acetylcysteine and calpain

acetylcysteine has been researched along with calpain in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	16 (37.21)	18.2507
2000's	17 (39.53)	29.6817
2010's	9 (20.93)	24.3611
2020's	1 (2.33)	2.80

Authors

Authors	Studies
Bush, KT; Goldberg, AL; Nigam, SK	1
Bartunik, HD; Bochtler, M; Ditzel, L; Groll, M; Huber, R; Löwe, J; Stock, D	1
Haass, C; Ihara, Y; Omura, S; Saido, TC; Yamazaki, T	1
Mellgren, RL	2
Choi, YH; Henkart, PA; Jang, JS; Lee, J; Lee, SJ; Maki, M; Nguyen, P; Takano, E; Trepel, JB; Wu, ML	1
Ozols, J	1
Bonvini, P; Neckers, LM; Nguyen, P; Trepel, J	1
Elce, J; Forsberg, NE; Huang, J; Ichihara, A; Ou, BR; Tanaka, K; Ueda, Y; Wang, MC	1
Di Sano, F; Oliverio, S; Piacentini, M; Spinedi, A	1
Andersson, M; Karlsson, JO; Kling-Petersen, A; Sjöstrand, J	1
Orrenius, S; Pörn-Ares, MI; Samali, A	1
Choi, YH; Henkart, PA; Hwang, SG; Jang, JS; Lee, J; Lee, SJ; Maki, M; Nguyen, PM; Takano, E; Trepel, JB; Wu, ML	1
Gnegy, ME; McGinnis, KM; Mukerjee, N; Park, YH; Wang, KK	1
Asakura, T; Hashizume, Y; Ohkawa, K; Okawa, Y; Sawai, T; Takada, K; Yanaihara, N	1
Choi, YH; Jang, JS	1
Karlsson, JO; Lundquist, J; Nilsson, M; Skoglund, I	1
An, WG; Blagosklonny, MV; Hwang, SG; Trepel, JB	1
Masaki, R; Ohtani-Kaneko, R; Saito, T; Yamada, K	1
Eissa, NT; Musial, A	1
Mezey, E; Potter, JJ; Rennie-Tankersley, L	1
Morley, SJ; Pain, VM	1
Botion, LM; Brasier, AR; Green, A; Tian, B; Udupi, V	1
Burton, GR; Lyle, RE; May, JS; McGehee, RE; Prince, AM	1
Engström, A; Larsson, M; Rask, L; Sakwe, AM	1
Almazan, G; Giasson, BI; Liu, HN; Mushynski, WE	1
Kerokoski, P; Pirttilä, T; Salminen, A; Soininen, H; Suuronen, T	1
Imai, K; Kunimatsu, M; Liu, ZQ; Manabe, T; Okamoto, T; Sasaki, M; Takeyama, H; Teranishi, F	1
Ahn, MT; Kalbe, L; Kruhoffer, M; Leunda, A; Meulemans, C; Nerup, J; Orntoft, T; Remacle, C; Reusens, B; Sparre, T	1
Dnyanmote, AV; Latendresse, JR; Lock, EA; Mehendale, HM; Sawant, SP; Warbritton, AA	1
Inomata, M; Nakamura, M; Ohno, H; Shintani-Ishida, K; Uemura, K; Yoshida, K	1
Cheung, NS; Halliwell, B; Koh, CH; Li, QT; Manikandan, J; Melendez, AJ; Peng, ZF; Tang, SY	1
Balakrishnan, K; Gandhi, V; Keating, MJ; Wierda, WG	1
Agten, A; Decramer, M; Gayan-Ramirez, G; Maes, K; Powers, SK; Smuder, A	1
Jantas, D; Kubera, M; Lason, W; Lorenc-Koci, E	1
Benbow, JH; DeGray, B; Ehrlich, BE	1
Chen, SH; Gean, PW; Hsiao, YH; Kuo, JR	1
Breysse, PN; Garcia, JG; Geyh, AS; Lang, GD; Mathew, B; Moreno-Vinasco, L; Natarajan, V; Samet, JM; Siegler, JH; Usatyuk, PV; Wang, L; Wang, T	1
Dalbo, VJ; Kerksick, CM; Kreider, RB; Roberts, MD; Willoughby, DS	1
Dai, J; Dai, K; Du, J; Liu, G; Wang, X; Yan, R; Zhang, F; Zhang, P; Zhang, Y; Zhao, L	1
Alkanat, M; Mungan, S; Orem, A; Ozkan, G; Ulusoy, S; Yucesan, FB; Yulug, E	1
Leng, B; Nie, Q; Wang, H; Zhang, L; Zhu, L	1
Bando, K; Kaji, T; Kuroishi, T; Sugawara, S; Takahashi, M	1

Other Studies

43 other study(ies) available for acetylcysteine and calpain

Article	Year
Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance. The Journal of biological chemistry, 1997, Apr-04, Volume: 272, Issue:14 Topics: Acetylcysteine; Animals; Calpain; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dogs; Endoplasmic Reticulum; Fungal Proteins; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Leupeptins; Membrane Glycoproteins; Membrane Proteins; Molecular Chaperones; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Conformation; RNA, Messenger	1997
Structure of 20S proteasome from yeast at 2.4 A resolution. Nature, 1997, Apr-03, Volume: 386, Issue:6624 Topics: Acetylcysteine; Calpain; Crystallography, X-Ray; Cysteine Endopeptidases; Endopeptidases; Enzyme Inhibitors; Enzyme Precursors; Glycoproteins; Histocompatibility Antigens Class I; Models, Molecular; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Conformation; Saccharomyces cerevisiae; Thermoplasma; Threonine	1997
