acetylcysteine and homocysteine

acetylcysteine has been researched along with homocysteine in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.23)	18.7374
1990's	18 (22.22)	18.2507
2000's	35 (43.21)	29.6817
2010's	26 (32.10)	24.3611
2020's	1 (1.23)	2.80

Authors

Authors	Studies
Bakke, JE; Davison, KL; Larsen, GL	1
Eisenbart, J; Fless, GM; Hinman, J; Makino, K; Pfaffinger, D; Scanu, AM	1
Dekant, W; Henschler, D; Koob, M	1
Anders, MW; Dekant, W; Elfarra, AA; Henschler, D; Vamvakas, S	1
Elfarra, AA	1
Andersson, A; Hultberg, B; Larson, M; Masson, P; Tunek, A	1
Baraban, JM; Murphy, TH; Ratan, RR	1
Moog, C; Obert, G; Simon, G	1
Lock, EA	1
Bostom, AG; Fisher, DH; Nadeau, MR; Selhub, J; Shemin, D; Yoburn, D	1
Andersson, A; Fager, G; Hultberg, B; Lundstam, U; Masson, P; Wiklund, O	1
Andersson, A; Hultberg, B; Isaksson, A	4
Tyagi, SC	1
Barfuss, DW; Zalups, RK	1
Hoover-Plow, J; Skocir, P	1
Bernhard, MC; Hettinger, A; Junker, E; Lauterburg, BH	1
Frölich, JC; Gutzki, FM; Rossa, S; Sandmann, J; Tsikas, D	1
Panini, R; Pasini, MC; Salvioli, G; Scarpetta, G; Ventura, P	1
Kröning, R; Lichtenstein, AK; Nagami, GT	1
Chassaing, C; Gonin, J; Wainer, IW; Wilcox, CS	1
Abbracchio, MP; Camurri, A; Ceruti, S; Falzano, L; Fiorentini, C; Frank, C; Giammarioli, AM; Malorni, W; Rufini, S	1
Ovrebø, KK; Svardal, A	1
Bondy, SC; Campbell, A; Yang, EY	1
O, K; Siow, YL; Wang, G	1
Ashline, D; Collins, SC; Dhitavat, S; Ho, PI; Ortiz, D; Rogers, E; Shea, TB	1
Halliwell, B; Hua Long, L	1
Cole, DE; Evrovski, J; Forrest, Q; Holmes, K; Hutchison, SJ; Miner, SE; Ross, HJ	1
Peters, WH; Raijmakers, MT; Roes, EM; Steegers, EA	1
Huang, RF; Huang, SM; Hung, CY; Lin, BS; Lu, HT	1
Bostom, AG; Friedman, AN; Laliberty, P; Selhub, J; Shemin, D	1
Hultberg, B	1
Hak-Lemmers, HL; Peters, WH; Raijmakers, MT; Roes, EM; Schilders, GW; Steegers, EA; van Tits, LJ	1
Abbati, G; Marchetti, G; Panini, R; Salvioli, G; Ventura, P	1
Jara-Prado, A; Martinez-Ruano, L; Ortega-Vazquez, A; Rios, C; Santamaria, A	1
Blanco-Vaca, F; Cuquet, J; López, N; Mateo, J	1
Beige, J; Riezler, R; Rinder, C; Scholze, A; Tepel, M; Zidek, W	1
Robinson, K	1
Tepel, M; Zidek, W	1
Adams, C; Demirkol, O; Ercal, N	1
Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S	1
Cataldi, TR; Nardiello, D	1
Boo, TM; Merkus, HM; Peters, WH; Raijmakers, MT; Roes, EM; Steegers, EA; Zusterzeel, PL	1
Chang, T; Meng, QH; Wang, H; Wang, R; Wu, L; Yan, SK	1
Thaha, M; Tomino, Y; Yogiantoro, M	1
Campos, AC; Carneiro, CR; Correa, M; D'Almeida, V; Galdieri, LC; Jasiulionis, MG; Melo, FH; Molognoni, F	1
Capasso, R; De Santo, NG; Ingrosso, D; Lombardi, C; Luciano, MG; Perna, AF; Pulzella, P; Satta, E	1
Bolca, O; Cakmak, N; Nurkalem, Z; Onturk, E; Sahin, S; Sayar, N; Tangurek, B; Yilmaz, H; Yilmaz, M	1
Hsu, BG; Lee, RP; Subeq, YM; Tsai, WC; Wang, JH	1
Caccamo, D; Condello, S; Currò, M; Ferlazzo, N; Ientile, R; Parisi, G	1
Hughes, WM; Kumar, M; Kundu, S; Moshal, KS; Sen, U; Tyagi, N; Tyagi, SC; Vacek, TP	1
Birch, CS; Brasch, NE; McCaddon, A; Williams, JH	1
Hudson, PR; McCaddon, A	1
Cui, Y; Han, ZJ; Ma, X; Song, G; Xia, HF	1
Himmelfarb, J; McMenamin, ME; Nolin, TD; Ouseph, R; Ward, RA	1
Aleksandrowicz, E; Larczynski, W; Neuwelt, A; Renke, M; Rutkowski, B; Rutkowski, P; Tylicki, L; Łysiak-Szydłowska, W	1
Graalfs, H; Hofer, S; Horak, J; Lindner, W; Ronacher, A	1
Barnett, NW; Conlan, XA; Francis, PS; McDermott, GP; Terry, JM	1
Hsieh, CL; Peng, CC; Peng, RY; Tsai, WJ; Wang, HE	1
Abaterusso, C; Bellinghieri, G; Cirillo, G; Cirillo, M; Coppola, S; De Santo, NG; Di Iorio, B; Ingrosso, D; Lanza, D; Lupo, A; Perna, AF; Raiola, I; Raiola, P; Santoro, D; Satta, E; Savica, V; Sepe, I; Tirino, G; Violetti, E	1
Cacciapuoti, F	1
Gupta, S; Khandelwal, M; Manglani, K; Singh, RR; Surolia, A; Vijayan, V	1
Amar, E; Cohen, M; Cornet, D; Dattilo, M; Menezo, Y	1
Guo, XF; Tu, FQ; Wang, H; Wang, P; Zhang, HS; Zhang, LY	1
Birkner, E; Dobrakowski, M; Kasperczyk, A; Kasperczyk, S; Pawlas, N; Romuk, E; Rykaczewska-Czerwińska, M	1
Kanazawa, I; Notsu, M; Sugimoto, T; Takeno, A; Tanaka, K; Yamaguchi, T; Yokomoto, M	1
Battastini, AM; Bergamin, LS; Coutinho-Silva, R; de Souza Wyse, AT; Morrone, FB; Zanin, RF	1
Bonaterra, G; Dugi, KA; Edler, L; Hildebrandt, W; Kinscherf, R; Sauer, R	1
Elgawish, MS; Kishikawa, N; Kuroda, N	1
Adams, R; Erickson, CA; Klaunig, JE; McDougle, CJ; Plawecki, MH; Posey, DJ; Wang, Z; Wink, LK	1
Guo, X; Peng, Y; Sun, Y; Yao, T; Zheng, J	1
Gaifullina, AS; Hermann, A; Mustafina, AN; Sitdikova, GF; Weiger, TM; Yakovlev, AV	1
Aydın, AF; Doğru-Abbasoğlu, S; Kondakçı, G; Uysal, M	1
Andrejević, L; Cvetković, S; Djurić, D; Hrnčić, D; Jakovljević, V; Kostić, S; Labudović-Borović, M; Mićovic, Ž; Obrenović, R; Stamenković, A; Stanković, S	1
