acetylcysteine and glutathione disulfide

acetylcysteine has been researched along with glutathione disulfide in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-19905 (4.39)18.7374
1990's28 (24.56)18.2507
2000's46 (40.35)29.6817
2010's31 (27.19)24.3611
2020's4 (3.51)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Asensi, M; Estrela, JM; Hernandez, R; Puertes, IR; Terradez, P; Viña, J1
Bast, A; Haenen, GR1
Moldéus, P; Norbeck, K; Ross, D1
Joshi, UM; Kodavanti, PR; Mehendale, HM1
Eckert, KG; Issels, RD; Nagele, A; Wilmanns, W1
Bennicelli, C; Camoirano, A; De Flora, A; De Flora, S; Morelli, A; Zanacchi, P1
Corcoran, GB; Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV1
Flecks, U; Larsen, R; Marzi, I; Walcher, F1
Ciufo, R; DiMarco, A; Stofan, D; Supinski, GS1
Bockstette, M; Dröge, W; Fischbach, T; Galter, D; Gmünder, H; Kinscherf, R; Mihm, S; Roth, S1
Albini, A; Balansky, R; D'Agostini, F; De Flora, S; Giunciuglio, D; Paglieri, I1
Dröge, W; Galter, D; Mihm, S1
Asensi, M; Pallardó, FV; Rodrigo, F; Sastre, J; Vento, M; Viña, J1
Beehler, CJ; Hybertson, BM; Leff, JA; Repine, JE; Shanley, PF; Wilke, CP1
Slaga, TJ; Warren, BS1
Boily, MJ; Brunet, J; Cordeau, S; Des Rosiers, C1
Kawase, M; Kinoshita, C; Murata, H; Nakata, K; Ogata, K; Ogino, S; Ohmori, S; Sakaue, T1
Aoki, T; Fujita, H; Miyata, A; Mori, M; Nishio, K; Oyamada, Y; Suzuki, K; Suzuki, Y; Yamaguchi, K1
De La Motte, C; DiCorleto, PE; Faruqi, RM; Faruqi, TR; Poptic, EJ1
Behr, J; Degenkolb, B; Krombach, F; Maier, K; Vogelmeier, C1
Hayase, Y; Kashiwakura, I; Kuwabara, M; Murakami, M; Takagi, Y1
Berns, CM; Chen, JC; Corry, PM; Davis, BH; Galoforo, SS; Lee, YJ; Sim, JE; Spitz, DR1
Brakenhoff, JP; Commandeur, JN; Groot, EJ; Li, QJ; Ramnatshing, S; Vermeulen, NP; Wormhoudt, LW1
Barton, S; Kaiser, R; Kupfer, B; Lemoch, H; Look, MP; Rao, GS; Rockstroh, JK; Sauerbruch, T; Spengler, U; Sudhop, T1
Khan, M; Pahan, K; Singh, AK; Singh, I1
Armiento, A; Bravi, MC; Cassone-Faldetta, M; De Luca, O; De Mattia, G; Ferri, C; Laurenti, O; Proietti, A1
Brigelius-Flohé, R; Friedrichs, B; Müller, C1
Cooper, K; Ercal, N; Gurer, H; Neal, R1
Fanburg, BL; Lanzillo, JJ; Lee, SL; Maloney, EK; White, AC1
Ertel, W; Hentze, H; Künstle, G; Volbracht, C; Wendel, A1
Brown, LA; Guidot, DM; Lois, M; Moss, IM; Roman, J1
Caffrey, JL; Mallet, RT; Sun, J; Tejero-Taldo, MI1
Huyck, HL; Khalak, R; Pryhuber, GS1
Conti, A; De Gaudio, AR; Masoni, M; Novelli, G; Ortolani, O1
Chen, G; Wang, SH; Warner, TD1
Haddad, JJ; Land, SC; Olver, RE1
Fujiwara, Y; Hatakeyama, T; Jaeck, D; Kitamura, N; Kumada, K; Matsumiya, A; Nakano, H; Sakai, H; Yamaguchi, M1
Chipman, JK; Parsons, JL1
Agustí, AG; Busquets, X; Hussain, S; MacNee, W; Miralles, C; Rahman, I; Santos, C; Togores, B1
Chung, HY; Han, SI; Kang, HS; Kim, HD; Kim, SH; Oh, SY1
Davies, KJ; Demasi, M; Shringarpure, R1
Bravo, E; Cantafora, A; Napolitano, M; Rivabene, R1
Aihara, M; Araki, T; Dobashi, K; Hamuro, J; Iizuka, K; Mori, M; Murata, Y; Nakazawa, T; Shimizu, Y; Utsugi, M1
Besner, JG; Bouchard, JF; Cabassi, A; de Champlain, J; Dumont, EC; Girouard, H; Lamontagne, D; Le Jossec, M1
Boget, S; Cereser, C; Parvaz, P; Revol, A1
Aw, TY; Fujimoto, K; Iwakiri, R; Noda, T1
Agapito, MT; González, C; Obeso, A; Sanz-Alfayate, G1
Haddad, JJ2
Aw, TY; Pias, EK1
Aw, TY; Fujimoto, K; Gotoh, Y; Iwakiri, R; Noda, T; Rhoads, CA1
Fisher, JC; Kinane, TB; Kling, DE; Schnitzer, JJ1
Fernandez, V; Israel, Y; Tapia, G; Videla, LA1
Chuujou, H; Iwasaki, K; Kitazawa, M; Nakano, T; Sakamoto, K; Shiojiri, E1
Bjorksten, AR; Brown, MJ; Leppik, JA; McKenna, MJ; Medved, I; Sostaric, S1
Albertazzi, A; Bellei, E; Bergamini, S; Iannone, A; Manfredini, P; Rota, C; Tomasi, A1
Aiba, S; Mizuashi, M; Nakagawa, S; Ohtani, T1
Aw, TY; Ekshyyan, O1
Aykin-Burns, N; Ercal, N; Franklin, EA1
Jannis, NC; Lerut, TE; Neyrinck, AP; Rega, FR; Van Raemdonck, DE; Vanaudenaerde, BM; Verleden, GM; Wuyts, WA1
Dwarte, TM; Luty, A; Raftos, JE; Willcock, CJ1
Banks, WA; Ercal, N; Price, TO; Uras, F1
Hales, BF; Sahambi, SK1
Ibi, M; Iwata, K; Kakehi, T; Katsuyama, M; Matsuno, K; Nishinaka, T; Yabe-Nishimura, C1
Chang, LW; Cheng, LC; Cheng, Y; Lin, P; Tsai, MH1
Pat, SW; Yang, MS; Yu, LC1
Doneanu, CE; Niture, SK; Pattabiraman, N; Srivenugopal, KS; Velu, CS1
Benavides, GA; Darley-Usmar, VM; Doeller, JE; Isbell, TS; Kraus, DW; Mills, RW; Patel, HD; Patel, RP; Squadrito, GL1
Carlsson, T; Karlsson, JO; Petersen, A; Zetterberg, M1
Aw, TY; Circu, ML; Maloney, R; Moyer, MP; Rodriguez, C1
Demrkol, O1
Chen, J; Shen, J; Wang, C; Zhang, D; Zhang, X1
Agapito, MT; Gomez-Niño, A; Gonzalez, C; Obeso, A1
Chen, W; Guan, X; Hu, Y; Matthees, D; Seefeldt, T; Wang, X; Zhao, Y1
Aronstam, RS; Ercal, N; Huang, CC; Huang, YW; Martin, A; Shi, R1
Kurashima, Y; Ogura, T; Sakagami, H; Sugiyama, K; Tajima, M1
Carlson, L; Chen, W; Foll, R; Guan, X; Hanson, S; Matthees, DP; Palakurthi, S; Seefeldt, T; Stoebner, A; Zhao, Y1
Ferreira, LF; Gilliam, LA; Reid, MB1
Aquaro, S; Biasin, A; Del Duca, C; Granato, T; Masuelli, L; Mollace, V; Muscoli, C; Perno, CF; Pollicita, M; Rodinò, P; Sgura, A; Tanzarella, C1
Beckmann, B; Dehnert, S; Giustarini, D; Michaelsen, JT; Tsikas, D1
Banerjee, A; Banks, WA; Ercal, N; Manda, KR; Zhang, X1
Britz-McKibbin, P; Lee, R; Phillips, SM; West, D1
Moldobaeva, A; Nijmeh, J; Wagner, EM1
Acharya, M; Lau-Cam, CA2
Borisenko, GG; Demina, IA; Galyamina, MA; Govorun, VM; Lazarev, VN; Levitskiy, SA; Serebryakova, MV; Shkarupeta, MM1
Lima, CF; Pereira-Wilson, C; Rattan, SI1
Ercal, N; Penugonda, S1
Grosicka-Maciąg, E; Grzela, T; Kurpios-Piec, D; Rahden-Staroń, I; Szumiło, M1
Karayakar, F; Karaytug, S; Sevgiler, Y1
Barnett, NW; Conlan, XA; Francis, PS; McDermott, GP; Terry, JM1
Catarzi, S; Favilli, F; Iantomasi, T; Marcucci, T; Picariello, L; Romagnoli, C; Tonelli, F; Vincenzini, MT1
Asress, SA; Fischer, LR; Glass, JD; Jones, DP; Li, Y1
Benjamin, IJ; Christians, E; Limphong, P; Liu, Q; Pieper, J; Rodesch, CK; Zhang, H1
Cottalasso, D; Domenicotti, C; Furfaro, AL; Marengo, B; Marinari, UM; Nitti, M; Pronzato, MA; Traverso, N1
Cameán, AM; Gutiérrez-Praena, D; Jos, Á; Pichardo, S; Prieto, AI; Puerto, M; Vasconcelos, V1
Brandi, ML; Favilli, F; Galli, G; Iantomasi, T; Marcucci, G; Mavilia, C; Romagnoli, C; Tanini, A; Vincenzini, MT; Zonefrati, R1
Iantomasi, T; Marcucci, T; Picariello, L; Romagnoli, C; Tonelli, F; Vincenzini, MT1
Berzingi, C; Chen, F; Finkel, MS; Hadfield, JM; Hollander, JM; Miller, DB; Nichols, CE1
Covas, MI; de la Torre, R; Farré, M; Fitó, M; Hernaéz, A; Joglar, J; Kotronoulas, A; Motilva, MJ; Pizarro, N; Robledo, P; Rubió, L; Saez, G; Serra, A; Solà, R; Tormos, C1
Lynch, C; Potter, A; Seefeldt, T; Xie, J; Xie, W1
Dias, IH; Fell, S; Griffiths, HR; Lip, GY; Mistry, J; Polidori, MC; Reis, A; Spickett, CM1
Cui, LB; Li, Q1
Chen, Y; Duan, S; Duan, Y; Han, J; Li, X; Li, Y; Ma, X; Sun, L; Xiang, R; Yang, X; Yao, H1
Li, Y; Liu, J; Ma, X; Ye, BC; Zhang, B; Zuo, P1
Homma, S; Ishida, F; Morita, T; Muramatsu, Y; Sugino, K; Tatebe, J1
Choubey, D; Deepe, GS; Genter, MB; Hsieh, H; Shertzer, HG; Vignesh, KS1
Chen, A; Meng, G; Wang, D; Wei, J; Wu, J; Zhang, Y; Zheng, M1
da Rosa, MS; Leipnitz, G; Ribeiro, RT; Seminotti, B; Wajner, M; Wyse, ATS; Zanatta, Â1
Asanuma, M; Kitamura, Y; Miyazaki, I; Sendo, T; Sumiyoshi, Y; Ushio, S; Wada, Y1
Bernuzzi, F; Bowater, RP; Huynh, TPN; Saha, S; Wormstone, IM1
Guo, J; Han, Q; Hu, L; Huo, H; Li, X; Li, Y; Ma, F; Pan, J; Tang, Z; Wu, H; Zhang, H; Zhao, M1
Delgado-Rizo, V; Fafutis-Morris, M; Godínez-Méndez, LA; Muñoz-Sánchez, G1

