acetylcysteine has been researched along with diethyl maleate in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (20.00) | 18.7374 |
| 1990's | 15 (37.50) | 18.2507 |
| 2000's | 10 (25.00) | 29.6817 |
| 2010's | 7 (17.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elias, MM; Girardi, G | 2 |
| Huang, HS; Jurima-Romet, M; Paul, CJ; Thomas, BH | 1 |
| Hayes, MA; Pollanen, MS; Quinn, BA; Wollenberg, GK | 1 |
| Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Sugimoto, T; Terano, A; Yoshida, H | 1 |
| Dehnen, W | 1 |
| Furukawa, T; Palacin, M; Perez, C; Viña, J; Viña, JR | 1 |
| Davis, ME; Droy, BF; Hinton, DE | 1 |
| Kaplowitz, N; Kuhlenkamp, J; Lu, SC; Robert, A | 1 |
| Chan, A; Landre, P; Marafino, BJ; Winkelhake, JL; Zimmerman, RJ | 1 |
| Budini, R; Fraticelli, A; Guarnieri, C; Vaona, I; Ventura, C | 1 |
| Mitchell, JB; Russo, A | 1 |
| Berman, ML; Harbison, RD; James, RC; Smith, AC | 1 |
| Anundi, I; Dawson, JR; Moldéus, P; Norbeck, K | 1 |
| Harada, T; Kuronuma, Y; Tamano, T; Yoshida, H | 1 |
| Flory, W; Tate, TM | 1 |
| Butterworth, M; Cohen, GM; Hobbs, M; Upshall, DG | 1 |
| Kawase, M; Kinoshita, C; Murata, H; Nakata, K; Ogata, K; Ogino, S; Ohmori, S; Sakaue, T | 1 |
| De Jager-Krikken, A; Jansen, PL; Kuipers, F; Leuvenink, R; Moshage, H; Tuyt, L; Van Goor, H; Vos, TA | 1 |
| Balasubramanian, KA; Benard, O; Madesh, M | 1 |
| Accorsi, K; Esposito, F; Porro, D; Russo, T; Vanoni, M; Wanke, V | 1 |
| Hahn, LJ; Jeng, JH; Kuo, MY; Kuo, YS; Tsai, CL; Yang, PJ | 1 |
| Agarwal, R; Shukla, GS | 1 |
| Beau, B; Croute, F; Gaubin, Y; Murat, J; Soleilhavoup, J; Vaissade, F | 1 |
| Cimino, F; Esposito, F; Russo, L; Russo, T | 1 |
| Brennan, P; Buckpitt, AR; Chichester, CH; Helton, C; Plopper, CG; Tyler, NK; West, JA | 1 |
| Baker, RD; Baker, SS; Gupta, A; Li, L; Rao, RK | 1 |
| Freitas, I; Griffini, P; Pietrocola, G; Richelmi, P; Vairetti, M | 1 |
| Chen, CJ; Liao, SL | 1 |
| Lee, YJ; Shukla, SD | 1 |
| Elmes, MJ; Gardner, DS; Langley-Evans, SC; McMullen, S | 1 |
| Harper, SL; Tanguay, RL; Usenko, CY | 1 |
| Hong, H; Ji, H; Li, WG; Li, YQ; Long, Y; Wang, Y; Wang, YY; Wu, J; Xia, YZ | 1 |
| Beckman, S; Drowley, L; Huard, J; Keller, B; Okada, M; Tobita, K; Vella, J | 1 |
| Kingsley, PJ; Stamm, CE; West, JD | 1 |
| Inomata, A; Nakae, D; Nakagawa, Y; Nakajima, K; Ogata, A; Suzuki, T | 1 |
| Chang, SW; Chung, JH; Kim, EC; Kim, YS; Lee, YM; Noh, K | 1 |
| Clemens, DL; Dey, A; Kumar, SM; Swaminathan, K | 1 |
| Hou, Y; Hu, CA; Hu, S; Long, M; Mei, H; Wang, L; Wu, G; Yan, L; Yi, D | 1 |
| Jin, B; Ondrejcak, T; Rowan, MJ; Zhang, D | 1 |
40 other study(ies) available for acetylcysteine and diethyl maleate
| Article | Year |
|---|---|
Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity.
Topics: Acetylcysteine; Animals; gamma-Glutamyltransferase; Glutathione; Kidney; Lipid Peroxidation; Liver; Male; Maleates; Mercuric Chloride; Mercury; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1991 |
Enalapril cytotoxicity in primary cultures of rat hepatocytes. II. Role of glutathione.
