acetylcysteine and ascorbic acid

acetylcysteine has been researched along with ascorbic acid in 371 studies

Research

Studies (371)

TimeframeStudies, this research(%)All Research%
pre-199010 (2.70)18.7374
1990's50 (13.48)18.2507
2000's162 (43.67)29.6817
2010's119 (32.08)24.3611
2020's30 (8.09)2.80

Authors

AuthorsStudies
Hara, Y; Inoue, R; Mori, Y; Morii, T; Sato, Y; Shimizu, S; Takahashi, N; Tominaga, M; Yamamoto, S; Yoshida, T1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gonzales, LJ; Parker, CM; Smith, GG; Sprince, H1
Baldewyns, P; Beauduin, M; Gourdin, P; Minette, P; Pluygers, E; Robinet, P1
Breckenridge, AM; Coleman, MD; Hussain, F; Park, BK; Pirmohamed, M1
Hsu, TC; Schantz, SP; Trizna, Z1
Harakeh, S; Jariwalla, RJ2
Han, XL; Liehr, JG1
Bourcier, DR; Kulkarni, AP; Mitra, A; Ravikumar, VC1
Gille, JJ; Joenje, H; Pasman, P; van Berkel, CG1
Arnstein, HR; Cannon, M; Wiseman, H1
Drummer, OH; Henry, PJ; Horowitz, JD1
Chang, R; Marshall, FF; Singh, A1
Cervantes, A; Lankelma, J; Pinedo, HM; Schuurhuis, GJ1
Horstman, MG; Meadows, GG; Yost, GS1
Clavier, RM; Foulks, JG; Jones, K; Perry, TL; Wall, RA; Wright, JM; Yong, VW1
Lieberman, J1
Davis, SS; Dippy, JE1
Forte, AJ; Gillette, JR; Hinson, JA; Mitchell, JR; Nelson, SD; Vaishnav, Y1
Nicolaro, ML; Paterson, CA; Pfister, RR1
Aeschbacher, B; Fluri, M; Meier, B; Rouvinez, G; Schefer, H; Thöni, A; Wagdi, P1
Goepfert, H; Hong, WK; Hsu, TC; Lee, JJ; Schantz, SP; Spitz, MR; Trizna, Z1
Chen, H; Tappel, AL3
Auld, PA; Buist, NR; Jain, A; Kennaway, NG; Mårtensson, J; Powell, BR1
Braakhuis, BJ; Cloos, J; Gille, JJ; Lafleur, MV; Retèl, J; Snow, GB; Steen, I1
Bisby, RH; Johnson, SA; Parker, AW1
McMorris, FA; Vemuri, GS1
Aeschbacher, B; Fikrle, A; Fluri, M; Meier, B; Wagdi, P1
Dimmeler, S; Haendeler, J; Zeiher, AM1
Dimmeler, S; Galle, J; Haendeler, J; Zeiher, AM1
Ponz de Leon, M; Roncucci, L1
Delogu, MR; Desole, MS; Miele, E; Migheli, R; Sciola, L; Sircana, S1
Vile, GF1
Galley, HF; Howdle, PD; Walker, BE; Webster, NR1
Edwards, AD; Hughes, MN; Joashi, U; Kayahara, M; Khan, S; Mazarakis, ND; Mehmet, H; Sarraf, C1
Higuchi, Y; Matsukawa, S1
Chau, YP; Don, MJ; Kuo, ML; Shiah, SG1
Hughes, CM; Lewis, SE; McKelvey-Martin, VJ; Thompson, W1
Chou, CK; Huang, YL; Hwang, KC; Luh, TY; Shen, CK; Yang, HC1
Ozawa, T; Shimazu, Y; Takai, M; Ueda, J1
Cotgreave, IA; Söderholm, K; Voskoboinik, I1
Gräslund, A; Karlberg, AT; Nilsson, JL; Scheynius, A; Van den Broeke, LT; Wahlberg, JE1
Hasegawa, A; Mortola, E; Ohno, K; Okuda, M; Tsujimoto, H; Watari, T1
Dai, J; Jing, Y; Waxman, S; Weinberg, RS1
Azimuddin, K; Ivatury, RR; Porter, JM; Swami, R1
Ahmad, M; Li, WQ; Morin, I; Su, S; Zafarullah, M1
Hamilton, JW; Liu, KJ; Wetterhahn, KE; Yuann, JM1
Cappelletti, G; Maci, R; Maggioni, MG1
De Natale, G; Delogu, MR; Desole, MS; Godani, C; Miele, E; Migheli, R; Sciola, L; Serra, PA; Zangani, D1
Bartsch, H; Hergenhahn, M; Weninger, A; Yang, Q1
Sharma, M; Slocum, HK1
Barnett, YA; Dennog, C; Radermacher, P; Speit, G1
Correa, R; De la Fuente, M; Del Rio, M; Ferrández, MD1
Fujitani, Y; Hanafusa, T; Hori, M; Kajimoto, Y; Kaneto, H; Matsuoka, T; Matsuzawa, Y; Miyagawa, J; Umayahara, Y; Yamasaki, Y1
Mertz, K; Morgan, JI; Schmidt, J1
Csako, G1
Agarwal, R; Shukla, GS1
Hanashima, C; Namiki, H1
Ishikawa, M; Kanno, S; Sasaki, K; Takayanagi, M; Takayanagi, Y1
Hermida-Ameijeiras, A; Labandeira-Garcia, JL; Méndez-Alvarez, E; Muñoz-Patiño, AM; Soto-Otero, R1
Bundy, RE; Chester, AH; Marczin, N; Yacoub, M1
Besséde, G; Gambert, P; Gueldry, S; Lizard, G; Miguet, C; Monier, S; Neel, D1
Davidson, SD; Eshghi, M; Konno, S; Mallouh, C; Nowzari, FB; Tazaki, H1
Delogu, MR; Desole, MS; Enrico, P; Esposito, G; Grella, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, PA1
Diamond, E; Drigues, N; Klein, I; Lischinsky, S; Nagler, R; Reznick, AZ1
Darzynkiewicz, Z; DiPietrantonio, AM; Hsieh, TC; Juan, G; Traganos, F; Wu, JM1
Gohda, E; Iwao, M; Matsunaga, T; Nagao, T; Takebe, T; Wu, YL; Yamamoto, I1
Biesalski, HK; Braun, N; Frank, J; Risler, T1
Aukrust, P; Berge, RK; Frøland, SS; Müller, F; Nordoy, I; Svardal, AM1
Batt, AM; Bertrand, P; Ferrari, L; Gueguen, Y; Malaplate-Armand, C1
Kelly, AM; Thornhill, SM1
Balansky, RM; Camoirano, A; D'Agostini, F; de Flora, S2
Herman, TS; Martinez, BR; Meltz, ML; Mohan, S; Natarajan, M1
Farbiszewski, R; Skrzydlewska, E; Witek, A1
Chung, HY; Han, SI; Kang, HS; Kim, HD; Kim, SH; Oh, SY1
Delogu, MR; Desole, MS; Esposito, G; Miele, E; Miele, M; Migheli, R; Rocchitta, G; Serra, PA2
Benedict, CR; Katagiri, T; Pakala, R; Watanabe, T1
Christopher, MM; Hill, AS; O'Neill, S; Rogers, QR1
Anan, I; Ando, Y; El-Salhy, M; Holmgren, G; Lång, K; Suhr, OB; Tashima, K; Wikström, L1
Kirima, K; Kyaw, M; Tamaki, T; Tsuchiya, K; Yoshizumi, M1
Bershteĭn, LM; Bychkova, NV; Gamaiunova, VB; Kalinina, NM; Kovalenko, IG; Kriuchkova, OG; Poroshina, TE; Tsyrlina, EV; Vasil'ev, DA1
Bahlis, NJ; Boise, LH; Dalton, WS; Grad, JM; Oshiro, MM; Reis, I1
Kern, TS; Kowluru, RA; Tang, J1
Black, S; Lee, J; Medcalf, RL; Sachchithananthan, M; Yu, H1
Ahn, KS; Kim, YS; Lee, J; Moon, KY1
Childs, A; Halliwell, B; Jacobs, C; Kaminski, T; Leeuwenburgh, C1
Bassus, S; Bremerich, D; Busse, R; Görlach, A; Herkert, O; Kirchmaier, CM; Kronemann, N; Schini-Kerth, VB1
Chung, MH; Hong, WS; Jung, HY; Kim, HW; Kim, JH; Lee, HS; Min, YI; Myung, SJ; Yang, SK1
Hermida-Ameijeiras, A; Labandeira-García, JL; López-Martín, ME; Méndez-Alvarez, E; Soto-Otero, R1
De la Fuente, M; Victor, VM1
Antolín, I; Herrera, F; Martín, V; Mayo, JC; Rodriguez, C; Sainz, RM1
Bershtein, LM; Gamayunova, VB; Ivanov, SD; Kalinina, NM; Kovalenko, IG; Poroshina, TE; Solntseva, OS; Tsyrlina, EV; Vasil'ev, DA1
Moyad, MA1
Brown, MK; Fraley, TS; Kaetzel, RS; Reed, DJ; Will, Y1
Häder, DP; He, YY1
Gil, DP; Patiño, P; Rojas, M; Rugeles, MT1
Bruggisser, R; Jundt, G; Schaffner, W; Tullberg-Reinert, H; von Daeniken, K1
Bulger, EM; Garcia, I; Maier, RV1
Roumen, RM; Vader, HL; Van Den Wall Bake, AW; Wijnen, MH1
Hocquette, JF; Muras, P; Orzechowski, A; Łokociejewska, M1
Huang, RF; Huang, SM; Hung, CY; Lin, BS; Lu, HT1
Suntres, ZE1
Baldock, C; De Deene, Y; Healy, BJ; Hurley, C; Mather, M; Venning, A; Vergote, K1
Abe, S; Hasegawa, T; Kirima, K; Kyaw, M; Suzaki, Y; Tamaki, T; Tsuchiya, K; Yoshizumi, M1
Koppolu, P; Kowluru, RA1
Moison, RM; Podda, E; Rijnkels, JM; van Henegouwen, GM1
Karatza, MH; Katsaounou, P; Kollintza, A; Roussos, C; Vassilakopoulos, T; Zakynthinos, S1
Hernanz, A; Martínez, M; Medina, S1
Shyamaladevi, CS; Sridharan, S1
MacNaughton, SM1
Alonso-Lebrero, JL; Brieva, A; Domínguez-Jiménez, C; Pivel, JP; Tejedor, R1
Bershtein, LM; Gamayunova, VB; Kovalenko, IG; Poroshina, TE; Rozanov, YM; Tsyrlina, EV; Vasil'ev, DA1
Bodo, CC; Cabilla, JP; Duvilanski, BH; Poliandri, AH; Velardez, MO1
Chen, K; Feng, H; Wang, X; Zhang, M1
Gripshover, B; McComsey, G; Salata, R; Southwell, H; Valdez, H1
Celik, S; Yilmaz, O1
Hong, SY; Lee, EY; Lee, ZW; Yang, JO1
Fu, J; Zhang, S; Zhou, Z1
Cho, D; Hahm, E; Hur, D; Hwang, YI; Kang, JS; Kim, D; Kim, S; Kim, YI; Kim, YS; Lee, WJ; Pang, S; Park, H; Park, JH; Yang, Y1
Eddleston, JM; Mason, J; McCloy, RF; Schofield, D; Siriwardena, AK; Virlos, IT1
Albers, FW; Busscher, HJ; Elving, GJ; Oosterhof, JJ; Stokroos, I; van der Mei, HC; van Nieuw Amerongen, A; van Weissenbruch, R1
Guerra, MJ; Labandeira-Garcia, JL; Muñoz, AM; Rey, P; Soto-Otero, R1
Bershteĭn, LM; Kovalenko, IG; Poroshina, TE; Tsyrlina, EV; Vasil'ev, DA1
Alpert, E; Altman, H; Barash, V; Barnea, D; Gruzman, A; Sasson, S; Totary, H1
Columbano, A; Cossu, C; Ledda-Columbano, GM; Molotzu, F; Pibiri, M; Sanna, L; Simbula, G1
Dehnade, F; Li, WQ; Liacini, A; Qureshi, HY; Zafarullah, M1
Bastos, ML; Borges, F; Carvalho, F; Carvalho, M; Fernandes, E; Milhazes, N; Remião, F1
Bohosiewicz, J; Byrka-Owczarek, K; Koszutski, T; Krasoń, M; Steplewska-Mazur, K; Wojtynek, G1
Maher, P; Sagara, Y; Vanhnasy, J1
Badrinath, Y; Joshi, DS; Mishra, KP; Narkar, AA; Raghuvar Gopal, DV1
Douglas, P; Kurz, EU; Lees-Miller, SP1
Chen, J; Da, W; Kang, J; Ou, Y1
Kijne, JW; Memelink, J; Pauw, B; van Duijn, B1
Peake, J; Suzuki, K1
Chen, J; Kang, J; Lin, C; Liu, Q; Zhang, D1
Gibran, NS; Muangman, P; Tamura, RN1
Chen, J; Kang, J; Liu, Q; Wanming, D; Zhang, D1
Chang, CC; Lai, CS; Lin, SD; Lin, TM; Tsai, JL1
Gillissen, A; Lukas, R; Schärling, B; Schultze-Werninghaus, G1
Gaspari, AA; Reilly, TP; Roychowdhury, S; Svensson, CK; Vyas, PM1
Airoldi, F; Briguori, C; Colombo, A; Morici, N1
Fatibello-Filho, O; Suarez, WT; Vieira, HJ1
Itoh, Y; Oishi, R; Sendo, T; Yano, T1
Decordier, I; Hantson, P; Haufroid, V; Lison, D; Van Caenegem, O1
Geurtsen, W; Pagoria, D1
Allshire, A; Anoopkumar-Dukie, S; Carey, JB; Conere, T1
Hardman, J; McMahon, R; Redmond, HP; Schofield, D; Shields, C; Siriwardena, AK1
Delles, C; John, S; Oehmer, S; Schmidt, BM; Schmieder, RE; Schneider, MP; Schwarz, TK1
Oudemans-van Straaten, HM1
Liu, XJ; Sun, WM; Tang, XL; Zhao, J; Zheng, RL1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW3
Abate, G; Bordonaro, F; Calvagno, S; Cilio, D; Ignaccolo, L; Leotta, C; Mauceri, B; Neri, S; Pulvirenti, D; Signorelli, SS; Torrisi, B1
Abu-El-Ardat, K; Diab-Assaf, M; Harakeh, S; Khalife, J; Niedzwiecki, A; Rath, M1
Kuo, YM; Wu, Z; Yang, Y; Zhou, B1
Donahue, JJ; Guan, J; Kennedy, AR; Wan, XS; Ware, JH; Zhou, Z1
Ates, B; Batçioğlu, K; Eşrefoğlu, M; Gül, M; Selimoğlu, MA1
Chen, YH; Sun, MF; Wang, JP; Wei, W; Xu, DX1
Shyamaladevi, CS; Vanisree, AJ1
Pannu, N; Tonelli, M1
Briguori, C; Marenzi, G1
Kurebayashi, H; Ohno, Y1
Matkovics, A1
Denton, ML; Eikum, D; Estlack, LE; Foltz, MS; Noojin, GD; Rockwell, BA; Stolarski, DJ; Thomas, RJ1
Ateş, B; Eşrefoğlu, M; Gül, M; Yilmaz, I1
Fu, Q; Hu, BR; Li, JJ; Li, Y; Ming, ZY; Qian, JQ; Tang, Q; Xiang, JZ1
John, SA; Kalimuthu, P; Suresh, D1
Bai, H; Chen, J; Kang, J; Wang, C1
Chi, CS; Fu, YC; Hsu, SL; Hwang, B; Yin, SC1
Columbano, A; Deidda, M; Diana, A; Ledda-Columbano, GM; Pibiri, M; Sanna, L; Simbula, G1
Luchese, C; Nogueira, CW; Rocha, JB; Santos, FW; Zeni, G1
Beshire, M; Dubach, JM; Naik, HB; Soybel, DI; Walsh, BM; Wieland, AM1
Airoldi, F; Bonizzoni, E; Briguori, C; Carlino, M; Colombo, A; Cosgrave, J; D'Andrea, D; Focaccio, A; Michev, I; Montorfano, M; Morici, N; Ricciardelli, B1
Alam, R; Bacsi, A; Boldogh, I; Choudhury, BK; Dharajiya, N; Sur, S1
Bagul, A; Balachandra, S; Formela, L; Galloway, S; Hardman, JG; Jamdar, S; Mason, JM; Siriwardena, AK1
Geurtsen, W; Lee, S; Pagoria, D; Raigrodski, A1
Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S1
Flora, G; Flora, SJ; Mishra, M; Saxena, G1
Alexopoulos, C; Boscos, C; Hadjipavlou-Litina, D; Michael, A; Pontiki, E; Saratsis, P1
Campbell, CT; Kha, V; Kleiner, HE; Landry, GM; Prince, M1
Bhujwalla, ZM; Cheng, L; Dang, CV; Dinavahi, R; Felsher, DW; Gao, P; Lee, LA; Li, F; Pevsner, J; Raman, V; Semenza, GL; Xiang, Y; Zhang, H1
Bhadauria, S; Flora, SJ; Kannan, GM; Singh, N1
Eşrefoğlu, M; Gül, M; Turan, F1
Cacalano, NA; Hume, WR; Jewett, A; Paranjpe, A1
Carmona, A; Martin-Belloso, O; Ramírez, J; Rodríguez, FJ; Rojas-Graü, MA; Tapia, MS1
Cai, Y; Ding, J; Lin, L; Lu, J; Miao, Z1
Chou, SS; Clegg, MS; Hanna, LA; Hong, H; Keen, CL; Momma, TY; Niles, BJ1
Chang, YC; Lin, P1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
McCullough, PA1
Ginsburg, I; Kohen, R; Koren, E; Zverev, I1
Amer, J; Fibach, E; Zelig, O1
Chang, CC; Chang, CH; Kao, AP; Lin, SD; Wang, FY; Wang, KH; Wangchen, H1
Bernstein, SJ; Carlos, RC; Cronin, P; Dwamena, B; Kelly, AM1
Hafer, K; Iwamoto, KS; Schiestl, RH1
Ekor, M; Ezenwadu, TT; Farombi, EO; Oyeyemi, MO; Ugwuezunmba, MC1
Liu, J; Yamashita, U; Yoshida, Y1
Gangapurkar, B; Jariwalla, RJ; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW1
Rudnick, MR; Sterling, KA; Tehrani, T1
Konopka, R; Kubala, L; Lojek, A; Pacherník, J1
Capasso, A; Fiore, G1
Kukner, A; Ozturk, H; Terzi, EH1
Singh, SB; Singh, SN; Singh, VK; Vats, P1
Barchowsky, A; Leikauf, GD; Nemec, AA; Pitt, BR; Wasserloos, KJ1
Kolev, T; Koleva, B; Spiteller, M1
Augusto, AC; Gurgueira, SA; Miguel, F1
Huang, J; Lemire, BD1
Hara, H; Mishima, S; Nakajima, Y; Shimazawa, M; Tsuruma, K1
Chae, IH; Choi, DJ; Choi, YS; Jo, SH; Kang, HJ; Kim, HL; Kim, HS; Kim, YJ; Koo, BK; Oh, BH; Park, JS; Park, YB; Sohn, DW1
Calderon, PB; Verrax, J1
Jariwalla, RJ; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, N1
Kim, D; Kim, DS; Kim, DW; Kim, J; Kim, YJ; Kwon, HJ; Lee, Y; Park, CS; Seo, JN1
Arnold, LL; Cohen, SM; Kakiuchi-Kiyota, S; Pennington, KL; Suzuki, S1
Brown, GC; Brown, RD; Burke, GA1
Meyerstein, D; Meyerstein, N; Rachmilovich-Calis, S1
Lim, HC; Poulose, V; Tan, HH1
Hou, L; Ji, G; Li, N; Li, S; Lu, Y; Ma, S; Peng, D; Qin, M; Shang, L; Xie, K; Xiong, L1
Kalariya, NM; Ramana, KV; Srivastava, SK; van Kuijk, FJ1
Baumeister, P; Harréus, U; Huebner, T; Reiter, M; Schwenk-Zieger, S1
Celik, Y; Cigdem, MK; Kizil, G; Kizil, M; Nergiz, Y; Onen, A1
Han, YH; Moon, HJ; Park, WH; You, BR1
Park, WH; You, BR4
Brown, JR; Mautone, A1
Bracher, A; Doran, SF; Leustik, M; Matalon, S; Postlethwait, EM; Squadrito, GL; Yadav, AK1
Amato, L; Bernardini, G; Braconi, D; Cavallo, G; Laschi, M; Marcolongo, R; Millucci, L; Santucci, A; Spreafico, A1
Bernardini, G; Braconi, D; Cavallo, G; Chellini, F; Galeazzi, M; Gallagher, JA; Marcolongo, R; Millucci, L; Santucci, A; Selvi, E; Spreafico, A; Tinti, L1
Baldwin, EA; Narciso, JA; Plotto, A; Rattanapanone, N1
Alleyne, CH; Dhandapani, KM; Laird, MD; Singh, N; Sukumari-Ramesh, S; Vender, JR1
Green, KN; Hendrix, C; LaFerla, FM; Parachikova, A1
Palani, V; Paramasivan, V; Sathish, P; Sivanesan, K1
Braga, VA; Cardoso, LM; Colombari, E; Giusti, MF; Sato, MA1
Devi, MS; Sudhakaran, PR1
Hekimi, S; Yang, W1
Bruno, RS; Kuiper, HC; Stevens, JF; Traber, MG1
Fibach, E; Freikman, I; Ringel, I1
Aidasani, D; Reid, DL; Skiles, GL; Subramanian, R; Tam, J1
Heo, JS; Lee, JC1
Gao, S; Kim, SH; Oh, YB; Park, WH; Shah, A1
Caruana, M; Giese, A; Hillmer, A; Högen, T; Levin, J; Vassallo, N1
Abe, M; Amou, H; Fujii, S; Harada, T; Hiasa, M; Kagawa, K; Matsumoto, T; Miki, H; Nakamura, S; Nakano, A; Oda, A; Ozaki, S; Takeuchi, K; Watanabe, T1
Bala, A; Haldar, PK; Kar, B; Mazumder, UK; Naskar, S1
Fujita, M; Iwasaka, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K1
Firuzi, O; Miri, R; Saso, L; Tavakkoli, M1
Fan, X; Monnier, VM; Nemet, I; Potts, B; Strauch, CM; Xiaoqin, L1
Coombes, JS; Fassett, RG1
Hsieh, CL; Peng, CC; Peng, RY; Tsai, WJ; Wang, HE1
Gebicki, JM; Liu, CC1
Balansky, R; De Flora, S; Ganchev, G; Iltcheva, M; Steele, VE1
Arai, M; Hikita, E; Hirano, T; Onda, K; Tanaka, S; Toyoda, H; Utsumi, H; Yuan, B1
Blom, H; Frisch, C; Linnebank, M; Semmler, A; Smith, D1
Grahn, H; Kuck, KH; Spangenberg, T; van der Schalk, H1
Cho, BJ; Cho, IJ; Hong, SW; Hwang, JJ; Hwang, YI; Jeong, YJ; Jin, DH; Jung, DJ; Kang, JS; Kim, DE; Kim, DJ; Kim, HS; Kim, JE; Kim, TW; Ko, E; Lee, JS; Lee, SH; Lee, WJ; Moon, JH; Noh, DY; Shin, JS1
Durukan, AB; Durukan, E; Erdem, B; Gurbuz, HA; Gurpinar, A; Karaduman, T; Sevim, H; Yorgancioglu, C1
Armağan, A; Çelik, Ö; Doğan, S; Ergün, O; Nazıroğlu, M; Oksay, T; Özatik, O; Özorak, A1
Baum, O; Hoppeler, H; Meier, P; Renga, M1
Abbasi, H; Aran, S; Ghaffari, A; Keshavarz, A; Seifirad, S; Taslimi, S1
De Capadocia Rosell, J; Jiménez Vizuete, JM; Lozano Serrano, B; Mateo Cerdá, CM1
Alamri, H; Albabtain, MA; Almasood, A; Alshurafah, H; Tamim, H1
Benoit-Vical, F; Berry, A; Gales, A; Huyghe, E; Njomnang Soh, P; Pipy, B; Witkowski, B1
Li, Y; Tang, M; Wang, D; Wang, W; Wu, Q; Ye, B1
Kao, SC; Kau, HC; Lee, FL; Tsai, CC; Wei, YH; Wu, SB1
Amato, L; Bernardini, G; Braconi, D; Chellini, F; Collodel, G; Frediani, B; Geminiani, M; Ghezzi, L; Millucci, L; Moretti, E; Santucci, A; Spreafico, A1
Boedeker, RH; Boening, A; Brueck, M; Cengiz, H; Hoeltgen, R; Scheibelhut, C; Wieczorek, M1
Khan, SR1
Choudhury, M; Eshghi, M; Fishman, AI; Green, D; Konno, S; Lynch, A1
Ge, Y; Gu, N; Guo, D; Huang, Z; Ma, W; Wu, J; Zhang, X; Zhang, Y; Zhao, Y; Zhou, H; Zhou, X; Zhu, L1
Durner, J; Hickel, R; Lottner, S; Reichl, FX; Shehata, M1
Liu, S; Liu, Z; Song, F; Xu, C1
Guo, S; Huang, X; Qi, D; Su, X; Wang, X; Yang, C1
Bian, W; Choi, MM; Fan, M; Guo, W; Li, Y; Lu, D; Ma, J; Shuang, S; Wei, Y1
Hsu, PY; Yang, YW1
Berkelhammer, J; Hopkins, S; Loo, G; Murphy, A; Testa, K1
Barakat, R; Berges, T; Goubet, I; Manon, S; Rosenfeld, E1
Arab, HH; Maghrabi, IA; Omar, HA; Salama, SA; Snapka, RM1
Behnen, M; Hermann, E; Kirchner, T; Klinger, M; Laskay, T; Möller, S; Solbach, W1
May, JM; Meredith, ME; Qu, ZC1
Ferriero, DM; Juul, SE1
Ibrahim, MA; Isah, MB1
Ali-Hassan-Sayegh, S; Dehghan, HR; Kayvanpour, E; Liakopoulos, OJ; Mirhosseini, SJ; Popov, AF; Rezaeisadrabadi, M; Sedaghat-Hamedani, F1
Cingi, C; Dündar, R; İlknur, AE; İnan, S; Katılmış, H; Muluk, NB1
Galli, A; Giannattasio, S; Guaragnella, N; Marra, E; Moro, L1
D'alessandro, A; Gevi, F; Pallotta, V; Zolla, L1
Chan, MH; Chen, HH; Korivi, M; Lee, HJ; Liu, CF; Wu, CY1
Akbulut, S; Dogan, Z; Elbe, H; Erdemli, E; Eris, C; Otan, E; Toprak, G; Turkoz, Y1
Barbosa de Castro, CM; Dornelas de Andrade, AF; Filho, CA; Galvão, AM; Melo-Junior, MR; Silva, LA; Silva, RA; Souza Maia, MB; Streck, EL; Wanderley, MS1
Arroll, MA; Neil, J; Wilder, L1
Agostinelli, S; Arcuri, G; Bielli, A; Costanza, G; Doldo, E; Ferlosio, A; Orlandi, A; Scioli, MG; Tarquini, C1
Ciofu, O; Høiby, N; Jensen, PØ; Johansen, HK; Kræmer, D; Lykkesfeldt, J; Poulsen, HE; Pressler, T; Qvist, T; Skov, M1
Nafar, M; Sahraei, Z; Salamzadeh, J1
Inomata, A; Nakae, D; Nakagawa, Y; Ogata, A1
Chang, HW; Chen, JB; Lee, WC; Li, LC1
Li, CJ; Pang, CY; Sun, LY1
Benkő, Á; György, L; Hegedűs, Z; Hornyák, A; Kőrösi, G; Magyar, H; Szili, K; Vanya, M; Zámolyi, S1
Adem, A; Kalasz, H; Nurulain, SM; Ojha, S; Shafiullah, M; Tekes, K1
Belhomme, M; Buzzacott, P; Guerrero, F; Lambrechts, K; Mazur, A; Theron, M; Wang, Q1
Allen, J; Cosselman, KE; Jansen, KL; Kaufman, JD; Olives, C; Peretz, A; Sack, CS; Stapleton, PL; Trenga, CA1
Amani, A; Fazly Bazzaz, BS; Khameneh, B; Rostami, J; Vahdati-Mashhadian, N1
Habib, M; Hammad, A; Hillis, A1
Aboagye, J; Bass, EB; Choi, MJ; Eng, J; Hutfless, S; Sherrod, C; Suarez-Cuervo, C; Subramaniam, RM; Turban, S; Wilson, RF; Zhang, A1
Andreazza, AC; Berk, M; Dean, O; Kapczinski, F; Magalhães, PV1
Guo, R; Li, H; Wang, Q; Wang, Z; Zhang, D1
Manaf, ZA; Manap, RA; Pirabbasi, E; Rajab, NF; Shahar, S1
Hartwell, J; Hiebert, JB; Pierce, JD; Shen, Q; Thimmesch, AR1
de Sousa Rodrigues, CF; Lira, AB1
Ali- Hasan- Al- Saegh, S; Dehghan, AM; Ghanei, A; Ghodratipour, Z; Haddad, F; Karimi-Bondarabadi, AA; Lotfaliani, M; Mahdavi, P; Mirhosseini, SJ; Popov, AF; Rahimizadeh, E; Sabashnikov, A; Sarrafan-Chaharsoughi, Z; Shahidzadeh, A; Tahernejad, M; Weymann, A; Zeriouh, M1
Gao, Y; He, F; Liu, B; Lu, Z; Sun, X; Wu, Z; Zhang, Y; Zhou, Q1
Chalikias, G; Drosos, I; Tziakas, DN1
Bernard, K; Breton, L; Cacho-Valadez, B; Desjardins, D; Hekimi, S; Khaki, A; Liu, JL; Wang, Y; Yee, C1
Grubeck-Loebenstein, B; Koziel, R; Krismer, M; Lair, J; Meryk, A; Naismith, E; Pangrazzi, L; Trieb, K1
Barfett, J; Jaffer, H; Mikulis, D; Murphy, K; Velauthapillai, N1
Ayyavoo, A; Dandapani, R; Nagasubramanian, V; Raghupathy, P; Rajamani, M1
Bedreag, OH; Cradigati, CA; Dumache, R; Horhat, FG; Luca, L; Papurica, M; Popovici, SE; Rogobete, AF; Sandesc, D; Sarandan, M; Sima, LV; Vernic, C1
Deponte, M; Krafczyk, J; Staudacher, V; Wezena, CA1
Chen, Z; Feng, Y; Huang, X; Li, L1
Heidarian, E; Nikoukar, M; Nouri, A1
de Souza, JA; Horst, A; Kolberg, C; Partata, WA; Riffel, APK; Santos, MCQ1
Garoufalis, G; Makris, D; Palli, E; Papanikolaou, J; Tsilioni, I; Zakynthinos, E; Zygoulis, P1
Bedreag, OH; Bratu, LM; Bratu, T; Cradigati, CA; Dinu, A; Papurica, M; Popovici, SE; Rogobete, AF; Sandesc, D; Sandesc, M; Sarandan, M; Stan, AT1
Du, X; Huang, Z; Liu, W; Ma, K; Peng, M; Shi, P; Sun, J; Wang, Q1
De Magalhaes Filho, CD; Dillin, A; Evans, RM; Henriquez, B; Lapierre, LR; Seah, NE1
Gao, J; Gu, Z; Liang, B; Xu, Y; Zheng, X1
Cui, NX; Jiang, L; Wang, Y; Yi, ZC; Yu, CH; Zhao, X1
Kim, SG; Lee, SH; Seo, SH; Shin, EH; Shin, JH; Yang, JP1
Juránek, I; Rapta, P; Šoltés, L; Valachová, K; Valent, I1
Jacobs, WR; Vilchèze, C1
Andrulewicz-Botulinska, E; Hlebowicz-Sarat, K; Karna, E; Palka, JA; Szoka, L1
Hori, M; Okazaki, Y; Tanaka, H; Toyokuni, S1
Buhling, K; Eulenburg, CZ; Laakmann, E; Schumacher, A1
Chen, HY; Cheng, HT; Lu, JX; Seak, CJ; Smollin, C; Yu, JH1
Li, Z; Long, Y; Luo, G; Shen, W; Shi, X; Zhang, X; Zheng, Z1
Mehrbani Azar, Y; Niesler, CU; van de Vyver, M1
Drummond, PD; Lee-Visser, JLA; Visser, EJ1
Bicheru, NS; Călborean, O; Haidoiu, C; Hertzog, R; Popa, A; Porosnicu, I1
Wu, J1
Cannon, CL; Chen, Q; Chirra, B; DeBerardinis, RJ; Mullen, AR; Shah, KN; Shah, PN; Southerland, MR1
Raftery, MJ; Samstag, Y; Schönrich, G1
Alamdari, AH; Alamdari, DH; Amini, S; Banpour, H; Damsaz, M; Keramati, MR; Koliakos, G; Moghaddam, AB; Yarahmadi, A; Zarmehri, AM1
Accinni, R; Beretta, A; Biswas, P; Dellanoce, C; Malnati, M; Mrakic-Sposta, S; Vezzoli, A1
Ahmad, S; Askari, SN; Gujral, GS; Saluja, K; Zakir, SM1
Brousseau, T; Chevalier-Curt, MJ; Decoin, R; Grzych, G; Henry, H; Maboudou, P; Odou, P; Pekar, JD; Vamecq, J; Vergriete, P1
Benčina, M; Bergant, V; Govednik, T; Grass, V; Hafner-Bratkovič, I; Jazbec, V; Jerala, R; Lainšček, D; Manček-Keber, M; Orehek, S; Pichlmair, A; Plaper, T1
Aguayo, R; Gajardo, A; Lillo-Moya, J; Panieri, E; Prieto, JC; Puentes, Á; Ramos, C; Rodrigo, R; Rojas-Solé, C; Saso, L1
Abd El-Kareem, DM; Almaz, D; El Shehaby, DM; Elsherif, R; Sayed, SA1
Abdelhafez, D; Aboelkomsan, E; Ashur, S; El Sadik, A; Elshimy, A; Lasheen, N; Morcos, GNB1
Ali, T; Arshad, M; Bashir, Z; Fatima, T; Ishtiaq, A; Khan, U; Khan, W; Murtaza, I; Mushtaq, I; Nawaz, M; Sarwar, M; Tabassum, S; Valadi, H1
Alduraywish, AA1
Chen, YT; Hsu, YL; Hung, CH; Liao, WT; Lin, YC; Tsai, MK; Tsai, ML; Tsai, YG1
Aparna, Y; Kandukuri, V; Madduru, R; Motireddy, SR; Poli, V1
Anadón, A; Ares, I; Lopez-Torres, B; Martínez, M; Martinez, MA; Martínez-Larrañaga, MR; Wang, X; Xu, X; Yang, Y1
Dong, Y; Du, GF; Fan, X; Le, YJ; Yang, XY; Yin, A1
Balansky, R; D'Agostini, F; De Flora, S; Garibaldi, S; La Maestra, S; Micale, RT1
Silva, BR; Silva, JRV1
Bergo, MO; Chen, X; Kashif, M; Liu, Y; Schmidt, S; Truong, M; Tüksammel, E; Yao, H1
Ishijima, M; Itoigawa, Y; Koga, A; Maruyama, Y; Morikawa, D; Tsurukami, H; Uehara, H1
Lyublinskaya, O; Tyuryaeva, I1
Geng, Z; Kuerban, B; Luo, G; Wang, Y; Xiao, Y; Xu, Y; Yang, C; Zhao, Z; Zhou, H1
Delgado-Rizo, V; Fafutis-Morris, M; Godínez-Méndez, LA; Muñoz-Sánchez, G1
Bhattacharya, I; Chakraborty, S; Mitra, RK1

