acetylcysteine has been researched along with dactinomycin in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (36.36) | 18.2507 |
| 2000's | 14 (42.42) | 29.6817 |
| 2010's | 7 (21.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Clark, BD; Faggioni, R; Gatti, S; Ghezzi, P; Mantovani, A; Mengozzi, M; Orencole, SF; Peristeris, P; Sironi, M | 1 |
| Godleski, JJ; Paulauskis, JD; Shi, MM | 1 |
| Faller, DV; Phelan, MW | 1 |
| Farinelli, SE; Greene, LA; Park, DS; Stefanis, L; Yan, CY | 1 |
| Blagosklonny, MV; el-Deiry, WS; Omura, S; Wu, GS | 1 |
| Balsano, C; Costanzo, A; Ianni, A; Levrero, M; Natoli, G; Templeton, DJ; Woodgett, JR | 1 |
| Bernard-Pomier, G; Charpentier, B; Déas, O; Dumont, C; Hirsch, F; Métivier, D; Mollereau, B; Pasquier, C; Senik, A | 1 |
| Asahi, M; Che, W; Higashiyama, S; Kaneto, H; Okado, A; Takahashi, M; Taniguchi, N | 1 |
| Choi, YH; Henkart, PA; Jang, JS; Lee, J; Lee, SJ; Maki, M; Nguyen, P; Takano, E; Trepel, JB; Wu, ML | 1 |
| Fischer, JE; Hasselgren, PO; Hobler, SC; Monaco, J; Tiao, G | 1 |
| Igisu, H; Matsuno, K; Matsuoka, M; Wispriyono, B | 1 |
| Chua, BH; Chua, CC; Hamdy, RC | 1 |
| Dallaporta, B; Daugas, E; Kroemer, G; Loeffler, M; Maisse, C; Pablo, M; Zamzami, N | 1 |
| Benítez, S; Caveda, L; De Castellarnau, C; Ordóñez-Llanos, J; Rosa, R; Sánchez-Quesada, JL; Vila, L | 1 |
| Levine, L | 1 |
| Grant, S; Vrana, JA | 1 |
| Bens, M; Bianchi, M; Cluzeaud, F; Feraille, E; Hasler, U; Martin, PY; Mordasini, D; Rousselot, M; Vandewalle, A | 1 |
| Hopkins, RG; Loo, G; Powolny, A; Takahashi, K | 1 |
| Jung, MJ; Kweon, MH; Sung, HC | 1 |
| Gao, F; Shi, GY; Tang, XM; Yi, J; Yuan, JQ | 1 |
| Bonanou, S; Chachami, G; Hatziefthimiou, A; Molyvdas, PA; Paraskeva, E; Simos, G | 1 |
| Fujiwara, N; Koh, YH; Misonou, Y; Miyamoto, Y; Park, YS; Suzuki, K; Takahashi, M; Taniguchi, N | 1 |
| Arakawa, H; Bortolin-Cavaillé, ML; Buerstedde, JM; Cavaillé, J; Hainaut, P; Kinomura, A; Messaoudi, L; Stavreva, DA; Takata, M; Van Dyck, E; Yan, G; Yang, YG | 1 |
| He, Q; Joseph, P; Umbright, C | 1 |
| Gorospe, M; Kawai, T; Otto, K; Rinker-Schaeffer, CW; Robinson, VL; Shalhav, O | 1 |
| Bellomo, F; Corallini, S; Emma, F; Palma, A; Pastore, A; Taranta, A | 1 |
| Jitsukawa, M; Kyogoku, H; Miyano, T; Ogushi, S | 1 |
| Dong, Y; Guo, X; Li, C; Ni, C; Xie, Z; Zhang, Y | 1 |
1 review(s) available for acetylcysteine and dactinomycin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
32 other study(ies) available for acetylcysteine and dactinomycin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
N-acetylcysteine and glutathione as inhibitors of tumor necrosis factor production.
Topics: Acetylcysteine; Animals; Cells, Cultured; Corticosterone; Dactinomycin; Glutathione; Interleukin-1; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Serum Amyloid A Protein; Tumor Necrosis Factor-alpha | 1992 |
Regulation of macrophage inflammatory protein-1alpha mRNA by oxidative stress.
Topics: Acetylcysteine; Animals; Blotting, Northern; Cell Nucleus; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Cycloheximide; Dactinomycin; Gene Expression Regulation; Growth Inhibitors; Hydrogen Peroxide; Kinetics; Macrophage Inflammatory Proteins; Macrophages, Alveolar; Monokines; Oxidative Stress; Rats; RNA, Messenger; Time Factors; Transcription, Genetic; Vitamin K | 1996 |
Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells.