Specific increase in amyloid beta-protein 42 secretion ratio by calpain inhibition. Biochemistry, 1997, Jul-08, Volume: 36, Issue:27 Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Calcimycin; Calcium-Binding Proteins; Calpain; Cell Line; Cysteine Proteinase Inhibitors; Dipeptides; Embryo, Mammalian; Humans; Kidney; Peptide Fragments; Transfection	1997
Evidence for participation of a calpain-like cysteine protease in cell cycle progression through late G1 phase. Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3 Topics: Acetylcysteine; Calpain; Cell Cycle; Cell Line; Cysteine Proteinase Inhibitors; Diazomethane; Fibroblasts; G1 Phase; Humans; Leupeptins; Oligopeptides; S Phase	1997
Regulation of cyclin D1 by calpain protease. The Journal of biological chemistry, 1997, Nov-07, Volume: 272, Issue:45 Topics: 3T3 Cells; Acetylcysteine; Animals; Calpain; Cyclin B; Cyclin B1; Cyclin D1; Cysteine Proteinase Inhibitors; Dactinomycin; Half-Life; Humans; Male; Mice; Prostatic Neoplasms; Protein Synthesis Inhibitors; Tumor Cells, Cultured	1997
Degradation of hepatic stearyl CoA delta 9-desaturase. Molecular biology of the cell, 1997, Volume: 8, Issue:11 Topics: Acetylcysteine; Animals; Calpain; Cell Fractionation; Cysteine Proteinase Inhibitors; Hydrogen-Ion Concentration; Liver; Lysosomes; Male; Microsomes; Molecular Weight; Rats; Rats, Sprague-Dawley; Sequence Analysis; Serine Proteinase Inhibitors; Stearoyl-CoA Desaturase; Temperature	1997
Specificities of cell permeant peptidyl inhibitors for the proteinase activities of mu-calpain and the 20 S proteasome. The Journal of biological chemistry, 1997, Nov-21, Volume: 272, Issue:47 Topics: Acetylcysteine; Calcium-Binding Proteins; Calpain; Catalysis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diazomethane; Enzyme Precursors; Humans; Kinetics; Leupeptins; Multienzyme Complexes; Muramidase; Oligopeptides; Plant Proteins; Protease Inhibitors; Proteasome Endopeptidase Complex; Saccharomyces cerevisiae; Serine Proteinase Inhibitors; Ubiquitins	1997
In vivo degradation of N-myc in neuroblastoma cells is mediated by the 26S proteasome. Oncogene, 1998, Mar-05, Volume: 16, Issue:9 Topics: Acetylcysteine; Calpain; Cysteine Proteinase Inhibitors; Humans; Lysosomes; Neuroblastoma; Peptide Hydrolases; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-myc; Substrate Specificity; Tumor Cells, Cultured; Ubiquitins	1998
Evidence for the participation of the proteasome and calpain in early phases of muscle cell differentiation. The international journal of biochemistry & cell biology, 1998, Volume: 30, Issue:6 Topics: Acetylcysteine; Adenosine Triphosphatases; Animals; Calpain; Carrier Proteins; Cell Differentiation; Cell Line; Creatine Kinase; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Iron-Binding Proteins; Multienzyme Complexes; Muscles; Myogenin; Oligopeptides; Proteasome Endopeptidase Complex; Rats; Transferrin-Binding Proteins	1998
Calpain involvement in calphostin C-induced apoptosis. Biochemical pharmacology, 1998, Dec-01, Volume: 56, Issue:11 Topics: Acetylcysteine; Antibiotics, Antineoplastic; Apoptosis; Calpain; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Multienzyme Complexes; Naphthalenes; Neoplasm Proteins; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; U937 Cells; Ubiquitins	1998
Proteolysis in human lens epithelium determined by a cell-permeable substrate. Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:1 Topics: Acetylcysteine; Calcium; Calpain; Cell Membrane Permeability; Cell Survival; Coumarins; Cysteine Endopeptidases; Enzyme Inhibitors; Epithelium; Humans; Ionomycin; L-Lactate Dehydrogenase; Lens, Crystalline; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Substrate Specificity; Thapsigargin	1999
