acetylcysteine and ebselen

acetylcysteine has been researched along with ebselen in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's4 (13.79)18.2507
2000's16 (55.17)29.6817
2010's7 (24.14)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Gustafson, DL; Pritsos, CA; Sokoloff, M1
Gustafson, DL; Pritsos, CA1
Berggren, M; Cotgreave, IA; Moldéus, PW; Sandy, MS; Smith, MT1
Gryglewski, RJ; Hatchett, RJ; Młochowski, J; Radziszewski, W; Zembowicz, A1
Kondo, H; Niki, E; Takahashi, M1
Garrido, R; Hennig, B; Malecki, A; Mattson, MP; Toborek, M1
Ong, CN; Shen, HM; Yang, CF1
Finkel, T; Nemoto, S1
Gauthier, ER; Guérin, PJ1
Griendling, KK; Rocic, P; Seshiah, P1
Dechert, MA; Gerthoffer, WT; Griendling, KK; Rocic, P; Seshiah, PN; Taniyama, Y; Weber, DS1
Dehnade, F; Li, WQ; Liacini, A; Qureshi, HY; Zafarullah, M1
De Martino, L; Florio, S; Gabellini, C; Giordano, A; Iovane, G; Marsili, S; Montagnaro, S; Pacelli, F; Pacilio, M; Pagnini, U; Rocco, D1
Holland, SM; Kishida, KT; Klann, E; Pao, M1
Kil, J; Lynch, ED1
Kozhukhar, AV; Sumbayev, VV; Yasinska, IM1
Ezeamuzie, CI; Taslim, N1
Arai, Y; Arakawa, M; Ishige, K; Ishimura, A; Ito, Y; Kawabe, K; Suzuki, S1
Kurashima, Y; Ogura, T; Sakagami, H; Sugiyama, K; Tajima, M1
Brown, GC; Brown, RD; Burke, GA1
Arrais-Silva, WW; Colhone, MC; Degrossoli, A; Gadelha, FR; Giorgio, S; Joazeiro, PP1
Akgul, OE; Cakir, E; Cayci, T; Kizilgun, M; Kunak, ZI; Kurt, YG; Macit, E; Ozcan, A; Ozkan, E; Oztas, Y; Poyrazoglu, Y; Taslipinar, MY; Turker, T; Yaman, H; Yaren, H1
Campbell, KC; Giordano, P; Hatzopoulos, S; Kochanek, K; Laurell, G; Lorito, G; Martini, A; Petruccelli, J; Skarzynski, H; Sliwa, L1
Cho, JS; Kim, TH; Lee, HM; Lee, SH; Moon, YM; Park, IH; Park, SJ1
Rajguru, R1
Kumar, S; Li, X; Lockyer, P; Patterson, C; Pi, X; Portbury, AL; Xie, L1

Reviews

2 review(s) available for acetylcysteine and ebselen

ArticleYear
Compounds for the prevention and treatment of noise-induced hearing loss.
    Drug discovery today, 2005, Oct-01, Volume: 10, Issue:19

    Topics: Acetylcysteine; Allopurinol; Azoles; Glutathione Peroxidase; Hearing Loss, Noise-Induced; Humans; Isoindoles; Magnesium; Noise, Occupational; Organoselenium Compounds

2005
Military aircrew and noise-induced hearing loss: prevention and management.
    Aviation, space, and environmental medicine, 2013, Volume: 84, Issue:12

    Topics: Acetylcarnitine; Acetylcysteine; Aerospace Medicine; Aircraft; Anti-Inflammatory Agents; Antioxidants; Azoles; Creatine; Ear Protective Devices; Equipment Design; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Genetic Therapy; Hair Cells, Auditory; Head Protective Devices; Hearing Loss, Noise-Induced; Humans; Hyperbaric Oxygenation; Isoindoles; Magnesium; Methionine; Military Personnel; Nanomedicine; Neuroprotective Agents; Organoselenium Compounds; Regeneration; Resveratrol; Salicylic Acid; Stilbenes; Vitamins

2013

Other Studies

27 other study(ies) available for acetylcysteine and ebselen

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
PZ-51 (Ebselen) in vivo protection against adriamycin-induced mouse cardiac and hepatic lipid peroxidation and toxicity.
    Biochemical pharmacology, 1992, Aug-18, Volume: 44, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Azoles; Body Weight; Chemical and Drug Induced Liver Injury; Creatine Kinase; Doxorubicin; Drug Interactions; Female; Heart Diseases; Isoindoles; Lipid Peroxidation; Liver Diseases; Mice; Mice, Inbred BALB C; Organoselenium Compounds

1992
Inhibition of mitomycin C's aerobic toxicity by the seleno-organic antioxidant PZ-51.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:3

    Topics: Acetylcysteine; Aerobiosis; Animals; Antineoplastic Agents; Antioxidants; Azoles; Cell Hypoxia; Cell Line; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Isoindoles; Mice; Mitomycin; Mitomycins; Organoselenium Compounds; Porfiromycin; Selenium; Tumor Cells, Cultured

