acetylcysteine and cyclic gmp

acetylcysteine has been researched along with cyclic gmp in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19907 (15.91)18.7374
1990's18 (40.91)18.2507
2000's14 (31.82)29.6817
2010's4 (9.09)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Goldschmidt, JE; Tallarida, RJ1
Kameda, M; Katoh, K; Kobayashi, K; Sawada, S; Shirai, K; Takada, O; Toyoda, T; Uno, M; Yamagami, M; Yamamoto, K1
Lawson, DL; Mehta, JL; Mehta, P; Nichols, WW1
George, D; Loscalzo, J; Mendelsohn, ME; O'Neill, S1
Ignarro, LJ; Wood, KS1
Holzmann, S; Kukovetz, WR1
Amarante, P; Andon, N; Cooke, JP; Davies, PF; Loscalzo, J; Mendelsohn, ME; Smick, D; Stamler, J1
Hawlicek, J; Kalenbach, M; Kirsten, N; Kober, G; Krause, A; Satter, P; Schneider, W; von Loh, D; Weyenmeyer, T1
Flaherty, JT1
Balcerzak, SP; Fertel, RH; Magorien, RD; O'Dorisio, MS; Unverferth, DV1
Dunn, JA; Greenberg, RN; Guerrant, RL1
Castresana, MR; Jollow, DJ; McDonald, MH; Newman, WH; Zhang, LM1
Francis, S; Jaraki, O; Loscalzo, J; Stamler, JS; Strauss, WE1
Cobb, JP; Corriveau, CC; Danner, RL; Madara, PJ; Tropea, MM; Van Dervort, AL; Wesley, RA; Yan, L1
Pistelli, A; Salvemini, D; Vane, J1
Harrison, P; Wendon, J; Williams, R1
Farinelli, SE; Greene, LA; Park, DS; Stefanis, L; Yan, CY1
Haught, WH; Lawson, DL; Mehta, JL; Mehta, P1
Barnard, MR; Benoit, SE; Breckwoldt, WL; Furman, MI; Loscalzo, J; Michelson, AD; Rohrer, MJ1
Corriveau, CC; Danner, RL; Madara, PJ; Tropea, MM; Van Dervort, AL; Wesley, RA1
de Koster, BM; Elferink, JG1
Balligand, JL; Joe, EK; Kelly, RA; Longrois, D; Mäki, T; Schussheim, AE; Smith, TW1
Imai, S; Ishibashi, T; Kitagawa, T1
Kleschyov, AL; Malblanc, S; Muller, B; Stoclet, JC1
Brüne, B; Callsen, D; Pfeilschifter, J1
Boudjema, K; Hatakeyama, T; Jaeck, D; Kigawa, G; Kitamura, N; Kumada, K; Nagasaki, H; Nakano, H; Takeuchi, S; Yamaguchi, M1
Chen, Q; Gole, M; Gow, AJ; Ischiropoulos, H; Lee, VM; Themistocleous, M1
Baliga, R; Fishman, MC; Han, X; Huang, P; Kelly, RA; Kubota, I; Michel, T; Opel, DJ; Shannon, RP; Zhao, YY1
Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Russo, I; Trovati, M1
de Oliveira, MG; Krieger, MH; Ricardo, KF; Shishido, SM1
Chang, CH; Chang, GD; Che, D; Chen, ZJ; Liu, S; Vetter, M1
Anfossi, G; Massucco, P; Mattiello, L; Russo, I; Trovati, M1
Alencar, JL; Chalupsky, K; Muller, B; Sarr, M; Schini-Kerth, V; Stoclet, JC; Vanin, AF1
Diallo, AS; Lobysheva, I; Muller, B; Sarr, M; Schini-Kerth, VB; Stoclet, JC1
Bal-Price, A; Brown, GC; Gartlon, J1
Losano, G; Mancardi, D; Pagliaro, P; Penna, C; Rastaldo, R1
de Crom, R; de Waard, MC; Duncker, DJ; Merkus, D; van Deel, ED; van Haperen, R1
Chen, YR; Guo, R; Jiang, DJ; Li, YJ; Nie, SD; Shan, W; Shi, RZ; Zhang, Z; Zhou, Z1
Bai, YP; Chen, YR; Jiang, DJ; Li, YJ; Shi, RZ; Tang, ZY; Xiao, HB; Zhang, GG1
Desai, KM; Dhar, A; Dhar, I; Wu, L1
Barthwal, MK; Boruah, JJ; Das, SP; Dikshit, M; Islam, NS; Jain, M; Kalita, D; Khanna, V; Ramasarma, T1
Antunes, E; Casarin, AL; Lopes-Pires, ME; Marcondes, S; Morganti, RP1
Bhunia, AK; Burnett, AL; Karakus, S; Musicki, B1
Blair, IA; Devoto, M; Escobar-Zarate, D; Estrada, MA; Gillespie, K; Loomes, KM; Lorent, K; Mesaros, C; Pack, M; Rajagopalan, R; Spinner, NB; Winkler, JD; Zhao, X1