Reviews

1 review(s) available for acetylcysteine and glutathione disulfide

ArticleYear
Mechanisms of inhibition of tumor progression.
    Basic life sciences, 1993, Volume: 61

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Benzoates; Benzoic Acid; Butylated Hydroxyanisole; Carcinogens; Carcinoma; Cell Division; Disulfiram; Glutathione; Glutathione Disulfide; Mice; Papilloma; Skin Neoplasms; Vitamin E

1993

Trials

5 trial(s) available for acetylcysteine and glutathione disulfide

ArticleYear
Sodium selenite and N-acetylcysteine in antiretroviral-naive HIV-1-infected patients: a randomized, controlled pilot study.
    European journal of clinical investigation, 1998, Volume: 28, Issue:5

    Topics: Acetylcysteine; Administration, Oral; Adult; Erythrocytes; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; HIV Infections; HIV-1; Humans; Male; Middle Aged; Pilot Projects; Prospective Studies; Reference Values; Selenium; Sodium Selenite; T-Lymphocyte Subsets; Viral Load

1998
Reduction of oxidative stress by oral N-acetyl-L-cysteine treatment decreases plasma soluble vascular cell adhesion molecule-1 concentrations in non-obese, non-dyslipidaemic, normotensive, patients with non-insulin-dependent diabetes.
    Diabetologia, 1998, Volume: 41, Issue:11

    Topics: Acetylcysteine; Administration, Oral; Adult; Blood Glucose; Blood Pressure; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Erythrocytes; Female; Free Radical Scavengers; Glutathione Disulfide; Humans; Insulin; Male; Middle Aged; Oxidative Stress; Reference Values; Triglycerides; Vascular Cell Adhesion Molecule-1

1998
Protective effects of N-acetylcysteine and rutin on the lipid peroxidation of the lung epithelium during the adult respiratory distress syndrome.
    Shock (Augusta, Ga.), 2000, Volume: 13, Issue:1

    Topics: Acetylcysteine; Adult; Aged; APACHE; Breath Tests; Bronchoalveolar Lavage Fluid; Ethane; Female; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Humans; Infusions, Intravenous; Lipid Peroxidation; Lung; Male; Malondialdehyde; Middle Aged; Respiratory Distress Syndrome; Respiratory Mucosa; Rutin; Time Factors

2000
N-acetylcysteine infusion alters blood redox status but not time to fatigue during intense exercise in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:4

    Topics: Acetylcysteine; Acid-Base Equilibrium; Adult; Cross-Over Studies; Cysteine; Cystine; Double-Blind Method; Electrolytes; Exercise; Fatigue; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Humans; Infusions, Intravenous; Male; Osmolar Concentration; Physical Endurance; Potassium; Time Factors

2003
N-acetylcysteine combined with insulin alleviates the oxidative damage of cerebrum via regulating redox homeostasis in type 1 diabetic mellitus canine.
    Life sciences, 2022, Nov-01, Volume: 308

    Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Catalase; Cerebrum; Claudin-1; Diabetes Mellitus, Type 1; Dogs; Glutathione Disulfide; Homeostasis; Hydrogen Peroxide; Insulin; Lipids; Occludin; Oxidation-Reduction; Oxidative Stress; RNA, Messenger

