acetylcysteine and cimetidine

acetylcysteine has been researched along with cimetidine in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (32.35)	18.7374
1990's	8 (23.53)	18.2507
2000's	8 (23.53)	29.6817
2010's	6 (17.65)	24.3611
2020's	1 (2.94)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Burkhart, KK; Donovan, JW	1
Lewis, RK; Paloucek, FP	1
Marcuard, SP; Rolband, GC	1
Birkett, DJ; Lelo, A; Miners, JO	1
Eddy, AC; Kalhorn, TF; Kharasch, ED; McRorie, TI; Reynolds, R; Slattery, JT	1
Frank, N; Sato, S; Tsuda, M	1
Donovan, JW	1
Davis, M	1
Maldonado, AL; Mitchell, MC; Speeg, KV	1
Litovitz, TL	1
Alphin, RS; Callaham, EM; Foxwell, MH; Smith, WL; Yanni, JM	1
Tams, TR	1
Jackson, JE	1
Ruffalo, RL; Thompson, JF	1
Galinsky, RE; Kaysen, GA; Levy, G; Menke, DJ; Pond, SM; Roberts, SM; Tong, TG	1
Abdul-Cader, Z; Al-Ali, AK; Al-Mustafa, ZH; Qaw, FS	1
Borzone, S; Caglieris, S; Ghia, M; Giannini, E; Mattioli, F; Mereto, E; Risso, D; Testa, R	1
Krenzelok, EP; Zed, PJ	1
Adamicova, K; Franova, S; Nosalova, G; Strapkova, A	1
Bakos, A; Hazai, E; Monostory, K; Vereczkey, L; Zacher, G	1
Betten, DP; Clark, RF; Favata, M; Hernandez, M; Richardson, WH; Riffenburgh, RH; Tanen, DA; Tong, TC	1
Gallo, K; Mainra, R; Moist, L	1
Chang, CY; Martin, P; Tan, HH	1
Galanopoulou, P; Giannioti, K; Liapi, C; Mikros, E; Papalois, A; Theocharis, S; Zira, A	1
Katsuda, H; Katsura, H; Miyamoto, K; Nagata, N; Sai, Y; Waki, Y; Yamashita, M; Yu, J	1
Freeman, WE; Mullins, ME; Yeager, LH	1

Reviews

7 review(s) available for acetylcysteine and cimetidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Assessment and treatment of acetaminophen overdose. Clinical pharmacy, 1991, Volume: 10, Issue:10 Topics: Acetaminophen; Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Drug Overdose; Gastric Lavage; Humans; Ipecac	1991
Protective agents for acetaminophen overdose. Seminars in liver disease, 1986, Volume: 6, Issue:2 Topics: Acetaminophen; Acetylcysteine; Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cimetidine; Cysteamine; Glucuronates; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxides; Liver; Methionine; Necrosis; Propylthiouracil	1986
The anecdotal antidotes. Emergency medicine clinics of North America, 1984, Volume: 2, Issue:1 Topics: Acetylcysteine; Adult; Aged; Animals; Antidotes; Child; Cimetidine; Female; Ferrocyanides; Folic Acid; Heart Diseases; Humans; Magnesium; Male; Middle Aged; Naloxone; Niacinamide; Physostigmine; Poisoning; Pyridoxine; Thioctic Acid	1984
Treatment of acetaminophen overdose. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Jun-01, Volume: 56, Issue:11 Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Anti-Ulcer Agents; Antidotes; Charcoal; Child; Cimetidine; Drug Overdose; Female; Humans; Pregnancy; Time Factors	1999
[About paracetamol again]. Orvosi hetilap, 2001, Feb-18, Volume: 142, Issue:7 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Cimetidine; Drug Overdose; Humans; Liver; Liver Failure, Acute	2001
Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review. Clinical toxicology (Philadelphia, Pa.), 2020, Volume: 58, Issue:12 Topics: Acetaminophen; Acetylcysteine; Acidosis; Animals; Antidotes; Cimetidine; Drug Overdose; Edetic Acid; Fomepizole; Humans; Mitochondria; Pyridoxal Phosphate	2020

