acetylcysteine has been researched along with edetic acid in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (31.71) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 7 (17.07) | 29.6817 |
| 2010's | 15 (36.59) | 24.3611 |
| 2020's | 2 (4.88) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Abouelhassan, Y; Bai, F; Burch, GM; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Luesch, H; Nguyen, MT; Norwood, VM; Rolfe, M | 1 |
| Abouelhassan, Y; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Kim, YS; Luesch, H; Tan, H | 1 |
| Gerhardt, W; Gruber, W; Waldenström, J | 1 |
| Ellison, A; Poirier, R | 1 |
| Sandifort, CR | 1 |
| Gruber, W | 1 |
| Corbella, J; Domingo, JL; Llobet, JM | 2 |
| Kägi, JH; Pande, J; Vasák, M | 1 |
| Lieberman, J | 1 |
| Sugar, A; Waltman, SR | 1 |
| Bateman, DN; Rawlins, MD; Woodhouse, KW | 1 |
| Henderson, AR; Nealon, DA; Pettit, SM | 1 |
| Dubowitz, V; Heckmatt, J; Moss, DW; Parmar, C; Sewry, C; Whitaker, KB; Wikowski, J | 1 |
| Itoh, M; Joh, T; Seno, K; Yokoyama, Y | 1 |
| Aabech, J; Andersen, JT | 1 |
| Hinze, H; Lenz, AG; Maier, KL; Meyer, B | 1 |
| Altindag, ZZ; Fuchs, D; Wachter, H; Wede, I; Widner, B | 1 |
| Lin, MC; Ou, CC; Tsao, SM; Yin, MC | 1 |
| Andrew, SE; Blalock, TD; Brooks, DE; Gelatt, KN; Kallberg, ME; Komaromy, AM; Lassaline, ME; Ollivier, FJ; Schultz, GS; Stevens, GR; van Setten, GB | 1 |
| Hazell, AS; Kennedy, G; Norenberg, MD; Normandin, L; Yi, JH | 1 |
| Kuo, YM; Wu, Z; Yang, Y; Zhou, B | 1 |
| Doroshow, JH | 1 |
| Bartosz, G; Coulon, J; Dossot, M; Leroy, P; Marchand, S; Matoub, L | 1 |
| Abraham, L; Ates, B; Ercal, N | 1 |
| Beach, DG; Gabryelski, W; Manderville, RA; Witham, AA | 1 |
| Caleo, M; Cecchini, M; Signore, G; Tonazzini, I; Voccoli, V | 1 |
| Borlee, BR; Borlee, GI; Ferris, RA; Hennet, ML; Loncar, KD; McCue, PM | 1 |
| Kimmitt, BA; Moore, GE; Stiles, J | 1 |
| Fujimoto, K; Fujita, M; Horie, N; Kasahara, T; Katsuoka, Y; Kawakami, T; Kojima, H; Kojima, K; Kurokawa, Y; Kusakari, K; Ono, A; Sugawara, T; Tahara, Y; Tanabe, H; Wakabayashi, K; Watanabe, S; Yamamoto, Y; Yokoyama, H | 1 |
| Chan, WY; Hickey, EE; Hill, PB; Khazandi, M; Page, SW; Trott, DJ | 1 |
| Dear, J | 1 |
| Ignarro, LJ; Jynge, P; Karlsson, JOG; Lundström, I | 1 |
| Black, P; Dear, JW; Gallagher, B; Grahamslaw, J; Henriksen, D; Lee, RJ; Morrison, EE; O'Brien, R; Oatey, K; Oosthuyzen, W; Weir, CJ | 1 |
| Karlsson, JOG | 1 |
| Dear, JW | 1 |
| Chan, WY; Hickey, EE; Hill, PB; Page, SW; Trott, DJ | 1 |
| Freeman, WE; Mullins, ME; Yeager, LH | 1 |
| Akakpo, JY; Jaeschke, H; Ramachandran, A | 1 |
4 review(s) available for acetylcysteine and edetic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Collagenase inhibitors: rationale for their use in treating corneal ulceration.
Topics: Acetylcysteine; alpha 1-Antitrypsin; alpha-Macroglobulins; Animals; Calcium; Corneal Ulcer; Cyclic AMP; Cysteine; Disease Models, Animal; Edetic Acid; Humans; Microbial Collagenase; Protease Inhibitors; Steroids; Tropocollagen; Zinc Radioisotopes | 1975 |
Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review.