2022

Other Studies

108 other study(ies) available for acetylcysteine and glutathione disulfide

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Regulation of glutathione metabolism in Ehrlich ascites tumour cells.
    The Biochemical journal, 1992, Aug-15, Volume: 286 ( Pt 1)

    Topics: Acetylcysteine; Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cells, Cultured; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Kinetics; Liver; Male; Methionine; Mice; Mice, Inbred Strains; Rats; Reference Values; Subcellular Fractions

1992
Scavenging of hypochlorous acid by lipoic acid.
    Biochemical pharmacology, 1991, Nov-06, Volume: 42, Issue:11

    Topics: Acetylcysteine; alpha 1-Antitrypsin; Enzyme Activation; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hypochlorous Acid; Kinetics; Oxidation-Reduction; Pancreatic Elastase; Thioctic Acid

1991
The generation and subsequent fate of glutathionyl radicals in biological systems.
    The Journal of biological chemistry, 1985, Dec-05, Volume: 260, Issue:28

    Topics: Acetaminophen; Acetylcysteine; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Glutathione Disulfide; Horseradish Peroxidase; Nitrogen; Oxygen; Phenetidine; Spin Labels

1985
Glutathione metabolism and utilization of external thiols by cigarette smoke-challenged, isolated rat and rabbit lungs.
    Toxicology and applied pharmacology, 1988, Volume: 96, Issue:2

    Topics: Acetylcysteine; Animals; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Homeostasis; Lung; Male; Rabbits; Rats; Rats, Inbred Strains; Smoking; Sulfhydryl Compounds

1988
Promotion of cystine uptake and its utilization for glutathione biosynthesis induced by cysteamine and N-acetylcysteine.
    Biochemical pharmacology, 1988, Mar-01, Volume: 37, Issue:5

    Topics: Acetylcysteine; Animals; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cysteamine; Cystine; Female; Glutathione; Glutathione Disulfide; Hydrogen-Ion Concentration; Ovary; Temperature

1988
In vitro effects of N-acetylcysteine on the mutagenicity of direct-acting compounds and procarcinogens.
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: Acetylcysteine; Animals; Biotransformation; Carcinogens; Cysteine; Drug Interactions; Glutathione; Glutathione Disulfide; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Rats; Rats, Inbred Strains; Salmonella typhimurium

1984
Alkylation and peroxidation injury from chemically reactive metabolites.
    Advances in experimental medicine and biology, 1981, Volume: 136 Pt A

    Topics: Acetaminophen; Acetylcysteine; Alkylation; Animals; Antioxidants; Biotransformation; Drug-Related Side Effects and Adverse Reactions; Glutathione; Glutathione Disulfide; Humans; Lipid Peroxides; Liver; Microsomes, Liver; Peroxides; Pharmaceutical Preparations; Vitamin E

1981
N-acetylcysteine failed to improve early microcirculatory alterations of the rat liver after transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 1995, Volume: 8, Issue:4

    Topics: Acetylcysteine; Animals; Cell Adhesion; Female; Glutathione; Glutathione Disulfide; Leukocytes; Liver; Liver Transplantation; Microcirculation; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1995
N-acetylcysteine administration and loaded breathing.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 79, Issue:1

    Topics: Acetylcysteine; Animals; Decerebrate State; Diaphragm; Glutathione; Glutathione Disulfide; Male; Muscle Contraction; Muscle Fatigue; Osmolar Concentration; Rats; Respiration; Respiratory Insufficiency; Work of Breathing

1995
Thiols and the immune system: effect of N-acetylcysteine on T cell system in human subjects.
    Methods in enzymology, 1995, Volume: 251

    Topics: Acetylcysteine; Animals; Cell Line; Cells, Cultured; Culture Techniques; Cysteine; Cytotoxicity, Immunologic; Gene Expression; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Hydrocortisone; Immunotherapy; Leukemia L5178; Lymphocyte Activation; Mercaptoethanol; Mice; Mice, Inbred C3H; Mice, Inbred DBA; NF-kappa B; Receptors, Interleukin-2; Spleen; Sulfhydryl Compounds; T-Lymphocytes; T-Lymphocytes, Cytotoxic

1995
Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine.
    International journal of cancer, 1995, Mar-29, Volume: 61, Issue:1

    Topics: 3T3 Cells; Acetylcysteine; Animals; Carcinoma, Lewis Lung; Cell Movement; Gelatinases; Glutathione; Glutathione Disulfide; Humans; Lung Neoplasms; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Sarcoma, Experimental; Tumor Cells, Cultured

1995
Modulation of transcription factor NF kappa B activity by intracellular glutathione levels and by variations of the extracellular cysteine supply.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1995, Volume: 9, Issue:2

    Topics: Acetylcysteine; Animals; Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; HIV; HIV Infections; Humans; Kinetics; Macaca mulatta; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Sulfhydryl Compounds; T-Lymphocytes; Transcriptional Activation

1995
Antioxidant administration to the mother prevents oxidative stress associated with birth in the neonatal rat.
    Life sciences, 1994, Volume: 54, Issue:26

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Female; Glutathione; Glutathione Disulfide; Liver; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Wistar; Stress, Physiological

1994
Postinsult treatment with N-acetyl-L-cysteine decreases IL-1-induced neutrophil influx and lung leak in rats.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Interleukin-1; Lung; Male; Neutrophils; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Respiration; Respiratory Distress Syndrome

1993
Effects of N-acetylcysteine in the rat heart reperfused after low-flow ischemia: evidence for a direct scavenging of hydroxyl radicals and a nitric oxide-dependent increase in coronary flow.
    Free radical biology & medicine, 1995, Volume: 19, Issue:5

    Topics: Acetylcysteine; Animals; Coronary Circulation; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Heart; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nitric Oxide; Rats; Rats, Sprague-Dawley; Time Factors

1995
Effects of age on levels of cysteine, glutathione and related enzyme activities in livers of mice and rats and an attempt to replenish hepatic glutathione level of mouse with cysteine derivatives.
    Mechanisms of ageing and development, 1996, Sep-30, Volume: 90, Issue:3

    Topics: Acetylcysteine; Aging; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Cystine; Female; Glutathione; Glutathione Disulfide; Liver; Male; Maleates; Mice; Rats; Rats, Inbred F344; Species Specificity

1996
Effect of antioxidants on hyperoxia-induced ICAM-1 expression in human endothelial cells.
    Advances in experimental medicine and biology, 1997, Volume: 411

    Topics: Acetylcysteine; Antioxidants; Biological Transport, Active; Catalase; Cells, Cultured; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Humans; Hyperoxia; Intercellular Adhesion Molecule-1; Lung; Oxidation-Reduction; Pneumonia; Pulmonary Artery; Superoxide Dismutase; Umbilical Veins; Up-Regulation

1997
Distinct mechanisms for N-acetylcysteine inhibition of cytokine-induced E-selectin and VCAM-1 expression.
    The American journal of physiology, 1997, Volume: 273, Issue:2 Pt 2

    Topics: Acetylcysteine; Cell Adhesion; Cell Membrane; Cells, Cultured; Cytokines; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; Genes; Glutathione; Glutathione Disulfide; Humans; Interleukin-1; Monocytes; NF-kappa B; Transcription, Genetic; Vascular Cell Adhesion Molecule-1

1997
Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:6

    Topics: Acetylcysteine; Antioxidants; Bronchoalveolar Lavage Fluid; Female; Glutathione; Glutathione Disulfide; Humans; Immunosuppressive Agents; Lung; Male; Methionine; Middle Aged; Oxidative Stress; Prospective Studies; Pulmonary Fibrosis

1997
Effects of alpha-phenyl N-tert-butylnitrone, a spin trap reagent, on the proliferation of murine hematopoietic progenitor cells in vitro.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 98, Issue:1