Other Studies

27 other study(ies) available for acetylcysteine and cimetidine

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
N-acetylcysteine in treatment of acetaminophen overdose. Journal of clinical gastroenterology, 1992, Volume: 15, Issue:2 Topics: Acetaminophen; Acetylcysteine; Cimetidine; Drug Overdose; Drug Therapy, Combination; Humans	1992
Cimetidine in the treatment of acetaminophen overdose. Journal of clinical gastroenterology, 1991, Volume: 13, Issue:1 Topics: Acetaminophen; Acetylcysteine; Adult; Cimetidine; Drug Overdose; Drug Therapy, Combination; Female; Humans	1991
Mechanism of formation of 6-amino-5-(N-methylformylamino)-1-methyluracil and 3,7-dimethyluric acid from theobromine in the rat in vitro: involvement of cytochrome P-450 and a cellular thiol. Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:8 Topics: Acetylcysteine; Animals; Cimetidine; Cysteine; Cytochrome P-450 Enzyme System; Dithiothreitol; Glutathione; Kinetics; Male; Metyrapone; Microsomes, Liver; Pyridines; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Theobromine; Uracil; Uric Acid	1990
Lack of effect of cimetidine on acetaminophen disposition in humans. Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:5 Topics: Acetaminophen; Acetylcysteine; Adult; Cimetidine; Female; Glutathione; Humans; Least-Squares Analysis; Liver; Male	1989
pH-dependent degradation of nitrosocimetidine and its mechanisms. Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:10 Topics: Acetylcysteine; Cimetidine; Hydrogen-Ion Concentration; Mutagens	1988
Hepatotoxic and hepatoprotective potential of histamine (H2)-receptor antagonists. The American journal of medicine, 1988, Volume: 85, Issue:6 Topics: Acetaminophen; Acetylcysteine; Animals; Cimetidine; Humans; Liver	1988
Additive protection of cimetidine and N-acetylcysteine treatment against acetaminophen-induced hepatic necrosis in the rat. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3 Topics: Acetaminophen; Acetylcysteine; Animals; Benzoquinones; Cimetidine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Imines; Liver; Male; Necrosis; Rats; Rats, Inbred F344	1985
A method for measuring changes in tracheal mucus gel layer thickness as an indication of an immediate hypersensitivity response. International archives of allergy and applied immunology, 1984, Volume: 74, Issue:4 Topics: Acetylcysteine; Aluminum Hydroxide; Animals; Atropine; Chromones; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Immunologic; Expectorants; Hypersensitivity, Immediate; Immune Sera; Methods; Methysergide; Mucus; Ovalbumin; Pyrilamine; Rats; Rats, Inbred Strains; Trachea	1984
Management of liver disease in dogs and cats. Modern veterinary practice, 1984, Volume: 65, Issue:2 Topics: Acetylcysteine; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Bacterial Infections; Cat Diseases; Cats; Cimetidine; Diuretics; Dog Diseases; Dogs; Lactulose; Liver Diseases; Prednisolone	1984
Cimetidine protects against acetaminophen toxicity. Life sciences, 1982, Jul-05, Volume: 31, Issue:1 Topics: Acetaminophen; Acetylcysteine; Adolescent; Animals; Cimetidine; Female; Guanidines; Humans; Liver; Male; Mice; Mice, Inbred Strains	1982
Cimetidine and acetylcysteine as antidote for acetaminophen overdose. Southern medical journal, 1982, Volume: 75, Issue:8 Topics: Acetaminophen; Acetylcysteine; Antidotes; Chemical and Drug Induced Liver Injury; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Drug Therapy, Combination; Guanidines; Humans; Liver Diseases; Time Factors	1982
Massive intoxication with acetaminophen and propoxyphene: unexpected survival and unusual pharmacokinetics of acetaminophen. Journal of toxicology. Clinical toxicology, 1982, Volume: 19, Issue:1 Topics: Acetaminophen; Acetylcysteine; Adult; Animals; Cimetidine; Dextropropoxyphene; Female; Humans; Kinetics; Lethal Dose 50; Male; Mice; Renal Dialysis; Time Factors	1982
Cimetidine enhances the hepatoprotective action of N-acetylcysteine in mice treated with toxic doses of paracetamol. Toxicology, 1997, Sep-05, Volume: 121, Issue:3 Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Cimetidine; Free Radical Scavengers; Glutathione; Histamine H2 Antagonists; Liver; Liver Diseases; Male; Mice; Microsomes, Liver; Necrosis; Survival Rate	1997
Effects of reduced glutathione and n-acetylcysteine on lidocaine metabolism in cimetidine treated rats. Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2 Topics: Acetylcysteine; Anesthetics, Local; Animals; Cimetidine; Drug Interactions; Fluorescence Polarization Immunoassay; Free Radical Scavengers; Glutathione; Histamine H2 Antagonists; Injections, Intraperitoneal; Lidocaine; Rats; Rats, Sprague-Dawley; Time Factors	1998
[Mechanisms of the effect of oxidants on the respiratory system]. Bratislavske lekarske listy, 1999, Volume: 100, Issue:10 Topics: Acetylcysteine; Animals; Cimetidine; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Free Radical Scavengers; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Naproxen; Oxidants; Toluene; Trachea	1999
Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model. Annals of emergency medicine, 2007, Volume: 50, Issue:3 Topics: Acetylcysteine; Alanine Transaminase; Amanitins; Animals; Antidotes; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cimetidine; Disease Models, Animal; Male; Mice; Mushroom Poisoning; Penicillin G; Random Allocation; Silybin; Silymarin; Thioctic Acid	2007
Effect of N-acetylcysteine on renal function in patients with chronic kidney disease. Nephrology (Carlton, Vic.), 2007, Volume: 12, Issue:5 Topics: Acetylcysteine; Aged; Chronic Disease; Cimetidine; Creatinine; Cystatin C; Cystatins; Drug Synergism; Female; Free Radical Scavengers; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Time Factors	2007
Acetaminophen hepatotoxicity: current management. The Mount Sinai journal of medicine, New York, 2009, Volume: 76, Issue:1 Topics: Acetaminophen; Acetylcysteine; Antidotes; Charcoal; Chemical and Drug Induced Liver Injury; Cimetidine; Comorbidity; Disease Progression; Drug and Narcotic Control; Free Radical Scavengers; Humans; Liver Failure; Liver Transplantation; Prognosis; Renal Dialysis; Severity of Illness Index; Treatment Outcome	2009
Acute liver acetaminophen toxicity in rabbits and the use of antidotes: a metabonomic approach in serum. Journal of applied toxicology : JAT, 2009, Volume: 29, Issue:5 Topics: Acetaminophen; Acetylcysteine; Acute Disease; Alanine Transaminase; Animals; Antidotes; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cimetidine; Disease Models, Animal; Liver; Magnetic Resonance Spectroscopy; Male; Rabbits; Silybin; Silymarin	2009
Protecting cisplatin-induced nephrotoxicity with cimetidine does not affect antitumor activity. Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:11 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line; Cell Line, Tumor; Cimetidine; Cisplatin; Infusions, Intravenous; Kidney; Male; Organic Cation Transport Proteins; Osteosarcoma; Platinum; Rats; Rats, Wistar; Reactive Oxygen Species; Renal Agents	2010