acetylcysteine and cadmium

acetylcysteine has been researched along with cadmium in 90 studies

Research

Studies (90)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.22)18.7374
1990's6 (6.67)18.2507
2000's25 (27.78)29.6817
2010's41 (45.56)24.3611
2020's16 (17.78)2.80

Authors

AuthorsStudies
Ottenwälder, H; Simon, P1
Kägi, JH; Pande, J; Vasák, M1
Hirata, D; Miyakawa, T; Yano, K1
Brennan, RJ; Schiestl, RH1
Abe, T; Gotoh, S; Higashi, K; Kashimura, M; Yamamura, K1
Igisu, H; Matsuno, K; Matsuoka, M; Wispriyono, B1
Shaikh, ZA; Vu, TT; Zaman, K1
Harvey, I; Li, H; Sadler, PJ; Sun, H1
Almazan, G; Chemtob, S; Khorchid, A; Liu, HN; Martinez-Bermudez, AK; Sundararajan, S1
Amano, S; Eguchi, Y; Fukui, K; Hirata, K; Imanaka, T; Miyamoto, K; Mizuno, H; Satofuka, H; Takagi, M1
Figueiredo-Pereira, ME; Jansen, M; Li, Z; Rockwell, P1
Bachelet, M; François, D; Pinot, F; Polla, BS; Polla, RI; Richard, MJ; Vayssier-Taussat, M1
Maki, D; Stapleton, SR; Xu, J1
Bodo, CC; Cabilla, JP; Duvilanski, BH; Poliandri, AH; Velardez, MO1
de Sousa, G; Orsini, N; Rahmani, R; Risso-de Faverney, C1
Jarosz-Wilkołazka, A; Staszczak, M1
Lim, SC; Oh, SH1
Huang, D; Liu, J; Song, G; Zhang, Y1
Khandelwal, S; Pathak, N1
Johnson, VJ; Kim, J; Kim, SH; Sharma, RP1
Aller, P; Amrán, D; de Blas, E; Fernández, C; Ramos, AM; Sancho, P; Susin, SA; Yuste, VJ1
Evangelinos, N; Kaloyianni, M; Koliakos, G; Koutsogiannaki, S1
Adachi, Y; Andoh, Y; Ikehara, S; Ishii, T; Kojo, S; Mizutani, A; Ohashi, T; Taketani, S1
Pat, SW; Yang, MS; Yu, LC1
Dabarakis, N; Geronikaki, A; Kaloyianni, M; Kosmidis, EK; Moschou, M; Theophilidis, G1
Avery, SV; Houghton, JE; Nargund, AM1
Berglund, T; Greger, M; Landberg, T; Ohlsson, AB1
Hong, SH; Jeong, HJ; Kim, HM; Kim, MC; Kim, SJ; Lee, JH; Myung, NY; Park, RK; So, HS; Um, JY1
Chen, L; Huang, S; Liu, L1
Hsiao, CJ; Stapleton, SR1
Ko, WC; Kuo, TC; Shih, CM; Shih, YL; Wang, SH1
Antonopoulou, E; Papaefthimiou, C; Theophilidis, G1
Cao, J; Chen, D; Liu, Z; Wang, L1
Balasubramanian, I; Bannigan, J; Doi, T; Power, E; Puri, P; Thompson, J1
Antes, FG; Bochi, GV; Dressler, VL; Fiorenza, AM; Gonçalves, JF; Mazzanti, CM; Morsch, VM; Rubin, MA; Schetinger, MR; Spanevello, RM; Stefanello, N1
Deng, X; Hu, W; Shen, Z; Xia, Y; Zhang, H1
Badisa, RB; Badisa, VL; Darling-Reed, SF; Ikediobi, CO; Latinwo, LM; Le, UT; Odewumi, CO1
Chen, L; Chen, W; Han, X; Huang, S; Kontos, CD; Liu, L; Luo, Y; Shen, T; Xu, B; Zhou, H1
Chi, Y; Fang, X; Huang, T; Jiang, JX; Kitamura, M; Matsue, H; Wang, P; Yan, Q; Yao, J; Zhu, Y1
Chen, D; Li, J; Liu, Z; Wang, H; Wang, L1
Karayakar, F; Karaytug, S; Sevgiler, Y2
Baek, BJ; Cho, MK; Heo, SH; Im, JH; Lee, GJ; Lee, SH; Lee, YJ; Nam, HS; Won, SY1
Amini, Z; Jalilehvand, F; Kang, EY; Parmar, K1
Emilio, R; Mahara, V; Martín, SA1
Chen, HC; Li, MH; Wu, JP1
Li, J; Shen, Q; Wang, F; Wang, J; Wang, L; Wang, Q1
Gailer, J; Zeini Jahromi, E1
Abdalla, FH; Antes, FG; Bagatini, MD; Costa, P; Dressler, VL; Duarte, MM; Fiorenza, AM; Gonçalves, JF; Mazzanti, CM; Morsch, VM; Schetinger, MR; Schmatz, R; Spanevello, RM1
Abdalla, FH; Bagatini, MD; Becker, LV; da Costa, P; da Rosa, CS; Fiorenza, AM; Gonçalves, JF; Mazzanti, CM; Morsch, VM; Schetinger, MR; Spanevello, RM1
Cheon, HS; Juhnn, YS; Kim, S; Kim, SY; Kim, YY1
Chen, YH; Ji, YL; Wang, H; Xu, DX; Zhang, C; Zhang, Y; Zhao, M1
Chenyang, J; Jiajing, W; Jianchun, B; Jianhong, G; Xuezhong, L; Yan, Y; Yiran, Z; Zongping, L1
Chen, YC; Ho, CC; Lin, P; Lin, SY; Luo, YH; Tsai, MH; Wei, YH; Wu, SB; Yang, CS1
Luczak, MW; Zhitkovich, A1
Li, C; Wang, Q; Yu, X; Zhan, G1
Chen, L; Chen, S; Gao, W; Gu, C; Guo, M; Huang, S; Ji, H; Ren, Q; Xu, C; Xu, Y; Ye, Y; Zhang, J; Zhang, Z1
Bahl, N; Boshart, SJ; Gailer, J; Keir, JL; Lobanov, VP; Morris, TT; Ruhland, AM1
Alaie, SH; Panjehpour, M1
Barajas-Espinosa, A; Basye, A; Chen, CA; Jesse, E; Quan, D; Yan, H1
Liu, X; Liu, Z; Wang, J; Zhu, H1
Cai, H; Gu, X; Qi, Y; Wei, X; Yang, J; Zhang, X; Zhang, Y1
Khandelwal, S; Khanna, S; Lakhera, PC; Mitra, S1
Bian, J; Gu, J; Liu, X; Liu, Z; Song, R; Wang, Q; Wang, T; Yuan, Y; Zhang, K; Zhang, Y1
Bian, JC; Gu, JH; Liu, XZ; Liu, ZP; Wang, QW; Wang, T; Wang, Y; Yuan, Y; Zhang, KB; Zhu, JQ1
Chun, B; Gu, J; Liu, X; Liu, Z; Wang, J; Wang, Y; Yan, Y; Zhang, Y1
Oh, SH; So, KY1
Li, C; Li, M; Tan, Y; Wang, Y; Wu, T; Ye, X1
Jung, KT; Kim, SH; Lee, HY; Oh, SH; So, KY1
Chen, YH; Guo, MY; Wang, H; Xia, MZ; Xu, DX; Zhang, C1
Gabriel, C; Hatzidimitriou, A; Iordanidou, C; Salifoglou, A; Tsave, O1
Miyamoto, A; Shiraishi, M; Sudo, K; VAN Dao, C1
Dolezel, P; Kikalova, K; Maier, V; Mlejnek, P; Skoupa, N1
Cao, H; Dai, X; Hu, G; Nie, G; Xing, C; Yang, F; Zhang, C; Zhuang, J1
Hu, X; Li, Y; Ren, X; Wang, S; Xu, L; Zhang, C; Zhou, L1
Beigi Harchegani, A; Rahmani Talatappeh, N; Ranji, N1
Alizadeh, B; Arasteh, A; Ranji, N; Salehzadeh, A1
Azarmehr, Z; Habibollahi, H; Khazaei Koohpar, Z; Ranji, N1
Hirota, K; Matsuoka, M1
Beigi Harchegani, A; Jaafarzadeh, M; Mahjoob Khaligh, R; Mohsenifar, Z; Rajabi Keleshteri, S; Rezvani Gilkalaei, M; Shabani, A1
Aparna, Y; Kandukuri, V; Madduru, R; Motireddy, SR; Poli, V1
Chen, D; Hu, B; Jin, X; Qian, X; Tang, J; Xu, G; Xu, L; Zhang, Y1
Rathinasabapathi, B; Shaheen, H; Tahir, MA1
Huang, YC; Liu, WB; Lv, J; Wang, H; Xiong, YW; Zhu, HL1
Lin, R; Pian, Y; Ren, X; Zhang, C; Zhou, L1
Abdel-Daim, MM; Ahmed, OS; Hassanein, EHM; Mohamed, WR; Sayed, AM1
Anderegg, U; Bauer, M; Fink, B; Röder, S; Zenclussen, AC1
Dong, W; Gong, Z; Li, J; Liu, G; Liu, Z; Luo, T; Ma, Y; Song, R; Wang, X; Zhang, K; Zhu, J; Zou, H1
Gui, M; Huang, W; Jin, X; Li, P; Wu, P; Xiong, C1
Demirbas, A; Dik, B; Gungor, H; Korkmaz, Y1

