acetylcysteine and deferoxamine

acetylcysteine has been researched along with deferoxamine in 120 studies

Research

Studies (120)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.83)	18.7374
1990's	26 (21.67)	18.2507
2000's	48 (40.00)	29.6817
2010's	39 (32.50)	24.3611
2020's	6 (5.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Asano, K; Dodo, K; Imamura, R; Kuboki, E; Magarisawa, M; Nakao, S; Shimizu, T; Sodeoka, M; Suda, T; Takahashi, M; Tanaka, M; Terayama, N; Tokuhiro, T; Yotsumoto, S	1
D'Acunto, CW; Gonzalez, G; Hodoň, J; Kaňovský, P; Kazakova, A; Strnad, M; Urban, M	1
Davies, MJ; Newman, ES; Rice-Evans, CA; Turner, JJ	1
Farber, JL; Hoek, JB; Starke, PE	1
Blöhmer, A; Hänel, H; Heidemann, HT; Inselmann, G; Kottny, W; Nellessen, U	1
Collis, CS; Davies, MJ; Rice-Evans, C	1
Chambers, TJ; Fuller, K; Hall, TJ; Jeker, H; Schaeublin, M	1
Klee, S; Nürnberger, MC; Ungemach, FR	1
Proudfoot, AT	1
Faux, SP; Howden, PJ	1
Farinelli, SE; Greene, LA; Park, DS; Stefanis, L; Yan, CY	1
Baraban, JM; Lee, PJ; Ratan, RR	1
Bowden, CA; Krenzelok, EP	1
Bowie, A; O'Neill, LA	1
Galle, J; Galle, PR; Grambihler, A; Hack, V; Hug, H; Krammer, PH; Strand, S; Stremmel, W	1
Higuchi, Y; Matsukawa, S	1
Hansen, TW; Knisely, AS; Kocoshis, SA; Reyes, J; Rosh, J; Sigurdsson, L	1
Czyzyk-Krzeska, MF; Kroll, SL	1
Cheng, CC; Chiu, JJ; Hsieh, HJ; Wang, DL; Wu, ST; Wung, BS	1
Boussa, N; Dutertre-Catella, H; Ernouf, D; Legras, A	1
Fernandez, PA; Martinou, I; Martinou, JC; Missotten, M; Sadoul, R	1
Devlin, RB; Quay, JL; Reed, W; Samet, J	1
Danaee, H; Goldsmith, CA; Imrich, A; Kobzik, L; Ning, YY	1
Fukuchi, K; Gomi, K; Nakamaki, T; Tomoyasu, S; Tsuruoka, N	1
Bucci, TJ; Hinson, JA; Kusewitt, DF; Pumford, NR; Schnellmann, JG	1
Fukuchi, K; Gomi, K; Maruyama, H; Takagi, Y	1
Chen, CC; Chen, CL; Chi, CW; Liu, TY	1
Hashimoto, M; Hsu, LJ; Masliah, E; Takeda, A; Takenouchi, T	1
Harris, DC; Rangan, GK; Tay, YC; Wang, Y	1
Defraigne, JO; Detry, O; Franssen, C; Limet, R; Meurisse, M; Pincemail, J	1
Alvarez, AM; Andrés, D; Cascales, M; Díez-Fernández, C; Zaragoza, A	2
Auer, M; Leib, SL; Leppert, D; Pfister, LA; Täuber, MG	1
Diamond, E; Drigues, N; Klein, I; Lischinsky, S; Nagler, R; Reznick, AZ	1
Baker, RD; Baker, SS; Gupta, A; Li, L; Rao, RK	1
Lai, CC; Ryter, SW; Si, M; Su, CY	1
Bauer, I; Bauer, M; Pannen, BH; Paxian, M; Rensing, H; Rickauer, A; Schmeck, J; Schönhofen, S	1
Delogu, MR; Desole, MS; Esposito, G; Miele, E; Miele, M; Migheli, R; Rocchitta, G; Serra, PA	1
Castranova, V; Costa, M; Huang, C; Ju, G; Leonard, SS; Li, J; Shi, X; Vallyathan, V; Zhang, Z	1
Oliveira, DB; Turner, DR; Wu, Z	1
Angelos, MG; Clanton, TL; Klawitter, PF; Murray, HN	1
Backlund, PS; Bourdon, E; Drake, SK; Levine, RL; Rouault, TA; Wehr, NB; Yergey, AL	1
Abdel-Naim, AB; Mohamadin, AM	1
Caltagirone, A; Chahine, D; Fillebeen, C; Pantopoulos, K; Segal, P	1
Balaspiri, L; Bogdanovic, N; Karelson, E; Land, T; Langel, U; Mahlapuu, R; Saar, K; Soomets, U; Viht, K; Zilmer, M	1
Hatakeyama, M; Imaizumi, T; Kimura, D; Kumagai, M; Satoh, K; Tamo, W; Yamashita, K; Yoshida, H	1
Andrades, ME; Dal-Pizzol, F; Menna-Barreto, S; Moreira, JC; Reinke, A; Ritter, C	1
Crouser, ED	1
Becker, HH; Dopp, E; Lohani, M; Poser, I; Rahman, Q; Schiffmann, D; Weiss, DG; Yadav, S	1
Crommelin, DJ; Danhof, M; de Boer, AG; Visser, CC; Voorwinden, LH	1
Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J	1
Agani, FH; Gong, Y	1
Le, W; Pan, T; Qu, S; Wang, X; Xie, W; Zhang, X	1
Bockmühl, U; Fuchs, J; Gross, J; Jahnke, V; Kietzmann, T; Machulik, A	1
Chakrabarti, SK; Lemieux, N; M'Bemba-Meka, P	2
Dal-Pizzol, F; F Moreira, JC; Luiz Streck, E; Pinho, RA; Silva, LA; Silveira, PC	1
Andrades, M; da Cunha, AA; Dal-Pizzol, F; Echer, IC; Lucchiari, N; Menna-Barreto, S; Moreira, JC; Reinke, A; Ritter, C; Rocha, J; Streck, EL	1
Cross, CE; Halliwell, B; van Asbeck, BS	1
Ameri, K; Culmsee, C; Davis, RJ; Denko, N; Hai, T; Hammond, EM; Harris, AL; Katschinski, DM; Raida, M; Wagner, E; Wenger, RH	1
Howarth, ES; Venkat-Raman, N; Venkata-Krishnan, RV	1
Arrigo, AP; Currie, RW; Firdaus, WJ; Giuliano, P; Kretz-Remy, C; Wyttenbach, A	1
de Groot, H; Klempt, S; Rauen, U	1
Akatov, VS; Faskhutdinova, AA; Kudriavtsev, AA; Solov'ev, VV; Solov'eva, ME	1
Bardini, KC; Benetton, CA; Cardoso, VH; Dal-Pizzol, F; Damiani, CR; Di Giunta, G; Pinho, RA; Stoffel, C; Streck, EL	1
Andrades, M; Bernard, EA; Dal-Pizzol, F; de Souza, LF; Moreira, JC; Pens Gelain, D; Ritter, C	1
Blomqvist, G; Dahl, A; Gudmundsson, A; Gustafsson, M; Lindbom, J; Ljungman, AG; Swietlicki, E	1
Barichello, T; Constantino, L; Dal-Pizzol, F; Machado, RA; Martins, MR; Petronilho, F; Quevedo, J; Réus, GZ; Ritter, C; Valvassori, SS	1
Dal Pizzol, F; Pinho, RA; Rocha, LG; Silva, LA; Silveira, PC; Soares, FS; Streck, EL; Teixeira, KC; Valença, SS	1
Aguiar, AS; da Rocha, LG; Pinho, RA; Silveira, PC; Soares, FS; Tuon, T	1
Amer, J; Fibach, E; Ghoti, H; Rachmilewitz, E; Winder, A	1
Arai, T; Hirota, K; Kodaki, T; Makino, K; Miyoshi, T; Mori, H; Sasada, M; Sommani, P; Tsunemine, H; Yamashita, K	1
Burigo, M; Constantino, L; Dal-Pizzol, F; Di-Pietro, PB; Dias, ML; Machado, RA; Scaini, G; Streck, EL	1
Boeck, CR; Dal-Pizzol, F; Kapczinski, F; Oliveira, VB; Petronilho, FC; Quevedo, J; Réus, GZ; Steckert, AV; Valvassori, SS	1
Faurschou, A; Gniadecki, R	1
Constantino, L; Dal-Pizzol, F; de Souza, B; Fraga, CM; Martins, MR; Petronilho, F; Reinke, A; Ritter, C	1
Aydin, A; Bulucu, F; Inal, V; Karadurmus, N; Kenar, L; Koc, B; Ocal, R; Oktenli, C; Sahin, M; Yaman, H; Yamanel, L	1
Andrades, M; Dal-Pizzol, F; de Oliveira, MR; Fonseca Moreira, JC; Ritter, C; Streck, EL	1
Cassol, OJ; Dal-Pizzol, F; Ferreira, GK; Gonçalves, CL; Petronilho, FC; Rezin, GT; Roesler, R; Scaini, G; Schwartsmann, G; Streck, EL	1
Barbosa, PR; Cardoso, MR; Dal-Pizzol, F; Daufenbach, JF; Gonçalves, CL; Machado, RA; Rezin, GT; Roza, CA; Scaini, G; Schuck, PF; Streck, EL	1
Carvalho-Silva, M; Daufenbach, JF; Ferreira, GK; Gonçalves, CL; Jeremias, GC; Jeremias, IC; Panatto, JP; Ramos, AC; Rezin, GT; Rochi, N; Scaini, G; Streck, EL	1
Altunhan, H; Annagür, A; Örs, R; Yüksekkaya, HA	1
Aidasani, D; Reid, DL; Skiles, GL; Subramanian, R; Tam, J	1
Caruana, M; Giese, A; Hillmer, A; Högen, T; Levin, J; Vassallo, N	1
Biff, D; Dal-Pizzol, F; Felisberto, F; Fraga, CM; Petronilho, F; Ritter, C; Tomasi, CD; Topanotti, MF; Vuolo, F	1
Comim, CM; Dominguini, D; Ferreira, GC; Jeremias, IC; Mina, F; Morais, MO; Pescador, B; Quevedo, J; Scaini, G; Schuck, PF; Streck, EL; Teodorak, BP	1
Barichello, T; Comim, CM; Dal-Pizzol, F; Generoso, JS; Michelon, CM; Mina, F; Otaran, P; Quevedo, J; Santos, AL; Savi, GD; Steckert, AV	1
Abelaira, HM; Arent, CO; Dal-Pizzol, F; Mina, F; Quevedo, J; Réus, GZ; Ribeiro, KF; Steckert, AV	1
Benoit-Vical, F; Berry, A; Gales, A; Huyghe, E; Njomnang Soh, P; Pipy, B; Witkowski, B	1
Bogo, MR; Comim, CM; Ferreira, GC; Gelain, DP; Moreira, JC; Oliveira, GM; Pasquali, MA; Quevedo, J; Scaini, G; Schuck, PF; Streck, EL	1
Boesch-Saadatmandi, C; Ciesla, M; Dulak, J; Jozkowicz, A; Kozakowska, M; Loboda, A; Rimbach, G; Stachurska, A; Wolffram, S	1
Brodsky, SV; Hebert, LA; Nadasdy, G; Nadasdy, T; Ozcan, A; Qamri, Z; Rovin, BH; Satoskar, AA; Ware, K	1
Chang, SW; Chung, JH; Kim, EC; Kim, YS; Lee, YM; Noh, K	1
Evans, TW; Griffiths, MJ; Mumby, S; Quinlan, GJ; Ramakrishnan, L	1
Ibrahim, MA; Isah, MB	1
Gutierrez, E; Jansson, PJ; Richardson, DR	1
Bollineli, RC; Marques, MJ; Minatel, E; Mizobuti, DS; Moraes, LH; Silveira, Ldos R	1
Jiménez-Vélez, BD; Ortiz-Martínez, MG; Rodríguez-Cotto, RI	1
Amboni, RT; Arent, CO; Bianchini, G; Dal-Pont, GC; Lopes-Borges, J; Quevedo, J; Resende, WR; Steckert, AV; Valvassori, SS	1
Andrades, M; Biolo, A; Clausell, N; Cohen, C; Dal-Pizzol, F; Lopes, A; Martinelli, N; Olsen, V; Phaelante, A; Rohde, LE; Tobar, SA	1
Abelaira, HM; Bruchchen, L; Carlessi, AS; Ceretta, LB; Dos Santos, MA; Florentino, D; Matias, BI; Petronilho, F; Quevedo, J; Réus, GZ; Titus, SE; Vieira, A; Zugno, AI	1
Abelaira, HM; Arent, CO; Bernardini Dos Santos, MA; Bruchchen, L; Carvalho, AF; Dal-Pizzol, F; Ignácio, ZM; Maciel, AL; Matias, BI; Michels, M; Quevedo, J; Réus, GZ; Zugno, AI	1
Arkadopoulos, NF; Dimas, C; Karmaniolou, II; Kondi-Pafiti, AI; Lolis, ED; Mylonas, AI; Orfanos, NF; Papalois, AE; Smyrniotis, VE; Stergiou, IP	1
Chattipakorn, N; Chattipakorn, SC; Krintratun, W; Sripetchwandee, J; Wongjaikam, S	1
Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Khamseekaew, J; Kumfu, S; Srichairatanakool, S; Sripetchwandee, J; Wongjaikam, S	1
Arkadopoulos, N; Karmaniolou, I; Mani, A; Mylonas, A; Nomikos, T; Orfanos, N; Pafiti, A; Papalois, A; Smyrniotis, V; Staikou, C; Theodoraki, K	1
Dal-Pizzol, F; Damasio, DC; Fraga, CM; Ritter, C; Tomasi, CD; Vuolo, F	1
Carvalho-Silva, M; De Prá, SD; Ferreira, GC; Gomes, LM; Rebelo, J; Scaini, G; Schuck, PF; Streck, EL; Teixeira, LJ; Teodorak, BP; Zeni, N	1
Adedoyin, O; Agarwal, A; Boddu, R; Bolisetty, S; George, JF; Lever, JM; Traylor, A	1
Kasukabe, T; Kumakura, S; Yamaguchi, Y	1
Bogo, MR; Carvalho-Silva, M; de Moura, AB; Deroza, PFP; Ferreira, GC; Gomes, LM; Gomes, ML; Kist, LW; Malgarin, F; Quevedo, J; Réus, GZ; Rico, EP; Scaini, G; Schuck, PF; Streck, EL; Zugno, AI	1
He, M; Ichinose, T; Nishikawa, M; Shibamoto, T; Sun, G; Yoshida, S	1
Amiot, BP; Chen, HS; Joo, DJ; Li, Y; Nyberg, SL; Rinaldo, P; Shaheen, M	1
Constantino, L; Dal-Pizzol, F; Damásio, D; Fraga, C; Gonçalves, RC; Michels, M; Ritter, C	1
Araújo Montoya, BO; Brum, PO; Campos Soares, M; Carazza Kessler, FG; Castro-Faria-Neto, HC; Dal-Pizzol, F; Fonseca Moreira, JC; Gasparotto, J; Gelain, DP; Góes Valente, WC; Ong, LK; Panzenhagen, AC; Peixoto, DO; Reis, PA; Schirato, GV; Senger, MR; Silva, FP; Telles de Sá Moreira, E	1
Aguayo, R; Gajardo, A; Lillo-Moya, J; Panieri, E; Prieto, JC; Puentes, Á; Ramos, C; Rodrigo, R; Rojas-Solé, C; Saso, L	1
Dong, Y; Du, GF; Fan, X; Le, YJ; Yang, XY; Yin, A	1
Bao, Y; Chang, X; Dong, S; Duan, X; Li, Y; Lin, J; Shan, H; Tan, Y; Zhang, H	1