    Topics: Acetylcysteine; Animals; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Cyclic N-Oxides; Glutathione; Glutathione Disulfide; Hematopoietic Stem Cells; Interleukin-3; Interleukin-6; Male; Mice; Nitrogen Oxides; Spin Labels; Stem Cell Factor

1997
Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells.
    The Journal of biological chemistry, 1998, Feb-27, Volume: 273, Issue:9

    Topics: Acetylcysteine; Breast Neoplasms; Carcinoma; Cell Death; Drug Resistance, Multiple; Enzyme Activation; Female; Glucose; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Humans; Mitogen-Activated Protein Kinase 1; Oxidative Stress; Signal Transduction; Tumor Cells, Cultured

1998
Toxicity of fotemustine in rat hepatocytes and mechanism-based protection against it.
    Chemico-biological interactions, 1998, Apr-03, Volume: 110, Issue:3

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Cell Survival; Cells, Cultured; Glutathione; Glutathione Disulfide; Kinetics; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Nitrosourea Compounds; Organophosphorus Compounds; Rats; Rats, Wistar; Sulfhydryl Reagents; Vitamin E

1998
Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.
    The Journal of biological chemistry, 1998, Aug-07, Volume: 273, Issue:32

    Topics: Acetylcysteine; Adrenoleukodystrophy; Amitrole; Animals; Antioxidants; Apoptosis; Brain; Cells, Cultured; Ceramides; Cytokines; Diamide; DNA Fragmentation; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Inflammation; Interleukin-1; Multiple Sclerosis; Oxidation-Reduction; Pyrrolidines; Rats; Reactive Oxygen Species; Sphingomyelins; Thiocarbamates; Tumor Necrosis Factor-alpha

1998
Inhibition of tumor necrosis factor-alpha- and interleukin-1-induced endothelial E-selectin expression by thiol-modifying agents.
    Arteriosclerosis, thrombosis, and vascular biology, 1998, Volume: 18, Issue:12

    Topics: Acetylcysteine; Arsenicals; Buthionine Sulfoximine; Cells, Cultured; E-Selectin; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Humans; Interleukin-1; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha

1998
Effects of N-acetylcysteine and 2,3-dimercaptosuccinic acid on lead induced oxidative stress in rat lenses.
    Toxicology, 1998, Sep-15, Volume: 130, Issue:2-3

    Topics: Acetylcysteine; Animals; Chelating Agents; Chromatography, High Pressure Liquid; Cysteine; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Lens, Crystalline; Male; Malondialdehyde; Organometallic Compounds; Oxidative Stress; Rats; Rats, Inbred F344; Succimer

1998
Reduction of endothelial cell related TGFbeta activity by thiols.
    Endothelium : journal of endothelial cell research, 1999, Volume: 6, Issue:3

    Topics: Acetylcysteine; Animals; Cattle; Cells, Cultured; Culture Media, Conditioned; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Oxidation-Reduction; Pulmonary Artery; Sulfhydryl Compounds; Swine; Transforming Growth Factor beta

1999
CD95-Mediated murine hepatic apoptosis requires an intact glutathione status.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:1

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Butylated Hydroxytoluene; Caspase 3; Caspases; Catalase; Cysteine Proteinase Inhibitors; DNA Fragmentation; fas Receptor; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Ketones; Liver; Male; Mice; Mice, Inbred BALB C; Vitamin E

1999
Ethanol ingestion increases activation of matrix metalloproteinases in rat lungs during acute endotoxemia.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:4

    Topics: Acetylcysteine; Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Collagen; Endotoxemia; Endotoxins; Enzyme Activation; Ethanol; Glutathione; Glutathione Disulfide; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Proteins; Rats; Rats, Sprague-Dawley; Salmonella typhimurium

1999
Antioxidant properties of pyruvate mediate its potentiation of beta-adrenergic inotropism in stunned myocardium.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:10

    Topics: Acetylcysteine; Adrenergic beta-Agonists; Animals; Antioxidants; Drug Synergism; Energy Metabolism; Glucose; Glutathione; Glutathione Disulfide; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Pyruvic Acid

1999
Antagonistic effects of pyrrolidine dithiocarbamate and N-acetyl-L-cysteine on surfactant protein A and B mRNAs.
    Experimental lung research, 1999, Volume: 25, Issue:6

    Topics: Acetylcysteine; Blotting, Northern; Carmustine; Cell Line; Clusterin; Drug Synergism; Epithelial Cells; Gene Expression Regulation; Glutathione; Glutathione Disulfide; Glutathione Reductase; Glycoproteins; Humans; Hydrogen Peroxide; Lung; Molecular Chaperones; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Pyrrolidines; Ribonucleases; RNA, Messenger; Thiocarbamates

1999
Regulation of iNOS mRNA levels in endothelial cells by glutathione, a double-edged sword.
    Free radical research, 2000, Volume: 32, Issue:3

    Topics: Acetylcysteine; Carmustine; Cell Line; Cytokines; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Stability; Gene Expression Regulation, Enzymologic; Glutathione; Glutathione Disulfide; Humans; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger

2000
Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells.
    The Journal of biological chemistry, 2000, Jul-14, Volume: 275, Issue:28

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Fetus; Gene Expression Regulation; Glutathione; Glutathione Disulfide; Homeostasis; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Kinetics; NF-kappa B; Nuclear Proteins; Oxidants; Oxidation-Reduction; Pulmonary Alveoli; Pyrrolidines; Rats; Respiratory Mucosa; Thiocarbamates; Transcription Factors

2000
Susceptibility to lipopolysaccharide of cholestatic rat liver produced with bile duct ligation: assessments of the mitochondrial glutathione pool and the effects of N-acetylcysteine.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2000, Volume: 32, Issue:3

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Cholestasis; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Lipopolysaccharides; Liver; Male; Mitochondria, Liver; Neutrophils; Oxidative Stress; Rats

2000
The role of glutathione in DNA damage by potassium bromate in vitro.
    Mutagenesis, 2000, Volume: 15, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Bromates; Carcinogens; Cattle; Cell Line; Chlorates; Chromatography, High Pressure Liquid; Comet Assay; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Epithelial Cells; Free Radicals; Glutathione; Glutathione Disulfide; Humans; Iodates; Kidney; Leukocytes; Potassium Compounds; Rats; Sulfhydryl Compounds; Thymus Gland; Time Factors

2000
Regulation of iNOS expression and glutathione levels in rat liver by oxygen tension.
    FEBS letters, 2000, Jul-07, Volume: 476, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Base Sequence; DNA Primers; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glutathione; Glutathione Disulfide; Hyperoxia; In Vitro Techniques; Liver; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger

2000
Activation of heat shock factor 1 by pyrrolidine dithiocarbamate is mediated by its activities as pro-oxidant and thiol modulator.
    Biochemical and biophysical research communications, 2001, Feb-23, Volume: 281, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Fibroblasts; Glutathione Disulfide; Heat Shock Transcription Factors; Heat-Shock Proteins; Oxidants; Propyl Gallate; Pyrrolidines; Sulfhydryl Compounds; Thiocarbamates; Transcription Factors

2001
Glutathiolation of the proteasome is enhanced by proteolytic inhibitors.
    Archives of biochemistry and biophysics, 2001, May-15, Volume: 389, Issue:2

    Topics: Acetylcysteine; Animals; Base Sequence; Clone Cells; Cysteine; Cysteine Endopeptidases; DNA Primers; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; In Vitro Techniques; Lactones; Liver; Multienzyme Complexes; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Rats; RNA, Messenger; Sulfones

2001
Redox-dependent modulation of lipid synthesis induced by oleic acid in the human intestinal epithelial cell line Caco-2.
    Experimental biology and medicine (Maywood, N.J.), 2001, Volume: 226, Issue:3