Reviews

1 review(s) available for acetylcysteine and cadmium

ArticleYear
The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view.
    Life sciences, 2022, Nov-01, Volume: 308

    Topics: Acetylcysteine; Cadmium; Cytochalasin D; Cytokines; Humans; Inflammation; Kidney Diseases; NF-kappa B; Polysaccharides; Sildenafil Citrate; Telmisartan

2022

Other Studies

89 other study(ies) available for acetylcysteine and cadmium

ArticleYear
Differential effect of N-acetylcysteine on excretion of the metals Hg, Cd, Pb and Au.
    Archives of toxicology, 1987, Volume: 60, Issue:5

    Topics: Acetylcysteine; Animals; Cadmium; Feces; Gold; Lead; Male; Mercury; Metals; Rats; Rats, Inbred Strains

1987
Interaction of lysine residues with the metal thiolate clusters in metallothionein.
    Biochemistry, 1985, Nov-05, Volume: 24, Issue:23

    Topics: Acetylcysteine; Amino Acids; Animals; Cadmium; Circular Dichroism; Edetic Acid; Kinetics; Liver; Lysine; Metallothionein; Nitrobenzenes; Protein Conformation; Rats; Trinitrobenzenesulfonic Acid; Zinc

1985
Stress-induced transcriptional activation mediated by YAP1 and YAP2 genes that encode the Jun family of transcriptional activators in Saccharomyces cerevisiae.
    Molecular & general genetics : MGG, 1994, Volume: 242, Issue:3

    Topics: Acetylcysteine; Amino Acid Sequence; Base Sequence; Cadmium; DNA-Binding Proteins; DNA, Fungal; Fungal Proteins; Genes, Fungal; Molecular Sequence Data; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Regulatory Sequences, Nucleic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Transcriptional Activation

1994
Cadmium is an inducer of oxidative stress in yeast.
    Mutation research, 1996, Sep-23, Volume: 356, Issue:2

    Topics: Acetylcysteine; Anaerobiosis; Cadmium; Culture Media; Fluorescence; Glutamate-Cysteine Ligase; Methyl Methanesulfonate; Mutagenesis; Oxidative Stress; Oxygen; Recombination, Genetic; Saccharomyces cerevisiae; Superoxide Dismutase

1996
Concentration-dependent differential effects of N-acetyl-L-cysteine on the expression of HSP70 and metallothionein genes induced by cadmium in human amniotic cells.
    Biochimica et biophysica acta, 1998, Mar-12, Volume: 1380, Issue:1