Topics: Acetylcysteine; Animals; Antimetabolites; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Drug Synergism; Enalapril; Glutathione; Glutathione Reductase; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred F344 | 1991 |
Reversible mitochondrial swelling in cultured rat hepatocytes exposed to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Acetylcysteine; Animals; Carmustine; Cell Survival; Cells, Cultured; Dimethylhydrazines; Glutathione; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Maleates; Methylhydrazines; Mitochondria, Liver; Pinocytosis; Rats; Rats, Inbred F344 | 1990 |
Protective role of intracellular glutathione against ethanol-induced damage in cultured rat gastric mucosal cells.
Topics: Acetylcysteine; Animals; Cells, Cultured; Chromium Radioisotopes; Diamide; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucosa; Glutathione; Male; Maleates; Oxidation-Reduction; Peroxides; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; tert-Butylhydroperoxide | 1990 |
A study on urinary thioethers by detecting N-acetylcysteine and thiophenol after alkaline hydrolysis.
Topics: Acetylcysteine; Animals; Benzene; Female; Humans; Hydrolysis; Maleates; Phenols; Rats; Reproducibility of Results; Smoking; Sulfhydryl Compounds | 1990 |
Effect of oral glutathione on hepatic glutathione levels in rats and mice.
Topics: Acetaminophen; Acetylcysteine; Adenosine Triphosphate; Animals; Cysteine; Fasting; Glutathione; Liver; Maleates; Methionine; Mice; Rats; Rats, Inbred Strains | 1989 |
Mechanism of allyl formate-induced hepatotoxicity in rainbow trout.
Topics: Acetylcysteine; Alanine Transaminase; Aldehyde Dehydrogenase; Animals; Dose-Response Relationship, Drug; Formates; Formic Acid Esters; Glutathione; Liver; Maleates; Sulfhydryl Compounds; Trout | 1989 |
Role of glutathione status in protection against ethanol-induced gastric lesions.
Topics: Acetylcysteine; Animals; Cysteamine; Ethanol; Gastric Mucosa; Glutathione; Male; Maleates; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Stomach Ulcer; Thiazoles; Thiazolidines | 1989 |
The role of oxidant injury in tumor cell sensitivity to recombinant human tumor necrosis factor in vivo. Implications for mechanisms of action.
Topics: Acetylcysteine; Animals; Female; Free Radicals; Glutathione; Humans; Lipid Peroxides; Maleates; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Oxygen; Rats; Rats, Inbred Strains; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1989 |
External GSSG enhances intracellular glutathione level in isolated cardiac myocytes.
Topics: Acetylcysteine; Animals; Carmustine; Cysteine; Glucose; Glutathione; Heart; Kinetics; Maleates; Myocardium; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1987 |
Thiols, thiol depletion, and thermosensitivity.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cricetinae; Cysteine; Glutathione; Heat-Shock Proteins; Hot Temperature; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Oxygen Consumption; Protein Biosynthesis; Sulfhydryl Compounds; Time Factors | 1983 |
Paradoxical effects of perturbation of intracellular levels of glutathione on halothane-induced hepatotoxicity in hyperthyroid rats.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Halothane; Hyperthyroidism; Liver; Male; Maleates; Rats; Sulfhydryl Compounds; Time Factors; Triiodothyronine | 1984 |
The effectiveness of N-acetylcysteine in isolated hepatocytes, against the toxicity of paracetamol, acrolein, and paraquat.
Topics: Acetaminophen; Acetone; Acetylcysteine; Acrolein; Aldehydes; Amino Acids; Animals; Cell Survival; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Maleates; Paraquat; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
Role of renal gamma-glutamyltransferase activity in hepatic utilization of exogenous glutathione.
Topics: Acetylcysteine; Animals; gamma-Glutamyltransferase; Glutathione; Injections, Intravenous; Isoxazoles; Kidney; Liver; Male; Maleates; Nephrectomy; Rats; Rats, Sprague-Dawley | 1995 |
Effect of different renal glutathione levels on renal mercury disposition and excretion in the rat.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Urea Nitrogen; Glutathione; Kidney; Male; Maleates; Mercuric Chloride; Rats; Rats, Wistar | 1993 |
Effect of 2-thiotriazone (TTZ) on hepatic and pulmonary glutathione (GSH) concentrations in rats.
Topics: Acetylcysteine; Animals; Female; Glutathione; Liver; Lung; Male; Maleates; Rats; Thiourea | 1993 |
Elevation of cysteine and replenishment of glutathione in rat lung slices by cysteine isopropylester and other cysteine precursors.
Topics: Acetylcysteine; Animals; Cysteine; Glutathione; Lung; Male; Maleates; Rats; Rats, Wistar | 1993 |
Effects of age on levels of cysteine, glutathione and related enzyme activities in livers of mice and rats and an attempt to replenish hepatic glutathione level of mouse with cysteine derivatives.