Reviews

5 review(s) available for acetylcysteine and deferoxamine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antidotes: benefits and risks. Toxicology letters, 1995, Volume: 82-83 Topics: Acetylcysteine; Animals; Antidotes; Deferoxamine; Flumazenil; Humans; Naloxone	1995
Clinical applications of commonly used contemporary antidotes. A US perspective. Drug safety, 1997, Volume: 16, Issue:1 Topics: Acetylcysteine; Antidotes; Antivenins; Atropine; Deferoxamine; Flumazenil; Humans; Hydroxocobalamin; Naloxone; Physostigmine; Poisoning; Succimer	1997
The role of antioxidants treatment on the pathogenesis of malarial infections: a review. Parasitology research, 2014, Volume: 113, Issue:3 Topics: Acetylcysteine; Antimalarials; Antioxidants; Ascorbic Acid; Deferoxamine; Folic Acid; Humans; Malaria; Oxidative Stress; Plasmodium; Vitamin E	2014
Joint Cardioprotective Effect of Vitamin C and Other Antioxidants against Reperfusion Injury in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention. Molecules (Basel, Switzerland), 2021, Sep-21, Volume: 26, Issue:18 Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Male; Myocardial Infarction; Oxidative Stress; Percutaneous Coronary Intervention; Polyphenols; Protective Agents; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Stroke Volume; Tocopherols; Ventricular Function, Left	2021

