acetylcysteine and hexachlorobutadiene

acetylcysteine has been researched along with hexachlorobutadiene in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Lock, EA; Pratt, IS1
Reichert, D; Schütz, S; Wild, D1
Reichert, D; Schütz, S1
Lock, EA; Odum, J; Ormond, P1
Ishmael, J; Lock, EA1
Hook, JB; Ishmael, J; Lock, EA1
Birner, G; Dekant, W; Werner, M1

Other Studies

8 other study(ies) available for acetylcysteine and hexachlorobutadiene

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Deacetylation and further metabolism of the mercapturic acid of hexachloro-1,3-butadiene by rat kidney cytosol in vitro.
    Archives of toxicology, 1988, Volume: 62, Issue:5

    Topics: Acetylation; Acetylcysteine; Aminooxyacetic Acid; Animals; Binding, Competitive; Butadienes; Cytosol; Female; Fungicides, Industrial; In Vitro Techniques; Kidney; Male; Rats; Rats, Inbred Strains; Sex Factors

1988
Mutagenicity of the mercapturic acid and other S-containing derivatives of hexachloro-1,3-butadiene.
    Carcinogenesis, 1986, Volume: 7, Issue:3

    Topics: Acetylcysteine; Butadienes; Glutathione; Liver; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Structure-Activity Relationship

1986
Mercapturic acid formation is an activation and intermediary step in the metabolism of hexachlorobutadiene.
    Biochemical pharmacology, 1986, Apr-15, Volume: 35, Issue:8

    Topics: Acetylcysteine; Animals; Biotransformation; Butadienes; Carbon Radioisotopes; Female; Gas Chromatography-Mass Spectrometry; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium

1986
Transport of N-acetyl-S-pentachloro-1,3-butadienylcysteine by rat renal cortex.
    Archives of toxicology, 1986, Volume: 59, Issue:1

    Topics: Acetylcysteine; Animals; Antimetabolites; Biological Transport, Active; Butadienes; Cysteine; Female; Kidney Cortex; Kinetics; Rats; Rats, Inbred Strains; Temperature

1986
Nephrotoxicity of hexachlorobutadiene and its glutathione-derived conjugates.
    Toxicologic pathology, 1986, Volume: 14, Issue:2

    Topics: Acetylcysteine; Animals; Butadienes; Cysteine; Female; Glutathione; Kidney Diseases; Kidney Medulla; Kidney Tubules, Proximal; Male; Necrosis; Rats; Sex Factors; Urea

1986
Nephrotoxicity of hexachloro-1,3-butadiene in the mouse: the effect of age, sex, strain, monooxygenase modifiers, and the role of glutathione.
    Toxicology and applied pharmacology, 1984, Mar-15, Volume: 72, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Aging; Animals; Butadienes; Female; Glutathione; Kidney Tubular Necrosis, Acute; Lethal Dose 50; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; p-Aminohippuric Acid; Sex Factors; Species Specificity; Tetraethylammonium; Tetraethylammonium Compounds; Urea

1984
The role of cytochrome P4503A1/2 in the sex-specific sulfoxidation of the hexachlorobutadiene metabolite, N-acetyl-S-(pentachlorobutadienyl)-L-cysteine in rats.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:8

    Topics: Acetylcysteine; Animals; Biotransformation; Butadienes; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Wistar; Sex Characteristics; Steroid Hydroxylases; Sulfoxides

1995