    Topics: Acetylcysteine; Amnion; Cadmium; Cell Line; Dose-Response Relationship, Drug; Gene Expression; Glutathione; HSP70 Heat-Shock Proteins; Humans; Lipid Peroxidation; Metallothionein; RNA, Messenger

1998
Protection from cadmium cytotoxicity by N-acetylcysteine in LLC-PK1 cells.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cadmium; Cell Survival; Dactinomycin; Glutathione; Kidney; LLC-PK1 Cells; Proto-Oncogene Proteins c-fos; Swine

1998
Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants.
    Toxicology and applied pharmacology, 1999, Feb-01, Volume: 154, Issue:3

    Topics: Acetylcysteine; Alanine Transaminase; Amitrole; Animals; Anti-Inflammatory Agents; Antioxidants; Buthionine Sulfoximine; Cadmium; Cysteine; Drug Combinations; Enzyme Inhibitors; Female; Glutathione; Glycine; Glycyrrhetinic Acid; Kidney; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Malondialdehyde; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Steroids; Time Factors; Vitamin E

1999
Interactions of bismuth complexes with metallothionein(II).
    The Journal of biological chemistry, 1999, Oct-08, Volume: 274, Issue:41

    Topics: Acetylcysteine; Animals; Anti-Ulcer Agents; Binding, Competitive; Bismuth; Cadmium; Glutathione; Kinetics; Magnetic Resonance Spectroscopy; Metallothionein; Organometallic Compounds; Protein Binding; Rabbits; Spectrum Analysis; Zinc

1999
Exposure of developing oligodendrocytes to cadmium causes HSP72 induction, free radical generation, reduction in glutathione levels, and cell death.
    Free radical biology & medicine, 2000, Nov-01, Volume: 29, Issue:9

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cadmium; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Free Radicals; Glutathione; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Oligodendroglia; Oxidative Stress; Rats

2000
Cellular toxicity of cadmium ions and their detoxification by heavy metal-specific plant peptides, phytochelatins, expressed in Mammalian cells.
    Journal of biochemistry, 2002, Volume: 131, Issue:2

    Topics: Acetylcysteine; Aminoacyltransferases; Apoptosis; Blotting, Western; Cadmium; Cell Nucleus; Cells, Cultured; Chelating Agents; DNA Primers; Drug Resistance; Free Radical Scavengers; Glutathione; Humans; Inactivation, Metabolic; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 4; Metalloproteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phytochelatins; Plants; Plasmids; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Time Factors; Transfection

2002
N-acetylcysteine and celecoxib lessen cadmium cytotoxicity which is associated with cyclooxygenase-2 up-regulation in mouse neuronal cells.
    The Journal of biological chemistry, 2002, Jul-12, Volume: 277, Issue:28

    Topics: Acetylcysteine; Animals; Antioxidants; Base Sequence; Cadmium; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine Endopeptidases; Dinoprostone; DNA Primers; Isoenzymes; Mice; Multienzyme Complexes; Neurons; Prostaglandin-Endoperoxide Synthases; Proteasome Endopeptidase Complex; Pyrazoles; Sulfonamides; Tumor Cells, Cultured; Ubiquitin; Up-Regulation

2002
Toxicity of cadmium in tobacco smoke: protection by antioxidants and chelating resins.
    Free radical research, 2002, Volume: 36, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphate; Anions; Antioxidants; Cadmium; Cadmium Chloride; Cation Exchange Resins; Cell Death; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Flow Cytometry; Free Radical Scavengers; Glutathione; HSP70 Heat-Shock Proteins; Humans; Microscopy, Immunoelectron; Monocytes; Necrosis; Reactive Oxygen Species; Resins, Synthetic; Smoking; Superoxides; Time Factors

2002
Mediation of cadmium-induced oxidative damage and glucose-6-phosphate dehydrogenase expression through glutathione depletion.
    Journal of biochemical and molecular toxicology, 2003, Volume: 17, Issue:2

    Topics: Acetylcysteine; Animals; Blotting, Northern; Buthionine Sulfoximine; Cadmium; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Glutathione; Hepatocytes; L-Lactate Dehydrogenase; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger

2003
Cadmium induces apoptosis in anterior pituitary cells that can be reversed by treatment with antioxidants.
    Toxicology and applied pharmacology, 2003, Jul-01, Volume: 190, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cadmium; Caspases; Cell Survival; Chromans; DNA Fragmentation; Free Radical Scavengers; Hormones; Immunohistochemistry; Male; Oxidative Stress; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Vitamin E

2003
Cadmium-induced apoptosis through the mitochondrial pathway in rainbow trout hepatocytes: involvement of oxidative stress.
    Aquatic toxicology (Amsterdam, Netherlands), 2004, Aug-25, Volume: 69, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cadmium; Caspases; Cyclic N-Oxides; Cytochromes c; Dose-Response Relationship, Drug; Hepatocytes; Mitochondria; Oncorhynchus mykiss; Oxidative Stress; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Statistics, Nonparametric; Time Factors

2004
Inhibition of the proteasome strongly affects cadmium stimulated laccase activity in Trametes versicolor.
    Biochimie, 2005, Volume: 87, Issue:8

    Topics: Acetylcysteine; Cadmium; Chloroquine; Dose-Response Relationship, Drug; Fungal Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Laccase; Leupeptins; Mycelium; Proteasome Endopeptidase Complex; Proteasome Inhibitors

2005
A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation.
    Toxicology and applied pharmacology, 2006, May-01, Volume: 212, Issue:3

    Topics: Acetylcysteine; Apoptosis; Cadmium; Carcinoma, Hepatocellular; Caspases; Catalase; Cell Line; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Combinations; Environmental Pollutants; fas Receptor; Humans; In Situ Nick-End Labeling; Membrane Potentials; Mitochondria, Liver; Reactive Oxygen Species; Signal Transduction; Up-Regulation

