acetylcysteine and chromium

acetylcysteine has been researched along with chromium in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.90)18.7374
1990's3 (10.34)18.2507
2000's8 (27.59)29.6817
2010's12 (41.38)24.3611
2020's4 (13.79)2.80

Authors

AuthorsStudies
Endo, A; Watanabe, T1
Banner, W; Capin, DM; Chang, S; Hopf, SB; Koch, M; Tong, TG1
Bagnasco, M; Camoirano, A; De Flora, S; Izzotti, A; Orlando, M1
Dubrovskaya, VA; Wetterhahn, KE1
Hamilton, JW; Liu, KJ; Wetterhahn, KE; Yuann, JM1
Balansky, RM; Camoirano, A; D'Agostini, F; de Flora, S1
Decordier, I; Hantson, P; Haufroid, V; Lison, D; Van Caenegem, O1
Cabilla, JP; Duvilanski, BH; Machiavelli, LI; Poliandri, AH; Quinteros, FA1
Chen, Y; Fu, J; Liang, X; Tang, L; Zhang, N; Zhang, QH1
Chen, Y; Dong, Q; Fu, J; Liang, X; Tang, L; Zhang, QH1
He, Q; Joseph, P; Umbright, C1
Cabilla, JP; Duvilanski, BH; Machiavelli, LI; Miler, EA; Quinteros, FA1
Fang, KM; Tzeng, SF; Wang, CC; Yang, CS1
Chang, HY; Guo, YL; Lee, YH; Pan, MH; Sheu, HM; Wang, BJ; Wang, YJ1
Chen, J; Deng, Y; Liu, X; Xiao, F; Zeng, M; Zhong, C1
Karayakar, F; Karaytug, S; Sevgiler, Y1
Schiestl, RH; Sobol, Z1
Feng, X; Guan, L; Hu, Q; Xiao, F; Zeng, M; Zhong, C1
Luczak, MW; Zhitkovich, A1
Huang, CC; Lee, YH; Lin, CH; Sheu, HM; Su, SB; Tsai, JC; Wang, BJ; Wang, YJ1
Ghazaghi, M; Mousavi, HZ; Shirkhanloo, H1
Boşgelmez, Iİ; Güvendik, G2
Liang, Q; Liu, K; Xiao, F; Xiao, Y; Zeng, M; Zhong, C1
Chen, HY; Cheng, HT; Lu, JX; Seak, CJ; Smollin, C; Yu, JH1
Liang, N; Liang, Y; Lu, C; Ma, Y; Xiao, F; Zhang, Y1
Grulli, F; Locatelli, CA; Lonati, D; Perotti, F; Ronchi, A; Spinillo, A1
He, S; Li, L; Li, W; Li, X; Liu, Y; Yu, X; Zhou, J1
Fu, G; Gao, Y; Huang, H; Jin, L; Kom, MC; Shen, J; Tang, Y; Xie, Y; Yan, J1

Other Studies

29 other study(ies) available for acetylcysteine and chromium

ArticleYear
Analysis of protective activity of N-acetylcysteine against teratogenicity of heavy metals.
    Reproductive toxicology (Elmsford, N.Y.), 1988, Volume: 2, Issue:2

    Topics: Abnormalities, Drug-Induced; Acetylcysteine; Animals; Cadmium Poisoning; Chromium; Drug Synergism; Mercury Poisoning; Mice; Mice, Inbred ICR

1988
Experimental chelation therapy in chromium, lead, and boron intoxication with N-acetylcysteine and other compounds.
    Toxicology and applied pharmacology, 1986, Mar-30, Volume: 83, Issue:1

    Topics: Acetylcysteine; Animals; Boric Acids; Chelating Agents; Chromates; Chromium; Female; Kinetics; Lead; Lead Poisoning; Male; Organometallic Compounds; Potassium Dichromate; Rats; Rats, Inbred Strains; Time Factors

1986
DNA fragmentation, DNA-protein crosslinks, postlabeled nucleotidic modifications, and 8-hydroxy-2'-deoxyguanosine in the lung but not in the liver of rats receiving intratracheal instillations of chromium(VI). Chemoprevention by oral N-acetylcysteine.
    Mutation research, 1998, May-25, Volume: 400, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Administration, Oral; Animals; Antimutagenic Agents; Chromates; Chromium; Deoxyguanosine; DNA; DNA Fragmentation; Intubation, Intratracheal; Liver; Lung; Male; Nucleotides; Phosphorus Radioisotopes; Proteins; Rats; Rats, Sprague-Dawley

1998
Effects of Cr(VI) on the expression of the oxidative stress genes in human lung cells.
    Carcinogenesis, 1998, Volume: 19, Issue:8

    Topics: Acetylcysteine; Actins; Carcinogens, Environmental; Cell Line; Chromium; Glutathione; Heme Oxygenase (Decyclizing); Humans; Lung Neoplasms; Oxidative Stress; Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium-DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of osteogenic disorder shionogi rats following treatment with chromium(VI).
    Carcinogenesis, 1999, Volume: 20, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antimetabolites; Ascorbic Acid; Buthionine Sulfoximine; Chromium; Deoxyguanosine; DNA Adducts; Free Radical Scavengers; Glutathione; Ketones; Kidney; Liver; Oxidation-Reduction; Rats; Rats, Mutant Strains

