acetylcysteine has been researched along with dithiothreitol in 99 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (17.17) | 18.7374 |
| 1990's | 27 (27.27) | 18.2507 |
| 2000's | 33 (33.33) | 29.6817 |
| 2010's | 21 (21.21) | 24.3611 |
| 2020's | 1 (1.01) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, L; Chen, Q; Han, J; He, L; Huang, L; Li, B; Liu, H; Liu, X; Ma, K | 1 |
| Gobert, JG; Risack, LE; Vandevelde, ME | 1 |
| Gervasi, JP; Miller, NG | 1 |
| Eisenbart, J; Fless, GM; Hinman, J; Makino, K; Pfaffinger, D; Scanu, AM | 1 |
| Birkett, DJ; Lelo, A; Miners, JO | 1 |
| Abbott, V; Deloria, LB; Mannering, GJ | 1 |
| Bast, A; Haenen, GR; Timmerman, H; Vermeulen, NP | 1 |
| Burnett, D; Morrison, HM; Stockley, RA | 1 |
| de Jong, JM; den Hartog Jager, WA; Timmer, JG; Vyth, A | 1 |
| Frei, RW; Halvax, JJ; Kok, WT | 1 |
| Harman, AW; Self, G | 1 |
| Farber, JL; Hoek, JB; Starke, PE | 1 |
| Barrett-Bee, K; Cox, A; Davis, SS; Marriott, C; Readman, AS | 1 |
| Kaplan, W; Reep, BR | 2 |
| Macdonald, J | 1 |
| Lightowler, JE; Lightowler, NM | 1 |
| Barry, BK; Edwards, JC; Gruetter, CA; Gruetter, DY; Ignarro, LJ | 1 |
| Brown, DT; Marsh, RR; Wetmore, RF | 1 |
| Litt, M; Marriott, C; Martin, R | 1 |
| Das, KC; Lewis-Molock, Y; White, CW | 1 |
| Faye, I; Sun, SC | 1 |
| Abello, PA; Buchman, TG; Fidler, SA | 1 |
| Abello, PA; Buchman, TG | 1 |
| Dröge, W; Galter, D; Mihm, S | 1 |
| Barr, SG; Harrison, JJ; Racz, WJ; Rafeiro, E | 1 |
| Biaglow, JE; Held, KD | 1 |
| Finegold, M; Henning, SJ; Jacomino, M; Lau, C; Sandberg, JW | 1 |
| Klee, S; Nürnberger, MC; Ungemach, FR | 1 |
| Deneer, HG; Knight, I | 1 |
| Grewal, KK; Racz, WJ | 1 |
| Baraban, JM; Hardwick, JM; Lee, SH; Lin, KI; Narayanan, R; Ratan, RR | 1 |
| Abeles, AJ; Block, ER; Patel, JM | 1 |
| Hoener, B; Shen, W | 1 |
| Hochman, A; Melamed, E; Offen, D; Sternin, H; Ziv, I | 1 |
| Bossuyt, PM; de Jong, JM; Louwerse, ES; Timmer, JG; Vyth, A | 1 |
| Ikuta, K; Kameoka, M; Kimura, T; Okada, Y; Tobiume, M | 1 |
| Danne, M; Dickerson, JA; Rovin, BH; Tan, LC; Wilmer, WA | 1 |
| Campbell, NF; Gibson, XA; Goodman, SR; McIntyre, J; Monteiro, CA; Shah, A; Shartava, A; Zhang, Y | 1 |
| Katagiri, Y; Nakamura, M; Nakashima, S; Nozawa, Y | 1 |
| Cunnick, JM; Dorsey, JF; Mei, L; Wu, J | 1 |
| Paine, AJ; Rodriguez-Ariza, A | 1 |
| Adeli, K; Cavallo, D; Macri, J; Mohammadi, A; Rudy, D | 1 |
| Metodiewa, D; Winterbourn, CC | 1 |
| Drobny, H; Hellmann, G; Suko, J | 1 |
| Hirata, H; Kamata, H; Kamata, K; Oka, S; Yagisawa, H | 1 |
| Baquer, NZ; Genet, S; Kale, RK | 1 |
| Barzilai, A; Melamed, E; Shina, R; Shirvan, A; Ziv, I | 1 |
| Herman, TS; Martinez, BR; Meltz, ML; Mohan, S; Natarajan, M | 1 |
| Courteau, J; Kocsis-Bédard, S; Niyonsenga, T; Paquette, B; Thibodeau, PA | 1 |
| Andersson, A; Hultberg, B; Isaksson, A | 3 |
| Brera, B; de Ceballos, ML; Fernández-Tomé, MP | 1 |
| Alessio, M; Arese, P; Bussolino, F; Ferrandi, C; Gruarin, P; Primo, L; Tandon, NN; Ulliers, D | 1 |
| Chan, C; Goldkorn, T; Kawcak, T; Lavrentiadou, SN; Rasooly, R; Ravid, T; Tsaba, A; van der Vliet, A | 1 |
| Benet, LZ; Grillo, MP | 1 |
| Bae, I; Bae, JH; Baek, WK; Cho, CH; Cho, JW; Kim, KM; Kwon, TK; Lee, JE; Park, JW; Song, DK; Suh, MH; Suh, SI | 1 |
| Abdel-Naim, AB; Mohamadin, AM | 1 |
| Hultberg, B | 1 |
| Jackson, W; Kumar, KS; Seed, TM; Singh, VK | 1 |
| Chen, K; Feng, H; Wang, X; Zhang, M | 1 |
| Behar, TN; Colton, CA | 1 |
| Wang, H; Xu, H; Yang, X; Zhang, Z | 1 |
| Chaung, RH; Tung, LC; Wang, YC | 1 |
| Sadek, HA; Szweda, LI; Szweda, PA | 1 |
| Akhand, AA; Dai, Y; Du, J; Hayakawa, A; Hossain, K; Nakashima, I; Rifa'i, M; Suzuki, H; Takeda, K; Tsuboi, H | 1 |
| Arcelli, D; Barbieri, A; Capitani, S; Corbacella, E; Francioso, F; Giuffrè, S; Hatzopoulos, S; Lanzoni, I; Magosso, S; Martini, A; Previati, M; Volinia, S | 1 |
| Deshpande, VS; Kehrer, JP | 1 |
| Luchese, C; Nogueira, CW; Rocha, JB; Santos, FW; Zeni, G | 1 |
| Beshire, M; Dubach, JM; Naik, HB; Soybel, DI; Walsh, BM; Wieland, AM | 1 |
| Cho, YS; Choi, SO; Kim, HL; Park, JW | 1 |
| Baek, MW; Kim, DJ; Lee, BH; Lee, HK; Lee, HY; Na, YR; Noh, KJ; Park, JH; Park, SH; Ryu, DY; Seok, SH | 1 |
