acetylcysteine and deoxyguanosine

acetylcysteine has been researched along with deoxyguanosine in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (9.68)18.2507
2000's22 (35.48)29.6817
2010's34 (54.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furukawa, F; Hasegawa, R; Inoue, T; Kurokawa, Y; Nishikawa, A; Sai-Kato, K; Toyokuni, S; Uchida, K; Umemura, T1
Bonassi, S; De Biase, A; Deeva, IB; Degan, P; Doronin, YK; Iaccarino, M; Korkina, LG; Oral, R; Pagano, G; Warnau, M1
Bagnasco, M; Camoirano, A; De Flora, S; Izzotti, A; Orlando, M1
Hamilton, JW; Liu, KJ; Wetterhahn, KE; Yuann, JM1
Kawanishi, S; Oikawa, S; Tada-Oikawa, S; Yamada, K; Yamashita, N1
Chen, CC; Chen, CL; Chi, CW; Liu, TY1
Chen, CL; Chi, CW; Liu, TY1
Chipman, JK; Parsons, JL1
Akai, H; Hamada, J; Hosokawa, M; Kobayashi, Y; Konishi, Y; Moriuchi, T; Nakae, D; Nakata, D; Okada, F; Shibata, T1
Kamiya, H; Murata-Kamiya, N1
Jankowska, B; Jankowski, A; Kowalczyk, E; Niedworok, J; Smigielski, J1
Masutani, H; Nakamura, H; Nishiyama, A; Ohira, A; Tanaka, T; Tanito, M; Yodoi, J1
Maccioni, RB; Muñoz, P; Núñez, MT; Núñez-Millacura, C; Tapia, V1
Ercal, N; Lutz, P; Matthews, RH; Neal, R1
Irie, K; Maru, Y; Muraki, T; Ohba, K; Uchida, Y; Yoshioka, T1
Ball, LM; Gold, A; Jayaraj, K; Powley, MW; Swenberg, JA1
Fischer, E; Reliene, R; Schiestl, RH1
Brauchle, MA; Caselmann, WH; Gehrke, R; Gruetzner, U; Hildt, E; Hofschneider, PH; Rabe, C; Reifenberg, K; Schlicht, HJ; Schmitz, V1
Barzilai, N; Berg, AH; Brownlee, M; Combs, TP; Du, X; Fantus, IG; Giacca, A; Hawkins, M; Iyengar, P; Lam, TK; Li, W; Lin, Y; Rajala, MW; Rhodes, CJ; Rollman, B; Scherer, PE1
Decordier, I; Hantson, P; Haufroid, V; Lison, D; Van Caenegem, O1
Cao, EH; Qin, JF; Zhang, Y1
Agapova, LS; Budanov, AV; Chumakov, PM; Ilyinskaya, GV; Kravchenko, JE; Sablina, AA1
Biswas, SK; de Faria, JB1
Pang, Q; Qiu, Y; Sejas, DP; Williams, DA; Zhang, X1
Hamada, Y; Hazaka, Y; Ichijo, H; Kani, S; Minami, Y; Nakayama, E; Onishi, N; Sougawa, N; Takeda, K; Umeda, T; Yoda, A1
Abboud, HE; Gorin, Y; Habib, SL; Simone, S; Velagapudi, C1
Chen, X; Gao, P; Guo, L; He, P; Niu, Q; Wang, A; Xia, T; Xu, B; Xu, Z1
Arnold, LL; Cohen, SM; Kakiuchi-Kiyota, S; Pennington, KL; Suzuki, S1
Ahmed, M; Girnun, GD; Goldberg, SN; Levchenko, T; Rahmanuddin, S; Schor-Bardach, R; Signoretti, S; Solazzo, SA; Spitz, DR; Torchilin, V; Yang, W1
Unger, EC1