Topics: Acetaminophen; Acetylcysteine; Acidosis; Animals; Antidotes; Cimetidine; Drug Overdose; Edetic Acid; Fomepizole; Humans; Mitochondria; Pyridoxal Phosphate | 2020 |
Novel strategies for the treatment of acetaminophen hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Edetic Acid; Fomepizole; Hepatocytes; Humans; Liver Failure, Acute; Pyridoxal Phosphate | 2020 |
2 trial(s) available for acetylcysteine and edetic acid
| Article | Year |
|---|---|
Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomi
Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Clinical Trials Data Monitoring Committees; Clinical Trials, Phase I as Topic; Data Interpretation, Statistical; Drug Overdose; Drug Therapy, Combination; Edetic Acid; Female; Humans; Male; Outcome Assessment, Health Care; Pyridoxal Phosphate; Randomized Controlled Trials as Topic; Research Design | 2019 |
Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial).
Topics: Acetaminophen; Acetylcysteine; Adult; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Overdose; Edetic Acid; Female; Humans; Male; Protective Agents; Pyridoxal Phosphate; Time Factors; Young Adult | 2019 |
35 other study(ies) available for acetylcysteine and edetic acid
| Article | Year |
|---|---|
Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis.
Topics: Biofilms; Carbon-13 Magnetic Resonance Spectroscopy; Drug Resistance, Bacterial; Drug Screening Assays, Antitumor; Halogens; HeLa Cells; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenazines; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship | 2016 |
An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.
Topics: Anti-Bacterial Agents; Biofilms; Cyclization; Halogenation; HeLa Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phenazines | 2018 |
EDTA effect on creatine kinase (CK) and on the SCE reagent.
Topics: Acetylcysteine; Calcium; Chelating Agents; Creatine Kinase; Drug Stability; Edetic Acid; Ferric Compounds; In Vitro Techniques; Indicators and Reagents; Isoenzymes; Mercaptoethanol; Scandinavian and Nordic Countries; Sulfhydryl Compounds; Time Factors | 1979 |
Therapeutic effects of heparin on Pseudomonas-induced corneal ulceration.
Topics: Acetylcysteine; Administration, Topical; Adult; Animals; Colistin; Corneal Ulcer; Drug Therapy, Combination; Edetic Acid; Gentamicins; Heparin; Humans; Male; Middle Aged; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits | 1976 |
Effects of ethylenediaminetetraacetate on "CK-NAC" reagent stability and measured creatine kinase activities.
Topics: Acetylcysteine; Creatine Kinase; Drug Stability; Edetic Acid; Enzyme Activation; Humans; Indicators and Reagents; Methods | 1977 |
Inhibition of creatine kinase activity by Ca2+ and reversing effect of ethylenediaminetetraacetate.
Topics: Acetylcysteine; Animals; Calcium; Creatine Kinase; Edetic Acid; Humans; Isoenzymes | 1978 |
Comparative effects of repeated parenteral administration of several chelators on the distribution and excretion of cobalt.
Topics: Acetylcysteine; Animals; Chelating Agents; Cobalt; Edetic Acid; Glutathione; Injections, Intraperitoneal; Male; Pentetic Acid; Rats; Rats, Inbred Strains; Succimer | 1988 |
Comparison of the effectiveness of several chelators after single administration on the toxicity, excretion and distribution of cobalt.
Topics: Acetylcysteine; Animals; Chelating Agents; Cobalt; Cysteine; Edetic Acid; Glutathione; Male; Mice; Pentetic Acid; Tissue Distribution | 1986 |
Interaction of lysine residues with the metal thiolate clusters in metallothionein.
Topics: Acetylcysteine; Amino Acids; Animals; Cadmium; Circular Dichroism; Edetic Acid; Kinetics; Liver; Lysine; Metallothionein; Nitrobenzenes; Protein Conformation; Rats; Trinitrobenzenesulfonic Acid; Zinc | 1985 |
The appropriate use of mucolytic agents.
Topics: Acetylcysteine; Anti-Bacterial Agents; Ascorbic Acid; Bronchi; Bronchitis; Bronchodilator Agents; Deoxyribonucleases; DNA; Edetic Acid; Epithelium; Glycosaminoglycans; Humans; Mucus; Peptide Hydrolases; Respiratory Therapy; Sputum; Trachea; Urea; Viscosity | 1970 |
Corneal toxicity of collagenase inhibitors.