| Zhang, J | 1 |
| Chilian, WM; Dick, GM; Kiyooka, T; Park, Y; Rocic, P; Rogers, PA; Saitoh, S; Swafford, A; Viswanathan, C; Zhang, C | 1 |
| Andrade, FH; Bruton, JD; Dahlstedt, AJ; Katz, A; Larsson, NG; Place, N; Silva, JP; Westerblad, H; Yamada, T; Zhang, SJ | 1 |
| Jeong, E; Kim, SY; Kim, YS; Lee, JY; Park, ZY | 1 |
| Akhand, AA; Hamada, M; Hoque, MA; Hossain, K; Kato, M; Kawamoto, Y; Nakashima, I; Tsuboi, H; Yanagishita, T | 1 |
| Altman, JK; Dolniak, B; Glaser, H; Goussetis, DJ; Kroczynska, B; McNeer, JL; Platanias, LC; Sassano, A | 1 |
| Joshi, D; Mittal, DK; Shrivastava, S; Shukla, S | 1 |
| Bueno, AL; Goemann, IM; Larsen, PR; Maia, AL; Wajner, SM | 1 |
| Chung, HY; Jeong, HO; Li, C; Liu, XX; Park, D; Sun, S; Zhou, HM | 1 |
| Chen, J; Chen, L; Chen, Z; Li, J; Liao, C; Zhou, N | 1 |
| De Vecchi, E; Drago, L; Mattina, R; Romanò, CL; Signori, V | 1 |
| Akatov, VS; Faskhutdinova, AA; Solovyev, VV; Solovyeva, ME | 1 |
| Dai, J; Dai, K; Du, J; Liu, G; Wang, X; Yan, R; Zhang, F; Zhang, P; Zhang, Y; Zhao, L | 1 |
| Joshi, D; Mittal, DK; Shukla, S; Srivastav, AK; Srivastav, SK | 1 |
| May, JM; Meredith, ME; Qu, ZC | 1 |
| Adamus, J; Dębski, D; Kalyanaraman, B; Marcinek, A; Michałowski, B; Sikora, A; Smulik, R; Zielonka, J | 1 |
| Jayasree, K; Sara George, P; Saraswathy Veena, V; Sujathan, K | 1 |
| Kim, ND; Lee, BH; Lee, JY | 1 |
| Heidari, R; Najibi, A; Niknahad, H; Rahimi, HR; Shirazi Yeganeh, B; Taheri, V | 1 |
| Deponte, M; Krafczyk, J; Staudacher, V; Wezena, CA | 1 |
| Gessner, A; Held, I; Jantsch, J; Köstler, J; Schmidt, B; Simon, M; Teichmann, L | 1 |
| Boucher, RC; Delion, MF; Donaldson, SH; Ehre, C; Esther, CR; Fontana, NC; Grubb, BR; Hill, DB; Hothem, LN; Kato, T; Livraghi-Butrico, A; Markovetz, MR; Morrison, CB; Rushton, ZL; Thelin, WR; Villalon, D; Wang, B | 1 |
| Hori, M; Okazaki, Y; Tanaka, H; Toyokuni, S | 1 |
| Akhter, MS; Barabutis, N; Uddin, MA | 1 |
| Chen, JG; Guan, XL; Wang, F; Wu, PF | 1 |
| Brimacombe, KR; Dulcey, AE; Goldsborough, AS; Gottesman, MM; Griffiths, G; Hall, MD; Handley, MD; Kannan, P; Pluchino, KM | 1 |
1 trial(s) available for acetylcysteine and dithiothreitol
| Article | Year |
|---|---|
Survival in patients with amyotrophic lateral sclerosis, treated with an array of antioxidants.
Topics: Acetylcysteine; Administration, Oral; Amyotrophic Lateral Sclerosis; Antioxidants; Capsules; Chelating Agents; Dithioerythritol; Dithiothreitol; Free Radical Scavengers; Gastric Juice; Humans; Injections, Subcutaneous; Methionine; Succimer; Sulfhydryl Reagents; Survival Analysis | 1996 |
98 other study(ies) available for acetylcysteine and dithiothreitol
| Article | Year |
|---|---|
Identification of a new cyathane diterpene that induces mitochondrial and autophagy-dependent apoptosis and shows a potent in vivo anti-colorectal cancer activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Diterpenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
Effect of thiol derivatives on mixed mucus and blood clots in vitro.
Topics: Acetylcysteine; Blood Coagulation; Dithiothreitol; Expectorants; Humans; In Vitro Techniques; Mercaptoethanol; Mesna; Mucus; Respiratory System; Saline Solution, Hypertonic | 1978 |
Recovery of Cryptococcus neoformans from sputum using new technics for the isolation of fungi from sputum.
Topics: Acetylcysteine; Centrifugation; Cryptococcosis; Cryptococcus; Cryptococcus neoformans; Culture Media; Dithiothreitol; Humans; In Vitro Techniques; Methods; Pancreatin; Sputum; Trypsin | 1975 |
Attenuation of immunologic reactivity of lipoprotein(a) by thiols and cysteine-containing compounds. Structural implications.
Topics: Acetylcysteine; Apolipoproteins A; Apolipoproteins B; Blotting, Western; Cysteine; Dithiothreitol; Enzyme-Linked Immunosorbent Assay; Homocysteine; Humans; Lipoprotein(a); Lipoproteins; Male; Mercaptoethanol; Molecular Structure; Sulfhydryl Compounds | 1992 |
Mechanism of formation of 6-amino-5-(N-methylformylamino)-1-methyluracil and 3,7-dimethyluric acid from theobromine in the rat in vitro: involvement of cytochrome P-450 and a cellular thiol.
