acetylcysteine has been researched along with busulfan in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Edwards, K; Jones, AR | 1 |
| Alsadi, S; Edgren, M; Hägglund, H; Hassan, M; Hassan, Z; Hellström-Lindberg, E | 1 |
| Aschan, J; Barkholt, L; Hassan, M; Hassan, Z; Ringdén, O; Sjöö, F | 1 |
| Probin, V; Wang, Y; Zhou, D | 1 |
| Benkessou, F; El-Serafi, A; El-Serafi, I; Hassan, M; Ljungman, P; Martell, E; Mattsson, J; Remberger, M; Zheng, W | 1 |
| Björklund, A; El-Serafi, I; Mattsson, J; Remberger, M; Ringdèn, O; Sundin, M; Törlén, J; Winiarski, J | 1 |
| Cai, C; Han, Y; He, X; Hu, X; Kang, H; Liu, S; Liu, Y; Ma, X; Pan, T; Qi, J; Tang, Y; Wu, D; Yao, Y; Zhang, Z; Zhou, M | 1 |
1 review(s) available for acetylcysteine and busulfan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for acetylcysteine and busulfan
| Article | Year |
|---|---|
Conditioning therapy with N-acetyl-L-cysteine, decitabine and modified BUCY regimen for myeloid malignancies patients prior to allogeneic hematopoietic stem cell transplantation.
Topics: Acetylcysteine; Behavior Therapy; Busulfan; Decitabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Myeloproliferative Disorders; Neoplasms; Prospective Studies; Reactive Oxygen Species; Transplantation Conditioning | 2023 |
11 other study(ies) available for acetylcysteine and busulfan
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Studies with alkylating esters. IV. The metabolism of propane-1,3-dimethanesulphonate and its relevance to the mode of action of Myleran.
Topics: 1-Propanol; Acetylcysteine; Animals; Biotransformation; Busulfan; Carbon Isotopes; Chemosterilants; Chromatography, Paper; Esters; In Vitro Techniques; Male; Methane; Mice; Propylene Glycols; Rabbits; Rats; Spermatozoa; Sulfonic Acids; Sulfur; Sulfur Isotopes; Thiophenes | 1971 |
The effect of modulation of glutathione cellular content on busulphan-induced cytotoxicity on hematopoietic cells in vitro and in vivo.
Topics: Acetylcysteine; Animals; Antigens, CD34; Antineoplastic Agents, Alkylating; Area Under Curve; Bone Marrow Cells; Busulfan; Buthionine Sulfoximine; Cell Death; Colony-Forming Units Assay; Erythroid Precursor Cells; Glutathione; Hematopoietic Stem Cells; Humans; Mice; Mice, Inbred BALB C | 2002 |
N-acetyl-L-cysteine does not affect the pharmacokinetics or myelosuppressive effect of busulfan during conditioning prior to allogeneic stem cell transplantation.
Topics: Acetylcysteine; Adult; Area Under Curve; Bilirubin; Busulfan; Child; Cyclophosphamide; Female; Glutathione; Humans; Immunosuppressive Agents; Infant; Liver; Male; Middle Aged; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome | 2003 |
Busulfan-induced senescence is dependent on ROS production upstream of the MAPK pathway.
Topics: Acetylcysteine; Antineoplastic Agents, Alkylating; beta-Galactosidase; Blotting, Western; Bromodeoxyuridine; Busulfan; Cell Proliferation; Cells, Cultured; Cellular Senescence; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Glutathione; Humans; Lung; Mitogen-Activated Protein Kinases; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2007 |
The effect of N-acetyl-l-cysteine (NAC) on liver toxicity and clinical outcome after hematopoietic stem cell transplantation.
Topics: Acetylcysteine; Antineoplastic Agents, Alkylating; Bilirubin; Busulfan; Hematopoietic Stem Cell Transplantation; Humans; Liver; Liver Function Tests; Transplantation Conditioning; Treatment Outcome | 2018 |
Reduced Risk of Sinusoidal Obstruction Syndrome of the Liver after Busulfan-Cyclophosphamide Conditioning Prior to Allogeneic Hematopoietic Stem Cell Transplantation.
Topics: Acetylcysteine; Adolescent; Adult; Busulfan; Capillaries; Child; Child, Preschool; Cholagogues and Choleretics; Cyclophosphamide; Drug Monitoring; Female; Free Radical Scavengers; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Incidence; Infant; Liver; Male; Middle Aged; Myeloablative Agonists; Retrospective Studies; Risk Assessment; Transplantation Conditioning; Ursodeoxycholic Acid; Young Adult | 2020 |