acetylcysteine and carboplatin

acetylcysteine has been researched along with carboplatin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's4 (40.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Benbow, U; Brinckerhoff, CE; Hamilton, JW; Maitra, R1
Bennett, LC; Hale, C; Muldoon, LL; Neuwelt, EA; Purcell, SE; Walker-Rosenfeld, SL1
Beijnen, JH; Huitema, AD; Rodenhuis, S; van Maanen, MJ1
Kilic, MA; Kilinc, M; Okur, E; Tolun, FI; Yildirim, I1
Chang, CC; Chen, CC; Cheng, CF; Chou, Y; Juan, SH; Li, HF; Lin, H; Sue, YM1
Bhat, MK; Chaube, B; Pandey, V1
Cao, L; Cheng, WH; Fu, Y; Tzeng, TJ; Zeng, H1
Butini, S; Campiani, G; Lennon, JC; O'Meara, A; Williams, DC; Zisterer, DM1
Cao, S; Han, B; Ling, X; Wang, H; Xu, J; Zhang, B; Zhang, X; Zhong, H; Zhong, R1
Bartos, P; Bartunkova, J; Chovanec, J; Cibula, D; Fucikova, J; Hraska, M; Hrnciarova, T; Kieszko, D; Klat, J; Knapp, P; Korolkiewicz, RP; Mallmann, P; Melichar, B; Minar, L; Novotny, Z; Pluta, M; Rob, L; Spacek, J; Spisek, R; Valha, P1

Trials

2 trial(s) available for acetylcysteine and carboplatin

ArticleYear
Safety and efficacy of dendritic cell-based immunotherapy (DCVAC/LuCa) combined with carboplatin/pemetrexed for patients with advanced non-squamous non-small-cell lung cancer without oncogenic drivers.
    ESMO open, 2022, Volume: 7, Issue:1

    Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Dendritic Cells; Humans; Immunotherapy; Lung Neoplasms; Pemetrexed; Prospective Studies

2022
Safety and efficacy of dendritic cell-based immunotherapy DCVAC/OvCa added to first-line chemotherapy (carboplatin plus paclitaxel) for epithelial ovarian cancer: a phase 2, open-label, multicenter, randomized trial.
    Journal for immunotherapy of cancer, 2022, Volume: 10, Issue:1

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Ovarian Epithelial; Dendritic Cells; Female; Humans; Immunotherapy; Mice; Middle Aged; Paclitaxel; Young Adult

2022

Other Studies

8 other study(ies) available for acetylcysteine and carboplatin

ArticleYear
Selective inhibition of collagenase-1, gelatinase A, and gelatinase B by chemotherapeutic agents.
    Annals of the New York Academy of Sciences, 1999, Jun-30, Volume: 878

    Topics: Acetylcysteine; Antineoplastic Agents; Carboplatin; Cisplatin; Doxorubicin; Gelatinases; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Melanoma; Metalloendopeptidases; Mitomycin; Neoplasm Invasiveness; Protease Inhibitors; Tumor Cells, Cultured

1999
Rescue from enhanced alkylator-induced cell death with low molecular weight sulfur-containing chemoprotectants.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: Acetylcysteine; Alkylating Agents; Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Carboplatin; Cell Survival; Cytoprotection; Drug Interactions; Humans; Molecular Weight; Protective Agents; Thiosulfates; Time Factors; Tumor Cells, Cultured

2001
Urinary excretion of thioTEPA and its metabolites in patients treated with high-dose cyclophosphamide, thioTEPA and carboplatin.
    Anti-cancer drugs, 2001, Volume: 12, Issue:6

    Topics: Acetylcysteine; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Breast Neoplasms; Carboplatin; Creatinine; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Models, Chemical; Neoplasms, Germ Cell and Embryonal; Thiotepa; Time Factors; Triethylenephosphoramide

2001
Effect of N-acetylcysteine on carboplatin-induced ototoxicity and nitric oxide levels in a rat model.
    The Laryngoscope, 2007, Volume: 117, Issue:12

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Biomarkers; Carboplatin; Cochlea; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Follow-Up Studies; Free Radical Scavengers; Glutathione Peroxidase; Hearing Loss, Sensorineural; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spectrophotometry; Treatment Outcome

2007
Activation of a nuclear factor of activated T-lymphocyte-3 (NFAT3) by oxidative stress in carboplatin-mediated renal apoptosis.
    British journal of pharmacology, 2010, Volume: 161, Issue:7

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Carboplatin; Caspase 3; Cell Nucleus; Epithelial Cells; Kidney Tubules; Luciferases; Mice; Mice, Transgenic; NADPH Oxidases; NFATC Transcription Factors; Oxidative Stress; Protein Carbonylation; Reactive Oxygen Species; Transfection

2010
Hyperglycemia regulates MDR-1, drug accumulation and ROS levels causing increased toxicity of carboplatin and 5-fluorouracil in MCF-7 cells.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:10

    Topics: Acetylcysteine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carboplatin; Cell Line, Tumor; Female; Fluorouracil; Glucose; Humans; Hyperglycemia; Inhibitory Concentration 50; NF-kappa B; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Verapamil

2011
Methylseleninic acid sensitizes Notch3-activated OVCA429 ovarian cancer cells to carboplatin.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Acetylcysteine; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Carboplatin; Cell Cycle; Cell Line, Tumor; Chromones; DNA-Binding Proteins; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Morpholines; Organoselenium Compounds; Ovarian Neoplasms; Phosphorylation; Receptor, Notch3; Receptors, Notch; RNA, Messenger; Thioxanthenes

2014
Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine-induced apoptosis in neuroblastoma cells.
    Investigational new drugs, 2016, Volume: 34, Issue:5

    Topics: Acetyl-CoA Carboxylase; Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Carboplatin; Cell Line, Tumor; Female; Humans; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Neuroblastoma; Oxazepines; Phosphorylation; Pyrroles; Reactive Oxygen Species; Tubulin Modulators; Tumor Burden

2016