Cleavage of the calpain inhibitor, calpastatin, during apoptosis. Cell death and differentiation, 1998, Volume: 5, Issue:12 Topics: Acetylcysteine; Apoptosis; Calcium-Binding Proteins; Calpain; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; fas Receptor; Flow Cytometry; Humans; Jurkat Cells; Pepstatins; Protease Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha; U937 Cells	1998
Posttranslational regulation of the retinoblastoma gene family member p107 by calpain protease. Oncogene, 1999, Mar-11, Volume: 18, Issue:10 Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Bucladesine; Calpain; Cyclin B; Cyclin B1; Cysteine Proteinase Inhibitors; Dipeptides; Fluorouracil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ketones; Leupeptins; Lovastatin; Nuclear Proteins; Protein Processing, Post-Translational; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Tumor Cells, Cultured	1999
Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates. Biochemical and biophysical research communications, 1999, Sep-16, Volume: 263, Issue:1 Topics: Acetylcysteine; Aspartic Acid; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Precursors; Humans; Marine Toxins; Oxocins; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Staurosporine; Substrate Specificity	1999
Calpain inhibitor causes accumulation of ubiquitinated P-glycoprotein at the cell surface: possible role of calpain in P-glycoprotein turnover. International journal of oncology, 1999, Volume: 15, Issue:4 Topics: Acetylcysteine; Ammonium Chloride; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Brefeldin A; Calpain; Cell Membrane; Cysteine Proteinase Inhibitors; Dipeptides; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; K562 Cells; Leucine; Leupeptins; Membrane Proteins; Protein Synthesis Inhibitors; Time Factors; Ubiquitins	1999
Proteolytic degradation of the retinoblastoma family protein p107: A putative cooperative role of calpain and proteasome. International journal of molecular medicine, 1999, Volume: 4, Issue:5 Topics: Acetylcysteine; Antineoplastic Agents; Blotting, Western; Calcium-Binding Proteins; Calpain; CDC2-CDC28 Kinases; Cell Cycle; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Humans; Lovastatin; Male; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Sarcoma, Ewing; Transfection; Tumor Cells, Cultured; Ubiquitins	1999
Proteolytic activity in intact sheets of polarized epithelial cells as determined by a cell-permeable fluorogenic substrate. Cell biology international, 2000, Volume: 24, Issue:4 Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Calcium; Calpain; Cell Polarity; Cells, Cultured; Colforsin; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Epithelial Cells; Fluorescence; L-Lactate Dehydrogenase; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Swine; Thyroid Gland	2000
Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. Leukemia, 2000, Volume: 14, Issue:7 Topics: Acetylcysteine; Acrylates; Amino Acid Chloromethyl Ketones; Apoptosis; Boronic Acids; Bortezomib; Calpain; Cathepsins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Drug Synergism; Genes, p53; Humans; Jurkat Cells; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; U937 Cells	2000
Accumulation of phosphorylated neurofilaments and increase in apoptosis-specific protein and phosphorylated c-Jun induced by proteasome inhibitors. Journal of neuroscience research, 2000, Oct-01, Volume: 62, Issue:1 Topics: Acetylcysteine; Alkaline Phosphatase; Animals; Calpain; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Leupeptins; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neurites; Neurofilament Proteins; PC12 Cells; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-jun; Rats; Ubiquitins	2000
Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway. The Journal of biological chemistry, 2001, Jun-29, Volume: 276, Issue:26 Topics: Acetylcysteine; Alternative Splicing; Animals; Calpain; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytokines; Dimerization; Enzyme Inhibitors; Enzyme Stability; Humans; Lysosomes; Mice; Multienzyme Complexes; Mutation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Serine Proteinase Inhibitors; Transcription, Genetic	2001
Liver alcohol dehydrogenase is degraded by the ubiquitin-proteasome pathway. Biochemical and biophysical research communications, 2001, Jul-20, Volume: 285, Issue:3 Topics: Acetylcysteine; Adenine; Alcohol Dehydrogenase; Animals; Calpain; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dihydrotestosterone; Electrophoresis, Polyacrylamide Gel; Hepatocytes; Leupeptins; Liver; Lysosomes; Male; Multienzyme Complexes; Precipitin Tests; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Ubiquitins	2001
Proteasome inhibitors and immunosuppressive drugs promote the cleavage of eIF4GI and eIF4GII by caspase-8-independent mechanisms in Jurkat T cell lines. FEBS letters, 2001, Aug-17, Volume: 503, Issue:2-3 Topics: Acetylcysteine; Apoptosis; Calpain; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Eukaryotic Initiation Factor-4G; fas Receptor; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Jurkat Cells; Leupeptins; Multienzyme Complexes; Peptide Fragments; Peptide Initiation Factors; Propylene Glycols; Proteasome Endopeptidase Complex; Sphingosine; T-Lymphocytes	2001
Inhibition of proteasome activity blocks the ability of TNF alpha to down-regulate G(i) proteins and stimulate lipolysis. Endocrinology, 2001, Volume: 142, Issue:12 Topics: Acetylcysteine; Adipocytes; Animals; Calpain; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Down-Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Lipolysis; Male; Multienzyme Complexes; Phenylisopropyladenosine; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	2001
Proteasomal degradation of retinoblastoma-related p130 during adipocyte differentiation. Biochemical and biophysical research communications, 2002, Jan-25, Volume: 290, Issue:3 Topics: Acetylcysteine; Adipocytes; Animals; Calpain; Cell Differentiation; Cell Line; Cysteine Proteinase Inhibitors; Kinetics; Leupeptins; Nuclear Proteins; Peptide Hydrolases; Phosphoproteins; Proteasome Endopeptidase Complex; Proteins; Retinoblastoma-Like Protein p130	2002
Biosynthesis and secretion of parathyroid hormone are sensitive to proteasome inhibitors in dispersed bovine parathyroid cells. The Journal of biological chemistry, 2002, May-17, Volume: 277, Issue:20 Topics: Acetylcysteine; Animals; Brefeldin A; Calpain; Cattle; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; HSP70 Heat-Shock Proteins; Multienzyme Complexes; Parathyroid Glands; Parathyroid Hormone; Proteasome Endopeptidase Complex; Protein Precursors	2002
AMPA receptor-mediated toxicity in oligodendrocyte progenitors involves free radical generation and activation of JNK, calpain and caspase 3. Journal of neurochemistry, 2002, Volume: 82, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Calcium; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cytoprotection; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Free Radicals; Glutathione; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Neurotoxins; Oligodendroglia; Rats; Receptors, AMPA; Signal Transduction; Spectrin; Stem Cells	2002