Ahmed, RS; Ahmed, T; Banerjee, BD; Kar, R; Mustafa, MD; Pathak, R; Tripathi, AK1
Hayashi, H; Imaoka, M; Ishii, Y; Mitsumori, K; Morita, R; Shibutani, M; Shimamoto, K; Suzuki, K; Taniai, E1
Beach, DG; Gabryelski, W; Manderville, RA; Witham, AA1
Brun, P; Cardin, R; Castagliuolo, I; Cavazzana, R; Deligianni, V; Leonardi, A; Martines, E; Spagnolo, S; Tarricone, E; Valerio, AL; Venier, P; Vono, M; Zuin, M1
Linhart, I; Míčová, K1
Cui, J; Lian, H; Liu, J; Shen, H; Wang, J; Wang, Y; Wu, S; Xing, L; Yan, X; Zhang, X1
Chung, BH; Doh, KC; Hyoung, BJ; Lim, SW; Piao, SG; Yang, CW1
Liu, RP; Zhou, JH; Zhu, BL1
Du, H; Li, J; Li, XF; McGuigan, CF; Moe, B; Shen, S1
Chung, BH; Doh, KC; Heo, SB; Jin, L; Kang, SH; Li, C; Lim, SW; Piao, SG; Yang, CW1
Chen, PC; Chen, YC; Chien, KL; Lee, HL; Liao, CC; Lien, GW; Lin, CY; Lin, LY; Su, TC; Sung, FC; Wen, LL1
Kawanishi, S; Midorikawa, K; Murata, M1
Abd-Ellah, MF; Ahmad, SF; Attia, SM; Bakheet, SA; Hamada, FM1
Adcock, I; Bhavsar, P; Chang, Y; Chung, KF; Clarke, C; Li, F; Seiffert, JM; Wiegman, C; Zhang, J; Zhou, X; Zhu, J1
Dong, H; Hu, L; Li, L; Song, E; Song, Y; Xu, D1
Bai, Y; Chen, M; Geng, CY; Jiang, LP; Li, Q; Liu, XF; Sun, Q; Wang, D; Yang, G; Zhong, LF1
Liu, H; Shi, J; Zhu, B1
Jiang, S; Lai, LY; Li, L; Liu, ZJ; Xu, SY; Zhang, QG; Zhao, W1
Andreoli, R; Banda, I; Barbaro, M; Goldoni, M; Mutti, A; Petyx, M; Pigini, D; Poli, D; Protano, C; Riccelli, MG; Spatari, G; Vitali, M1
Chen, ML; Huang, LW; Huang, YF; Wang, PW; Wu, KY; Yang, W1
Cai, GY; Chen, XM; Huang, MJ; Li, P; Li, QP; Wang, N; Wang, R; Wei, RB; Yang, X1
Cheng, X; Cui, L; Feng, D; Huang, H; Jin, Y; Yan, T; Yang, Y1
Barbieri, A; Doria, D; Drago, I; Fracasso, ME; Lovreglio, P; Sabatini, L; Soleo, L; Violante, FS1
Barkes, B; Canono, B; Day, B; Gillespie, M; Hamzeh, N; Huang, J; Li, L; Maier, L1
Cevik, O; Devranoglu, B; Eken, M; Isik Kaygusuz, E; Oztekin, D; Sahin Ersoy, G; Tal, R1
Garner, JP; Lay, DC; Lossie, AC; Radcliffe, JS; Vieira, GLT1
Chung, MH; Hahm, KB; Han, YM; Jeong, M; Ko, KH; Kwon, CI; Park, JM1
Alfieri, V; Barbieri, S; Bonomi, A; Casella, M; Cavalca, V; Colombo, GI; D'Alessandra, Y; Dello Russo, A; Di Minno, A; Porro, B; Russo, E; Tondo, C; Tremoli, E; Turnu, L1
Chan, YC; Chang, HW; Haung, JW; Huang, HW; Shu, CW; Tang, JY; Wang, HR; Wu, YC1
Lee, HL; Lin, CY; Su, TC; Sung, FC1
Khan, MF; Ma, H; Wang, G; Wang, J1
Hayashi, N; Hiratsuka, A; Nishiyama, T; Ogura, K; Ohnuma, T; Yanagita, H1