1999
Interactions between N-acetylcysteine and ascorbic acid in modulating mutagenesis and carcinogenesis.
    International journal of cancer, 2000, Dec-01, Volume: 88, Issue:5

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Carcinogenicity Tests; Cell Transformation, Neoplastic; Chromium; Drug Stability; Female; Lung Neoplasms; Mice; Mutagenesis; Urethane

2000
Hexavalent chromium ingestion: biological markers of nephrotoxicity and genotoxicity.
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adolescent; Ascorbic Acid; beta 2-Microglobulin; Biomarkers; Charcoal; Chromium; Creatinine; Deoxyguanosine; DNA Damage; Female; Humans; Kidney Tubules, Proximal; Oxidation-Reduction; Poisoning; Potassium Dichromate; Retinol-Binding Proteins; Suicide, Attempted

2005
In vivo and in vitro effects of chromium VI on anterior pituitary hormone release and cell viability.
    Toxicology and applied pharmacology, 2007, Jan-01, Volume: 218, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Chromium; Dose-Response Relationship, Drug; Environmental Pollutants; Enzyme Activation; Gonadotropins, Pituitary; Hypothalamus; Liver; Luteinizing Hormone; Male; Membrane Potential, Mitochondrial; Pituitary Gland, Anterior; Potassium Dichromate; Prolactin; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors

2007
[Effect of chromium ion and antioxidant N-acetyl-cysteine on morphology of human osteoblast-like MG63 cell line].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2007, Volume: 38, Issue:3

    Topics: Acetylcysteine; Alloys; Animals; Antioxidants; Cell Line; Chromium; Cytotoxins; Humans; Osteoblasts; Salts; Solutions

2007
Oxidative stress as a component of chromium-induced cytotoxicity in rat calvarial osteoblasts.
    Cell biology and toxicology, 2008, Volume: 24, Issue:3

    Topics: Acetylcysteine; Alkaline Phosphatase; Animals; Chromium; Male; Microscopy, Electron, Transmission; Osteoblasts; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species

2008
Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 103, Issue:2

    Topics: Acetylcysteine; Antimetabolites; Biomarkers; Buthionine Sulfoximine; Carcinogens, Environmental; Chromium; Dactinomycin; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation, Enzymologic; Glutathione; Heme Oxygenase-1; Humans; Microarray Analysis; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Skin

2008
Mechanisms of chromium (VI)-induced apoptosis in anterior pituitary cells.
    Toxicology, 2008, Jul-30, Volume: 249, Issue:2-3

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspases; Catalase; Cells, Cultured; Chromium; DNA Primers; Male; Oxidative Stress; Pituitary Gland, Anterior; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53

2008
Reactive oxygen species-induced cell death of rat primary astrocytes through mitochondria-mediated mechanism.
    Journal of cellular biochemistry, 2009, Aug-01, Volume: 107, Issue:5

    Topics: Acetylcysteine; Animals; Apoptosis Inducing Factor; Astrocytes; Caspase 3; Cell Death; Cell Nucleus; Cells, Cultured; Chromium; Cytoprotection; DNA; Endodeoxyribonucleases; Enzyme Activation; Membrane Potential, Mitochondrial; Mitochondria; Neurons; NF-kappa B; Protein Binding; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transcription Factor AP-1

2009
N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species.
    Experimental dermatology, 2010, Volume: 19, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Chromium; Dermatitis, Allergic Contact; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Female; Glutathione; Guinea Pigs; Hydrogen Peroxide; Malondialdehyde; Reactive Oxygen Species; Severity of Illness Index; Skin

2010
[Antagonistic effect of N-acetylcysteine on apoptosis of L-02 hepatocyte induced by Cr(VI) with or without caspase inhibitor].
    Wei sheng yan jiu = Journal of hygiene research, 2010, Volume: 39, Issue:6

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Carcinogens, Environmental; Caspase Inhibitors; Caspases; Cell Line; Chromium; DNA Damage; Fetus; Hepatocytes; Humans; Oxidative Stress; Reactive Oxygen Species

2010
Comparison of the protective effects of antioxidant compounds in the liver and kidney of Cd- and Cr-exposed common carp.
    Environmental toxicology, 2014, Volume: 29, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Carps; Catalase; Chromium; Curcumin; Glutathione; Kidney; Lipid Peroxidation; Liver; Oxidative Stress; Superoxide Dismutase; Taurine; Thioctic Acid; Water Pollutants, Chemical

2014
Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity.
    Environmental and molecular mutagenesis, 2012, Volume: 53, Issue:2

    Topics: Acetylcysteine; Animals; Carcinogens, Environmental; Cell Line; Chromium; DNA Damage; DNA Repair; Free Radical Scavengers; Homologous Recombination; Mutation Rate; Oxidation-Reduction; Rats