Borowczyk, K; Chwatko, G; Głowacki, R; Kamińska, A; Olejarz, P	1
Chen, TN; He, GW; Hou, HT; Wang, J; Wang, ZQ; Yang, Q; Zhang, JL; Zhang, X	1
Huang, CZ; Li, CM; Liu, JJ; Wang, J; Yan, HH; Yuan, D	1
Bloch, R; Brack, W; Krauss, M; Lehmann, I; Müller, E; Röder, S; Schütze, SE	1
Podsiadły, R; Romański, J; Świerczyńska, M; Słowiński, D	1

Reviews

3 review(s) available for acetylcysteine and homocysteine

Article	Year
Potential role of the flavin-containing monooxygenases in the metabolism of endogenous compounds. Chemico-biological interactions, 1995, Apr-28, Volume: 96, Issue:1 Topics: Acetylcysteine; Animals; Cysteine; Glutathione; Homocysteine; Mammals; Methionine; Oxidation-Reduction; Oxygenases; Sulfoxides	1995
N-Acetylcysteine in nephrology; contrast nephropathy and beyond. Current opinion in nephrology and hypertension, 2004, Volume: 13, Issue:6 Topics: Acetylcysteine; Antioxidants; Cardiovascular Diseases; Contrast Media; Homocysteine; Humans; Kidney Diseases; Kidney Failure, Chronic	2004
L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer's disease-related cognitive decline. CNS spectrums, 2010, Volume: 15, Issue:1 Suppl 1 Topics: Acetylcysteine; Alzheimer Disease; Cognition Disorders; Free Radical Scavengers; Homocysteine; Humans; Oxidative Stress; Plaque, Amyloid; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex	2010

Trials

19 trial(s) available for acetylcysteine and homocysteine

Article	Year
Lack of effect of oral N-acetylcysteine on the acute dialysis-related lowering of total plasma homocysteine in hemodialysis patients. Atherosclerosis, 1996, Volume: 120, Issue:1-2 Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Arteriosclerosis; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis	1996
N-acetylcysteine treatment lowers plasma homocysteine but not serum lipoprotein(a) levels. Atherosclerosis, 1996, Jan-05, Volume: 119, Issue:1 Topics: Acetylcysteine; Cross-Over Studies; Double-Blind Method; Female; Free Radical Scavengers; Homocysteine; Humans; Hyperlipoproteinemias; Lipoprotein(a); Male	1996
Time course of total cysteine, glutathione and homocysteine in plasma of patients with chronic hepatitis C treated with interferon-alpha with and without supplementation with N-acetylcysteine. Journal of hepatology, 1998, Volume: 28, Issue:5 Topics: Acetylcysteine; Adult; Antiviral Agents; Cysteine; Double-Blind Method; Female; Glutathione; Hepatitis C, Chronic; Homocysteine; Humans; Interferon-alpha; Male; Time Factors	1998
N-acetylcysteine neither lowers plasma homocysteine concentrations nor improves brachial artery endothelial function in cardiac transplant recipients. The Canadian journal of cardiology, 2002, Volume: 18, Issue:5 Topics: Acetylcysteine; Administration, Oral; Brachial Artery; Endothelium, Vascular; Female; Free Radical Scavengers; Heart Transplantation; Homocysteine; Humans; Male; Middle Aged; Treatment Outcome	2002
Effects of oral N-acetylcysteine on plasma homocysteine and whole blood glutathione levels in healthy, non-pregnant women. Clinical chemistry and laboratory medicine, 2002, Volume: 40, Issue:5 Topics: Acetylcysteine; Administration, Oral; Adult; Antioxidants; Dietary Supplements; Female; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia	2002
The effect of N-acetylcysteine on plasma total homocysteine levels in hemodialysis: a randomized, controlled study. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:2 Topics: Acetylcysteine; Administration, Oral; Aged; Dietary Supplements; Female; Homocysteine; Humans; Male; Middle Aged; Renal Dialysis; Vitamins	2003
N-Acetylcysteine improves the disturbed thiol redox balance after methionine loading. Clinical science (London, England : 1979), 2003, Volume: 105, Issue:2 Topics: Acetylcysteine; Adult; Antioxidants; Cross-Over Studies; Cysteine; Female; Homocysteine; Humans; Lipid Peroxidation; Male; Methionine; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sulfhydryl Compounds	2003
Urinary and plasma homocysteine and cysteine levels during prolonged oral N-acetylcysteine therapy. Pharmacology, 2003, Volume: 68, Issue:2 Topics: Acetylcysteine; Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Expectorants; Female; Homocysteine; Humans; Male; Middle Aged	2003
Acetylcysteine reduces plasma homocysteine concentration and improves pulse pressure and endothelial function in patients with end-stage renal failure. Circulation, 2004, Jan-27, Volume: 109, Issue:3 Topics: Acetylcysteine; Aged; Antioxidants; Blood Pressure; Cross-Over Studies; Endothelium, Vascular; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Vasodilation	2004
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia. Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3 Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation	2005