Trials

2 trial(s) available for acetylcysteine and deferoxamine

Article	Year
The effects of N-acetylcysteine and deferoxamine on plasma cytokine and oxidative damage parameters in critically ill patients with prolonged hypotension: a randomized controlled trial. Journal of clinical pharmacology, 2012, Volume: 52, Issue:9 Topics: Acetylcysteine; Acute Kidney Injury; Adult; Aged; Antioxidants; Critical Illness; Deferoxamine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypotension; Interleukin-6; Male; Middle Aged; Nitrites; Oxidative Stress; Siderophores	2012
N-acetylcysteine plus deferoxamine for patients with prolonged hypotension does not decrease acute kidney injury incidence: a double blind, randomized, placebo-controlled trial. Critical care (London, England), 2016, 10-17, Volume: 20, Issue:1 Topics: Acetylcysteine; Acute Kidney Injury; Adult; Aged; Critical Illness; Deferoxamine; Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Hypotension; Incidence; Intensive Care Units; Male; Middle Aged	2016

Article

Year

The effects of N-acetylcysteine and deferoxamine on plasma cytokine and oxidative damage parameters in critically ill patients with prolonged hypotension: a randomized controlled trial.

Journal of clinical pharmacology, 2012, Volume: 52, Issue:9

Topics: Acetylcysteine; Acute Kidney Injury; Adult; Aged; Antioxidants; Critical Illness; Deferoxamine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypotension; Interleukin-6; Male; Middle Aged; Nitrites; Oxidative Stress; Siderophores

2012

N-acetylcysteine plus deferoxamine for patients with prolonged hypotension does not decrease acute kidney injury incidence: a double blind, randomized, placebo-controlled trial.

Critical care (London, England), 2016, 10-17, Volume: 20, Issue:1

Topics: Acetylcysteine; Acute Kidney Injury; Adult; Aged; Critical Illness; Deferoxamine; Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Hypotension; Incidence; Intensive Care Units; Male; Middle Aged

