acetylcysteine has been researched along with chitosan in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (17.14) | 29.6817 |
| 2010's | 17 (48.57) | 24.3611 |
| 2020's | 12 (34.29) | 2.80 |
| Authors | Studies |
|---|---|
| Bernkop-Schnürch, A; Grabovac, V; Hoffer, MH; Palmberger, TF; Schmitz, T | 1 |
| Bernkop-Schnürch, A; Hombach, J; Hoyer, H | 1 |
| Bernkop-Schnürch, A; Hombach, J; Schmitz, T | 1 |
| Li, C; Teng, D; Wang, X; Wang, Z; Wu, Z; Zhang, X; Zheng, C | 1 |
| Chae, JJ; Chuck, RS; Hongyok, T; Li, L; Na, D; Shin, YJ | 1 |
| Dong, RN; Li, CX; Wu, ZM; Yu, DM; Zhang, SM; Zhang, XG; Zheng, C | 1 |
| Baldwin, EA; Narciso, JA; Plotto, A; Rattanapanone, N | 1 |
| Carter, M; Lim, LY; Loh, JW; Saunders, M; Schneider, J | 1 |
| Bai, H; Chen, YY; Hou, Z; Jia, M; Luo, XX; Mao, XG; Meng, JR; Xue, XY; Zhou, Y | 1 |
| Ai, X; Ding, W; Han, X; He, Z; Kou, L; Li, L; Lian, H; Liu, X; Ren, G; Sun, J; Sun, Y; Wang, S; Wang, Y; Wu, C; Zhang, T; Zhang, Y | 1 |
| Ball, RL; Matthew, HW; Miles, KB | 1 |
| Li, J; Liu, D; Pan, W; Tan, G; Yang, X; Zhao, Z | 1 |
| Alqathama, A; Elsaid, N; Elsaid, Z; Jackson, TL; Somavarapu, S | 1 |
| Bai, C; He, F; Li, J; Liu, D; Liu, Z; Pan, H; Wu, Q; Yang, X; Yu, S | 1 |
| Cutrignelli, A; Denora, N; Depalo, N; Fanizza, E; Franco, M; Iacobazzi, RM; Laquintana, V; Lopalco, A; Lopedota, A; Milella, A; Perrone, M | 1 |
| Baumgartner, R; Garhöfer, G; Höller, S; Kaya, S; O'Rourke, M; Peterson, W; Prinz, M; Schmetterer, L; Schmidl, D; Unterhuber, A; Werkmeister, R; Witkowska, KJ; Wolter, A | 1 |
| Cheng, B; Li, J; Liu, D; Pan, H; Wu, Q | 1 |
| Cheng, B; Li, J; Liu, D; Pan, W; Tan, G | 1 |
| Costa, F; Gomes, P; Lamghari, M; Martins, MCL; Parreira, P; Sousa, DM | 1 |
| Dua, HS; Messina, M | 1 |
| Bernkop-Schnürch, A; Cutrignelli, A; Denora, N; Franco, M; Laquintana, V; Lopalco, A; Lopedota, A; Perrone, M | 1 |
| Jindatip, D; Kitkumthorn, N; Mutirangura, A; Nilyai, S; Rojanathanes, R; Sae-Liang, N; Sereemaspun, A; Sooklert, K | 1 |
| Chen, Y; Ding, L; Du, Z; Liu, B; Liu, J; Wu, X; Xiao, H; Zhang, B; Zhang, H; Zhang, T | 1 |
| Hamedinasab, H; Jaafari, MR; Mashreghi, M; Mellat, M; Rezayan, AH | 1 |
| Hoeller, S; Knoetzl, W; Nepp, J; Prinz, A; Prinz, M | 1 |
| Grisoli, P; Guerini, M; Pane, C; Perugini, P | 1 |
| Hu, G; Jin, Z; Zhao, K | 1 |
| Feng, J; Han, J; Hong, W; Li, K; Li, Y; Sheng, Y; Sun, X; Tian, B; Xie, S; Yan, F | 1 |
| Akbari, V; Dehghani, A; Hassanzadeh, F; Mostafavi, SA; Rezazadeh, M; Taheri, SL; Talebi, A | 1 |
| Hwan Shin, D; Jie, G; Kang, JH; Kim, DW; Kim, JY; Kim, S; Kim, YJ; Kwan Kwon, T; Na, SB; Oh, DW; Park, CW; Shin, MS; Sung Kang, K | 1 |
| Abbasifard, A; Asl, SS; Azizi, Z; Firouzian, F; Karbasi, A; Ranjbar, A | 1 |
| Alvandi, H; Hamedinasab, H; Jaafari, MR; Mashreghi, M; Rezayan, AH | 1 |
| Singh, S; Wairkar, S | 1 |
| Bernkop-Schnürch, A; Le-Vinh, B; Matuszczak, B; Nguyen Le, NM; Steinbring, C | 1 |
| Barbugli, PA; Carnero Canales, CS; Caruso, IP; Chorilli, M; Colturato, VMM; da Silva Barud, H; de Lourenço, IO; de Melo, FA; Franzyk, H; Hansen, PR; Pavan, FR; Primo, LMDG; Roque-Borda, CA; Sábio, RM; Vicente, EF | 1 |
1 trial(s) available for acetylcysteine and chitosan
| Article | Year |
|---|---|
A Controlled, Randomized Double-Blind Study to Evaluate the Safety and Efficacy of Chitosan-N-Acetylcysteine for the Treatment of Dry Eye Syndrome.