    Topics: Acetylcysteine; Aldehydes; Antioxidants; Caco-2 Cells; Copper Sulfate; Glutathione; Glutathione Disulfide; Humans; Intestinal Mucosa; Lipids; Malondialdehyde; Oleic Acids; Oxidants; Oxidation-Reduction

2001
Regulation of LPS induced IL-12 production by IFN-gamma and IL-4 through intracellular glutathione status in human alveolar macrophages.
    Clinical and experimental immunology, 2001, Volume: 124, Issue:2

    Topics: Acetylcysteine; Cell Line; Glutathione; Glutathione Disulfide; Humans; Interferon-gamma; Interleukin-12; Interleukin-4; Lipopolysaccharides; Macrophages, Alveolar; Monocytes; Phenanthrenes

2001
Effects of chronic N-acetylcysteine treatment on the actions of peroxynitrite on aortic vascular reactivity in hypertensive rats.
    Journal of hypertension, 2001, Volume: 19, Issue:7

    Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Drug Synergism; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hypertension; In Vitro Techniques; Isoproterenol; Male; Malondialdehyde; Nitrates; Nitroprusside; Peroxynitrous Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents; Vasomotor System

2001
Thiram-induced cytotoxicity is accompanied by a rapid and drastic oxidation of reduced glutathione with consecutive lipid peroxidation and cell death.
    Toxicology, 2001, Jun-21, Volume: 163, Issue:2-3

    Topics: Acetylcysteine; Adult; Buthionine Sulfoximine; Cell Death; Cell Division; Cell Survival; Cells, Cultured; Female; Fibroblasts; Fungicides, Industrial; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Lipid Peroxidation; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances; Thiram

2001
Induction of mild intracellular redox imbalance inhibits proliferation of CaCo-2 cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:12

    Topics: Acetylcysteine; Buthionine Sulfoximine; Caco-2 Cells; Carmustine; Cell Division; Cell Survival; Cytoplasm; Diamide; Epidermal Growth Factor; Glutathione; Glutathione Disulfide; Humans; Kinetics; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sulfhydryl Reagents

2001
Reduced to oxidized glutathione ratios and oxygen sensing in calf and rabbit carotid body chemoreceptor cells.
    The Journal of physiology, 2001, Nov-15, Volume: 537, Issue:Pt 1

    Topics: Acetylcysteine; Animals; Carotid Body; Catecholamines; Cattle; Chemoreceptor Cells; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hypoxia; Ionomycin; Ionophores; Oxygen; Potassium; Rabbits

2001
The involvement of L-gamma-glutamyl-L-cysteinyl-glycine (glutathione/GSH) in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation of pro-inflammatory cytokine production.
    Biochemical pharmacology, 2002, Jan-15, Volume: 63, Issue:2

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cells, Cultured; Cytokines; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Interleukin-6; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Tumor Necrosis Factor-alpha

2002
Apoptosis in mitotic competent undifferentiated cells is induced by cellular redox imbalance independent of reactive oxygen species production.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:8

    Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Differentiation; Cytochrome c Group; Dehydroepiandrosterone; Diamide; Drug Synergism; Enzyme Activation; Free Radical Scavengers; Glucose; Glutathione; Glutathione Disulfide; Kinetics; Mitosis; NADP; Oxidation-Reduction; PC12 Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species

2002
Lipid peroxide-induced redox imbalance differentially mediates CaCo-2 cell proliferation and growth arrest.
    Cell proliferation, 2002, Volume: 35, Issue:4

    Topics: Acetylcysteine; Biomarkers; Caco-2 Cells; Cell Division; Enterocytes; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Humans; Lipid Peroxidation; Lipid Peroxides; Thymidine; Tritium

2002
Oxidation-reduction (redox) controls fetal hypoplastic lung growth.
    The Journal of surgical research, 2002, Volume: 106, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Congenital Abnormalities; Embryonic and Fetal Development; Fetus; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Lung; Organ Culture Techniques; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

2002
Increases in tumor necrosis factor-alpha in response to thyroid hormone-induced liver oxidative stress in the rat.
    Free radical research, 2002, Volume: 36, Issue:7

    Topics: Acetylcysteine; Animals; Body Temperature; Enzyme-Linked Immunosorbent Assay; Female; Free Radical Scavengers; Gadolinium; Glutathione; Glutathione Disulfide; Liver; Oligonucleotides, Antisense; Organothiophosphorus Compounds; Oxidative Stress; Oxygen Consumption; Phosphorothioate Oligonucleotides; Rats; Rats, Sprague-Dawley; Time Factors; Tocopherols; Triiodothyronine; Tumor Necrosis Factor-alpha

2002
Intracellular redox regulation by a cystine derivative suppresses UV-induced NF-kappa B activation.
    FEBS letters, 2002, Aug-28, Volume: 526, Issue:1-3

    Topics: Acetylcysteine; Antioxidants; Cell Line; Cell Nucleus; Cystine; Cytosol; Glutathione; Glutathione Disulfide; Humans; Kinetics; NF-kappa B; Oxidation-Reduction; Ultraviolet Rays

2002
Effect of alpha-tocopherol and N-acetylcysteine on benzoyl peroxide toxicity in human keratinocytes.
    Journal of biochemical and molecular toxicology, 2004, Volume: 18, Issue:2

    Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antioxidants; Benzoyl Peroxide; Cell Line; Cell Membrane; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Humans; Keratinocytes; Mice

2004
Redox imbalance induced by contact sensitizers triggers the maturation of dendritic cells.
    The Journal of investigative dermatology, 2005, Volume: 124, Issue:3

    Topics: Acetylcysteine; Antigens, CD; B7-2 Antigen; Cells, Cultured; Dendritic Cells; Dermatitis, Contact; Glutathione; Glutathione Disulfide; Humans; Kinetics; MAP Kinase Signaling System; Membrane Glycoproteins; Monocytes; Nickel; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Up-Regulation

2005
Decreased susceptibility of differentiated PC12 cells to oxidative challenge: relationship to cellular redox and expression of apoptotic protease activator factor-1.
    Cell death and differentiation, 2005, Volume: 12, Issue:8

    Topics: Acetylcysteine; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Blotting, Western; Caspases; Diamide; Ethacrynic Acid; Glutathione; Glutathione Disulfide; Mitochondria; Oxidative Stress; PC12 Cells; Proteins; Rats; tert-Butylhydroperoxide

2005
Effects of N-acetylcysteine on lead-exposed PC-12 cells.
    Archives of environmental contamination and toxicology, 2005, Volume: 49, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Glutathione; Glutathione Disulfide; Lead; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; PC12 Cells; Rats; Trypan Blue

2005
Nebulized N-acetyl cysteine protects the pulmonary graft inside the non-heart-beating donor.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005, Volume: 24, Issue:9

    Topics: Acetylcysteine; Aerosols; Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Lung; Lung Transplantation; Organ Preservation; Reperfusion; Sus scrofa; Temperature; Vascular Resistance

2005
Direct measurement of the rate of glutathione synthesis in 1-chloro-2,4-dinitrobenzene treated human erythrocytes.
    Redox report : communications in free radical research, 2006, Volume: 11, Issue:1

    Topics: Acetylcysteine; Buthionine Sulfoximine; Dinitrochlorobenzene; Erythrocytes; Glucose; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Glutathione Synthase; Glutathione Transferase; Hemolysis; Humans; Methemoglobin; Oxidation-Reduction

2006
A novel antioxidant N-acetylcysteine amide prevents gp120- and Tat-induced oxidative stress in brain endothelial cells.
    Experimental neurology, 2006, Volume: 201, Issue:1