2016

Other Studies

113 other study(ies) available for acetylcysteine and deferoxamine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a Water-Soluble Indolylmaleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosis. ACS medicinal chemistry letters, 2019, Sep-12, Volume: 10, Issue:9 Topics:	2019
Novel pentacyclic triterpenes exhibiting strong neuroprotective activity in SH-SY5Y cells in salsolinol- and glutamate-induced neurodegeneration models. European journal of medicinal chemistry, 2021, Mar-05, Volume: 213 Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Isoquinolines; Membrane Potential, Mitochondrial; Models, Biological; Molecular Structure; Neuroprotective Agents; Oxidative Stress; Structure-Activity Relationship; Triazoles; Triterpenes	2021
The formation of free radicals by cardiac myocytes under oxidative stress and the effects of electron-donating drugs. The Biochemical journal, 1991, Aug-01, Volume: 277 ( Pt 3) Topics: Acetylcysteine; Animals; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; In Vitro Techniques; Lipid Peroxides; Metmyoglobin; Myocardium; Oxidation-Reduction; Peroxides; Rabbits; Reperfusion Injury; Tiopronin	1991
Calcium-dependent and calcium-independent mechanisms of irreversible cell injury in cultured hepatocytes. The Journal of biological chemistry, 1986, Mar-05, Volume: 261, Issue:7 Topics: Acetylcysteine; Animals; Calcium; Cell Survival; Cells, Cultured; Deferoxamine; Dithiothreitol; Glucose Oxidase; Glutathione; Homeostasis; Hydrogen Peroxide; Iron; Liver; Male; NADP; Onium Compounds; Phosphorylase a; Rats; Rats, Inbred Strains; Trityl Compounds; Vitamin K	1986
Modification of cisplatin-induced renal p-aminohippurate uptake alteration and lipid peroxidation by thiols, Ginkgo biloba extract, deferoxamine and torbafylline. Nephron, 1995, Volume: 70, Issue:4 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cisplatin; Deferoxamine; Glutathione; In Vitro Techniques; Kidney Cortex; Lipid Peroxidation; Male; p-Aminohippuric Acid; Pentoxifylline; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds	1995
Comparison of N-methyl hexanoylhydroxamic acid, a novel antioxidant, with desferrioxamine and N-acetyl cysteine against reperfusion-induced dysfunctions in isolated rat heart. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Cardiovascular Agents; Deferoxamine; Heart; Heart Rate; Hydroxamic Acids; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Perfusion; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Pressure	1993
The role of reactive oxygen intermediates in osteoclastic bone resorption. Biochemical and biophysical research communications, 1995, Feb-06, Volume: 207, Issue:1 Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Bone Resorption; Cell Survival; Cells, Cultured; Deferoxamine; Free Radical Scavengers; NF-kappa B; Osteoclasts; Pyrrolidines; Rats; Reactive Oxygen Species; Thiocarbamates	1995
The consequences of nitrofurantoin-induced oxidative stress in isolated rat hepatocytes: evaluation of pathobiochemical alterations. Chemico-biological interactions, 1994, Volume: 93, Issue:2 Topics: Acetylcysteine; Animals; Carmustine; Deferoxamine; Dithiothreitol; Glutathione; Glutathione Reductase; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Nitrofurantoin; Oxidation-Reduction; Rats; Rats, Wistar; Stress, Physiological	1994
Fibre-induced lipid peroxidation leads to DNA adduct formation in Salmonella typhimurium TA104 and rat lung fibroblasts. Carcinogenesis, 1996, Volume: 17, Issue:3 Topics: Acetylcysteine; Animals; Antidotes; Asbestos, Crocidolite; Asbestos, Serpentine; Buthionine Sulfoximine; Carcinogens; Deferoxamine; DNA; DNA Adducts; Enzyme Inhibitors; Ferrozine; Fibroblasts; Glass; Glutathione; Lipid Peroxidation; Lung; Malondialdehyde; Methionine Sulfoximine; Mineral Fibers; Rats; Salmonella typhimurium; Thiobarbituric Acid Reactive Substances	1996
Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells. The Journal of biological chemistry, 1996, Sep-06, Volume: 271, Issue:36 Topics: Acetylcysteine; Animals; Apoptosis; Apoptosis Regulatory Proteins; Aurintricarboxylic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Caspase 1; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cysteine Endopeptidases; Dactinomycin; Deferoxamine; Enzyme Activation; Humans; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Nerve Growth Factors; PC12 Cells; Rats; RNA; Serpins; Viral Proteins	1996
Serum deprivation inhibits glutathione depletion-induced death in embryonic cortical neurons: evidence against oxidative stress as a final common mediator of neuronal apoptosis. Neurochemistry international, 1996, Volume: 29, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Butylated Hydroxyanisole; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; Cystine; Deferoxamine; Glutathione; Insulin; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley	1996
Studies into the mechanism of NF kappa B activation by IL1, TNF and H2O2 in primary and transformed endothelial cells. Biochemical Society transactions, 1997, Volume: 25, Issue:1 Topics: Acetylcysteine; Allopurinol; Cell Line, Transformed; Cells, Cultured; Cyclic N-Oxides; Deferoxamine; DNA-Binding Proteins; Endothelium, Vascular; Humans; Hydrogen Peroxide; I-kappa B Proteins; Interleukin-1; Kinetics; NF-kappa B; NF-KappaB Inhibitor alpha; Pyrrolidines; Thiocarbamates; Tumor Necrosis Factor-alpha; Umbilical Veins	1997
Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells. The Journal of biological chemistry, 1997, Nov-07, Volume: 272, Issue:45 Topics: Acetylcysteine; Actins; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antioxidants; Apoptosis; Bleomycin; Carcinoma, Hepatocellular; Deferoxamine; Fas Ligand Protein; fas Receptor; Glutathione; Humans; Hydrogen Peroxide; Ligands; Membrane Glycoproteins; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation	1997
Active oxygen-mediated chromosomal 1-2 Mbp giant DNA fragmentation into internucleosomal DNA fragmentation in apoptosis of glioma cells induced by glutamate. Free radical biology & medicine, 1998, Volume: 24, Issue:3 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Catalase; Chromosomes; Deferoxamine; DNA Fragmentation; Free Radical Scavengers; Glioma; Glutamic Acid; Glutathione; Hydrogen Peroxide; Iron Chelating Agents; Oxidation-Reduction; Oxygen; Phenanthrolines; Rats; Tumor Cells, Cultured	1998
Neonatal hemochromatosis: outcomes of pharmacologic and surgical therapies. Journal of pediatric gastroenterology and nutrition, 1998, Volume: 26, Issue:1 Topics: Acetylcysteine; Alprostadil; Antioxidants; Chelating Agents; Deferoxamine; Hemochromatosis; Humans; Infant, Newborn; Liver Transplantation; Retrospective Studies; Selenium; Treatment Outcome; Vitamin E	1998
Role of H2O2 and heme-containing O2 sensors in hypoxic regulation of tyrosine hydroxylase gene expression. The American journal of physiology, 1998, Volume: 274, Issue:1 Topics: Acetylcysteine; Actins; Amitrole; Animals; Antioxidants; Biosensing Techniques; Catalase; Cell Hypoxia; Deferoxamine; Gene Expression Regulation, Enzymologic; Heme; Hydrogen Peroxide; Kinetics; Oxygen; PC12 Cells; Rats; RNA, Messenger; Tiopronin; Transcription, Genetic; Tyrosine 3-Monooxygenase	1998
Increase of reactive oxygen species (ROS) in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression. Journal of cellular physiology, 1998, Volume: 175, Issue:2 Topics: Acetylcysteine; Amitrole; Antioxidants; Catalase; Chelating Agents; Deferoxamine; Endothelium, Vascular; Fluoresceins; Free Radical Scavengers; Gene Expression Regulation; Genes, fos; Hemodynamics; Humans; Hydrogen Peroxide; Reactive Oxygen Species; RNA; Thiourea; Umbilical Cord	1998
Acute paraquat poisoning: increased toxicity in one case with high alcohol intake. Human & experimental toxicology, 1998, Volume: 17, Issue:3 Topics: Acetylcysteine; Alcohol Drinking; Antidotes; Deferoxamine; Diuretics, Osmotic; Ethanol; Excipients; Expectorants; Fatal Outcome; Herbicides; Humans; Male; Mannitol; Middle Aged; Paraquat; Polyethylene Glycols	1998
Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons. Neuroreport, 1998, Jan-05, Volume: 9, Issue:1 Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Deferoxamine; Membrane Proteins; Nerve Tissue Proteins; Neurons; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Superior Cervical Ganglion	1998
Air pollution particles induce IL-6 gene expression in human airway epithelial cells via NF-kappaB activation. American journal of respiratory cell and molecular biology, 1998, Volume: 19, Issue:1 Topics: Acetylcysteine; Air Pollutants; Bronchi; Carbon; Cell Line; Coal Ash; Deferoxamine; DNA; Epithelial Cells; Free Radical Scavengers; Fuel Oils; Gene Expression Regulation; Humans; Interleukin-6; Metals; NF-kappa B; Particulate Matter; Promoter Regions, Genetic; RNA, Messenger; Transfection	1998
Analysis of air pollution particulate-mediated oxidant stress in alveolar macrophages. Journal of toxicology and environmental health. Part A, 1998, Aug-07, Volume: 54, Issue:7 Topics: Acetylcysteine; Air Pollutants; Animals; Cell Line; Chelating Agents; Chemokines, CC; Cricetinae; Cytokines; Deferoxamine; Environmental Exposure; Fluoresceins; Free Radical Scavengers; Macrophage Inflammatory Proteins; Macrophages, Alveolar; Oxidative Stress; Particle Size; Reactive Oxygen Species; RNA; Tumor Necrosis Factor-alpha	1998
DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells. Biochimica et biophysica acta, 1998, Sep-16, Volume: 1404, Issue:3 Topics: Acetylcysteine; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Cytarabine; Deferoxamine; DNA Damage; Etoposide; Gene Expression Regulation; Hydroxyurea; Polyribosomes; RNA, Messenger; Tumor Cells, Cultured; Ubiquitins	1998