1991
N-acetylcysteine and glutathione-dependent protective effect of PZ51 (Ebselen) against diquat-induced cytotoxicity in isolated hepatocytes.
    Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18

    Topics: Acetylcysteine; Animals; Azoles; Carmustine; Diquat; Glutathione; Hydrogen Peroxide; Isoindoles; Lipid Peroxides; Liver; Male; Organoselenium Compounds; Oxidation-Reduction; Pyridinium Compounds; Rats; Rats, Inbred Strains; Selenium

1987
Carboxyebselen a potent and selective inhibitor of endothelial nitric oxide synthase.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:1

    Topics: Acetylcholine; Acetylcysteine; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Azoles; Cattle; Cerebellum; Endothelium, Vascular; Female; Glutathione; Glutathione Peroxidase; In Vitro Techniques; Isoindoles; Male; Mice; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Organoselenium Compounds; Rabbits; Spleen; Sulfhydryl Compounds; Swine

1994
Peroxynitrite-induced hemolysis of human erythrocytes and its inhibition by antioxidants.
    FEBS letters, 1997, Aug-18, Volume: 413, Issue:2

    Topics: Acetylcysteine; Albumins; Amidines; Antioxidants; Azoles; Catalase; Chromans; Erythrocytes; Glutathione; Hematocrit; Hemolysis; Humans; Isoindoles; Molsidomine; Nitrates; Organoselenium Compounds; Uric Acid; Vitamin E

1997
4-Hydroxynonenal induces oxidative stress and death of cultured spinal cord neurons.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Apoptosis; Arachidonic Acid; Azoles; Calcium; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; DNA Fragmentation; Fetus; Isoindoles; Lipid Peroxidation; Mice; Neurons; Organoselenium Compounds; Oxidative Stress; Spinal Cord

2000
Intracellular thiol depletion causes mitochondrial permeability transition in ebselen-induced apoptosis.
    Archives of biochemistry and biophysics, 2000, Aug-15, Volume: 380, Issue:2

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Azoles; Buthionine Sulfoximine; Calcium; Caspase 3; Caspase 9; Caspases; Cyclosporine; Cytochrome c Group; Egtazic Acid; Humans; Isoindoles; Membrane Potentials; Mitochondria, Liver; Organoselenium Compounds; Permeability; Sulfhydryl Compounds; Superoxide Dismutase; Superoxides; Tumor Cells, Cultured

2000
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway.
    Science (New York, N.Y.), 2002, Mar-29, Volume: 295, Issue:5564

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Azoles; Blood; Cells, Cultured; Culture Media; DNA-Binding Proteins; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Free Radical Scavengers; Humans; Hydrogen Peroxide; Isoindoles; Mice; Mutation; Nerve Tissue Proteins; Organoselenium Compounds; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Transcription Factors; Transfection

2002
Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen.
    Journal of cellular biochemistry, 2003, May-01, Volume: 89, Issue:1

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Azoles; Caspases; Cell Death; Cycloheximide; Cysteine Proteinase Inhibitors; Glutathione Peroxidase; Hybridomas; Isoindoles; Mice; Necrosis; Organoselenium Compounds

2003
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells.
    The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38

    Topics: Acetylcysteine; Angiotensin II; Animals; Aorta; Azoles; Blotting, Western; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genes, Dominant; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Muscle, Smooth, Vascular; Okadaic Acid; Onium Compounds; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Pyridines; Rats; Reactive Oxygen Species; Serine; Threonine; Time Factors

2003
Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration.
    Circulation research, 2004, May-14, Volume: 94, Issue:9

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Acetylcysteine; Animals; Aorta, Thoracic; Azoles; Becaplermin; Cell Movement; Cells, Cultured; Enzyme Activation; Humans; Isoindoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organoselenium Compounds; p21-Activated Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-sis; rac GTP-Binding Proteins; Rats; Reactive Oxygen Species; Receptors, Platelet-Derived Growth Factor; Recombinant Fusion Proteins; Signal Transduction; src-Family Kinases

2004
Transforming growth factor Beta1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species.
    Free radical biology & medicine, 2004, Jul-15, Volume: 37, Issue:2

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Azoles; Blotting, Northern; Blotting, Western; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Culture Media, Serum-Free; Cycloheximide; DNA-Binding Proteins; Down-Regulation; Free Radicals; Growth Substances; Humans; Hydrogen Peroxide; Isoindoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Oligonucleotides, Antisense; Organoselenium Compounds; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; RNA; RNA, Messenger; Signal Transduction; Smad2 Protein; Species Specificity; Time Factors; Tissue Inhibitor of Metalloproteinase-3; Trans-Activators; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
The involvement of oxidative stress in bovine herpesvirus type 4-mediated apoptosis.
    Frontiers in bioscience : a journal and virtual library, 2004, Sep-01, Volume: 9

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Azoles; Butylated Hydroxyanisole; Cattle; Cell Line; Cell Proliferation; Coloring Agents; DNA Fragmentation; Herpesvirus 4, Bovine; Isoindoles; Kidney; Models, Statistical; Organoselenium Compounds; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles

2004
NADPH oxidase is required for NMDA receptor-dependent activation of ERK in hippocampal area CA1.
    Journal of neurochemistry, 2005, Volume: 94, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcysteine; Animals; Azoles; Blotting, Western; Catalase; Catecholamines; Dopamine Agonists; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Hippocampus; Imidazolines; In Vitro Techniques; Isoindoles; Lysine; Metalloporphyrins; Mice; Mice, Inbred C57BL; N-Methylaspartate; NADPH Oxidases; Neurons; NG-Nitroarginine Methyl Ester; Organoselenium Compounds; Patch-Clamp Techniques; Phosphorylation; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase

2005
Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron.
    Biochimie, 2006, Volume: 88, Issue:5

    Topics: Acetylcysteine; Azoles; Cell Hypoxia; Cell Line; Glutathione; Humans; Hypoxia-Inducible Factor 1; Iron; Isoindoles; Ketoglutaric Acids; Mitochondria; Mitochondrial Proteins; Models, Biological; Nitric Oxide; Nitric Oxide Donors; Organoselenium Compounds; S-Nitrosoglutathione; Signal Transduction; Succinate Dehydrogenase

2006
Reactive oxygen species mediate phorbol ester-stimulated cAMP response in human eosinophils.
    European journal of pharmacology, 2006, Aug-14, Volume: 543, Issue:1-3

    Topics: Acetophenones; Acetylcysteine; Antioxidants; Azoles; Catalase; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Free Radical Scavengers; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Humans; Hydrogen Peroxide; Isoindoles; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Onium Compounds; Organoselenium Compounds; Oxidants; Protein Kinase C; Reactive Oxygen Species; Superoxide Dismutase; Tetradecanoylphorbol Acetate

2006
N-Acetylcysteine and ebselen but not nifedipine protected cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death.
    Neuroscience research, 2007, Volume: 57, Issue:2

    Topics: Acetylcysteine; Aldehydes; Animals; Animals, Newborn; Azoles; Calcium; Cell Death; Cells, Cultured; Cerebellum; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Isoindoles; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Nifedipine; Organoselenium Compounds; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors

2007
The redox state of glutathione regulates the hypoxic induction of HIF-1.
    European journal of pharmacology, 2009, Mar-15, Volume: 606, Issue:1-3

    Topics: Acetylcysteine; Animals; Azoles; Cell Line, Tumor; Enzyme Inhibitors; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Isoindoles; Organoselenium Compounds; Oxidation-Reduction; RNA, Messenger; Transcriptional Activation; Vascular Endothelial Growth Factor A

2009
Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine.
    Free radical biology & medicine, 2009, Apr-15, Volume: 46, Issue:8

    Topics: Acetylcysteine; Antioxidants; Arginase; Arginine; Ascorbic Acid; Azoles; Catalase; Cell Death; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen Peroxide; Isoindoles; Leukemia; Organoselenium Compounds

2009
The influence of low oxygen on macrophage response to Leishmania infection.
    Scandinavian journal of immunology, 2011, Volume: 74, Issue:2

    Topics: Acetylcysteine; Animals; Azoles; Basic Helix-Loop-Helix Transcription Factors; Female; Free Radical Scavengers; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-10; Interleukin-12; Isoindoles; Leishmaniasis, Cutaneous; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Organoselenium Compounds; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2011
Beneficial effects of N-acetylcysteine and ebselen on renal ischemia/reperfusion injury.
    Renal failure, 2011, Volume: 33, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Azoles; Drug Evaluation, Preclinical; Drug Therapy, Combination; Free Radical Scavengers; Isoindoles; Male; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2011
Dose-dependent protection on cisplatin-induced ototoxicity - an electrophysiological study on the effect of three antioxidants in the Sprague-Dawley rat animal model.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:8

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Auditory Threshold; Azoles; Cisplatin; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory, Outer; Isoindoles; Male; Methionine; Models, Animal; Organoselenium Compounds; Otoacoustic Emissions, Spontaneous; Rats; Rats, Sprague-Dawley

2011
Role of reactive oxygen species in transforming growth factor beta1-induced alpha smooth-muscle actin and collagen production in nasal polyp-derived fibroblasts.
    International archives of allergy and immunology, 2012, Volume: 159, Issue:3

    Topics: Acetylcysteine; Actins; Adult; Azoles; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; Collagen Type I; Collagen Type IV; Female; Fibroblasts; Fluoresceins; Fluorescent Dyes; Gene Expression; Humans; Isoindoles; Male; Microscopy, Fluorescence; NADPH Oxidase 4; NADPH Oxidases; Nasal Polyps; Onium Compounds; Organoselenium Compounds; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta1

2012
NADPH oxidase-generated reactive oxygen species are required for stromal cell-derived factor-1α-stimulated angiogenesis.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:9

    Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Azoles; Cattle; Cell Movement; Chemokine CXCL12; Dual-Specificity Phosphatases; Endothelial Cells; Endothelium, Vascular; Gene Knockdown Techniques; Hyperglycemia; Isoenzymes; Isoindoles; Membrane Proteins; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase Phosphatases; NADPH Oxidases; Neovascularization, Physiologic; Organoselenium Compounds; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction

2014