Topics: Acetylcysteine; Animals; Cimetidine; Cysteine; Cytochrome P-450 Enzyme System; Dithiothreitol; Glutathione; Kinetics; Male; Metyrapone; Microsomes, Liver; Pyridines; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Theobromine; Uracil; Uric Acid | 1990 |
Role of xanthine oxidase in the interferon-mediated depression of the hepatic cytochrome P-450 system in mice.
Topics: Acetylcysteine; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Allylisopropylacetamide; Animals; Azacitidine; Carboxymethylcellulose Sodium; Cytochrome P-450 Enzyme Inhibitors; Dithiothreitol; Ethylmorphine-N-Demethylase; Interferons; Liver; Male; Mice; Phenobarbital; Poly I-C; Polylysine; Tungsten; Tungsten Compounds; Xanthine Dehydrogenase; Xanthine Oxidase | 1988 |
Effect of thiols on lipid peroxidation in rat liver microsomes.
Topics: Acetylcysteine; Animals; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; Penicillamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds | 1989 |
The effect of reducing agents on proteolytic enzymes and oxidation of alpha 1-proteinase inhibitor.
Topics: Acetylcysteine; alpha 1-Antitrypsin; Blood Proteins; Bronchitis; Dithiothreitol; Forced Expiratory Volume; Humans; Kinetics; Oxidation-Reduction; Peptide Hydrolases; Protease Inhibitors; Sputum | 1986 |
Attempted treatment of motor neuron disease with N-acetylcysteine and dithiothreitol.
Topics: Acetylcysteine; Amyotrophic Lateral Sclerosis; Dithiothreitol; Drug Evaluation; Drug Hypersensitivity; Drug Therapy, Combination; Humans; Muscular Atrophy; Prednisolone | 1987 |
Comparison of electrochemical detection methods in liquid chromatography for the determination of N-acetylcysteine in plasma.
Topics: Acetylcysteine; Chromatography, Liquid; Dithiothreitol; Electrochemistry; Indicators and Reagents | 1986 |
Comparison of the protective effects of N-acetylcysteine, 2-mercaptopropionylglycine and dithiothreitol against acetaminophen toxicity in mouse hepatocytes.
Topics: Acetaminophen; Acetylcysteine; Amino Acids, Sulfur; Animals; Cells, Cultured; Dithiothreitol; Glutathione; Liver; Male; Mice; Tiopronin | 1986 |
Calcium-dependent and calcium-independent mechanisms of irreversible cell injury in cultured hepatocytes.
Topics: Acetylcysteine; Animals; Calcium; Cell Survival; Cells, Cultured; Deferoxamine; Dithiothreitol; Glucose Oxidase; Glutathione; Homeostasis; Hydrogen Peroxide; Iron; Liver; Male; NADP; Onium Compounds; Phosphorylase a; Rats; Rats, Inbred Strains; Trityl Compounds; Vitamin K | 1986 |
A new mucotropic agent--in vitro and in vivo evaluation of 2-alpha-thenoylthiopropionylglycine (bronchoplus).
Topics: Acetylcysteine; Animals; Dithiothreitol; Expectorants; Glycine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Models, Biological; Mucus; Rheology; Sulfides; Swine; Swine, Miniature; Thiophenes; Time Factors; Viscosity | 1985 |
The use of N-acetyl-L-cysteine and dithiothreitol to process sputa for mycological and fluorescent antibody examinations.
Topics: Acetylcysteine; Aspergillus; Blastomyces; Candida; Coccidioides; Cryptococcus; Culture Media; Dithiothreitol; Fluorescent Antibody Technique; Fungi; Histoplasma; Humans; Lung Diseases, Fungal; Sporothrix; Sputum | 1972 |
Liquefaction of sputum by N-acetyl-l-cysteine and dithiothreitol.
Topics: Acetylcysteine; Bacteriological Techniques; Dithiothreitol; Humans; Mycobacterium; Sputum | 1972 |
The effect of newer tubercle bacillus digestion and decontamination procedures on fungi causing pulmonary diseases.
Topics: Acetylcysteine; Aspergillus fumigatus; Bacteriological Techniques; Benzalkonium Compounds; Blastomyces; Candida albicans; Cell Survival; Coccidioides; Culture Media; Dithiothreitol; Fungi; Histoplasma; Humans; Indicators and Reagents; Lung Diseases, Fungal; Mitosporic Fungi; Mycobacterium tuberculosis; Nocardia; Nocardia asteroides; Paracoccidioides; Sodium; Sodium Hydroxide; Sporothrix; Sputum | 1972 |
Comparative mucolytic studies on dithiothreitol, N-acetyl-cysteine and L-cysteine on human respiratory mucus in vitro and their effects on the rate of flow of mucus in the exposed trachea of the rat on topical application.
Topics: Acetylcysteine; Animals; Bronchi; Cysteine; Dithiothreitol; Humans; In Vitro Techniques; Irritants; Models, Biological; Mucus; Rats; Rheology; Stimulation, Chemical; Trachea; Viscosity | 1971 |
Possible involvement of S-nitrosothiols in the activation of guanylate cyclase by nitroso compounds.
Topics: Acetylcysteine; Animals; Cattle; Coronary Vessels; Cysteine; Dithiothreitol; Enzyme Activation; Ferricyanides; Glutathione; Guanylate Cyclase; Kinetics; Liver; Methemoglobin; Myoglobin; Nitroso Compounds; Protein Binding; Rats; S-Nitrosoglutathione; S-Nitrosothiols; Sulfhydryl Compounds; Thioglucosides; Valine | 1980 |
The action of mucolytic agents on respiratory mucins and the implications for secretory otitis media.
Topics: Acetylcysteine; Adolescent; Animals; Child; Dithiothreitol; Dogs; Expectorants; Humans; In Vitro Techniques; Infant; Male; Mucins; Otitis Media; Otitis Media with Effusion; Penicillamine; Viscosity | 1982 |
The effect of mucolytic agents on the rheologic and transport properties of canine tracheal mucus.
Topics: Acetylcysteine; Animals; Carbocysteine; Cysteine; Dithiothreitol; Dogs; Elasticity; Expectorants; In Vitro Techniques; Mucus; Potassium Iodide; Rana catesbeiana; Rheology; Trachea; Urea; Viscosity | 1980 |
Activation of NF-kappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells.