Oral N-acetylcysteine administration does not stabilise the process of established severe preeclampsia. European journal of obstetrics, gynecology, and reproductive biology, 2006, Volume: 127, Issue:1 Topics: Acetylcysteine; Administration, Oral; Adult; Antioxidants; Double-Blind Method; Female; Free Radical Scavengers; Glutathione; HELLP Syndrome; Homocysteine; Humans; Oxidative Stress; Pre-Eclampsia; Pregnancy; Regression Analysis; Treatment Outcome	2006
Intravenous N-acetylcysteine during haemodialysis reduces the plasma concentration of homocysteine in patients with end-stage renal disease. Clinical drug investigation, 2006, Volume: 26, Issue:4 Topics: Acetylcysteine; Adult; Aged; Blood Pressure; Blood Proteins; Diabetic Nephropathies; Drug Administration Schedule; Female; Heart Rate; Hematocrit; Homocysteine; Humans; Hypertension; Infusions, Intravenous; Kidney Calculi; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Treatment Outcome; Urticaria	2006
Effects of folic acid and N-acetylcysteine on plasma homocysteine levels and endothelial function in patients with coronary artery disease. Acta cardiologica, 2007, Volume: 62, Issue:6 Topics: Acetylcysteine; Administration, Oral; Aged; Coronary Artery Disease; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged	2007
Multiple-dose pharmacokinetics and pharmacodynamics of N-acetylcysteine in patients with end-stage renal disease. Clinical journal of the American Society of Nephrology : CJASN, 2010, Volume: 5, Issue:9 Topics: Acetylcysteine; Administration, Oral; Adult; Antioxidants; Area Under Curve; Biomarkers; Delayed-Action Preparations; Down-Regulation; Female; Half-Life; Homocysteine; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Oxidative Stress; Prospective Studies; Treatment Outcome; United States	2010
The effect of N-acetylcysteine on blood pressure and markers of cardiovascular risk in non-diabetic patients with chronic kidney disease: a placebo-controlled, randomized, cross-over study. Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:7 Topics: Acetylcysteine; Adolescent; Adult; Aged; Albuminuria; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cross-Over Studies; Diabetes Complications; Female; Free Radical Scavengers; Homocysteine; Humans; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Placebos; Proteins; Risk Factors; Sodium; Young Adult	2010
The importance of the one carbon cycle nutritional support in human male fertility: a preliminary clinical report. Reproductive biology and endocrinology : RB&E, 2014, Jul-29, Volume: 12 Topics: Acetylcysteine; Adult; Birth Rate; Dietary Supplements; Embryo Implantation; Family Characteristics; Female; Fertilization in Vitro; Fruit; Homocysteine; Humans; Infertility, Male; Insemination, Artificial, Homologous; Male; Middle Aged; Opuntia; Plant Extracts; Pregnancy; Pregnancy Rate; Switzerland; Vitamin B Complex; Vitamin E; Zinc	2014
Effect of N-acetylcysteine administration on homocysteine level, oxidative damage to proteins, and levels of iron (Fe) and Fe-related proteins in lead-exposed workers. Toxicology and industrial health, 2016, Volume: 32, Issue:9 Topics: Acetylcysteine; Adult; Air Pollutants, Occupational; Anemia, Iron-Deficiency; Antioxidants; Dietary Supplements; Haptoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Inhalation Exposure; Iron; Lead; Lead Poisoning; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Oxidative Stress; Poland; Protein Carbonylation; Protoporphyrins; Transferrin	2016
Oral N-acetylcysteine reduces plasma homocysteine concentrations regardless of lipid or smoking status. The American journal of clinical nutrition, 2015, Volume: 102, Issue:5 Topics: Acetylcysteine; Administration, Oral; Adult; Antihypertensive Agents; Antioxidants; Biotransformation; Cholesterol; Cysteine; Double-Blind Method; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Leukocytes, Mononuclear; Male; Middle Aged; Smoking; Triglycerides	2015
A randomized placebo-controlled pilot study of N-acetylcysteine in youth with autism spectrum disorder. Molecular autism, 2016, Volume: 7 Topics: Acetylcysteine; Administration, Oral; Autism Spectrum Disorder; Child; Child, Preschool; Comet Assay; DNA Damage; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Free Radical Scavengers; Glutathione; Homocysteine; Humans; Male; Oxidation-Reduction; Oxidative Stress; Pilot Projects; Placebo Effect; Social Behavior	2016

Other Studies

59 other study(ies) available for acetylcysteine and homocysteine

Article	Year
