acetylcysteine and benzo(a)pyrene

acetylcysteine has been researched along with benzo(a)pyrene in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's4 (18.18)18.2507
2000's9 (40.91)29.6817
2010's4 (18.18)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Geeroms, D; Mainguet, P; Roberfroid, M; Wilpart, M1
Balansky, RM; D'Agostini, F; De Flora, S; Izzotti, A; Rossi, GA1
Balansky, R; D'Agostini, F; De Flora, S; Izzotti, A; Scatolini, L1
Bertram, B; Kim, YS; Lee, BH; Lee, S; Wiessler, M1
Griffiths, WJ; Gustafsson, JA; Rafter, J; Sjövall, J; Yang, Y1
Aron, Y; Camilli, T; Hainaut, P; Meplan, C; Polla, BS; Vayssier-Taussat, M; Weksler, B1
Barrett, JC; French, JE; Kari, FW; Martin, KR; Saulnier, M; Trempus, C1
Amin, S; Chiao, JW; Chung, FL; Conaway, CC; Dai, W; Reinhardt, J; Wang, CX; Whysner, J; Yang, YM1
Burchiel, SW; Kepley, CL; Lauer, FT; Oliver, JM1
GUTMANN, HR; WOOD, JL1
Barrett, JC; French, JE; Honeycutt, HP; Jokinen, MP; Kari, FW; Martin, KR; Quinn, A1
Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM1
Balansky, R; Croce, CM; D'Agostini, F; De Flora, S; Di Marco, B; Ganchev, G; Izzotti, A; Lubet, RA; Zanesi, N1
Ibuki, Y; Ohnuki, G; Toyooka, T1
Cho, YH; Choi, JY; Chung, HW; Kang, SJ; Kim, BM; Kim, YJ; Lee, YJ; Woo, HD1
Adams, LD; George, MH; King, LC; Moore, T; Nelson, G; Nesnow, S; Padgett, WT; Ross, JA1
Chiba, T; Furue, M; Gondo, H; Moroi, Y; Tsuji, G; Uchi, H1
He, Q; Montoya-Durango, D; Nanez, A; Ramos, KS; Steffen, MC; Stribinskis, V1
Al-Anati, L; Andersson, PL; Bergman, Å; Högberg, J; Stenius, U; Strid, A; Viluksela, M1
Fu, L; Gao, L; Li, MD; Lv, BB; Tan, ZX; Xiang, HX; Xiang, Y; Xu, DX; Zhang, C; Zhao, H1
Aniagu, S; Chen, T; Huang, Y; Ji, C; Jiang, Y; Tao, Y; Zhang, J1
Arabnezhad, MR; Davani-Davari, D; Ghaffarian-Bahraman, A; Jamshidzadeh, A; Keshavarzi, M; Mohammadi-Bardbori, A1

Other Studies

22 other study(ies) available for acetylcysteine and benzo(a)pyrene

ArticleYear
Desmutagenic effects of N-acetylcysteine on direct and indirect mutagens.
    Mutation research, 1985, Volume: 142, Issue:4

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Anthracenes; Azides; Benzo(a)pyrene; Biotransformation; Dose-Response Relationship, Drug; Fluorenes; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium; Sodium Azide

1985
Pulmonary alveolar macrophages in molecular epidemiology and chemoprevention of cancer.
    Environmental health perspectives, 1993, Volume: 99

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetylcysteine; Adolescent; Adult; Aged; Animals; Benzo(a)pyrene; DNA; DNA Adducts; Female; Humans; Macrophages, Alveolar; Male; Micronuclei, Chromosome-Defective; Middle Aged; Neoplasms; Rats; Rats, Sprague-Dawley; Smoking

1993
Induction by carcinogens and chemoprevention by N-acetylcysteine of adducts to mitochondrial DNA in rat organs.
    Cancer research, 1996, Apr-01, Volume: 56, Issue:7

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; DNA Adducts; DNA Damage; DNA, Mitochondrial; Male; Nicotiana; Plants, Toxic; Rats; Rats, Sprague-Dawley; Smoke