Reviews

39 review(s) available for acetylcysteine and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Natural treatment of perennial allergic rhinitis.
    Alternative medicine review : a journal of clinical therapeutic, 2000, Volume: 5, Issue:5

    Topics: Acetylcysteine; Ascorbic Acid; Expectorants; Phytotherapy; Rhinitis, Allergic, Perennial

2000
Results and lessons from clinical trials using dietary supplements for cancer: direct and indirect investigations.
    Seminars in urologic oncology, 2001, Volume: 19, Issue:4

    Topics: Acetylcysteine; Amygdalin; Antioxidants; Ascorbic Acid; beta Carotene; Dietary Supplements; Disease Progression; Humans; Neoplasms; Randomized Controlled Trials as Topic; Selenium; Tissue Extracts; Vitamin A; Vitamin E

2001
Role of antioxidants in paraquat toxicity.
    Toxicology, 2002, Oct-30, Volume: 180, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Glutathione; Herbicides; Humans; Iron Chelating Agents; Liposomes; Melatonin; Metallothionein; NADP; Oxidation-Reduction; Paraquat; Rats; Reactive Oxygen Species; Vitamin E

2002
Neutrophil activation, antioxidant supplements and exercise-induced oxidative stress.
    Exercise immunology review, 2004, Volume: 10

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; DNA Damage; Exercise; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; In Vitro Techniques; Membrane Proteins; Neutrophil Activation; Neutrophils; Oxidative Stress; Reactive Oxygen Species; Vitamin E

2004
New pharmacological protocols to prevent or reduce contrast media nephropathy.
    Minerva cardioangiologica, 2005, Volume: 53, Issue:1

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Contrast Media; Diuretics; Fluid Therapy; Furosemide; Humans; Incidence; Kidney; Mannitol; Renal Insufficiency; Vasoconstriction; Vasodilator Agents

2005
Clinical and experimental evidence for prevention of acute renal failure induced by radiographic contrast media.
    Journal of pharmacological sciences, 2005, Volume: 97, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Adenosine; Alprostadil; Animals; Apoptosis; Ascorbic Acid; Atrial Natriuretic Factor; Contrast Media; Diuretics; Endothelins; Epoprostenol; Fenoldopam; Fluid Therapy; Hemodiafiltration; Hemofiltration; Humans; Iodine Radioisotopes; Kidney Tubules; Models, Biological; Renal Dialysis; Risk Factors

2005
Strategies to prevent contrast nephropathy.
    Minerva cardioangiologica, 2005, Volume: 53, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Ascorbic Acid; Contrast Media; Humans; Phosphodiesterase Inhibitors; Prostaglandins; Theophylline

2005
Strategies to reduce the risk of contrast nephropathy: an evidence-based approach.
    Current opinion in nephrology and hypertension, 2006, Volume: 15, Issue:3

    Topics: Acetylcysteine; Ascorbic Acid; Contrast Media; Evidence-Based Medicine; Fenoldopam; Humans; Kidney Diseases; Osmolar Concentration; Risk Factors; Theophylline

2006
[Recent changes in concepts of antioxidant treatment].
    Orvosi hetilap, 2006, Apr-23, Volume: 147, Issue:16

    Topics: Acetylcysteine; Allopurinol; Antioxidants; Apoptosis; Ascorbic Acid; Cardiovascular Diseases; Clinical Trials as Topic; Coenzymes; Flavonoids; Humans; Meta-Analysis as Topic; Neoplasms; Selenium; Ubiquinone; Vitamin A; Vitamin D; Vitamin E; Vitamin K; Vitamins

2006
Arsenic and lead induced free radical generation and their reversibility following chelation.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, Apr-15, Volume: 53, Issue:1

    Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Calcium; Chelating Agents; Free Radicals; Humans; Lead; Lead Poisoning; Melatonin; Metals; Micronutrients; Molecular Structure; Succimer; Taurine; Thioctic Acid; Unithiol; Vitamin E

2007
Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
    Journal of environmental biology, 2007, Volume: 28, Issue:2 Suppl

    Topics: Acetylcysteine; Animals; Antioxidants; Arsenic Poisoning; Ascorbic Acid; Chelating Agents; Chelation Therapy; Dimercaprol; Drug Therapy, Combination; Environmental Pollutants; Humans; Melatonin; Oxidative Stress; Plant Extracts; Selenium; Succimer; Taurine; Thioctic Acid; Vitamin E; Zinc

2007
Meta-analysis: effectiveness of drugs for preventing contrast-induced nephropathy.
    Annals of internal medicine, 2008, Feb-19, Volume: 148, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Ascorbic Acid; Bicarbonates; Clinical Trials as Topic; Contrast Media; Furosemide; Protective Agents; Research Design; Theophylline

2008
Clinical significance and preventive strategies for contrast-induced nephropathy.
    Current opinion in nephrology and hypertension, 2008, Volume: 17, Issue:6

    Topics: Acetylcysteine; Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Ascorbic Acid; Contrast Media; Fluid Therapy; Hemofiltration; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; Renal Dialysis; Sodium Bicarbonate; Theophylline

2008
Contrast-induced nephropathy in patients undergoing elective and urgent procedures.
    Journal of interventional cardiology, 2010, Volume: 23, Issue:1

    Topics: Acetylcysteine; Acute Disease; Acute Kidney Injury; Adenosine; Ascorbic Acid; Contrast Media; Elective Surgical Procedures; Emergency Treatment; Free Radical Scavengers; General Surgery; Glomerular Filtration Rate; Humans; Hydrotherapy; Preoperative Care; Renal Dialysis; Risk Assessment; Sodium Bicarbonate

2010
Mechanisms and modification of chlorine-induced lung injury in animals.
    Proceedings of the American Thoracic Society, 2010, Volume: 7, Issue:4

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Chlorine; Gases; Inhalation Exposure; Lung; Lung Diseases; Models, Animal; Rabbits; Rats

2010
Antioxidant therapy: current status and future prospects.
    Current medicinal chemistry, 2011, Volume: 18, Issue:25

    Topics: Acetylcysteine; Animals; Antioxidants; Antipyrine; Ascorbic Acid; Edaravone; Humans; Polyphenols; Thioctic Acid; Ubiquinone; Vitamin A; Vitamin E

2011
Antioxidant therapy in hemodialysis patients: a systematic review.
    Kidney international, 2012, Volume: 81, Issue:3

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Oxidative Stress; Renal Dialysis; Vitamin E

2012
[Paraquat poisoning. Case report and overview].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2012, Volume: 107, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Acute Lung Injury; Adult; Antioxidants; Ascorbic Acid; Combined Modality Therapy; Conscious Sedation; Cooperative Behavior; Critical Care; Dose-Response Relationship, Drug; Emergency Medical Services; Esophagoscopy; Esophagus; Gastric Mucosa; Hemofiltration; Herbicides; Humans; Interdisciplinary Communication; Intermittent Positive-Pressure Ventilation; Intestinal Mucosa; Male; Metabolic Clearance Rate; Oxygen Inhalation Therapy; Paraquat; Prognosis; Pulmonary Edema; Suicide, Attempted

2012
Pharmacologic neuroprotective strategies in neonatal brain injury.
    Clinics in perinatology, 2014, Volume: 41, Issue:1

    Topics: Acetylcysteine; Allopurinol; Antioxidants; Ascorbic Acid; Biopterins; Erythropoietin; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Fructose; Humans; Hypoxia-Ischemia, Brain; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Melatonin; Memantine; Neuroprotective Agents; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Topiramate; Vitamin E; Xenon

2014
The role of antioxidants treatment on the pathogenesis of malarial infections: a review.
    Parasitology research, 2014, Volume: 113, Issue:3

    Topics: Acetylcysteine; Antimalarials; Antioxidants; Ascorbic Acid; Deferoxamine; Folic Acid; Humans; Malaria; Oxidative Stress; Plasmodium; Vitamin E

2014
Antioxidant supplementations for prevention of atrial fibrillation after cardiac surgery: an updated comprehensive systematic review and meta-analysis of 23 randomized controlled trials.
    Interactive cardiovascular and thoracic surgery, 2014, Volume: 18, Issue:5

    Topics: Acetylcysteine; Anti-Arrhythmia Agents; Antioxidants; Ascorbic Acid; Atrial Fibrillation; Cardiac Surgical Procedures; Dietary Supplements; Fatty Acids, Unsaturated; Humans; Length of Stay; Odds Ratio; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Treatment Outcome

2014
Nutritional interventions for the adjunctive treatment of schizophrenia: a brief review.
    Nutrition journal, 2014, Sep-16, Volume: 13

    Topics: Acetylcysteine; Antipsychotic Agents; Ascorbic Acid; Databases, Factual; Diet, Gluten-Free; Dietary Supplements; Fatty Acids, Unsaturated; Folic Acid; Glutamates; Humans; Melatonin; Oxidative Stress; Randomized Controlled Trials as Topic; Schizophrenia; Thioctic Acid; Vitamin B Complex; Vitamin D; Vitamin E