Topics: Acetylcysteine; Animals; Base Sequence; Dithiothreitol; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Mercaptoethanol; Molecular Probes; Molecular Sequence Data; NF-kappa B; Oxidation-Reduction; Rats; Reactive Oxygen Species; Sulfhydryl Compounds; Superoxide Dismutase; Transcription Factor AP-1; Tumor Cells, Cultured | 1995 |
Transcription of immune genes in the giant silkmoth, Hyalophora cecropia, is augmented by H2O2 and diminished by thiol reagents.
Topics: Acetylcysteine; Animals; Dithiothreitol; Gene Expression Regulation; Genes, Insect; Hydrogen Peroxide; Moths; Oxidation-Reduction; Transcription, Genetic | 1995 |
Thiol reducing agents modulate induced apoptosis in porcine endothelial cells.
Topics: Acetylcysteine; Animals; Aorta; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Free Radical Scavengers; Glutathione; Heat-Shock Proteins; Kinetics; Lipopolysaccharides; Swine | 1994 |
Heat shock-induced cell death in murine microvascular endothelial cells depends on priming with tumor necrosis factor-alpha or interferon-gamma.
Topics: Acetylcysteine; Animals; Aorta; Apoptosis; Cell Survival; Cells, Cultured; Dithiothreitol; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Hot Temperature; Interferon-gamma; Kinetics; Lipopolysaccharides; Mice; Mice, Inbred C3H; Microcirculation; Swine; Tumor Necrosis Factor-alpha | 1994 |
Modulation of transcription factor NF kappa B activity by intracellular glutathione levels and by variations of the extracellular cysteine supply.
Topics: Acetylcysteine; Animals; Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; HIV; HIV Infections; Humans; Kinetics; Macaca mulatta; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Sulfhydryl Compounds; T-Lymphocytes; Transcriptional Activation | 1995 |
Effects of N-acetylcysteine and dithiothreitol on glutathione and protein thiol replenishment during acetaminophen-induced toxicity in isolated mouse hepatocytes.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Dithiothreitol; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Mice; Sulfhydryl Compounds | 1994 |
Mechanisms for the oxygen radical-mediated toxicity of various thiol-containing compounds in cultured mammalian cells.
Topics: Acetylcysteine; Animals; Cell Line; Cell Survival; Copper; Cricetinae; Cricetulus; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Hydrogen Peroxide; Kinetics; Lung; Mercaptoethylamines; Oxidation-Reduction; Penicillamine; Radiation-Protective Agents; Sulfhydryl Compounds; Superoxides | 1994 |
Improving access to intestinal stem cells as a step toward intestinal gene transfer.
Topics: Acetylcysteine; Animals; Buffers; Dithiothreitol; Epithelial Cells; Expectorants; Gene Transfer Techniques; Intestinal Mucosa; Intestines; Ligation; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Stem Cells | 1994 |
The consequences of nitrofurantoin-induced oxidative stress in isolated rat hepatocytes: evaluation of pathobiochemical alterations.
Topics: Acetylcysteine; Animals; Carmustine; Deferoxamine; Dithiothreitol; Glutathione; Glutathione Reductase; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Nitrofurantoin; Oxidation-Reduction; Rats; Rats, Wistar; Stress, Physiological | 1994 |
Inhibition of the polymerase chain reaction by mucolytic agents.
Topics: Acetylcysteine; Dithiothreitol; Expectorants; Humans; Mycoplasma pneumoniae; Nucleic Acid Synthesis Inhibitors; Polymerase Chain Reaction; Sputum; Taq Polymerase | 1994 |
Intracellular calcium disruption as a secondary event in acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Animals; Calcium; Cell Membrane; Chelating Agents; Chemical and Drug Induced Liver Injury; Dithiothreitol; Fura-2; In Vitro Techniques; Male; Mice; Sulfhydryl Compounds | 1993 |
Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.
Topics: Acetylcysteine; Animals; Apoptosis; Base Sequence; Cell Nucleus; Chelating Agents; Dithiothreitol; DNA; Iron; Lipid Peroxidation; Male; Mercaptoethanol; Mice; Molecular Sequence Data; Neuroblastoma; NF-kappa B; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats; Sindbis Virus; Sulfhydryl Reagents; Thiocarbamates; Tumor Cells, Cultured | 1995 |
Nitric oxide exposure and sulfhydryl modulation alter L-arginine transport in cultured pulmonary artery endothelial cells.
Topics: Acetylcysteine; Acrolein; Animals; Arginine; Biological Transport; Cells, Cultured; Dithiothreitol; Endothelium, Vascular; Ethylmaleimide; L-Lactate Dehydrogenase; Lipid Peroxidation; Nitrates; Nitric Oxide; Nitrites; Penicillamine; Pulmonary Artery; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Swine | 1996 |
Mitigation of nitrofurantoin-induced toxicity in the perfused rat liver.
Topics: Acetylcysteine; Adenosine Monophosphate; Animals; Anti-Infective Agents, Urinary; Antidotes; Cell Death; Chelating Agents; Dithiothreitol; Egtazic Acid; Free Radical Scavengers; Free Radicals; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Nitrofurantoin; Oxidation-Reduction; Oxidative Stress; Penicillamine; Perfusion; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Sulfobromophthalein; Tiopronin | 1996 |
Prevention of dopamine-induced cell death by thiol antioxidants: possible implications for treatment of Parkinson's disease.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Dithiothreitol; Dopamine; Glutathione; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Rats; Sulfhydryl Compounds | 1996 |
Intracellular glutathione as a possible direct blocker of HIV type 1 reverse transcription.
Topics: Acetylcysteine; Aspartic Acid; Cysteine; Dithiothreitol; DNA, Viral; Glutathione; HIV Reverse Transcriptase; HIV-1; Humans; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Interleukin-1beta induction of mitogen-activated protein kinases in human mesangial cells. Role of oxidation.
Topics: Acetylcysteine; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Diamide; Dithiothreitol; Enzyme Activation; Enzyme Induction; Glomerular Mesangium; Humans; Hydrogen Peroxide; Interleukin-1; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Phosphoproteins; Phosphotyrosine; Protein Kinases; Recombinant Proteins | 1997 |
The efficacy of reducing agents or antioxidants in blocking the formation of dense cells and irreversibly sickled cells in vitro.