    Topics: Acetylcysteine; Animals; Brain; Caspase 3; Caspases; Catalase; Cell Line; Cell Survival; Endothelial Cells; Gene Products, tat; Glutathione; Glutathione Disulfide; Glutathione Reductase; HIV Envelope Protein gp120; Intracellular Fluid; Malondialdehyde; Molecular Structure; Oxidative Stress; Rats; Reactive Oxygen Species

2006
Exposure to 5-bromo-2'-deoxyuridine induces oxidative stress and activator protein-1 DNA binding activity in the embryo.
    Birth defects research. Part A, Clinical and molecular teratology, 2006, Volume: 76, Issue:8

    Topics: Abnormalities, Drug-Induced; Acetylcysteine; Animals; Antioxidants; Bone and Bones; Bromodeoxyuridine; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Gestational Age; Glutathione; Glutathione Disulfide; Liver; Mice; Oxidative Stress; Pregnancy; Protein Binding; Teratogens; Transcription Factor AP-1; Yolk Sac

2006
The activity of aldose reductase is elevated in diabetic mouse heart.
    Journal of pharmacological sciences, 2007, Volume: 103, Issue:4

    Topics: Acetylcysteine; Aldehyde Reductase; Animals; Blotting, Northern; Blotting, Western; Diabetes Mellitus, Experimental; Enzyme Activation; Free Radical Scavengers; Glutathione Disulfide; Male; Mice; Muscle Cells; Myocardium; RNA, Messenger; Streptozocin; Thiobarbituric Acid Reactive Substances

2007
4-Methoxyestradiol-induced oxidative injuries in human lung epithelial cells.
    Toxicology and applied pharmacology, 2007, May-01, Volume: 220, Issue:3

    Topics: Acetylcysteine; Cell Line; Cell Proliferation; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Epithelial Cells; Estradiol; Female; Free Radical Scavengers; Glutathione Disulfide; Humans; Lung; Mitotic Index; Models, Biological; Oxidative Stress; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Spindle Apparatus; Superoxide Dismutase; Tubulin

2007
Manipulation of energy and redox states in the C6 glioma cells by buthionine sulfoxamine and N-acetylcysteine and the effect on cell survival to cadmium toxicity.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, Apr-15, Volume: 53, Issue:1

    Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cadmium; Cell Line, Tumor; Cell Survival; Energy Metabolism; Glutathione; Glutathione Disulfide; Humans; Oxidation-Reduction; Rats

2007
Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.
    Biochemistry, 2007, Jul-03, Volume: 46, Issue:26

    Topics: Acetylcysteine; Amino Acid Sequence; Binding Sites; Buthionine Sulfoximine; Camptothecin; Cell Line, Tumor; Cross-Linking Reagents; Cysteine; Diamide; DNA Damage; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutaral; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Models, Molecular; Oxidative Stress; Phosphorylation; Recombinant Proteins; Tandem Mass Spectrometry; tert-Butylhydroperoxide; Tumor Suppressor Protein p53

2007
Hydrogen sulfide mediates the vasoactivity of garlic.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-13, Volume: 104, Issue:46

    Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Electrochemistry; Erythrocytes; Garlic; Glutathione; Glutathione Disulfide; Humans; Hydrogen Sulfide

2007
The proteasome and intracellular redox status: implications for apoptotic regulation in lens epithelial cells.
    Current eye research, 2007, Volume: 32, Issue:10

    Topics: Acetylcysteine; Animals; Apoptosis; Cells, Cultured; Cysteine Proteinase Inhibitors; Epithelial Cells; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; In Vitro Techniques; Intracellular Membranes; Lens, Crystalline; Leupeptins; Mice; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptide Hydrolases; Proteasome Endopeptidase Complex

2007
Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis.
    Free radical biology & medicine, 2008, Mar-01, Volume: 44, Issue:5

    Topics: Acetylcysteine; Antifibrinolytic Agents; Apoptosis; Biological Transport; Blotting, Western; Caspases; Cell Membrane; Cells, Cultured; Colon; Cytochromes c; Cytosol; Dicumarol; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxygen Consumption; Protein Transport; Vitamin K 3

2008
Effects of hydrogen peroxide treatment on thiol contents in fresh-cut asparagus (Asparagus officinalis) spears.
    International journal of food sciences and nutrition, 2009, Volume: 60, Issue:1

    Topics: Acetylcysteine; Antioxidants; Asparagus Plant; Captopril; Cysteine; Disinfectants; Food Handling; Food Preservatives; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Nutritive Value; Oxidative Stress; Sulfhydryl Compounds

2009
GSH-dependent iNOS and HO-1 mediated apoptosis of human Jurkat cells induced by nickel(II).
    Environmental toxicology, 2009, Volume: 24, Issue:4

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Cells, Cultured; Glutathione; Glutathione Disulfide; Heme Oxygenase-1; Humans; Jurkat Cells; Nickel; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Reactive Oxygen Species; T-Lymphocytes

2009
Effects of mitochondrial poisons on glutathione redox potential and carotid body chemoreceptor activity.
    Respiratory physiology & neurobiology, 2009, Jan-01, Volume: 165, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Carotid Body; Catecholamines; Chemoreceptor Cells; Diaphragm; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione; Glutathione Disulfide; In Vitro Techniques; Male; Mitochondria; Oxidation-Reduction; Poisons; Rats; Rats, Wistar; Reactive Oxygen Species

2009
Effects of glutathione reductase inhibition on cellular thiol redox state and related systems.
    Archives of biochemistry and biophysics, 2009, May-01, Volume: 485, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; Disulfides; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione Disulfide; Glutathione Reductase; Intracellular Space; NAD; NADP; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Thiocarbamates

2009
N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes.
    BMC pharmacology, 2009, Apr-15, Volume: 9

    Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Catalase; Cell Line; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Doxorubicin; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Time Factors

2009
The redox state of glutathione regulates the hypoxic induction of HIF-1.
    European journal of pharmacology, 2009, Mar-15, Volume: 606, Issue:1-3

    Topics: Acetylcysteine; Animals; Azoles; Cell Line, Tumor; Enzyme Inhibitors; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Isoindoles; Organoselenium Compounds; Oxidation-Reduction; RNA, Messenger; Transcriptional Activation; Vascular Endothelial Growth Factor A

2009
Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation.
    Free radical biology & medicine, 2009, Jul-15, Volume: 47, Issue:2

    Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Drug Synergism; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Oxidative Stress; Radiation Tolerance; Sulfhydryl Compounds; Thiocarbamates; X-Rays

2009
L-2-Oxothiazolidine-4-carboxylate reverses glutathione oxidation and delays fatigue of skeletal muscle in vitro.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Diaphragm; Fatigue; Free Radical Scavengers; Glutathione Disulfide; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Oxidation-Reduction; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazolidines

2009
Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line.
    BMC neuroscience, 2009, May-22, Volume: 10

    Topics: Acetylcysteine; Analysis of Variance; Antiviral Agents; Apoptosis; Astrocytoma; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Glutathione; Glutathione Disulfide; HIV-1; Humans; Microscopy, Electron; Oxidative Stress; Telomere; Time Factors

2009
HPLC analysis of human erythrocytic glutathione forms using OPA and N-acetyl-cysteine ethyl ester: evidence for nitrite-induced GSH oxidation to GSSG.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Oct-15, Volume: 877, Issue:28

    Topics: Acetylcysteine; Adult; Chromatography, High Pressure Liquid; Erythrocytes; Female; Glutathione; Glutathione Disulfide; Humans; Male; Nitrites; o-Phthalaldehyde; Oxidation-Reduction; Young Adult

2009
HIV proteins (gp120 and Tat) and methamphetamine in oxidative stress-induced damage in the brain: potential role of the thiol antioxidant N-acetylcysteine amide.
    Free radical biology & medicine, 2010, May-15, Volume: 48, Issue:10