Topics: Acetylcysteine; Animals; Calcium; Cornea; Corneal Opacity; Cysteine; Edema; Edetic Acid; Hypertonic Solutions; Injections; Microbial Collagenase; Ophthalmic Solutions; Rabbits; Sodium; Sodium Chloride | 1973 |
Adverse reactions to N-acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Edetic Acid; Female; Humans; Male; Skin Tests; Time Factors; Urticaria | 1984 |
Activation of human creatine kinase isoenzymes by pH and various sulfhydryl and chelating agents.
Topics: Acetylcysteine; Chelating Agents; Creatine Kinase; Edetic Acid; Egtazic Acid; Enzyme Activation; Glycerol; Humans; Hydrogen-Ion Concentration; Isoenzymes; Mercaptoethanol; Sulfhydryl Compounds | 1981 |
Activity of creatine kinase in sera from healthy women, carriers of Duchenne muscular dystrophy and cord blood, determined by the "European" recommended method with NAC-EDTA activation.
Topics: Acetylcysteine; Adolescent; Adult; Creatine Kinase; Edetic Acid; Female; Fetal Blood; Genetic Carrier Screening; Humans; Kinetics; Middle Aged; Muscular Dystrophies; Pregnancy; Reference Values | 1981 |
Role of mucus in gastric mucosal injury induced by local ischemia/reperfusion.
Topics: Acetylcysteine; Alcian Blue; Animals; Chromium Radioisotopes; Diterpenes; Edetic Acid; Gastric Mucosa; Hexosamines; Ischemia; Male; Mucus; Periodic Acid-Schiff Reaction; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1995 |
Treatment of cystine stones: combined approach using open pyelolithotomy, percutaneous pyelolithotripsy, extracorporeal shock wave lithotripsy and chemolysis.
Topics: Acetylcysteine; Adolescent; Adult; Combined Modality Therapy; Cystine; Cystinuria; Edetic Acid; Female; Humans; Kidney Calculi; Kidney Pelvis; Lithotripsy; Stents; Therapeutic Irrigation; Tromethamine | 1993 |
Metal-catalyzed inactivation of bovine glucose-6-phosphate dehydrogenase--role of thiols.
Topics: Acetylcysteine; Adenosine Diphosphate; Animals; Cattle; Cysteine; Dipeptides; Edetic Acid; Enzyme Activation; Glucosephosphate Dehydrogenase; Glutathione; Hydrogen Peroxide; Hypoxanthine; Iron; Metals; Oxidation-Reduction; Sulfhydryl Compounds; Xanthine Oxidase | 1996 |
Inhibition of xanthine oxidase by pterins.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Edetic Acid; Ferric Compounds; Formazans; Hydrogen-Ion Concentration; Nitroblue Tetrazolium; Oxidation-Reduction; Pterins; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Superoxides; Time Factors; Uric Acid; Xanthine; Xanthine Oxidase | 1998 |
Protective action on human LDL against oxidation and glycation by four organosulfur compounds derived from garlic.
Topics: Acetylcysteine; Allyl Compounds; Amphotericin B; Antioxidants; Chelating Agents; Copper; Cysteine; Disulfides; Edetic Acid; Garlic; Glucose; Humans; Lipoproteins, LDL; Oxidation-Reduction; Sulfides; Sulfur Compounds; Superoxides; Xanthine Oxidase | 2003 |
Evaluation of various compounds to inhibit activity of matrix metalloproteinases in the tear film of horses with ulcerative keratitis.
Topics: Acetylcysteine; alpha 1-Antitrypsin; Animals; Corneal Ulcer; Doxycycline; Edetic Acid; Electrophoresis; Horse Diseases; Horses; Hydroxamic Acids; Image Processing, Computer-Assisted; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Protease Inhibitors; Tears | 2003 |
Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment.
Topics: Acetylcysteine; Alzheimer Disease; Analysis of Variance; Animals; Antioxidants; Astrocytes; Cerebral Cortex; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Male; Manganese; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Dietary rescue of fumble--a Drosophila model for pantothenate-kinase-associated neurodegeneration.
Topics: Acetylcysteine; Adenosine Triphosphate; Animal Feed; Animals; Ascorbic Acid; Carnitine; Cloning, Molecular; Creatine; Diet; Disease Models, Animal; Drosophila; Drosophila melanogaster; Edetic Acid; Ginkgo biloba; Heterozygote; Humans; Inosine; Iron; Mutation; Neurodegenerative Diseases; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Transgenes; Vitamin E | 2005 |
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Edetic Acid; Humans; Hydrogen Peroxide; Leukocytes; Mice; Oxidation-Reduction; Pyridoxal Phosphate; Reactive Oxygen Species | 2006 |
Potential relationship between glutathione metabolism and flocculation in the yeast Kluyveromyces lactis.