2014
Effectiveness of Prevention Strategies for Contrast-Induced Nephropathy: A Systematic Review and Meta-analysis.
    Annals of internal medicine, 2016, Mar-15, Volume: 164, Issue:6

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Contrast Media; Free Radical Scavengers; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney Diseases; Odds Ratio; Sodium Bicarbonate; Sodium Chloride; United States

2016
Antioxidant treatments for schizophrenia.
    The Cochrane database of systematic reviews, 2016, Feb-05, Volume: 2

    Topics: Acetylcysteine; Allopurinol; Antioxidants; Antipsychotic Agents; Ascorbic Acid; Dehydroepiandrosterone; Drug Therapy, Combination; Free Radical Scavengers; Ginkgo biloba; Humans; Oxidative Stress; Randomized Controlled Trials as Topic; Schizophrenia; Selegiline; Vitamin E; Vitamins

2016
Systematic Review of Traumatic Brain Injury and the Impact of Antioxidant Therapy on Clinical Outcomes.
    Worldviews on evidence-based nursing, 2016, Volume: 13, Issue:5

    Topics: Acetylcysteine; Adult; Amino Acids; Antioxidants; Ascorbic Acid; Brain Injuries, Traumatic; Female; Flavonoids; Humans; Male; Progesterone; Quercetin; Treatment Outcome; Vitamin E

2016
Evaluation of oxidative stress markers in obstructive sleep apnea syndrome and additional antioxidant therapy: a review article.
    Sleep & breathing = Schlaf & Atmung, 2016, Volume: 20, Issue:4

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Biomarkers; Continuous Positive Airway Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Lipid Peroxidation; Oxidative Stress; Reactive Oxygen Species; Sleep Apnea, Obstructive

2016
Impact of antioxidant supplementations on cardio-renal protection in cardiac surgery: an updated and comprehensive meta-analysis and systematic review.
    Cardiovascular therapeutics, 2016, Volume: 34, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Antioxidants; Ascorbic Acid; Atrial Fibrillation; Cardiac Surgical Procedures; Dietary Supplements; Fatty Acids, Unsaturated; Humans; Incidence; Odds Ratio; Risk Factors; Treatment Outcome

2016
Prevention of Contrast-Induced Acute Kidney Injury: an Update.
    Cardiovascular drugs and therapy, 2016, Volume: 30, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Aminophylline; Animals; Ascorbic Acid; Contrast Media; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Purinergic P1 Receptor Agonists; Theophylline

2016
N-acetylcysteine versus ascorbic acid or N-acetylcysteine plus ascorbic acid in preventing contrast-induced nephropathy: A meta-analysis.
    Nephrology (Carlton, Vic.), 2018, Volume: 23, Issue:6

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Biomarkers; Chi-Square Distribution; Contrast Media; Creatinine; Drug Therapy, Combination; Humans; Kidney Diseases; Odds Ratio; Protective Factors; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome

2018
Vitamins for Prevention of Contrast-induced Acute Kidney Injury: A Systematic Review and Trial Sequential Analysis.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2018, Volume: 18, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Ascorbic Acid; Contrast Media; Humans; Incidence; Sodium Chloride; Vitamin E

2018
The Isoniazid Paradigm of Killing, Resistance, and Persistence in Mycobacterium tuberculosis.
    Journal of molecular biology, 2019, 08-23, Volume: 431, Issue:18

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Bacterial Proteins; Catalase; Drug Discovery; Drug Resistance, Multiple, Bacterial; Drug Therapy; Gene Transfer, Horizontal; Humans; Isoniazid; Mycobacteriophages; Mycobacterium tuberculosis; Oxidoreductases; Tuberculosis

2019
Influence of oral vitamin and mineral supplementation on male infertility: a meta-analysis and systematic review.
    Reproductive biomedicine online, 2019, Volume: 39, Issue:2

    Topics: Acetylcysteine; Administration, Oral; Ascorbic Acid; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Folic Acid; Humans; Infertility, Male; Male; Minerals; Randomized Controlled Trials as Topic; Selenium; Spermatozoa; Ubiquinone; Vitamin E; Vitamins

2019
Tackle the free radicals damage in COVID-19.
    Nitric oxide : biology and chemistry, 2020, 09-01, Volume: 102

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Azithromycin; Betacoronavirus; Clinical Trials as Topic; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Drug Therapy, Combination; Free Radicals; Glutathione; Humans; Hydroxychloroquine; Mice; Multiple Organ Failure; NF-E2-Related Factor 2; Nitric Oxide; Orthomyxoviridae Infections; Oxidative Stress; Pandemics; Pneumonia, Viral; Reactive Oxygen Species; SARS-CoV-2; Severe Acute Respiratory Syndrome

2020
Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression.
    Advances in biological regulation, 2020, Volume: 77

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Betacoronavirus; Coronavirus Infections; COVID-19; Cytokines; Extracellular Traps; Host-Pathogen Interactions; Humans; Immunity, Innate; Lymphopenia; Neutrophils; NF-kappa B; Oxidative Stress; Pandemics; Pneumonia, Viral; Reactive Oxygen Species; SARS-CoV-2; T-Lymphocytes

2020
Joint Cardioprotective Effect of Vitamin C and Other Antioxidants against Reperfusion Injury in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention.
    Molecules (Basel, Switzerland), 2021, Sep-21, Volume: 26, Issue:18

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Male; Myocardial Infarction; Oxidative Stress; Percutaneous Coronary Intervention; Polyphenols; Protective Agents; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Stroke Volume; Tocopherols; Ventricular Function, Left

2021
Neonicotinoids: mechanisms of systemic toxicity based on oxidative stress-mitochondrial damage.
    Archives of toxicology, 2022, Volume: 96, Issue:6

    Topics: Acetylcysteine; Animals; Antidotes; Antioxidants; Ascorbic Acid; Curcumin; Glutathione; Mammals; Neonicotinoids; Oxidative Stress; Reactive Oxygen Species; Resveratrol

2022
Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development.
    Animal reproduction science, 2023, Volume: 249

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Carnitine; Cysteamine; Embryonic Development; Glutathione; In Vitro Oocyte Maturation Techniques; Lycopene; Melatonin; Oocytes; Oxidative Stress; Phycocyanin; Quercetin; Reactive Oxygen Species; Resveratrol

2023
Expected and Unexpected Effects of Pharmacological Antioxidants.
    International journal of molecular sciences, 2023, May-26, Volume: 24, Issue:11

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Hydrogen Peroxide; Polyphenols

2023

Trials

30 trial(s) available for acetylcysteine and ascorbic acid

ArticleYear
[Cardioprotection in chemo- and radiotherapy for malignant diseases--an echocardiographic pilot study].
    Praxis, 1995, Oct-24, Volume: 84, Issue:43

    Topics: Acetylcysteine; Adult; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Double-Blind Method; Echocardiography; Female; Heart; Heart Ventricles; Humans; Male; Middle Aged; Pilot Projects; Stroke Volume; Vitamin E

1995
Cardioprotection in patients undergoing chemo- and/or radiotherapy for neoplastic disease. A pilot study.
    Japanese heart journal, 1996, Volume: 37, Issue:3

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Double-Blind Method; Heart; Humans; Neoplasms; Pilot Projects; Prospective Studies; Radionuclide Ventriculography; Radiotherapy; Radiotherapy Dosage; Stroke Volume; Vitamin E

1996
Chemoprevention of colorectal tumors: role of lactulose and of other agents.
    Scandinavian journal of gastroenterology. Supplement, 1997, Volume: 222

    Topics: Acetylcysteine; Adenomatous Polyps; Ascorbic Acid; Chemoprevention; Colorectal Neoplasms; Gastrointestinal Agents; Humans; Lactulose; Neoplasm Recurrence, Local; Vitamin A; Vitamin E

1997
The effects of intravenous antioxidants in patients with septic shock.
    Free radical biology & medicine, 1997, Volume: 23, Issue:5

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Drug Therapy, Combination; Free Radicals; Hemodynamics; Humans; Injections, Intravenous; Lipid Peroxides; Male; Middle Aged; Nitrites; Oxidation-Reduction; Shock, Septic; Vitamin E

1997
Antioxidant therapy in the prevention of organ dysfunction syndrome and infectious complications after trauma: early results of a prospective randomized study.
    The American surgeon, 1999, Volume: 65, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Humans; Infections; Injury Severity Score; Multiple Organ Failure; Prospective Studies; Selenium; Treatment Outcome; Vitamin E; Wounds and Injuries

1999
Virological and immunological effects of antioxidant treatment in patients with HIV infection.
    European journal of clinical investigation, 2000, Volume: 30, Issue:10

    Topics: Acetylcysteine; Acquired Immunodeficiency Syndrome; Adult; Antioxidants; Antiviral Agents; Apoptosis; Ascorbic Acid; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Cell Division; Cysteine; Dipeptides; Drug Therapy, Combination; Glutathione; Humans; Interleukin-10; Lipopolysaccharide Receptors; Male; Middle Aged; Monocytes; Neopterin; Oxidative Stress; Pilot Projects; Receptors, Tumor Necrosis Factor; Solubility; Tumor Necrosis Factor-alpha

2000
Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise.
    Free radical biology & medicine, 2001, Sep-15, Volume: 31, Issue:6

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Bleomycin; Creatine Kinase; Dinoprost; Double-Blind Method; Exercise; F2-Isoprostanes; Glutathione Peroxidase; Humans; Interleukin-6; Iron; L-Lactate Dehydrogenase; Lipid Peroxidation; Lipid Peroxides; Male; Muscle, Skeletal; Myoglobin; Myositis; Oxidative Stress; Pain; Peroxidase; Placebos; Superoxide Dismutase

2001
Can renal dysfunction after infra-renal aortic aneurysm repair be modified by multi-antioxidant supplementation?
    The Journal of cardiovascular surgery, 2002, Volume: 43, Issue:4

    Topics: Acetylcysteine; Aged; Albuminuria; Allopurinol; Antioxidants; Aortic Aneurysm, Abdominal; Ascorbic Acid; Female; Humans; Kidney Function Tests; Male; Mannitol; Prospective Studies; Renal Insufficiency; Reperfusion Injury; Vitamin E

2002
Antioxidants attenuate the plasma cytokine response to exercise in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:3

    Topics: Acetylcysteine; Adult; Allopurinol; Antimetabolites; Antioxidants; Ascorbic Acid; Creatine Kinase; Cytokines; Exercise; Flow Cytometry; Free Radical Scavengers; Humans; Interleukin-1; Male; Monocytes; Reactive Oxygen Species; Vitamin A; Vitamin E

2003
Effect of antioxidants on glucose metabolism and plasma lipids in HIV-infected subjects with lipoatrophy.
    Journal of acquired immune deficiency syndromes (1999), 2003, Aug-15, Volume: 33, Issue:5

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Body Composition; Cholesterol; Female; Glucose; HIV-Associated Lipodystrophy Syndrome; Hospitals, University; Humans; Lipids; Male; Middle Aged; Ohio; Pilot Projects; Reverse Transcriptase Inhibitors; Vitamin E

2003
Intravenous n-acetylcysteine, ascorbic acid and selenium-based anti-oxidant therapy in severe acute pancreatitis.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:12

    Topics: Acetylcysteine; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; alpha-Tocopherol; Antioxidants; Ascorbic Acid; beta Carotene; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Oxidative Stress; Pancreatitis; Selenium; Survival Rate

2003
[Antioxidant treatment with N-acetylcysteine and vitamin C in patients with chronic bronchitis].
    Deutsche medizinische Wochenschrift (1946), 2005, Mar-18, Volume: 130, Issue:11

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Blood Sedimentation; Bronchitis, Chronic; Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Glutathione; Humans; Leukocyte Count; Leukocytes, Mononuclear; Luminescent Measurements; Male; Middle Aged; Neutrophils; Reactive Oxygen Species; Spirometry; Surveys and Questionnaires; Treatment Failure

2005
Superoxide scavenging effects of N-acetylcysteine and vitamin C in subjects with essential hypertension.
    American journal of hypertension, 2005, Volume: 18, Issue:8

    Topics: Acetylcholine; Acetylcysteine; Adult; Ascorbic Acid; Blood Flow Velocity; Endothelium, Vascular; Female; Forearm; Free Radical Scavengers; Humans; Hypertension; Infusions, Intra-Arterial; Male; Middle Aged; Nitroprusside; Superoxides; Vasodilation; Vasodilator Agents

2005
Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: a single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controls.
    Clinical therapeutics, 2005, Volume: 27, Issue:11

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Glucose Intolerance; Humans; Male; Oxidants; Oxidative Stress; Postprandial Period; Single-Blind Method; Vitamin E

2005
Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): a randomized comparison of 3 preventive strategies.
    Circulation, 2007, Mar-13, Volume: 115, Issue:10

    Topics: Acetylcysteine; Administration, Oral; Aged; Ascorbic Acid; Cardiovascular Diseases; Contrast Media; Creatinine; Double-Blind Method; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Infusions, Intravenous; Kidney Diseases; Male; Renal Insufficiency; Risk Factors; Sodium Bicarbonate; Sodium Chloride; Treatment Outcome; Triiodobenzoic Acids

2007
Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis.
    Gut, 2007, Volume: 56, Issue:10

    Topics: Acetylcysteine; Acute Disease; Adult; Aged; Antioxidants; APACHE; Ascorbic Acid; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Oxidative Stress; Pancreatitis; Selenium; Treatment Outcome

2007
N-acetylcysteine versus AScorbic acid for preventing contrast-Induced nephropathy in patients with renal insufficiency undergoing coronary angiography NASPI study-a prospective randomized controlled trial.
    American heart journal, 2009, Volume: 157, Issue:3

    Topics: Acetylcysteine; Aged; Antioxidants; Ascorbic Acid; Comorbidity; Contrast Media; Coronary Angiography; Creatinine; Diabetes Mellitus; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Prospective Studies; Renal Insufficiency

2009
Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.
    Free radical biology & medicine, 2011, Apr-01, Volume: 50, Issue:7

    Topics: Acetylcysteine; Administration, Oral; Adolescent; Adult; Aldehydes; Alkenes; Antioxidants; Ascorbic Acid; Biomarkers; Cross-Over Studies; Double-Blind Method; Female; Humans; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidative Stress; Sex Factors; Smoking; Young Adult

2011
Efficacy of ascorbic acid, N-acetylcysteine, or combination of both on top of saline hydration versus saline hydration alone on prevention of contrast-Induced nephropathy: a prospective randomized study.
    Journal of interventional cardiology, 2013, Volume: 26, Issue:1

    Topics: Acetylcysteine; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Contrast Media; Creatinine; Drug Therapy, Combination; Female; Fluid Therapy; Free Radical Scavengers; Humans; Male; Middle Aged; Prospective Studies

2013
Usefulness of N-acetylcysteine or ascorbic acid versus placebo to prevent contrast-induced acute kidney injury in patients undergoing elective cardiac catheterization: a single-center, prospective, randomized, double-blind, placebo-controlled trial.
    The Journal of invasive cardiology, 2013, Volume: 25, Issue:6

    Topics: Acetylcysteine; Acute Kidney Injury; Administration, Intravenous; Aged; Ascorbic Acid; Cardiac Catheterization; Contrast Media; Creatinine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Incidence; Kidney; Male; Prospective Studies; Treatment Outcome; Urea

2013
Storing red blood cells with vitamin C and N-acetylcysteine prevents oxidative stress-related lesions: a metabolomics overview.
    Blood transfusion = Trasfusione del sangue, 2014, Volume: 12, Issue:3

    Topics: Acetylcysteine; Adult; Ascorbic Acid; Blood Preservation; Erythrocytes; Free Radical Scavengers; Humans; Male; Metabolome; Metabolomics; Middle Aged; Oxidative Stress

2014
The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection -- a pilot study.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2015, Volume: 14, Issue:2

    Topics: Acetylcysteine; Administration, Oral; Adult; Antioxidants; Ascorbic Acid; Chronic Disease; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Forced Expiratory Volume; Humans; Inflammation; Lung; Male; Middle Aged; Oxidative Stress; Pseudomonas Infections; Reactive Oxygen Species; Treatment Outcome

2015
Effect of N-acetyl cysteine and vitamin C on kidney allograft function biomarkers interleukin-18 and neutrophil gelatinase-associated lipocalin.
    Iranian journal of kidney diseases, 2015, Volume: 9, Issue:1

    Topics: Acetylcysteine; Acute-Phase Proteins; Adolescent; Adult; Allografts; Antioxidants; Ascorbic Acid; Biomarkers; Delayed Graft Function; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukin-18; Iran; Kidney Transplantation; Lipocalin-2; Lipocalins; Living Donors; Male; Middle Aged; Predictive Value of Tests; Proto-Oncogene Proteins; Time Factors; Treatment Outcome; Young Adult

2015
Pretreatment with Antioxidants Augments the Acute Arterial Vasoconstriction Caused by Diesel Exhaust Inhalation.
    American journal of respiratory and critical care medicine, 2016, 05-01, Volume: 193, Issue:9

    Topics: Acetylcysteine; Adolescent; Adult; Air Pollutants; Antioxidants; Ascorbic Acid; Brachial Artery; Cross-Over Studies; Double-Blind Method; Female; Humans; Inhalation Exposure; Male; Middle Aged; Ultrasonography; Vasoconstriction; Vehicle Emissions; Young Adult

2016
N-acetylcysteine and/or ascorbic acid versus placebo to prevent contrast-induced nephropathy in patients undergoing elective cardiac catheterization: The NAPCIN trial; A single-center, prospective, randomized trial.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2016, Volume: 27, Issue:1

    Topics: Acetylcysteine; Administration, Oral; Aged; Antioxidants; Ascorbic Acid; Cardiac Catheterization; Contrast Media; Coronary Angiography; Creatinine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Kidney Diseases; Male; Middle Aged; Prospective Studies; Treatment Outcome

2016
Efficacy of Ascorbic Acid (Vitamin C) and/N-Acetylcysteine (NAC) Supplementation on Nutritional and Antioxidant Status of Male Chronic Obstructive Pulmonary Disease (COPD) Patients.
    Journal of nutritional science and vitaminology, 2016, Volume: 62, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Antioxidants; Ascorbic Acid; Body Mass Index; Dietary Carbohydrates; Dietary Supplements; Glutathione; Humans; Malaysia; Male; Middle Aged; Nutritional Status; Pulmonary Disease, Chronic Obstructive; Single-Blind Method; Treatment Outcome; Vitamin A

2016
Antioxidants Taken Orally prior to Diagnostic Radiation Exposure Can Prevent DNA Injury.
    Journal of vascular and interventional radiology : JVIR, 2017, Volume: 28, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; beta Carotene; Biomarkers; Bone Neoplasms; DNA Breaks, Double-Stranded; Drug Combinations; Histones; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasm Staging; Ontario; Oxidative Stress; Predictive Value of Tests; Prospective Studies; Radiation Injuries; Radiopharmaceuticals; Technetium Tc 99m Medronate; Thioctic Acid; Time Factors; Treatment Outcome

2017
The impact of N-acetylcysteine and ascorbic acid in contrast-induced nephropathy in critical care patients: an open-label randomized controlled study.
    Critical care (London, England), 2017, Oct-31, Volume: 21, Issue:1

    Topics: Acetylcysteine; Acute Kidney Injury; Administration, Intravenous; Ascorbic Acid; Blood Urea Nitrogen; Contrast Media; Creatinine; Critical Care; Female; Greece; Humans; Intensive Care Units; Kidney; Male; Middle Aged; Multivariate Analysis; Prospective Studies; ROC Curve; Statistics, Nonparametric; Tomography, X-Ray Computed

2017
Reduction in Migraine and Headache Frequency and Intensity With Combined Antioxidant Prophylaxis (N-acetylcysteine, Vitamin E, and Vitamin C): A Randomized Sham-Controlled Pilot Study.
    Pain practice : the official journal of World Institute of Pain, 2020, Volume: 20, Issue:7

    Topics: Acetylcysteine; Adult; Aged; Antioxidants; Ascorbic Acid; Australia; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Migraine Disorders; Pilot Projects; Treatment Outcome; Vitamin E

2020
Antioxidant Activity with Increased Endogenous Levels of Vitamin C, E and A Following Dietary Supplementation with a Combination of Glutathione and Resveratrol Precursors.
    Nutrients, 2020, Oct-22, Volume: 12, Issue:11

    Topics: Acetylcysteine; Aged; Alanine; Antioxidants; Ascorbic Acid; Dietary Supplements; Erythrocytes; Female; Glucosides; Glutamine; Glutathione; Glycine; Humans; Ketoglutaric Acids; Male; Middle Aged; Neopterin; Oxidation-Reduction; Resveratrol; Stilbenes; Sulfhydryl Compounds; Vitamin A; Vitamin E; Vitamins

2020

Other Studies

302 other study(ies) available for acetylcysteine and ascorbic acid

ArticleYear
Nitric oxide activates TRP channels by cysteine S-nitrosylation.
    Nature chemical biology, 2006, Volume: 2, Issue:11

    Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Chickens; Cysteine; Humans; Models, Molecular; Molecular Structure; Nitric Oxide; Nitrogen Compounds; Protein Binding; Sensitivity and Specificity; Signal Transduction; Sulfhydryl Compounds; Time Factors; Transient Receptor Potential Channels

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking.
    Agents and actions, 1975, Volume: 5, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Alcoholism; Anesthetics; Animals; Ascorbic Acid; Cysteine; Humans; Lethal Dose 50; Male; Rats; Smoking; Sulfur; Thiamine

1975
Biomarker assessments in asbestos-exposed workers as indicators for selective prevention of mesothelioma or bronchogenic carcinoma: rationale and practical implementations.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1992, Volume: 1, Issue:2

    Topics: Acetylcysteine; Antigens, Neoplasm; Asbestos; Ascorbic Acid; beta Carotene; Biomarkers, Tumor; Carcinoembryonic Antigen; Carcinoma, Bronchogenic; Carotenoids; Cohort Studies; Ferritins; Humans; Hyaluronic Acid; Longitudinal Studies; Lung Neoplasms; Male; Mesothelioma; Middle Aged; Occupational Diseases; Occupational Exposure; Peptides; Riboflavin; Selenium; Tissue Polypeptide Antigen; Vitamin A; Vitamin E