Topics: Acetylcysteine; Aging; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Cystine; Female; Glutathione; Glutathione Disulfide; Liver; Male; Maleates; Mice; Rats; Rats, Inbred F344; Species Specificity | 1996 |
Expression of inducible nitric oxide synthase in endotoxemic rat hepatocytes is dependent on the cellular glutathione status.
Topics: Acetylcysteine; Animals; Binding Sites; Blotting, Western; Endotoxemia; Gene Expression; Glutathione; Immunohistochemistry; Kupffer Cells; Liver; Male; Maleates; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 1999 |
Glutathione modulates lipid composition of human colon derived HT-29 cells.
Topics: Acetylcysteine; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cholesterol Esters; Colon; Diglycerides; Glutathione; HT29 Cells; Humans; Lipid Metabolism; Maleates; Sulfhydryl Compounds; Triglycerides | 1998 |
In budding yeast, reactive oxygen species induce both RAS-dependent and RAS-independent cell cycle-specific arrest.
Topics: Acetylcysteine; Cell Cycle; Cell Division; Cyclin-Dependent Kinases; Cyclins; DNA; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, ras; Glutathione; Interphase; Maleates; Oxidative Stress; Reactive Oxygen Species; Saccharomyces cerevisiae | 1999 |
Arecoline cytotoxicity on human oral mucosal fibroblasts related to cellular thiol and esterase activities.
Topics: Acetylcysteine; Antimetabolites; Areca; Arecoline; Atropine; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Esterases; Expectorants; Fibroblasts; Ganglionic Stimulants; Humans; Maleates; Mouth Mucosa; Muscarinic Antagonists; Plants, Medicinal; Sulfhydryl Compounds; Thiolester Hydrolases | 1999 |
Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Brain; Curcuma; Glutathione; Ketones; Liver; Male; Maleates; Plant Extracts; Rats; Rats, Inbred Strains; Vitamin E | 1999 |
Implication of free radicals and glutathione in the mechanism of cadmium-induced expression of stress proteins in the A549 human lung cell-line.
Topics: Acetylcysteine; Cadmium Chloride; Cell Division; Cell Line; Dose-Response Relationship, Drug; Free Radicals; Gene Expression; Glutathione; Heat-Shock Proteins; Humans; Lung; Maleates | 2000 |
Retinoblastoma protein dephosphorylation is an early event of cellular response to prooxidant conditions.
Topics: Acetylcysteine; Adenovirus E2 Proteins; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Glutathione; HL-60 Cells; Humans; Maleates; Oxidants; Oxidation-Reduction; Oxidative Stress; Phosphoprotein Phosphatases; Phosphorylation; Protein Binding; Reactive Oxygen Species; Retinoblastoma Protein; Time Factors | 2000 |
Heterogeneity of clara cell glutathione. A possible basis for differences in cellular responses to pulmonary cytotoxicants.
Topics: Acetylcysteine; Animals; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleus; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cytoplasm; Cytotoxins; Epithelial Cells; Fluorescent Dyes; Glutathione; Lung; Maleates; Microscopy, Fluorescence; Mitochondria; Naphthalenes | 2000 |
Glutathione oxidation and PTPase inhibition by hydrogen peroxide in Caco-2 cell monolayer.
Topics: Acetylcysteine; Antineoplastic Agents, Alkylating; Caco-2 Cells; Carmustine; Catalase; Cell Membrane Permeability; Chelating Agents; Deferoxamine; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Intestinal Mucosa; Intestines; Iron; Maleates; Oxidants; Oxidation-Reduction; Phenanthrolines; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Sulfhydryl Compounds; Superoxide Dismutase; Thiomalates; Tight Junctions; Vitamin A; Vitamin E | 2000 |
Cold-induced apoptosis in isolated rat hepatocytes: protective role of glutathione.
Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cold Temperature; Glutathione; Hepatocytes; Hypothermia; Lipid Peroxidation; Male; Maleates; Rats; Rats, Wistar; Reactive Oxygen Species; Rewarming | 2001 |
Zinc toxicity on neonatal cortical neurons: involvement of glutathione chelation.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Cell Death; Cells, Cultured; Chelating Agents; Coculture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Maleates; Neuroglia; Neurons; Pyrrolidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thiocarbamates; Zinc | 2003 |
Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes.
Topics: Acetaldehyde; Acetylcysteine; Animals; Anthracenes; Apoptosis; Blotting, Western; Butadienes; Buthionine Sulfoximine; Caspase 3; Caspases; Cell Nucleus; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ethanol; Genistein; Hepatocytes; Hydrogen Peroxide; Indoles; JNK Mitogen-Activated Protein Kinases; Male; Maleates; Maleimides; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors | 2005 |
Prenatal diet determines susceptibility to cardiac ischaemia-reperfusion injury following treatment with diethylmaleic acid and N-acetylcysteine.