Trials

1 trial(s) available for acetylcysteine and deoxyguanosine

ArticleYear
The effect of an oral anti-oxidant, N-Acetyl-cysteine, on inflammatory and oxidative markers in pulmonary sarcoidosis.
    Respiratory medicine, 2016, Volume: 112

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Administration, Oral; Adult; Aged; Antioxidants; Bronchoalveolar Lavage Fluid; Deoxyguanosine; DNA; Double-Blind Method; Female; Glutathione; Humans; Inflammation; Lipopolysaccharides; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Sarcoidosis, Pulmonary; Tumor Necrosis Factor-alpha

2016

Other Studies

61 other study(ies) available for acetylcysteine and deoxyguanosine

ArticleYear
Prevention by 2-mercaptoethane sulfonate and N-acetylcysteine of renal oxidative damage in rats treated with ferric nitrilotriacetate.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Aldehydes; Animals; Antioxidants; Carcinogens; Deoxyguanosine; DNA; DNA Damage; Ferric Compounds; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxidation; Male; Mesna; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances

1996
L-methionine induces stage-dependent changes of differentiation and oxidative activity in sea urchin embryogenesis.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Anserine; Antioxidants; Carnosine; Chromosome Aberrations; Deoxyguanosine; Embryo, Nonmammalian; Free Radical Scavengers; Germ Cells; Luminescent Measurements; Methionine; Mitosis; Reactive Oxygen Species; Sea Urchins; Stereoisomerism

1997
DNA fragmentation, DNA-protein crosslinks, postlabeled nucleotidic modifications, and 8-hydroxy-2'-deoxyguanosine in the lung but not in the liver of rats receiving intratracheal instillations of chromium(VI). Chemoprevention by oral N-acetylcysteine.
    Mutation research, 1998, May-25, Volume: 400, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Administration, Oral; Animals; Antimutagenic Agents; Chromates; Chromium; Deoxyguanosine; DNA; DNA Fragmentation; Intubation, Intratracheal; Liver; Lung; Male; Nucleotides; Phosphorus Radioisotopes; Proteins; Rats; Rats, Sprague-Dawley

1998
In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium-DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of osteogenic disorder shionogi rats following treatment with chromium(VI).
    Carcinogenesis, 1999, Volume: 20, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antimetabolites; Ascorbic Acid; Buthionine Sulfoximine; Chromium; Deoxyguanosine; DNA Adducts; Free Radical Scavengers; Glutathione; Ketones; Kidney; Liver; Oxidation-Reduction; Rats; Rats, Mutant Strains

1999
N-acetylcysteine, a cancer chemopreventive agent, causes oxidative damage to cellular and isolated DNA.
    Carcinogenesis, 1999, Volume: 20, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Biomarkers; Copper; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; HL-60 Cells; Humans; Sequence Analysis, DNA; Tumor Cells, Cultured

1999
Safrole-induced oxidative damage in the liver of Sprague-Dawley rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Alanine Transaminase; Animals; Antidotes; Antioxidants; Aspartate Aminotransferases; Carcinogens; Deferoxamine; Deoxyguanosine; DNA Adducts; DNA Damage; Lipid Peroxides; Liver; Male; Microsomes, Liver; Oxidative Stress; Rats; Rats, Sprague-Dawley; Safrole; Vitamin E

1999
Enhanced hydroxychavicol-induced cytotoxic effects in glutathione-depleted HepG2 cells.
    Cancer letters, 2000, Jul-03, Volume: 155, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Catalase; Cell Survival; Deoxyguanosine; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Electrons; Eugenol; Free Radical Scavengers; Glutathione; Humans; Liver Neoplasms; Mutagens; Oxidative Stress; Reactive Oxygen Species; Time Factors; Tumor Cells, Cultured

2000
The role of glutathione in DNA damage by potassium bromate in vitro.
    Mutagenesis, 2000, Volume: 15, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Bromates; Carcinogens; Cattle; Cell Line; Chlorates; Chromatography, High Pressure Liquid; Comet Assay; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Epithelial Cells; Free Radicals; Glutathione; Glutathione Disulfide; Humans; Iodates; Kidney; Leukocytes; Potassium Compounds; Rats; Sulfhydryl Compounds; Thymus Gland; Time Factors

2000
Increased oxidative DNA damage in mammary tumor cells by continuous epidermal growth factor stimulation.
    Journal of the National Cancer Institute, 2001, Feb-07, Volume: 93, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenocarcinoma; Animals; Antioxidants; Deoxyguanosine; Disease Progression; DNA Damage; Epidermal Growth Factor; Female; Free Radical Scavengers; Glutathione Peroxidase; Mammary Neoplasms, Experimental; Microscopy, Confocal; Oxidative Stress; Rats; Rats, Inbred SHR; Selenium; Tumor Cells, Cultured

2001
Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA.
    Nucleic acids research, 2001, Aug-15, Volume: 29, Issue:16

    Topics: Acetylcysteine; Base Sequence; Binding Sites; Cross-Linking Reagents; Deoxyguanosine; DNA; DNA Polymerase I; DNA Replication; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Lysine; Pyruvaldehyde; Reducing Agents; Substrate Specificity; Templates, Genetic

2001
[The effect of anthocyanins from Aronii melanocarpa and acetylcysteine on selected after-effects of lead acetate poisoning].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 12, Issue:69