Other Studies

44 other study(ies) available for acetylcysteine and cyclic gmp

ArticleYear
Pharmacological evidence that captopril possesses an endothelium-mediated component of vasodilation: effect of sulfhydryl groups on endothelium-derived relaxing factor.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3

    Topics: Acetylcholine; Acetylcysteine; Animals; Captopril; Cyclic GMP; Enalaprilat; Endothelium, Vascular; Glutathione; In Vitro Techniques; Nitric Oxide; Norepinephrine; Pyrogallol; Rabbits; Structure-Activity Relationship; Sulfhydryl Compounds; Superoxide Dismutase; Tiopronin; Vasodilation

1991
Effect of cyclic GMP and sulfhydryl on prostacyclin production by human vascular endothelial cells.
    Japanese circulation journal, 1991, Volume: 55, Issue:6

    Topics: Acetylcysteine; Calcium; Captopril; Cyclic GMP; Cytosol; Endothelium, Vascular; Epoprostenol; Glutathione; Humans; Sulfhydryl Compounds

1991
Captopril-induced reversal of nitroglycerin tolerance: role of sulfhydryl group vs. ACE-inhibitory activity.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:3

    Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Captopril; Cyclic GMP; Drug Tolerance; Enalaprilat; Nitroglycerin; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vasodilation

1991
Inhibition of fibrinogen binding to human platelets by S-nitroso-N-acetylcysteine.
    The Journal of biological chemistry, 1990, Nov-05, Volume: 265, Issue:31

    Topics: Acetylcysteine; Adenosine Diphosphate; Blood Platelets; Cyclic GMP; Fibrinogen; Humans; In Vitro Techniques; Kinetics; Platelet Aggregation; Platelet Aggregation Inhibitors

1990
Hepatic cyclic GMP formation is regulated by similar factors that modulate activation of purified hepatic soluble guanylate cyclase.
    The Journal of biological chemistry, 1987, Apr-15, Volume: 262, Issue:11

    Topics: 1-Methyl-3-isobutylxanthine; Acetaminophen; Acetylcysteine; Animals; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Heme; Liver; Methylnitronitrosoguanidine; Mice; Nitroglycerin; Penicillamine; Phenobarbital; Phenylhydrazines; Potassium Cyanide; Probenecid; Protoporphyrins; Purinones; S-Nitroso-N-Acetylpenicillamine

1987
Cyclic GMP in nicorandil-induced vasodilatation and tolerance development.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Acetylcysteine; Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents

1987
N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor.
    Circulation research, 1989, Volume: 65, Issue:3

    Topics: Acetylcysteine; Animals; Biological Factors; Blood Platelets; Cattle; Cell Survival; Cells, Cultured; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Humans; In Vitro Techniques; Kinetics; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors

1989
[Isolated human venous segments as a model for the study of problems of nitrate tolerance].
    Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 2

