acetylcysteine and flupirtine

acetylcysteine has been researched along with flupirtine in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (40.00)	29.6817
2010's	3 (60.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Bednarski, PJ; Borlak, J; Keiser, M; Methling, K; Modess, C; Nassif, A; Rosskopf, D; Scheuch, E; Siegmund, W; Terhaag, B	1
Bednarski, PJ; Methling, K; Oswald, S; Scheuch, E; Siegmund, W	1
Berg, T; Borlak, J; van Bömmel, F	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1

Trials

1 trial(s) available for acetylcysteine and flupirtine

Article	Year
Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1. British journal of clinical pharmacology, 2015, Volume: 79, Issue:3 Topics: Acetylcysteine; Activation, Metabolic; Administration, Oral; Adult; Aminopyridines; Analgesics; Animals; Arylamine N-Acetyltransferase; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glucuronosyltransferase; Glutathione S-Transferase pi; Healthy Volunteers; Humans; Injections, Intravenous; Madin Darby Canine Kidney Cells; Male; Multidrug Resistance-Associated Protein 2; Pain Threshold; Polymorphism, Genetic; Young Adult	2015

Article

Year

Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.

British journal of clinical pharmacology, 2015, Volume: 79, Issue:3

Topics: Acetylcysteine; Activation, Metabolic; Administration, Oral; Adult; Aminopyridines; Analgesics; Animals; Arylamine N-Acetyltransferase; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glucuronosyltransferase; Glutathione S-Transferase pi; Healthy Volunteers; Humans; Injections, Intravenous; Madin Darby Canine Kidney Cells; Male; Multidrug Resistance-Associated Protein 2; Pain Threshold; Polymorphism, Genetic; Young Adult

2015

Other Studies

4 other study(ies) available for acetylcysteine and flupirtine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative LC-MS/MS determination of flupirtine, its N-acetylated and two mercapturic acid derivatives in man. Journal of pharmaceutical and biomedical analysis, 2015, Volume: 102 Topics: Acetylation; Acetylcysteine; Aminopyridines; Chromatography, Liquid; Humans; Male; Mass Spectrometry; Tandem Mass Spectrometry	2015
N-acetylcysteine and prednisolone treatment improved serum biochemistries in suspected flupirtine cases of severe idiosyncratic liver injury. Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:2 Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Antidotes; Biomarkers; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Progression; Drug Therapy, Combination; Female; Glucocorticoids; Glutathione; Hepatocytes; Humans; Infusions, Intravenous; Liver; Liver Transplantation; Male; Middle Aged; Prednisolone; Recovery of Function; Retrospective Studies; Severity of Illness Index; Treatment Outcome	2018
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007