1992
Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:3

    Topics: Acetylcysteine; Ascorbic Acid; Biotransformation; Cell Survival; Chromatography, High Pressure Liquid; Erythrocytes; Glutathione; Humans; Ketoconazole; Leukocytes, Mononuclear; Methemoglobin; Microsomes, Liver; Sulfasalazine

1991
Effects of N-acetyl-L-cysteine and ascorbic acid on mutagen-induced chromosomal sensitivity in patients with head and neck cancers.
    American journal of surgery, 1991, Volume: 162, Issue:4

    Topics: Acetylcysteine; Ascorbic Acid; Bleomycin; Cell Line; Chromosome Fragility; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Head and Neck Neoplasms; Humans; In Vitro Techniques; Lymphocytes; Tumor Cells, Cultured

1991
Comparative study of the anti-HIV activities of ascorbate and thiol-containing reducing agents in chronically HIV-infected cells.
    The American journal of clinical nutrition, 1991, Volume: 54, Issue:6 Suppl

    Topics: Acetylcysteine; Ascorbic Acid; Cell Division; Cells, Cultured; Glutathione; HIV; Humans; RNA-Directed DNA Polymerase; Sulfhydryl Compounds

1991
Induction of covalent DNA adducts in rodents by tamoxifen.
    Cancer research, 1992, Mar-01, Volume: 52, Issue:5

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Cricetinae; DNA; Female; Kidney; Liver; Premedication; Rats; Rats, Inbred Strains; Tamoxifen

1992
Effect of ascorbic acid esters on hepatic glutathione levels in mice treated with a hepatotoxic dose of acetaminophen.
    Journal of biochemical toxicology, 1991,Summer, Volume: 6, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Ascorbic Acid; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Isocitrate Dehydrogenase; Liver; Male; Mice; Sulfobromophthalein

1991
Effect of antioxidants on hyperoxia-induced chromosomal breakage in Chinese hamster ovary cells: protection by carnosine.
    Mutagenesis, 1991, Volume: 6, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Carnosine; Cell Line; Chromosome Aberrations; Ethoxyquin; G2 Phase; Glutathione; Histamine; Imidazoles; Oxygen; Vitamin E

1991
Protection by glutathione against one component of the bimodal inhibition of growth by tamoxifen in Saccharomyces cerevisiae.
    Biochemical Society transactions, 1990, Volume: 18, Issue:4

    Topics: Acetylcysteine; Ascorbic Acid; Breast Neoplasms; Cell Division; Glutathione; Humans; Saccharomyces cerevisiae; Tamoxifen; Tumor Cells, Cultured

1990
S-nitrosothiols as vasodilators: implications regarding tolerance to nitric oxide-containing vasodilators.
    British journal of pharmacology, 1989, Volume: 98, Issue:3

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Cattle; Chromatography, High Pressure Liquid; Coronary Vessels; Cystine; Drug Tolerance; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1989
Cystine calculi: clinical management and in vitro observations.
    Urology, 1988, Volume: 31, Issue:3

    Topics: Acetylcysteine; Adult; Ascorbic Acid; Bicarbonates; Cystine; Cystinuria; Female; Homozygote; Humans; Kidney Calculi; Male; Middle Aged; Penicillamine; Sodium; Sodium Bicarbonate; Tromethamine

1988
The role of oxygen-derived free radicals in the cytotoxicity of doxorubicin in multidrug resistant and sensitive human ovarian cancer cells.
    Cancer letters, 1988, Aug-15, Volume: 41, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Benzoates; Benzoic Acid; Catalase; Cell Division; Cell Survival; Doxorubicin; Drug Resistance; Female; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Kinetics; Mannitol; Ovarian Neoplasms; Oxygen; Superoxide Dismutase; Tumor Cells, Cultured

1988
Separate mechanisms for procarbazine spermatotoxicity and anticancer activity.
    Cancer research, 1987, Mar-15, Volume: 47, Issue:6

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Dose-Response Relationship, Drug; Glutathione; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Procarbazine; Spermatozoa

1987
Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse.
    Neuroscience letters, 1985, Sep-30, Volume: 60, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Carotenoids; Corpus Striatum; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Pyridines; Substantia Nigra; Vitamin E

1985
The appropriate use of mucolytic agents.
    The American journal of medicine, 1970, Volume: 49, Issue:1

    Topics: Acetylcysteine; Anti-Bacterial Agents; Ascorbic Acid; Bronchi; Bronchitis; Bronchodilator Agents; Deoxyribonucleases; DNA; Edetic Acid; Epithelium; Glycosaminoglycans; Humans; Mucus; Peptide Hydrolases; Respiratory Therapy; Sputum; Trachea; Urea; Viscosity

1970
Rheological assessment of mucolytic agents on sputum of chronic bronchitics.
    Thorax, 1969, Volume: 24, Issue:6

    Topics: Acetylcysteine; Ascorbic Acid; Bronchitis; Copper; Expectorants; Humans; Hydrogen Peroxide; Rheology; Sputum; Viscosity

1969
The formation of arylating and alkylating metabolites of phenacetin in hamsters and hamster liver microsomes.
    Molecular pharmacology, 1981, Volume: 19, Issue:1

    Topics: Acetylcysteine; Alkylation; Animals; Ascorbic Acid; Biotransformation; Carbon Dioxide; Cricetinae; Cysteine; Glutathione; In Vitro Techniques; Microsomes, Liver; Phenacetin; Protein Binding

1981
Sodium citrate reduces the incidence of corneal ulcerations and perforations in extreme alkali-burned eyes--acetylcysteine and ascorbate have no favorable effect.
    Investigative ophthalmology & visual science, 1981, Volume: 21, Issue:3

    Topics: Acetylcysteine; Administration, Topical; Alkalies; Animals; Ascorbic Acid; Burns, Chemical; Citrates; Citric Acid; Corneal Ulcer; Eye Burns; Rabbits

1981
In vitro protective effects of chemopreventive agents against bleomycin-induced genotoxicity in lymphoblastoid cell lines and peripheral blood lymphocytes of head and neck cancer patients.
    Cancer detection and prevention, 1993, Volume: 17, Issue:6

    Topics: Acetylcysteine; Anticarcinogenic Agents; Antimutagenic Agents; Ascorbic Acid; Bleomycin; Cell Line; Chromosome Aberrations; Head and Neck Neoplasms; Humans; Lymphocytes; Tretinoin; Vitamin E

1993
Vitamin E, selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q, beta-carotene, canthaxanthin, and (+)-catechin protect against oxidative damage to kidney, heart, lung and spleen.
    Free radical research, 1995, Volume: 22, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Canthaxanthin; Carotenoids; Catechin; Chromans; Heart; Liver; Lung; Male; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Selenium; Spleen; Ubiquinone; Vitamin E

1995
Protection of vitamin E, selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q0, coenzyme Q10, beta-carotene, canthaxanthin, and (+)-catechin against oxidative damage to rat blood and tissues in vivo.
    Free radical biology & medicine, 1995, Volume: 18, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Canthaxanthin; Carotenoids; Catechin; Chromans; Coenzymes; Heart; Hemeproteins; Kidney; Liver; Lung; Male; Myocardium; Oxidation-Reduction; Oxidative Stress; Palmitic Acid; Palmitic Acids; Rats; Rats, Sprague-Dawley; Selenium; Spleen; Ubiquinone; Vitamin E; Vitamin E Deficiency

1995
Protection by vitamin E selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q, beta-carotene, canthaxanthin, and (+)-catechin against oxidative damage to liver slices measured by oxidized heme proteins.
    Free radical biology & medicine, 1994, Volume: 16, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Canthaxanthin; Carotenoids; Catechin; Chromans; Dose-Response Relationship, Drug; Hemeproteins; In Vitro Techniques; Male; Oxidants; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Selenium; Ubiquinone; Vitamin D Deficiency; Vitamin E

1994
Effect of ascorbate or N-acetylcysteine treatment in a patient with hereditary glutathione synthetase deficiency.
    The Journal of pediatrics, 1994, Volume: 124, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Child, Preschool; Female; Glutathione Synthase; Humans; Lymphocytes; Metabolism, Inborn Errors; Vitamin E

1994
Influence of the antioxidant N-acetylcysteine and its metabolites on damage induced by bleomycin in PM2 bacteriophage DNA.
    Carcinogenesis, 1996, Volume: 17, Issue:2

    Topics: Acetylcysteine; Antibiotics, Antineoplastic; Ascorbic Acid; Bacteriophages; Bleomycin; DNA; DNA Damage; DNA, Single-Stranded; DNA, Superhelical; DNA, Viral; Drug Synergism; Free Radical Scavengers; Glutathione

1996
Quenching of reactive oxidative species by probucol and comparison with other antioxidants.
    Free radical biology & medicine, 1996, Volume: 20, Issue:3

    Topics: Acetylcysteine; Antimutagenic Agents; Antioxidants; Ascorbic Acid; Benzophenones; Benzoquinones; Free Radicals; Oxidation-Reduction; Photolysis; Probucol; Reactive Oxygen Species; Spectrophotometry; Spectrum Analysis, Raman; Thioctic Acid; Vitamin E

1996
Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival.
    Development (Cambridge, England), 1996, Volume: 122, Issue:8

    Topics: Acetylcysteine; Androstadienes; Apoptosis; Ascorbic Acid; Blood; Cell Survival; Chromones; Ciliary Neurotrophic Factor; Enzyme Inhibitors; Fibroblast Growth Factor 2; Insulin-Like Growth Factor I; Morpholines; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Oligodendroglia; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Signal Transduction; Stem Cells; Vitamin E; Wortmannin

1996
Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax.
    European journal of pharmacology, 1996, Dec-19, Volume: 317, Issue:2-3

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; bcl-2-Associated X Protein; Blotting, Northern; Blotting, Western; Cells, Cultured; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Female; Humans; Lipopolysaccharides; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Umbilical Veins; Vitamin E

1996
Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis.
    Circulation, 1997, Apr-01, Volume: 95, Issue:7

    Topics: Acetylcysteine; Apoptosis; Ascorbic Acid; Caspase 3; Caspases; Cells, Cultured; Cysteine Endopeptidases; DNA Fragmentation; Endopeptidases; Endothelium, Vascular; Enzyme Activation; Humans; Lipoproteins, LDL; Vitamin E

1997
NF-kappa B-independent suppression of HIV expression by ascorbic acid.
    AIDS research and human retroviruses, 1997, Feb-10, Volume: 13, Issue:3

    Topics: Acetylcysteine; Ascorbic Acid; Cell Line; HIV; Humans; Hydrogen Peroxide; NF-kappa B; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha; Virus Latency; Virus Replication

1997
Role of oxidative stress in the manganese and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced apoptosis in PC12 cells.
    Neurochemistry international, 1997, Volume: 31, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Survival; Manganese; Oxidative Stress; PC12 Cells; Rats

1997
Active oxygen species mediate the solar ultraviolet radiation-dependent increase in the tumour suppressor protein p53 in human skin fibroblasts.
    FEBS letters, 1997, Jul-21, Volume: 412, Issue:1

    Topics: Acetylcysteine; Ascorbic Acid; Cells, Cultured; DNA Damage; Fibroblasts; Free Radical Scavengers; Humans; Hydrogen Peroxide; Kinetics; Reactive Oxygen Species; Skin; Sunlight; Tumor Suppressor Protein p53; Ultraviolet Rays; Vitamin E

1997
Differential induction of apoptosis in Swiss 3T3 cells by nitric oxide and the nitrosonium cation.
    Journal of cell science, 1997, Volume: 110 ( Pt 18)

    Topics: 3T3 Cells; Acetylcysteine; Animals; Antidotes; Antioxidants; Apoptosis; Ascorbic Acid; Carrier Proteins; Cations; DNA Fragmentation; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Hydrogen-Ion Concentration; Membrane Proteins; Mice; Microscopy, Electron; Microscopy, Fluorescence; Mitochondria; Nitric Oxide; Nitroso Compounds; Oxyhemoglobins; Platelet Aggregation Inhibitors; Poly(ADP-ribose) Polymerases; S-Nitrosoglutathione; Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins; Time Factors; Vesicular Transport Proteins

1997
Active oxygen-mediated chromosomal 1-2 Mbp giant DNA fragmentation into internucleosomal DNA fragmentation in apoptosis of glioma cells induced by glutamate.
    Free radical biology & medicine, 1998, Volume: 24, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Catalase; Chromosomes; Deferoxamine; DNA Fragmentation; Free Radical Scavengers; Glioma; Glutamic Acid; Glutathione; Hydrogen Peroxide; Iron Chelating Agents; Oxidation-Reduction; Oxygen; Phenanthrolines; Rats; Tumor Cells, Cultured

1998
Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells.
    Free radical biology & medicine, 1998, Mar-01, Volume: 24, Issue:4

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cell Differentiation; DNA Fragmentation; Drug Resistance; Enzyme Inhibitors; Glutathione; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; Monocytes; Naphthoquinones; Proto-Oncogene Proteins c-bcl-2; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Vitamin E

1998
The effects of antioxidant supplementation during Percoll preparation on human sperm DNA integrity.
    Human reproduction (Oxford, England), 1998, Volume: 13, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Separation; DNA; DNA Damage; Humans; In Vitro Techniques; Infertility, Male; Male; Povidone; Reactive Oxygen Species; Reproductive Techniques; Silicon Dioxide; Spermatozoa; Uric Acid; Vitamin E

1998
Blockage of apoptotic signaling of transforming growth factor-beta in human hepatoma cells by carboxyfullerene.
    European journal of biochemistry, 1998, May-15, Volume: 254, Issue:1

    Topics: Acetylcysteine; Apoptosis; Ascorbic Acid; Carbon; Carboxylic Acids; Carcinoma, Hepatocellular; Cell Survival; Flow Cytometry; Fluorescent Dyes; Free Radical Scavengers; Fullerenes; Humans; Liposomes; Molecular Structure; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Reactive Oxygen Species; Signal Transduction; Stereoisomerism; Transforming Growth Factor beta; Tumor Cells, Cultured

1998
Reactive oxygen species generated from the reaction of copper(II) complexes with biological reductants cause DNA strand scission.
    Archives of biochemistry and biophysics, 1998, Sep-15, Volume: 357, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Copper; DNA Damage; Electron Spin Resonance Spectroscopy; Glutathione; Hydrogen Peroxide; Hydroquinones; Hydroxyl Radical; Oxidation-Reduction; Plasmids; Reactive Oxygen Species; Reducing Agents; Spin Trapping

1998
Ascorbate and glutathione homeostasis in vascular smooth muscle cells: cooperation with endothelial cells.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Acetylcysteine; Ascorbic Acid; Cells, Cultured; Coculture Techniques; Cystine; Dehydroascorbic Acid; Endothelium, Vascular; Glutathione; Homeostasis; Humans; Kinetics; Methionine; Muscle, Smooth, Vascular; Oxidation-Reduction; Phloretin; Umbilical Veins

1998
Free radicals as potential mediators of metal-allergy: Ni2+- and Co2+-mediated free radical generation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1998, Volume: 6, Issue:4

    Topics: Acetylcysteine; Adult; Ascorbic Acid; Carnosine; Cells, Cultured; Cobalt; Cysteine; Dermatitis, Allergic Contact; Electron Spin Resonance Spectroscopy; Female; Free Radical Scavengers; Free Radicals; Glutathione; Histidine; Humans; Hydrogen Peroxide; Middle Aged; Monocytes; Nickel

1998
Inhibition of apoptosis and virus replication in feline immunodeficiency virus-infected cells by N-acetylcysteine and ascorbic acid.
    The Journal of veterinary medical science, 1998, Volume: 60, Issue:11

    Topics: Acetylcysteine; Animals; Apoptosis; Ascorbic Acid; Cats; Cell Line; DNA Fragmentation; DNA, Viral; Fibroblasts; Free Radical Scavengers; Humans; Immunodeficiency Virus, Feline; Lentivirus Infections; Recombinant Proteins; T-Lymphocytes; Virus Replication

1998
Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system.
    Blood, 1999, Jan-01, Volume: 93, Issue:1

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cells, Cultured; Drug Synergism; Glutathione; Growth Inhibitors; Hematopoietic Stem Cells; HL-60 Cells; Humans; Lymphoma; Mice; Mice, Inbred Strains; Oxidation-Reduction; Oxides; Tumor Cells, Cultured

1999
Induction of stromelysin gene expression by tumor necrosis factor alpha is inhibited by dexamethasone, salicylate, and N-acetylcysteine in synovial fibroblasts.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cattle; Cells, Cultured; Dexamethasone; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Ibuprofen; Indomethacin; Matrix Metalloproteinase 3; Proline; Sodium Salicylate; Synovial Membrane; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vitamin E

1999
In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium-DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of osteogenic disorder shionogi rats following treatment with chromium(VI).
    Carcinogenesis, 1999, Volume: 20, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antimetabolites; Ascorbic Acid; Buthionine Sulfoximine; Chromium; Deoxyguanosine; DNA Adducts; Free Radical Scavengers; Glutathione; Ketones; Kidney; Liver; Oxidation-Reduction; Rats; Rats, Mutant Strains

1999
Apoptosis in human lung epithelial cells: triggering by paraquat and modulation by antioxidants.
    Cell biology international, 1998, Volume: 22, Issue:9-10

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cell Line; Epithelial Cells; Humans; Lung; Models, Biological; Paraquat; Reactive Oxygen Species

1998
Enhancing effect of manganese on L-DOPA-induced apoptosis in PC12 cells: role of oxidative stress.
    Journal of neurochemistry, 1999, Volume: 73, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Survival; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Drug Synergism; Flow Cytometry; Levodopa; Manganese Poisoning; Oxidative Stress; PC12 Cells; Rats

1999
Cigarette smoke induces direct DNA damage in the human B-lymphoid cell line Raji.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Acetaldehyde; Acetylcysteine; Acrolein; Aldehydes; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; B-Lymphocytes; beta-Naphthoflavone; Biotransformation; Burkitt Lymphoma; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Neoplasm; Formaldehyde; Free Radical Scavengers; Gamma Rays; Humans; Mixed Function Oxygenases; N-Glycosyl Hydrolases; Oxidation-Reduction; Reactive Oxygen Species; Smoke

1999
Prevention of quinone-mediated DNA arylation by antioxidants.
    Biochemical and biophysical research communications, 1999, Sep-07, Volume: 262, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Diethylstilbestrol; DNA Adducts; Horseradish Peroxidase; Hydrogen Peroxide; Male; Salmon; Tamoxifen; Testis

1999
Antioxidant status in humans after exposure to hyperbaric oxygen.
    Mutation research, 1999, Jul-16, Volume: 428, Issue:1-2

    Topics: Acetylcysteine; Adaptation, Physiological; Adult; Antioxidants; Ascorbic Acid; DNA Damage; Erythrocytes; Glutathione; Humans; Hydrogen Peroxide; Hyperbaric Oxygenation; In Vitro Techniques; Leukocytes; Lymphocytes; Vitamin A; Vitamin E

1999
Effects in vitro of several antioxidants on the natural killer function of aging mice.
    Experimental gerontology, 1999, Volume: 34, Issue:5

    Topics: Acetylcysteine; Aging; Animals; Antioxidants; Ascorbic Acid; Killer Cells, Natural; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Peritoneum; Spleen; Thiazoles; Thiazolidines; Thymus Gland; Vitamin E

1999
Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity.
    Diabetes, 1999, Volume: 48, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Insulin Resistance; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Vitamin E

1999
Regulation of heme oxygenase-1 expression by dopamine in cultured C6 glioma and primary astrocytes.
    Brain research. Molecular brain research, 1999, Nov-10, Volume: 73, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Astrocytes; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Line; Cycloheximide; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glioma; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Membrane Proteins; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; RNA, Messenger; Selegiline; Time Factors; Tumor Cells, Cultured

1999
Mesna and other free-sulfhydryl compounds produce false-positive results in a urine test strip method for ascorbic acid.
    Clinical chemistry, 1999, Volume: 45, Issue:12

    Topics: Acetylcysteine; Ascorbic Acid; Captopril; False Positive Reactions; Humans; Mesna; Reagent Strips

1999
Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.
    Neurochemical research, 1999, Volume: 24, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Brain; Curcuma; Glutathione; Ketones; Liver; Male; Maleates; Plant Extracts; Rats; Rats, Inbred Strains; Vitamin E

1999
Reduced viability of vascular endothelial cells by high concentration of ascorbic acid in vitreous humor.
    Cell biology international, 1999, Volume: 23, Issue:4

    Topics: Acetylcysteine; Animals; Aorta; Ascorbic Acid; Catalase; Cattle; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Vitreous Body

1999
Characterization of hydrogen peroxide-induced apoptosis in mouse primary cultured hepatocytes.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Hydrogen Peroxide; Liver; Male; Mice

2000
Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cysteine; Female; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Neurons; Oxidation-Reduction; Oxidopamine; Oxygen Consumption; Parkinson Disease; Rats; Rats, Sprague-Dawley; Sympatholytics

2000
A redox-based mechanism for nitric oxide-induced inhibition of DNA synthesis in human vascular smooth muscle cells.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Free Radical Scavengers; G1 Phase; Glutathione; Humans; Hydroxyurea; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Penicillamine; Rats; S Phase; S-Nitrosoglutathione

2000
Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis.
    Free radical biology & medicine, 2000, Mar-01, Volume: 28, Issue:5

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cytochrome c Group; Cytosol; Free Radicals; Glutathione; Humans; Intracellular Membranes; Ketocholesterols; Kinetics; Melatonin; Membrane Potentials; Microscopy, Electron; Mitochondria; Superoxides; U937 Cells; Vitamin E

2000
Adverse effects of oxidative stress on renal cells and its prevention by antioxidants.
    Molecular urology, 2000,Spring, Volume: 4, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cell Line; Cell Survival; HSP90 Heat-Shock Proteins; Hydrogen Peroxide; Kidney Tubules, Proximal; Kinetics; Lipid Peroxidation; Malondialdehyde; Mannitol; Oxidative Stress; Pyruvates; Swine

2000
Manganese increases L-DOPA auto-oxidation in the striatum of the freely moving rat: potential implications to L-DOPA long-term therapy of Parkinson's disease.
    British journal of pharmacology, 2000, Volume: 130, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Chlorides; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis Solutions; Dopamine; Homovanillic Acid; Infusion Pumps; Levodopa; Male; Manganese; Manganese Compounds; Microdialysis; Movement; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Wistar; Time Factors; Uric Acid

