acetylcysteine and heme

acetylcysteine has been researched along with heme in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's4 (19.05)18.2507
2000's8 (38.10)29.6817
2010's6 (28.57)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Ignarro, LJ; Wood, KS1
Bailey, E; Campbell, JB; Farmer, PB; Nam, NH; Thang, DC; White, IN1
Osawa, Y; Williams, MS1
Behar, S; He, D; Lim, HW; Roberts, JE1
Bechara, EJ; Carvalho, H; Demasi, M; Meneghini, R1
Czyzyk-Krzeska, MF; Kroll, SL1
Foresti, R; Green, CJ; Hoque, M; Motterlini, R; Naughton, P1
Hu, Z; Lelli, KM; Maines, MD; Miralem, T; Torno, MD1
Monti, D; Montorfano, G; Omodeo Salè, F; Vanzulli, E1
Bingham, SA; Corpet, DE; Cross, AJ; Gasc, N; Gottardi, G; Guéraud, F; Peiro, G; Pierre, F; Taché, S1
Corpet, DE; Guéraud, F; Pierre, F; Santarelli, R; Taché, S1
Leite, MS; Meyer-Fernandes, JR; Oliveira, JH; Oliveira, PL; Thomaz, R1
Bumke, MA; ElSohly, MA; Galal, AM; Gul, W; Han, B; Hollingshead, MG; Newton, DL; Slade, D; Stockwin, LH; Yu, SX1
Chora, A; Coutinho, A; Ferreira, A; Gozzelino, R; Larsen, R; Penido, C; Rebelo, S; Seixas, E; Silva, G; Smith, NR; Soares, MP1
Liskova, J; Melkova, Z; Shankaran, P; Vlkova, L1
Chenni, FZ; Corpet, DE; Guéraud, F; Hobbs, DA; Kunhle, GG; Naud, N; Pierre, FH; Taché, S1
Green, J; Jesse, HE; Mann, BE; McLean, S; Nye, TL; Poole, RK1
Balaji, SN; Trivedi, V1
Ajioka, R; Cooksey, R; Cox, J; Gao, Y; Huang, J; Jones, D; Just, SF; King, D; Lee, SH; McClain, DA; Mitchell, TC; Simcox, JA1
Atella, GC; Coelho, MG; Cunha, PR; Justo, GA; Laranja, GA; Nogueira, NP; Paes, MC; Rossini, A; Sabino, KC; Saraiva, FM; Sultano, PE1
Annalora, AJ; Jefcoate, CR; Marcus, CB; Sheibani, N; Song, YS; Sorenson, CM1

Reviews

1 review(s) available for acetylcysteine and heme

ArticleYear
Cytochrome P450 1B1: A Key Regulator of Ocular Iron Homeostasis and Oxidative Stress.
    Cells, 2022, 09-20, Volume: 11, Issue:19

    Topics: Acetylcysteine; Antioxidants; Arachidonic Acid; Cytochrome P-450 Enzyme System; Endothelial Cells; Estradiol; Estrogens; Heme; Hepcidins; Homeostasis; Iron; Oxidative Stress; Polycyclic Aromatic Hydrocarbons; Reactive Oxygen Species; Trabecular Meshwork

2022

Trials

1 trial(s) available for acetylcysteine and heme

ArticleYear
New marker of colon cancer risk associated with heme intake: 1,4-dihydroxynonane mercapturic acid.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:11

    Topics: Acetylcysteine; Adult; Aged; Animal Feed; Animals; Biomarkers, Tumor; Colonic Neoplasms; Diet; Female; Heme; Humans; Iron; Male; Middle Aged; Oxidative Stress; Rats; Rats, Inbred F344; Risk

2006

Other Studies

19 other study(ies) available for acetylcysteine and heme

ArticleYear
Hepatic cyclic GMP formation is regulated by similar factors that modulate activation of purified hepatic soluble guanylate cyclase.
    The Journal of biological chemistry, 1987, Apr-15, Volume: 262, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Acetaminophen; Acetylcysteine; Animals; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Heme; Liver; Methylnitronitrosoguanidine; Mice; Nitroglycerin; Penicillamine; Phenobarbital; Phenylhydrazines; Potassium Cyanide; Probenecid; Protoporphyrins; Purinones; S-Nitroso-N-Acetylpenicillamine

