acetylcysteine and decitabine

acetylcysteine has been researched along with decitabine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Capanni, C; Columbaro, M; D'Apice, MR; Foisner, R; Lattanzi, G; Maraldi, NM; Mattioli, E; Novelli, G; Riccio, M; Santi, S; Squarzoni, S1
Jung, G; Lim, SO; Quan, X1
Ko, JL; Lee, H; Tang, SC; Wang, PH; Wu, CH1
Choi, YH; Han, MH; Kang, HS; Kim, GY; Kim, WJ; Park, YS; Shin, DY; Yang, K1
Chen, M; Dasgupta, C; Hu, XQ; Xiao, D; Yang, S; Zhang, L1
Fu, R; Huang, L; Jiang, H; Li, L; Liu, Z1
Cai, Z; Chen, N; Guo, Z; Li, H; Li, K; Wang, L; Wang, Q; Wu, S; Zhan, Y; Zhang, Z; Zheng, F1
Cai, C; Han, Y; He, X; Hu, X; Kang, H; Liu, S; Liu, Y; Ma, X; Pan, T; Qi, J; Tang, Y; Wu, D; Yao, Y; Zhang, Z; Zhou, M1

Reviews

1 review(s) available for acetylcysteine and decitabine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for acetylcysteine and decitabine

ArticleYear
Conditioning therapy with N-acetyl-L-cysteine, decitabine and modified BUCY regimen for myeloid malignancies patients prior to allogeneic hematopoietic stem cell transplantation.
    American journal of hematology, 2023, Volume: 98, Issue:6

    Topics: Acetylcysteine; Behavior Therapy; Busulfan; Decitabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Myeloproliferative Disorders; Neoplasms; Prospective Studies; Reactive Oxygen Species; Transplantation Conditioning

2023

Other Studies

9 other study(ies) available for acetylcysteine and decitabine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Drugs affecting prelamin A processing: effects on heterochromatin organization.
    Experimental cell research, 2008, Feb-01, Volume: 314, Issue:3

    Topics: Acetylcysteine; Adult; Antimetabolites, Antineoplastic; Azacitidine; Cell Nucleus; Cells, Cultured; Chromatin Assembly and Disassembly; Decitabine; DNA-Binding Proteins; Enzyme Inhibitors; Farnesyltranstransferase; Fibroblasts; Heterochromatin; Humans; Lamin Type A; Membrane Proteins; Methionine; Nuclear Lamina; Nuclear Proteins; Protein Precursors; Protein Prenylation

2008
Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter.
    FEBS letters, 2011, Nov-04, Volume: 585, Issue:21

    Topics: Acetylcysteine; Azacitidine; Carcinoma, Hepatocellular; Catalase; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Neoplasm Invasiveness; Octamer Transcription Factor-1; Promoter Regions, Genetic; Reactive Oxygen Species

2011
Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation.
    The Journal of biological chemistry, 2012, Jul-20, Volume: 287, Issue:30

    Topics: Acetylcysteine; Antigens, Differentiation; Azacitidine; Bronchi; Cadherins; Cell Line, Transformed; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibronectins; Free Radical Scavengers; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Junctions; Nickel; Pulmonary Fibrosis; Reactive Oxygen Species; Respiratory Mucosa

2012
Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation.
    International journal of oncology, 2012, Volume: 41, Issue:3

    Topics: Acetylcysteine; Apoptosis; Azacitidine; Baculoviral IAP Repeat-Containing 3 Protein; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Decitabine; Down-Regulation; Enzyme Inhibitors; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein

2012
Hypoxia Represses ER-α Expression and Inhibits Estrogen-Induced Regulation of Ca2+-Activated K+ Channel Activity and Myogenic Tone in Ovine Uterine Arteries: Causal Role of DNA Methylation.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 66, Issue:1

    Topics: Acetylcysteine; Animals; Azacitidine; Decitabine; DNA Methylation; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation; Hypoxia; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Pregnancy; Pregnancy Complications; Progesterone; Promoter Regions, Genetic; Reactive Oxygen Species; Sheep; Uterine Artery; Vascular Resistance

2015
Decitabine shows synergistic effects with arsenic trioxide against myelodysplastic syndrome cells via endoplasmic reticulum stress-related apoptosis.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2019, Volume: 67, Issue:7

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Arsenic Trioxide; Cell Line, Tumor; Cell Proliferation; Decitabine; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Myelodysplastic Syndromes; Reactive Oxygen Species

2019
Reactive oxygen species regulate miR-17-5p expression via DNA methylation in paraquat-induced nerve cell damage.
    Environmental toxicology, 2020, Volume: 35, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Culture Techniques; Cell Line, Tumor; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Mice; MicroRNAs; Neurons; Oxidative Stress; Paraquat; Reactive Oxygen Species; Up-Regulation

2020