Topics: Acetylcysteine; Actins; Anemia, Sickle Cell; Antioxidants; Centrifugation, Density Gradient; Dithiothreitol; Erythrocyte Aggregation; Erythrocyte Count; Glutathione; Humans; In Vitro Techniques; Reducing Agents | 1998 |
Involvement of tyrosine phosphorylation in inhibition of fMLP-induced PLD activation by N-acetyl-L-cysteine in differentiated HL60 cells.
Topics: Acetylcysteine; Androstadienes; Cell Differentiation; Chelating Agents; Cysteine; Dithiothreitol; Enzyme Activation; Free Radical Scavengers; HL-60 Cells; Humans; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Oxidants; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorylation; Sulfhydryl Reagents; Tyrosine; Unithiol; Wortmannin | 1998 |
Reversible regulation of SHP-1 tyrosine phosphatase activity by oxidation.
Topics: Acetylcysteine; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; HeLa Cells; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Oxidation-Reduction; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Transfection | 1998 |
Rapid induction of NF-kappaB binding during liver cell isolation and culture: inhibition by L-NAME indicates a role for nitric oxide synthase.
Topics: Acetylcysteine; Animals; Antioxidants; Binding, Competitive; Cell Culture Techniques; Cell Separation; Cell Survival; Cells, Cultured; Chromans; Dithiothreitol; Enzyme Inhibitors; Liver; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Oligonucleotides; Protein Binding; Rats; Rats, Sprague-Dawley; Response Elements; Time Factors | 1999 |
Studies on degradative mechanisms mediating post-translational fragmentation of apolipoprotein B and the generation of the 70-kDa fragment.
Topics: Acetylcysteine; Apolipoproteins B; Carrier Proteins; Cell Line; Cysteine Endopeptidases; Dithiothreitol; Fluorenes; Humans; Hydrolysis; Isoindoles; Lactones; Multienzyme Complexes; Peptide Fragments; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational | 1999 |
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide.
Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Hydrogen Peroxide; Oxygen Consumption; Penicillamine; Reactive Oxygen Species; Sulfhydryl Compounds; Superoxides; Xanthine Oxidase | 1999 |
Activation and inhibition of purified skeletal muscle calcium release channel by NO donors in single channel current recordings.
Topics: Acetylcysteine; Animals; Calcium; Calcium Channel Blockers; Dithiothreitol; Glutathione; Hydrazines; Muscle, Skeletal; Nitric Oxide Donors; Nitroso Compounds; Organomercury Compounds; Oxidation-Reduction; Phenylmercury Compounds; Rabbits; Ryanodine Receptor Calcium Release Channel; S-Nitrosoglutathione; Sulfhydryl Compounds | 1999 |
N-acetylcysteine suppresses TNF-induced NF-kappaB activation through inhibition of IkappaB kinases.
Topics: Acetylcysteine; Biological Transport; Cell Nucleus; Dithiothreitol; Free Radical Scavengers; HeLa Cells; Humans; I-kappa B Kinase; NF-kappa B; NF-kappaB-Inducing Kinase; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Receptors, Tumor Necrosis Factor; TNF Receptor-Associated Factor 1; TNF Receptor-Associated Factor 2; Tumor Necrosis Factor-alpha | 2000 |
Effects of free radicals on cytosolic creatine kinase activities and protection by antioxidant enzymes and sulfhydryl compounds.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Brain; Catalase; Creatine Kinase; Cytosol; Diabetes Mellitus, Experimental; Dithiothreitol; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Free Radicals; Heart; Hydrogen Peroxide; Insulin; Muscle, Skeletal; Myocardium; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Xanthine; Xanthine Oxidase | 2000 |
Induction of neuronal apoptosis by Semaphorin3A-derived peptide.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Antioxidants; Apoptosis; Axons; Cell Survival; Cerebellum; Cerebral Cortex; Chick Embryo; Dithiothreitol; Dopamine; Dose-Response Relationship, Drug; Endothelial Growth Factors; Free Radical Scavengers; Ganglia, Sympathetic; In Situ Nick-End Labeling; Lymphokines; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neuroglia; Neurons; PC12 Cells; Peptide Fragments; Rats; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Antioxidant compounds interfere with the 3.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Colorimetry; Coloring Agents; Culture Media; Dithiothreitol; Kinetics; Melatonin; Mercaptoethanol; Oxidation-Reduction; Pyrrolidines; Pyrrolidonecarboxylic Acid; Reagent Kits, Diagnostic; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Thiazolidines; Thiocarbamates; Vitamin E | 2000 |
Thiols can either enhance or suppress DNA damage induction by catecholestrogens.
Topics: Acetylcysteine; Antioxidants; Copper; Dithiothreitol; DNA Damage; Drug Resistance, Neoplasm; Estradiol; Estrogens, Catechol; Glutathione; Hydrogen Peroxide; Kinetics; Methotrexate; NAD; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Thioctic Acid | 2001 |
Interaction of metals and thiols in cell damage and glutathione distribution: potentiation of mercury toxicity by dithiothreitol.
Topics: Acetylcysteine; Antioxidants; Copper; Dithiothreitol; Drug Synergism; Glutathione; HeLa Cells; Homocysteine; Humans; Hydrogen Peroxide; Hydroquinones; Mercury; Oxidation-Reduction; Sodium Selenite | 2001 |
Thiol redox status influences extracellular concentration of homocysteine in HeLa cell cultures.
Topics: Acetylcysteine; Copper; Dithiothreitol; Dose-Response Relationship, Drug; HeLa Cells; Homocysteine; Humans; Indicators and Reagents; Ions; Oxidation-Reduction; Oxygen; Phenanthrolines; Sulfhydryl Compounds | 2000 |
beta-Amyloid-induced cytotoxicity, peroxide generation and blockade of glutamate uptake in cultured astrocytes.
Topics: Acetylcysteine; Amyloid beta-Peptides; Astrocytes; Catalase; Cell Survival; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Free Radicals; Glutamic Acid; Humans; Neurons; Peptide Fragments; Peroxides; Time Factors; Vitamin E | 2001 |
Cytoadherence of Plasmodium falciparum-infected erythrocytes is mediated by a redox-dependent conformational fraction of CD36.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; CD36 Antigens; Cell Adhesion; Cell Line; Chemical Fractionation; COS Cells; Cysteine; Dithiothreitol; Endothelium, Vascular; Epitopes; Erythrocyte Aggregation; Erythrocytes; Humans; Molecular Sequence Data; Oxidation-Reduction; Plasmodium falciparum; Protein Conformation; Reducing Agents; U937 Cells | 2001 |
Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione.
