane Potential, Mitochondrial; Oxidative Stress; Phytotherapy; Plant Extracts; Protein-Tyrosine Kinases; Signal Transduction

2012
Reactive oxygen species H2O2 and •OH, but not O2•(-) promote oridonin-induced phagocytosis of apoptotic cells by human histocytic lymphoma U937 cells.
    International immunopharmacology, 2013, Volume: 15, Issue:2

    Topics: Acetylcysteine; Apoptosis; Autophagy; Diterpenes, Kaurane; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lymphoma, Large B-Cell, Diffuse; MAP Kinase Signaling System; Phagocytosis; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; raf Kinases; ras Proteins; Reactive Oxygen Species; U937 Cells

2013
N-acetylcysteine improves cardiac contractility and ameliorates myocardial injury in a rat model of lung ischemia and reperfusion injury.
    Transplantation proceedings, 2013, Volume: 45, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Bronchoalveolar Lavage Fluid; Creatine Kinase, MB Form; Cytoprotection; Disease Models, Animal; Hydroxyl Radical; Lipid Peroxidation; Lung; Lung Injury; Male; Myocardial Contraction; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Troponin I; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure

2013
Hydroxyl metabolite of PCB 180 induces DNA damage signaling and enhances the DNA damaging effect of benzo[a]pyrene.
    Chemico-biological interactions, 2015, Sep-05, Volume: 239

    Topics: Acetylcysteine; Animals; Benzo(a)pyrene; Checkpoint Kinase 1; Cytochrome P-450 CYP1A1; DNA Damage; Drug Synergism; Estradiol; Female; Hep G2 Cells; Histones; Humans; Hydroxyl Radical; Liver; Male; Polychlorinated Biphenyls; Protein Kinases; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction

2015
Nobiletin, a citrus flavonoid, activates vasodilator-stimulated phosphoprotein in human platelets through non-cyclic nucleotide-related mechanisms.
    International journal of molecular medicine, 2017, Volume: 39, Issue:1

    Topics: Acetylcysteine; Blood Platelets; Cell Adhesion Molecules; Citrus; Electron Spin Resonance Spectroscopy; Flavones; Flavonoids; Humans; Hydroxyl Radical; Intracellular Space; Microfilament Proteins; Mitogen-Activated Protein Kinases; NADPH Oxidases; NF-kappa B; Nucleotides, Cyclic; Phosphoproteins; Phosphorylation; Protein Carbonylation; Protein Kinase C; Proto-Oncogene Proteins c-akt

2017
Fungus-derived hydroxyl radicals kill hepatic cells by enhancing nuclear transglutaminase.
    Scientific reports, 2017, 07-06, Volume: 7, Issue:1

    Topics: Acetylcysteine; Animals; Candida albicans; Candida glabrata; Candidiasis; Cell Death; Cell Line; Cell Nucleus; Free Radical Scavengers; Fungal Proteins; Gene Deletion; Gene Expression Regulation; GTP-Binding Proteins; Hepatocytes; Host-Pathogen Interactions; Humans; Hydroxyl Radical; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Peptides; Primary Cell Culture; Protein Glutamine gamma Glutamyltransferase 2; Saccharomyces cerevisiae; Signal Transduction; Transglutaminases

2017
Roles of intracellular and extracellular ROS formation in apoptosis induced by cold atmospheric helium plasma and X-irradiation in the presence of sulfasalazine.
    Free radical biology & medicine, 2018, Volume: 129

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Calcium; Caspase 3; Caspase 8; Cations, Divalent; Cell Line, Tumor; Cell Survival; DNA Fragmentation; fas Receptor; Gene Expression Regulation; HCT116 Cells; Helium; Humans; Hydroxyl Radical; Membrane Potential, Mitochondrial; Mitochondria; Oxidants; Oxidative Stress; Plasma Gases; Signal Transduction; Sulfasalazine; T-Lymphocytes; X-Rays

2018
l-Dehydroascorbic acid recycled by thiols efficiently scavenges non-thermal plasma-induced hydroxyl radicals.
    Archives of biochemistry and biophysics, 2019, 07-15, Volume: 669

    Topics: Acetylcysteine; Ascorbic Acid; Cyclic N-Oxides; Dehydroascorbic Acid; Dithiothreitol; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Hydroxyl Radical; Plasma Gases; Spin Labels

2019