acetylcysteine and camptothecin

acetylcysteine has been researched along with camptothecin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Kline, I1
Doneanu, CE; Niture, SK; Pattabiraman, N; Srivenugopal, KS; Velu, CS1
Hergenrother, PJ; Hoyt, MT; Palchaudhuri, R1
Gleyzer, N; Scarpulla, RC1
Ito, K; Izumi, H; Kohno, K; Li, Z; Liu, YP; Nakayama, Y; Uramoto, H; Wang, KY; Wu, Y1
Chang, WT; Chen, JY; Chiu, CC; Chou, HL; Fong, Y; Huang, HW; Tsai, EM; Wei, CK; Wu, CY1
Gong, X; Li, C; Li, Q; Zhang, H; Zhao, X1

Other Studies

9 other study(ies) available for acetylcysteine and camptothecin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Potentially useful combinations of chemotherapy detected in mouse tumor systems.
    Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes

1974
Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.
    Biochemistry, 2007, Jul-03, Volume: 46, Issue:26

    Topics: Acetylcysteine; Amino Acid Sequence; Binding Sites; Buthionine Sulfoximine; Camptothecin; Cell Line, Tumor; Cross-Linking Reagents; Cysteine; Diamide; DNA Damage; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutaral; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Models, Molecular; Oxidative Stress; Phosphorylation; Recombinant Proteins; Tandem Mass Spectrometry; tert-Butylhydroperoxide; Tumor Suppressor Protein p53

2007
Cribrostatin 6 induces death in cancer cells through a reactive oxygen species (ROS)-mediated mechanism.
    Investigational new drugs, 2011, Volume: 29, Issue:4

    Topics: 3T3 Cells; Acetylcysteine; Animals; Camptothecin; Cell Cycle; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cytoprotection; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Down-Regulation; Drug Screening Assays, Antitumor; Ethidium; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Humans; Isoquinolines; Mice; Reactive Oxygen Species; RNA, Messenger; Up-Regulation

2011
Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence.
    The Journal of biological chemistry, 2013, Mar-22, Volume: 288, Issue:12

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Camptothecin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Tumor; Cell Survival; Cellular Senescence; Cornified Envelope Proline-Rich Proteins; Gene Expression; Gene Knockdown Techniques; Histamine H1 Antagonists; Humans; Inflammation; Irinotecan; Kinetics; Meclizine; Oxidants; Oxidative Stress; Proto-Oncogene Proteins c-myc; Proton Ionophores; RNA, Small Interfering; Topoisomerase I Inhibitors; Transcription Factors; Transcriptional Activation; Vitamin K 3

2013
Y-box binding protein 1 enhances DNA topoisomerase 1 activity and sensitivity to camptothecin via direct interaction.
    Journal of experimental & clinical cancer research : CR, 2014, Dec-24, Volume: 33

    Topics: Acetylcysteine; Antioxidants; Binding Sites; Camptothecin; Catalysis; Cell Line, Tumor; DNA Topoisomerases, Type I; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Nucleic Acid Conformation; Oxidative Stress; Protein Binding; Protein Interaction Domains and Motifs; RNA Interference; Topoisomerase I Inhibitors; Transfection; Y-Box-Binding Protein 1

2014
A Quinone-Containing Compound Enhances Camptothecin-Induced Apoptosis of Lung Cancer Through Modulating Endogenous ROS and ERK Signaling.
    Archivum immunologiae et therapiae experimentalis, 2017, Volume: 65, Issue:3

    Topics: A549 Cells; Acetylcysteine; Antineoplastic Agents; Apoptosis; Benzoquinones; Camptothecin; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mitochondria; Putrescine; Reactive Oxygen Species

2017
Synthesis, characterization, and cytotoxicity assessment of N-acetyl-l-cysteine capped ZnO nanoparticles as camptothecin delivery system.
    Colloids and surfaces. B, Biointerfaces, 2019, Feb-01, Volume: 174

    Topics: A549 Cells; Acetylcysteine; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Drug Delivery Systems; Hemolysis; Humans; Metal Nanoparticles; Zinc Oxide

2019