2012
Hexavalent chromium induces energy metabolism disturbance and p53-dependent cell cycle arrest via reactive oxygen species in L-02 hepatocytes.
    Molecular and cellular biochemistry, 2012, Volume: 371, Issue:1-2

    Topics: Acetylcysteine; Benzothiazoles; Carcinogens, Environmental; Cell Cycle Checkpoints; Chromium; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Energy Metabolism; Environmental Pollutants; Hepatocytes; Humans; Reactive Oxygen Species; Signal Transduction; Toluene; Tumor Suppressor Protein p53

2012
Role of direct reactivity with metals in chemoprotection by N-acetylcysteine against chromium(VI), cadmium(II), and cobalt(II).
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Acetylcysteine; Antioxidants; Blotting, Western; Cadmium; Cell Line; Chromium; Cobalt; Cytoprotection; Humans; Oxidative Stress

2013
N-acetylcysteine attenuates hexavalent chromium-induced hypersensitivity through inhibition of cell death, ROS-related signaling and cytokine expression.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Autophagy; Cells, Cultured; Chromium; Dermatitis, Allergic Contact; Drug Evaluation, Preclinical; Female; Gene Expression Regulation; Guinea Pigs; Interleukin-1alpha; Keratinocytes; MAP Kinase Signaling System; NF-kappa B; Oncogene Protein v-akt; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2014
Chromium speciation in human blood samples based on acetyl cysteine by dispersive liquid-liquid biomicroextraction and in-vitro evaluation of acetyl cysteine/cysteine for decreasing of hexavalent chromium concentration.
    Journal of pharmaceutical and biomedical analysis, 2016, Jan-25, Volume: 118

    Topics: Acetylcysteine; Chromium; Cysteine; Drug Evaluation, Preclinical; Environmental Pollutants; Humans; Liquid Phase Microextraction; Prodrugs

2016
N-Acetyl-L-Cysteine Protects Liver and Kidney Against Chromium(VI)-Induced Oxidative Stress in Mice.
    Biological trace element research, 2017, Volume: 178, Issue:1

    Topics: Acetylcysteine; Animals; Chromium; Kidney; Lipid Peroxidation; Liver; Mice; Oxidative Stress

2017
Beneficial Effects of N-Acetyl-L-cysteine or Taurine Pre- or Post-treatments in the Heart, Spleen, Lung, and Testis of Hexavalent Chromium-Exposed Mice.
    Biological trace element research, 2019, Volume: 190, Issue:2

    Topics: Acetylcysteine; Animals; Chromium; Heart; Lipid Peroxidation; Lung; Male; Mice; Spleen; Sulfhydryl Compounds; Taurine; Testis

2019
Cr(VI)-Induced Autophagy Protects L-02 Hepatocytes from Apoptosis Through the ROS-AKT-mTOR Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:4

    Topics: Acetylcysteine; Apoptosis; Autophagy; Cell Line; Chromium; Cytoprotection; Free Radical Scavengers; Hepatocytes; Humans; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases

2018
N-acetylcysteine and ascorbic acid therapy for acute hepatic injury after hexavalent chromium ingestion.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:1

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Chromium; Drug Therapy, Combination; Humans; Male; Middle Aged; Oxidative Stress; Treatment Outcome

2020
Blockage of ROS-ERK-DLP1 signaling and mitochondrial fission alleviates Cr(VI)-induced mitochondrial dysfunction in L02 hepatocytes.
    Ecotoxicology and environmental safety, 2019, Dec-30, Volume: 186

    Topics: Acetylcysteine; Antioxidants; Carcinogens, Environmental; Chromium; Dynamins; Flavonoids; Hepatocytes; Humans; Liver; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Dynamics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Kinase Inhibitors; Reactive Oxygen Species; Signal Transduction

2019
Management of high concentrations of cobalt and chromium in blood due to metal-on-metal hip arthroplasty in a pregnant woman.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:1

    Topics: Abortion, Spontaneous; Acetylcysteine; Adult; Arthroplasty, Replacement, Hip; Chelating Agents; Chromium; Cobalt; Female; Hip Prosthesis; Humans; Live Birth; Maternal Age; Metal-on-Metal Joint Prostheses; Middle Aged; Pregnancy; Pregnancy Complications; Prosthesis Design; Risk Factors; Treatment Outcome; Up-Regulation

2021
Cr (VI) induces abnormalities in glucose and lipid metabolism through ROS/Nrf2 signaling.
    Ecotoxicology and environmental safety, 2021, Volume: 219

    Topics: Acetylcysteine; Animals; Antioxidants; Chromium; Glucose; Insulin; Lipid Metabolism; Mice; NF-E2-Related Factor 2; Reactive Oxygen Species; Signal Transduction

2021
Role of NF-κB signaling pathway in hexavalent chromium-induced hepatotoxicity.
    Environmental toxicology, 2023, Volume: 38, Issue:6

    Topics: Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Chromium; Humans; Mice; Mice, Inbred C57BL; NF-kappa B; Reactive Oxygen Species; Signal Transduction

2023