Topics: Acetylcysteine; Amitrole; Annexin A5; Antioxidants; Apoptosis; Bronchi; Buthionine Sulfoximine; Catalase; Cells, Cultured; Ceramides; Diacylglycerol Kinase; Dithiothreitol; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; In Situ Nick-End Labeling; Mercaptoethanol; Microscopy, Fluorescence; Oxidation-Reduction; Oxidative Stress; Pulmonary Alveoli; Reactive Oxygen Species; Trachea | 2001 |
Studies on the reactivity of clofibryl-S-acyl-CoA thioester with glutathione in vitro.
Topics: Acetylcysteine; Acyl Coenzyme A; Acylation; Animals; Chromatography, High Pressure Liquid; Clofibric Acid; Dithiothreitol; Glutathione; Hydrogen-Ion Concentration; Rats; Spectrometry, Mass, Electrospray Ionization; Xenobiotics | 2002 |
Lipoic acid increases glutathione production and enhances the effect of mercury in human cell lines.
Topics: Acetylcysteine; Antioxidants; Dithiothreitol; Drug Synergism; Glutathione; HeLa Cells; Hepatocytes; Homocysteine; Humans; Mercury; Thioctic Acid | 2002 |
Pyrrolidine dithiocarbamate induces cyclooxygenase-2 expression in NIH 3T3 fibroblast cells.
Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Chelating Agents; Copper; Cyclooxygenase 2; Dinoprostone; Dithiothreitol; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Isoenzymes; Kinetics; Metals; Mice; Oxidants; Prostaglandin-Endoperoxide Synthases; Pyrrolidines; RNA, Messenger; Thiocarbamates | 2002 |
In vitro activation of dibromoacetonitrile to cyanide: role of xanthine oxidase.
Topics: Acetonitriles; Acetylcysteine; Catalase; Cyanides; Deferoxamine; Disinfection; Dithiothreitol; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Hypoxanthine; In Vitro Techniques; Oxidation-Reduction; Superoxide Dismutase; Water Pollutants, Chemical; Xanthine Oxidase | 2003 |
Modulation of extracellular homocysteine concentration in human cell lines.
Topics: Acetylcysteine; Amino Acid Transport Systems; Carcinoma, Hepatocellular; Copper; Cysteine; Dithiothreitol; Extracellular Fluid; HeLa Cells; Homocysteine; Humans; Oxidation-Reduction; Sulfhydryl Compounds; Sulfonic Acids; Tumor Cells, Cultured | 2003 |
Inhibition of LPS-induced nitric oxide production in RAW cells by radioprotective thiols.
Topics: Acetylcysteine; Amifostine; Animals; Cell Line; Cysteine; Disulfiram; Dithiothreitol; Lipopolysaccharides; Macrophages; Mercaptoethylamines; Mice; Nitric Oxide; Radiation-Protective Agents; Sulfhydryl Compounds | 2003 |
Nitric oxide alleviates oxidative damage in the green alga Chlorella pyrenoidosa caused by UV-B radiation.
Topics: Acetylcysteine; Ascorbic Acid; Catalase; Chlorella; Chlorophyll; Dithiothreitol; Glutathione; Nitric Oxide; Nitroprusside; Oxidative Stress; Phenylalanine Ammonia-Lyase; Superoxide Dismutase; Ultraviolet Rays | 2003 |
Redox regulation of neuronal migration in a Down Syndrome model.
Topics: Acetylcysteine; Animals; Chemotaxis; Disease Models, Animal; Dithiothreitol; Down Syndrome; Fetus; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Oxidation-Reduction; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; Trisomy | 2003 |
Both calcium and ROS as common signals mediate Na(2)SeO(3)-induced apoptosis in SW480 human colonic carcinoma cells.
Topics: Acetylcysteine; Aniline Compounds; Apoptosis; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Catalase; Cell Line, Tumor; Cell Size; Cell Survival; Cobalt; Colonic Neoplasms; Dithiothreitol; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; Fluoresceins; Glutathione; Humans; Membrane Potentials; Mitochondria; Reactive Oxygen Species; Ruthenium Red; Sodium Selenite; Xanthenes | 2003 |
Comparison of the cytotoxicity induced by different exposure to sodium arsenite in two fish cell lines.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Apoptosis; Arsenites; Cell Cycle; Cell Line; Cell Size; Cell Survival; Dithiothreitol; DNA Fragmentation; Epithelial Cells; Fibroblasts; Flow Cytometry; Fluorescent Antibody Technique; Microtubules; Sodium Compounds; Tilapia | 2004 |
Modulation of mitochondrial complex I activity by reversible Ca2+ and NADH mediated superoxide anion dependent inhibition.
Topics: Acetylcysteine; Animals; Anions; Calcium; Catalase; Detergents; Dithiothreitol; Dose-Response Relationship, Drug; Egtazic Acid; Electron Transport Complex I; Free Radicals; Hydrogen-Ion Concentration; Male; Mitochondria; NAD; Oxidants; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Superoxides; Time Factors | 2004 |
Paeoniflorin induces apoptosis of lymphocytes through a redox-linked mechanism.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Benzoates; Bridged-Ring Compounds; Caspases; Curcumin; Dithiothreitol; Enzyme Activation; Enzyme Inhibitors; Glucosides; Humans; Jurkat Cells; Lymphocytes; Membrane Potentials; Mice; Mitochondria; Mitogen-Activated Protein Kinases; Monoterpenes; Oxidation-Reduction; Paeonia; Phosphorylation; Reactive Oxygen Species | 2004 |
RNA expression induced by cisplatin in an organ of Corti-derived immortalized cell line.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Butylated Hydroxytoluene; Cell Line, Transformed; Cell Survival; Cisplatin; Cytoprotection; Dithiothreitol; Gene Expression; Malondialdehyde; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Organ of Corti; RNA; Time Factors | 2004 |
Oxidative stress-driven mechanisms of nordihydroguaiaretic acid-induced apoptosis in FL5.12 cells.