1987
Metabolic activation of acetylenes. Covalent binding of [1,2-14C]octyne to protein, DNA and haem in vitro and the protective effects of certain thiol compounds.
    The Biochemical journal, 1984, May-15, Volume: 220, Issue:1

    Topics: Acetylcysteine; Alkynes; Animals; Chromatography, High Pressure Liquid; DNA; Heme; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Protein Binding; Proteins; Rats; Sulfhydryl Compounds

1984
Covalent crosslinking of the heme prosthetic group to myoglobin by H2O2: toxicological implications.
    Free radical biology & medicine, 1996, Volume: 21, Issue:1

    Topics: Acetylcysteine; Animals; Apoproteins; Binding Sites; Carbon Radioisotopes; Cell Death; Cell Line; Cross-Linking Reagents; Fibroblasts; Heme; Horses; Humans; Hydrogen Peroxide; Myoglobin; Oxidoreductases; Protein Binding; Radioisotope Dilution Technique

1996
The effect of L-cysteine and N-acetylcysteine on porphyrin/heme biosynthetic pathway in cells treated with 5-aminolevulinic acid and exposed to radiation.
    Photodermatology, photoimmunology & photomedicine, 1996, Volume: 12, Issue:5

    Topics: Acetylcysteine; Aminolevulinic Acid; Cells, Cultured; Cysteine; Endothelium, Vascular; Ferrochelatase; Heme; Humans; Porphyrins; Ultraviolet Rays

1996
Haem precursor delta-aminolaevulinic acid induces activation of the cytosolic iron regulatory protein 1.
    The Biochemical journal, 1997, Dec-15, Volume: 328 ( Pt 3)

    Topics: Acetylcysteine; Aminolevulinic Acid; Animals; Cell Line; Cricetinae; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Ferritins; Heme; Homeostasis; Iron; Iron Regulatory Protein 1; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Lung; Oxidation-Reduction; Porphobilinogen Synthase; Reactive Oxygen Species; RNA-Binding Proteins; RNA, Messenger

1997
Role of H2O2 and heme-containing O2 sensors in hypoxic regulation of tyrosine hydroxylase gene expression.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Acetylcysteine; Actins; Amitrole; Animals; Antioxidants; Biosensing Techniques; Catalase; Cell Hypoxia; Deferoxamine; Gene Expression Regulation, Enzymologic; Heme; Hydrogen Peroxide; Kinetics; Oxygen; PC12 Cells; Rats; RNA, Messenger; Tiopronin; Transcription, Genetic; Tyrosine 3-Monooxygenase

1998
Interaction of heme with nitroxyl or nitric oxide amplifies heme oxygenase-1 induction: involvement of the transcription factor Nrf2.
    Cellular and molecular biology (Noisy-le-Grand, France), 2002, Volume: 48, Issue:8

    Topics: Acetylcysteine; Animals; Anions; Blotting, Western; Cell Line; Cell Survival; DNA-Binding Proteins; Dose-Response Relationship, Drug; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Myocardium; NF-E2-Related Factor 2; Nitric Oxide; Nitrogen; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Protein Binding; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sulfhydryl Compounds; Temperature; Time Factors; Trans-Activators

2002
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells.
    The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17

    Topics: Acetylcysteine; Apoptosis; Apoptosis Regulatory Proteins; Arsenites; Biliverdine; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Cytochromes c; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Silencing; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Luciferases; Membrane Glycoproteins; Membrane Proteins; Oligonucleotides; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Phosphorylation; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Protein Binding; Protein Biosynthesis; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Retroviridae; RNA, Messenger; RNA, Small Interfering; Serine; Sodium Compounds; Threonine; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor AP-1; Transfection; Tumor Necrosis Factor-alpha

2005
Major artifacts encountered in studying biological samples containing ferric protoporphyrin IX.
    Analytical biochemistry, 2005, Apr-15, Volume: 339, Issue:2

    Topics: Acetylcysteine; Arachidonic Acid; Artifacts; Cell Membrane; Erythrocyte Membrane; Freezing; Heme; Lipid Peroxidation; Membrane Lipids; Micelles; Proteins; Solubility

2005
Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium.
    The British journal of nutrition, 2008, Volume: 99, Issue:5