Topics: Acetylcysteine; Animals; Bradykinin; Cattle; Cell Hypoxia; Cells, Cultured; Cobalt; Dactinomycin; Endothelin-1; Endothelins; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Nitric Oxide Synthase; Oxygen; Proline; Protein Precursors; RNA, Messenger; Suppression, Genetic; Thiocarbamates; Umbilical Veins | 1996 |
Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells.
Topics: Acetylcysteine; Animals; Apoptosis; Apoptosis Regulatory Proteins; Aurintricarboxylic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Caspase 1; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cysteine Endopeptidases; Dactinomycin; Deferoxamine; Enzyme Activation; Humans; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Nerve Growth Factors; PC12 Cells; Rats; RNA; Serpins; Viral Proteins | 1996 |
Proteasome-dependent regulation of p21WAF1/CIP1 expression.
Topics: Acetylcysteine; Cell Line; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Luciferases; Multienzyme Complexes; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Biosynthesis; Recombinant Proteins; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1996 |
Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Line; Dactinomycin; Enzyme Activation; Fas-Associated Death Domain Protein; Free Radical Scavengers; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinases; NF-kappa B; Protein Serine-Threonine Kinases; Proteins; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Signal Transduction; TNF Receptor-Associated Factor 1; TNF Receptor-Associated Factor 2; Transfection; Tumor Necrosis Factor-alpha | 1997 |
Thiol-mediated inhibition of FAS and CD2 apoptotic signaling in activated human peripheral T cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Buthionine Sulfoximine; CD2 Antigens; Cells, Cultured; Cycloheximide; Dactinomycin; fas Receptor; Female; Glutathione; Humans; Lymphocyte Activation; Male; Signal Transduction; Sulfhydryl Compounds; T-Lymphocytes | 1997 |
Selective induction of heparin-binding epidermal growth factor-like growth factor by methylglyoxal and 3-deoxyglucosone in rat aortic smooth muscle cells. The involvement of reactive oxygen species formation and a possible implication for atherogenesis in
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Arteriosclerosis; Cell Nucleus; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyglucose; Diabetic Angiopathies; Epidermal Growth Factor; Gene Expression; Guanidines; Heparin; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Kinetics; Muscle, Smooth, Vascular; Peroxides; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Transcription, Genetic | 1997 |
Regulation of cyclin D1 by calpain protease.
Topics: 3T3 Cells; Acetylcysteine; Animals; Calpain; Cyclin B; Cyclin B1; Cyclin D1; Cysteine Proteinase Inhibitors; Dactinomycin; Half-Life; Humans; Male; Mice; Prostatic Neoplasms; Protein Synthesis Inhibitors; Tumor Cells, Cultured | 1997 |
Sepsis-induced increase in muscle proteolysis is blocked by specific proteasome inhibitors.
Topics: Acetylcysteine; Animals; Cecum; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Kinetics; Leupeptins; Male; Multienzyme Complexes; Muscle Proteins; Muscle, Skeletal; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Transcription, Genetic; Ubiquitins | 1998 |
Protection from cadmium cytotoxicity by N-acetylcysteine in LLC-PK1 cells.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cadmium; Cell Survival; Dactinomycin; Glutathione; Kidney; LLC-PK1 Cells; Proto-Oncogene Proteins c-fos; Swine | 1998 |
Upregulation of vascular endothelial growth factor by H2O2 in rat heart endothelial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Northern; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelial Growth Factors; Endothelium, Vascular; Gene Expression Regulation; Heart; Hydrogen Peroxide; Kinetics; Lymphokines; Protein Kinase Inhibitors; Protein Kinases; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Proteasome activation as a critical event of thymocyte apoptosis.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Caspase Inhibitors; Caspases; Catalase; Cells, Cultured; Cysteine Endopeptidases; Dactinomycin; Dexamethasone; Enzyme Activation; Etoposide; fas Receptor; Female; Mice; Mice, Inbred BALB C; Mitochondria; Multienzyme Complexes; Proteasome Endopeptidase Complex; T-Lymphocytes | 2000 |
Electronegative LDL from normolipemic subjects induces IL-8 and monocyte chemotactic protein secretion by human endothelial cells.
Topics: Acetylcysteine; Adult; Antioxidants; Cells, Cultured; Chemokine CCL2; Chromatography, Ion Exchange; Dactinomycin; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Female; Free Radical Scavengers; Humans; Interleukin-8; Lipoproteins, LDL; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Thiobarbiturates; Tumor Necrosis Factor-alpha | 2000 |
Lactacystin stimulates arachidonic acid metabolism in rat liver cells: effects of cell density on arachidonic acid release, PGI2 production and cyclooxygenase activity.