1996
Chemopreventive effects of S-(N,N-diethyldithiocarbamoyl)-N-acetyl-L-cysteine against benzo[a]pyrene.
    Mutation research, 1997, Jul-03, Volume: 377, Issue:2

    Topics: Acetylcysteine; Animals; Antimutagenic Agents; Aroclors; Benzo(a)pyrene; Bone Marrow; Carcinogens; Chlorodiphenyl (54% Chlorine); Chromosome Aberrations; Cricetinae; Dose-Response Relationship, Drug; Fibroblasts; Lung; Male; Mice; Mice, Inbred ICR; Micronucleus Tests; Mutagenicity Tests; Mutagens; Salmonella typhimurium

1997
Analysis of the major mercapturic acid pathway metabolites of benzo[a]pyrene found in rat urine by nano-electrospray mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 1998, Volume: 12, Issue:8

    Topics: Acetylcysteine; Animals; Benzo(a)pyrene; Carcinogens; Chromatography, High Pressure Liquid; Glutathione; Injections, Intraperitoneal; Mass Spectrometry; Molecular Conformation; Rats; Urine

1998
Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3

    Topics: Acetylcysteine; Arteriosclerosis; Benzo(a)pyrene; Cell Death; Cells, Cultured; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Humans; Membrane Potentials; Membrane Proteins; Mitochondria; Monocytes; Oxidative Stress; Reactive Oxygen Species; Smoking

2001
Dietary N-acetyl-L-cysteine modulates benzo[a]pyrene-induced skin tumors in cancer-prone p53 haploinsufficient Tg.AC (v-Ha-ras) mice.
    Carcinogenesis, 2001, Volume: 22, Issue:9

    Topics: Acetylcysteine; Animals; Antioxidants; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Crosses, Genetic; Dietary Supplements; Female; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, ras; Genetic Predisposition to Disease; Haplotypes; Male; Mice; Mice, Transgenic; Skin Neoplasms; Transgenes; Tumor Suppressor Protein p53

2001
Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 a
    Cancer research, 2002, Jan-01, Volume: 62, Issue:1

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Benzo(a)pyrene; Carcinogens; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Isothiocyanates; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transcription Factor AP-1; Tumor Suppressor Protein p53

2002
Environmental polycyclic aromatic hydrocarbons, benzo(a) pyrene (BaP) and BaP-quinones, enhance IgE-mediated histamine release and IL-4 production in human basophils.
    Clinical immunology (Orlando, Fla.), 2003, Volume: 107, Issue:1

    Topics: Acetylcysteine; Air Pollutants; Basophils; Benzo(a)pyrene; Histamine Release; Humans; Immunoglobulin E; Interleukin-4; Oxidants; Quinones; Reactive Oxygen Species; Receptors, IgE; Signal Transduction; Vehicle Emissions

2003
The urinary excretion of mercapturic acids after administration of bromobenzene and 3,4-benzpyrene.
    Cancer research, 1950, Volume: 10, Issue:11

    Topics: Acetylcysteine; Benzo(a)pyrene; Benzopyrenes; Bromobenzenes; Humans; Methionine

1950
Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC).
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 81, Issue:2

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Carcinogens; Diet; Female; Gastric Mucosa; Genes, p53; Genes, ras; Hematologic Neoplasms; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Neoplasms; Papilloma; Pseudolymphoma; Sex Characteristics; Survival Analysis; Urinary Bladder Neoplasms

2004
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
    Cancer research, 2005, Sep-15, Volume: 65, Issue:18

    Topics: Acetylcysteine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weight; Carcinogens; Caspase 3; Caspases; Cell Growth Processes; Disease Progression; Female; In Situ Nick-End Labeling; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Smoking; Sulfoxides; Thiocyanates

2005
Influence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, May-16, Volume: 103, Issue:20

    Topics: Acetylcysteine; Acid Anhydride Hydrolases; Alopecia Areata; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Budesonide; Female; Genes, Tumor Suppressor; Lung; Mice; Mice, Inbred Strains; Neoplasm Proteins; Neoplasms; Stomach