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Anthocyanins; Deoxyguanosine; Fatty Acids, Unsaturated; Female; Isoflavones; Lead Poisoning; Lipid Peroxidation; Male; Organometallic Compounds; Oxidative Stress; Rats; Rats, Wistar

2002
Change of redox status and modulation by thiol replenishment in retinal photooxidative damage.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Blotting, Western; Cross-Linking Reagents; Deoxyguanosine; Electroretinography; Glutaredoxins; Glutathione; Light; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Proteins; Radiation Injuries, Experimental; Retina; Retinal Degeneration; Thioredoxins

2002
An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells.
    Journal of neurochemistry, 2002, Volume: 82, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Cell Line; Cell Survival; Cells, Cultured; Deoxyguanosine; DNA; DNA Damage; Feedback, Physiological; Iron; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Mice; Neuroblastoma; Neurons; Oxidative Stress; RNA-Binding Proteins; Time Factors

2002
Antioxidant role of N-acetyl cysteine isomers following high dose irradiation.
    Free radical biology & medicine, 2003, Mar-15, Volume: 34, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Catalase; Deoxyguanosine; Erythrocytes; Glutaredoxins; Glutathione; Glutathione Reductase; Isomerism; Lung; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidants; Oxidation-Reduction; Oxidoreductases; Protein Disulfide Reductase (Glutathione); Radiation Injuries, Experimental; Radiation-Protective Agents; Whole-Body Irradiation

2003
Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway.
    The Journal of biological chemistry, 2004, Feb-06, Volume: 279, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adipocytes; Aldehydes; Animals; Antioxidants; Buthionine Sulfoximine; Cells, Cultured; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Free Radical Scavengers; Glycation End Products, Advanced; Lipid Peroxidation; Male; NF-kappa B; Oxidative Stress; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred OLETF; Reactive Oxygen Species; RNA, Messenger; Up-Regulation

2004
1,N2-propanodeoxyguanosine adducts of the 1,3-butadiene metabolite, hydroxymethylvinyl ketone.
    Chemical research in toxicology, 2003, Volume: 16, Issue:11

    Topics: Acetylcysteine; Animals; Butadienes; Butanones; Carcinogens; Cattle; Deoxyguanosine; DNA; DNA Adducts; Forecasting; Humans

2003
Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice.
    Cancer research, 2004, Aug-01, Volume: 64, Issue:15

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Deoxyguanosine; Dietary Supplements; DNA Damage; DNA-Binding Proteins; Female; Free Radical Scavengers; Genomic Instability; Male; Mice; Mice, Knockout; Optic Nerve; Oxidative Stress; Pigment Epithelium of Eye; Protein Serine-Threonine Kinases; Sequence Deletion; Sulfhydryl Compounds; Tumor Suppressor Proteins

2004
Accumulation of 8-hydroxy-2'-deoxyguanosine adducts in HBx recombinant HepG2 cells and HBx transgenic mice.
    Digestion, 2004, Volume: 70, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Deoxyguanosine; DNA Adducts; DNA, Recombinant; Humans; Liver; Liver Neoplasms; Mice; Mice, Transgenic; Trans-Activators; Viral Regulatory and Accessory Proteins

2004
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.
    The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6

    Topics: 3T3-L1 Cells; 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenoviridae; Adipocytes; Animals; Blotting, Northern; Cell Differentiation; Deoxyguanosine; Diabetes Mellitus, Experimental; Dicarboxylic Acid Transporters; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glucose; Hyperglycemia; Immunoblotting; Inflammation; Insulin; Interleukin-6; Membrane Potentials; Mice; Mitochondria; Oxidative Stress; Oxygen; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Streptozocin; Time Factors; Transcription, Genetic; Up-Regulation

2005
Hexavalent chromium ingestion: biological markers of nephrotoxicity and genotoxicity.
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adolescent; Ascorbic Acid; beta 2-Microglobulin; Biomarkers; Charcoal; Chromium; Creatinine; Deoxyguanosine; DNA Damage; Female; Humans; Kidney Tubules, Proximal; Oxidation-Reduction; Poisoning; Potassium Dichromate; Retinol-Binding Proteins; Suicide, Attempted

2005
Up-regulation of telomere-binding TRF1, TRF2 related to reactive oxygen species induced by As(2)O(3) in MGC-803 cells.
    European journal of pharmacology, 2005, May-23, Volume: 516, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Deoxyguanosine; Flow Cytometry; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Microscopy, Atomic Force; Oxides; Protein Binding; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Telomere; Telomeric Repeat Binding Protein 1; Telomeric Repeat Binding Protein 2; Tumor Suppressor Protein p53; Up-Regulation