Topics: Acetylcysteine; Animals; Diet, Protein-Restricted; Disease Models, Animal; Female; Glutathione; Heart; Hemodynamics; Maleates; Maternal Exposure; Myocardial Reperfusion Injury; Myocardium; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Rats; Ventricular Dysfunction, Left | 2008 |
Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Carrier Proteins; Embryo, Nonmammalian; Ferritins; Fullerenes; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione Transferase; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; Light; Maleates; Microarray Analysis; Models, Animal; Oxidative Stress; Pericardial Effusion; Time Factors; Zebrafish | 2008 |
Glutathione depletion upregulates P-glycoprotein expression at the blood-brain barrier in rats.
Topics: Acetylcysteine; Animals; ATP Binding Cassette Transporter, Subfamily B; Blood-Brain Barrier; Dose-Response Relationship, Drug; Evans Blue; Free Radical Scavengers; Glutathione; Indicators and Reagents; Male; Maleates; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; Up-Regulation | 2009 |
Cellular antioxidant levels influence muscle stem cell therapy.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Blotting, Western; Cell Differentiation; Cell Proliferation; Cell Survival; Cell- and Tissue-Based Therapy; Cells, Cultured; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Female; Male; Maleates; Mice; Mice, Inbred C57BL; Mice, SCID; Muscle, Skeletal; Myocardial Infarction; Platelet Endothelial Cell Adhesion Molecule-1; Stem Cells; Vascular Endothelial Growth Factor A | 2010 |
Structure-activity comparison of the cytotoxic properties of diethyl maleate and related molecules: identification of diethyl acetylenedicarboxylate as a thiol cross-linking agent.
Topics: Acetylcysteine; Alkynes; Catalytic Domain; Cell Line, Tumor; Cross-Linking Reagents; Glutathione Peroxidase; Humans; Maleates; Saccharomyces cerevisiae; Structure-Activity Relationship; Sulfhydryl Compounds | 2011 |
Effects of N-acetyl-L-cysteine on target sites of hydroxylated fullerene-induced cytotoxicity in isolated rat hepatocytes.
Topics: Acetylcysteine; Animals; Cells, Cultured; Cysteine; Fullerenes; Glutathione; Hepatocytes; Hydroxylation; Male; Maleates; Malondialdehyde; Membrane Potential, Mitochondrial; Protective Agents; Rats; Rats, Inbred F344; Reactive Oxygen Species; Sulfhydryl Compounds | 2014 |
Deferoxamine promotes osteoblastic differentiation in human periodontal ligament cells via the nuclear factor erythroid 2-related factor-mediated antioxidant signaling pathway.
Topics: Acetylcysteine; Antioxidant Response Elements; Buthionine Sulfoximine; Calcification, Physiologic; Calcium; Cell Differentiation; Cell Line; Deferoxamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Maleates; MAP Kinase Signaling System; NF-E2-Related Factor 2; NF-kappa B; Osteoblasts; Periodontal Ligament; Reactive Oxygen Species; RNA, Small Interfering; Siderophores; Signal Transduction; Vitamin E | 2014 |
GSH protects against oxidative stress and toxicity in VL-17A cells exposed to high glucose.
Topics: Acetylcysteine; Alcohol Dehydrogenase; Antimetabolites; Antioxidants; Apoptosis; Buthionine Sulfoximine; Cell Survival; Clone Cells; Cytochrome P-450 CYP2E1; Glucose; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Hyperglycemia; Lactoylglutathione Lyase; Maleates; Oxidative Stress; Reactive Oxygen Species; Recombinant Proteins; Ursodeoxycholic Acid | 2015 |
N-acetylcysteine stimulates protein synthesis in enterocytes independently of glutathione synthesis.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Line; Cell Proliferation; Cysteine; Enterocytes; Eukaryotic Initiation Factors; Glutathione; Maleates; Protein Biosynthesis; Real-Time Polymerase Chain Reaction; Sus scrofa; TOR Serine-Threonine Kinases | 2016 |
Opposite in vivo effects of agents that stimulate or inhibit the glutamate/cysteine exchanger system xc- on the inhibition of hippocampal LTP by Aß.
Topics: Acetylcysteine; Amino Acid Transport Systems, Acidic; Amyloid beta-Peptides; Animals; Catheters, Indwelling; Central Nervous System Agents; Excitatory Postsynaptic Potentials; Glutathione; Hippocampus; Long-Term Potentiation; Male; Maleates; Peptide Fragments; Rats, Wistar; Sulfasalazine; Tumor Necrosis Factor-alpha | 2016 |