Compounds > acetylcysteine

acetylcysteine and daunorubicin

acetylcysteine has been researched along with daunorubicin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Allouche, M; Bailly, JD; Bordier, C; Come, MG; Duchayne, E; Laurent, G; Mansat, V; Quillet-Mary, A1
Bettaïeb, A; Bezombes, C; D'orgeix, AD; Jaffrézou, JP; Laurent, G; Mansat-de Mas, V; Quillet-Mary, A1
Bezombes, C; Demur, C; Filomenko, R; Hernandez, H; Jaffrézou, JP; Laurent, G; Maestre, N; Mas, VM; Plo, I; Quillet-Mary, A1
Han, X; Luo, Z; Wang, H; Xuan, Z; Zhong, J; Zhong, L1
Gajek, A; Jóźwiak, Z; Marczak, A; Rogalska, A; Szwed, M1

Reviews

1 review(s) available for acetylcysteine and daunorubicin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for acetylcysteine and daunorubicin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines.
    Leukemia, 1996, Volume: 10, Issue:3

    Topics: Acetylcysteine; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Differentiation; Daunorubicin; DNA Damage; DNA Nucleotidylexotransferase; DNA, Neoplasm; Free Radical Scavengers; Humans; Leukemia, Myeloid, Acute; Methionine Sulfoximine; Nucleosomes; Pyrrolidines; Thiocarbamates; Tumor Cells, Cultured; Verapamil

1996
Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin.
    Molecular pharmacology, 1999, Volume: 56, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Ceramides; Daunorubicin; Drug Interactions; Electron Transport; Enzyme Activation; Free Radical Scavengers; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Mitochondria; Mitogen-Activated Protein Kinases; Pyrrolidines; Reactive Oxygen Species; Sphingomyelin Phosphodiesterase; Thiocarbamates; Transcription Factor AP-1; U937 Cells

1999
Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin.
    Blood, 2003, Feb-15, Volume: 101, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antioxidants; Bridged-Ring Compounds; Cell Death; Daunorubicin; Diglycerides; Enzyme Activation; Flavonoids; Humans; Leukemia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norbornanes; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-raf; Reactive Oxygen Species; Thiocarbamates; Thiones; Transfection; Tumor Cells, Cultured; Wortmannin

2003
Astragalus membranaceus prevents daunorubicin-induced apoptosis of cultured neonatal cardiomyocytes: role of free radical effect of Astragalus membranaceus on daunorubicin cardiotoxicity.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:6

    Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Astragalus propinquus; Cells, Cultured; Daunorubicin; Drugs, Chinese Herbal; L-Lactate Dehydrogenase; Mitochondria; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase

2009
The role of reactive oxygen species in WP 631-induced death of human ovarian cancer cells: a comparison with the effect of doxorubicin.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:8

    Topics: Acetylcysteine; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Membrane Potential, Mitochondrial; Ovarian Neoplasms; Reactive Oxygen Species

2011