    Topics: Acetylcysteine; Coronary Artery Bypass; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Isosorbide Dinitrate; Muscle, Smooth, Vascular; Nitroglycerin; Saphenous Vein; Vascular Resistance; Vasodilation

1989
Hemodynamic attenuation and the nitrate-free interval: alternative dosing strategies for transdermal nitroglycerin.
    The American journal of cardiology, 1985, Dec-27, Volume: 56, Issue:17

    Topics: Acetylcysteine; Administration, Oral; Administration, Topical; Angina Pectoris; Angina, Unstable; Animals; Blood Vessels; Cheek; Cyclic GMP; Drug Administration Schedule; Drug Tolerance; Electrocardiography; Endothelium; Exercise Test; Hemodynamics; Humans; Infusions, Parenteral; Isosorbide Dinitrate; Nitroglycerin; Prostaglandins; Vascular Resistance

1985
N-acetylcysteine prevents the doxorubicin-induced decrease of cyclic GMP.
    Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1

    Topics: Acetylcysteine; Adult; Aged; Biopsy; Cyclic AMP; Cyclic GMP; Doxorubicin; Drug Evaluation; Drug Interactions; Electrocardiography; Guanylate Cyclase; Humans; Middle Aged; Myocardium; Random Allocation; Time Factors

1983
Reduction of the secretory response to Escherichia coli heat-stable enterotoxin by thiol and disulfide compounds.
    Infection and immunity, 1983, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Bacterial Toxins; Body Fluids; Cyclic GMP; Cystamine; Cystathionine; Cysteamine; Cysteine; Cystine; Disulfides; Enterotoxins; Enzyme Activation; Escherichia coli Proteins; Guanylate Cyclase; Intestinal Mucosa; Mice; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1983
Tolerance to nitroglycerin in vascular smooth muscle cells is not affected by the level of intracellular glutathione or L-cysteine.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:6

    Topics: Acetylcysteine; Animals; Cyclic GMP; Cysteine; Cytoplasm; Drug Tolerance; Free Radical Scavengers; Glutathione; Muscle, Smooth, Vascular; Nitroglycerin; Sulfhydryl Reagents; Swine; Vasodilator Agents

1995
Antiplatelet effects of a novel antianginal agent, nicorandil.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:1

    Topics: Acetylcysteine; Adenosine Diphosphate; Analysis of Variance; Binding Sites; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Fibrinogen; Guanylate Cyclase; Humans; Niacinamide; Nicorandil; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Channels; Radioimmunoassay; Vasodilator Agents

1994
Nitric oxide regulates endotoxin-induced TNF-alpha production by human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Apr-15, Volume: 152, Issue:8

    Topics: Acetylcysteine; Cyclic GMP; Gene Expression; Humans; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Macrophages; Neutrophils; Nitric Oxide; Nitroprusside; RNA, Messenger; Tumor Necrosis Factor-alpha

1994
Conversion of glyceryl trinitrate to nitric oxide in tolerant and non-tolerant smooth muscle and endothelial cells.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Acetylcysteine; Animals; Aorta, Thoracic; Cyclic GMP; Endothelium, Vascular; Humans; In Vitro Techniques; Male; Metyrapone; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors; Proadifen; Rabbits; Sulfobromophthalein

1993
Evidence of increased guanylate cyclase activation by acetylcysteine in fulminant hepatic failure.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:5

    Topics: Acetylcysteine; Adolescent; Adult; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Guanylate Cyclase; Hemodynamics; Hepatic Encephalopathy; Humans; Male; Middle Aged; Nitric Oxide; Oxygen; Oxygen Consumption

1996
Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells.
    The Journal of biological chemistry, 1996, Sep-06, Volume: 271, Issue:36

    Topics: Acetylcysteine; Animals; Apoptosis; Apoptosis Regulatory Proteins; Aurintricarboxylic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Caspase 1; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cysteine Endopeptidases; Dactinomycin; Deferoxamine; Enzyme Activation; Humans; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Nerve Growth Factors; PC12 Cells; Rats; RNA; Serpins; Viral Proteins