Comparative metabolism of the cysteine and homocysteine conjugates of propachlor by in situ perfused kidneys of rats. Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:4 Topics: Acetanilides; Acetylcysteine; Animals; Chemotherapy, Cancer, Regional Perfusion; Cysteine; Gas Chromatography-Mass Spectrometry; Herbicides; Homocysteine; Kidney; Rats; Rats, Inbred Strains	1992
Attenuation of immunologic reactivity of lipoprotein(a) by thiols and cysteine-containing compounds. Structural implications. Arteriosclerosis and thrombosis : a journal of vascular biology, 1992, Volume: 12, Issue:4 Topics: Acetylcysteine; Apolipoproteins A; Apolipoproteins B; Blotting, Western; Cysteine; Dithiothreitol; Enzyme-Linked Immunosorbent Assay; Homocysteine; Humans; Lipoprotein(a); Lipoproteins; Male; Mercaptoethanol; Molecular Structure; Sulfhydryl Compounds	1992
Metabolism of trichloroethene--in vivo and in vitro evidence for activation by glutathione conjugation. Chemico-biological interactions, 1990, Volume: 73, Issue:1 Topics: Acetylcysteine; Animals; Bile; Biotransformation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Male; Microsomes, Liver; Molecular Structure; Rats; Rats, Inbred Strains; Trichloroethylene	1990
Mutagenicity of amino acid and glutathione S-conjugates in the Ames test. Mutation research, 1988, Volume: 206, Issue:1 Topics: Acetylcysteine; Animals; Carbon-Sulfur Lyases; Cysteine; gamma-Glutamyltransferase; Glutathione; Homocysteine; Kidney; Liver; Lyases; Rats; Salmonella typhimurium; Structure-Activity Relationship	1988
Plasma homocysteine and thiol compound fractions after oral administration of N-acetylcysteine. Scandinavian journal of clinical and laboratory investigation, 1994, Volume: 54, Issue:6 Topics: Acetylcysteine; Homocysteine; Humans; Sulfhydryl Compounds	1994
Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:7 Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cells, Cultured; Cerebral Cortex; Cycloheximide; Cysteine; Glutamates; Glutathione; Homocysteine; Macromolecular Substances; Methionine Sulfoximine; Neurons; Oxidants; Protein Biosynthesis; Proteins; Rats	1994
Effects of glutathione precursors on human immunodeficiency virus replication. Chemico-biological interactions, 1994, Volume: 91, Issue:2-3 Topics: Acetylcysteine; beta-Galactosidase; Cell Line; Colorimetry; Gene Expression Regulation, Viral; Glutathione; Granulocyte-Macrophage Colony-Stimulating Factor; HIV; HIV Long Terminal Repeat; Homocysteine; Humans; Interleukin-6; Prodrugs; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Virus Replication	1994
Piggy-back race. Human & experimental toxicology, 1995, Volume: 14, Issue:11 Topics: Acetylcysteine; Animals; Binding, Competitive; Brain; Capillaries; Cells, Cultured; Cysteine; Endothelium, Vascular; Glutathione; Homocysteine; Leucine; Methylmercury Compounds; Penicillamine; Stereoisomerism; Sulfhydryl Compounds	1995
The effects of homocysteine and copper ions on the concentration and redox status of thiols in cell line cultures. Clinica chimica acta; international journal of clinical chemistry, 1997, Jun-27, Volume: 262, Issue:1-2 Topics: Acetylcysteine; Cell Line, Transformed; Copper; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; HeLa Cells; Homocysteine; Humans; Oxidation-Reduction; Sulfhydryl Compounds	1997
Homocysteine redox receptor and regulation of extracellular matrix components in vascular cells. The American journal of physiology, 1998, Volume: 274, Issue:2 Topics: Acetylcysteine; Actins; Amino Acid Sequence; Cell Division; Collagen; Extracellular Matrix Proteins; Free Radical Scavengers; Glutathione; Homocysteine; Homocystine; Humans; Molecular Sequence Data; Muscle, Smooth, Vascular; Oxidation-Reduction; Receptors, Cell Surface	1998
Participation of mercuric conjugates of cysteine, homocysteine, and N-acetylcysteine in mechanisms involved in the renal tubular uptake of inorganic mercury. Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:4 Topics: Acetylcysteine; Analysis of Variance; Animals; Biological Transport; Cysteine; Disease Models, Animal; Drug Interactions; Feces; Homocysteine; Kidney; Kidney Tubules, Proximal; Ligation; Liver; Male; Mercury; Normal Distribution; Rats; Rats, Sprague-Dawley; Reference Values; Ureter; Urine	1998
Enzymatic and chemical modifications of lipoprotein(a) selectively alter its lysine-binding functions. Biochimica et biophysica acta, 1998, May-20, Volume: 1392, Issue:1 Topics: Acetylcysteine; Amidines; Binding Sites; Chromatography, Affinity; Copper Sulfate; Homocysteine; Immunoassay; Lipoprotein(a); Lysine; Oxidation-Reduction; Phospholipases A; Phospholipases A2	1998