Topics: Acetylcysteine; Animals; Arachidonic Acid; Cell Count; Cells, Cultured; Contact Inhibition; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Epoprostenol; Hepatocytes; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Prostaglandin-Endoperoxide Synthases; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 2000 |
Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins | 2001 |
Long term regulation of aquaporin-2 expression in vasopressin-responsive renal collecting duct principal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcysteine; Animals; Aquaporin 2; Aquaporin 6; Aquaporins; Blotting, Western; Cell Line; Cells, Cultured; Colforsin; Cysteine Endopeptidases; Dactinomycin; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Gene Expression Regulation; Kidney Tubules, Collecting; Lysosomes; Mice; Microscopy, Fluorescence; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; Rats; Ribonucleases; RNA, Messenger; RNA, Ribosomal, 18S; Time Factors; Vasopressins | 2002 |
Induction of GADD gene expression by phenethylisothiocyanate in human colon adenocarcinoma cells.
Topics: Acetylcysteine; Adenocarcinoma; Anticarcinogenic Agents; Antigens, Differentiation; Apoptosis; CCAAT-Enhancer-Binding Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Size; Colonic Neoplasms; Dactinomycin; DNA Damage; GADD45 Proteins; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Array Sequence Analysis; Protein Phosphatase 1; Proteins; RNA, Messenger; Transcription Factor CHOP; Transcription Factors; Transcriptional Activation; Tumor Suppressor Protein p53 | 2003 |
Cytoprotective effects of heme oxygenase-1 induction by 3-O-caffeoyl-1-methylquinic acid.
Topics: Acetylcysteine; Animals; Antioxidants; Cattle; Cell Line; Cryoprotective Agents; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Ferritins; Flow Cytometry; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxybenzoates; Molecular Structure; Necrosis; Protoporphyrins; Quinic Acid; Reactive Oxygen Species; RNA, Messenger; tert-Butylhydroperoxide; Time Factors; Up-Regulation | 2004 |
The cell cycle related apoptotic susceptibility to arsenic trioxide is associated with the level of reactive oxygen species.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Catalase; Cell Cycle; Cell Division; Cell Line, Tumor; Dactinomycin; Flow Cytometry; Fluoresceins; Humans; In Situ Nick-End Labeling; Interphase; Naphthoquinones; Oxides; Propidium; Reactive Oxygen Species | 2004 |
Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.
Topics: Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Nucleus; Chromones; Cobalt; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Models, Biological; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Plasmids; Potassium Chloride; Rabbits; Reactive Oxygen Species; Time Factors; Trachea; Transcription Factors; Transcription, Genetic; Transfection; Wortmannin | 2004 |
Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells.
Topics: Acetylcysteine; Acrolein; Antioxidants; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelial Cells; Enzyme Induction; Enzyme Inhibitors; Humans; Oxidative Stress; RNA, Messenger; Thioredoxin-Disulfide Reductase; Umbilical Veins | 2005 |
Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress.
Topics: Acetylcysteine; Alternative Splicing; Animals; Base Sequence; Cell Line; Cell Nucleolus; Cell Nucleus; Chickens; Cysteine Proteinase Inhibitors; Cytoplasm; Dactinomycin; DNA-Binding Proteins; Exons; Gene Deletion; Heat-Shock Response; Humans; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Proteasome Inhibitors; Protein Isoforms; Protein Structure, Tertiary; RNA, Messenger; Transcription, Genetic | 2007 |
Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts.
Topics: Acetylcysteine; Antimetabolites; Biomarkers; Buthionine Sulfoximine; Carcinogens, Environmental; Chromium; Dactinomycin; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation, Enzymologic; Glutathione; Heme Oxygenase-1; Humans; Microarray Analysis; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Skin | 2008 |
Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.
Topics: Acetylcysteine; Blotting, Northern; Cell Line, Tumor; Cycloheximide; Dactinomycin; Ethanol; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; Neoplasm Metastasis; Ovarian Neoplasms; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Biosynthesis | 2008 |
Transcriptional and posttranscriptional regulation of the CTNS gene.
Topics: Acetylcysteine; Amino Acid Transport Systems, Neutral; Cell Culture Techniques; Cell Line; Chromatography, High Pressure Liquid; Cystine; Dactinomycin; DNA Primers; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Genetic Vectors; Humans; Luciferases; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Sulfhydryl Compounds; Transfection | 2011 |
Effects of proteasome inhibitors on the nucleolar size of porcine oocytes.
Topics: Acetylcysteine; Alpha-Amanitin; Animals; Cell Nucleolus; Cysteine Proteinase Inhibitors; Dactinomycin; Female; Leupeptins; Nuclear Proteins; Oocytes; Proteasome Inhibitors; Swine | 2012 |
Anesthetic Isoflurane Induces DNA Damage Through Oxidative Stress and p53 Pathway.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Benzothiazoles; Brain; Caspase 3; Cell Line, Tumor; Cytosol; Dactinomycin; Deoxyribonucleases; DNA Damage; Enzyme Activation; Histones; Humans; Isoflurane; Mice; Models, Biological; Oligopeptides; Oxidative Stress; Signal Transduction; Toluene; Tumor Suppressor Protein p53 | 2017 |