Compounds > acetylcysteine

acetylcysteine and chenodeoxycholic acid

acetylcysteine has been researched along with chenodeoxycholic acid in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Way, LW1
Jun, EJ; Jung, SM; Kim, JK; Kim, KH; Kim, ND; Lee, S; Lim, YJ; Park, BS; Seo, SY; Suh, H; Yoo, YH1
Hainaut, P; Hautefeuille, A; Mion, F; Pétré, A; Roman, S; Scoazec, JY; Thépot, A1
Kang, DY; Kim, SH; Kim, TH; Park, KJ; Park, MK; Suh, H; Yoo, YH1

Reviews

1 review(s) available for acetylcysteine and chenodeoxycholic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for acetylcysteine and chenodeoxycholic acid

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vitro dissolution of cholesterol gallstones.
    Surgical forum, 1973, Volume: 24

    Topics: Acetylcysteine; Chenodeoxycholic Acid; Cholelithiasis; Cholic Acids; Deoxycholic Acid; Drug Combinations; Enzyme Therapy; Glycocholic Acid; Heparin; Humans; In Vitro Techniques; Pancreatin; Papain; Phosphatidylcholines; Taurocholic Acid; Trypsin

1973
Synthetic chenodeoxycholic acid derivative HS-1200-induced apoptosis of p815 mastocytoma cells is augmented by co-treatment with lactacystin.
    Anti-cancer drugs, 2003, Volume: 14, Issue:3

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Chenodeoxycholic Acid; Cysteine Endopeptidases; DNA Fragmentation; Drug Synergism; Mastocytoma; Membrane Potentials; Mice; Mitochondria; Multienzyme Complexes; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex

2003
Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:1

    Topics: Acetylcysteine; Apoptosis; Barrett Esophagus; Carcinoma, Squamous Cell; Cell Line, Tumor; Cells, Cultured; Chenodeoxycholic Acid; Cyclooxygenase 2; Deoxycholic Acid; DNA-Binding Proteins; Down-Regulation; Doxorubicin; Esophageal Neoplasms; Esophagus; Fluorescent Antibody Technique; Humans; Hydrogen-Ion Concentration; Leupeptins; Proteasome Inhibitors; Taurochenodeoxycholic Acid; Trans-Activators; Transcription Factors; Tumor Suppressor Proteins

2007
Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin.
    International journal of oncology, 2009, Volume: 34, Issue:5

    Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma; Cell Survival; Chenodeoxycholic Acid; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Mitochondria; Thyroid Neoplasms; Treatment Outcome; Tumor Cells, Cultured; Valproic Acid

2009