Investigations of S-transnitrosylation reactions between low- and high-molecular-weight S-nitroso compounds and their thiols by high-performance liquid chromatography and gas chromatography-mass spectrometry. Analytical biochemistry, 1999, Jun-01, Volume: 270, Issue:2 Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Cysteine; Erythrocytes; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Humans; Hydroxylamine; In Vitro Techniques; Kinetics; Molecular Weight; Nitric Oxide; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Sulfhydryl Compounds	1999
N -Acetyl-cysteine reduces homocysteine plasma levels after single intravenous administration by increasing thiols urinary excretion. Pharmacological research, 1999, Volume: 40, Issue:4 Topics: Acetylcysteine; Aged; Aged, 80 and over; Cysteine; Female; Free Radical Scavengers; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged	1999
Sulfur-containing amino acids decrease cisplatin cytotoxicity and uptake in renal tubule epithelial cell lines. Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:1 Topics: Acetylcysteine; Amino Acids; Animals; Antineoplastic Agents; Cisplatin; Cysteine; Homocysteine; Humans; Kidney Tubules; Methionine; Mice; Tumor Cells, Cultured	2000
Determination of reduced and oxidized homocysteine and related thiols in plasma by thiol-specific pre-column derivatization and capillary electrophoresis with laser-induced fluorescence detection. Journal of chromatography. B, Biomedical sciences and applications, 1999, Dec-10, Volume: 735, Issue:2 Topics: Acetylcysteine; Electrophoresis, Capillary; Glutathione; Homocysteine; Humans; Lasers; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence	1999
Adenosine- and 2-chloro-adenosine-induced cytopathic effects on myoblastic cells and myotubes: involvement of different intracellular mechanisms. Neuromuscular disorders : NMD, 2000, Volume: 10, Issue:6 Topics: 2-Chloroadenosine; Acetylcysteine; Actin Cytoskeleton; Adenosine; Adenosine Kinase; Animals; Apoptosis; Cell Adhesion; Cell Line; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Homocysteine; Intracellular Fluid; Mice; Microscopy, Electron, Scanning; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Thioinosine; Tubercidin	2000
The effect of glutathione modulation on the concentration of homocysteine in plasma of rats. Pharmacology & toxicology, 2000, Volume: 87, Issue:3 Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Chromatography, Liquid; Enzyme Inhibitors; Expectorants; Fasting; Glutathione; Hemodynamics; Homocysteine; Male; Rats; Rats, Wistar; Sulfhydryl Compounds	2000
Configuration of thiols dictates their ability to promote iron-induced reactive oxygen species generation. Redox report : communications in free radical research, 2000, Volume: 5, Issue:6 Topics: Acetylcysteine; Animals; Antioxidants; Cerebral Cortex; Cysteine; Glutathione; Homocysteine; Indicators and Reagents; Iron; Male; Mice; Mice, Inbred Strains; Mitochondria; Oxidation-Reduction; Reactive Oxygen Species; Structure-Activity Relationship; Sulfhydryl Compounds; Synaptosomes	2000
Interaction of metals and thiols in cell damage and glutathione distribution: potentiation of mercury toxicity by dithiothreitol. Toxicology, 2001, Jan-02, Volume: 156, Issue:2-3 Topics: Acetylcysteine; Antioxidants; Copper; Dithiothreitol; Drug Synergism; Glutathione; HeLa Cells; Homocysteine; Humans; Hydrogen Peroxide; Hydroquinones; Mercury; Oxidation-Reduction; Sodium Selenite	2001
Thiol redox status influences extracellular concentration of homocysteine in HeLa cell cultures. Clinical chemistry and laboratory medicine, 2000, Volume: 38, Issue:12 Topics: Acetylcysteine; Copper; Dithiothreitol; Dose-Response Relationship, Drug; HeLa Cells; Homocysteine; Humans; Indicators and Reagents; Ions; Oxidation-Reduction; Oxygen; Phenanthrolines; Sulfhydryl Compounds	2000
Homocysteine induces monocyte chemoattractant protein-1 expression by activating NF-kappaB in THP-1 macrophages. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6 Topics: Acetylcysteine; Antibodies; Binding, Competitive; Cell Line; Chemokine CCL2; Chemotaxis; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression; Homocysteine; Humans; I-kappa B Proteins; Macrophages; NF-kappa B; NF-KappaB Inhibitor alpha; RNA, Messenger; RNA, Ribosomal, 28S; Tosyllysine Chloromethyl Ketone	2001
Homocysteine potentiates beta-amyloid neurotoxicity: role of oxidative stress. Journal of neurochemistry, 2001, Volume: 78, Issue:2 Topics: Acetylcysteine; Amyloid beta-Peptides; Apoptosis; Calcium; Cell Differentiation; Cytosol; Drug Synergism; Free Radical Scavengers; Homocysteine; Humans; Neuroblastoma; Neurotoxins; Oxidative Stress; Peptide Fragments; Phosphatidylserines; Reactive Oxygen Species; Tumor Cells, Cultured; Vitamin E	2001