1996
Studies of vascular tolerance to nitroglycerin: effects of N-acetylcysteine, NG-monomethyl L-arginine, and endothelin-1.
    Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:3

    Topics: Acetylcysteine; Animals; Aorta; Cyclic GMP; Drug Tolerance; Endothelin-1; Enzyme Inhibitors; Free Radical Scavengers; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Rats; Vasodilator Agents

1996
Effects of nitric oxide/EDRF on platelet surface glycoproteins.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 2

    Topics: Acetylcysteine; Adult; Antigens, CD; Cyclic GMP; Flow Cytometry; Humans; Nitric Oxide; P-Selectin; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Tetraspanin 30

1996
Effects of nitric oxide on chemotaxis and endotoxin-induced interleukin-8 production in human neutrophils.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:1

    Topics: Acetylcysteine; Cells, Cultured; Chemotaxis; Complement C5a; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Ferricyanides; Glutathione; Humans; Interleukin-8; Leukotriene B4; Lipopolysaccharides; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Nitroso Compounds; omega-N-Methylarginine; RNA, Messenger; S-Nitrosoglutathione; Up-Regulation

1998
N-acetylcysteine causes a transient stimulation of neutrophil migration.
    Immunopharmacology, 1998, Volume: 38, Issue:3

    Topics: Acetylcysteine; Animals; Calcium; Cell Movement; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Cysteine; Free Radical Scavengers; Guanylate Cyclase; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Rabbits

1998
Regulation of cardiac myocyte contractile function by inducible nitric oxide synthase (iNOS): mechanisms of contractile depression by nitric oxide.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcysteine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Culture Media, Conditioned; Cyclic AMP; Cyclic GMP; Enzyme Induction; GTP-Binding Proteins; In Vitro Techniques; Isoproterenol; Lipopolysaccharides; Macrophages, Alveolar; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley

1998
Diverse relaxation responses of canine large and small conductive coronary arteries to glyceryl trinitrate and nitric oxide on the one hand and to 8-bromoguanosine 3':5' cyclic monophosphate on the other.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: Acetylcysteine; Animals; Biotransformation; Coronary Vessels; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cysteine; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Female; Free Radical Scavengers; Guanylate Cyclase; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Vasodilation; Vasodilator Agents

1998
Nitric oxide-related cyclic GMP-independent relaxing effect of N-acetylcysteine in lipopolysaccharide-treated rat aorta.
    British journal of pharmacology, 1998, Volume: 123, Issue:6

    Topics: Acetylcysteine; Animals; Aorta, Thoracic; Cyclic GMP; In Vitro Techniques; Iron Compounds; Lipopolysaccharides; Male; Muscle Relaxation; Nitric Oxide; Rats; Rats, Wistar

1998
Rapid and delayed p42/p44 mitogen-activated protein kinase activation by nitric oxide: the role of cyclic GMP and tyrosine phosphatase inhibition.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Nov-01, Volume: 161, Issue:9

    Topics: Acetylcysteine; Animals; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic GMP; Enzyme Activation; Free Radical Scavengers; Glomerular Mesangium; Glutathione; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molsidomine; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Onium Compounds; Oxadiazoles; Oxazines; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Rats; S-Nitrosoglutathione; Second Messenger Systems

1998
Improvement of portal flow and hepatic microcirculatory tissue flow with N-acetylcysteine in dogs with obstructive jaundice produced by bile duct ligation.
    The European journal of surgery = Acta chirurgica, 2000, Volume: 166, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Cholestasis; Common Bile Duct; Cyclic GMP; Dogs; Glutathione; Ligation; Liver; Liver Circulation; Male; Microcirculation; Portal Vein; Rats; Rats, Wistar; Regional Blood Flow; Stimulation, Chemical

2000
Two distinct mechanisms of nitric oxide-mediated neuronal cell death show thiol dependency.
    American journal of physiology. Cell physiology, 2000, Volume: 278, Issue:6