Deferoxamine delays the development of the hepatotoxicity of acetaminophen in mice. Toxicology letters, 1999, May-20, Volume: 106, Issue:1 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chelating Agents; Deferoxamine; Dose-Response Relationship, Drug; Kupffer Cells; Liver; Male; Mice	1999
Direct proteasome inhibition by clasto-lactacystin beta-lactone permits the detection of ubiquitinated p21(waf1) in ML-1 cells. Biochimica et biophysica acta, 1999, Aug-12, Volume: 1451, Issue:1 Topics: Acetylcysteine; Antibodies; Blotting, Western; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Deferoxamine; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Lactones; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; Ubiquitins	1999
Safrole-induced oxidative damage in the liver of Sprague-Dawley rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:7 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Alanine Transaminase; Animals; Antidotes; Antioxidants; Aspartate Aminotransferases; Carcinogens; Deferoxamine; Deoxyguanosine; DNA Adducts; DNA Damage; Lipid Peroxides; Liver; Male; Microsomes, Liver; Oxidative Stress; Rats; Rats, Sprague-Dawley; Safrole; Vitamin E	1999
Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease. The Journal of biological chemistry, 1999, Oct-08, Volume: 274, Issue:41 Topics: Acetylcysteine; alpha-Synuclein; Antioxidants; Brain; Cytochrome c Group; Deferoxamine; Humans; Hydrogen Peroxide; Immunohistochemistry; Lewy Body Disease; Nerve Tissue Proteins; Oxidative Stress; Recombinant Proteins; Synucleins	1999
Inhibition of NFkappaB activation with antioxidants is correlated with reduced cytokine transcription in PTC. The American journal of physiology, 1999, Volume: 277, Issue:5 Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Survival; Cytokines; Deferoxamine; Hydrogen Peroxide; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipopolysaccharides; Male; NF-kappa B; Pyrrolidines; Quercetin; Rats; Rats, Wistar; Thiocarbamates; Transcription, Genetic	1999
Ischemia-reperfusion injury of rabbit kidney: comparative effects of desferrioxamine and N-acetylcysteine as antioxidants. Transplantation proceedings, 2000, Volume: 32, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Aspartate Aminotransferases; Deferoxamine; Glutathione; Ischemia; Kidney; Kidney Cortex; L-Lactate Dehydrogenase; Microcirculation; Necrosis; Rabbits; Renal Circulation; Reperfusion Injury; Vitamin E	2000
Effect of N-acetylcysteine and deferoxamine on endogenous antioxidant defense system gene expression in a rat hepatocyte model of cocaine cytotoxicity. Biochimica et biophysica acta, 2000, Apr-17, Volume: 1496, Issue:2-3 Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cells, Cultured; Cocaine; Deferoxamine; Diploidy; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Hydrogen Peroxide; Liver; Male; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase	2000
Effects of clinically used antioxidants in experimental pneumococcal meningitis. The Journal of infectious diseases, 2000, Volume: 182, Issue:1 Topics: Acetylcysteine; Animals; Antioxidants; Deferoxamine; Disease Models, Animal; Meningitis, Pneumococcal; Neurons; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	2000
Effect of cigarette smoke on salivary proteins and enzyme activities. Archives of biochemistry and biophysics, 2000, Jul-15, Volume: 379, Issue:2 Topics: Acetylcysteine; Acid Phosphatase; Amylases; Antioxidants; Ascorbic Acid; Blood Proteins; Deferoxamine; Female; Glutathione; Humans; L-Lactate Dehydrogenase; Male; Nicotiana; Plants, Toxic; Saliva; Salivary Proteins and Peptides; Smoke; Smoking; Time Factors	2000
Glutathione oxidation and PTPase inhibition by hydrogen peroxide in Caco-2 cell monolayer. American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:2 Topics: Acetylcysteine; Antineoplastic Agents, Alkylating; Caco-2 Cells; Carmustine; Catalase; Cell Membrane Permeability; Chelating Agents; Deferoxamine; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Intestinal Mucosa; Intestines; Iron; Maleates; Oxidants; Oxidation-Reduction; Phenanthrolines; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Sulfhydryl Compounds; Superoxide Dismutase; Thiomalates; Tight Junctions; Vitamin A; Vitamin E	2000
Regulation of endothelial heme oxygenase activity during hypoxia is dependent on chelatable iron. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6 Topics: Acetylcysteine; Aminolevulinic Acid; Animals; Aorta, Thoracic; Carbon Monoxide; Cattle; Cell Hypoxia; Cells, Cultured; Deferoxamine; Endothelium, Vascular; Enzyme Activation; Ferric Compounds; Free Radical Scavengers; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hypoxia; Iron Chelating Agents; Male; Oxidative Stress; Phenanthrolines; Photosensitizing Agents; Quaternary Ammonium Compounds	2000
Mitochondrial involvement in cocaine-treated rat hepatocytes: effect of N-acetylcysteine and deferoxamine. British journal of pharmacology, 2001, Volume: 132, Issue:5 Topics: Acetylcysteine; Animals; Apoptosis; Caspase 3; Caspases; Chelating Agents; Cocaine; Cytochrome c Group; Deferoxamine; DNA Fragmentation; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Free Radical Scavengers; Heat-Shock Proteins; Hepatocytes; HSP20 Heat-Shock Proteins; Male; Membrane Potentials; Mitochondria, Liver; Muscle Proteins; Rats; Rats, Wistar	2001
Kupffer cells and neutrophils as paracrine regulators of the heme oxygenase-1 gene in hepatocytes after hemorrhagic shock. Shock (Augusta, Ga.), 2001, Volume: 15, Issue:6 Topics: Acetylcysteine; Animals; Antioxidants; Blood Pressure; Cells, Cultured; Chromans; Clodronic Acid; Deferoxamine; Disease Models, Animal; Gadolinium; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; Kupffer Cells; Male; Neutrophils; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Time Factors; Vinblastine	2001
A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats. British journal of pharmacology, 2001, Volume: 134, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Corpus Striatum; Deferoxamine; Dialysis Solutions; Dopamine; Dose-Response Relationship, Drug; Free Radical Scavengers; Homovanillic Acid; Iron; Male; Metalloporphyrins; Molsidomine; Movement; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Uric Acid	2001
Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide. Cancer research, 2001, Nov-15, Volume: 61, Issue:22 Topics: Acetylcysteine; Animals; Calcineurin; Calcium; Carcinogens; Cells, Cultured; Chelating Agents; Cyclosporine; Deferoxamine; DNA-Binding Proteins; Drug Synergism; Fibroblasts; Free Radical Scavengers; Hydrogen Peroxide; Mice; NFATC Transcription Factors; Nickel; Nuclear Proteins; Reactive Oxygen Species; Thapsigargin; Transcription Factors; Transcriptional Activation; Transfection	2001
Antioxidants inhibit mercuric chloride-induced early vasculitis. International immunology, 2002, Volume: 14, Issue:3 Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; Chymases; Deferoxamine; Immunoenzyme Techniques; Immunoglobulin E; Interleukin-4; Male; Mast Cells; Mercuric Chloride; Pyruvic Acid; Rats; Rats, Inbred BN; Serine Endopeptidases; Vasculitis	2002
Reactive oxygen species generated during myocardial ischemia enable energetic recovery during reperfusion. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4 Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Deferoxamine; Energy Metabolism; Free Radical Scavengers; In Vitro Techniques; Iron Chelating Agents; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Oxidative Stress; Perfusion; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species	2002
Numerous proteins in Mammalian cells are prone to iron-dependent oxidation and proteasomal degradation. Developmental neuroscience, 2002, Volume: 24, Issue:2-3 Topics: Acetylcysteine; Blotting, Western; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Deferoxamine; Ferric Compounds; Humans; Iron; Iron Chelating Agents; Multienzyme Complexes; Oxidation-Reduction; Proteasome Endopeptidase Complex; Proteins; Quaternary Ammonium Compounds; Tumor Cells, Cultured	2002
In vitro activation of dibromoacetonitrile to cyanide: role of xanthine oxidase. Archives of toxicology, 2003, Volume: 77, Issue:2 Topics: Acetonitriles; Acetylcysteine; Catalase; Cyanides; Deferoxamine; Disinfection; Dithiothreitol; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Hypoxanthine; In Vitro Techniques; Oxidation-Reduction; Superoxide Dismutase; Water Pollutants, Chemical; Xanthine Oxidase	2003
A phosphomimetic mutation at Ser-138 renders iron regulatory protein 1 sensitive to iron-dependent degradation. Molecular and cellular biology, 2003, Volume: 23, Issue:19 Topics: Acetylcysteine; Amino Acid Sequence; Animals; Cell Line; Cysteine Proteinase Inhibitors; Deferoxamine; Humans; Iron; Iron Chelating Agents; Iron Regulatory Protein 1; Leupeptins; Mice; Molecular Sequence Data; Mutation; Point Mutation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine	2003
Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain. Brain research. Molecular brain research, 2003, Sep-10, Volume: 117, Issue:1 Topics: Acetylcysteine; Adenylyl Cyclases; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Binding Sites; Case-Control Studies; Cell Membrane; Deferoxamine; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Frontal Lobe; Glutathione; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Humans; Hydrogen Peroxide; Iron Chelating Agents; Oxidants; Peptide Fragments; Sulfur Isotopes	2003
Effect of hypoxia on the expression of fractalkine in human endothelial cells. The Tohoku journal of experimental medicine, 2003, Volume: 200, Issue:4 Topics: Acetylcysteine; Cell Hypoxia; Cells, Cultured; Chemokine CX3CL1; Chemokines, CX3C; Deferoxamine; Endothelial Cells; Endothelium, Vascular; Humans; Interferon-gamma; Iron Chelating Agents; Membrane Proteins; Oxygen; RNA, Messenger; Vascular Endothelial Growth Factor A	2003