Oxidation and generation of hydrogen peroxide by thiol compounds in commonly used cell culture media. Biochemical and biophysical research communications, 2001, Sep-07, Volume: 286, Issue:5 Topics: Acetylcysteine; Animals; Cattle; Cell Culture Techniques; Culture Media; Cysteamine; Cysteine; Dipeptides; Dose-Response Relationship, Drug; Electrophysiology; Free Radical Scavengers; Glutathione; Homocysteine; Hydrogen Peroxide; Oxidation-Reduction; Sulfhydryl Compounds	2001
Lipoic acid increases glutathione production and enhances the effect of mercury in human cell lines. Toxicology, 2002, Jun-14, Volume: 175, Issue:1-3 Topics: Acetylcysteine; Antioxidants; Dithiothreitol; Drug Synergism; Glutathione; HeLa Cells; Hepatocytes; Homocysteine; Humans; Mercury; Thioctic Acid	2002
N-Acetylcysteine, vitamin C and vitamin E diminish homocysteine thiolactone-induced apoptosis in human promyeloid HL-60 cells. The Journal of nutrition, 2002, Volume: 132, Issue:8 Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Folic Acid; HL-60 Cells; Homocysteine; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Vitamin E	2002
Modulation of extracellular homocysteine concentration in human cell lines. Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 330, Issue:1-2 Topics: Acetylcysteine; Amino Acid Transport Systems; Carcinoma, Hepatocellular; Copper; Cysteine; Dithiothreitol; Extracellular Fluid; HeLa Cells; Homocysteine; Humans; Oxidation-Reduction; Sulfhydryl Compounds; Sulfonic Acids; Tumor Cells, Cultured	2003
Homocysteine-induced brain lipid peroxidation: effects of NMDA receptor blockade, antioxidant treatment, and nitric oxide synthase inhibition. Neurotoxicity research, 2003, Volume: 5, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Homocysteine; Indazoles; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thiobarbituric Acid Reactive Substances	2003
Patient presenting multiple consecutive venous and arterial thrombotic events despite intensive conventional treatment: response after normalization of plasma homocysteine and N-acetylcysteine therapy. Journal of internal medicine, 2003, Volume: 254, Issue:4 Topics: Acetylcysteine; Fatal Outcome; Fibrinolytic Agents; Homocysteine; Humans; Male; Middle Aged; Pulmonary Embolism; Streptokinase; Thrombosis; Venous Thrombosis	2003
Renal disease, homocysteine, and cardiovascular complications. Circulation, 2004, Jan-27, Volume: 109, Issue:3 Topics: Acetylcysteine; Antioxidants; Cardiovascular Diseases; Homocysteine; Humans; Kidney Failure, Chronic; Risk Factors	2004
Biologically important thiols in various vegetables and fruits. Journal of agricultural and food chemistry, 2004, Dec-29, Volume: 52, Issue:26 Topics: Acetylcysteine; Captopril; Chromatography, High Pressure Liquid; Cysteine; Fruit; Homocysteine; Sulfhydryl Compounds; Vegetables	2004
A pulsed potential waveform displaying enhanced detection capabilities towards sulfur-containing compounds at a gold working electrode. Journal of chromatography. A, 2005, Feb-25, Volume: 1066, Issue:1-2 Topics: Acetylcysteine; Biotin; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Cystine; Electrochemistry; Electrodes; Glutathione; Gold; Homocysteine; Methionine; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Sulfur Compounds; Thioctic Acid	2005
Effects of hydrogen sulfide on homocysteine-induced oxidative stress in vascular smooth muscle cells. Biochemical and biophysical research communications, 2006, Dec-15, Volume: 351, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Line; Glutathione; Homocysteine; Hydrogen Sulfide; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Onium Compounds; Oxidative Stress; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Sulfides; Superoxide Dismutase; Superoxides	2006
Oxidative stress modulates DNA methylation during melanocyte anchorage blockade associated with malignant transformation. Neoplasia (New York, N.Y.), 2007, Volume: 9, Issue:12 Topics: Acetylcysteine; Animals; Anoikis; Cell Adhesion; Cell Culture Techniques; Cell Transformation, Neoplastic; Cells, Cultured; Cysteine; DNA Methylation; Gene Expression Regulation; Glutathione; Homocysteine; Lipid Peroxidation; Melanocytes; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Sepharose; Superoxides; Trypsin	2007
Is homocysteine toxic in uremia? Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2008, Volume: 18, Issue:1 Topics: Acetylcysteine; Antitoxins; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Myocardial Infarction; Recurrence; Reference Values; Renal Dialysis; Retrospective Studies; Risk Factors; Uremia	2008
Intravenous N-acetylcysteine with saline hydration improves renal function and ameliorates plasma total homocysteine in patients undergoing cardiac angiography. Renal failure, 2008, Volume: 30, Issue:5 Topics: Acetylcysteine; C-Reactive Protein; Coronary Angiography; Creatinine; Glomerular Filtration Rate; Homocysteine; Humans; Injections, Intravenous; Interleukin-10; Kidney; Osmotic Fragility; Tumor Necrosis Factor-alpha	2008
