Compounds > acetylcysteine

acetylcysteine and bupivacaine

acetylcysteine has been researched along with bupivacaine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cho, CH; Jang, BC; Kim, DK; Kim, GH; Lim, JG; Park, GY; Song, DK; Suh, SI; Yoo, SK1
Bourret, A; Capdevila, X; Galbes, O; Matecki, S; Mercier, J; Nouette-Gaulain, K; Philips, A; Pillard, F; Py, G1
Jiang, S; Lai, LY; Li, L; Liu, ZJ; Xu, SY; Zhang, QG; Zhao, W1
Hirota, K; Kusunoki, M; Matsuo, Y; Nishi, K; Okamoto, A; Oku, K; Shingu, K; Sumi, C; Takenaga, K; Tanaka, M1
Ji, Z; Liu, Z; Xia, Z; Xu, H; Xu, R; Xu, S; Zhao, W1

Other Studies

9 other study(ies) available for acetylcysteine and bupivacaine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Muscular cell proliferative and protective effects of N-acetylcysteine by modulating activity of extracellular signal-regulated protein kinase.
    Life sciences, 2006, Jul-10, Volume: 79, Issue:7

    Topics: Acetylcysteine; Anesthetics, Local; Antimetabolites; Antioxidants; Blotting, Western; Bromodeoxyuridine; Bupivacaine; Cell Line; Cell Proliferation; Cell Survival; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Humans; Muscle Cells; Muscle, Skeletal; Myoblasts; Regeneration

2006
N-acetylcysteine protects against bupivacaine-induced myotoxicity caused by oxidative and sarcoplasmic reticulum stress in human skeletal myotubes.
    Anesthesiology, 2010, Volume: 113, Issue:3

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Bupivacaine; Cells, Cultured; Humans; Muscle Fibers, Skeletal; Muscle, Skeletal; Oxidative Stress; Reactive Oxygen Species; Sarcoplasmic Reticulum

2010
OGG1 Involvement in High Glucose-Mediated Enhancement of Bupivacaine-Induced Oxidative DNA Damage in SH-SY5Y Cells.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Bupivacaine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Deoxyguanosine; DNA Damage; DNA Glycosylases; Glucose; Humans; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction

2015
The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells.
    BMC anesthesiology, 2016, 10-24, Volume: 16, Issue:1

    Topics: Acetylcysteine; Anesthetics, Local; Antioxidants; Apoptosis; Bupivacaine; Cell Death; Cell Line, Tumor; Cell Survival; Chromans; Dose-Response Relationship, Drug; HeLa Cells; Humans; Lidocaine; Membrane Potential, Mitochondrial; Mepivacaine; Mitochondria; Neuroblastoma; Reactive Oxygen Species; Time Factors

2016
Mechanistic study of mtROS-JNK-SOD2 signaling in bupivacaine-induced neuron oxidative stress.
    Aging, 2020, 07-13, Volume: 12, Issue:13

    Topics: Acetylcysteine; Animals; Anthracenes; Antioxidants; Bupivacaine; Cell Line, Tumor; Cyclic N-Oxides; Disease Models, Animal; Gene Knockdown Techniques; Humans; Injections, Spinal; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mitochondria; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Rats; Reactive Oxygen Species; RNA, Small Interfering; Superoxide Dismutase; Transcriptional Activation

2020