    Topics: Acetylcysteine; Animals; Cell Death; Cell Differentiation; Cell Line; Cell Survival; Cyclic GMP; Hydrazines; Molsidomine; Necrosis; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Sulfhydryl Compounds

2000
Increased susceptibility to development of triggered activity in myocytes from mice with targeted disruption of endothelial nitric oxide synthase.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:7

    Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Cells, Cultured; Cyclic GMP; Electrophysiology; Endothelium, Vascular; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Ouabain; Time Factors

2000
N-acetyl-L-cysteine exerts direct anti-aggregating effect on human platelets.
    European journal of clinical investigation, 2001, Volume: 31, Issue:5

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcysteine; Adenosine Diphosphate; Adult; Calcimycin; Cell Membrane Permeability; Collagen; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Humans; Ionomycin; Male; omega-N-Methylarginine; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Quinoxalines

2001
Characterization of the hypotensive effect of S-nitroso-N-acetylcysteine in normotensive and hypertensive conscious rats.
    Nitric oxide : biology and chemistry, 2002, Volume: 7, Issue:1

    Topics: Acetylcysteine; Animals; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Drug Stability; Drug Synergism; Drug Therapy, Combination; Hypertension; Male; Rats; Rats, Wistar; Sulfhydryl Compounds; Vasodilation

2002
Cyclosporin A disrupts bradykinin signaling through superoxide.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Animals; Antioxidants; Blotting, Western; Bradykinin; Cyclic GMP; Cyclosporine; Enzyme Activation; Free Radical Scavengers; GTP-Binding Proteins; Guanylate Cyclase; LLC-PK1 Cells; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Onium Compounds; Phospholipases; Quercetin; Receptor, Bradykinin B2; Receptors, Bradykinin; Signal Transduction; Solubility; Superoxides; Swine; Tyrosine; Vitamin K 3

2003
Platelet resistance to the antiaggregating effect of N-acetyl-L-cysteine in obese, insulin-resistant subjects.
    Thrombosis research, 2003, Apr-15, Volume: 110, Issue:1

    Topics: Acetylcysteine; Adenosine Diphosphate; Adult; Amifostine; Antioxidants; Collagen; Cyclic GMP; Drug Resistance; Female; Free Radical Scavengers; Humans; Insulin Resistance; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Superoxide Dismutase

2003
Inhibition of arterial contraction by dinitrosyl-iron complexes: critical role of the thiol ligand in determining rate of nitric oxide (NO) release and formation of releasable NO stores by S-nitrosation.
    Biochemical pharmacology, 2003, Dec-15, Volume: 66, Issue:12

    Topics: Acetylcysteine; Animals; Arteries; Cyclic GMP; Glutathione; Iron; Male; Mercuric Chloride; Molecular Weight; Nitric Oxide; Nitrogen Oxides; Nitrosation; Rats; Rats, Wistar; S-Nitrosothiols; Sulfhydryl Compounds; Vasoconstriction; Vasodilation

2003
Formation of releasable NO stores by S-nitrosoglutathione in arteries exhibiting tolerance to glyceryl-trinitrate.
    European journal of pharmacology, 2005, Apr-18, Volume: 513, Issue:1-2

    Topics: Acetylcysteine; Analysis of Variance; Animals; Aorta, Thoracic; Cyclic GMP; Diethylamines; Dose-Response Relationship, Drug; Drug Tolerance; In Vitro Techniques; Male; Nitric Oxide; Nitrogen Oxides; Nitroglycerin; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; S-Nitrosoglutathione; Superoxide Dismutase; Thionucleotides; Vasoconstriction; Vasodilation

2005
Nitric oxide stimulates PC12 cell proliferation via cGMP and inhibits at higher concentrations mainly via energy depletion.
    Nitric oxide : biology and chemistry, 2006, Volume: 14, Issue:3

    Topics: Acetylcysteine; Animals; Cell Proliferation; Cell Respiration; Cyclic GMP; Glycolysis; Guanylate Cyclase; Macrophage Activation; Macrophages; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Ornithine Decarboxylase Inhibitors; PC12 Cells; Poly(ADP-ribose) Polymerase Inhibitors; Pyruvic Acid; Rats; Ribonucleotide Reductases; Triazenes; Uridine

