acetylcysteine has been researched along with ethacrynic acid in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Epstein, DL; Epstein, MP; Schroeder, A; Tingey, DP | 1 |
| Bonazzi, D; Cavrini, V; Di Pietra, AM; Gatti, R | 1 |
| Fitzgerald, TJ; Klaassen, CD | 1 |
| Bowie, A; Brennan, P; O'Neill, LA | 1 |
| Borsellino, N; D'Alessandro, N; Flugy, A | 1 |
| Hamilton, JW; Maccubbin, AE; Warren, AJ | 1 |
| Ergün, Y; Ogülener, N | 1 |
| Aizawa, S; Asano, J; Hayakari, M; Kudo, T; Ookawa, K; Tsuchida, S | 1 |
| Aw, TY; Ekshyyan, O | 1 |
| Jing, Y; Li, C; Song, D; Wang, R; Zhao, G; Zhao, L | 1 |
| Cisowski, J; Dulak, J; Jozkowicz, A; Kotlinowski, J; Mleczko, K; Taha, H; Was, H; Weigel, G | 1 |
| Bhatia-Kissová, I; Camougrand, N; Deffieu, M; Galinier, A; Manon, S; Salin, B | 1 |
| Araki, W; Oda, A; Tamaoka, A | 1 |
| Carson, DA; Endo, T; Kipps, TJ; Liu, JX; Lu, D; Schmidt-Wolf, IG; Willert, K; Yao, S; Zhou, H | 1 |
| Hasegawa, M; Iguchi, Y; Ishigaki, S; Katsuno, M; Niwa, J; Sobue, G; Takagi, S; Tanaka, F | 1 |
| Brown, SE; Clark, CW; Conlin, SM; Rastogi, A; Timme-Laragy, AR | 1 |
1 review(s) available for acetylcysteine and ethacrynic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
19 other study(ies) available for acetylcysteine and ethacrynic acid
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of topical ethacrynic acid adducts on intraocular pressure in rabbits and monkeys.
Topics: Acetylcysteine; Animals; Corneal Edema; Dose-Response Relationship, Drug; Drug Combinations; Ethacrynic Acid; Intraocular Pressure; Macaca fascicularis; Ophthalmic Solutions; Premedication; Rabbits | 1992 |
Determination of ethacrynic acid in pharmaceutical formulations by difference ultraviolet spectrophotometry after derivatisation with N-acetylcysteine.
Topics: Acetylcysteine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Ethacrynic Acid; Indicators and Reagents; Spectrophotometry, Ultraviolet | 1989 |
Metabolism and biliary excretion of ethacrynic acid.
Topics: Acetylcysteine; Animals; Bile; Carbon Radioisotopes; Chromatography, Thin Layer; Dogs; Ethacrynic Acid; Glutathione; Injections, Intravenous; Male; Rats; Sulfur Radioisotopes; Time Factors | 1974 |
The effects of thiol modifiers on the activation of NF kappa B by interleukin-1.
Topics: Acetylcysteine; Animals; Cell Line; Cell Nucleus; Diamide; Dinitrochlorobenzene; Ethacrynic Acid; Humans; Hydrogen Peroxide; Interleukin-1; Mice; NF-kappa B; Sulfhydryl Reagents; T-Lymphocytes; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured | 1993 |
TNF-induced apoptosis in multidrug resistant friend erythroleukemia is not influenced by the P-glycoprotein and glutathione status of the cell line.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Differentiation; Diuretics; Doxorubicin; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Ethacrynic Acid; Friend murine leukemia virus; Glutathione; Interferon-gamma; Leukemia, Erythroblastic, Acute; Mice; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Detection of mitomycin C-DNA adducts in vivo by 32P-postlabeling: time course for formation and removal of adducts and biochemical modulation.
Topics: Acetylcysteine; Animals; Biotransformation; Buthionine Sulfoximine; Chick Embryo; Cross-Linking Reagents; Dexamethasone; DNA; DNA Adducts; DNA Damage; DNA Repair; Enzyme Induction; Ethacrynic Acid; Glutathione; Glutethimide; Inactivation, Metabolic; Kidney; Liver; Lung; Mitomycin; Phosphorus Radioisotopes; Polychlorinated Biphenyls; Time Factors | 1998 |
A putative role for S-nitrosoglutathione as the source of nitric oxide in photorelaxation of the mouse gastric fundus.
