acetylcysteine and carbon tetrachloride

acetylcysteine has been researched along with carbon tetrachloride in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's4 (15.38)18.2507
2000's5 (19.23)29.6817
2010's14 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Katz, J; Michael, S; Oberstein, E; Popescu, A; Simko, V1
Flanagan, RJ; Mant, TG; Ruprah, M1
Alp, MH; Hickman, R1
MacSweeney, JE; Mathieson, PW; Williams, G1
Castro, JA; de Castro, CR; Valles, EG1
De Bleser, PJ; Geerts, A; Rogiers, V; Rombouts, K; Xu, G1
Buck, M; Chojkier, M; Hunter, T; Poli, V1
Bozek, P; Greksák, M; Gvozdjáková, A; Kucharská, J; Nakano, M; Sumbalová, Z; Ulicná, O; Vancová, O1
Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J1
Kuiper, HC; Miranda, CL; Sowell, JD; Stevens, JF1
Galicia-Moreno, M; Moreno, MG; Muriel, P; Reyes-Gordillo, K; Rodríguez-Rivera, A; Segovia, J; Shibayama, M; Tsutsumi, V; Vergara, P1
Hirst, SM; Karakoti, A; Reilly, CM; Seal, S; Self, W; Singh, S; Tyler, R1
Bala, A; Haldar, PK; Kar, B; Mazumder, UK; Naskar, S1
Abdalla, AM; Abdelwahab, SA; Mahmoud, AM; Mahmoud, ME; Morsy, MA1
Jiang, R; Lu, H; Peng, X; Wan, J; Xie, J; Zhang, L1
Alatas, O; Sahin, S1
Adil, HS; Afnan, Q; Bhushan, S; Farrukh, MR; Kaiser, PJ; Nissar, AU; Rafiq, RA; Subhash, BC; Tasduq, SA1
Atli, Y; Bulbuloglu, E; Cetinkaya, A; Ciralik, H; Kantarceken, B; Kurutas, EB1
Aksit, H; Bildik, A1
Cai, Z; Fang, H; Ju, L; Li, E; Lou, Q; Sun, J; Wang, F; Xi, J1
Guo, M; Shao, J; Zhang, Z; Zhao, S; Zheng, S1
Janega, P; Luha, J; Muchová, J; Otrubová, O; Turecký, L; Uličná, O1
Chen, A; Guo, Q; Jia, Y; Jiang, S; Jin, H; Li, M; Shao, J; Tan, S; Wang, F; Wang, L; Zhang, F; Zhang, Z; Zheng, S1

Reviews

1 review(s) available for acetylcysteine and carbon tetrachloride

ArticleYear
Therapeutic effects of N-acetyl-L-cysteine on liver damage induced by long-term CCl4 administration.
    General physiology and biophysics, 2018, Volume: 37, Issue:1

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Liver; Male; Rats; Rats, Wistar; Treatment Outcome

2018

Other Studies

25 other study(ies) available for acetylcysteine and carbon tetrachloride

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Carbon tetrachloride toxicity. Agency for Toxic Substances and Disease Registry.
    American family physician, 1992, Volume: 46, Issue:4

    Topics: Acetylcysteine; Adult; Aftercare; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Female; Free Radical Scavengers; Humans; Kidney Function Tests; Liver Function Tests; Male; Medical History Taking; Occupational Diseases; Physical Examination; Pregnancy; Prognosis; Risk Factors

1992
Protective effect of oral acetylcysteine against the hepatorenal toxicity of carbon tetrachloride potentiated by ethyl alcohol.
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:4

    Topics: Acetylcysteine; Alcoholism; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Creatinine; Ethanol; Glutathione; Kidney; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Male; Rats; Rats, Inbred Strains

1992
Acute carbon tetrachloride poisoning in 19 patients: implications for diagnosis and treatment.
    Lancet (London, England), 1985, May-04, Volume: 1, Issue:8436

    Topics: Acetaminophen; Acetylcysteine; Acute Disease; Adolescent; Adult; Aged; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Child; Child, Preschool; Chromatography, Gas; Female; Humans; Male; Middle Aged

1985
The effect of prostaglandins, branched-chain amino acids and other drugs on the outcome of experimental acute porcine hepatic failure.
    Journal of hepatology, 1987, Volume: 4, Issue:1

    Topics: Acetylcysteine; Amino Acids, Branched-Chain; Amino Acids, Essential; Animals; Carbon Tetrachloride; Cholestyramine Resin; Disease Models, Animal; Hepatic Encephalopathy; Phosphatidylcholines; Prostaglandins; Silymarin; Swine

1987
Survival after massive ingestion of carbon tetrachloride treated by intravenous infusion of acetylcysteine.
    Human toxicology, 1985, Volume: 4, Issue:6

    Topics: Acetylcysteine; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Humans; Infusions, Parenteral; Male; Middle Aged; Osteitis Deformans; Prothrombin; Psychotic Disorders; Radiography; Suicide, Attempted

1985
N-acetyl cysteine is an early but also a late preventive agent against carbon tetrachloride-induced liver necrosis.
    Toxicology letters, 1994, Volume: 71, Issue:1

    Topics: Acetylcysteine; Animals; Carbon Tetrachloride; Lipid Peroxidation; Liver; Male; Microsomes, Liver; Necrosis; Rats; Rats, Sprague-Dawley