2005
The antioxidant function of the p53 tumor suppressor.
    Nature medicine, 2005, Volume: 11, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Deoxyguanosine; DNA Damage; DNA Primers; Gene Expression Regulation; Genetic Vectors; Genomic Instability; Humans; Karyotyping; Lentivirus; Mice; Models, Biological; Mutagenesis; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Spleen; Tumor Suppressor Protein p53

2005
Which comes first: renal inflammation or oxidative stress in spontaneously hypertensive rats?
    Free radical research, 2007, Volume: 41, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Age Factors; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; Disease Models, Animal; Disease Progression; DNA Damage; Glutathione; Hypertension; Kidney Cortex; Male; NADPH Oxidases; Nephritis; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Tyrosine

2007
Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence.
    Journal of cell science, 2007, May-01, Volume: 120, Issue:Pt 9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Aldehydes; Animals; Apoptosis; Bone Marrow Cells; Bone Marrow Transplantation; Cell Cycle; Cell Differentiation; Cell Proliferation; Cellular Senescence; Deoxyguanosine; DNA Damage; Fanconi Anemia; Fanconi Anemia Complementation Group A Protein; Hematopoietic Stem Cells; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phosphorylation; Reactive Oxygen Species; Spleen; Sulfotransferases; Tumor Necrosis Factor-alpha

2007
Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling.
    Genes to cells : devoted to molecular & cellular mechanisms, 2007, Volume: 12, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Cell Line; Checkpoint Kinase 1; Checkpoint Kinase 2; Deoxyguanosine; Diabetes Mellitus; Enzyme Activation; G2 Phase; Guanidines; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase Kinase 5; Mesangial Cells; Mitosis; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvaldehyde; RNA, Small Interfering; Signal Transduction

2007
Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase.
    Diabetes, 2008, Volume: 57, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Cells, Cultured; Deoxyguanosine; Diabetes Mellitus; Diabetes Mellitus, Type 1; DNA Damage; DNA Glycosylases; Glucose; Hydrogen Peroxide; Immunoblotting; Immunohistochemistry; Kidney; Mice; Oncogene Protein v-akt; Oxidative Stress; Phosphorylation; Rats; Reactive Oxygen Species; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2008
Influence of PCB153 on oxidative DNA damage and DNA repair-related gene expression induced by PBDE-47 in human neuroblastoma cells in vitro.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 107, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Cell Line, Tumor; Deoxyguanosine; DNA Breaks; DNA Damage; DNA Repair; DNA-Binding Proteins; Gene Expression; Halogenated Diphenyl Ethers; Humans; Neuroblastoma; Oxidative Stress; Polychlorinated Biphenyls; Reactive Oxygen Species; X-ray Repair Cross Complementing Protein 1

2009
Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium.
    Toxicology, 2009, Jun-30, Volume: 261, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetophenones; Acetylcysteine; Animals; Antioxidants; Arsenites; Ascorbic Acid; Cacodylic Acid; Carcinogens; Cell Line; Cell Proliferation; Cytoprotection; Deoxyguanosine; Diet; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hyperplasia; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred F344; Sodium Compounds; Urinary Bladder; Urothelium

2009
Liposomal doxorubicin increases radiofrequency ablation-induced tumor destruction by increasing cellular oxidative and nitrative stress and accelerating apoptotic pathways.
    Radiology, 2010, Volume: 255, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Aldehydes; Animals; Apoptosis; Caspase 3; Catheter Ablation; Combined Modality Therapy; Deoxyguanosine; DNA Damage; Doxorubicin; Female; Histones; HSP70 Heat-Shock Proteins; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Oxidative Stress; Rats; Rats, Inbred F344; Tyrosine

2010
Science to practice: will randomized prospective clinical trials be necessary for RF ablation of large liver tumors with liposomal doxorubicin?
    Radiology, 2010, Volume: 255, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenocarcinoma; Aldehydes; Animals; Antibiotics, Antineoplastic; Apoptosis; Caspase 3; Catheter Ablation; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxyguanosine; DNA Damage; Doxorubicin; Histones; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Oxidative Stress; Prospective Studies; Randomized Controlled Trials as Topic; Rats; Tyrosine