Treatment with N-acetylcysteine plus deferoxamine protects rats against oxidative stress and improves survival in sepsis. Critical care medicine, 2004, Volume: 32, Issue:2 Topics: Acetylcysteine; Animals; Deferoxamine; Drug Therapy, Combination; Free Radical Scavengers; Iron Chelating Agents; Male; Oxidative Stress; Prospective Studies; Random Allocation; Rats; Rats, Wistar; Survival Rate	2004
Therapeutic benefits of antioxidants during sepsis: is protection against oxidant-mediated tissue damage only half the story? Critical care medicine, 2004, Volume: 32, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Deferoxamine; Free Radical Scavengers; Humans; Iron Chelating Agents; Oxidative Stress; Sepsis	2004
Modulation of genotoxic effects in asbestos-exposed primary human mesothelial cells by radical scavengers, metal chelators and a glutathione precursor. Mutation research, 2004, Apr-11, Volume: 559, Issue:1-2 Topics: Acetylcysteine; Asbestos, Crocidolite; Asbestos, Serpentine; Chelating Agents; Deferoxamine; Epithelial Cells; Free Radical Scavengers; Humans; Kinetochores; Lysine; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenesis; Phytic Acid; Superoxide Dismutase; Thiourea	2004
Characterization and modulation of the transferrin receptor on brain capillary endothelial cells. Pharmaceutical research, 2004, Volume: 21, Issue:5 Topics: Acetylcysteine; Animals; Astrocytes; Capillaries; Cattle; Cells, Cultured; Cerebrovascular Circulation; Deferoxamine; Down-Regulation; Endocytosis; Endothelial Cells; Extracellular Space; Free Radical Scavengers; Inflammation; Iron; Lipopolysaccharides; Receptors, Transferrin; Transferrin; Tyrphostins	2004
Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats. Critical care medicine, 2004, Volume: 32, Issue:10 Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Deferoxamine; Hydrocarbons; Inflammation; Liver; Liver Failure, Acute; Male; Models, Animal; Necrosis; Oxidative Stress; Rats; Rats, Wistar	2004
Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells. American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:5 Topics: Acetylcysteine; Amino Acids, Dicarboxylic; Cell Hypoxia; Chromans; Deferoxamine; DNA-Binding Proteins; Electron Transport; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mitochondria; Nuclear Proteins; Oligomycins; Proton-Translocating ATPases; Reactive Oxygen Species; Transcription Factors; Tumor Cells, Cultured	2005
Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration. Biochemical and biophysical research communications, 2005, Jul-29, Volume: 333, Issue:2 Topics: Acetylcysteine; Animals; Deferoxamine; Iron Chelating Agents; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Parkinsonian Disorders; Proteasome Inhibitors; Substantia Nigra; Treatment Outcome; Ubiquitin	2005
Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures. International journal of oncology, 2005, Volume: 27, Issue:3 Topics: Acetylcysteine; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; Cell Shape; Cobalt; Deferoxamine; DNA-Binding Proteins; Flow Cytometry; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Necrosis; Nuclear Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factors	2005
Nickel compound-induced DNA single-strand breaks in chromosomal and nuclear chromatin in human blood lymphocytes in vitro: role of oxidative stress and intracellular calcium. Mutation research, 2005, Oct-03, Volume: 586, Issue:2 Topics: Acetylcysteine; Analysis of Variance; Calcium; Catalase; Chromatin; Cytogenetic Analysis; Dantrolene; Deferoxamine; DNA Damage; Egtazic Acid; Humans; In Situ Nick-End Labeling; Lymphocytes; Microscopy, Electron; Mutagenicity Tests; Nickel; Oxidative Stress; Superoxide Dismutase; Thiourea; Verapamil	2005
Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in nickel sulfate-induced human lymphocyte death in vitro. Chemico-biological interactions, 2005, Sep-10, Volume: 156, Issue:1 Topics: Acetylcysteine; Calcium; Catalase; Cell Death; Cyclosporine; Deferoxamine; Glutathione; Homeostasis; Humans; Hydrogen Peroxide; Lymphocytes; Mannitol; Membrane Potentials; Mitochondria; Nickel; Oxidative Stress; Thiourea	2005
N-acetylcysteine and deferoxamine reduce pulmonary oxidative stress and inflammation in rats after coal dust exposure. Environmental research, 2005, Volume: 99, Issue:3 Topics: Acetylcysteine; Animals; Coal; Deferoxamine; Dust; Free Radicals; Inflammation; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Siderophores; Trachea	2005
Effects of N-acetylcysteine plus deferoxamine in lipopolysaccharide-induced acute lung injury in the rat. Critical care medicine, 2006, Volume: 34, Issue:2 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, Animal; Interleukin-1; Lipopolysaccharides; Male; Oxidative Stress; Rats; Rats, Wistar; Respiratory Distress Syndrome; Siderophores; Tumor Necrosis Factor-alpha; Vasodilator Agents	2006
More antioxidants in sepsis: still paved with uncertainties. Critical care medicine, 2006, Volume: 34, Issue:2 Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, Animal; Humans; Oxidation-Reduction; Oxidative Stress; Respiratory Distress Syndrome; Sepsis; Siderophores	2006
Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway. Oncogene, 2007, Jan-11, Volume: 26, Issue:2 Topics: Acetylcysteine; Activating Transcription Factor 3; Amino Acids, Dicarboxylic; Basic Helix-Loop-Helix Transcription Factors; Breast Neoplasms; Cells, Cultured; Cyanides; Deferoxamine; Enzyme Activation; Free Radical Scavengers; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Melanoma; Mixed Function Oxygenases; Neurons; Oxygen; Proto-Oncogene Proteins c-jun; Siderophores; Signal Transduction; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Von Hippel-Lindau Tumor Suppressor Protein	2007
Successful pregnancy outcome following maternal intravenous immunoglobulin treatment in a woman with recurrent perinatal haemochromatosis. Prenatal diagnosis, 2006, Volume: 26, Issue:13 Topics: Acetylcysteine; Adult; Deferoxamine; Diagnosis, Differential; Female; Ferritins; Fetal Diseases; Free Radical Scavengers; Gestational Age; Hemochromatosis; Humans; Hydrops Fetalis; Infant, Newborn; Live Birth; Liver Failure, Acute; Pregnancy; Recurrence; Treatment Outcome; Vitamin E; Vitamin K	2006
Huntingtin inclusion bodies are iron-dependent centers of oxidative events. The FEBS journal, 2006, Volume: 273, Issue:23 Topics: Acetylcysteine; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Deferoxamine; Exons; Heat-Shock Proteins; Huntington Disease; Inclusion Bodies; Iron; Microscopy, Confocal; Oxidation-Reduction; Phenanthridines; Rats; Recombinant Fusion Proteins	2006
Histidine-induced injury to cultured liver cells, effects of histidine derivatives and of iron chelators. Cellular and molecular life sciences : CMLS, 2007, Volume: 64, Issue:2 Topics: Acetylcysteine; Animals; Butylated Hydroxytoluene; Cell Survival; Cells, Cultured; Chromans; Deferoxamine; Hepatocytes; Histidine; Iron Chelating Agents; Lipid Peroxidation; Male; Molecular Structure; Organ Preservation Solutions; Rats; Rats, Wistar	2007
[Prooxidant and cytotoxic action of N-acetylcysteine and glutathione combined with vitamin Bl2b]. Tsitologiia, 2007, Volume: 49, Issue:1 Topics: Acetylcysteine; Antioxidants; Apoptosis; Catalase; Cell Line, Tumor; Cell Physiological Phenomena; Deferoxamine; Drug Synergism; Free Radical Scavengers; Glutathione; Humans; Iron Compounds; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Pyruvic Acid; Siderophores; Vitamin B 12	2007
Oxidative stress and metabolism in animal model of colitis induced by dextran sulfate sodium. Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:11 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; Deferoxamine; Dextran Sulfate; Disease Models, Animal; Electron Transport Complex II; Electron Transport Complex IV; Gastrointestinal Agents; Leukocyte Count; Lipid Peroxidation; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Succinate Dehydrogenase; Thiobarbituric Acid Reactive Substances	2007
Mitochondrial superoxide production is related to the control of cytokine release from peritoneal macrophage after antioxidant treatment in septic rats. The Journal of surgical research, 2007, Volume: 141, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Cytokines; Deferoxamine; Macrophages, Peritoneal; Male; Mitochondria; Rats; Rats, Wistar; Sepsis; Signal Transduction; Superoxides; Thiobarbituric Acid Reactive Substances	2007
Wear particles generated from studded tires and pavement induces inflammatory reactions in mouse macrophage cells. Chemical research in toxicology, 2007, Volume: 20, Issue:6 Topics: Acetylcysteine; Androstadienes; Animals; Cell Line; Cell Survival; Cytokines; Deferoxamine; Free Radical Scavengers; Gene Expression; Inflammation; Interleukin-6; Lipid Peroxidation; Macrophages; Mice; Microscopy, Electron, Scanning; Motor Vehicles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Particulate Matter; Quartz; Reactive Oxygen Species; RNA, Messenger; Silicon Dioxide; Tumor Necrosis Factor-alpha; Wortmannin	2007
Antioxidant treatment prevented late memory impairment in an animal model of sepsis. Critical care medicine, 2007, Volume: 35, Issue:9 Topics: Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Cecum; Deferoxamine; Disease Models, Animal; Habituation, Psychophysiologic; Intestinal Perforation; Ligation; Male; Memory Disorders; Rats; Rats, Wistar; Sepsis	2007