2000
Effect of cigarette smoke on salivary proteins and enzyme activities.
    Archives of biochemistry and biophysics, 2000, Jul-15, Volume: 379, Issue:2

    Topics: Acetylcysteine; Acid Phosphatase; Amylases; Antioxidants; Ascorbic Acid; Blood Proteins; Deferoxamine; Female; Glutathione; Humans; L-Lactate Dehydrogenase; Male; Nicotiana; Plants, Toxic; Saliva; Salivary Proteins and Peptides; Smoke; Smoking; Time Factors

2000
Fenretinide-induced caspase 3 activity involves increased protein stability in a mechanism distinct from reactive oxygen species elevation.
    Cancer research, 2000, Aug-15, Volume: 60, Issue:16

    Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Apoptosis; Ascorbic Acid; Caspase 3; Caspases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activators; Enzyme Inhibitors; Enzyme Precursors; Enzyme Stability; Fenretinide; HL-60 Cells; Humans; Hydrogen Peroxide; Precipitin Tests; Reactive Oxygen Species

2000
Stimulation of hepatocyte growth factor production by ascorbic acid and its stable 2-glucoside.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 1998, Volume: 8, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cells, Cultured; Child; Child, Preschool; Drug Synergism; Epidermal Growth Factor; Female; Fibroblasts; Gene Expression Regulation; Glutathione; Hepatocyte Growth Factor; Humans; Indolizines; Skin

1998
Antioxidative treatment retards progression of idiopathic membranous nephropathy.
    Nephron, 2000, Volume: 86, Issue:2

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; beta Carotene; Complement Membrane Attack Complex; Disease Progression; Glomerulonephritis, Membranous; Humans; Kidney; Male; Selenium; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin E

2000
U373-MG response to interleukin-1beta-induced oxidative stress.
    Cell biology and toxicology, 2000, Volume: 16, Issue:3

    Topics: Acetylcysteine; Apolipoproteins E; Ascorbic Acid; Astrocytoma; Blotting, Western; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Free Radical Scavengers; gamma-Glutamyltransferase; Glutathione; Humans; Interleukin-1; Oxidative Stress; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Tumor Cells, Cultured; Vitamin E

2000
Interactions between N-acetylcysteine and ascorbic acid in modulating mutagenesis and carcinogenesis.
    International journal of cancer, 2000, Dec-01, Volume: 88, Issue:5

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Carcinogenicity Tests; Cell Transformation, Neoplastic; Chromium; Drug Stability; Female; Lung Neoplasms; Mice; Mutagenesis; Urethane

2000
Antioxidant compounds interfere with the 3.
    Cancer detection and prevention, 2000, Volume: 24, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Colorimetry; Coloring Agents; Culture Media; Dithiothreitol; Kinetics; Melatonin; Mercaptoethanol; Oxidation-Reduction; Pyrrolidines; Pyrrolidonecarboxylic Acid; Reagent Kits, Diagnostic; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Thiazolidines; Thiocarbamates; Vitamin E

2000
N-acetylcysteine or trolox derivative mitigate the toxic effects of methanol on the antioxidant system of rat brain.
    Toxicology, 2000, Dec-07, Volume: 156, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Brain; Chromans; Glutathione; Glutathione Peroxidase; Male; Methanol; Piperazines; Rats; Rats, Wistar; Superoxide Dismutase

2000
Activation of heat shock factor 1 by pyrrolidine dithiocarbamate is mediated by its activities as pro-oxidant and thiol modulator.
    Biochemical and biophysical research communications, 2001, Feb-23, Volume: 281, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Fibroblasts; Glutathione Disulfide; Heat Shock Transcription Factors; Heat-Shock Proteins; Oxidants; Propyl Gallate; Pyrrolidines; Sulfhydryl Compounds; Thiocarbamates; Transcription Factors

2001
Analysis of S-nitroso-N-acetylpenicillamine effects on dopamine release in the striatum of freely moving rats: role of endogenous ascorbic acid and oxidative stress.
    British journal of pharmacology, 2001, Volume: 132, Issue:4

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Corpus Striatum; Dopamine; Iron; Male; Microdialysis; Nitric Oxide Donors; Oxidative Stress; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine

2001
Lipid peroxidation product 4-hydroxy-2-nonenal acts synergistically with serotonin in inducing vascular smooth muscle cell proliferation.
    Atherosclerosis, 2001, Volume: 155, Issue:1

    Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Aorta, Thoracic; Arteriosclerosis; Ascorbic Acid; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Drug Synergism; Hydroquinones; Indoles; Lipid Peroxidation; Lysergic Acid; Male; Mitogens; Muscle, Smooth, Vascular; Pertussis Toxin; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Serotonin; Serotonin Antagonists; Virulence Factors, Bordetella; Vitamin E

2001
Antioxidant prevention of Heinz body formation and oxidative injury in cats.
    American journal of veterinary research, 2001, Volume: 62, Issue:3

    Topics: Acetylcysteine; Anemia, Hemolytic; Animals; Antioxidants; Ascorbic Acid; Cat Diseases; Cats; Eating; Female; Free Radical Scavengers; Glutathione; Heinz Bodies; Hematocrit; Male; Propylene Glycol; Prospective Studies; Random Allocation; Specific Pathogen-Free Organisms; Vitamin E

2001
Scavenger treatment of free radical injury in familial amyloidotic polyneuropathy: a study on Swedish transplanted and non-transplanted patients.
    Scandinavian journal of clinical and laboratory investigation, 2001, Volume: 61, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Aldehydes; Amyloid; Amyloid Neuropathies; Ascorbic Acid; Biopsy; Body Mass Index; Female; Free Radical Scavengers; Free Radicals; Humans; Immunohistochemistry; Lipid Peroxidation; Liver Transplantation; Male; Middle Aged; Nutritional Status; Oxidative Stress; Sweden; Treatment Outcome; Vitamin E

2001
Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:3

    Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Ascorbic Acid; Cells, Cultured; Chelating Agents; Chromans; Ditiocarb; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Onium Compounds; Oxygen Consumption; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vasoconstrictor Agents

2001
[Induction by ethanol of 'phenomenon of switching estrogen effect' and its correction].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2001, Volume: 87, Issue:4

    Topics: Acetylcysteine; Alcohol Drinking; Animals; Antioxidants; Ascorbic Acid; Carnosine; Cell Division; Comet Assay; DNA Damage; Estradiol; Female; Melatonin; Ovariectomy; Rats; Swimming; Uterus; Vitamin E

2001
Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells.
    Blood, 2001, Aug-01, Volume: 98, Issue:3

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cell Death; Drug Synergism; Glutathione; Humans; Hydrogen Peroxide; Multiple Myeloma; Oxides; Plasma Cells; Superoxides; Tumor Cells, Cultured

2001
Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy.
    Diabetes, 2001, Volume: 50, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Chromans; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet; Dietary Supplements; Galactosemias; Male; Pericytes; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases; Selenium; Vitamin E

2001
Physiologic concentrations of magnesium and placental apoptosis: prevention by antioxidants.
    Obstetrics and gynecology, 2001, Volume: 98, Issue:2

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Culture Techniques; DNA Fragmentation; Female; Humans; Keratins; Magnesium; Magnesium Chloride; Magnesium Sulfate; Placenta; Plasminogen Activator Inhibitor 2; Pregnancy; Vitamin E

2001
Kojic acid, a potential inhibitor of NF-kappaB activation in transfectant human HaCaT and SCC-13 cells.
    Archives of pharmacal research, 2001, Volume: 24, Issue:4

    Topics: Acetylcysteine; Ascorbic Acid; Cell Line; Down-Regulation; Free Radical Scavengers; Humans; Indicators and Reagents; Keratinocytes; Melanins; Mycotoxins; NF-kappa B; Pyrones; Transfection; Ultraviolet Rays

2001
Thrombin causes vascular endothelial growth factor expression in vascular smooth muscle cells: role of reactive oxygen species.
    Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:9

    Topics: Acetylcysteine; Angioplasty, Balloon; Animals; Antioxidants; Arterial Occlusive Diseases; Ascorbic Acid; Cells, Cultured; Endothelial Growth Factors; Fibroblast Growth Factor 2; Humans; Kinetics; Lymphokines; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Thrombin; Transcriptional Activation; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Corpus Striatum; Deferoxamine; Dialysis Solutions; Dopamine; Dose-Response Relationship, Drug; Free Radical Scavengers; Homovanillic Acid; Iron; Male; Metalloporphyrins; Molsidomine; Movement; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Uric Acid

2001
The antioxidant effect of rebamipide on oxygen free radical production by H. pylori-activated human neutrophils: in comparison with N-acetylcysteine, ascorbic acid and glutathione.
    Pharmacological research, 2001, Volume: 44, Issue:4

    Topics: Acetylcysteine; Alanine; Antioxidants; Ascorbic Acid; Glutathione; Helicobacter pylori; Humans; Luminescent Measurements; Neutrophil Activation; Neutrophils; Pyrogallol; Quinolones; Reactive Oxygen Species

2001
Effect of iron and manganese on hydroxyl radical production by 6-hydroxydopamine: mediation of antioxidants.
    Free radical biology & medicine, 2001, Oct-15, Volume: 31, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Corpus Striatum; Cysteine; Female; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Iron; Manganese; Oxidation-Reduction; Oxidopamine; Rats; Rats, Sprague-Dawley

2001
Ascorbic acid and N-acetylcysteine improve in vitro the function of lymphocytes from mice with endotoxin-induced oxidative stress.
    Free radical research, 2001, Volume: 35, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cell Adhesion; Cells, Cultured; Chemotaxis; Escherichia coli; Female; In Vitro Techniques; Lipopolysaccharides; Lymphocytes; Mice; Mice, Inbred BALB C; Oxidative Stress; Phagocytosis; Reactive Oxygen Species; Shock, Septic; Tumor Necrosis Factor-alpha

2001
Glutamate induces oxidative stress not mediated by glutamate receptors or cystine transporters: protective effect of melatonin and other antioxidants.
    Journal of pineal research, 2001, Volume: 31, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Brain; Carrier Proteins; Cystine; Glutamic Acid; Glutathione; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Receptors, Glutamate

2001
Modification of uterotropic effect of estrogens by whole-body gamma-irradiation.
    Bulletin of experimental biology and medicine, 2001, Volume: 132, Issue:2

    Topics: Acetylcysteine; alpha-Tocopherol; Animals; Ascorbic Acid; Carcinogens; Carnosine; Cell Nucleus; Cholesterol; DNA Damage; Dose-Response Relationship, Radiation; Estradiol; Female; Gamma Rays; Melatonin; Organ Size; Rats; Rats, Inbred Strains; Swimming; Time Factors; Uterus; Whole-Body Irradiation

2001
In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knocko
    Archives of biochemistry and biophysics, 2002, Jan-15, Volume: 397, Issue:2

    Topics: Acetylcysteine; Animals; Apoptosis; Ascorbic Acid; Dexamethasone; gamma-Glutamyltransferase; Glutathione; Mice; Mice, Knockout; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Thymus Gland

2002
UV-B-induced formation of reactive oxygen species and oxidative damage of the cyanobacterium Anabaena sp.: protective effects of ascorbic acid and N-acetyl-L-cysteine.
    Journal of photochemistry and photobiology. B, Biology, 2002, Volume: 66, Issue:2

    Topics: Acetylcysteine; Anabaena; Antioxidants; Ascorbic Acid; Chlorophyll; DNA Damage; DNA, Bacterial; Free Radical Scavengers; Lipid Peroxidation; Oxidative Stress; Photosynthesis; Reactive Oxygen Species; Ultraviolet Rays

2002
Differential modulation of apoptosis and necrosis by antioxidants in immunosuppressed human lymphocytes.
    Toxicology and applied pharmacology, 2002, Apr-15, Volume: 180, Issue:2

    Topics: Acetylcysteine; Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antioxidants; Apoptosis; Ascorbic Acid; Cyclosporine; Dexamethasone; Glucocorticoids; Humans; Immunosuppressive Agents; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Lectins, C-Type; Lymphocyte Activation; Lymphocytes; Male; Necrosis; Phytohemagglutinins; Superoxides

2002
Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay.
    Planta medica, 2002, Volume: 68, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Breast Neoplasms; Cell Division; Cell Survival; Drug Interactions; Estrogens, Non-Steroidal; Flavonoids; Humans; Isoflavones; Kaempferols; Phytoestrogens; Plant Extracts; Plant Preparations; Plants; Quercetin; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin E

2002
Intracellular antioxidant activity is necessary to modulate the macrophage response to endotoxin.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Coagulation Factors; Butylated Hydroxyanisole; Cells, Cultured; Chromans; Endotoxins; F2-Isoprostanes; Inflammation; Macrophages, Alveolar; Male; Rabbits; Reactive Oxygen Species; Respiratory Distress Syndrome; Signal Transduction; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2002
Preconditioning with millimolar concentrations of vitamin C or N-acetylcysteine protects L6 muscle cells insulin-stimulated viability and DNA synthesis under oxidative stress.
    Life sciences, 2002, Aug-30, Volume: 71, Issue:15

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cell Death; Cell Survival; Cells, Cultured; Culture Media; DNA; DNA Fragmentation; Free Radical Scavengers; Free Radicals; Histocytochemistry; Insulin; Mitochondria, Muscle; Mitogens; Muscle, Skeletal; Nucleosomes; Oxidative Stress; Rats; Reactive Oxygen Species

2002
N-Acetylcysteine, vitamin C and vitamin E diminish homocysteine thiolactone-induced apoptosis in human promyeloid HL-60 cells.
    The Journal of nutrition, 2002, Volume: 132, Issue:8

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Folic Acid; HL-60 Cells; Homocysteine; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Vitamin E

2002
A basic study of some normoxic polymer gel dosimeters.
    Physics in medicine and biology, 2002, Oct-07, Volume: 47, Issue:19

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Models, Chemical; Organophosphorus Compounds; Oxygen; Phantoms, Imaging; Phosphates; Polymers; Radiometry; Radiotherapy, Conformal; Sensitivity and Specificity; Time Factors

2002
Antioxidants inhibit endothelin-1 (1-31)-induced proliferation of vascular smooth muscle cells via the inhibition of mitogen-activated protein (MAP) kinase and activator protein-1 (AP-1).
    Biochemical pharmacology, 2002, Nov-15, Volume: 64, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cell Division; Cyclic N-Oxides; DNA; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Onium Compounds; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Time Factors; Transcription Factor AP-1

2002
Diabetes-induced activation of caspase-3 in retina: effect of antioxidant therapy.
    Free radical research, 2002, Volume: 36, Issue:9

    Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antioxidants; Apoptosis; Ascorbic Acid; beta Carotene; Caspase 3; Caspases; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelium, Vascular; Enzyme Activation; Glucose; In Vitro Techniques; Male; Oxidative Stress; Pericytes; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Retina; Selenium; Thiobarbituric Acid Reactive Substances

2002
Photoprotection by antioxidants against UVB-radiation-induced damage in pig skin organ culture.
    Radiation research, 2003, Volume: 159, Issue:2

    Topics: Acetylcysteine; Administration, Topical; alpha-Tocopherol; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Biological Availability; Culture Techniques; Epidermis; Glutathione; Lipid Peroxidation; Skin; Skin Diseases; Swine; Thioctic Acid; Treatment Outcome; Ultraviolet Rays

2003
Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor alpha, dopamine and beta-amyloid peptide 1-42.
    Free radical research, 2002, Volume: 36, Issue:11

    Topics: Acetylcysteine; Amyloid beta-Peptides; Antioxidants; Apoptosis; Ascorbic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Dopamine; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Membrane Potentials; Mitochondria; Neurons; Peptide Fragments; Tumor Necrosis Factor-alpha

2002
Protective effect of N-acetylcysteine against gamma ray induced damages in rats--biochemical evaluations.
    Indian journal of experimental biology, 2002, Volume: 40, Issue:2

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Catalase; Cell Membrane; Creatine Kinase; Cytosol; Free Radicals; Gamma Rays; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Intestines; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Rats; Sulfhydryl Reagents; Superoxide Dismutase; Time Factors; Transaminases; Vitamin A; Vitamin E

2002
Acetaminophen toxicosis in a Dalmatian.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2003, Volume: 44, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Ascorbic Acid; Dog Diseases; Dogs; Emergency Treatment; Female; Fluid Therapy; Free Radical Scavengers; Liver; Methemoglobinemia; Sodium Bicarbonate; Treatment Outcome

2003
Photoprotective properties of a hydrophilic extract of the fern Polypodium leucotomos on human skin cells.
    Journal of photochemistry and photobiology. B, Biology, 2003, Volume: 70, Issue:1

    Topics: Acetylcysteine; Ascorbic Acid; Cell Adhesion; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Chromans; Cytoskeleton; Fibroblasts; Humans; Plant Extracts; Polypodium; Protective Agents; Skin; Ultraviolet Rays

2003
Modification of the uterotropic effect produced by estrogens in aging rats.
    Bulletin of experimental biology and medicine, 2002, Volume: 134, Issue:5

    Topics: Acetylcysteine; Aging; Animals; Ascorbic Acid; Carnosine; DNA Damage; Endometrium; Estradiol; Female; Melatonin; Organ Size; Rats; Receptors, Progesterone; Swimming; Uterus; Vitamin E

2002
Cadmium induces apoptosis in anterior pituitary cells that can be reversed by treatment with antioxidants.
    Toxicology and applied pharmacology, 2003, Jul-01, Volume: 190, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cadmium; Caspases; Cell Survival; Chromans; DNA Fragmentation; Free Radical Scavengers; Hormones; Immunohistochemistry; Male; Oxidative Stress; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Vitamin E

2003
Nitric oxide alleviates oxidative damage in the green alga Chlorella pyrenoidosa caused by UV-B radiation.
    Folia microbiologica, 2003, Volume: 48, Issue:3

    Topics: Acetylcysteine; Ascorbic Acid; Catalase; Chlorella; Chlorophyll; Dithiothreitol; Glutathione; Nitric Oxide; Nitroprusside; Oxidative Stress; Phenylalanine Ammonia-Lyase; Superoxide Dismutase; Ultraviolet Rays

2003
A combination of alpha-tocopherol, vitamin C and N-acetyl cysteine increases unsaturated fatty acid levels in hydrogen peroxide-induced Candida tropicalis (ATCC 13803).
    Cell biochemistry and function, 2003, Volume: 21, Issue:3

    Topics: Acetylcysteine; alpha-Tocopherol; Analysis of Variance; Ascorbic Acid; Candida tropicalis; Cell Division; Data Interpretation, Statistical; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Hydrogen Peroxide; Lipids

2003
Effects of N-acetyl-L-cysteine and glutathione on antioxidant status of human serum and 3T3 fibroblasts.
    Journal of Korean medical science, 2003, Volume: 18, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Catalase; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Humans; Mice; NIH 3T3 Cells; Paraquat; Reactive Oxygen Species; Serum

2003
In vitro effect of manganese chloride exposure on reactive oxygen species generation and respiratory chain complexes activities of mitochondria isolated from rat brain.
    Toxicology in vitro : an international journal published in association with BIBRA, 2004, Volume: 18, Issue:1

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Brain; Chlorides; Cytochromes c; Dose-Response Relationship, Drug; Drug Combinations; Electron Transport; Glutathione; Manganese Compounds; Membrane Potentials; Mitochondria; NADH, NADPH Oxidoreductases; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rhodamine 123; Succinate Dehydrogenase; Ubiquinone

2004
Vitamin C downregulates interleukin-18 production by increasing reactive oxygen intermediate and mitogen-activated protein kinase signalling in B16F10 murine melanoma cells.
    Melanoma research, 2003, Volume: 13, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blotting, Western; Cell Line, Tumor; Densitometry; Down-Regulation; Enzyme Inhibitors; Flow Cytometry; Imidazoles; Immunoprecipitation; Interleukin-18; MAP Kinase Signaling System; Melanoma; Mice; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Skin Neoplasms; Time Factors

2003
The influence of antimicrobial peptides and mucolytics on the integrity of biofilms consisting of bacteria and yeasts as affecting voice prosthetic air flow resistances.
    Biofouling, 2003, Volume: 19, Issue:6

    Topics: Acetylcysteine; Airway Resistance; Anti-Infective Agents, Local; Ascorbic Acid; Bacteria; Biofilms; Chlorhexidine; Colony Count, Microbial; Expectorants; Humans; Larynx, Artificial; Microscopy, Electron, Scanning; Models, Anatomic; Saliva, Artificial; Triclosan; Yeasts

2003
Systemic administration of N-acetylcysteine protects dopaminergic neurons against 6-hydroxydopamine-induced degeneration.
    Journal of neuroscience research, 2004, May-15, Volume: 76, Issue:4

    Topics: Acetylcysteine; Animals; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Ascorbic Acid; Avian Proteins; Basigin; Blood Proteins; Cell Count; Corpus Striatum; Cysteine; Dopamine; Drug Administration Routes; Female; Fluoresceins; Fluorescent Dyes; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxydopamines; Immunohistochemistry; Membrane Glycoproteins; Nerve Degeneration; Neurons; Organic Chemicals; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase

2004
[Switching off the estrogen effect and approaches to its correction].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:8

    Topics: Acetylcysteine; Aging; Animals; Antioxidants; Ascorbic Acid; Carnosine; Cell Cycle; DNA Damage; Estradiol; Estrogen Receptor Modulators; Estrogens; Ethanol; Female; Fulvestrant; Gamma Rays; Melatonin; Organ Size; Ovariectomy; Physical Conditioning, Animal; Rats; Smoking; Swimming; Uterus; Vitamin D

2003
4-Hydroxy tempol-induced impairment of mitochondrial function and augmentation of glucose transport in vascular endothelial and smooth muscle cells.
    Biochemical pharmacology, 2004, May-15, Volume: 67, Issue:10

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Biological Transport; Cattle; Cell Membrane; Chromans; Cyclic N-Oxides; Endothelium, Vascular; Glucose; Glucose Transporter Type 1; Guanidines; Mitochondria; Monosaccharide Transport Proteins; Myocytes, Smooth Muscle; RNA, Messenger; Spin Labels

2004
The peroxisome proliferator BR931 kills FaO cells by p53-dependent apoptosis.
    Life sciences, 2004, Jun-04, Volume: 75, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c; Cytosol; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Genes, p53; Humans; In Situ Nick-End Labeling; Liver Neoplasms, Experimental; Mitochondria; Peroxisome Proliferators; Phosphorylation; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Rats; Time Factors