Topics: Acetylcysteine; Animals; Apoptosis; B-Lymphocytes; Caspase 3; Caspases; Cell Line; Cytochromes c; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Lipoxygenase Inhibitors; Masoprocol; Mice; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation | 2006 |
Cadmium inhibits delta-aminolevulinate dehydratase from rat lung in vitro: interaction with chelating and antioxidant agents.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Benzene Derivatives; Cadmium Chloride; Chelating Agents; Chlorides; Dithiothreitol; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Environmental Pollutants; Enzyme Inhibitors; Lung; Male; Organoselenium Compounds; Porphobilinogen Synthase; Rats; Rats, Wistar; Succimer; Unithiol; Zinc Compounds | 2007 |
Thiol-oxidant monochloramine mobilizes intracellular Ca2+ in parietal cells of rabbit gastric glands.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Calcium; Calcium Signaling; Calcium-Binding Proteins; Calcium-Transporting ATPases; Chelating Agents; Chloramines; Cytoplasm; Dithiothreitol; Dose-Response Relationship, Drug; Ethylenediamines; Fluorescent Dyes; Fura-2; In Vitro Techniques; Metals, Heavy; Microscopy, Fluorescence; Oxidants; Oxidation-Reduction; Oxidative Stress; Parietal Cells, Gastric; Rabbits; Sulfhydryl Compounds; Time Factors | 2007 |
ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPalpha and STAT-3.
Topics: Acetylcysteine; Animals; Antimicrobial Cationic Peptides; Blotting, Western; CCAAT-Enhancer-Binding Protein-alpha; Cell Hypoxia; Cell Line, Tumor; Dithiothreitol; Down-Regulation; Free Radical Scavengers; Gene Expression; Hepcidins; Humans; Hydrogen Peroxide; Hypoxia; Hypoxia-Inducible Factor 1; Mice; Mice, Inbred BALB C; Oxidants; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; STAT3 Transcription Factor; Transcription, Genetic | 2007 |
Arsenite-induced apoptosis is prevented by antioxidants in zebrafish liver cell line.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Arsenites; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Dithiothreitol; Dose-Response Relationship, Drug; Genes, Reporter; Green Fluorescent Proteins; HSP70 Heat-Shock Proteins; Humans; Liver; Oxidative Stress; Plasmids; Transfection; Trypan Blue; Zebrafish | 2007 |
Suppression of phosphoenolpyruvate carboxykinase gene expression by reduced endogenous glutathione level.
Topics: Acetylcysteine; Aging; Animals; Cell Line, Tumor; Diabetes Mellitus; Dithiothreitol; Energy Metabolism; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Gluconeogenesis; Glutathione; Hepatocytes; Homeostasis; Male; Obesity; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphoenolpyruvate Carboxykinase (ATP); Rats; Rats, Sprague-Dawley; RNA, Messenger | 2007 |
Redox-dependent coronary metabolic dilation.
Topics: Acetylcysteine; Animals; Antioxidants; Coronary Vessels; Culture Media, Conditioned; Dithiothreitol; Enzyme Activation; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Microscopy, Fluorescence; Myocytes, Cardiac; Nitroprusside; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Paracrine Communication; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; Reducing Agents; Sulfhydryl Compounds; Vasodilation; Vasodilator Agents | 2007 |
Reactive oxygen species and fatigue-induced prolonged low-frequency force depression in skeletal muscle fibres of rats, mice and SOD2 overexpressing mice.
Topics: Acetylcysteine; Animals; Antioxidants; Calcium; Dithiothreitol; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Rats; Reactive Oxygen Species; Sarcoplasmic Reticulum; Superoxide Dismutase | 2008 |
Alteration of Toll-like receptor 4 activation by 4-hydroxy-2-nonenal mediated by the suppression of receptor homodimerization.
Topics: Acetylcysteine; Aldehydes; Animals; Cell Line; Chemokine CCL5; Chemokine CXCL10; Dimerization; Dithiothreitol; Humans; Immunoblotting; Inflammation; Interferon-beta; Lipopolysaccharides; Mice; Phagocytosis; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2009 |
1,4-butanediyl-bismethanethiosulfonate (BMTS) induces apoptosis through reactive oxygen species-mediated mechanism.
Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspase 9; Dithiothreitol; DNA Fragmentation; Free Radical Scavengers; Humans; Jurkat Cells; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Thiosulfonic Acids | 2009 |
Arsenic trioxide-dependent activation of thousand-and-one amino acid kinase 2 and transforming growth factor-beta-activated kinase 1.
Topics: Acetylcysteine; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Dithiothreitol; Enzyme Activation; Genetic Variation; Hematopoietic Stem Cells; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; MAP Kinase Kinase Kinases; Oxides; Phosphorylation; Protein Kinases; Reactive Oxygen Species; RNA, Small Interfering; Tretinoin; U937 Cells | 2010 |
Protective role of thiol chelators against dimethylmercury induced toxicity in male rats.
Topics: Acetylcysteine; Animals; Brain; Chelating Agents; Disease Models, Animal; Dithiothreitol; Enzymes; Kidney; Lipid Peroxidation; Liver; Male; Mercury Poisoning, Nervous System; Methylmercury Compounds; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 2010 |
IL-6 promotes nonthyroidal illness syndrome by blocking thyroxine activation while promoting thyroid hormone inactivation in human cells.
Topics: Acetylcysteine; Cell Line; Cell Line, Tumor; Cytokines; Dithiothreitol; Glutathione; Humans; Interleukin-6; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Thyroid Diseases; Thyroid Hormones; Thyroxine | 2011 |
Hydrogen peroxide targets the cysteine at the active site and irreversibly inactivates creatine kinase.
Topics: Acetylcysteine; Anilino Naphthalenesulfonates; Binding Sites; Brain; Catalytic Domain; Creatine Kinase, BB Form; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Glutathione; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Protein Binding; Reactive Oxygen Species; Spectrometry, Fluorescence; Structure-Activity Relationship; Sulfhydryl Compounds | 2011 |
Synergy of glutathione, dithiothreitol and N-acetyl-L-cysteine self-assembled monolayers for electrochemical assay: sensitive determination of arsenic(III) in environmental and drinking water.