2006
Cadmium induced MTs synthesis via oxidative stress in yeast Saccharomyces cerevisiae.
    Molecular and cellular biochemistry, 2005, Volume: 280, Issue:1-2

    Topics: Acetylcysteine; Cadmium; Catalase; Cell Survival; Glutathione Peroxidase; Lipid Peroxidation; Malondialdehyde; Metallothionein; Oxidative Stress; Saccharomyces cerevisiae; Superoxide Dismutase

2005
Oxidative stress and apoptotic changes in murine splenocytes exposed to cadmium.
    Toxicology, 2006, Mar-01, Volume: 220, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; Cadmium; Caspase 3; Caspases; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Combinations; Environmental Pollutants; G1 Phase; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondrial Membranes; Necrosis; Oxidative Stress; Pyrrolidines; Spleen; Thiocarbamates

2006
Extracellular signal-regulated kinase-signaling-dependent G2/M arrest and cell death in murine macrophages by cadmium.
    Environmental toxicology and chemistry, 2005, Volume: 24, Issue:12

    Topics: Acetylcysteine; Animals; Cadmium; Cadmium Chloride; Caspase 3; Caspases; Cell Cycle; Cell Death; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; DNA; Extracellular Signal-Regulated MAP Kinases; G2 Phase; Macrophages; Mice; Mice, Inbred BALB C; Necrosis; Phosphorylation; Reactive Oxygen Species; Time Factors

2005
Regulation of apoptosis/necrosis execution in cadmium-treated human promonocytic cells under different forms of oxidative stress.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:5

    Topics: Acetylcysteine; Adenosine Triphosphate; Antimetabolites, Antineoplastic; Apoptosis; Benzamides; Buthionine Sulfoximine; Cadmium; Caspase 3; Caspase 9; Caspases; Drug Interactions; Glutathione; Humans; Hydrogen Peroxide; Membrane Potentials; Mitochondria; Monocytes; Necrosis; Oxidants; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Transfection; U937 Cells

2006
Cytotoxic mechanisms of Zn2+ and Cd2+ involve Na+/H+ exchanger (NHE) activation by ROS.
    Aquatic toxicology (Amsterdam, Netherlands), 2006, Jul-20, Volume: 78, Issue:4

    Topics: Acetylcysteine; Amiloride; Animals; Antimycin A; Antioxidants; Cadmium; Cadmium Poisoning; Cell Survival; Gills; Hydrogen-Ion Concentration; Mytilus; Naphthalenes; Oxidants; PPAR gamma; Protein Kinase Inhibitors; Pyruvic Acid; Reactive Oxygen Species; Receptors, Adrenergic; Rosiglitazone; Rotenone; Sodium-Hydrogen Exchangers; Thiazolidinediones; Water Pollutants, Chemical; Zinc

2006
The antioxidant role of a reagent, 2',7'-dichlorodihydrofluorescin diacetate, detecting reactive-oxygen species and blocking the induction of heme oxygenase-1 and preventing cytotoxicity.
    Journal of biochemistry, 2006, Volume: 140, Issue:4

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Antioxidants; Arsenites; Cadmium; Cell Nucleus; Cell Survival; Cytoprotection; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Fluoresceins; HeLa Cells; Heme Oxygenase-1; Hemin; Humans; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Promoter Regions, Genetic; Reactive Oxygen Species

2006
Manipulation of energy and redox states in the C6 glioma cells by buthionine sulfoxamine and N-acetylcysteine and the effect on cell survival to cadmium toxicity.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, Apr-15, Volume: 53, Issue:1

    Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cadmium; Cell Line, Tumor; Cell Survival; Energy Metabolism; Glutathione; Glutathione Disulfide; Humans; Oxidation-Reduction; Rats

2007
In vitro assessment of the neurotoxic and neuroprotective effects of N-acetyl-L-cysteine (NAC) on the rat sciatic nerve fibers.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:1

    Topics: Acetylcysteine; Action Potentials; Animals; Cadmium; Dose-Response Relationship, Drug; Free Radical Scavengers; In Vitro Techniques; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Sciatic Nerve; Sodium Channels; Time Factors

2008
Cadmium induces a heterogeneous and caspase-dependent apoptotic response in Saccharomyces cerevisiae.
    Apoptosis : an international journal on programmed cell death, 2008, Volume: 13, Issue:6

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Cadmium; Caspases; Cell Membrane Permeability; Enzyme Induction; Glutathione; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mutation; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2008
Increased metal tolerance in Salix by nicotinamide and nicotinic acid.
    Plant physiology and biochemistry : PPB, 2008, Volume: 46, Issue:7

    Topics: Acetylcysteine; Adaptation, Physiological; Analysis of Variance; Buthionine Sulfoximine; Cadmium; Chromatography, High Pressure Liquid; Copper; Enzyme Inhibitors; Glutathione; Metals; Niacin; Niacinamide; Pyrrolidonecarboxylic Acid; Salix; Thiazolidines; Zinc

2008
The protective mechanism of antioxidants in cadmium-induced ototoxicity in vitro and in vivo.
    Environmental health perspectives, 2008, Volume: 116, Issue:7

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cadmium; Caspases; Cell Line; Cell Survival; Cochlear Diseases; Environmental Pollutants; Humans; Male; Mice; Mice, Inbred C57BL; Organ of Corti; Oxidative Stress; Reactive Oxygen Species

2008
Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5.
    Free radical biology & medicine, 2008, Oct-01, Volume: 45, Issue:7

    Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Cadmium; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Free Radical Scavengers; Humans; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphoprotein Phosphatases; Protein Phosphatase 2; Rats; Reactive Oxygen Species; Signal Transduction

2008
Early sensing and gene expression profiling under a low dose of cadmium exposure.
    Biochimie, 2009, Volume: 91, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Buthionine Sulfoximine; Cadmium; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Gene Expression Profiling; Hepatocytes; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors

2009
Cadmium toxicity toward autophagy through ROS-activated GSK-3beta in mesangial cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 108, Issue:1