1994
Glutathione levels discriminate between oxidative stress and transforming growth factor-beta signaling in activated rat hepatic stellate cells.
    The Journal of biological chemistry, 1999, Nov-26, Volume: 274, Issue:48

    Topics: Acetylcysteine; Animals; Blotting, Northern; Carbon Tetrachloride; Catalase; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Superoxide Dismutase; Transforming Growth Factor beta; Vitamin K

1999
C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival.
    Molecular cell, 2001, Volume: 8, Issue:4

    Topics: Acetylcysteine; Amino Acid Motifs; Animals; Apoptosis; Carbon Tetrachloride; Caspase Inhibitors; Caspases; CCAAT-Enhancer-Binding Protein-beta; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Enzyme Activation; Enzyme Precursors; Hepatocytes; Humans; Liver Cirrhosis, Experimental; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Phosphorylation; Rats; Recombinant Proteins; Ribosomal Protein S6 Kinases

2001
Regeneration of coenzyme Q9 redox state and inhibition of oxidative stress by Rooibos tea (Aspalathus linearis) administration in carbon tetrachloride liver damage.
    Physiological research, 2004, Volume: 53, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Aspalathus; Beverages; Carbon Tetrachloride; Liver Failure, Acute; Liver Regeneration; Male; Oxidation-Reduction; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Treatment Outcome; Ubiquinone

2004
Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats.
    Critical care medicine, 2004, Volume: 32, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Deferoxamine; Hydrocarbons; Inflammation; Liver; Liver Failure, Acute; Male; Models, Animal; Necrosis; Oxidative Stress; Rats; Rats, Wistar

2004
Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress.
    The Journal of biological chemistry, 2008, Jun-20, Volume: 283, Issue:25

    Topics: Acetylcysteine; Aldehydes; Animals; Biomarkers; Carbon Tetrachloride; Chromatography, Liquid; Lactones; Linoleic Acid; Lipid Peroxidation; Mass Spectrometry; Models, Chemical; Oxidative Stress; Rats; Rats, Inbred F344

2008
N-acetylcysteine prevents carbon tetrachloride-induced liver cirrhosis: role of liver transforming growth factor-beta and oxidative stress.
    European journal of gastroenterology & hepatology, 2009, Volume: 21, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Liver Cirrhosis, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Transforming Growth Factor beta

2009
Bio-distribution and in vivo antioxidant effects of cerium oxide nanoparticles in mice.
    Environmental toxicology, 2013, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Cell Line; Cerium; Female; Free Radical Scavengers; Kidney; Liver; Lung; Mice; Nanoparticles; Oxidative Stress; Reactive Oxygen Species; Spleen

2013
Carbon tetrachloride: a hepatotoxin causes oxidative stress in murine peritoneal macrophage and peripheral blood lymphocyte cells.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:1

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Free Radical Scavengers; Lipid Peroxidation; Lymphocytes; Macrophages, Peritoneal; Mice; Oxidative Stress; Superoxides

2012
Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats.
    Journal of physiology and biochemistry, 2012, Volume: 68, Issue:1

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Curcumin; gamma-Glutamyltransferase; Glutathione; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinase 13; Rats; Rats, Wistar; Thioctic Acid; Transforming Growth Factor alpha

2012
Sodium butyrate potentiates carbon tetrachloride-induced acute liver injury in mice.
    Toxicology mechanisms and methods, 2012, Volume: 22, Issue:8

    Topics: Acetylcysteine; Animals; Butyrates; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Liver; Male; Mice; Oxidative Stress; Thioctic Acid

2012
The protective effects of n-acetylcysteine against acute hepatotoxicity.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2013, Volume: 32, Issue:5

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Malondialdehyde; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley

2013
Effect of N-acetyl cysteine (NAC), an organosulfur compound from Allium plants, on experimentally induced hepatic prefibrogenic events in Wistar rat.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Jul-15, Volume: 20, Issue:10

    Topics: Acetylcysteine; Allium; Animals; Carbon Tetrachloride; Disease Models, Animal; Liver Cirrhosis; Male; Oxidative Stress; Phytotherapy; Rats; Rats, Wistar; Sulfur; Thioacetamide

2013
The effects of L-carnitine and N-acetylcysteine on carbontetrachloride induced acute liver damage in rats.
    Bratislavske lekarske listy, 2013, Volume: 114, Issue:12

    Topics: Acetylcysteine; Animals; Carbon Tetrachloride; Carnitine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Free Radical Scavengers; Liver; Oxidative Stress; Rats; Rats, Wistar; Vitamin B Complex

2013
Determination of DNA damage in experimental liver intoxication and role of N-acetyl cysteine.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:2

    Topics: Acetylation; Acetylcysteine; Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA Damage; Histone Acetyltransferases; Histone Deacetylases; Histones; Liver; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley

2014
N-acetylcysteine protects against liver injure induced by carbon tetrachloride via activation of the Nrf2/HO-1 pathway.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:7

    Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Heme Oxygenase (Decyclizing); Liver; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Up-Regulation

2015
ROS-JNK1/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: Acetylcysteine; Animals; Anthracenes; Anti-Inflammatory Agents; Antioxidants; Artemisinins; Autophagy; Carbon Tetrachloride; Gene Expression Regulation; Glutathione; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering

2016
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
    Redox biology, 2018, Volume: 19

    Topics: Acetylcysteine; Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Hepatic Stellate Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Necrosis; Phosphorylation; Random Allocation; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Sesquiterpenes

2018