2004
Transforming growth factor Beta1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species.
    Free radical biology & medicine, 2004, Jul-15, Volume: 37, Issue:2

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Azoles; Blotting, Northern; Blotting, Western; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Culture Media, Serum-Free; Cycloheximide; DNA-Binding Proteins; Down-Regulation; Free Radicals; Growth Substances; Humans; Hydrogen Peroxide; Isoindoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Oligonucleotides, Antisense; Organoselenium Compounds; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; RNA; RNA, Messenger; Signal Transduction; Smad2 Protein; Species Specificity; Time Factors; Tissue Inhibitor of Metalloproteinase-3; Trans-Activators; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine.
    Toxicology, 2004, Aug-05, Volume: 200, Issue:2-3

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Cell Separation; Cell Survival; Chromatography, High Pressure Liquid; Deoxyepinephrine; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hallucinogens; Hepatocytes; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Spectrophotometry, Ultraviolet

2004
The evaluation of the protective action of antioxidants on small intestine of rabbits experimentally injured by ischemia and reperfusion.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Edema; Hemorrhage; Intestinal Mucosa; Intestine, Small; Ischemia; Ligation; Male; Mannitol; Mesenteric Artery, Superior; Oxidative Stress; Rabbits; Reperfusion Injury

2004
Induction of PC12 cell differentiation by flavonoids is dependent upon extracellular signal-regulated kinase activation.
    Journal of neurochemistry, 2004, Volume: 90, Issue:5

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Blotting, Western; Cell Differentiation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Flavonols; Free Radical Scavengers; GTP Phosphohydrolases; Mitogen-Activated Protein Kinases; Nerve Growth Factor; PC12 Cells; Phosphorylation; ras Proteins; Rats; Time Factors

2004
Protection of Ewing's sarcoma family tumor (ESFT) cell line SK-N-MC from betulinic acid induced apoptosis by alpha-DL-tocopherol.
    Toxicology letters, 2004, Nov-02, Volume: 153, Issue:2

    Topics: Acetylcysteine; alpha-Tocopherol; Annexin A5; Antioxidants; Apoptosis; Ascorbic Acid; Betulinic Acid; Cell Line; Cell Line, Tumor; Cell Survival; Humans; Membrane Potentials; Mitochondria; Pentacyclic Triterpenes; Reactive Oxygen Species; Sarcoma, Ewing; Triterpenes

2004
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Nucleus; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Histones; Humans; Hydroxyl Radical; Image Processing, Computer-Assisted; Immunoblotting; Immunoprecipitation; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Radiation, Ionizing; Reactive Oxygen Species; Serine; Signal Transduction; Threonine; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin

2004
Combination with water-soluble antioxidants increases the anticancer activity of quercetin in human leukemia cells.
    Die Pharmazie, 2004, Volume: 59, Issue:11

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Cell Proliferation; Cell Survival; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Indicators and Reagents; Leukemia; Lipid Peroxidation; Malondialdehyde; Quercetin; Reactive Oxygen Species; Solubility

2004
Activation of the oxidative burst by yeast elicitor in Catharanthus roseus cells occurs independently of the activation of genes involved in alkaloid biosynthesis.
    Plant molecular biology, 2004, Volume: 55, Issue:6

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Ascorbic Acid; Blotting, Northern; Calcium; Catharanthus; Cells, Cultured; Culture Media; Gadolinium; Gene Expression Regulation, Plant; Lanthanum; Models, Biological; Nifedipine; Phosphorylation; Reactive Oxygen Species; RNA, Plant; Secologanin Tryptamine Alkaloids; Yeasts

2004
Modulation of light-induced skin tumors by N-acetylcysteine and/or ascorbic acid in hairless mice.
    Carcinogenesis, 2005, Volume: 26, Issue:3

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Female; Mice; Mice, Hairless; Skin Neoplasms; Ultraviolet Rays

2005
Antioxidants and trichostatin A synergistically protect against in vitro cytotoxicity of Ni2+ in human hepatoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2005, Volume: 19, Issue:2

    Topics: Acetylation; Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione; Hepatocytes; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Liver Neoplasms; Nickel; Reactive Oxygen Species

2005
Antioxidants inhibit fatty acid and glucose-mediated induction of neutral endopeptidase gene expression in human microvascular endothelial cells.
    Journal of the American College of Surgeons, 2005, Volume: 200, Issue:2

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Glucose; Humans; Hydrogen Peroxide; Linoleic Acid; Neprilysin; Oleic Acid; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Vitamin E

2005
Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells.
    Die Pharmazie, 2005, Volume: 60, Issue:1

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Cell Proliferation; Cell Survival; Curcumin; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Indicators and Reagents; Leukemia; Lipid Peroxidation; Malondialdehyde; Oxidants; Reactive Oxygen Species

2005
Accelerated growth and prolonged lifespan of adipose tissue-derived human mesenchymal stem cells in a medium using reduced calcium and antioxidants.
    Stem cells and development, 2005, Volume: 14, Issue:1

    Topics: Acetylcysteine; Adipocytes; Adipose Tissue; Antioxidants; Ascorbic Acid; Calcium; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cellular Senescence; Chondrocytes; Culture Media; Humans; Mesenchymal Stem Cells; Osteoblasts

2005
Characterization of the formation and localization of sulfamethoxazole and dapsone-associated drug-protein adducts in human epidermal keratinocytes.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Acetylcysteine; Anti-Infective Agents; Antioxidants; Ascorbic Acid; Cell Line; Chromatography, High Pressure Liquid; Dapsone; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epidermal Cells; Epidermis; Folic Acid Antagonists; Haptens; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Keratinocytes; Microscopy, Confocal; Microscopy, Fluorescence; Protein Binding; Proteins; Sulfamethoxazole

2005
Generation and destruction of unstable reagent in flow injection system: determination of acetylcysteine in pharmaceutical formulations using bromine as reagent.
    Journal of pharmaceutical and biomedical analysis, 2005, Apr-01, Volume: 37, Issue:4

    Topics: Acetylcysteine; Ascorbic Acid; Bromine; Calibration; Chemistry, Pharmaceutical; Dehydroascorbic Acid; Flow Injection Analysis; Indicators and Reagents; Oxidation-Reduction; Pharmaceutical Solutions; Spectrophotometry, Ultraviolet

2005
Hexavalent chromium ingestion: biological markers of nephrotoxicity and genotoxicity.
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adolescent; Ascorbic Acid; beta 2-Microglobulin; Biomarkers; Charcoal; Chromium; Creatinine; Deoxyguanosine; DNA Damage; Female; Humans; Kidney Tubules, Proximal; Oxidation-Reduction; Poisoning; Potassium Dichromate; Retinol-Binding Proteins; Suicide, Attempted

2005
The effect of N-acetyl-l-cysteine and ascorbic acid on visible-light-irradiated camphorquinone/N,N-dimethyl-p-toluidine-induced oxidative stress in two immortalized cell lines.
    Biomaterials, 2005, Volume: 26, Issue:31

    Topics: 3T3 Cells; Acetylcysteine; Animals; Ascorbic Acid; Cell Line; Composite Resins; Dental Cementum; Dental Materials; Drug Interactions; Light; Mice; Oxidative Stress; Reactive Oxygen Species; Terpenes

2005
Radical mediators and mitogen-activated protein kinase signaling in oxygen-dependent radiosensitivity of human tumor cell lines.
    Free radical biology & medicine, 2005, Jul-15, Volume: 39, Issue:2

    Topics: Acetylcysteine; Anthracenes; Antioxidants; Apoptosis; Ascorbic Acid; Butadienes; Cell Line, Tumor; Cell Proliferation; DNA Damage; Enzyme Inhibitors; Fluoresceins; HeLa Cells; Humans; Imidazoles; MAP Kinase Signaling System; Melatonin; Mitochondria; Nitriles; Nitrites; Oxazines; Oxygen; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Radiation Tolerance; Rhodamines; Spectrometry, Fluorescence; Xanthenes

2005
Intravenous antioxidant modulation of end-organ damage in L-arginine-induced experimental acute pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2005, Volume: 5, Issue:4-5

    Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Antioxidants; Arginine; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Therapy, Combination; Injections, Intravenous; Lung; Male; Pancreas; Pancreatitis; Peroxidase; Proteins; Rats; Rats, Sprague-Dawley; Selenium; Time Factors

2005
Oxidative stress in Graves' disease patients and antioxidant protection against lymphocytes DNA damage in vitro.
    Die Pharmazie, 2005, Volume: 60, Issue:9

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Comet Assay; DNA Damage; Female; Graves Disease; Humans; Indicators and Reagents; Lymphocytes; Male; Malondialdehyde; Melatonin; Oxidative Stress; Quercetin; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2005
Anti-angiogenic effects of a nutrient mixture on human umbilical vein endothelial cells.
    Oncology reports, 2005, Volume: 14, Issue:6

    Topics: Acetylcysteine; Angiogenesis Inhibitors; Arginine; Ascorbic Acid; Capillaries; Cell Line; Cell Movement; Cell Proliferation; Copper; Culture Media; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Lysine; Manganese; Matrix Metalloproteinase 2; Plant Extracts; Proline; Selenium; Tea; Umbilical Veins

2005
Apoptosis induction by Epican Forte in HTLV-1 positive and negative malignant T-cells.
    Leukemia research, 2006, Volume: 30, Issue:7

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arginine; Ascorbic Acid; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Copper; Dietary Supplements; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Profiling; Human T-lymphotropic virus 1; Humans; Lysine; Manganese; Proline; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Sensitivity and Specificity; Structure-Activity Relationship; T-Lymphocytes; Transforming Growth Factors

2006
Dietary rescue of fumble--a Drosophila model for pantothenate-kinase-associated neurodegeneration.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:6

    Topics: Acetylcysteine; Adenosine Triphosphate; Animal Feed; Animals; Ascorbic Acid; Carnitine; Cloning, Molecular; Creatine; Diet; Disease Models, Animal; Drosophila; Drosophila melanogaster; Edetic Acid; Ginkgo biloba; Heterozygote; Humans; Inosine; Iron; Mutation; Neurodegenerative Diseases; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Transgenes; Vitamin E

2005
Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents.
    International journal of radiation oncology, biology, physics, 2006, Apr-01, Volume: 64, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cells, Cultured; Coenzymes; Epithelial Cells; Fluoresceins; Humans; Oxidative Stress; Radiation Protection; Selenomethionine; Thioctic Acid; Tocopherols; Ubiquinone; Vitamin E

2006
Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats.
    World journal of gastroenterology, 2006, Jan-14, Volume: 12, Issue:2

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Ascorbic Acid; Ceruletide; Female; Lipid Peroxidation; Liver; Melatonin; Pancreatitis; Rats; Rats, Wistar; Reactive Oxygen Species

2006
Lipopolysaccharide downregulates the expressions of intestinal pregnane X receptor and cytochrome P450 3a11.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Catalysis; Cytochrome P-450 CYP3A; Dexamethasone; Down-Regulation; Female; Gene Expression; Intestine, Small; Lipid Peroxidation; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred ICR; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2006
The effect of N-acetylcysteine in combination with vitamin C on the activity of ornithine decarboxylase of lung carcinoma cells--In vitro.
    Life sciences, 2006, Jul-10, Volume: 79, Issue:7

    Topics: Acetylcysteine; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Lung Neoplasms; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; RNA, Neoplasm; Thymidine

2006
Contrast-induced nephropathy: pharmacological prophylaxis.
    Kidney international. Supplement, 2006, Issue:100

    Topics: Acetylcysteine; Acute Kidney Injury; Antioxidants; Ascorbic Acid; Calcium Channel Blockers; Contrast Media; Dopamine; Humans; Kidney; Kidney Diseases; Randomized Controlled Trials as Topic; Vasoconstriction

2006
Metabolism of acrylamide to glycidamide and their cytotoxicity in isolated rat hepatocytes: protective effects of GSH precursors.
    Archives of toxicology, 2006, Volume: 80, Issue:12

    Topics: Acetylcysteine; Acrylamide; Animals; Ascorbic Acid; Biotransformation; Carcinogens; Cell Survival; Cytochrome P-450 CYP2E1; Cytoprotection; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Glutathione Transferase; Hepatocytes; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Methionine; Models, Biological; Protective Agents; Rats; Rats, Sprague-Dawley

2006
Damage Thresholds for Exposure to NIR and Blue Lasers in an In Vitro RPE Cell System.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:7

    Topics: Acetylcysteine; Ascorbic Acid; Cell Line; Cell Survival; Coculture Techniques; Computer Simulation; DNA-Binding Proteins; Humans; Lasers; Melanosomes; Phagocytosis; Pigment Epithelium of Eye; Radiation Tolerance; Telomerase; Transfection

2006
Ultrastructural clues for the protective effect of ascorbic acid and N-acetylcysteine against oxidative damage on caerulein-induced pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2006, Volume: 6, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Ceruletide; Female; Gastrointestinal Agents; Oxidative Stress; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley

2006
Role of oxidative stress in the apoptosis of hepatocellular carcinoma induced by combination of arsenic trioxide and ascorbic acid.
    Acta pharmacologica Sinica, 2006, Volume: 27, Issue:8

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Free Radical Scavengers; Humans; Liver Neoplasms; Oxidative Stress; Oxides; Proto-Oncogene Proteins c-bcl-2

2006
Uric acid determination in the presence of ascorbic acid using self-assembled submonolayer of dimercaptothiadiazole-modified gold electrodes.
    Analytical biochemistry, 2006, Oct-15, Volume: 357, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; Electrochemistry; Electrodes; Gold; Models, Molecular; Thiadiazoles; Uric Acid

2006
Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells.
    Die Pharmazie, 2006, Volume: 61, Issue:8

    Topics: Acetylation; Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Drug Synergism; Histones; HL-60 Cells; Humans; Hydroxamic Acids; Indicators and Reagents; L-Lactate Dehydrogenase; Leukemia, Promyelocytic, Acute; Protein Synthesis Inhibitors; Reactive Oxygen Species

2006
Norepinephrine induces apoptosis in neonatal rat endothelial cells via a ROS-dependent JNK activation pathway.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:11

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Apoptosis; Ascorbic Acid; Down-Regulation; Endothelial Cells; Enzyme Activation; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase Kinases; Myocardium; NADPH Oxidases; Norepinephrine; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Adrenergic; Signal Transduction

2006
Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells.
    Apoptosis : an international journal on programmed cell death, 2007, Volume: 12, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Fragmentation; Enzyme Activation; Humans; Liver Neoplasms; MAP Kinase Kinase 4; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Thioctic Acid; Tumor Suppressor Protein p53

2007
Cadmium inhibits delta-aminolevulinate dehydratase from rat lung in vitro: interaction with chelating and antioxidant agents.
    Chemico-biological interactions, 2007, Jan-30, Volume: 165, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Benzene Derivatives; Cadmium Chloride; Chelating Agents; Chlorides; Dithiothreitol; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Environmental Pollutants; Enzyme Inhibitors; Lung; Male; Organoselenium Compounds; Porphobilinogen Synthase; Rats; Rats, Wistar; Succimer; Unithiol; Zinc Compounds

2007
Thiol-oxidant monochloramine mobilizes intracellular Ca2+ in parietal cells of rabbit gastric glands.
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Calcium; Calcium Signaling; Calcium-Binding Proteins; Calcium-Transporting ATPases; Chelating Agents; Chloramines; Cytoplasm; Dithiothreitol; Dose-Response Relationship, Drug; Ethylenediamines; Fluorescent Dyes; Fura-2; In Vitro Techniques; Metals, Heavy; Microscopy, Fluorescence; Oxidants; Oxidation-Reduction; Oxidative Stress; Parietal Cells, Gastric; Rabbits; Sulfhydryl Compounds; Time Factors

2007
Inhibiting pollen reduced nicotinamide adenine dinucleotide phosphate oxidase-induced signal by intrapulmonary administration of antioxidants blocks allergic airway inflammation.
    The Journal of allergy and clinical immunology, 2007, Volume: 119, Issue:3

    Topics: Acetylcysteine; Administration, Inhalation; Animals; Antioxidants; Ascorbic Acid; Bronchitis; Chloride Channels; Hypersensitivity; Interleukin-13; Interleukin-4; Lung; Mice; Mucins; Nitrate Reductase (NAD(P)H); Plant Extracts; Pollen; Reactive Oxygen Species; Tocopherols

2007
Effects of combinations of ROS scavengers on oxidative DNA damage caused by visible-light-activated camphorquinone/N,N-dimethyl-p-toluidine.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2007, Volume: 83, Issue:2

    Topics: Acetylcysteine; Ascorbic Acid; DNA; DNA Damage; Free Radical Scavengers; Glutathione; Light; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Terpenes; Toluidines; Vitamin E

2007
Protective effects of caffeic acid phenethyl ester, vitamin C, vitamin E and N-acetylcysteine on vancomycin-induced nephrotoxicity in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:5

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Blood Urea Nitrogen; Caffeic Acids; Catalase; Disease Models, Animal; Drinking; Drug Combinations; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Kidney Diseases; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Vancomycin; Vitamin E; Water Supply

2007
Effect of antioxidant supplementation on semen quality and reactive oxygen species of frozen-thawed canine spermatozoa.
    Theriogenology, 2007, Jul-15, Volume: 68, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Catalase; Cryopreservation; Dogs; Male; Reactive Oxygen Species; Semen; Sperm Motility; Spermatozoa; Taurine; Vitamin E

2007
Pro-apoptotic effects of 1'-acetoxychavicol acetate in human breast carcinoma cells.
    Toxicology letters, 2007, Sep-28, Volume: 173, Issue:3

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Ascorbic Acid; Benzyl Alcohols; Breast Neoplasms; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromans; Dose-Response Relationship, Drug; Enzyme Induction; Female; Humans; Terpenes; Time Factors

2007
HIF-dependent antitumorigenic effect of antioxidants in vivo.
    Cancer cell, 2007, Volume: 12, Issue:3

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Cell Line; Genomic Instability; Humans; Hypoxia-Inducible Factor 1; Mice; Mice, Transgenic; Mutation

2007
Inhibition of glioma cell line A-172 MMP activity and cell invasion in vitro by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:2

    Topics: Acetylcysteine; Amino Acids; Antineoplastic Agents; Arginine; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Drug Combinations; Glioma; Humans; Laminin; Lysine; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Plant Extracts; Proline; Proteoglycans

2007
Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:5

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Arginine; Ascorbic Acid; Ceruletide; Female; Liver Diseases; Melatonin; Pancreatitis; Pentoxifylline; Rats; Rats, Wistar; Statistics, Nonparametric

2008
N-acetylcysteine protects dental pulp stromal cells from HEMA-induced apoptosis by inducing differentiation of the cells.
    Free radical biology & medicine, 2007, Nov-15, Volume: 43, Issue:10

    Topics: Acetylcysteine; Alkaline Phosphatase; Apoptosis; Ascorbic Acid; Cell Differentiation; Cell Proliferation; Cytoprotection; Dental Pulp; Free Radical Scavengers; Gene Expression; Humans; Methacrylates; NF-kappa B; Stromal Cells; Vascular Endothelial Growth Factor A; Vitamin E

2007
Alginate- and gellan-based edible films for probiotic coatings on fresh-cut fruits.
    Journal of food science, 2007, Volume: 72, Issue:4

    Topics: Acetylcysteine; Alginates; Anti-Bacterial Agents; Ascorbic Acid; Bifidobacterium; Carica; Citric Acid; Feasibility Studies; Food Handling; Food Preservation; Fruit; Glucuronic Acid; Glycerol; Hexuronic Acids; Malus; Permeability; Plant Oils; Polysaccharides, Bacterial; Probiotics; Refrigeration; Solubility; Sunflower Oil; Surface Properties; Volatilization; Water

2007
Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells.
    Cancer biology & therapy, 2007, Volume: 6, Issue:11

    Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA Breaks, Double-Stranded; Drug Resistance, Multiple; Etoposide; Glutathione; Humans; Hydrogen Peroxide; K562 Cells; Naphthoquinones; Reactive Oxygen Species

2007
Zinc deficiency-induced iron accumulation, a consequence of alterations in iron regulatory protein-binding activity, iron transporters, and iron storage proteins.
    The Journal of biological chemistry, 2008, Feb-22, Volume: 283, Issue:8

    Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Apoferritins; Ascorbic Acid; Gene Expression Regulation; Iron; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Mice; Nitric Oxide; Receptors, Transferrin; Response Elements; RNA, Messenger; Zinc

2008
Trans, trans-2,4-decadienal induced cell proliferation via p27 pathway in human bronchial epithelial cells.
    Toxicology and applied pharmacology, 2008, Apr-01, Volume: 228, Issue:1

    Topics: Acetylcysteine; Aldehydes; Antioxidants; Ascorbic Acid; Blotting, Western; Bronchi; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; DNA, Complementary; Epithelial Cells; Gene Expression Regulation; Humans; Phosphorylation; Reactive Oxygen Species; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

2008
Inhibition of 7,12-dimethylbenzanthracene-induced skin tumors by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Amino Acids; Animals; Arginine; Ascorbic Acid; Camellia sinensis; Carcinogens; Copper; Diet; Female; Keratoacanthoma; Lysine; Manganese; Mice; Mice, Inbred SENCAR; Papilloma; Plant Extracts; Proline; Selenium; Skin; Skin Neoplasms

2008
Multimodality prevention of contrast-induced acute kidney injury.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 51, Issue:2

    Topics: Acetylcysteine; Acute Kidney Injury; Antioxidants; Ascorbic Acid; Biomarkers; Cell Death; Cell Hypoxia; Consensus; Contrast Media; Creatinine; Epithelial Cells; Fluid Therapy; Humans; Inflammation; Infusions, Intravenous; Kidney Tubules; Multicenter Studies as Topic; Oxidative Stress; Practice Guidelines as Topic; Protective Agents; Randomized Controlled Trials as Topic; Renal Circulation; Treatment Outcome

2008
Supplementation with antioxidants fails to increase the total antioxidant capacity of several cell lines in culture.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2008, Volume: 62, Issue:3

    Topics: Acetylcysteine; Antimetabolites; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Cell Line; Chromatography, High Pressure Liquid; Electrochemistry; Ferric Compounds; Free Radical Scavengers; Glutathione; Humans; Keratinocytes; Proteins; Reactive Oxygen Species; Uric Acid

2008
Oxidative status of red blood cells, neutrophils, and platelets in paroxysmal nocturnal hemoglobinuria.
    Experimental hematology, 2008, Volume: 36, Issue:4

