Compounds > acetylcysteine

acetylcysteine and deferasirox

acetylcysteine has been researched along with deferasirox in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chattipakorn, N; Chattipakorn, SC; Krintratun, W; Sripetchwandee, J; Wongjaikam, S1
Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Khamseekaew, J; Kumfu, S; Srichairatanakool, S; Sripetchwandee, J; Wongjaikam, S1
Shen, JC; Zhang, YC; Zhao, MF1
Abedi, M; Esmaeili, A; Rahgozar, S1
Jia, C; Li, M; Li, W; Liu, H; Peng, Y; Su, M; Zhang, Y; Zhao, Y; Zheng, J1

Reviews

1 review(s) available for acetylcysteine and deferasirox

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for acetylcysteine and deferasirox

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload.
    Neuroscience, 2016, 09-22, Volume: 332

    Topics: Acetylcysteine; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Benzoates; Brain; Deferasirox; Deferoxamine; Dendrites; Diet; Disease Models, Animal; Drug Therapy, Combination; Iron; Iron Chelating Agents; Iron Overload; Male; Mitochondrial Dynamics; Neurodegenerative Diseases; Phosphorylation; Random Allocation; Rats, Wistar; tau Proteins; Triazoles

2016
Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Acetylcysteine; Animals; Benzoates; Cardiomyopathies; Cardiotonic Agents; Deferasirox; Deferiprone; Deferoxamine; Drug Combinations; Drug Synergism; Humans; Iron; Iron Chelating Agents; Iron Overload; Iron, Dietary; Male; Malondialdehyde; Mitochondria; Pyridones; Rats; Rats, Wistar; Triazoles; Ventricular Function, Left

2016
Protective effects of deferasirox and N-acetyl-L-cysteine on iron overload-injured bone marrow.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Oct-19, Volume: 50, Issue:12

    Topics: Acetylcysteine; Animals; Benzoates; Colony-Forming Units Assay; Deferasirox; Disease Models, Animal; Flow Cytometry; Free Radical Scavengers; Hematopoiesis; Hematopoietic Stem Cells; Iron Chelating Agents; Iron Overload; Male; Mice, Inbred C57BL; Protective Agents; Reactive Oxygen Species; Reference Values; Reproducibility of Results; Time Factors; Treatment Outcome; Triazoles

2017
Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity.
    Cancer medicine, 2020, Volume: 9, Issue:10

    Topics: Acetylcysteine; Bone Marrow; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Deferasirox; Drug Resistance, Neoplasm; Female; Ferric Compounds; Free Radical Scavengers; Humans; Infant; Inhibitory Concentration 50; Iron; Iron Chelating Agents; Male; Methotrexate; Multidrug Resistance-Associated Proteins; NF-E2-Related Factor 2; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-bcl-2; Quaternary Ammonium Compounds; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Transcriptome; Up-Regulation

2020
Evidence for the Metabolic Activation of Deferasirox
    Chemical research in toxicology, 2023, 08-21, Volume: 36, Issue:8

    Topics: Acetylcysteine; Activation, Metabolic; Animals; Deferasirox; Glutathione; Hepatocytes; Liver; Microsomes, Liver; Rats

2023