acetylcysteine has been researched along with clozapine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 5 (26.32) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Gardner, I; Lai, WG; Uetrecht, JP; Zahid, N | 1 |
| Jian, W; Yao, M; Zhang, D; Zhu, M | 1 |
| Berk, M; Du Preez, JL; Emsley, R; Harvey, BH; Möller, M; Viljoen, FP | 1 |
| Berk, M; Bush, AI; Castle, DJ; Conus, P; Copolov, D; Cuénod, M; Dean, OM; Do, KQ; Mancuso, SG; Rossell, SL | 1 |
| Berk, M; Bozaoglu, K; Castle, DJ; Dark, F; Dean, O; Francis, PS; Galletly, C; Harris, A; Liu, D; Meyer, D; Neill, E; Phillipou, A; Rossell, SL; Sarris, J; Siskind, D | 1 |
| Bolu, A; Çelik, C; Uzun, Ö | 1 |
| Alexandre, J; Chrétien, B; Dolladille, C; Fedrizzi, S; Lelong-Boulouard, V; Sassier, M | 1 |
| Beitler, JR; Dzierba, AL; Furfaro, D; Muir, J; Shah, J | 1 |
| Berk, M; Bozaoglu, K; Castle, DJ; Dark, F; Dean, OM; Francis, PS; Galletly, C; Harris, A; Liu, D; Meyer, D; Neill, E; Phillipou, A; Rossell, SL; Sarris, J; Siskind, D; Yolland, C | 1 |
| Andrade, C | 1 |
3 review(s) available for acetylcysteine and clozapine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Use of N-Acetylcysteine for Clozapine-Induced Acute Liver Injury: A Case Report and Literature Review.
Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Clozapine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Liver Failure, Acute; Middle Aged | 2023 |
Antipsychotic Augmentation With N-Acetylcysteine for Patients With Schizophrenia.
Topics: Acetylcysteine; Antipsychotic Agents; Clozapine; Humans; Schizophrenia | 2022 |
2 trial(s) available for acetylcysteine and clozapine
| Article | Year |
|---|---|
N-acetylcysteine (NAC) in schizophrenia resistant to clozapine: a double blind randomised placebo controlled trial targeting negative symptoms.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Antipsychotic Agents; Australia; Clozapine; Double-Blind Method; Drug Resistance; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Male; Middle Aged; New Zealand; Quality of Life; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult | 2016 |
N-Acetylcysteine (NAC) in Schizophrenia Resistant to Clozapine: A Double-Blind, Randomized, Placebo-Controlled Trial Targeting Negative Symptoms.
Topics: Acetylcysteine; Antipsychotic Agents; Australia; Clozapine; Double-Blind Method; Humans; Quality of Life; Schizophrenia; Treatment Outcome | 2022 |
14 other study(ies) available for acetylcysteine and clozapine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Bioactivation and covalent binding of hydroxyfluperlapine in human neutrophils: implications for fluperlapine-induced agranulocytosis.
Topics: Acetylcysteine; Agranulocytosis; Binding, Competitive; Clozapine; Dibenzazepines; Glutathione; Hemocyanins; Humans; Hypochlorous Acid; Immune Sera; Immunoblotting; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Binding | 2000 |
Rapid detection and characterization of in vitro and urinary N-acetyl-L-cysteine conjugates using quadrupole-linear ion trap mass spectrometry and polarity switching.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chromatography, High Pressure Liquid; Clozapine; Diclofenac; Glutathione; Humans; Microsomes, Liver; Rats; Tandem Mass Spectrometry | 2009 |
Social isolation rearing induces mitochondrial, immunological, neurochemical and behavioural deficits in rats, and is reversed by clozapine or N-acetyl cysteine.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antipsychotic Agents; Behavior, Animal; Brain; Clozapine; Dopamine; Free Radical Scavengers; Kynurenine; Male; Maternal Deprivation; Memory; Mitochondria; Oxidative Stress; Rats; Rats, Sprague-Dawley; Social Behavior; Social Isolation | 2013 |
Benefits of adjunctive N-acetylcysteine in a sub-group of clozapine-treated individuals diagnosed with schizophrenia.
Topics: Acetylcysteine; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Schizophrenia; Treatment Outcome | 2015 |
Effect of N-acetylcysteine on clozapine-induced sialorrhea in schizophrenic patients: a case series.
Topics: Acetylcysteine; Adult; Clozapine; Female; Humans; Male; Middle Aged; Schizophrenia; Sialorrhea | 2020 |
Could N-acetylcysteine improve the safety of clozapine?
Topics: Acetylcysteine; Antipsychotic Agents; Clozapine; Humans; Schizophrenia; Schizophrenia, Treatment-Resistant | 2021 |