    Topics: Acetylcysteine; AIDS Dementia Complex; Animals; Antioxidants; Blood-Brain Barrier; Brain; Glutathione Disulfide; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Illicit Drugs; Malondialdehyde; Methamphetamine; Mice; Mice, Inbred Strains; Oxidative Stress; Risk Factors; tat Gene Products, Human Immunodeficiency Virus; Tight Junctions

2010
Differential metabolomics for quantitative assessment of oxidative stress with strenuous exercise and nutritional intervention: thiol-specific regulation of cellular metabolism with N-acetyl-L-cysteine pretreatment.
    Analytical chemistry, 2010, Apr-01, Volume: 82, Issue:7

    Topics: Acetylcarnitine; Acetylcysteine; Administration, Oral; Carnitine; Electrophoresis, Capillary; Exercise; Glutathione; Glutathione Disulfide; Humans; Male; Metabolomics; Methylhistidines; Oxidative Stress; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Young Adult

2010
Role of ROS in ischemia-induced lung angiogenesis.
    American journal of physiology. Lung cellular and molecular physiology, 2010, Volume: 299, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Glutathione; Glutathione Disulfide; Ischemia; Lung; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; NF-E2-Related Factor 2; Pulmonary Artery; Reactive Oxygen Species

2010
Comparison of the protective actions of N-acetylcysteine, hypotaurine and taurine against acetaminophen-induced hepatotoxicity in the rat.
    Journal of biomedical science, 2010, Aug-24, Volume: 17 Suppl 1

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Liver; Liver Diseases; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Taurine

2010
The role of intracellular glutathione in the progression of Chlamydia trachomatis infection.
    Free radical biology & medicine, 2010, Dec-15, Volume: 49, Issue:12

    Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Survival; Chlamydia Infections; Chlamydia trachomatis; Glutathione; Glutathione Disulfide; HeLa Cells; Humans; Hydrogen Peroxide; Inclusion Bodies; Proteome

2010
Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: relevance for anti-aging intervention.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:3

    Topics: Acetylcysteine; Adult; Antioxidants; Cells, Cultured; Cellular Senescence; Curcuma; Curcumin; DNA Damage; Enzyme Inhibitors; Female; Fibroblasts; Glutathione Disulfide; Glutathione Transferase; Heme Oxygenase-1; Humans; Oxidation-Reduction; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Skin; Spices

2011
Comparative evaluation of N-acetylcysteine (NAC) and N-acetylcysteine amide (NACA) on glutamate and lead-induced toxicity in CD-1 mice.
    Toxicology letters, 2011, Feb-25, Volume: 201, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Chelating Agents; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Lead; Male; Malondialdehyde; Mice; Phospholipases A2; Reactive Oxygen Species

2011
Protective effect of N-acetyl-L-cysteine against maneb induced oxidative and apoptotic injury in Chinese hamster V79 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:4

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Cricetinae; Cricetulus; Fungicides, Industrial; Glutathione; Glutathione Disulfide; In Situ Nick-End Labeling; Lipid Peroxidation; Maneb; Thiobarbituric Acid Reactive Substances

2011
Antioxidative effects of N-acetylcysteine, lipoic acid, taurine, and curcumin in the muscle of Cyprinus carpio L. exposed to cadmium.
    Arhiv za higijenu rada i toksikologiju, 2011, Volume: 62, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Carps; Catalase; Curcumin; Enzyme Inhibitors; Free Radical Scavengers; Glutathione Disulfide; Glutathione Peroxidase; Lipid Peroxidation; Muscle, Skeletal; Oxidative Stress; Superoxide Dismutase; Taurine; Thioctic Acid

2011
A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium.
    Cellular immunology, 2011, Volume: 270, Issue:1

    Topics: Acetylcysteine; Alveolar Epithelial Cells; Buthionine Sulfoximine; Cells, Cultured; Enzyme Activation; Glutamate-Cysteine Ligase; Glutathione Disulfide; Humans; Imidazoles; Interleukin-1beta; Interleukin-6; MAP Kinase Signaling System; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Alveoli; Pyridines; Tumor Necrosis Factor-alpha

2011
Direct detection of biologically significant thiols and disulfides with manganese(IV) chemiluminescence.
    Analytical chemistry, 2011, Aug-01, Volume: 83, Issue:15

    Topics: Acetylcysteine; Adult; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Cystine; Disulfides; Female; Glutathione; Glutathione Disulfide; Homocysteine; Homocystine; Humans; Luminescent Measurements; Male; Manganese; Oxidative Stress; Sulfhydryl Compounds; Young Adult

2011
Oxidative state and IL-6 production in intestinal myofibroblasts of Crohn's disease patients.
    Inflammatory bowel diseases, 2011, Volume: 17, Issue:8

    Topics: Acetylcysteine; Adult; Buthionine Sulfoximine; Cell Line; Colon; Crohn Disease; Female; Glutathione; Glutathione Disulfide; Humans; Ileum; Interleukin-6; Lipopolysaccharides; Male; Middle Aged; Mitogen-Activated Protein Kinase 3; Myofibroblasts; N-Formylmethionine Leucyl-Phenylalanine; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Tumor Necrosis Factor-alpha

2011
Absence of SOD1 leads to oxidative stress in peripheral nerve and causes a progressive distal motor axonopathy.
    Experimental neurology, 2012, Volume: 233, Issue:1

    Topics: Acetylcysteine; Age Factors; Analysis of Variance; Animals; Axons; Bacterial Proteins; Calcium-Binding Proteins; Chromatography, High Pressure Liquid; DNA-Binding Proteins; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Glutathione; Glutathione Disulfide; Luminescent Proteins; Mice; Mice, Knockout; Microfilament Proteins; Muscle Denervation; Muscle, Skeletal; Nerve Fibers; Neuromuscular Junction; Oxidation-Reduction; Oxidative Stress; Peripheral Nerves; Peripheral Nervous System Diseases; Presynaptic Terminals; Skin; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquitin Thiolesterase; Ubiquitins

2012
Glutathione-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:4

    Topics: Acetylcysteine; Animals; Cytosol; Dinitrochlorobenzene; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Green Fluorescent Proteins; Heart; HEK293 Cells; Homeostasis; Humans; Hydrogen Peroxide; Indicators and Reagents; Mitochondria; Myocardium; Oxidants; Oxidation-Reduction; Oxidative Stress; Protein Subunits; Rats; Reactive Oxygen Species; Thioredoxins

2012
Impaired synthesis contributes to diabetes-induced decrease in liver glutathione.
    International journal of molecular medicine, 2012, Volume: 29, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione; Glutathione Disulfide; Heme Oxygenase-1; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Taurine

2012
Protective role of dietary N-acetylcysteine on the oxidative stress induced by cylindrospermopsin in tilapia (Oreochromis niloticus).
    Environmental toxicology and chemistry, 2012, Volume: 31, Issue:7

    Topics: Acetylcysteine; Alkaloids; Animals; Bacterial Toxins; Cichlids; Cyanobacteria; Cyanobacteria Toxins; Diet; Dietary Supplements; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Transferase; Kidney; Lipid Peroxidation; Liver; Male; Oxidative Stress; Protein Carbonylation; Uracil

2012
Role of GSH/GSSG redox couple in osteogenic activity and osteoclastogenic markers of human osteoblast-like SaOS-2 cells.
    The FEBS journal, 2013, Volume: 280, Issue:3

    Topics: Acetylcysteine; Biomarkers, Tumor; Blotting, Western; Buthionine Sulfoximine; Cell Differentiation; Cell Line, Tumor; Core Binding Factor Alpha 1 Subunit; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Humans; Osteoblasts; Osteoclasts; Osteogenesis; Osteoprotegerin; Oxidation-Reduction; RANK Ligand; Reverse Transcriptase Polymerase Chain Reaction