Topics: Acetylcysteine; Adult; Chitosan; Cohort Studies; Double-Blind Method; Dry Eye Syndromes; Female; Humans; Male; Tears; Tomography, Optical Coherence | 2017 |
34 other study(ies) available for acetylcysteine and chitosan
| Article | Year |
|---|---|
Synthesis and characterization of a chitosan-N-acetyl cysteine conjugate.
Topics: Acetylcysteine; Adsorption; Animals; Chitosan; Hydrogen-Ion Concentration; Intestinal Mucosa; Molecular Structure; Muramidase; Oxidation-Reduction; Rheology; Sulfhydryl Compounds; Swine; Tensile Strength; Viscosity; Water | 2008 |
Thiolated chitosans: development and in vitro evaluation of an oral tobramycin sulphate delivery system.
Topics: Acetylcysteine; Administration, Oral; Animals; Biological Transport; Caco-2 Cells; Chitosan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Epithelial Cells; Glutathione; Humans; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Tablets; Technology, Pharmaceutical; Tobramycin; Verapamil | 2008 |
Chitosan-N-acetyl cysteine conjugates: in vitro evaluation of permeation enhancing and P-glycoprotein inhibiting properties.
Topics: Acetylcysteine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Chitosan; Dextrans; Drug Carriers; Fluoresceins; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Molecular Weight; Permeability; Rats; Rhodamine 123; Toxicity Tests | 2008 |
Chitosan-NAC nanoparticles as a vehicle for nasal absorption enhancement of insulin.
Topics: Acetylcysteine; Administration, Intranasal; Animals; Cell Adhesion; Chitosan; Insulin; Magnetic Resonance Spectroscopy; Models, Chemical; Mucins; Nanoparticles; Polyphosphates; Rats; Spectrophotometry, Infrared; Sulfhydryl Compounds; Surface Properties | 2009 |
Effect of chitosan-N-acetylcysteine conjugate in a mouse model of botulinum toxin B-induced dry eye.
Topics: Acetylcysteine; Administration, Topical; Animals; Blinking; Botulinum Toxins; Botulinum Toxins, Type A; Chitosan; Conjunctiva; Cornea; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Female; Fluorescent Antibody Technique, Indirect; Fluorometholone; Lacrimal Apparatus; Mice; Mice, Inbred CBA; Ophthalmic Solutions; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tears | 2009 |
Disulfide-crosslinked chitosan hydrogel for cell viability and controlled protein release.
Topics: 3T3 Cells; Acetylcysteine; Animals; Cell Adhesion; Cell Survival; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Disulfides; Drug Compounding; Electrophoresis, Polyacrylamide Gel; Hydrogels; Magnetic Resonance Spectroscopy; Mice; Microscopy, Electron, Scanning; Molecular Weight; Proteins; Rheology; Serum Albumin, Bovine; Sulfhydryl Compounds; Thermogravimetry | 2009 |
Surface treatments and coatings to maintain fresh-cut mango quality in storage.
Topics: Acetylcysteine; Ascorbic Acid; Carboxymethylcellulose Sodium; Carrageenan; Chemical Phenomena; Chitosan; Citric Acid; Food Handling; Food Microbiology; Food Preservation; Food Preservatives; Fruit; Humans; Hydrogen-Ion Concentration; Maillard Reaction; Mangifera; Pigmentation; Quality Control; Sensation; Time Factors | 2010 |
Spinning disc processing technology: potential for large-scale manufacture of chitosan nanoparticles.