    Topics: Acetylcysteine; Analysis of Variance; Animals; Autophagy; Cadmium; Cell Line; Gene Expression; Gene Knockdown Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Maleimides; Mesangial Cells; Mice; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction

2009
Inhibitory vs. protective effects of N-acetyl-l-cysteine (NAC) on the electromechanical properties of the spontaneously beating atria of the frog (Rana ridibunda): an ex vivo study.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:2

    Topics: Acetylcysteine; Action Potentials; Animals; Atrial Function; Cadmium; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Female; Free Radical Scavengers; Heart Atria; In Vitro Techniques; Male; Myocytes, Cardiac; No-Observed-Adverse-Effect Level; Rana ridibunda; Rotenone

2009
Protective effect of N-acetylcysteine on experimental chronic cadmium nephrotoxicity in immature female rats.
    Human & experimental toxicology, 2009, Volume: 28, Issue:4

    Topics: Acetylcysteine; Animals; Biomarkers; Body Weight; Cadmium; Enzymes; Female; Free Radical Scavengers; Kidney Cortex; Kidney Diseases; Lipid Peroxidation; Oxidative Stress; Protective Agents; Proteinuria; Rats; Rats, Sprague-Dawley; Trace Elements; Urodynamics

2009
Evidence against a direct role for oxidative stress in cadmium-induced axial malformation in the chick embryo.
    Toxicology and applied pharmacology, 2010, Mar-15, Volume: 243, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetylcysteine; Animals; Antioxidants; Body Patterning; Cadmium; Catalase; Chick Embryo; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Hydrogen-Ion Concentration; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA; Superoxide Dismutase; Teratogens

2010
N-acetylcysteine prevents memory deficits, the decrease in acetylcholinesterase activity and oxidative stress in rats exposed to cadmium.
    Chemico-biological interactions, 2010, Jun-07, Volume: 186, Issue:1

    Topics: Acetylcholinesterase; Acetylcysteine; Animals; Antioxidants; Behavior, Animal; Brain; Cadmium; Creatinine; Lipid Peroxidation; Male; Memory Disorders; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Urea

2010
Cadmium-induced oxidative damage and protective effects of N-acetyl-L-cysteine against cadmium toxicity in Solanum nigrum L.
    Journal of hazardous materials, 2010, Aug-15, Volume: 180, Issue:1-3

    Topics: Acetylcysteine; Cadmium; Enzymes; Lipid Peroxidation; Oxidative Stress; Solanum nigrum; Thiobarbituric Acid Reactive Substances

2010
Protective effects of N-acetylcysteine against cadmium-induced damage in cultured rat normal liver cells.
    International journal of molecular medicine, 2011, Volume: 27, Issue:2

    Topics: Acetylcysteine; Animals; Cadmium; Catalase; Cell Cycle; Cell Line; Cell Survival; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Reductase; Hepatocytes; Rats

2011
Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death.
    Free radical biology & medicine, 2011, Mar-01, Volume: 50, Issue:5

    Topics: Acetylcysteine; Androstadienes; Animals; Apoptosis; Cadmium; Carrier Proteins; Environmental Pollutants; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; NADPH Oxidases; Neurodegenerative Diseases; Neurons; PC12 Cells; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; Receptors, Somatomedin; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases; Wortmannin

2011
Connexin43 hemichannels contribute to cadmium-induced oxidative stress and cell injury.
    Antioxidants & redox signaling, 2011, Jun-15, Volume: 14, Issue:12

    Topics: Acetylcysteine; Animals; Cadmium; Cell Line; Connexin 43; Fibroblasts; Gap Junctions; Glutathione; Mice; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; RNA, Small Interfering; Swine

2011
Simultaneous effects of lead and cadmium on primary cultures of rat proximal tubular cells: interaction of apoptosis and oxidative stress.
    Archives of environmental contamination and toxicology, 2011, Volume: 61, Issue:3

    Topics: Acetates; Acetylcysteine; Adenosine Triphosphatases; Animals; Apoptosis; Cadmium; Calcium; Cell Survival; Cells, Cultured; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lead; Lipid Peroxidation; Malondialdehyde; Membrane Potential, Mitochondrial; Necrosis; Organometallic Compounds; Oxidative Stress; Rats; Reactive Oxygen Species

2011
Antioxidative effects of N-acetylcysteine, lipoic acid, taurine, and curcumin in the muscle of Cyprinus carpio L. exposed to cadmium.
    Arhiv za higijenu rada i toksikologiju, 2011, Volume: 62, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Carps; Catalase; Curcumin; Enzyme Inhibitors; Free Radical Scavengers; Glutathione Disulfide; Glutathione Peroxidase; Lipid Peroxidation; Muscle, Skeletal; Oxidative Stress; Superoxide Dismutase; Taurine; Thioctic Acid

2011
Cadmium-induced up-regulation of aldo-keto reductase 1C3 expression in human nasal septum carcinoma RPMI-2650 cells: Involvement of reactive oxygen species and phosphatidylinositol 3-kinase/Akt.
    Environmental toxicology and pharmacology, 2011, Volume: 31, Issue:3

    Topics: Acetylcysteine; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Antioxidants; Blotting, Western; Cadmium; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Enzymologic; Humans; Indicators and Reagents; NF-E2-Related Factor 2; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Up-Regulation

2011
Comparison of the protective effects of antioxidant compounds in the liver and kidney of Cd- and Cr-exposed common carp.
    Environmental toxicology, 2014, Volume: 29, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Carps; Catalase; Chromium; Curcumin; Glutathione; Kidney; Lipid Peroxidation; Liver; Oxidative Stress; Superoxide Dismutase; Taurine; Thioctic Acid; Water Pollutants, Chemical

2014
Cadmium(II) N-acetylcysteine complex formation in aqueous solution.
    Dalton transactions (Cambridge, England : 2003), 2011, Dec-21, Volume: 40, Issue:47

    Topics: Acetylcysteine; Cadmium; Coordination Complexes; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Water; X-Ray Absorption Spectroscopy