2010
Ameliorating effect of N-acetylcysteine and curcumin on pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells.
    Environmental monitoring and assessment, 2011, Volume: 179, Issue:1-4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Antioxidants; Curcumin; Deoxyguanosine; DNA Damage; Endosulfan; Environmental Pollutants; Humans; Leukocytes, Mononuclear; Lipid Peroxidation; Malathion; Malondialdehyde; Oxidative Stress; Pesticides; Phosphamidon

2011
Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats.
    The Journal of toxicological sciences, 2011, Volume: 36, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Alkylating Agents; Animals; Antioxidants; Carcinogens; Deoxyguanosine; Diethylnitrosamine; DNA Damage; Gene Expression Profiling; Hepatectomy; Indoles; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Oligonucleotide Array Sequence Analysis; Organ Size; Oxidative Stress; Rats; Rats, Inbred F344; Reactive Oxygen Species; Weight Gain

2011
Hydroxyl radical-induced oxidation of a phenolic C-linked 2'-deoxyguanosine adduct yields a reactive catechol.
    Chemical research in toxicology, 2012, Feb-20, Volume: 25, Issue:2

    Topics: Acetylcysteine; Catechols; Copper; Deoxyguanosine; DNA Adducts; Edetic Acid; Ferrous Compounds; Hydrogen Peroxide; Hydroxyl Radical; Phenols

2012
Disinfection of ocular cells and tissues by atmospheric-pressure cold plasma.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adult; Atmospheric Pressure; Cell Cycle; Cell Survival; Conjunctiva; Corneal Keratocytes; Deoxyguanosine; Disinfection; Exocytosis; Eye; Fibroblasts; Humans; Microbial Viability; Phosphatidylserines; Plasma Gases; Protein Biosynthesis; Reactive Oxygen Species; Respiratory Burst; Time Factors; Transcription, Genetic; Virus Inactivation

2012
Reactions of benzene oxide, a reactive metabolite of benzene, with model nucleophiles and DNA.
    Xenobiotica; the fate of foreign compounds in biological systems, 2012, Volume: 42, Issue:10

    Topics: Acetylcysteine; Adenosine Monophosphate; Animals; Benzene; Cattle; Cyclohexanes; Deoxyadenosines; Deoxyguanine Nucleotides; Deoxyguanosine; DNA; DNA Adducts; Solutions; Spectrometry, Mass, Electrospray Ionization; Temperature

2012
Ochratoxin A induces oxidative DNA damage and G1 phase arrest in human peripheral blood mononuclear cells in vitro.
    Toxicology letters, 2012, Jun-01, Volume: 211, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Antioxidants; Apoptosis; Cyclin D1; Cyclin-Dependent Kinase 4; Deoxyguanosine; DNA Damage; G1 Phase Cell Cycle Checkpoints; Glutathione; Humans; Leukocytes, Mononuclear; Ochratoxins; Oxidative Stress; Reactive Oxygen Species

2012
Chronic cyclosporine nephropathy is characterized by excessive autophagosome formation and decreased autophagic clearance.
    Transplantation, 2012, Aug-15, Volume: 94, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Autophagy; Caspase 3; Cyclosporine; Deoxyguanosine; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Kidney Diseases; Male; Mice; Microscopy, Electron; Microtubule-Associated Proteins; Oxidative Stress; Phagosomes; Pravastatin; Time Factors

2012
[Relationship of urinary ttMA, S-PMA and 8-OHdG in workers to low-level BTEX].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2012, Volume: 30, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adolescent; Adult; Deoxyguanosine; Female; Furans; Humans; Hydrocarbons, Aromatic; Male; Occupational Exposure; Young Adult

2012
Cytotoxicity and oxidative damage induced by halobenzoquinones to T24 bladder cancer cells.
    Environmental science & technology, 2013, Mar-19, Volume: 47, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Antioxidants; Benzoquinones; Cell Line, Tumor; Deoxyguanosine; Disinfectants; Drinking Water; Halogenation; Humans; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Urinary Bladder; Urinary Bladder Neoplasms

2013
Influence of N-acetylcysteine on Klotho expression and its signaling pathway in experimental model of chronic cyclosporine nephropathy in mice.
    Transplantation, 2013, Jul-27, Volume: 96, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Chronic Disease; Cyclosporine; Deoxyguanosine; Disease Models, Animal; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression; Glucuronidase; Immunosuppressive Agents; Kidney Diseases; Klotho Proteins; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Proto-Oncogene Proteins c-akt; Signal Transduction; Superoxide Dismutase