    Topics: 1,2-Dimethylhydrazine; Acetylcysteine; Animals; Antioxidants; Body Weight; Calcium, Dietary; Cattle; Cell Transformation, Neoplastic; Colorectal Neoplasms; Diet; Eating; Feces; Female; Heme; Meat; Olive Oil; Plant Oils; Rats; Rats, Inbred F344; Thiobarbituric Acid Reactive Substances

2008
Trypanosoma brucei brucei: effects of ferrous iron and heme on ecto-nucleoside triphosphate diphosphohydrolase activity.
    Experimental parasitology, 2009, Volume: 121, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Ferrous Compounds; Heme; Lipid Peroxidation; Magnesium; Polyethylene Glycols; Pyrophosphatases; Reactive Oxygen Species; Trypanosoma brucei brucei; Xanthurenates

2009
Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.
    International journal of cancer, 2009, Sep-15, Volume: 125, Issue:6

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Artemisia; Artemisinins; Biomarkers; Blotting, Western; Calcium; Cell Cycle; Dimerization; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Profiling; Heme; Heme Oxygenase-1; Humans; Lysine; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin

2009
Heme oxygenase-1 affords protection against noncerebral forms of severe malaria.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Sep-15, Volume: 106, Issue:37

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Gene Expression; Heme; Heme Oxygenase-1; Hepatocytes; Liver Failure; Malaria; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Knockout; Mice, SCID; Oxidative Stress; Plasmodium chabaudi; Transplantation Chimera; Tumor Necrosis Factor-alpha

2009
Heme arginate potentiates latent HIV-1 reactivation while inhibiting the acute infection.
    Antiviral research, 2011, Volume: 92, Issue:3

    Topics: Acetylcysteine; Anti-HIV Agents; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Arginine; Cell Line; Heme; Heme Oxygenase-1; HIV-1; Humans; Jurkat Cells; Lectins, C-Type; Metalloporphyrins; Protoporphyrins; Proviruses; Reverse Transcription; Virus Activation; Virus Latency; Virus Replication

2011
Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite.
    Nutrition and cancer, 2013, Volume: 65, Issue:2

    Topics: Acetylcysteine; Animals; Biomarkers; Body Weight; Colonic Neoplasms; Disease Models, Animal; Drinking Water; Eating; Feces; Heme; Lipid Peroxidation; Male; Meat; Nitrites; Nitroso Compounds; Rats, Inbred F344; Saliva; Sodium Nitrite; Thiobarbituric Acid Reactive Substances

2013
Cytochrome bd-I in Escherichia coli is less sensitive than cytochromes bd-II or bo'' to inhibition by the carbon monoxide-releasing molecule, CORM-3: N-acetylcysteine reduces CO-RM uptake and inhibition of respiration.
    Biochimica et biophysica acta, 2013, Volume: 1834, Issue:9

    Topics: Acetylcysteine; Antioxidants; Carbon Monoxide; Cell Membrane; Cell Respiration; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Hyperbaric Oxygenation; Leghemoglobin; Organometallic Compounds; Oxidoreductases; Oxygen Consumption; Ruthenium

2013
Suicidal inactivation of methemoglobin by generation of thiyl radical: insight into NAC mediated protection in RBC.
    Current molecular medicine, 2013, Volume: 13, Issue:6

    Topics: Acetylcysteine; Cytoprotection; Erythrocytes; Free Radicals; Heme; Hemolysis; Humans; Hydrogen Peroxide; Kinetics; Methemoglobin; Oxidation-Reduction; Oxidative Stress; Peroxidase; Piperidines; Protective Agents; Spectrometry, Mass, Electrospray Ionization

2013
Dietary iron controls circadian hepatic glucose metabolism through heme synthesis.
    Diabetes, 2015, Volume: 64, Issue:4

    Topics: Acetylcysteine; Aminolevulinic Acid; Animals; Antioxidants; Circadian Rhythm; Gluconeogenesis; Glucose; Heme; Hep G2 Cells; Humans; Iron, Dietary; Liver; Male; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Transcription Factors

2015
Proliferation and differentiation of Trypanosoma cruzi inside its vector have a new trigger: redox status.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Cycle; Cell Proliferation; Heme; Hydrogen Peroxide; Insect Vectors; Oxidation-Reduction; Rhodnius; Trypanosoma cruzi; Uric Acid

2015