2011
Role of oxidative stress in transformation induced by metal mixture.
    Oxidative medicine and cellular longevity, 2011, Volume: 2011

    Topics: Acetylcysteine; Air Pollutants; Animals; Arsenic; BALB 3T3 Cells; Cadmium; Carcinogens, Environmental; Cell Survival; Cell Transformation, Neoplastic; Free Radical Scavengers; Humans; Lead; Mice; Oxidative Stress; Reactive Oxygen Species

2011
Bioaccumulation and toxicodynamics of cadmium to freshwater planarian and the protective effect of N-acetylcysteine.
    Archives of environmental contamination and toxicology, 2012, Volume: 63, Issue:2

    Topics: Acetylcysteine; Animals; Cadmium; Free Radical Scavengers; Models, Animal; Oxidative Stress; Planarians; Random Allocation; Toxicity Tests, Acute; Water Pollutants, Chemical

2012
Cadmium induces hydrogen peroxide production and initiates hydrogen peroxide-dependent apoptosis in the gill of freshwater crab, Sinopotamon henanense.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2012, Volume: 156, Issue:3-4

    Topics: Acetylcysteine; Animals; Apoptosis; Biomarkers; Brachyura; Cadmium; Caspase 3; Caspase 9; Caspase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Gills; Hydrogen Peroxide; Male; Microscopy, Electron, Transmission; Reactive Oxygen Species; Thiourea; Time Factors; Toxicity Tests

2012
In vitro assessment of chelating agents with regard to their abstraction efficiency of Cd(2+) bound to plasma proteins.
    Metallomics : integrated biometal science, 2012, Volume: 4, Issue:9

    Topics: Acetylcysteine; Animals; Blood Proteins; Cadmium; Calcium; Chelating Agents; Chromatography, Gel; Humans; Rabbits; Spectrophotometry, Atomic; Succimer; Unithiol; Zinc

2012
Hematological indices and activity of NTPDase and cholinesterase enzymes in rats exposed to cadmium and treated with N-acetylcysteine.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2012, Volume: 25, Issue:6

    Topics: Acetylcholinesterase; Acetylcysteine; Animals; Antigens, CD; Apyrase; Butyrylcholinesterase; Cadmium; Lymphocytes; Male; Rats; Rats, Wistar; Structure-Activity Relationship

2012
NTPDase and 5'-nucleotidase activities from synaptosomes and platelets of rats exposed to cadmium and treated with N-acetylcysteine.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2013, Volume: 31, Issue:1

    Topics: 5'-Nucleotidase; Acetylcysteine; Analysis of Variance; Animals; Blood Platelets; Brain; Cadmium; Free Radical Scavengers; Male; Pyrophosphatases; Rats; Rats, Wistar; Synaptosomes

2013
Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153.
    BMC cell biology, 2013, Jan-22, Volume: 14

    Topics: Acetylcysteine; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cadmium; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Free Radical Scavengers; Humans; Neurons; Promoter Regions, Genetic; Protein Binding; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Transcription Factor CHOP

2013
N-acetylcysteine protects against cadmium-induced germ cell apoptosis by inhibiting endoplasmic reticulum stress in testes.
    Asian journal of andrology, 2013, Volume: 15, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cadmium; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glutathione; Heat-Shock Proteins; Heme Oxygenase-1; Male; Membrane Proteins; Mice; Models, Biological; RNA, Messenger; Spermatozoa; Testis; Unfolded Protein Response

2013
Oxidative stress and mitogen-activated protein kinase pathways involved in cadmium-induced BRL 3A cell apoptosis.
    Oxidative medicine and cellular longevity, 2013, Volume: 2013

    Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Butadienes; Cadmium; Cell Line; Extracellular Signal-Regulated MAP Kinases; Glutathione Peroxidase; Imidazoles; JNK Mitogen-Activated Protein Kinases; Malondialdehyde; Mitogen-Activated Protein Kinases; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase

2013
Cadmium-based quantum dot induced autophagy formation for cell survival via oxidative stress.
    Chemical research in toxicology, 2013, May-20, Volume: 26, Issue:5

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Autophagy; Cadmium; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Metal Nanoparticles; Mice; Mitochondria; Oxidative Stress; Quantum Dots; Reactive Oxygen Species; Structure-Activity Relationship; Tumor Cells, Cultured

2013
Role of direct reactivity with metals in chemoprotection by N-acetylcysteine against chromium(VI), cadmium(II), and cobalt(II).
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Acetylcysteine; Antioxidants; Blotting, Western; Cadmium; Cell Line; Chromium; Cobalt; Cytoprotection; Humans; Oxidative Stress

2013
Fluorescent sensor for selective determination of copper ion based on N-acetyl-L-cysteine capped CdHgSe quantum dots.
    Biosensors & bioelectronics, 2014, Apr-15, Volume: 54

    Topics: Acetylcysteine; Cadmium; Cations, Divalent; Copper; Fluorescent Dyes; Lakes; Limit of Detection; Mercury; Quantum Dots; Selenium; Spectrometry, Fluorescence

2014
N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain.
    Neuropathology and applied neurobiology, 2014, Volume: 40, Issue:6

    Topics: Acetylcysteine; Animals; Apoptosis; Brain; Cadmium; Male; Mice; Mice, Inbred ICR; Neurons; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases

2014
Mobilization of Cd from human serum albumin by small molecular weight thiols.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, May-01, Volume: 958

    Topics: Acetylcysteine; Cadmium; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Humans; Protein Binding; Serum Albumin; Sulfhydryl Compounds

2014
N-acetylcysteine prevents cadmium-induced apoptosis in human breast cancer MDA-MB468 cell line.
    Cellular and molecular biology (Noisy-le-Grand, France), 2014, May-11, Volume: 60, Issue:1

    Topics: Acetylcysteine; Apoptosis; Breast Neoplasms; Cadmium; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Female; Humans; Oxidative Stress; Protective Agents; Reactive Oxygen Species

2014
Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd²⁺-induced apoptosis.
    Free radical biology & medicine, 2014, Volume: 74