Attenuation of bleomycin-induced lung injury and oxidative stress by N-acetylcysteine plus deferoxamine. Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:2 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Bleomycin; Catalase; Deferoxamine; Drug Therapy, Combination; Fibrosis; Iron Chelating Agents; L-Lactate Dehydrogenase; Lipid Peroxidation; Lung; Lung Diseases; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2008
The effect of n-acetylcysteine and deferoxamine on exercise-induced oxidative damage in striatum and hippocampus of mice. Neurochemical research, 2008, Volume: 33, Issue:5 Topics: Acetylcysteine; Animals; Catalase; Corpus Striatum; Deferoxamine; Hippocampus; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Physical Conditioning, Animal; Superoxide Dismutase	2008
Oxidative stress in red blood cells, platelets and polymorphonuclear leukocytes from patients with myelodysplastic syndrome. European journal of haematology, 2007, Volume: 79, Issue:6 Topics: Acetylcysteine; Aged; Aged, 80 and over; Antioxidants; Blood Platelets; Chelating Agents; Deferiprone; Deferoxamine; Erythrocytes; Female; Humans; Male; Myelodysplastic Syndromes; Neutrophils; Oxidative Stress; Pyridones	2007
Inhibitory effect of 6-formylpterin on HIF-1alpha protein accumulation. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:11 Topics: Acetylcysteine; Antioxidants; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Deferoxamine; Dose-Response Relationship, Drug; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Pterins; Reactive Oxygen Species; RNA, Messenger	2007
Inhibition of brain creatine kinase activity after renal ischemia is attenuated by N-acetylcysteine and deferoxamine administration. Neuroscience letters, 2008, Mar-21, Volume: 434, Issue:1 Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Diseases, Metabolic; Creatine Kinase; Deferoxamine; Down-Regulation; Ischemia; Kidney Diseases; Male; Nerve Degeneration; Oxidative Stress; Rats; Rats, Wistar; Subcellular Fractions; Time Factors; Treatment Outcome; Uremia	2008
Effect of N-acetylcysteine and/or deferoxamine on oxidative stress and hyperactivity in an animal model of mania. Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4 Topics: Acetylcysteine; Animals; Bipolar Disorder; Central Nervous System Stimulants; Deferoxamine; Dextroamphetamine; Free Radical Scavengers; Hyperkinesis; Male; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar	2008
TNF-alpha stimulates Akt by a distinct aPKC-dependent pathway in premalignant keratinocytes. Experimental dermatology, 2008, Volume: 17, Issue:12 Topics: Acetylcysteine; Androstadienes; Apoptosis; Blotting, Western; Caspases; Cell Line; Cell Survival; Chromones; Deferoxamine; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Keratinocytes; Leupeptins; Morpholines; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Tocopherols; Tumor Necrosis Factor-alpha; Wortmannin	2008
Efficacy of the combination of N-acetylcysteine and desferrioxamine in the prevention and treatment of gentamicin-induced acute renal failure in male Wistar rats. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:7 Topics: Acetylcysteine; Acute Kidney Injury; Animals; Deferoxamine; Drug Therapy, Combination; Free Radical Scavengers; Gentamicins; Male; Rats; Rats, Wistar; Siderophores	2009
Effects of N-acetylcysteine, deferoxamine and selenium on doxorubicin-induced hepatotoxicity. Biological trace element research, 2009, Volume: 132, Issue:1-3 Topics: Acetylcysteine; Animals; Catalase; Copper; Deferoxamine; Doxorubicin; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Selenium; Superoxide Dismutase; Zinc	2009
Antioxidant treatment reverses organ failure in rat model of sepsis: role of antioxidant enzymes imbalance, neutrophil infiltration, and oxidative stress. The Journal of surgical research, 2011, May-15, Volume: 167, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Deferoxamine; Disease Models, Animal; Kidney; Lung; Male; Multiple Organ Failure; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Urea	2011
Effects of N-acetylcysteine/deferoxamine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis. Neurochemical research, 2010, Volume: 35, Issue:4 Topics: Acetylcysteine; Animals; Bombesin; Brain; Creatine Kinase; Deferoxamine; Electron Transport; Male; Peptide Fragments; Rats; Rats, Wistar; Sepsis; Taurine	2010
Inhibition of mitochondrial respiratory chain in the brain of rats after renal ischemia is prevented by N-acetylcysteine and deferoxamine. Metabolic brain disease, 2010, Volume: 25, Issue:2 Topics: Acetylcysteine; Animals; Cell Respiration; Deferoxamine; Disease Models, Animal; Drug Combinations; Drug Synergism; Electron Transport; Electron Transport Complex I; Free Radical Scavengers; Ischemia; Kidney Diseases; Male; Rats; Rats, Wistar	2010
Inhibition of mitochondrial respiratory chain in the brain of rats after hepatic failure induced by acetaminophen. Molecular and cellular biochemistry, 2011, Volume: 350, Issue:1-2 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Brain; Deferoxamine; Down-Regulation; Drug Evaluation, Preclinical; Electron Transport; Liver Failure; Male; Mitochondria; Rats; Rats, Wistar; Taurine	2011
Therapeutic management of neonatal hemochromatosis: report of four cases and literature review. Human & experimental toxicology, 2011, Volume: 30, Issue:10 Topics: Acetylcysteine; Antioxidants; Deferoxamine; Female; Hemochromatosis; Humans; Infant, Newborn; Selenium; Siderophores; Vitamin E	2011
Novel cytochrome p450 bioactivation of a terminal phenyl acetylene group: formation of a one-carbon loss benzaldehyde and other oxidative products in the presence of N-acetyl cysteine or glutathione. Chemical research in toxicology, 2011, May-16, Volume: 24, Issue:5 Topics: Acetylcysteine; Acetylene; Animals; Antioxidants; Ascorbic Acid; Benzaldehydes; Cattle; Chelating Agents; Cytochrome P-450 Enzyme System; Deferoxamine; Dogs; Glutathione; Humans; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley	2011
Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds. FEBS letters, 2011, Apr-20, Volume: 585, Issue:8 Topics: Acetylcysteine; alpha-Synuclein; Antioxidants; Apigenin; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Humans; Iron Chelating Agents; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Structure; Mutation; Parkinson Disease; Phenols; Polyphenols; Protein Multimerization; Protein Structure, Quaternary; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship	2011
Antioxidant administration prevents memory impairment in an animal model of maple syrup urine disease. Behavioural brain research, 2012, May-16, Volume: 231, Issue:1 Topics: Acetylcysteine; Amino Acids, Branched-Chain; Animals; Antioxidants; Deferoxamine; Disease Models, Animal; Male; Maple Syrup Urine Disease; Memory; Memory Disorders; Rats; Rats, Wistar	2012
Antioxidant treatment prevents cognitive impairment and oxidative damage in pneumococcal meningitis survivor rats. Metabolic brain disease, 2012, Volume: 27, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Behavior, Animal; Cerebral Cortex; Cognition Disorders; Deferoxamine; Free Radical Scavengers; Habituation, Psychophysiologic; Hippocampus; Lipid Peroxidation; Male; Memory; Meningitis, Pneumococcal; Oxidative Stress; Rats; Rats, Wistar; Survivors; Thiobarbituric Acid Reactive Substances	2012
Synergist effects of n-acetylcysteine and deferoxamine treatment on behavioral and oxidative parameters induced by chronic mild stress in rats. Neurochemistry international, 2012, Volume: 61, Issue:7 Topics: Acetylcysteine; Animals; Behavior, Animal; Deferoxamine; Drug Synergism; Oxidative Stress; Rats; Stress, Psychological; Thiobarbituric Acid Reactive Substances	2012
Implication of glutathione in the in vitro antiplasmodial mechanism of action of ellagic acid. PloS one, 2012, Volume: 7, Issue:9 Topics: Acetylcysteine; Animals; Antimalarials; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Cells, Cultured; Deferoxamine; Drug Synergism; Ellagic Acid; Enzyme Inhibitors; Erythrocytes; Glutathione; Humans; Inhibitory Concentration 50; Mice; Oxidation-Reduction; Plasmodium falciparum; Plasmodium yoelii; Reactive Oxygen Species; Siderophores	2012
Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model. Journal of inherited metabolic disease, 2013, Volume: 36, Issue:5 Topics: Acetylcysteine; Amino Acids, Branched-Chain; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Deferoxamine; Disease Models, Animal; Hippocampus; Male; Maple Syrup Urine Disease; Memory; Memory Disorders; Oxidative Stress; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger	2013
Cross-talk between microRNAs, nuclear factor E2-related factor 2, and heme oxygenase-1 in ochratoxin A-induced toxic effects in renal proximal tubular epithelial cells. Molecular nutrition & food research, 2013, Volume: 57, Issue:3 Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Deferoxamine; Epithelial Cells; Erythropoietin; Gene Expression Regulation; Heme Oxygenase-1; Kidney Tubules, Proximal; MicroRNAs; NF-E2-Related Factor 2; Ochratoxins; Reactive Oxygen Species; Signal Transduction; Swine; Transforming Growth Factor beta	2013
N-acetylcysteine ameliorates acute kidney injury but not glomerular hemorrhage in an animal model of warfarin-related nephropathy. American journal of physiology. Renal physiology, 2013, Jun-15, Volume: 304, Issue:12 Topics: Acetylcysteine; Acute Kidney Injury; Animals; Creatinine; Deferoxamine; Erythrocytes; Male; Nephrectomy; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Urine; Warfarin	2013
Deferoxamine promotes osteoblastic differentiation in human periodontal ligament cells via the nuclear factor erythroid 2-related factor-mediated antioxidant signaling pathway. Journal of periodontal research, 2014, Volume: 49, Issue:5 Topics: Acetylcysteine; Antioxidant Response Elements; Buthionine Sulfoximine; Calcification, Physiologic; Calcium; Cell Differentiation; Cell Line; Deferoxamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Maleates; MAP Kinase Signaling System; NF-E2-Related Factor 2; NF-kappa B; Osteoblasts; Periodontal Ligament; Reactive Oxygen Species; RNA, Small Interfering; Siderophores; Signal Transduction; Vitamin E	2014