2013
Role of N-acetylcysteine and GSH redox system on total and active MMP-2 in intestinal myofibroblasts of Crohn's disease patients.
    International journal of colorectal disease, 2013, Volume: 28, Issue:7

    Topics: Acetylcysteine; Adult; Buthionine Sulfoximine; Crohn Disease; Enzyme Activation; Glutathione; Glutathione Disulfide; Humans; Intestines; Intracellular Space; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Middle Aged; Mitogen-Activated Protein Kinases; Myofibroblasts; Oxidation-Reduction; Phosphorylation; Protein Kinase Inhibitors; Tumor Necrosis Factor-alpha; Young Adult

2013
Comparative evaluation of the effects of taurine and thiotaurine on alterations of the cellular redox status and activities of antioxidant and glutathione-related enzymes by acetaminophen in the rat.
    Advances in experimental medicine and biology, 2013, Volume: 776

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Glutathione Reductase; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Taurine

2013
N-acetylcysteine reverses cardiac myocyte dysfunction in a rodent model of behavioral stress.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Aug-15, Volume: 115, Issue:4

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cardiomyopathies; Catalase; Disease Models, Animal; Epinephrine; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Isoproterenol; Male; Myocardium; Myocytes, Cardiac; Norepinephrine; Oxidative Stress; Rats; Rats, Sprague-Dawley

2013
Dose-dependent metabolic disposition of hydroxytyrosol and formation of mercapturates in rats.
    Pharmacological research, 2013, Volume: 77

    Topics: Acetylcysteine; Animals; Antioxidants; Dose-Response Relationship, Drug; Female; Glutathione; Glutathione Disulfide; Male; Phenylethyl Alcohol; Polyphenols; Rats

2013
Evaluation of a dithiocarbamate derivative as a model of thiol oxidative stress in H9c2 rat cardiomyocytes.
    Free radical biology & medicine, 2014, Volume: 70

    Topics: Acetylcysteine; Animals; Cardiovascular Diseases; Cell Line; Glutathione; Glutathione Disulfide; Humans; Myocytes, Cardiac; Oxidative Stress; Rats; Sulfhydryl Compounds; Thiocarbamates

2014
Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation.
    Free radical biology & medicine, 2014, Volume: 75

    Topics: Acetylcysteine; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cell Line, Tumor; Cell Survival; Cholesterol, LDL; Desipramine; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Humans; Hydroxycholesterols; Lipid Metabolism; Lipoproteins, LDL; Membrane Microdomains; Oxidation-Reduction; Sphingomyelin Phosphodiesterase

2014
Combined inhibitory effects of low temperature and N-acetyl-l-cysteine on the postovulatory aging of mouse oocytes.
    Zygote (Cambridge, England), 2016, Volume: 24, Issue:2

    Topics: Acetylcysteine; Animals; Blastocyst; Cells, Cultured; Cellular Senescence; Cold Temperature; Female; Fertilization in Vitro; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Male; Mice; Microscopy, Confocal; Oocytes; Ovulation; Proto-Oncogene Proteins c-bcl-2; Time Factors

2016
Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake.
    The Journal of biological chemistry, 2015, Sep-04, Volume: 290, Issue:36

    Topics: Acetylcysteine; Animals; Antimetabolites; Blotting, Western; Buthionine Sulfoximine; CD36 Antigens; Cell Line; Free Radical Scavengers; Gene Expression; Glutathione; Glutathione Disulfide; Lipoproteins, LDL; Macrophages; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma; Protein Biosynthesis; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2015
Ultrasensitive and selective assay of glutathione species in arsenic trioxide-treated leukemia HL-60 cell line by molecularly imprinted polymer decorated electrochemical sensors.
    Biosensors & bioelectronics, 2016, Jun-15, Volume: 80

    Topics: Acetylcysteine; Arsenic Trioxide; Arsenicals; Biosensing Techniques; Dielectric Spectroscopy; Glutathione; Glutathione Disulfide; HL-60 Cells; Humans; Leukemia; Molecular Imprinting; Oxides; Polymers

2016
Effect of inhaled N-acetylcysteine monotherapy on lung function and redox balance in idiopathic pulmonary fibrosis.
    Respiratory investigation, 2016, Volume: 54, Issue:3

    Topics: Acetylcysteine; Administration, Inhalation; Aged; Disease Progression; Female; Glutathione; Glutathione Disulfide; Humans; Idiopathic Pulmonary Fibrosis; Male; Retrospective Studies; ROC Curve; Vital Capacity

2016
Mechanistic studies of the toxicity of zinc gluconate in the olfactory neuronal cell line Odora.
    Toxicology in vitro : an international journal published in association with BIBRA, 2016, Volume: 35

    Topics: Acetophenones; Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Caspase 1; Caspase Inhibitors; Cell Line; Cell Survival; Gluconates; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Interleukin-1beta; NADPH Oxidases; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; NLR Family, Pyrin Domain-Containing 3 Protein; Olfactory Mucosa; Rats

2016
The Glutaminase-1 Inhibitor 968 Enhances Dihydroartemisinin-Mediated Antitumor Efficacy in Hepatocellular Carcinoma Cells.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Artemisinins; Benzophenanthridines; Cell Line; Cell Line, Tumor; Drug Combinations; Drug Synergism; Endothelial Cells; Enzyme Inhibitors; Gene Expression; Glutaminase; Glutathione; Glutathione Disulfide; Hepatocytes; Humans; Organ Specificity; Reactive Oxygen Species

2016
Disruption of Brain Redox Homeostasis, Microglia Activation and Neuronal Damage Induced by Intracerebroventricular Administration of S-Adenosylmethionine to Developing Rats.
    Molecular neurobiology, 2019, Volume: 56, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Brain; Calcium-Binding Proteins; Glutathione Disulfide; Heme Oxygenase-1; Homeostasis; Injections, Intraventricular; Lipids; Malondialdehyde; Melatonin; Microfilament Proteins; Microglia; Neurons; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species; S-Adenosylmethionine; Synaptophysin; tau Proteins

2019
N-Acetylcysteine Attenuates the Anxiety-Like Behavior and Spatial Cognition Impairment Induced by Doxorubicin and Cyclophosphamide Combination Treatment in Rats.
    Pharmacology, 2021, Volume: 106, Issue:5-6

    Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Cognitive Dysfunction; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Glutathione; Glutathione Disulfide; Hippocampus; Interleukin-6; Male; Oxidative Stress; Rats, Wistar; Spatial Navigation; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2021
GSH Levels Serve As a Biological Redox Switch Regulating Sulforaphane-Induced Cell Fate in Human Lens Cells.
    Investigative ophthalmology & visual science, 2021, 12-01, Volume: 62, Issue:15

    Topics: Acetylcysteine; Activating Transcription Factor 6; Aged; Aged, 80 and over; Anticarcinogenic Agents; Apoptosis; Biomarkers; Cell Line; Cell Survival; Chromatography, Liquid; Epithelial Cells; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Immunoblotting; Isothiocyanates; Lens, Crystalline; Membrane Potential, Mitochondrial; Middle Aged; Oxidation-Reduction; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Sulfoxides; Tandem Mass Spectrometry

2021
Effect of Antioxidant Supplementation on NET Formation Induced by LPS In Vitro; the Roles of Vitamins E and C, Glutathione, and N-acetyl Cysteine.
    International journal of molecular sciences, 2023, Aug-24, Volume: 24, Issue:17

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Dietary Supplements; Glutathione; Glutathione Disulfide; Horses; Lipopolysaccharides; Reactive Oxygen Species; Vitamin E; Vitamins

2023