Topics: Acetylcysteine; Arsenic; Dithiothreitol; Drinking Water; Electrochemical Techniques; Electrodes; Glutathione; Gold; Limit of Detection; Seawater; Water Pollutants, Chemical | 2011 |
Does dithiothreitol improve bacterial detection from infected prostheses? A pilot study.
Topics: Acetylcysteine; Bacteria; Bacteriological Techniques; Biofilms; Dithiothreitol; Joint Prosthesis; Pilot Projects; Sonication; Time Factors | 2012 |
Thiol antioxidants in combination with vitamin B12 induce apoptotic death of human lymphocytic leukemia cells by destabilization of lysosomes with the involvement of iron ions.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Line, Tumor; Dithiothreitol; Glutathione; Humans; Iron; Lysosomes; Sulfhydryl Compounds; Vitamin B 12 | 2013 |
The role of intraplatelet reactive oxygen species in the regulation of platelet glycoprotein Ibα ectodomain shedding.
Topics: Acetylcysteine; Blood Platelets; Calcimycin; Calpain; Collagen; Dithiothreitol; Flow Cytometry; Humans; Platelet Glycoprotein GPIb-IX Complex; Reactive Oxygen Species; Thrombin | 2013 |
Methylmercury toxicity: amelioration by selenium and water-soluble chelators as N-acetyl cysteine and dithiothreitol.
Topics: Acetylcysteine; Animals; Brain; Chelating Agents; Dithiothreitol; Environmental Pollutants; Kidney; Liver; Male; Methylmercury Compounds; Oxidative Stress; Rats, Sprague-Dawley; Selenium Compounds; Solubility; Water | 2014 |
Ascorbate reverses high glucose- and RAGE-induced leak of the endothelial permeability barrier.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Benzamides; Cell Line; Cell Membrane Permeability; Cells, Cultured; Chromans; Cyclic N-Oxides; Dithiothreitol; Dose-Response Relationship, Drug; Endothelial Cells; Glucose; Glycation End Products, Advanced; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Mice; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin, Bovine; Spin Labels | 2014 |
Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.
Topics: Acetylcysteine; Algorithms; Animals; Boron Compounds; Boronic Acids; Captopril; Cattle; Chromatography, High Pressure Liquid; Coumarins; Cysteine; Dithiothreitol; Humans; Hydrogen Sulfide; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Chemical; Nitrogen Oxides; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Serum Albumin; Spectrophotometry; Sulfhydryl Compounds | 2014 |
Comparative analysis of cell morphology in sputum samples homogenized with dithiothreitol, N-acetyl-L cysteine, Cytorich(®) red preservative and in cellblock preparations to enhance the sensitivity of sputum cytology for the diagnosis of lung cancer.
Topics: Acetylcysteine; Cytodiagnosis; Dithiothreitol; DNA, Neoplasm; Early Detection of Cancer; Humans; Immunohistochemistry; Lung; Lung Neoplasms; Preservatives, Pharmaceutical; Sensitivity and Specificity; Sputum; Tumor Cells, Cultured | 2015 |
Celastrol blocks binding of lipopolysaccharides to a Toll-like receptor4/myeloid differentiation factor2 complex in a thiol-dependent manner.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Cytokines; Dithiothreitol; Enzyme-Linked Immunosorbent Assay; Lipopolysaccharides; Lymphocyte Antigen 96; Macrophages; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Pentacyclic Triterpenes; Polymerase Chain Reaction; Sulfhydryl Compounds; Toll-Like Receptor 4; Tripterygium; Triterpenes | 2015 |
Sulfasalazine-induced renal injury in rats and the protective role of thiol-reductants.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antirheumatic Agents; Dithiothreitol; Drug Evaluation, Preclinical; Free Radical Scavengers; Male; Random Allocation; Rats, Sprague-Dawley; Sulfasalazine | 2016 |
Growth inhibitory effects of standard pro- and antioxidants on the human malaria parasite Plasmodium falciparum.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Benzothiazoles; Diamide; Diamines; Dithiothreitol; Dose-Response Relationship, Drug; Erythrocytes; Fluorescent Dyes; Host-Parasite Interactions; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Malaria, Falciparum; Organic Chemicals; Oxidants; Oxidation-Reduction; Oxidative Stress; Parasitemia; Plasmodium falciparum; Quinolines; tert-Butylhydroperoxide; Time Factors | 2017 |
Liquillizer Does Not Interfere with Galactomannan Antigen Detection in Contrast to Dithiothreitol and
Topics: Acetylcysteine; Aspergillosis; Aspergillus; Bronchoalveolar Lavage Fluid; Dithiothreitol; Enzyme-Linked Immunosorbent Assay; Expectorants; Galactose; Humans; Mannans; Respiratory Tract Infections; Retrospective Studies | 2017 |
An Improved Inhaled Mucolytic to Treat Airway Muco-obstructive Diseases.
Topics: Acetylcysteine; Animals; Asthma; Cystic Fibrosis; Disease Models, Animal; Dithiothreitol; Expectorants; Humans; In Vitro Techniques; Male; Mice; Mucociliary Clearance; Mucus; Pulmonary Disease, Chronic Obstructive | 2019 |
l-Dehydroascorbic acid recycled by thiols efficiently scavenges non-thermal plasma-induced hydroxyl radicals.
Topics: Acetylcysteine; Ascorbic Acid; Cyclic N-Oxides; Dehydroascorbic Acid; Dithiothreitol; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Hydroxyl Radical; Plasma Gases; Spin Labels | 2019 |
Unfolded protein response regulates P53 expression in the pulmonary endothelium.
Topics: Acetylcysteine; Alkaloids; Animals; Brefeldin A; Cattle; Cells, Cultured; Dithiothreitol; Endothelium; Genes, p53; Pulmonary Artery; Thapsigargin; Unfolded Protein Response | 2019 |
N-acetylcysteine facilitates extinction of cued fear memory in rats via reestablishing basolateral amygdala glutathione homeostasis.
Topics: Acetylcysteine; Animals; Basolateral Nuclear Complex; Buthionine Sulfoximine; Conditioning, Classical; Cues; Dithiothreitol; Extinction, Psychological; Fear; Glutathione; Homeostasis; Male; Memory; Rats; Rats, Sprague-Dawley | 2022 |
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Orphan Drug Production; Paclitaxel; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tiopronin | 2011 |