Influence of phosphorylation of p35, an activator of cyclin-dependent kinase 5 (cdk5), on the proteolysis of p35. Brain research. Molecular brain research, 2002, Oct-15, Volume: 106, Issue:1-2 Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Animals, Newborn; Brain Chemistry; Calpain; Cells, Cultured; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Embryo, Mammalian; Enzyme Inhibitors; Hippocampus; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Okadaic Acid; Phosphorylation; Proteasome Endopeptidase Complex; Purines; Rats; Rats, Wistar; Roscovitine	2002
Calpain is involved in the HIV replication from the latently infected OM10.1 cells. Biochemical and biophysical research communications, 2003, Apr-11, Volume: 303, Issue:3 Topics: Acetylcysteine; Binding Sites; Calcimycin; Calcium Signaling; Calcium-Binding Proteins; Calpain; Cell Line; Glycoproteins; HIV-1; Humans; I-kappa B Proteins; In Vitro Techniques; Ionophores; Leucine; NF-kappa B; NF-KappaB Inhibitor alpha; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Virus Replication	2003
Nutritional regulation of proteases involved in fetal rat insulin secretion and islet cell proliferation. The British journal of nutrition, 2005, Volume: 93, Issue:3 Topics: Acetylcysteine; Animals; Calcium-Binding Proteins; Calpain; Cell Proliferation; Cells, Cultured; Diet, Protein-Restricted; Disease Models, Animal; Female; Fetal Nutrition Disorders; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Glycoproteins; Insulin; Insulin Secretion; Islets of Langerhans; Maternal-Fetal Exchange; Peptide Hydrolases; Pregnancy; Proteasome Endopeptidase Complex; Protein Array Analysis; Rats; Rats, Wistar; Taurine	2005
Calpastatin overexpression prevents progression of S-1,2-dichlorovinyl-l-cysteine (DCVC)-initiated acute renal injury and renal failure (ARF) in diabetes. Toxicology and applied pharmacology, 2006, Sep-01, Volume: 215, Issue:2 Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antimitotic Agents; Calcium-Binding Proteins; Calpain; Colchicine; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Kidney Function Tests; Kidney Tubules, Proximal; Longevity; Male; Mice; Regeneration	2006
Ischemia promotes calpain-mediated degradation of p120-catenin in SH-SY5Y cells. Biochemical and biophysical research communications, 2007, Feb-16, Volume: 353, Issue:3 Topics: Acetylcysteine; Calpain; Catenins; Cell Adhesion Molecules; Cell Aggregation; Cell Death; Cell Line, Tumor; Delta Catenin; Dipeptides; Humans; Ischemia; Leupeptins; Neuroblastoma; Phosphoproteins	2007
Deciphering the mechanism of HNE-induced apoptosis in cultured murine cortical neurons: transcriptional responses and cellular pathways. Neuropharmacology, 2007, Volume: 53, Issue:5 Topics: Acetylcysteine; Aldehydes; Animals; Apoptosis; Calpain; Caspases; Cell Cycle Proteins; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytoskeleton; Free Radical Scavengers; Gene Expression Regulation; Genes, p53; Mice; Microarray Analysis; Neurons; Oxidative Stress; Signal Transduction; Transcription, Genetic; Ubiquitin	2007
Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells. Blood, 2008, Sep-01, Volume: 112, Issue:5 Topics: Acetylcysteine; Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Antioxidants; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Biological Transport, Active; Calpain; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Dipeptides; Gossypol; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Mitochondrial Membranes; Molecular Mimicry; Reactive Oxygen Species; Superoxides	2008
N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation. Critical care medicine, 2011, Volume: 39, Issue:4 Topics: Acetylcysteine; Animals; Blotting, Western; Calpain; Caspase 3; Diaphragm; Male; Muscle Contraction; Oxidative Stress; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Respiration, Artificial	2011
Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons. Neurotoxicology, 2011, Volume: 32, Issue:6 Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Butadienes; Calpain; Caspase 3; Caspase Inhibitors; Cells, Cultured; Cerebral Cortex; Cysteine Proteinase Inhibitors; Cytoprotection; Dipeptides; Dose-Response Relationship, Drug; Enzyme Activation; Gestational Age; In Situ Nick-End Labeling; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Neuroprotective Agents; Nitriles; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Signal Transduction; Spectrin; Time Factors	2011
Protection of neuronal calcium sensor 1 protein in cells treated with paclitaxel. The Journal of biological chemistry, 2011, Oct-07, Volume: 286, Issue:40 Topics: Acetylcysteine; Calcium Signaling; Calpain; Cell Line, Tumor; Humans; Mutation; Neuroblastoma; Neuronal Calcium-Sensor Proteins; Neurons; Neuropeptides; Paclitaxel; Point Mutation; Protease Inhibitors; Protein Isoforms; Signal Transduction; Thermodynamics	2011
Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model. Neurobiology of disease, 2012, Volume: 45, Issue:3 Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antioxidants; Biophysics; Biotinylation; Calpain; Cell Line, Transformed; Cognition Disorders; Conditioning, Psychological; Cyclin-Dependent Kinase 5; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Fear; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Patch-Clamp Techniques; Peptide Fragments; Presenilin-1; Protein Kinase C-delta; Receptors, Metabotropic Glutamate; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Social Isolation; Time Factors; Transfection	2012
Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation. Particle and fibre toxicology, 2012, Aug-29, Volume: 9 Topics: Acetylcysteine; Air Pollutants; Calcium; Calpain; Cells, Cultured; Electric Impedance; Endothelium, Vascular; Free Radical Scavengers; Humans; Lung; Oxidative Stress; Particulate Matter; Permeability; Reactive Oxygen Species; TRPM Cation Channels; Zonula Occludens-1 Protein	2012
Changes in skeletal muscle proteolytic gene expression after prophylactic supplementation of EGCG and NAC and eccentric damage. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61 Topics: Acetylcysteine; Calpain; Catechin; Dietary Supplements; Double-Blind Method; Exercise; Gene Expression; Humans; Male; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Nontherapeutic Human Experimentation; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Young Adult	2013
The role of intraplatelet reactive oxygen species in the regulation of platelet glycoprotein Ibα ectodomain shedding. Thrombosis research, 2013, Volume: 132, Issue:6 Topics: Acetylcysteine; Blood Platelets; Calcimycin; Calpain; Collagen; Dithiothreitol; Flow Cytometry; Humans; Platelet Glycoprotein GPIb-IX Complex; Reactive Oxygen Species; Thrombin	2013
GSPE is superior to NAC in the prevention of contrast-induced nephropathy: might this superiority be related to caspase 1 and calpain 1? Life sciences, 2014, May-17, Volume: 103, Issue:2 Topics: Acetylcysteine; Animals; Calpain; Caspase 1; Contrast Media; Grape Seed Extract; Kidney Diseases; Male; Proanthocyanidins; Rats; Rats, Sprague-Dawley	2014
Astragaloside IV protects against hyperglycemia-induced vascular endothelial dysfunction by inhibiting oxidative stress and Calpain-1 activation. Life sciences, 2019, Sep-01, Volume: 232 Topics: Acetylcysteine; Animals; Aorta, Thoracic; Biomarkers; Calpain; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Experimental; Dipeptides; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saponins; Streptozocin; Triterpenes; Vasodilation	2019
N-acetyl cysteine inhibits IL-1α release from murine keratinocytes induced by 2-hydroxyethyl methacrylate. The Journal of toxicological sciences, 2023, Volume: 48, Issue:10 Topics: Acetylcysteine; Animals; Calpain; Inflammation; Keratinocytes; Methacrylates; Mice; Reactive Oxygen Species	2023