2006
Solar-simulated light-exposed benzo[a]pyrene induces phosphorylation of histone H2AX.
    Mutation research, 2008, Feb-29, Volume: 650, Issue:2

    Topics: Acetylcysteine; Animals; Benzo(a)pyrene; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA Breaks, Double-Stranded; Histones; Phosphorylation; Quinones; Reactive Oxygen Species; Sunlight

2008
Quercetin prevents necrotic cell death induced by co-exposure to benzo(a)pyrene and UVA radiation.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:8

    Topics: Acetylcysteine; Antioxidants; Benzo(a)pyrene; Cell Death; Cell Line, Tumor; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Epithelial Cells; Humans; L-Lactate Dehydrogenase; Necrosis; Quercetin; Reactive Oxygen Species; Sodium Azide; Ultraviolet Rays

2008
Lack of contribution of covalent benzo[a]pyrene-7,8-quinone-DNA adducts in benzo[a]pyrene-induced mouse lung tumorigenesis.
    Chemico-biological interactions, 2010, Jul-30, Volume: 186, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetylcysteine; Animals; Benzo(a)pyrene; Carcinogens; DNA Adducts; Free Radical Scavengers; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred A; Models, Biological; Phosphorus Radioisotopes; Polycyclic Aromatic Hydrocarbons

2010
Arylhydrocarbon receptor (AhR) activation in airway epithelial cells induces MUC5AC via reactive oxygen species (ROS) production.
    Pulmonary pharmacology & therapeutics, 2011, Volume: 24, Issue:1

    Topics: Acetylcysteine; Benzo(a)pyrene; Bronchi; Cells, Cultured; Epithelial Cells; Humans; Mucin 5AC; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; RNA, Messenger

2011
Albumin-like proteins are critical regulators of vascular redox signaling.
    Oxidative medicine and cellular longevity, 2013, Volume: 2013

    Topics: Acetylcysteine; Albumins; Amino Acid Sequence; Animals; Benzo(a)pyrene; Cells, Cultured; Chlorocebus aethiops; COS Cells; Fluorescein-5-isothiocyanate; HEK293 Cells; Hep G2 Cells; Humans; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Muscle, Smooth, Vascular; Oxidation-Reduction; Proteins; Signal Transduction

2013
Hydroxyl metabolite of PCB 180 induces DNA damage signaling and enhances the DNA damaging effect of benzo[a]pyrene.
    Chemico-biological interactions, 2015, Sep-05, Volume: 239

    Topics: Acetylcysteine; Animals; Benzo(a)pyrene; Checkpoint Kinase 1; Cytochrome P-450 CYP1A1; DNA Damage; Drug Synergism; Estradiol; Female; Hep G2 Cells; Histones; Humans; Hydroxyl Radical; Liver; Male; Polychlorinated Biphenyls; Protein Kinases; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction

2015
N-acetylcysteine alleviates pulmonary inflammatory response during benzo[a]pyrene-evoked acute lung injury.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:3

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Benzo(a)pyrene; Lung; Mice; NF-kappa B; Pneumonia

2022
AHR/ROS-mediated mitochondria apoptosis contributes to benzo[a]pyrene-induced heart defects and the protective effects of resveratrol.
    Toxicology, 2021, Volume: 462

    Topics: Acetylcysteine; Animals; Apoptosis; Azo Compounds; Benzo(a)pyrene; Dose-Response Relationship, Drug; Heart Defects, Congenital; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Pyrazoles; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Resveratrol; Zebrafish

2021
Influence of cellular redox environment on aryl hydrocarbon receptor ligands induced melanogenesis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 79

    Topics: Acetylcysteine; Animals; Benzo(a)pyrene; Carbazoles; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Ligands; Melanins; Melanoma; Mice; Onium Compounds; Oxidation-Reduction; Oxidative Stress; Receptors, Aryl Hydrocarbon

2022