acetylcysteine has been researched along with etoposide in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 16 (48.48) | 29.6817 |
| 2010's | 13 (39.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bae, SY; Hong, JY; Jung, C; Kang, SS; Lee, SK; Park, HJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Einhorn, LH; Langefeld, C; Loehrer, PJ; Munshi, NC; Neuman, A; Nichols, CR; Roth, BJ; Sledge, G; Walsh, WB; Williams, SD | 1 |
| Bessho, R; Hirota, H; Kawai, M; Kubota, M; Kuwakado, K; Lin, YW; Matsubara, K; Nishikomori, R; Okuda, A; Wakazono, Y | 1 |
| Fukuchi, K; Gomi, K; Nakamaki, T; Tomoyasu, S; Tsuruoka, N | 1 |
| Athias, A; Bessede, G; Gambert, P; Gueldry, S; Lemaire, S; Lizard, G; Miguet, C; Monier, S; Solary, E; Sordet, O | 1 |
| Dallaporta, B; Daugas, E; Kroemer, G; Loeffler, M; Maisse, C; Pablo, M; Zamzami, N | 1 |
| Lei, S; Ogiso, Y; Omura, S; Tomida, A; Tsuruo, T | 1 |
| Harani, N; Haslett, C; MacKinnon, AC; Rahman, I; Rintoul, R; Sethi, T; Waters, C | 1 |
| Levine, R; Morrow, J; Sentürker, S; Shacter, E; Tschirret-Guth, R | 1 |
| Hayashi, Y; Kawai, N; Kohri, K; Okamoto, T; Sasaki, S; Tozawa, K | 1 |
| Fukuda, T; Kurosu, T; Miki, T; Miura, O | 1 |
| Cotter, TG; England, K; O'Driscoll, C | 1 |
| Aiuchi, T; Hori, K; Horie, M; Kajimoto, S; Masuda, Y; Nakajo, S; Nakaya, K; Shibayama-Imazu, T; Shima, G | 1 |
| Kulms, D; Pöppelmann, B; Schwarz, T; Strozyk, E | 1 |
| Darzynkiewicz, Z; Halicka, HD; Seiter, K; Tanaka, T; Traganos, F | 1 |
| Cai, Y; Ding, J; Lin, L; Lu, J; Miao, Z | 1 |
| Hsu, PC; Hung, HC; Liao, YF; Liu, CC; Liu, GY; Tsay, GJ | 1 |
| Hutchison, CJ; Lattanzi, G; Muter, J; Richards, SA; Ritchie, P | 1 |
| Attia, SM | 1 |
| Bar-Yishay, I; Ben-Yehoyada, M; Burdelova, EO; Fishman, S; Halpern, Z; Mouler Rechtman, M; Shlomai, A | 1 |
| Amamoto, T; Aramaki, H; Koyachi, K; Matsumoto, K; Nishimura, H; Okamoto, Y; Shindo, M; Takeda, S; Yoshida, K | 1 |
| Chaika, ZV; Durnev, AD; Kulakova, AV; Pligina, KL; Zhanataev, AK | 1 |
| Colla, R; De Ciucis, C; Domenicotti, C; Fenoglio, D; Furfaro, AL; Izzotti, A; Marengo, B; Passalacqua, M; Pronzato, MA; Pulliero, A; Ravera, S; Ricciarelli, R; Speciale, A; Traverso, N | 1 |
| Blokland, KEC; Burgess, JK; Grainge, C; Hogaboam, CM; Jaffar, J; Khalil, N; Knight, DA; Mutsaers, SE; Pechkovsky, DV; Prêle, CM; Read, J; Reid, AT; Schuliga, M; Waters, DW; Westall, G | 1 |
| Berkova, N; Cauty, C; Deplanche, M; Diot, A; Dutertre, S; Ezan, F; Götz, F; Langouet, S; Laurent, F; Le Loir, Y; Legembre, P; Mouhali, N; Nguyen, MT; Otto, M; Raulin, L; Taieb, F | 1 |
1 review(s) available for acetylcysteine and etoposide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
32 other study(ies) available for acetylcysteine and etoposide
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; CDC2 Protein Kinase; Checkpoint Kinase 1; Checkpoint Kinase 2; Colonic Neoplasms; Dioxins; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Mice; Mice, Nude; Molecular Structure; Phytolacca americana; Protein Kinases; Seeds; Signal Transduction; Tumor Suppressor Protein p53 | 2015 |
Comparison of N-acetylcysteine and mesna as uroprotectors with ifosfamide combination chemotherapy in refractory germ cell tumors.
Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dysgerminoma; Etoposide; Hematuria; Humans; Ifosfamide; Male; Mesna; Severity of Illness Index; Vinblastine | 1992 |
Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes.
Topics: Acetylcysteine; Apoptosis; Base Sequence; Cytarabine; Endonucleases; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phenanthrolines; Pyrrolidines; T-Lymphocytes; Thiocarbamates; Thymus Gland; Tumor Cells, Cultured | 1994 |
DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells.
Topics: Acetylcysteine; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Cytarabine; Deferoxamine; DNA Damage; Etoposide; Gene Expression Regulation; Hydroxyurea; Polyribosomes; RNA, Messenger; Tumor Cells, Cultured; Ubiquitins | 1998 |
Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Caspases; Cycloheximide; Cytochrome c Group; DNA Fragmentation; Enzyme Activation; Enzyme Precursors; Etoposide; Fatty Acids, Unsaturated; Free Radicals; Glutathione; Humans; Ketocholesterols; Oxidation-Reduction; Reactive Oxygen Species; U937 Cells | 1998 |
Proteasome activation as a critical event of thymocyte apoptosis.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Caspase Inhibitors; Caspases; Catalase; Cells, Cultured; Cysteine Endopeptidases; Dactinomycin; Dexamethasone; Enzyme Activation; Etoposide; fas Receptor; Female; Mice; Mice, Inbred BALB C; Mitochondria; Multienzyme Complexes; Proteasome Endopeptidase Complex; T-Lymphocytes | 2000 |
Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs.
Topics: Acetylcysteine; Animals; Antigens, Neoplasm; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Northern; Cell Cycle; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Glucose; Humans; Hypoxia; Immunoblotting; Isoenzymes; Methotrexate; Mice; Mice, Nude; Multienzyme Complexes; Neoplasm Transplantation; Nucleic Acid Synthesis Inhibitors; Proteasome Endopeptidase Complex; Time Factors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Vincristine | 2000 |
[Arg(6), D-Trp(7,9), N(me)Phe(8)]-substance P (6-11) (antagonist G) induces AP-1 transcription and sensitizes cells to chemotherapy.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Small Cell; Cell Division; CHO Cells; Cricetinae; Drug Synergism; Etoposide; Free Radical Scavengers; Glutathione; Growth Inhibitors; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Lung Neoplasms; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Oligopeptides; Oxidation-Reduction; Reactive Oxygen Species; Stimulation, Chemical; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Induction of apoptosis by chemotherapeutic drugs without generation of reactive oxygen species.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Burkitt Lymphoma; Cisplatin; Cyclic N-Oxides; Etoposide; F2-Isoprostanes; Humans; Hydrogen Peroxide; Metalloporphyrins; Methionine; Oxidants; Reactive Oxygen Species; Spin Labels | 2002 |
N-acetyl-L-cysteine enhances chemotherapeutic effect on prostate cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents; Cisplatin; Etoposide; Humans; Interleukin-6; Male; NF-kappa B; Prostatic Neoplasms; Tumor Cells, Cultured | 2002 |
BCL6 overexpression prevents increase in reactive oxygen species and inhibits apoptosis induced by chemotherapeutic reagents in B-cell lymphoma cells.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Doxycycline; Etoposide; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Humans; Leupeptins; Lymphoma, B-Cell; Membrane Potentials; Mitochondria; Multienzyme Complexes; Mutation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-6; Reactive Oxygen Species; Transcription Factors; Tumor Cells, Cultured | 2003 |
Carbonylation of glycolytic proteins is a key response to drug-induced oxidative stress and apoptosis.
Topics: Acetylcysteine; Apoptosis; Blotting, Western; Carbon; Electrophoresis, Gel, Two-Dimensional; Etoposide; Flow Cytometry; Free Radical Scavengers; Glycolysis; HL-60 Cells; Humans; Hydrazines; Hydrogen Peroxide; Oxidation-Reduction; Oxidative Stress; Precipitin Tests; Proteins; Reactive Oxygen Species; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2004 |
Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Cell Death; Cell Line; Cell Line, Tumor; Coloring Agents; Cytochromes c; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Gene Expression Regulation; Genetic Vectors; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Mitochondria; Naphthoquinones; Oligonucleotide Array Sequence Analysis; Plasmids; Reactive Oxygen Species; RNA, Small Interfering; Subcellular Fractions; Time Factors; Transfection | 2004 |
Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: the type of DNA damage determines the final outcome.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Chromosome Breakage; Cisplatin; Comet Assay; DNA Damage; Doxorubicin; Etoposide; Gamma Rays; Gene Expression Regulation; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1; Interleukin-6; KB Cells; Leupeptins; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; Proteasome Inhibitors; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Sulfones; Transcription, Genetic; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2006 |
Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase.