NF-kappaB activation is associated with homocysteine-induced injury in Neuro2a cells. BMC neuroscience, 2008, Jul-07, Volume: 9 Topics: Acetylcysteine; alpha-Tocopherol; Animals; Apoptosis; bcl-2-Associated X Protein; Benzofurans; Blotting, Western; Caspase 3; Cell Differentiation; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Free Radical Scavengers; Homocysteine; Mitochondria; Neuroblastoma; NF-kappa B; Peptides; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tumor Suppressor Protein p53; Vitamin E	2008
H2S protects against methionine-induced oxidative stress in brain endothelial cells. Antioxidants & redox signaling, 2009, Volume: 11, Issue:1 Topics: Acetophenones; Acetylcysteine; Animals; Brain; Catalase; Cell Line, Transformed; Cell Survival; Dose-Response Relationship, Drug; Endothelial Cells; Formazans; Glutathione; Homocysteine; Hydrogen Sulfide; Methionine; Mice; Models, Biological; NG-Nitroarginine Methyl Ester; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Time Factors	2009
A novel role for vitamin B(12): Cobalamins are intracellular antioxidants in vitro. Free radical biology & medicine, 2009, Jul-15, Volume: 47, Issue:2 Topics: Acetylcysteine; Antioxidants; Cell Line; Cell Survival; Cysteine; Glutathione; Homocysteine; Humans; Hydrogen Peroxide; Oxidative Stress; Reactive Oxygen Species; Vitamin B 12; Vitamin B Complex	2009
Protective effects of N-acetylcysteine on homocysteine induced injury in chick embryos. Frontiers in bioscience (Elite edition), 2010, 06-01, Volume: 2, Issue:3 Topics: Acetylcysteine; Animals; Cell Line; Chick Embryo; Embryo, Nonmammalian; Homocysteine; In Situ Nick-End Labeling; Rats; Reactive Oxygen Species	2010
Static and dynamic binding capacities of human immunoglobulin G on polymethacrylate based mixed-modal, thiophilic and hydrophobic cation exchangers. Journal of chromatography. A, 2011, Dec-09, Volume: 1218, Issue:49 Topics: Acetylcysteine; Adsorption; Animals; Antibodies, Monoclonal; Cations; Cells, Cultured; CHO Cells; Chromatography, Ion Exchange; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Homocysteine; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Immunoglobulin G; Ion Exchange Resins; Ligands; Poloxamer; Polymethacrylic Acids; Protein Binding; Silver Staining; Sodium Chloride	2011
Direct detection of biologically significant thiols and disulfides with manganese(IV) chemiluminescence. Analytical chemistry, 2011, Aug-01, Volume: 83, Issue:15 Topics: Acetylcysteine; Adult; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Cystine; Disulfides; Female; Glutathione; Glutathione Disulfide; Homocysteine; Homocystine; Humans; Luminescent Measurements; Male; Manganese; Oxidative Stress; Sulfhydryl Compounds; Young Adult	2011
Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, and N-acetylcysteine in chicken embryo model. Toxicology, 2012, Jan-27, Volume: 291, Issue:1-3 Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Ascorbic Acid; Chick Embryo; Chromatography, High Pressure Liquid; Folic Acid; Foot Deformities; Glutathione; Hindlimb; Histone Deacetylases; Homocysteine; Hydrogen Peroxide; Joints; Muscle, Skeletal; Neovascularization, Physiologic; Superoxide Dismutase; Teratogens; Tissue Embedding; Valproic Acid; Vitamins	2012
Therapy of hyperhomocysteinemia in hemodialysis patients: effects of folates and N-acetylcysteine. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2012, Volume: 22, Issue:5 Topics: Acetylcysteine; Aged; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis	2012
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:8 Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6	2012
Homocysteine alters the osteoprotegerin/RANKL system in the osteoblast to promote bone loss: pivotal role of the redox regulator forkhead O1. Free radical biology & medicine, 2013, Volume: 61 Topics: Acetylcysteine; Animals; Cells, Cultured; Female; Forkhead Transcription Factors; Homocysteine; Hyperhomocysteinemia; Nerve Tissue Proteins; Osteoblasts; Osteoporosis; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Protein Phosphatase 2; RANK Ligand; Rats; Rats, Sprague-Dawley	2013
A new BODIPY-based long-wavelength fluorescent probe for chromatographic analysis of low-molecular-weight thiols. Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:26 Topics: Acetylcysteine; Animals; Boron Compounds; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cysteine; Dipeptides; Fluorescent Dyes; Glutathione; Homocysteine; Iodoacetamide; Limit of Detection; Male; Mice; Penicillamine; Sulfhydryl Compounds	2014
