acetylcysteine has been researched along with gemcitabine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Beijnen, JH; Brouwers, EE; Huitema, AD; Schellens, JH | 1 |
| Costanzo, C; Dalla Pozza, E; Dando, I; Donadelli, M; Fiorini, C; Menegazzi, M; Palmieri, M; Sgarbossa, A | 1 |
| Daneker, GW; Kim, B; McDonald, JF; Mezencev, R; Sulchek, TA; Wang, L; Xu, W | 1 |
| Distler, AM; Hill, EG; Lemasters, JJ; Manevich, Y; Mieyal, JJ; Nieminen, AL; Qanungo, S; Shaner, B; Townsend, DM; Uys, JD | 1 |
| Hu, Q; Ji, S; Liu, J; Liu, W; Ni, Q; Qin, Y; Sun, Q; Xiang, J; Xu, J; Xu, W; Yu, X; Zhang, B; Zhang, Z | 1 |
| Bajpai, P; Pandey, P; Pathak, N; Sayyed, U; Siddiqui, MH; Tiwari, RK | 1 |
| Amin, S; K Pandey, M; Karelia, DN; Kim, S; Lu, J; Plano, D; Sharma, AK | 1 |
1 review(s) available for acetylcysteine and gemcitabine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
10 other study(ies) available for acetylcysteine and gemcitabine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
The effects of sulfur-containing compounds and gemcitabine on the binding of cisplatin to plasma proteins and DNA determined by inductively coupled plasma mass spectrometry and high performance liquid chromatography-inductively coupled plasma mass spectro
Topics: Acetylcysteine; Antineoplastic Agents; Blood Proteins; Chromatography, High Pressure Liquid; Cisplatin; Deoxycytidine; DNA; Gemcitabine; Glutathione; Humans; Mass Spectrometry; Protein Binding; Thiosulfates | 2008 |
Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine.
Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Ion Channels; Iridoids; Mitochondrial Proteins; Neoplasms; Poly(ADP-ribose) Polymerases; RNA, Messenger; Superoxide Dismutase; Superoxides; Uncoupling Agents; Uncoupling Protein 2 | 2012 |
Molecular analysis of the inhibitory effect of N-acetyl-L-cysteine on the proliferation and invasiveness of pancreatic cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; G1 Phase Cell Cycle Checkpoints; Gemcitabine; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Mitomycin; Pancreatic Neoplasms; Reactive Oxygen Species | 2013 |
N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NFκB pathway.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line, Tumor; Cysteine; Deoxycytidine; Gemcitabine; Glutathione; Humans; Male; Mice; Mice, Nude; NF-kappa B; Oxidative Stress; Pancreatic Neoplasms; Signal Transduction; X-Linked Inhibitor of Apoptosis Protein | 2014 |
dCK negatively regulates the NRF2/ARE axis and ROS production in pancreatic cancer.
Topics: Acetylcysteine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Gemcitabine; Glutamate-Cysteine Ligase; Glutathione; Humans; Kelch-Like ECH-Associated Protein 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-E2-Related Factor 2; Pancreatic Neoplasms; Plasmids; Reactive Oxygen Species; Up-Regulation | 2018 |
Hesperidin Induces ROS-Mediated Apoptosis along with Cell Cycle Arrest at G2/M Phase in Human Gall Bladder Carcinoma.
Topics: Acetylcysteine; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Proliferation; Deoxycytidine; Dose-Response Relationship, Drug; Gallbladder Neoplasms; Gemcitabine; Hesperidin; Humans; Macrophages; Membrane Potential, Mitochondrial; Mice; Reactive Oxygen Species; Tumor Cells, Cultured | 2019 |
Novel Seleno-Aspirinyl Compound AS-10 Induces Apoptosis, G1 Arrest of Pancreatic Ductal Adenocarcinoma Cells, Inhibits Their NF-κB Signaling, and Synergizes with Gemcitabine Cytotoxicity.
Topics: Acetylcysteine; Adenocarcinoma; Apoptosis; Aspirin; Carcinoma, Pancreatic Ductal; Caspases; Cell Line, Tumor; Cell Proliferation; Cytokines; Deoxycytidine; Enzyme Activation; G1 Phase Cell Cycle Checkpoints; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Inflammation Mediators; NF-kappa B; Pancreatic Neoplasms; Signal Transduction; Transcriptome | 2021 |