    Topics: Acetylcysteine; Animals; Apoptosis; Cadmium; Cattle; Cell Growth Processes; Cell Line; Cell Survival; Cytoprotection; Dual-Specificity Phosphatases; Endothelial Cells; Glutathione; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Phosphatases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Rats; RNA, Small Interfering; Up-Regulation

2014
N-acetylcysteine protects against cadmium-induced oxidative stress in rat hepatocytes.
    Journal of veterinary science, 2014, Volume: 15, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Cell Survival; Cells, Cultured; Environmental Pollutants; Hepatocytes; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2014
ROS act as an upstream signal to mediate cadmium-induced mitophagy in mouse brain.
    Neurotoxicology, 2015, Volume: 46

    Topics: Acetylcarnitine; Acetylcysteine; Analysis of Variance; Animals; Brain; Cadmium; Collagenases; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Microscopy, Electron, Transmission; Microtubule Proteins; Microtubule-Associated Proteins; Mitochondrial Diseases; Reactive Oxygen Species; Signal Transduction; Ubiquitin-Protein Ligases

2015
N-acetylcysteine effectively mitigates cadmium-induced oxidative damage and cell death in Leydig cells in vitro.
    Drug and chemical toxicology, 2016, Volume: 39, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cadmium; Calcium; Cell Death; Glutathione; Leydig Cells; Male; Mitochondrial Membranes; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors

2016
Autophagy Plays a Cytoprotective Role During Cadmium-Induced Oxidative Damage in Primary Neuronal Cultures.
    Biological trace element research, 2015, Volume: 168, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Autophagy; Cadmium; Cells, Cultured; Cerebral Cortex; Chloroquine; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Microtubule-Associated Proteins; Neurons; Oxidative Stress; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2015
Cadmium-induced autophagy is mediated by oxidative signaling in PC-12 cells and is associated with cytoprotection.
    Molecular medicine reports, 2015, Volume: 12, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Autophagy; Cadmium; Cytoprotection; Environmental Pollutants; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Signal Transduction

2015
Investigation of cadmium-induced apoptosis and the protective effect of N-acetylcysteine in BRL 3A cells.
    Molecular medicine reports, 2016, Volume: 14, Issue:1

    Topics: Acetates; Acetylcysteine; Animals; Apoptosis; Cadmium; Caspase 3; Caspase 8; Caspase 9; Cell Line, Transformed; Free Radical Scavengers; Membrane Potential, Mitochondrial; Mitochondria; Poly(ADP-ribose) Polymerases; Rats

2016
Cadmium-induced heme-oxygenase-1 expression plays dual roles in autophagy and apoptosis and is regulated by both PKC-δ and PKB/Akt activation in NRK52E kidney cells.
    Toxicology, 2016, Aug-31, Volume: 370

    Topics: Acetylcysteine; Animals; Apoptosis; Autophagy; Cadmium; Cell Line, Tumor; Cell Survival; DNA Damage; Eukaryotic Initiation Factor-2; Glycogen Synthase Kinase 3; Heme Oxygenase (Decyclizing); Inhibitory Concentration 50; Kidney; Oxidative Stress; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Protein Kinase C-delta; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Transcription Factor CHOP; Up-Regulation

2016
Enhanced photoelectrochemical immunosensing of cardiac troponin I based on energy transfer between N-acetyl-L-cysteine capped CdAgTe quantum dots and dodecahedral Au nanoparticles.
    Biosensors & bioelectronics, 2017, May-15, Volume: 91

    Topics: Acetylcysteine; Antibodies, Immobilized; Biosensing Techniques; Cadmium; Electrochemical Techniques; Energy Transfer; Gold; Humans; Immunoassay; Light; Limit of Detection; Metal Nanoparticles; Quantum Dots; Reproducibility of Results; Silver; Tellurium; Troponin I

2017
MAPK/JNK1 activation protects cells against cadmium-induced autophagic cell death via differential regulation of catalase and heme oxygenase-1 in oral cancer cells.
    Toxicology and applied pharmacology, 2017, 10-01, Volume: 332

    Topics: Acetylcysteine; Antioxidants; Autophagy; Cadmium; Caspase 3; Catalase; Cell Line, Tumor; Heme Oxygenase-1; Humans; Mitogen-Activated Protein Kinase 8; Mouth Neoplasms; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Up-Regulation

2017
N-acetylcysteine alleviates cadmium-induced placental endoplasmic reticulum stress and fetal growth restriction in mice.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: Acetylcysteine; Animals; Cadmium; Down-Regulation; Endoplasmic Reticulum Stress; Female; Fetal Growth Retardation; Mice; Placenta; Pregnancy; Real-Time Polymerase Chain Reaction

2018
Binary-ternary Cd(II)-(hydroxycarboxylic acid)-(aromatic chelator) systems exhibit in vitro cytotoxic selectivity in a tissue-specific manner.
    Journal of inorganic biochemistry, 2019, Volume: 195

    Topics: A549 Cells; Acetylcysteine; Adipocytes; Animals; Antioxidants; Apoptosis; Cadmium; Cell Movement; Cell Proliferation; Cell Survival; Chelating Agents; Epithelial Cells; Humans; Hydroxybutyrates; Ligands; Mice; Molecular Structure

2019
Comparative analysis of in vitro neurotoxicity of methylmercury, mercury, cadmium, and hydrogen peroxide on SH-SY5Y cells.
    The Journal of veterinary medical science, 2019, Jun-06, Volume: 81, Issue:6

    Topics: Acetylcysteine; Apoptosis; Cadmium; Cell Line, Tumor; Cell Survival; Heavy Metal Poisoning, Nervous System; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Mercury; Metals, Heavy; Methylmercury Compounds; Oxidative Stress; Reactive Oxygen Species

2019
N-acetylcysteine dual and antagonistic effect on cadmium cytotoxicity in human leukemia cells.
    Environmental toxicology and pharmacology, 2019, Volume: 71

    Topics: Acetylcysteine; Cadmium; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Environmental Pollutants; Humans; K562 Cells; Reactive Oxygen Species; U937 Cells