    Topics: Acetylcysteine; Anemia; Antioxidants; Ascorbic Acid; Biomarkers; Blood Platelets; Erythrocytes; Female; Flow Cytometry; Hemoglobinuria, Paroxysmal; Humans; Hydrogen Peroxide; Male; Neutrophils; Oxidants; Oxidative Stress; Reference Values; Thrombosis; Tocopherols

2008
Optimizing proliferation and characterization of multipotent stem cells from porcine adipose tissue.
    Biotechnology and applied biochemistry, 2008, Volume: 51, Issue:Pt 4

    Topics: Acetylcysteine; Adipocytes; Adipose Tissue; Animals; Ascorbic Acid; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Chondrocytes; Culture Media; Female; Gap Junctions; Multipotent Stem Cells; Neurons; Osteoblasts; Swine

2008
Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations.
    Radiation research, 2008, Volume: 169, Issue:4

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Bystander Effect; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Flow Cytometry; Fluoresceins; Reactive Oxygen Species

2008
Tetracycline-induced reproductive toxicity in male rats: effects of vitamin C and N-acetylcysteine.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 60, Issue:1

    Topics: Acetylcysteine; Administration, Oral; Animals; Anti-Bacterial Agents; Ascorbic Acid; Catalase; Drug Therapy, Combination; Free Radical Scavengers; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Transferase; Male; Organ Size; Oxidative Stress; Rats; Sperm Count; Sperm Motility; Spermatozoa; Superoxide Dismutase; Testicular Diseases; Testis; Testosterone; Tetracycline

2008
A nutrient mixture prevents acetaminophen hepatic and renal toxicity in ICR mice.
    Human & experimental toxicology, 2008, Volume: 27, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Ascorbic Acid; Aspartate Aminotransferases; Blood Urea Nitrogen; Creatinine; Kidney; Liver; Lysine; Male; Mice; Mice, Inbred ICR; Organ Size; Proline; Tea

2008
DNA-binding activity of NF-kappaB and phosphorylation of p65 are induced by N-acetylcysteine through phosphatidylinositol (PI) 3-kinase.
    Molecular immunology, 2008, Volume: 45, Issue:15

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Agammaglobulinaemia Tyrosine Kinase; Antioxidants; Ascorbic Acid; Cell Line; Cell Nucleus; DNA; Humans; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Reactive Oxygen Species; Signal Transduction; Thiourea; Transcription Factor RelA

2008
Suppression of influenza A virus nuclear antigen production and neuraminidase activity by a nutrient mixture containing ascorbic acid, green tea extract and amino acids.
    BioFactors (Oxford, England), 2007, Volume: 31, Issue:1

    Topics: Acetylcysteine; Animals; Antigens, Viral; Ascorbic Acid; Cell Line; Cell Survival; Chlorocebus aethiops; Culture Media; Dogs; Flavonoids; Influenza A virus; Lysine; Neuraminidase; Nucleocapsid Proteins; Phenols; Polyphenols; Proline; RNA-Binding Proteins; Tea; Vero Cells; Viral Core Proteins

2007
Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production.
    Neuro endocrinology letters, 2008, Volume: 29, Issue:5

    Topics: Acetophenones; Acetylcysteine; Ascorbic Acid; Blotting, Western; Cell Differentiation; Embryonal Carcinoma Stem Cells; Flow Cytometry; Free Radical Scavengers; Genes, Reporter; Glutathione; Humans; Neurons; Onium Compounds; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Tretinoin; Vitamins

2008
Effects of vitamin E and C on placental oxidative stress: an in vitro evidence for the potential therapeutic or prophylactic treatment of preeclampsia.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2008, Volume: 4, Issue:6

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endothelin-1; Female; Glutathione; Humans; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Vitamin E; Young Adult

2008
The effects of N-acetylcysteine and vitamin C on liver and pulmonary tissue damage in rats following bile duct ligation.
    Saudi medical journal, 2008, Volume: 29, Issue:11

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Bile Ducts; Liver; Lung; Male; Rats; Rats, Sprague-Dawley

2008
Glutathione metabolism under high-altitude stress and effect of antioxidant supplementation.
    Aviation, space, and environmental medicine, 2008, Volume: 79, Issue:12

    Topics: Acetylcysteine; Adaptation, Physiological; Adult; Altitude; Antioxidants; Ascorbic Acid; Dietary Supplements; Erythrocytes; Free Radical Scavengers; Free Radicals; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Male; Oxidative Stress; Prospective Studies; Reactive Oxygen Species; Stress, Physiological; Tocopherols

2008
Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2009, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Bronchi; Cell Separation; Cells, Cultured; Chelating Agents; Chlorides; DNA-Binding Proteins; Epithelial Cells; Ethylamines; Flow Cytometry; Fluorescent Dyes; Humans; Metallothionein; Mice; Mice, Knockout; Nickel; Polycyclic Compounds; Pyridines; Pyrimidines; Reactive Oxygen Species; RNA, Messenger; Time Factors; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Transfection; Up-Regulation; Zinc Compounds

2009
Polarized spectroscopic elucidation of N-acetyl-L-cysteine, L-cysteine, L-cystine, L-ascorbic acid and a tool for their determination in solid mixtures.
    Amino acids, 2010, Volume: 38, Issue:1

    Topics: Acetylcysteine; Ascorbic Acid; Cysteine; Cystine; Molecular Structure; Spectrophotometry, Infrared; Spectrum Analysis, Raman

2010
Effect of acute vs chronic H2O2-induced oxidative stress on antioxidant enzyme activities.
    Free radical research, 2009, Volume: 43, Issue:4

    Topics: Acetylcysteine; Aconitate Hydratase; Antioxidants; Ascorbic Acid; Catalase; Glutathione Peroxidase; HeLa Cells; Humans; Hydrogen Peroxide; Kinetics; Oxidative Stress; Superoxide Dismutase

2009
Mutations in the C. elegans succinate dehydrogenase iron-sulfur subunit promote superoxide generation and premature aging.
    Journal of molecular biology, 2009, Apr-03, Volume: 387, Issue:3

    Topics: Acetylcysteine; Aging, Premature; Amino Acid Sequence; Animals; Animals, Genetically Modified; Antioxidants; Ascorbic Acid; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Respiration; DNA Mutational Analysis; Herbicides; Humans; Life Expectancy; Models, Molecular; Molecular Sequence Data; Mutation; Oxidative Stress; Paraquat; Phenotype; Protein Conformation; Protein Subunits; Reactive Oxygen Species; Sequence Alignment; Succinate Dehydrogenase; Superoxides

2009
Comparison of bee products based on assays of antioxidant capacities.
    BMC complementary and alternative medicine, 2009, Feb-26, Volume: 9

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Bees; Caffeic Acids; Chromans; Cinnamates; Coumaric Acids; Fatty Acids; Fatty Acids, Monounsaturated; Free Radical Scavengers; Phenylpropionates; Plant Extracts; Pollen; Propolis; Quinic Acid; Trichothecenes

2009
Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects.
    Free radical biology & medicine, 2009, Jul-01, Volume: 47, Issue:1

    Topics: Acetylcysteine; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catalase; Cell Death; Cell Growth Processes; Cell Line, Tumor; Drug Dosage Calculations; Drug Synergism; Female; Free Radical Scavengers; Humans; Infusions, Parenteral; Liver Neoplasms, Experimental; Mice

2009
Inhibition of cellular invasive parameters in influenza A virus-infected MDCK and Vero cells by a nutrient mixture.
    BioFactors (Oxford, England), 2008, Volume: 33, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; Arginine; Ascorbic Acid; Cell Line; Cell Movement; Cell Survival; Chlorocebus aethiops; Dogs; Influenza A virus; Lysine; Matrix Metalloproteinase 9; Orthomyxoviridae Infections; Plant Extracts; Tea; Vero Cells

2008
2,4-Dinitrofluorobenzene modifies cellular proteins and induces macrophage inflammatory protein-2 gene expression via reactive oxygen species production in RAW 264.7 cells.
    Immunological investigations, 2009, Volume: 38, Issue:2

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Cell Line; Cell Survival; Chemokine CXCL2; Dermatitis, Contact; Dinitrofluorobenzene; Free Radical Scavengers; Gene Expression; Hypersensitivity, Delayed; Mice; Mitogen-Activated Protein Kinases; Peroxidase; Proteins; Reactive Oxygen Species; Skin; Vitamins

2009
Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium.
    Toxicology, 2009, Jun-30, Volume: 261, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetophenones; Acetylcysteine; Animals; Antioxidants; Arsenites; Ascorbic Acid; Cacodylic Acid; Carcinogens; Cell Line; Cell Proliferation; Cytoprotection; Deoxyguanosine; Diet; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hyperplasia; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred F344; Sodium Compounds; Urinary Bladder; Urothelium

2009
Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine.
    Free radical biology & medicine, 2009, Apr-15, Volume: 46, Issue:8

    Topics: Acetylcysteine; Antioxidants; Arginase; Arginine; Ascorbic Acid; Azoles; Catalase; Cell Death; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen Peroxide; Isoindoles; Leukemia; Organoselenium Compounds

2009
A mechanistic study of the effects of antioxidants on the formation of malondialdehyde-like products in the reaction of hydroxyl radicals with deoxyribose.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2009, Aug-03, Volume: 15, Issue:31

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Deoxyribose; Hydroxyl Radical; Malondialdehyde; Sulfhydryl Compounds; Thermodynamics

2009
Acute naphthalene poisoning following the non-accidental ingestion of mothballs.
    Singapore medical journal, 2009, Volume: 50, Issue:8

    Topics: Acetylcysteine; Adult; Anemia, Hemolytic; Ascorbic Acid; Erythrocyte Transfusion; Female; Hemolysis; Humans; Methemoglobinemia; Methylene Blue; Naphthalenes; Poisoning; Suicide, Attempted; Time Factors; Treatment Outcome

2009
Effects of reactive oxygen species scavenger on the protective action of 100% oxygen treatment against sterile inflammation in mice.
    Shock (Augusta, Ga.), 2010, Volume: 33, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cytokines; Free Radical Scavengers; Heart; Inflammation; Kidney; Liver; Lung; Male; Mice; Multiple Organ Failure; Myocardium; Oxygen; Reactive Oxygen Species; Sepsis; Thiourea; Zymosan

2010
Genotoxic effects of carotenoid breakdown products in human retinal pigment epithelial cells.
    Current eye research, 2009, Volume: 34, Issue:9

    Topics: Acetylcysteine; alpha-Tocopherol; Apoptosis; Ascorbic Acid; Carotenoids; Cell Line; Cell Proliferation; Cell Survival; Comet Assay; DNA; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Humans; Lutein; Microscopy, Fluorescence; Retinal Pigment Epithelium; Time Factors

2009
Reduction of oxidative DNA fragmentation by ascorbic acid, zinc and N-acetylcysteine in nasal mucosa tissue cultures.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Acetylcysteine; Ascorbic Acid; Cell Survival; DNA Fragmentation; Humans; Nasal Mucosa; Organ Culture Techniques; Oxidative Stress; Zinc

2009
Is there a role for antioxidants in prevention of pulmonary hypoplasia in nitrofen-induced rat model of congenital diaphragmatic hernia?
    Pediatric surgery international, 2010, Volume: 26, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Drug Synergism; Female; Fetus; Free Radical Scavengers; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lipid Peroxidation; Lung; Lung Diseases; Male; Maternal-Fetal Exchange; Pesticides; Phenyl Ethers; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vitamin E

2010
Propyl gallate inhibits the growth of calf pulmonary arterial endothelial cells via glutathione depletion.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cattle; Endothelial Cells; Endothelium, Vascular; Glutathione; Growth Inhibitors; Humans; Propyl Gallate; Pulmonary Artery; Reactive Oxygen Species

2010
Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Cell Proliferation; Gallic Acid; Glutathione; Humans; Lung Neoplasms; Oxidative Stress; Reactive Oxygen Species

2010
Evaluation of anti-oxidant treatments in an in vitro model of alkaptonuric ochronosis.
    Rheumatology (Oxford, England), 2010, Volume: 49, Issue:10

    Topics: Acetylcysteine; Alkaptonuria; Antioxidants; Ascorbic Acid; Cells, Cultured; Coumaric Acids; Homogentisic Acid; Humans; Ochronosis; Oxidative Stress; Phytic Acid; Protein Carbonylation; Taurine; Thioctic Acid

2010
Evaluation of antioxidant drugs for the treatment of ochronotic alkaptonuria in an in vitro human cell model.
    Journal of cellular physiology, 2010, Volume: 225, Issue:1

    Topics: Acetylcysteine; Alkaptonuria; Antioxidants; Apoptosis; Ascorbic Acid; Cartilage, Articular; Cell Proliferation; Cell Survival; Cells, Cultured; Chondrocytes; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Ochronosis; Protein Carbonylation

2010
Surface treatments and coatings to maintain fresh-cut mango quality in storage.
    Journal of the science of food and agriculture, 2010, Volume: 90, Issue:13

    Topics: Acetylcysteine; Ascorbic Acid; Carboxymethylcellulose Sodium; Carrageenan; Chemical Phenomena; Chitosan; Citric Acid; Food Handling; Food Microbiology; Food Preservation; Food Preservatives; Fruit; Humans; Hydrogen-Ion Concentration; Maillard Reaction; Mangifera; Pigmentation; Quality Control; Sensation; Time Factors

2010
Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells.
    Glia, 2010, Nov-15, Volume: 58, Issue:15

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Astrocytes; Brain; Caspase 3; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Hemin; Humans; L-Lactate Dehydrogenase; Mice; Microvessels; Neuroprotective Agents; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Time Factors

2010
Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease.
    PloS one, 2010, Nov-17, Volume: 5, Issue:11

    Topics: Acetylcysteine; Alkaloids; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Ascorbic Acid; Benzodioxoles; Brain; Catechin; Cerebral Cortex; Cognition; Curcumin; Dietary Supplements; Folic Acid; Hippocampus; Humans; Immunoblotting; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Piperidines; Polyunsaturated Alkamides; Thioctic Acid; Vitamin B Complex; Vitamins

2010
N-acetylcysteine attenuates dimethylnitrosamine induced oxidative stress in rats.
    European journal of pharmacology, 2011, Mar-05, Volume: 654, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Carcinogens; Catalase; Dimethylnitrosamine; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E

2011
Central antioxidant therapy inhibits parasympathetic baroreflex control in conscious rats.
    Neuroscience letters, 2011, Feb-04, Volume: 489, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Baroreflex; Heart Rate; Injections, Intraventricular; Male; Nitroprusside; Parasympathetic Nervous System; Phenylephrine; Rats; Rats, Wistar; Reactive Oxygen Species; Vasoconstrictor Agents; Vasodilator Agents

2011
Differential modulation of angiogenesis by advanced glycation end products.
    Experimental biology and medicine (Maywood, N.J.), 2011, Volume: 236, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Aorta, Thoracic; Ascorbic Acid; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane; Chromones; Glycation End Products, Advanced; Humans; Morpholines; Neovascularization, Pathologic; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Umbilical Veins; Vascular Endothelial Growth Factor A

2011
A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans.
    PLoS biology, 2010, Dec-07, Volume: 8, Issue:12

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Flow Cytometry; Longevity; Mitochondrial Proteins; Models, Biological; Paraquat; Reactive Oxygen Species; Receptor, Insulin; Signal Transduction; Superoxides

2010
Oxidative stress-induced membrane shedding from RBCs is Ca flux-mediated and affects membrane lipid composition.
    The Journal of membrane biology, 2011, Volume: 240, Issue:2

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Calcimycin; Calcium; Cholesterol; Erythrocyte Membrane; Flow Cytometry; Humans; Ionophores; Membrane Lipids; Nuclear Magnetic Resonance, Biomolecular; Osmotic Pressure; Oxidants; Oxidative Stress; Phagocytosis; Phosphatidylserines; Phospholipids; tert-Butylhydroperoxide; Thalassemia

2011
Novel cytochrome p450 bioactivation of a terminal phenyl acetylene group: formation of a one-carbon loss benzaldehyde and other oxidative products in the presence of N-acetyl cysteine or glutathione.
    Chemical research in toxicology, 2011, May-16, Volume: 24, Issue:5

    Topics: Acetylcysteine; Acetylene; Animals; Antioxidants; Ascorbic Acid; Benzaldehydes; Cattle; Chelating Agents; Cytochrome P-450 Enzyme System; Deferoxamine; Dogs; Glutathione; Humans; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

2011
β-Catenin mediates cyclic strain-stimulated cardiomyogenesis in mouse embryonic stem cells through ROS-dependent and integrin-mediated PI3K/Akt pathways.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:7

    Topics: Acetylcysteine; Androstadienes; Animals; Antioxidants; Ascorbic Acid; beta Catenin; Cell Culture Techniques; Cell Differentiation; Cell Line; Connexin 43; Embryoid Bodies; Embryonic Stem Cells; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Integrin alpha5beta1; Mice; Myocytes, Cardiac; Periodicity; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Stress, Mechanical; Transcription Factors; Wortmannin

2011
Oxidative stress augments the secretion of atrial natriuretic peptide in isolated rat atria.
    Peptides, 2011, Volume: 32, Issue:6

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Atrial Natriuretic Factor; Cardiovascular Diseases; Extracellular Fluid; Guanidines; Heart Atria; Hemodynamics; Hydrogen Peroxide; Male; Mitogen-Activated Protein Kinase Kinases; Myocardial Contraction; Organ Culture Techniques; Oxidative Stress; Propyl Gallate; Pyrogallol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sodium-Hydrogen Exchangers; Sulfones

2011
Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds.
    FEBS letters, 2011, Apr-20, Volume: 585, Issue:8

    Topics: Acetylcysteine; alpha-Synuclein; Antioxidants; Apigenin; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Humans; Iron Chelating Agents; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Structure; Mutation; Parkinson Disease; Phenols; Polyphenols; Protein Multimerization; Protein Structure, Quaternary; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship

2011
Delayed treatment with vitamin C and N-acetyl-L-cysteine protects Schwann cells without compromising the anti-myeloma activity of bortezomib.
    International journal of hematology, 2011, Volume: 93, Issue:6

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Autophagy; Boronic Acids; Bortezomib; Cell Line; Endoplasmic Reticulum; Free Radical Scavengers; Multiple Myeloma; Neuroprotective Agents; Peripheral Nervous System Diseases; Pyrazines; Rats; Schwann Cells

2011
Carbon tetrachloride: a hepatotoxin causes oxidative stress in murine peritoneal macrophage and peripheral blood lymphocyte cells.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:1

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Free Radical Scavengers; Lipid Peroxidation; Lymphocytes; Macrophages, Peritoneal; Mice; Oxidative Stress; Superoxides

2012
Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart.
    Free radical research, 2011, Volume: 45, Issue:10

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Biopterins; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2011
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice.
    Molecular vision, 2011, Volume: 17

    Topics: Acetylcysteine; Administration, Topical; Aging; Animals; Arginine; Ascorbic Acid; Biological Transport, Active; Cataract; Crystallins; Gene Knock-In Techniques; Glycation End Products, Advanced; Guanidines; Humans; Lens, Crystalline; Mass Spectrometry; Mice; Mice, Transgenic; Ophthalmic Solutions; Penicillamine; Rabbits; Sodium-Coupled Vitamin C Transporters; Spectrometry, Fluorescence

2011
Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, and N-acetylcysteine in chicken embryo model.
    Toxicology, 2012, Jan-27, Volume: 291, Issue:1-3

    Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Ascorbic Acid; Chick Embryo; Chromatography, High Pressure Liquid; Folic Acid; Foot Deformities; Glutathione; Hindlimb; Histone Deacetylases; Homocysteine; Hydrogen Peroxide; Joints; Muscle, Skeletal; Neovascularization, Physiologic; Superoxide Dismutase; Teratogens; Tissue Embedding; Valproic Acid; Vitamins

2012
Intracellular GSH and ascorbate inhibit radical-induced protein chain peroxidation in HL-60 cells.
    Free radical biology & medicine, 2012, Jan-15, Volume: 52, Issue:2

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Cell Survival; Gamma Rays; Glutamate-Cysteine Ligase; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Proteins; Superoxides

2012
Transplacental antioxidants inhibit lung tumors in mice exposed to cigarette smoke after birth: a novel preventative strategy?
    Current cancer drug targets, 2012, Volume: 12, Issue:2

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Body Weight; Female; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Nicotiana; Placenta; Pregnancy; Reactive Oxygen Species; Smoke; Survival

2012
Effects of inorganic and organic arsenic compounds on growth and apoptosis of human T-lymphoblastoid leukemia cells.
    Anticancer research, 2011, Volume: 31, Issue:12

    Topics: Acetylcysteine; Apoptosis; Arsenic; Ascorbic Acid; Benzimidazoles; Buthionine Sulfoximine; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitory Concentration 50; Leukemia, T-Cell; Leukocytes, Mononuclear; Models, Chemical; Organic Chemicals; T-Lymphocytes; Tetrazolium Salts; Thiazoles

2011
The ratio of S-adenosylmethione and S-adenosyl-homocysteine is increased in the brains of newborn rats in a model of valproic acid teratogenicity.
    Toxicology, 2012, Mar-11, Volume: 293, Issue:1-3

    Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Ascorbic Acid; Folic Acid; Teratogens; Valproic Acid; Vitamins

2012
SVCT-2 in breast cancer acts as an indicator for L-ascorbate treatment.
    Oncogene, 2013, Mar-21, Volume: 32, Issue:12

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Autophagy; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Sodium-Coupled Vitamin C Transporters

2013
Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion.
    Oncology reports, 2012, Volume: 28, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Fibroblasts; Glutathione; Humans; Lung; Oxides; Reactive Oxygen Species; Transfection

2012
May toxicity of amiodarone be prevented by antioxidants? A cell-culture study.
    Journal of cardiothoracic surgery, 2012, Jun-28, Volume: 7

    Topics: Acetylcysteine; Amiodarone; Animals; Antioxidants; Ascorbic Acid; Cell Line, Transformed; Cell Survival; Drug Interactions; Fibroblasts; Mice; Oxidative Stress

2012
N-acetyl cysteine attenuates diazinon exposure-induced oxidative stress in rat testis.
    Andrologia, 2013, Volume: 45, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Animals; Ascorbic Acid; Diazinon; Drug Interactions; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Insecticides; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Testis; Vitamin A; Vitamin E

2013
The impact of antioxidant supplements and endurance exercise on genes of the carbohydrate and lipid metabolism in skeletal muscle of mice.
    Cell biochemistry and function, 2013, Volume: 31, Issue:1