Topics: Acetaminophen; Acetylcysteine; Chitosan; Microscopy, Electron, Transmission; Nanoparticles; Particle Size | 2010 |
Promoting effects of chemical permeation enhancers on insulin permeation across TR146 cell model of buccal epithelium in vitro.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Adsorption; Cell Line, Tumor; Cell Survival; Cheek; Chitosan; Glutathione; Humans; Insulin; Mouth Mucosa; Nitroprusside; Phosphatidylcholines | 2012 |
Enhanced oral delivery of paclitaxel using acetylcysteine functionalized chitosan-vitamin E succinate nanomicelles based on a mucus bioadhesion and penetration mechanism.
Topics: Acetylcysteine; Animals; Chitosan; Drug Carriers; Micelles; Mucus; Paclitaxel; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Thermogravimetry; Vitamin E | 2013 |
Chitosan films with improved tensile strength and toughness from N-acetyl-cysteine mediated disulfide bonds.
Topics: Acetylcysteine; Chitosan; Crystallization; Disulfides; Elastic Modulus; Hydrogen-Ion Concentration; Tensile Strength; Tissue Engineering | 2016 |
A comparative study on the efficiency of chitosan-N-acetylcysteine, chitosan oligosaccharides or carboxymethyl chitosan surface modified nanostructured lipid carrier for ophthalmic delivery of curcumin.
Topics: Acetylcysteine; Administration, Ophthalmic; Animals; Chitin; Chitosan; Cornea; Curcumin; Drug Carriers; Drug Liberation; Female; Kinetics; Lipids; Male; Nanostructures; Oligosaccharides; Particle Size; Permeability; Rabbits | 2016 |
PLGA Microparticles Entrapping Chitosan-Based Nanoparticles for the Ocular Delivery of Ranibizumab.
Topics: Acetylcysteine; Cell Line; Cell Movement; Cell Survival; Chitosan; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Lactic Acid; Macular Degeneration; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyphosphates; Ranibizumab; Spectroscopy, Fourier Transform Infrared | 2016 |
Potential advantages of a novel chitosan-N-acetylcysteine surface modified nanostructured lipid carrier on the performance of ophthalmic delivery of curcumin.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Cornea; Curcumin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Female; Humans; Lipids; Male; Nanostructures; Ophthalmic Solutions; Particle Size; Rabbits; Surface Properties | 2016 |
Spray-dried mucoadhesives for intravesical drug delivery using N-acetylcysteine- and glutathione-glycol chitosan conjugates.
Topics: Acetylcysteine; Adhesives; Administration, Intravesical; Animals; Chitosan; Chromatography, Gel; Desiccation; Drug Delivery Systems; Glutathione; Microspheres; Molecular Weight; Mucins; Nanoparticles; Nephelometry and Turbidimetry; Photoelectron Spectroscopy; Solubility; Static Electricity; Sulfhydryl Compounds; Sus scrofa | 2016 |
Ex Vivo and in Vivo Evaluation of the Effect of Coating a Coumarin-6-Labeled Nanostructured Lipid Carrier with Chitosan-N-acetylcysteine on Rabbit Ocular Distribution.
Topics: Acetylcysteine; Animals; Chitosan; Cornea; Coumarins; Drug Carriers; Eye; Lipids; Nanoparticles; Nanostructures; Rabbits; Thiazoles | 2017 |
Transport mechanism of chitosan-N-acetylcysteine, chitosan oligosaccharides or carboxymethyl chitosan decorated coumarin-6 loaded nanostructured lipid carriers across the rabbit ocular.
Topics: Acetylcysteine; Administration, Ophthalmic; Animals; Chitosan; Cornea; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Excipients; Lipids; Male; Nanostructures; Oligosaccharides; Ophthalmic Solutions; Particle Size; Permeability; Rabbits; Thiazoles | 2017 |
N-acetylcysteine-functionalized coating avoids bacterial adhesion and biofilm formation.
Topics: Acetylcysteine; Bacterial Adhesion; Biofilms; Chitosan; Coated Materials, Biocompatible; Materials Testing; Methicillin-Resistant Staphylococcus aureus; Surface Properties | 2017 |
Early results on the use of chitosan-N-acetylcysteine (Lacrimera
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Chitosan; Dry Eye Syndromes; Female; Follow-Up Studies; Humans; Keratitis; Lubricant Eye Drops; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Time Factors; Treatment Outcome | 2019 |
S-preactivated thiolated glycol chitosan useful to combine mucoadhesion and drug delivery.