2013
Positive association between urinary levels of 8-hydroxydeoxyguanosine and the acrylamide metabolite N-acetyl-S-(propionamide)-cysteine in adolescents and young adults.
    Journal of hazardous materials, 2013, Oct-15, Volume: 261

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Acrylamide; Adolescent; Adult; Child; Deoxyguanosine; Environmental Monitoring; Female; Humans; Male; Taiwan; Young Adult

2013
Oxidative DNA damage and mammary cell proliferation by alcohol-derived salsolinol.
    Chemical research in toxicology, 2013, Oct-21, Volume: 26, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Cell Line; Cell Proliferation; Coordination Complexes; Deoxyguanosine; DNA Damage; ErbB Receptors; Estrogen Receptor alpha; Ethanol; Female; Humans; Hydrogen Peroxide; Iron; Isoquinolines; Mammary Glands, Human; MCF-7 Cells; Oxidative Stress; Quinazolines; Transition Elements; Tyrphostins

2013
Germ cell mutagenicity of topoisomerase I inhibitor topotecan detected in the male mouse-dominant lethal study.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antineoplastic Agents; Deoxyguanosine; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Male; Mice; Mutagenicity Tests; Mutagens; Pregnancy; Reactive Oxygen Species; Spermatozoa; Topoisomerase I Inhibitors; Topotecan

2013
Effects of N-acetylcysteine in ozone-induced chronic obstructive pulmonary disease model.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Apoptosis; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Deoxyguanosine; Disease Models, Animal; Emphysema; Expectorants; Gene Expression; Lung; Malondialdehyde; Mice; Ozone; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests

2013
Evaluation of N-acetyl-cysteine against tetrachlorobenzoquinone-induced genotoxicity and oxidative stress in HepG2 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 64

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Benzoquinones; Deoxyguanosine; Enzyme-Linked Immunosorbent Assay; Hep G2 Cells; Histones; Humans; Hydrocarbons, Chlorinated; Micronucleus Tests; Mutagens; Oxidative Stress; Phosphorylation; Reactive Oxygen Species

2014
The role of oxidative stress in citreoviridin-induced DNA damage in human liver-derived HepG2 cells.
    Environmental toxicology, 2015, Volume: 30, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Aurovertins; Deoxyguanosine; DNA Damage; Glutathione; Hep G2 Cells; Humans; Lysosomes; Membrane Potential, Mitochondrial; Mycotoxins; Oxidative Stress; Reactive Oxygen Species

2015
[Determination of urinary 8-hydroxy-2'-deoxyguanosine, trans, trans-muconic acid, and S-phenylmercapturic acid by liquid chromatography-mass spectrometry].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2014, Volume: 32, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Benzene; Chromatography, Liquid; Deoxyguanosine; Humans; Mass Spectrometry; Occupational Exposure; Sorbic Acid

2014
OGG1 Involvement in High Glucose-Mediated Enhancement of Bupivacaine-Induced Oxidative DNA Damage in SH-SY5Y Cells.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Bupivacaine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Deoxyguanosine; DNA Damage; DNA Glycosylases; Glucose; Humans; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction

2015
Urinary biomarkers of exposure and of oxidative damage in children exposed to low airborne concentrations of benzene.
    Environmental research, 2015, Volume: 142

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Air Pollutants; Benzene; Biomarkers; Child; Child, Preschool; Cotinine; Deoxyguanosine; DNA; DNA Damage; Environmental Monitoring; Female; Guanine; Guanosine; Humans; Male; Methyl Ethers; Oxidation-Reduction; Sicily

2015
Prenatal nonylphenol exposure, oxidative and nitrative stress, and birth outcomes: A cohort study in Taiwan.
    Environmental pollution (Barking, Essex : 1987), 2015, Volume: 207

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adult; Biomarkers; Birth Weight; Cohort Studies; Deoxyguanosine; Dinoprost; DNA Damage; Environmental Pollutants; Female; Gestational Age; Guanine; Humans; Infant, Newborn; Lipid Peroxidation; Male; Maternal Exposure; Oxidative Stress; Phenols; Pregnancy; Pregnancy Outcome; Taiwan

2015
Renal Protective Effect of Probucol in Rats with Contrast-Induced Nephropathy and its Underlying Mechanism.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Sep-26, Volume: 21