Topics: Acetylcysteine; Anthraquinones; Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line; DNA Damage; DNA Replication; DNA-Binding Proteins; Etoposide; Flow Cytometry; Free Radical Scavengers; G1 Phase; Histones; Humans; Immunohistochemistry; Mitoxantrone; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Tumor Suppressor Proteins | 2007 |
Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells.
Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA Breaks, Double-Stranded; Drug Resistance, Multiple; Etoposide; Glutathione; Humans; Hydrogen Peroxide; K562 Cells; Naphthoquinones; Reactive Oxygen Species | 2007 |
Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cisplatin; Etoposide; Glutathione; HL-60 Cells; Humans; Leukemia; Membrane Potential, Mitochondrial; Ornithine Decarboxylase; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Putrescine; Reactive Oxygen Species | 2008 |
The accumulation of un-repairable DNA damage in laminopathy progeria fibroblasts is caused by ROS generation and is prevented by treatment with N-acetyl cysteine.
Topics: Acetylcysteine; Age Factors; Aged, 80 and over; Antineoplastic Agents; Child; Contracture; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Etoposide; Fibroblasts; Humans; Hydrogen Peroxide; Male; Oxidants; Progeria; Reactive Oxygen Species; Skin Abnormalities | 2011 |
Dominant lethal mutations of topoisomerase II inhibitors etoposide and merbarone in male mice: a mechanistic study.
Topics: Acetylcysteine; Animals; Dose-Response Relationship, Drug; Etoposide; Female; Fluoresceins; Male; Mice; Mutagenicity Tests; Mutagens; Mutation; Oxidative Stress; Reactive Oxygen Species; Spermatids; Thiobarbiturates; Topoisomerase II Inhibitors | 2012 |
The metabolic regulator PGC-1α links anti-cancer cytotoxic chemotherapy to reactivation of hepatitis B virus.
Topics: Acetylcysteine; Antineoplastic Agents; Bleomycin; Cell Line, Tumor; Cyclophosphamide; Dexamethasone; DNA Damage; Etoposide; Gene Expression Regulation, Viral; Heat-Shock Proteins; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mitochondria; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Transcription Factors; Transcriptional Activation; Up-Regulation; Virus Activation | 2013 |
(-)-Xanthatin induces the prolonged expression of c-Fos through an N-acetyl-L-cysteine (NAC)-sensitive mechanism in human breast cancer MDA-MB-231 cells.
Topics: Acetylcysteine; Antigens, Neoplasm; Antineoplastic Agents; Breast Neoplasms; Cell Division; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Female; Free Radical Scavengers; Furans; GADD45 Proteins; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Intracellular Signaling Peptides and Proteins; Proto-Oncogene Proteins c-fos; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Up-Regulation | 2013 |
[Influence of Acetylcysteine on Cytogenetic Effects of Etoposide in Mouse Oocytes].
Topics: Acetylcysteine; Animals; Chromosome Aberrations; Etoposide; Female; Mice; Mutagenesis; Mutagens; Oocytes | 2016 |
Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Buthionine Sulfoximine; Catalase; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Glutathione; Humans; Hydrogen Peroxide; Lipid Peroxidation; Neuroblastoma; Topoisomerase II Inhibitors; Up-Regulation | 2016 |
Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.
Topics: Acetylcysteine; Biomarkers; Cellular Senescence; Cyclic N-Oxides; Down-Regulation; Etoposide; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Lung; Mitochondria; Myofibroblasts; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rotenone; Sirolimus | 2018 |
Staphylococcus aureus induces DNA damage in host cell.
Topics: Acetylcysteine; Arthritis, Infectious; Bacterial Toxins; Cell Line, Tumor; DNA Damage; DNA Repair; Etoposide; G2 Phase Cell Cycle Checkpoints; Genomic Islands; Guanine; HeLa Cells; Histones; Host-Pathogen Interactions; Humans; Lipoproteins; Osteitis; Osteoblasts; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Reactive Oxygen Species; Staphylococcal Infections; Staphylococcus aureus | 2019 |