Activation of AMP-activated protein kinase protects against homocysteine-induced apoptosis of osteocytic MLO-Y4 cells by regulating the expressions of NADPH oxidase 1 (Nox1) and Nox2. Bone, 2015, Volume: 77 Topics: Acetophenones; Acetylcysteine; AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Line; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Homocysteine; Membrane Glycoproteins; Mice; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; Osteocytes; Superoxide Dismutase	2015
Pathological concentrations of homocysteine increases IL-1β production in macrophages in a P2X7, NF-ĸB, and erk-dependent manner. Purinergic signalling, 2015, Volume: 11, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Homocysteine; Hyperhomocysteinemia; Interleukin-1beta; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Reactive Oxygen Species; Receptors, Purinergic P2X7; Toll-Like Receptor 4	2015
Quinones as novel chemiluminescent probes for the sensitive and selective determination of biothiols in biological fluids. The Analyst, 2015, Dec-21, Volume: 140, Issue:24 Topics: Acetylcysteine; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Fluorescent Dyes; Glutathione; Homocysteine; Humans; Limit of Detection; Luminescence; Molecular Structure; Quinones; Sulfhydryl Compounds	2015
Simultaneous assessment of endogenous thiol compounds by LC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Sep-01, Volume: 1029-1030 Topics: Acetylcysteine; Animals; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Glutathione; Homocysteine; Limit of Detection; Liver; Male; Mice; Reproducibility of Results; Sulfhydryl Compounds; Tandem Mass Spectrometry	2016
Homocysteine augments BK channel activity and decreases exocytosis of secretory granules in rat GH3 cells. FEBS letters, 2016, Volume: 590, Issue:19 Topics: Acetylcysteine; Action Potentials; Animals; Cell Line; Exocytosis; Homocysteine; Indoles; Large-Conductance Calcium-Activated Potassium Channels; Potassium Channel Blockers; Rats; Secretory Vesicles	2016
The effect of N-acetylcysteine supplementation on serum homocysteine levels and hepatic and renal oxidative stress in homocysteine thiolactone-treated rats. Archives of physiology and biochemistry, 2017, Volume: 123, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Dietary Supplements; Free Radical Scavengers; Glutathione; Homocysteine; Kidney; Kidney Function Tests; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Radiation-Protective Agents; Rats; Rats, Wistar	2017
The effects of L-cysteine and N-acetyl-L-cysteine on homocysteine metabolism and haemostatic markers, and on cardiac and aortic histology in subchronically methionine-treated Wistar male rats. Molecular and cellular biochemistry, 2019, Volume: 451, Issue:1-2 Topics: Acetylcysteine; Animals; Aorta; Biomarkers; Cysteine; Heart; Hemostatics; Homocysteine; Male; Methionine; Rats; Rats, Wistar	2019
Simultaneous determination of total homocysteine, cysteine, glutathione, and N-acetylcysteine in brain homogenates by HPLC. Journal of separation science, 2018, Volume: 41, Issue:16 Topics: Acetylcysteine; Animals; Brain; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Homocysteine; Swine	2018
Endothelial nitric oxide synthase enhancer AVE3085 reverses endothelial dysfunction induced by homocysteine in human internal mammary arteries. Nitric oxide : biology and chemistry, 2018, 12-01, Volume: 81 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Acetylcysteine; Benzodioxoles; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Indans; Mammary Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Organ Culture Techniques; Vasodilation; Vasodilator Agents	2018
Label-free gold nanorods sensor array for colorimetric detection and discrimination of biothiols in human urine samples. Talanta, 2019, Oct-01, Volume: 203 Topics: Acetylcysteine; Colorimetry; Cysteamine; Cysteine; Glutathione; Gold; Homocysteine; Humans; Nanotubes; Principal Component Analysis; Sulfhydryl Compounds	2019
Non-targeted mercapturic acid screening in urine using LC-MS/MS with matrix effect compensation by postcolumn infusion of internal standard (PCI-IS). Analytical and bioanalytical chemistry, 2019, Volume: 411, Issue:29 Topics: Acetylcysteine; Chromatography, Liquid; Homocysteine; Humans; Reference Standards; Tandem Mass Spectrometry	2019
HPLC Study of Product Formed in the Reaction of NBD-Derived Fluorescent Probe with Hydrogen Sulfide, Cysteine, Molecules (Basel, Switzerland), 2022, Nov-28, Volume: 27, Issue:23 Topics: Acetylcysteine; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Humans; Hydrogen Sulfide; Optical Imaging; Sulfhydryl Compounds	2022