Topics: Acetylcysteine; Adhesiveness; Caco-2 Cells; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Liberation; Excipients; Glutathione; Humans; Naproxen; Nicotinic Acids; Polymers; Sulfhydryl Compounds; Tablets | 2018 |
N-acetylcysteine reverses the decrease of DNA methylation status caused by engineered gold, silicon, and chitosan nanoparticles.
Topics: Acetylcysteine; Alu Elements; Apoptosis; Cell Cycle; Cell Line; Cell Survival; Chitosan; DNA Methylation; Epigenesis, Genetic; Gold; Humans; Keratinocytes; Long Interspersed Nucleotide Elements; Nanoparticles; Protein Corona; Reactive Oxygen Species; Silicon | 2019 |
Topics: Acetylcysteine; Caco-2 Cells; Chitosan; Curcumin; Cysteine; Drug Carriers; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Lactoglobulins; Molecular Docking Simulation; Nanoparticles; Particle Size; Peptides | 2019 |
Development of chitosan-coated liposome for pulmonary delivery of N-acetylcysteine.
Topics: Acetylcysteine; Chitosan; Cholesterol; Humans; Liposomes; Lung; Phosphatidylglycerols; Surface Properties | 2020 |
Management of moderate-to-severe dry eye disease using chitosan-N-acetylcysteine (Lacrimera®) eye drops: a retrospective case series.
Topics: Acetylcysteine; Adult; Aged; Chitosan; Dry Eye Syndromes; Female; Follow-Up Studies; Humans; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Tears; Treatment Outcome; Young Adult | 2020 |
Microstructured Lipid Carriers (MLC) Based on N-Acetylcysteine and Chitosan Preventing
Topics: Acetylcysteine; Anti-Infective Agents; Biofilms; Chitosan; Drug Delivery Systems; Drug Liberation; Lipids; Microbial Sensitivity Tests; Nanoparticles; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections | 2021 |
Mannose-anchored quaternized chitosan/thiolated carboxymethyl chitosan composite NPs as mucoadhesive carrier for drug delivery.
Topics: Acetylcysteine; Administration, Mucosal; Chemical Phenomena; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Liberation; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Macrophages; Mannose; Mucins; Nanoparticles; Particle Size | 2022 |
N-acetylcysteine functionalized chitosan oligosaccharide-palmitic acid conjugate enhances ophthalmic delivery of flurbiprofen and its mechanisms.
Topics: Acetylcysteine; Animals; Chickens; Chitosan; Cornea; Female; Flurbiprofen; Oligosaccharides; Palmitic Acid; Particle Size; Rabbits | 2022 |
Preparation, physicochemical, and retinal anti-angiogenic evaluation of poloxamer hydrogel containing dexamethasone/avastin-loaded chitosan-N-acetyl-L-cysteine nanoparticles.
Topics: Acetylcysteine; Bevacizumab; Chitosan; Dexamethasone; Hydrogels; Hypromellose Derivatives; Nanoparticles; Poloxamer | 2022 |
Preparation of inhalable N-acetylcysteine-loaded magnetite chitosan microparticles for nitrate adsorption in particulate matter.
Topics: Acetylcysteine; Adsorption; Air Pollutants; Chitosan; Ferrosoferric Oxide; Nitrates; Particulate Matter | 2023 |
Is nanoparaquat safer than bulk paraquat? An in vitro and in vivo evaluation.
Topics: Acetylcysteine; Antioxidants; Chitosan; HEK293 Cells; Herbicides; Humans; Hydroxyproline; Oxidative Stress; Paraquat | 2023 |
The protective effect of N-acetylcysteine against liposome and chitosan-induced cytotoxicity.
Topics: Acetylcysteine; Antioxidants; Chitosan; Drug Liberation; Liposomes; Nanoparticles; Particle Size | 2023 |
Long-circulating thiolated chitosan nanoparticles of nintedanib with N-acetyl cysteine for treating idiopathic pulmonary fibrosis: In vitro assessment of cytotoxicity, antioxidant, and antifibrotic potential.
Topics: Acetylcysteine; Antioxidants; Cell Line; Cell Survival; Chitosan; Humans; Idiopathic Pulmonary Fibrosis; Nanoparticles; Particle Size; Sulfhydryl Compounds | 2023 |
S-Protected Thiolated Chitosan versus Thiolated Chitosan as Cell Adhesive Biomaterials for Tissue Engineering.
Topics: Acetylcysteine; Biocompatible Materials; Carbodiimides; Chitosan; Cryogels; Tissue Engineering | 2023 |
Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis.
Topics: Acetylcysteine; Antimicrobial Peptides; Antitubercular Agents; Chitosan; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nanoparticles; Tuberculosis | 2024 |