2006
Intermittent activation of bradykinin B2 receptors and mitochondrial KATP channels trigger cardiac postconditioning through redox signaling.
    Cardiovascular research, 2007, Jul-01, Volume: 75, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Decanoic Acids; Hydroxy Acids; Mitochondria, Heart; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Perfusion; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Bradykinin B2; Signal Transduction

2007
Vasomotor control in mice overexpressing human endothelial nitric oxide synthase.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcysteine; Animals; Antioxidants; Aorta; Blood Flow Velocity; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic N-Oxides; Cyclic Nucleotide Phosphodiesterases, Type 5; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phosphodiesterase Inhibitors; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Spin Labels; Up-Regulation; Vascular Resistance; Vasodilation; Vasodilator Agents; Vasomotor System

2007
Decrease in endogenous CGRP release in nitroglycerin tolerance: role of ALDH-2.
    European journal of pharmacology, 2007, Sep-24, Volume: 571, Issue:1

    Topics: Acetylcysteine; Aldehyde Dehydrogenase; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Calcitonin Gene-Related Peptide; Captopril; Cell Line; Chloral Hydrate; Cyanamide; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Endothelial Cells; Humans; In Vitro Techniques; Male; Nitric Oxide Donors; Nitroglycerin; Rats; Rats, Wistar; Reactive Oxygen Species; Vasodilation

2007
Involvement of the endothelial DDAH/ADMA pathway in nitroglycerin tolerance: the role of ALDH-2.
    Life sciences, 2008, Mar-26, Volume: 82, Issue:13-14

    Topics: Acetylcysteine; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amidohydrolases; Arginine; Cell Line; Cyclic GMP; Drug Tolerance; Endothelial Cells; Humans; Lipid Peroxides; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroglycerin; Oxidative Stress; Reactive Oxygen Species

2008
Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose.
    British journal of pharmacology, 2010, Volume: 161, Issue:8

    Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Cells, Cultured; Cyclic GMP; Endothelial Cells; Glucose; Guanidines; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Diseases; Vasodilation

2010
Vasomodulatory effect of novel peroxovanadate compounds on rat aorta: Role of rho kinase and nitric oxide/cGMP pathway.
    Pharmacological research, 2011, Volume: 64, Issue:3

    Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Cyclic GMP; Nitric Oxide; Peroxides; Phenylephrine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; rho-Associated Kinases; Vanadates; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2011
Reactive oxygen and nitrogen species modulate the ex-vivo effects of LPS on platelet adhesion to fibrinogen.
    Life sciences, 2011, Nov-21, Volume: 89, Issue:21-22

    Topics: Acetylcysteine; Animals; Blood Platelets; Cyclic GMP; Enzyme Inhibitors; Fibrinogen; Free Radical Scavengers; In Vitro Techniques; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Platelet Adhesiveness; Polyethylene Glycols; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxide Dismutase; Thrombin

2011
S-nitrosylation of NOS pathway mediators in the penis contributes to cavernous nerve injury-induced erectile dysfunction.
    International journal of impotence research, 2018, Volume: 30, Issue:3

    Topics: Acetylcysteine; Animals; Cyclic GMP; Erectile Dysfunction; Male; Nerve Crush; Nitric Oxide; Nitric Oxide Synthase Type III; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Signal Transduction

2018
Impaired Redox and Protein Homeostasis as Risk Factors and Therapeutic Targets in Toxin-Induced Biliary Atresia.
    Gastroenterology, 2020, Volume: 159, Issue:3

    Topics: Acetylcysteine; Animals; Animals, Genetically Modified; Benzodioxoles; Bile Ducts; Biliary Atresia; Cell Line; Cyclic GMP; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Free Radical Scavengers; Glutathione; Humans; Oxidation-Reduction; Proteostasis; Signal Transduction; Zebrafish

2020