Methemoglobin-induced signaling and chemokine responses in human alveolar epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2014, Jan-01, Volume: 306, Issue:1 Topics: Acetylcysteine; Alveolar Epithelial Cells; Antioxidants; Cell Line, Tumor; Chemokine CCL2; Chemokines; Deferoxamine; Gene Knockdown Techniques; Humans; I-kappa B Kinase; Interleukin-8; Iron Chelating Agents; MAP Kinase Signaling System; Methemoglobin; NF-kappa B; Oxidative Stress; Phenanthrolines; Phosphorylation; Protein Processing, Post-Translational; Pulmonary Alveoli; RNA Interference	2014
The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. The Journal of biological chemistry, 2014, Nov-28, Volume: 289, Issue:48 Topics: Acetylcysteine; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Survival; Copper; Deferoxamine; Female; Free Radical Scavengers; Humans; Iron; Lysosomes; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Phagosomes; Siderophores; Thiosemicarbazones	2014
Effect of N-acetylcysteine plus deferoxamine on oxidative stress and inflammation in dystrophic muscle cells. Redox report : communications in free radical research, 2015, Volume: 20, Issue:3 Topics: Acetylcysteine; Aldehydes; Animals; Cells, Cultured; Deferoxamine; Hydrogen Peroxide; Inflammation; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NF-kappa B; Oxidative Stress; Tumor Necrosis Factor-alpha	2015
Organic extracts from African dust storms stimulate oxidative stress and induce inflammatory responses in human lung cells through Nrf2 but not NF-κB. Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:2 Topics: Acetylcysteine; Africa; Air Movements; Air Pollutants; Cell Line; Deferoxamine; Dust; Glutathione S-Transferase pi; Heme Oxygenase-1; Humans; Inflammation; Interleukin-6; Interleukin-8; Lung; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Puerto Rico; Reactive Oxygen Species; RNA, Messenger	2015
The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania. Journal of psychiatric research, 2015, Volume: 65 Topics: Acetylcysteine; Aldehydes; Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Brain; Deferoxamine; Disease Models, Animal; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Sleep Deprivation; Tyrosine	2015
N-acetylcysteine Plus Deferoxamine Improves Cardiac Function in Wistar Rats After Non-reperfused Acute Myocardial Infarction. Journal of cardiovascular translational research, 2015, Volume: 8, Issue:5 Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Deferoxamine; Echocardiography; Immunohistochemistry; Iron; Iron Chelating Agents; Male; Myocardial Infarction; Myocardium; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Stroke Volume; Sulfhydryl Compounds; Troponin I; Ventricular Function	2015
Antioxidant treatment ameliorates experimental diabetes-induced depressive-like behaviour and reduces oxidative stress in brain and pancreas. Diabetes/metabolism research and reviews, 2016, Volume: 32, Issue:3 Topics: Acetylcysteine; Animals; Antioxidants; Behavior, Animal; Brain; Deferoxamine; Depressive Disorder; Diabetes Mellitus, Experimental; Free Radical Scavengers; Lipid Peroxidation; Male; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Siderophores	2016
Antioxidant Therapy Alters Brain MAPK-JNK and BDNF Signaling Path-ways in Experimental Diabetes Mellitus. Current neurovascular research, 2016, Volume: 13, Issue:2 Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Brain; Brain-Derived Neurotrophic Factor; Deferoxamine; Diabetes Mellitus, Experimental; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Signal Transduction	2016
The effects of antioxidants on a porcine model of liver hemorrhage. The journal of trauma and acute care surgery, 2016, Volume: 80, Issue:6 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Crystalloid Solutions; Deferoxamine; Disease Models, Animal; Hepatectomy; Immunohistochemistry; Isotonic Solutions; Liver; Male; Random Allocation; Resuscitation; Shock, Hemorrhagic; Swine	2016
A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload. Neuroscience, 2016, 09-22, Volume: 332 Topics: Acetylcysteine; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Benzoates; Brain; Deferasirox; Deferoxamine; Dendrites; Diet; Disease Models, Animal; Drug Therapy, Combination; Iron; Iron Chelating Agents; Iron Overload; Male; Mitochondrial Dynamics; Neurodegenerative Diseases; Phosphorylation; Random Allocation; Rats, Wistar; tau Proteins; Triazoles	2016
Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats. PloS one, 2016, Volume: 11, Issue:7 Topics: Acetylcysteine; Animals; Benzoates; Cardiomyopathies; Cardiotonic Agents; Deferasirox; Deferiprone; Deferoxamine; Drug Combinations; Drug Synergism; Humans; Iron; Iron Chelating Agents; Iron Overload; Iron, Dietary; Male; Malondialdehyde; Mitochondria; Pyridones; Rats; Rats, Wistar; Triazoles; Ventricular Function, Left	2016
N-Acetylcysteine and Desferoxamine Reduce Pulmonary Oxidative Stress Caused by Hemorrhagic Shock in a Porcine Model. Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2017, Volume: 30, Issue:1 Topics: Acetylcysteine; Animals; Biomarkers; Colloids; Crystalloid Solutions; Deferoxamine; Disease Models, Animal; Drug Evaluation, Preclinical; Fluid Therapy; Free Radical Scavengers; Glutathione Peroxidase; Humans; Infusions, Intravenous; Isotonic Solutions; Lung; Male; Oxidative Stress; Protein Carbonylation; Random Allocation; Rehydration Solutions; Shock, Hemorrhagic; Siderophores; Swine; Thiobarbituric Acid Reactive Substances	2017
Antioxidants reverse the changes in energy metabolism of rat brain after chronic administration of L.-tyrosine. Metabolic brain disease, 2017, Volume: 32, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Brain Chemistry; Citrate (si)-Synthase; Citric Acid Cycle; Creatine Kinase; Deferoxamine; Electron Transport; Energy Metabolism; Male; Oxidative Stress; Rats; Rats, Wistar; Succinate Dehydrogenase; Tyrosine; Tyrosinemias	2017
Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells. American journal of physiology. Renal physiology, 2018, 05-01, Volume: 314, Issue:5 Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Carbolines; Cell Death; Cell Line; Cyclohexylamines; Deferoxamine; Dose-Response Relationship, Drug; Ferric Compounds; Glutathione; Heme Oxygenase-1; Iron Chelating Agents; Kidney Tubules, Proximal; Membrane Proteins; Mice, Knockout; Phenylenediamines; Piperazines; Quaternary Ammonium Compounds; Signal Transduction; Time Factors	2018
Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis. International journal of oncology, 2018, Volume: 52, Issue:3 Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Line, Tumor; Cyclohexylamines; Deferoxamine; Dioxolanes; Diterpenes; Drug Synergism; Fibroblasts; Humans; Iron; Mice; Pancreatic Neoplasms; Phenylenediamines; Quinoxalines; Reactive Oxygen Species; Spiro Compounds; Sulfasalazine	2018
Antioxidants Reverse the Changes in the Cholinergic System Caused by L-Tyrosine Administration in Rats. Neurotoxicity research, 2018, Volume: 34, Issue:4 Topics: Acetylcholinesterase; Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Brain; Choline O-Acetyltransferase; Deferoxamine; Male; Memory; Neuroprotective Agents; Rats, Wistar; Tyrosine	2018
Role of iron and oxidative stress in the exacerbation of allergic inflammation in murine lungs caused by urban particulate matter <2.5 μm and desert dust. Journal of applied toxicology : JAT, 2019, Volume: 39, Issue:6 Topics: Acetylcysteine; Animals; Asthma; Cytokines; Deferoxamine; Dust; Iron; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Particulate Matter; Trace Elements	2019
Cold storage of porcine hepatocyte spheroids for spheroid bioartificial liver. Xenotransplantation, 2019, Volume: 26, Issue:4 Topics: Acetylcysteine; Albumins; Ammonia; Animals; Cryopreservation; Deferoxamine; Glucose; Hepatocytes; Iron Chelating Agents; Liver, Artificial; Mannitol; Metabolic Clearance Rate; Organ Preservation Solutions; Oxidation-Reduction; Potassium Chloride; Procaine; Spheroids, Cellular; Swine; Transplantation, Heterologous	2019
Stratification to predict the response to antioxidant. Revista Brasileira de terapia intensiva, 2020, Volume: 32, Issue:1 Topics: Acetylcysteine; Adult; Aged; Animals; Antioxidants; Deferoxamine; Humans; Male; Middle Aged; Prognosis; Rats; Rats, Wistar; Retrospective Studies; Sepsis; Treatment Outcome	2020
Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease. The Journal of biological chemistry, 2021, Volume: 297, Issue:2 Topics: Acetylcysteine; Animals; Anthelmintics; Astrocytes; Deferoxamine; Disease Models, Animal; Free Radical Scavengers; Male; Mice; Microglia; Morris Water Maze Test; Neurodegenerative Diseases; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Siderophores	2021
Proteomic Investigation of the Antibacterial Mechanism of Cefiderocol against Escherichia coli. Microbiology spectrum, 2022, 10-26, Volume: 10, Issue:5 Topics: Acetylcysteine; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Deferoxamine; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Iron; NAD; NADP; Proteomics; Quinones; Reactive Oxygen Species; Siderophores; Sulfur	2022
RSL3 Inhibits Porcine Epidemic Diarrhea Virus Replication by Activating Ferroptosis. Viruses, 2023, 10-12, Volume: 15, Issue:10 Topics: Acetylcysteine; Animals; Chlorocebus aethiops; Coronavirus Infections; Deferoxamine; Diarrhea; Ferroptosis; Porcine epidemic diarrhea virus; Swine; Swine Diseases; Vero Cells; Virus Replication	2023