2019
Cadmium induces cytotoxicity through oxidative stress-mediated apoptosis pathway in duck renal tubular epithelial cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2019, Volume: 61

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cadmium; Cells, Cultured; Ducks; Epithelial Cells; Kidney Tubules; Oxidative Stress

2019
Selenium ameliorates cadmium-induced mouse leydig TM3 cell apoptosis via inhibiting the ROS/JNK /c-jun signaling pathway.
    Ecotoxicology and environmental safety, 2020, Apr-01, Volume: 192

    Topics: Acetylcysteine; Animals; Apoptosis; Cadmium; Cell Line; Cell Survival; JNK Mitogen-Activated Protein Kinases; Leydig Cells; Male; MAP Kinase Signaling System; Mice; Phosphorylation; Reactive Oxygen Species; Selenium; Signal Transduction

2020
The effect of N-acetyl cysteine on oxidative stress and apoptosis in the liver tissue of rats exposed to cadmium.
    Archives of environmental & occupational health, 2021, Volume: 76, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cadmium; Caspase 3; Caspase 8; Gene Expression; Liver; Male; Malondialdehyde; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats

2021
Effects of N-Acetyl Cysteine on Genes Expression of c-myc, and Ask-1, Histopathological, Oxidative Stress, Inflammation, and Apoptosis in the Liver of Male Rats Exposed to Cadmium.
    Biological trace element research, 2022, Volume: 200, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cadmium; Inflammation; Liver; Male; Oxidative Stress; Rats

2022
The effect of N-Acetyl cysteine on the expression of Fxr (Nr1h4), LXRα (Nr1h3) and Sirt1 genes, oxidative stress, and apoptosis in the liver of rats exposed to different doses of cadmium.
    Molecular biology reports, 2021, Volume: 48, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; Cadmium; Gene Expression Regulation; Liver; Liver X Receptors; Male; Oxidative Stress; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Sirtuin 1

2021
N-acetylcysteine restores the cadmium toxicity of Caenorhabditis elegans.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2021, Volume: 34, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Caenorhabditis elegans; Oxidative Stress; Reactive Oxygen Species

2021
Protecting Effects of N-acetyl Cysteine Supplementation Against Lead and Cadmium-Induced Brain Toxicity in Rat Models.
    Biological trace element research, 2022, Volume: 200, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Brain; Cadmium; Dietary Supplements; Lead; Male; Metals, Heavy; Oxidative Stress; Rats

2022
Amelioration of Cadmium-Induced Oxidative Damage in Wistar Rats by Vitamin C, Zinc and
    Medical sciences (Basel, Switzerland), 2022, 01-26, Volume: 10, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cadmium; Oxidative Stress; Rats; Rats, Wistar; Vitamins; Zinc

2022
Transcriptomics-based analysis of co-exposure of cadmium (Cd) and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) indicates mitochondrial dysfunction induces NLRP3 inflammasome and inflammatory cell death in renal tubular epithelial cells.
    Ecotoxicology and environmental safety, 2022, Volume: 241

    Topics: Acetylcysteine; Animals; Cadmium; Caspase 1; Epithelial Cells; Ether; Halogenated Diphenyl Ethers; Humans; Inflammasomes; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Reactive Oxygen Species; Transcriptome

2022
Health risk associated with heavy metal contamination of vegetables grown in agricultural soil of Siran valley, Mansehra, Pakistan-a case study.
    Environmental monitoring and assessment, 2022, Jul-01, Volume: 194, Issue:8

    Topics: Acetylcysteine; Cadmium; Environmental Monitoring; Lead; Metals, Heavy; Pakistan; Soil; Soil Pollutants; Vegetables

2022
Environmental cadmium exposure during gestation impairs fetal brain and cognitive function of adult offspring via reducing placenta-derived E2 level.
    Chemosphere, 2022, Volume: 307, Issue:Pt 1

    Topics: Acetylcysteine; Animals; Brain; Brain-Derived Neurotrophic Factor; Cadmium; Cognition; Estradiol; Estrogens; Female; Male; Mice; Placenta; Pregnancy; Synapsins

2022
[N-acetylcysteine alleviates cadmium-induced testicular interstitial cell apoptosis by activating protein kinase B pathway].
    Wei sheng yan jiu = Journal of hygiene research, 2022, Volume: 51, Issue:4

    Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Cadmium; Leydig Cells; Male; Mice; Oxidative Stress; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species

2022
    Genes, 2022, Sep-27, Volume: 13, Issue:10

    Topics: Acetylcysteine; Apoptosis; Brefeldin A; Cadmium; Fibrosis; Humans; Interleukin-17; Leukocytes, Mononuclear; Mercury; Nicotiana; Oxidative Stress

2022
N-acetylcysteine delayed cadmium-induced chronic kidney injury by activating the sirtuin 1-P53 signaling pathway.
    Chemico-biological interactions, 2023, Jan-05, Volume: 369

    Topics: Acetylcysteine; Animals; Cadmium; Cellular Senescence; Fibrosis; Kidney; Rats; Renal Insufficiency, Chronic; Signal Transduction; Sirtuin 1; Tumor Suppressor Protein p53

2023
Transcriptome analysis reveals insight into the protective effect of N-acetylcysteine against cadmium toxicity in Ganoderma lucidum (Polyporales: Polyporaceae).
    Environmental science and pollution research international, 2023, Volume: 30, Issue:20

    Topics: Acetylcysteine; Animals; Cadmium; Ganoderma; Gene Expression Profiling; Humans; Hydrogen Peroxide; Polyporaceae; Polyporales; Reishi

2023
Pomegranate peel extract, N-Acetylcysteine and their combination with Ornipural alleviate Cadmium-induced toxicity in rats.
    The Journal of veterinary medical science, 2023, Sep-07, Volume: 85, Issue:9

    Topics: Acetylcysteine; Animals; Antioxidants; Cadmium; Plant Extracts; Pomegranate; Rats; Rats, Wistar

2023