Topics: Acetylcysteine; Animals; Cysteine; Diamide; Enzyme Inhibitors; Ethacrynic Acid; Female; Gastric Fundus; Glutathione; In Vitro Techniques; Isoproterenol; Male; Mice; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; S-Nitrosoglutathione; S-Nitrosothiols; Ultraviolet Rays | 2002 |
Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD-1 and suppression by N-acetyl-L-cysteine.
Topics: Acetylcysteine; Antioxidants; Cell Death; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Ethacrynic Acid; Fluorescence; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Mitogen-Activated Protein Kinases | 2003 |
Decreased susceptibility of differentiated PC12 cells to oxidative challenge: relationship to cellular redox and expression of apoptotic protease activator factor-1.
Topics: Acetylcysteine; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Blotting, Western; Caspases; Diamide; Ethacrynic Acid; Glutathione; Glutathione Disulfide; Mitochondria; Oxidative Stress; PC12 Cells; Proteins; Rats; tert-Butylhydroperoxide | 2005 |
Ethacrynic acid butyl-ester induces apoptosis in leukemia cells through a hydrogen peroxide mediated pathway independent of glutathione S-transferase P1-1 inhibition.
Topics: Acetylcysteine; Apoptosis; Caspases; Catalase; Cell Growth Processes; Ethacrynic Acid; Glutathione S-Transferase pi; HL-60 Cells; Humans; Hydrogen Peroxide; K562 Cells; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute | 2007 |
15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress.
Topics: Acetylcysteine; Cells, Cultured; Colforsin; Cyclic AMP; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Ethacrynic Acid; Ethylmaleimide; Gene Expression; Hemin; Humans; Hydantoins; Interleukin-8; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Protein Kinase Inhibitors; Reactive Oxygen Species; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Superoxide Dismutase; Transfection; Xanthones | 2008 |
Glutathione participates in the regulation of mitophagy in yeast.
Topics: Acetylcysteine; Autophagy; Culture Media; Ethacrynic Acid; Glutathione; Green Fluorescent Proteins; Heat-Shock Proteins; Intracellular Space; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Nitrogen; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Vacuoles | 2009 |
Oxidative stress up-regulates presenilin 1 in lipid rafts in neuronal cells.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Antioxidants; Brain; Cell Line, Tumor; Ethacrynic Acid; Glutathione; Heme Oxygenase-1; Humans; Membrane Microdomains; Mutation; Neurons; Oxidative Stress; Presenilin-1; RNA, Messenger; Up-Regulation | 2010 |
Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway.
Topics: Acetylcysteine; beta Catenin; Cell Line, Tumor; Cell Survival; Cyclin D1; Drug Screening Assays, Antitumor; Ethacrynic Acid; Fibronectins; Frizzled Receptors; Gene Expression Regulation, Leukemic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoid Enhancer-Binding Factor 1; Protein Binding; Receptors, G-Protein-Coupled; Signal Transduction; Wnt Proteins | 2009 |
Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies.
Topics: Acetylcysteine; Animals; Benzamides; Cells, Cultured; Cerebral Cortex; Cinnamates; DNA-Binding Proteins; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Ethacrynic Acid; Glutathione; Green Fluorescent Proteins; Humans; Hydrogen Peroxide; Imidazoles; Indoles; Mice; Mice, Inbred C57BL; Neurons; Oxidants; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Serine; Time Factors; Transfection | 2012 |
Mapping glutathione utilization in the developing zebrafish (Danio rerio) embryo.
Topics: Acetylcysteine; Alkanesulfonic Acids; Animals; Brain; Diethylhexyl Phthalate; Embryo, Nonmammalian; Ethacrynic Acid; Fluorescent Dyes; Fluorocarbons; Glutathione; Glutathione Transferase; Heart; Organogenesis; Pyrazoles; Staining and Labeling; tert-Butylhydroperoxide; Toxicity Tests, Chronic; Zebrafish | 2019 |