Topics: Acetylcysteine; Culture Media; Edetic Acid; Flocculation; Galactose; Glutathione; Glutathione Transferase; Kluyveromyces | 2007 |
Antioxidant and free radical scavenging properties of N-acetylcysteine amide (NACA) and comparison with N-acetylcysteine (NAC).
Topics: Acetylcysteine; Antioxidants; beta Carotene; Biphenyl Compounds; Chelating Agents; Dose-Response Relationship, Drug; Edetic Acid; Free Radical Scavengers; Free Radicals; Humans; Hydrazines; Hydrogen Peroxide; Linoleic Acid; Metals; Picrates; Sulfhydryl Compounds | 2008 |
Hydroxyl radical-induced oxidation of a phenolic C-linked 2'-deoxyguanosine adduct yields a reactive catechol.
Topics: Acetylcysteine; Catechols; Copper; Deoxyguanosine; DNA Adducts; Edetic Acid; Ferrous Compounds; Hydrogen Peroxide; Hydroxyl Radical; Phenols | 2012 |
Role of extracellular calcium and mitochondrial oxygen species in psychosine-induced oligodendrocyte cell death.
Topics: Acetylcysteine; Antioxidants; Calcium; Calcium Chelating Agents; Cell Death; Cell Line; Cell Survival; Culture Media; Cytosol; Edetic Acid; Humans; Mitochondria; Oligodendroglia; Psychosine; Reactive Oxygen Species | 2014 |
In Vitro Efficacy of Nonantibiotic Treatments on Biofilm Disruption of Gram-Negative Pathogens and an In Vivo Model of Infectious Endometritis Utilizing Isolates from the Equine Uterus.
Topics: Acetylcysteine; Animals; Anti-Infective Agents; Biofilms; Biomass; Disease Models, Animal; Edetic Acid; Endometritis; Female; Gram-Negative Bacteria; Horses; Hydrogen Peroxide; Luminescent Measurements; Microbial Viability; Staining and Labeling; Uterus | 2016 |
Comparison of the efficacy of various concentrations and combinations of serum, ethylenediaminetetraacetic acid, tetracycline, doxycycline, minocycline, and N-acetylcysteine for inhibition of collagenase activity in an in vitro corneal degradation model.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Collagenases; Cornea; Corneal Diseases; Disease Models, Animal; Dogs; Doxycycline; Edetic Acid; Horses; Matrix Metalloproteinase Inhibitors; Minocycline; Serum; Tetracycline | 2018 |
Cause of and countermeasures for oxidation of the cysteine-derived reagent used in the amino acid derivative reactivity assay.
Topics: Acetylcysteine; Allergens; Animal Testing Alternatives; Animals; Biological Assay; Copper; Edetic Acid; Ferric Compounds; Models, Chemical; Oxidation-Reduction; Skin | 2019 |
In vitro antimicrobial activity of seven adjuvants against common pathogens associated with canine otitis externa.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Anti-Infective Agents; Bacteria; Dogs; Drug Resistance, Multiple, Bacterial; Drug Synergism; Edetic Acid; Fungi; Laurates; Malassezia; Microbial Sensitivity Tests; Monoglycerides; Otitis Externa; Pseudomonas aeruginosa; Staphylococcus | 2019 |
Letter in response to: "Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: stud
Topics: Acetaminophen; Acetylcysteine; Drug Overdose; Edetic Acid; Humans; Pyridoxal Phosphate; Research Design | 2019 |
Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir?
Topics: Acetaminophen; Acetylcysteine; Edetic Acid; Humans; Pyridoxal Phosphate; Superoxide Dismutase | 2019 |
Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir? - Authors' reply.
Topics: Acetaminophen; Acetylcysteine; Edetic Acid; Humans; Pyridoxal Phosphate; Superoxide Dismutase | 2019 |
Biofilm production by pathogens associated with canine otitis externa, and the antibiofilm activity of ionophores and antimicrobial adjuvants.
Topics: Acetylcysteine; Animals; Anti-Infective Agents; Bacteria; Biofilms; Dog Diseases; Dogs; Edetic Acid; Enrofloxacin; Ionophores; Microbial Sensitivity Tests; Monensin; Otitis Externa; Pyrans | 2019 |