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Contrast Media; Creatinine; Deoxyguanosine; Disease Models, Animal; Immunohistochemistry; Kidney; Kidney Diseases; Male; Malondialdehyde; Nitrogen; Oxidative Stress; Probucol; Rats; Rats, Wistar; Superoxide Dismutase

2015
Ameliorative effects of N-acetylcysteine on fluoride-induced oxidative stress and DNA damage in male rats' testis.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2015, Volume: 792

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Body Weight; Catalase; Deoxyguanosine; DNA Damage; Electrodes; Fluorides; Immunohistochemistry; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Sperm Count; Spermatozoa; Testis; Testosterone

2015
DNA damage and repair capacity in workers exposed to low concentrations of benzene.
    Environmental and molecular mutagenesis, 2016, Volume: 57, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adult; Benzene; Biomarkers; Case-Control Studies; Comet Assay; Deoxyguanosine; DNA Damage; DNA Repair; Humans; Lymphocytes; Male; Middle Aged; Occupational Exposure; Smoking; Sorbic Acid

2016
N-acetylcysteine leads to greater ovarian protection than enoxaparin sodium in a rat ovarian torsion model.
    Reproductive biomedicine online, 2016, Volume: 33, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Anti-Mullerian Hormone; Antioxidants; Deoxyguanosine; Enoxaparin; Female; Glutathione; In Situ Nick-End Labeling; Malondialdehyde; Ovarian Diseases; Ovarian Follicle; Ovary; Oxidative Stress; Peroxidase; Pilot Projects; Rats; Rats, Wistar; Reproductive Techniques, Assisted; Superoxide Dismutase

2016
Preventing, treating, and predicting barbering: A fundamental role for biomarkers of oxidative stress in a mouse model of Trichotillomania.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Biomarkers; Deoxyguanosine; Disease Models, Animal; Grooming; Mice; Mice, Inbred C57BL; Oxidative Stress; Trichotillomania

2017
Synthetic 8-hydroxydeoxyguanosine inhibited metastasis of pancreatic cancer through concerted inhibitions of ERM and Rho-GTPase.
    Free radical biology & medicine, 2017, Volume: 110

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Claudin-1; Deoxyguanosine; DNA-Binding Proteins; Epithelial-Mesenchymal Transition; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Humans; Hyaluronan Receptors; Imidazoles; Lung Neoplasms; Matrix Metalloproteinases; Mice; Mice, Nude; NADPH Oxidases; Pancreatic Neoplasms; Pyrroles; rho-Associated Kinases; Signal Transduction; Transcription Factors; Vimentin; Xenograft Model Antitumor Assays; Zonula Occludens-1 Protein

2017
Does Fluoroscopy Induce DNA Oxidative Damage in Patients Undergoing Catheter Ablation?
    Antioxidants & redox signaling, 2018, 04-20, Volume: 28, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Aged; Catheter Ablation; Deoxyguanosine; DNA; DNA Damage; Female; Fluoroscopy; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress

2018
4β-Hydroxywithanolide E selectively induces oxidative DNA damage for selective killing of oral cancer cells.
    Environmental toxicology, 2018, Volume: 33, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Deoxyguanosine; DNA Breaks, Double-Stranded; DNA Damage; Free Radical Scavengers; Gingival Neoplasms; Humans; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Signal Transduction

2018
Investigating the association between urinary levels of acrylonitrile metabolite N-acetyl-S-(2-cyanoethyl)-L-cysteine and the oxidative stress product 8-hydroxydeoxyguanosine in adolescents and young adults.
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 239

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Acrylonitrile; Adolescent; Adult; Asian People; Biomarkers; Deoxyguanosine; Environmental Exposure; Female; Humans; Male; Oxidative Stress; Smoking; Young Adult

2018
Contribution of poly(ADP-ribose)polymerase-1 activation and apoptosis in trichloroethene-mediated autoimmunity.
    Toxicology and applied pharmacology, 2019, 01-01, Volume: 362

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antibodies, Antinuclear; Apoptosis; Autoimmunity; bcl-2-Associated X Protein; Deoxyguanosine; DNA Damage; Female; Liver; Mice, Knockout; Poly (ADP-Ribose) Polymerase-1; Proto-Oncogene Proteins c-bcl-2; Solvents; Trichloroethylene

2019
4-(Hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronide has the potential to form 2'-deoxyguanosine and N-acetylcysteine adducts.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:10

    Topics: Acetylcysteine; Animals; Carcinogens; Deoxyguanosine; DNA Adducts; Esterases; Glucuronides; Liver; Mice; Nitrosamines

2019