acetylcysteine and dichloroacetic acid

acetylcysteine has been researched along with dichloroacetic acid in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Arnold, DL; De Stefano, N; Ford, B; Genge, A; Karpati, G; Matthews, PM1
Dekant, W; Friedewald, M; Lederer, E; Pähler, A; Parker, J; Völkel, W1
Krishna, S; Planche, T1
Dai, Y; Huang, G; Liu, J; Qin, W; Sheng, S; Wang, H; Xiong, X1
Chen, A; Chen, L; Chen, S; Dai, X; He, F; Huang, C; Jiang, Y; Li, S; Li, T; Lian, J; Sun, L; Xiang, L; Xiao, H; Yan, X; Yang, M; Zhang, Y1

Reviews

1 review(s) available for acetylcysteine and dichloroacetic acid

ArticleYear
Severe malaria: metabolic complications.
    Current molecular medicine, 2006, Volume: 6, Issue:2

    Topics: Acetylcysteine; Acidosis, Lactic; Antimalarials; Dichloroacetic Acid; Humans; Hypoglycemia; Malaria, Falciparum

2006

Trials

1 trial(s) available for acetylcysteine and dichloroacetic acid

ArticleYear
Short-term dichloroacetate treatment improves indices of cerebral metabolism in patients with mitochondrial disorders.
    Neurology, 1995, Volume: 45, Issue:6

    Topics: Acetylcysteine; Adenosine Diphosphate; Adolescent; Adult; Aged; Alanine; Brain; Child; Creatine; Cross-Over Studies; Dichloroacetic Acid; Double-Blind Method; Female; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondrial Myopathies; Placebos; Pyruvate Dehydrogenase Complex

1995

Other Studies

4 other study(ies) available for acetylcysteine and dichloroacetic acid

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Biotransformation of perchloroethene: dose-dependent excretion of trichloroacetic acid, dichloroacetic acid, and N-acetyl-S-(trichlorovinyl)-L-cysteine in rats and humans after inhalation.
    Toxicology and applied pharmacology, 1998, Volume: 153, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Animals; Biotransformation; Carcinogens; Dichloroacetic Acid; Environmental Pollutants; Female; Half-Life; Humans; Inhalation Exposure; Male; Middle Aged; Rats; Rats, Wistar; Solvents; Tetrachloroethylene; Trichloroacetic Acid

1998
Dichloroacetate enhances adriamycin-induced hepatoma cell toxicity in vitro and in vivo by increasing reactive oxygen species levels.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Acetylcysteine; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Doxorubicin; Humans; Liver Neoplasms; Male; Mice; Reactive Oxygen Species; Xenograft Model Antitumor Assays

2014
Dichloroacetate enhances the anti-tumor effect of sorafenib via modulating the ROS-JNK-Mcl-1 pathway in liver cancer cells.
    Experimental cell research, 2021, 09-01, Volume: 406, Issue:1

    Topics: Acetylcysteine; Animals; Anthracenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Dichloroacetic Acid; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; Liver Neoplasms; Male; MAP Kinase Kinase 4; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Sorafenib; Tumor Burden; Xenograft Model Antitumor Assays

2021