    Topics: Acetylcysteine; Adaptation, Physiological; Animals; Antioxidants; Ascorbic Acid; Carbohydrate Metabolism; Drug Evaluation, Preclinical; Free Radical Scavengers; Gene Expression Regulation; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Muscle, Skeletal; Peroxiredoxin VI; Physical Conditioning, Animal; Physical Endurance; Random Allocation; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Ubiquinone

2013
Effect of pirfenidone on pulmonary fibrosis due to paraquat poisoning in rats.
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:8

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Disease Models, Animal; Herbicides; Injections, Intraperitoneal; Injections, Intravenous; Life Expectancy; Male; Paraquat; Pulmonary Fibrosis; Pyridones; Rats; Rats, Wistar; Survival Rate; Vitamin E

2012
[Presentation of a case of Paraquat poisoning].
    Revista espanola de anestesiologia y reanimacion, 2012, Volume: 59, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Adult; Ascorbic Acid; Charcoal; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Diuretics; Fatal Outcome; Furosemide; Gastric Lavage; Hemoperfusion; Humans; Immunosuppressive Agents; Male; Paraquat; Poisoning; Pulmonary Fibrosis; Respiration, Artificial; Respiratory Insufficiency; Rhabdomyolysis; Suicide, Attempted; Vitamin E

2012
Implication of glutathione in the in vitro antiplasmodial mechanism of action of ellagic acid.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Acetylcysteine; Animals; Antimalarials; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Cells, Cultured; Deferoxamine; Drug Synergism; Ellagic Acid; Enzyme Inhibitors; Erythrocytes; Glutathione; Humans; Inhibitory Concentration 50; Mice; Oxidation-Reduction; Plasmodium falciparum; Plasmodium yoelii; Reactive Oxygen Species; Siderophores

2012
Small sizes of TiO2-NPs exhibit adverse effects at predicted environmental relevant concentrations on nematodes in a modified chronic toxicity assay system.
    Journal of hazardous materials, 2012, Volume: 243

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Caenorhabditis elegans; Growth; Indicators and Reagents; Intestines; Motor Activity; Nanoparticles; Oxidative Stress; Particle Size; Reactive Oxygen Species; Suspensions; Titanium

2012
Suberoyl bishydroxamic acid-induced apoptosis in HeLa cells via ROS-independent, GSH-dependent manner.
    Molecular biology reports, 2013, Volume: 40, Issue:5

    Topics: Acetylcysteine; Apoptosis; Ascorbic Acid; Buthionine Sulfoximine; Caspase Inhibitors; Cell Proliferation; Glutathione; HeLa Cells; Histone Deacetylases; Humans; Hydroxamic Acids; Membrane Potential, Mitochondrial; Reactive Oxygen Species

2013
The protective effect of antioxidants on orbital fibroblasts from patients with Graves' ophthalmopathy in response to oxidative stress.
    Molecular vision, 2013, Volume: 19

    Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Cell Proliferation; Cell Survival; Female; Fibroblasts; Graves Ophthalmopathy; Humans; Hydrogen Peroxide; Interleukin-1beta; Intracellular Space; Male; Orbit; Oxidative Stress; Protective Agents; Transforming Growth Factor beta

2013
Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria.
    Rheumatology (Oxford, England), 2013, Volume: 52, Issue:9

    Topics: Acetylcysteine; Alkaptonuria; Antioxidants; Ascorbic Acid; Cell Line; Chondrocytes; Cytokines; Humans; Inflammation; Lipid Peroxidation; Phytic Acid; Serum Amyloid A Protein; Taurine; Thioctic Acid

2013
Editorial comment.
    Urology, 2013, Volume: 82, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Calcium Oxalate; Free Radical Scavengers; Kidney; Male; Oxidative Stress

2013
Preventive effect of specific antioxidant on oxidative renal cell injury associated with renal crystal formation.
    Urology, 2013, Volume: 82, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Calcium Oxalate; Cell Survival; Cholecalciferol; Crystallization; Dogs; Ethylene Glycol; Free Radical Scavengers; Kidney; Lactoylglutathione Lyase; Madin Darby Canine Kidney Cells; Male; Oxidative Stress; Rats; Rats, Wistar

2013
Anti-leukemia activity of PVP-coated silver nanoparticles via generation of reactive oxygen species and release of silver ions.
    Biomaterials, 2013, Volume: 34, Issue:32

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Antineoplastic Agents; Antioxidants; Apoptosis; Ascorbic Acid; Cell Line, Tumor; DNA Damage; Female; HL-60 Cells; Humans; Ions; Leukemia; Male; Membrane Potential, Mitochondrial; Metal Nanoparticles; Middle Aged; Reactive Oxygen Species; Silver

2013
Effects of antioxidants on DNA-double strand breaks in human gingival fibroblasts exposed to methacrylate based monomers.
    Dental materials : official publication of the Academy of Dental Materials, 2013, Volume: 29, Issue:9

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Bisphenol A-Glycidyl Methacrylate; Cell Culture Techniques; DNA Breaks, Double-Stranded; Fibroblasts; Gingiva; Histones; Humans; Hydrogen Peroxide; Methacrylates; Oxidants; Polyurethanes

2013
Superoxide generated by pyrogallol reduces highly water-soluble tetrazolium salt to produce a soluble formazan: a simple assay for measuring superoxide anion radical scavenging activities of biological and abiological samples.
    Analytica chimica acta, 2013, Sep-02, Volume: 793

    Topics: Acetylcysteine; Anions; Ascorbic Acid; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Mass Spectrometry; Pyrogallol; Serum Albumin; Spectrophotometry; Superoxide Dismutase; Superoxides; Temperature; Tetrazolium Salts; Water

2013
Control of oxidative reactions of hemoglobin in the design of blood substitutes: role of the Vc, NAC, TEMPO and their reductant system.
    Artificial cells, nanomedicine, and biotechnology, 2014, Volume: 42, Issue:4

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Blood Substitutes; Cyclic N-Oxides; Female; Hemoglobins; Humans; Oxidation-Reduction; Oxygen; Pregnancy

2014
Phosphorescence detection of L-ascorbic acid with surface-attached N-acetyl-L-cysteine and L-cysteine Mn doped ZnS quantum dots.
    Talanta, 2013, Nov-15, Volume: 116

    Topics: Acetylcysteine; Ascorbic Acid; Cysteine; Humans; Hydrogen-Ion Concentration; Kinetics; Limit of Detection; Luminescent Measurements; Manganese; Molecular Probes; Quantum Dots; Sulfides; Temperature; Zinc Compounds

2013
Gene delivery via the hybrid vector of recombinant adeno-associated virus and polyethylenimine.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Feb-14, Volume: 52

    Topics: Acetylcysteine; Androstadienes; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cytochalasin B; Dependovirus; Gene Transfer Techniques; Genetic Vectors; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyethyleneimine; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Vitamin E; Wortmannin

2014
Impact of antioxidants on the ability of phenolic phytochemicals to kill HCT116 colon cancer cells.
    Free radical research, 2014, Volume: 48, Issue:3

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Catechin; Cell Line, Tumor; Colonic Neoplasms; Curcumin; DNA Damage; Drug Interactions; Gene Expression; HCT116 Cells; Heme Oxygenase-1; HT29 Cells; Humans; Iron Chelating Agents

2014
Unsuspected pyocyanin effect in yeast under anaerobiosis.
    MicrobiologyOpen, 2014, Volume: 3, Issue:1

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Anaerobiosis; Antioxidants; Ascorbic Acid; Candida albicans; DNA, Fungal; Drug Resistance, Multiple, Fungal; Fermentation; Intercalating Agents; Mitochondria; Oxidative Stress; Pyocyanine; Resveratrol; Saccharomyces cerevisiae; Stilbenes

2014
Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells.
    Inflammation, 2014, Volume: 37, Issue:3

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Line; Cell Proliferation; Chromans; Glutathione; Humans; Hypochlorous Acid; Inflammation; Kidney; Lung; Neutrophils; Nicotine; Oxidation-Reduction; Proliferating Cell Nuclear Antigen

2014
Flavonoids and 5-aminosalicylic acid inhibit the formation of neutrophil extracellular traps.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cells, Cultured; Chemotaxis, Leukocyte; Flavonoids; Humans; Mesalamine; NADPH Oxidases; Neutrophils; Peroxidase; Phagocytosis; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

2013
Ascorbate reverses high glucose- and RAGE-induced leak of the endothelial permeability barrier.
    Biochemical and biophysical research communications, 2014, Feb-28, Volume: 445, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Benzamides; Cell Line; Cell Membrane Permeability; Cells, Cultured; Chromans; Cyclic N-Oxides; Dithiothreitol; Dose-Response Relationship, Drug; Endothelial Cells; Glucose; Glycation End Products, Advanced; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Mice; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin, Bovine; Spin Labels

2014
Inhibitory effect of N-acetyl cysteine and ascorbic acid on the development of myringosclerosis: an experimental study.
    International journal of pediatric otorhinolaryngology, 2014, Volume: 78, Issue:7

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Female; Fibrin Foam; Fibroblasts; Free Radical Scavengers; Guinea Pigs; Hemostatics; Immunohistochemistry; Inflammation; Leukocytes; Microscopy; Mucous Membrane; Myringosclerosis; Nitric Oxide Synthase; Random Allocation; Transforming Growth Factor beta; Tympanic Membrane; Vascular Endothelial Growth Factor A

2014
Silencing of BRCA2 decreases anoikis and its heterologous expression sensitizes yeast cells to acetic acid-induced programmed cell death.
    Apoptosis : an international journal on programmed cell death, 2014, Volume: 19, Issue:9

    Topics: Acetic Acid; Acetylcysteine; Anoikis; Antioxidants; Ascorbic Acid; BRCA2 Protein; Breast; Caspases; Cell Line; Cell Proliferation; Cell Survival; DNA Fragmentation; Epithelial Cells; Female; Gene Silencing; Humans; Male; Prostate; Reactive Oxygen Species; Saccharomyces cerevisiae; Thyroid Gland

2014
Protective role of L-ascorbic acid, N-acetylcysteine and apocynin on neomycin-induced hair cell loss in zebrafish.
    Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:3

    Topics: Acetophenones; Acetylcysteine; Animal Use Alternatives; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cell Survival; Embryo, Nonmammalian; Hair Cells, Auditory, Inner; Mechanoreceptors; Microscopy, Confocal; Neomycin; Oxidative Stress; Reactive Oxygen Species; Zebrafish

2015
Cytoprotective effects of amifostine, ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats.
    World journal of gastroenterology, 2014, Aug-07, Volume: 20, Issue:29

    Topics: Acetylcysteine; Amifostine; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Liver; Male; Methotrexate; Oxidative Stress; Rats, Sprague-Dawley; Time Factors

2014
Intratracheal co-administration of antioxidants and ceftriaxone reduces pulmonary injury and mortality rate in an experimental model of sepsis.
    Respirology (Carlton, Vic.), 2014, Volume: 19, Issue:7

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Ceftriaxone; Disease Models, Animal; Drug Administration Routes; Drug Therapy, Combination; Lung Injury; Male; Rats; Rats, Wistar; Sepsis; Trachea; Vitamin E

2014
Antioxidant treatment prevents serum deprivation- and TNF-α-induced endothelial dysfunction through the inhibition of NADPH oxidase 4 and the restoration of β-oxidation.
    Journal of vascular research, 2014, Volume: 51, Issue:5

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Carnitine; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Coculture Techniques; Cytokines; Cytoprotection; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Leukocytes; Mitochondria; NADPH Oxidase 4; NADPH Oxidases; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; RNA Interference; Serum; Transfection; Tumor Necrosis Factor-alpha

2014
Comparative effects of sulfhydryl compounds on target organellae, nuclei and mitochondria, of hydroxylated fullerene-induced cytotoxicity in isolated rat hepatocytes.
    Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:12

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Cell Culture Techniques; Cell Nucleus; Cell Survival; Cells, Cultured; Cysteine; DNA Damage; Fullerenes; Hepatocytes; Male; Membrane Potential, Mitochondrial; Methionine; Organelles; Rats, Inbred F344; Reactive Oxygen Species; Sulfhydryl Compounds

2015
Indoxyl sulfate-induced oxidative stress, mitochondrial dysfunction, and impaired biogenesis are partly protected by vitamin C and N-acetylcysteine.
    TheScientificWorldJournal, 2015, Volume: 2015

    Topics: Acetylcysteine; Ascorbic Acid; Cell Survival; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Indican; Mitochondria; Organelle Biogenesis; Oxidative Stress; Reactive Oxygen Species

2015
Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis.
    Scientific reports, 2015, Apr-24, Volume: 5

    Topics: Acetylcysteine; Apoptosis; Apoptosis Inducing Factor; Ascorbic Acid; bcl-2-Associated X Protein; Cell Proliferation; Cells, Cultured; Cytochromes c; Drug Synergism; Dynamins; GTP Phosphohydrolases; Histones; Humans; Hydrogen Peroxide; Mesenchymal Stem Cells; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Proteins; Necrosis; Oxidative Stress; Protective Agents; Proto-Oncogene Proteins c-bcl-2

2015
[Differential diagnostic and therapeutic aspects of Q-fever in a male prisoner. Case report].
    Orvosi hetilap, 2015, May-03, Volume: 156, Issue:18

    Topics: Acetylcysteine; Amoxicillin-Potassium Clavulanate Combination; Antibodies, Bacterial; Ascorbic Acid; Coxiella burnetii; Diagnosis, Differential; Doxycycline; Drug Therapy, Combination; Humans; Male; Middle Aged; Pneumonia, Bacterial; Prisoners; Q Fever; Silymarin; Treatment Outcome

2015
Efficacy of N-Acetylcysteine, Glutathione, and Ascorbic Acid in Acute Toxicity of Paraoxon to Wistar Rats: Survival Study.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Glutathione; Insecticides; Male; Oxidative Stress; Paraoxon; Pralidoxime Compounds; Rats; Rats, Wistar; Risk

2015
Antioxidants, endothelial dysfunction, and DCS: in vitro and in vivo study.
    Journal of applied physiology (Bethesda, Md. : 1985), 2015, Dec-15, Volume: 119, Issue:12

    Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Ascorbic Acid; Cell Death; Cell Survival; Cells, Cultured; Decompression Sickness; Diving; Endothelium, Vascular; Glutathione; Male; Nitric Oxide; Oxidative Stress; Peptidyl-Dipeptidase A; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Superoxides; Thiobarbituric Acid Reactive Substances

2015
Combination of anti-tuberculosis drugs with vitamin C or NAC against different Staphylococcus aureus and Mycobacterium tuberculosis strains.
    Microbial pathogenesis, 2016, Volume: 93

    Topics: Acetylcysteine; Antitubercular Agents; Ascorbic Acid; Drug Synergism; Drug Therapy, Combination; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Tuberculosis

2016
Antimycin A induces death of the human pulmonary fibroblast cells via ROS increase and GSH depletion.
    International journal of oncology, 2016, Volume: 48, Issue:2

    Topics: Acetylcysteine; Antimycin A; Antioxidants; Apoptosis; Ascorbic Acid; Caspase Inhibitors; Cell Death; Cell Line; Cell Proliferation; Fibroblasts; G1 Phase; Glutathione; Growth Inhibitors; Humans; Lung; Membrane Potential, Mitochondrial; Oxidative Stress; Reactive Oxygen Species

2016
Antioxidants inhibit advanced glycosylation end-product-induced apoptosis by downregulation of miR-223 in human adipose tissue-derived stem cells.
    Scientific reports, 2016, Mar-11, Volume: 6

    Topics: Acetylcysteine; Adipose Tissue; Antioxidants; Apoptosis; Ascorbic Acid; Caspase 3; Cell Proliferation; Gene Expression Regulation, Developmental; Glycation End Products, Advanced; Humans; Mesenchymal Stem Cells; MicroRNAs; Reactive Oxygen Species; Serum Albumin; Serum Albumin, Human

2016
Effects of pyrogallic acid on Microcystis aeruginosa: oxidative stress related toxicity.
    Ecotoxicology and environmental safety, 2016, Volume: 132

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; DNA Damage; Microcystis; Oxidation-Reduction; Oxidative Stress; Pyrogallol; Reactive Oxygen Species

2016
Antioxidants reveal an inverted U-shaped dose-response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans.
    Aging cell, 2017, Volume: 16, Issue:1

    Topics: Acetylcysteine; Aging; Animals; Antioxidants; Ascorbic Acid; Caenorhabditis elegans; Longevity; Mitochondria; Models, Biological; Mutation; Oxidative Stress; Paraquat; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase

2017
"Inflamm-aging" influences immune cell survival factors in human bone marrow.
    European journal of immunology, 2017, Volume: 47, Issue:3

    Topics: Acetylcysteine; Aging; Animals; Ascorbic Acid; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Cell Survival; Cells, Cultured; Cytokines; Free Radical Scavengers; Humans; Immunologic Memory; Immunosenescence; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reactive Oxygen Species; Superoxide Dismutase-1

2017
Surgically Induced Necrotizing Scleritis Following Strabismus Surgery Treated Successfully with Topical N-acetylcysteine in a Child with Congenital Fibrosis of Extraocular Muscles and Varadi Papp Syndrome.
    Strabismus, 2017, Volume: 25, Issue:1

    Topics: Acetylcysteine; Administration, Topical; Ascorbic Acid; Child; Fibrosis; Free Radical Scavengers; Humans; Male; Oculomotor Muscles; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; Ophthalmoplegia; Orofaciodigital Syndromes; Postoperative Complications; Scleritis; Strabismus

2017
Modulation of the Redox Expression and Inflammation Response in the Critically Ill Polytrauma Patient with Thoracic Injury. Statistical Correlations between Antioxidant Therapy.
    Clinical laboratory, 2016, Sep-01, Volume: 62, Issue:9

    Topics: Abbreviated Injury Scale; Acetylcysteine; Adult; Aged; Antioxidants; Ascorbic Acid; Critical Illness; Female; Humans; Incidence; Inflammation; Injury Severity Score; Length of Stay; Male; Middle Aged; Multiple Organ Failure; Multiple Trauma; Oxidation-Reduction; Oxidative Stress; Respiration, Artificial; Retrospective Studies; Sepsis; Thiamine; Thoracic Injuries

2016
Growth inhibitory effects of standard pro- and antioxidants on the human malaria parasite Plasmodium falciparum.
    Experimental parasitology, 2017, Volume: 180

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Benzothiazoles; Diamide; Diamines; Dithiothreitol; Dose-Response Relationship, Drug; Erythrocytes; Fluorescent Dyes; Host-Parasite Interactions; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Malaria, Falciparum; Organic Chemicals; Oxidants; Oxidation-Reduction; Oxidative Stress; Parasitemia; Plasmodium falciparum; Quinolines; tert-Butylhydroperoxide; Time Factors

2017
Effects of N-acetyl cysteine on oxidative stress and TNF-α gene expression in diclofenac-induced hepatotoxicity in rats.
    Toxicology mechanisms and methods, 2017, Volume: 27, Issue:8

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Catalase; Chemical and Drug Induced Liver Injury; Diclofenac; Gene Expression; Lipids; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Silymarin; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2017
Effects of N-acetylcysteine on spinal cord oxidative stress biomarkers in rats with neuropathic pain.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Oct-19, Volume: 50, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Constriction; Free Radical Scavengers; Lipid Peroxides; Male; Neuralgia; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Reproducibility of Results; Sciatic Neuropathy; Spinal Cord; Time Factors; Treatment Outcome

2017
Analysis of oxidative stress-related markers in critically ill polytrauma patients: An observational prospective single-center study.
    Bosnian journal of basic medical sciences, 2018, May-20, Volume: 18, Issue:2

    Topics: Acetylcysteine; Adult; Antioxidants; APACHE; Ascorbic Acid; Biomarkers; Critical Care; Critical Illness; Female; Humans; Inflammation; Lipid Peroxidation; Lipids; Male; Middle Aged; Multiple Trauma; Oxidative Stress; Partial Thromboplastin Time; Prospective Studies; Sepsis; Treatment Outcome

2018
A critical role for very long-chain fatty acid elongases in oleic acid-mediated Saccharomyces cerevisiae cytotoxicity.
    Microbiological research, 2018, Volume: 207

    Topics: Acetylcysteine; Acetyltransferases; Ascorbic Acid; Catalase; Cell Membrane; Fatty Acid Elongases; Glutathione; Membrane Proteins; Oleic Acid; Oxidative Stress; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2018
Visible light reduces C. elegans longevity.
    Nature communications, 2018, 03-02, Volume: 9, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Caenorhabditis elegans; Light; Longevity; Oxidative Stress; Photoperiod; Unfolded Protein Response

2018
Inhibition of Erythroid Differentiation of Human Leukemia K562 Cells by N-acetylcysteine and Ascorbic Acid through Downregulation of ROS.
    Biomedical and environmental sciences : BES, 2018, Volume: 31, Issue:3

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Differentiation; Down-Regulation; Erythroid Cells; Hemin; Humans; K562 Cells; Reactive Oxygen Species

2018
Effects of Antioxidants in Reducing Accumulation of Fat in Hepatocyte.
    International journal of molecular sciences, 2018, Aug-29, Volume: 19, Issue:9

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cell Survival; Endoplasmic Reticulum; Hep G2 Cells; Hepatocytes; Humans; Oleic Acid; Reactive Oxygen Species; Triglycerides; Xanthophylls

2018
On infusion of high-dose ascorbate in treating cancer: Is it time for N-acetylcysteine pretreatment to enhance susceptibility and to lower side effects?
    Medical hypotheses, 2019, Volume: 122

    Topics: Acetylcysteine; Administration, Intravenous; Antioxidants; Ascorbic Acid; Copper; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hyaluronic Acid; Immune System; Kidney; Neoplasms; Pancreatic Neoplasms; Sulfhydryl Compounds

2019
The mechanism for differential effect of nelfinavir and indinavir on collagen metabolism in human skin fibroblasts.
    Experimental dermatology, 2019, Volume: 28, Issue:7

    Topics: Acetylcysteine; Ascorbic Acid; Cell Survival; Collagen; Dipeptidases; DNA; Down-Regulation; Fibroblasts; Glutamine; HIV Protease Inhibitors; Humans; Indinavir; Nelfinavir; NF-kappa B p50 Subunit; Phosphatidylinositol 3-Kinases; Phosphorylation; Proline; Skin; Wortmannin

2019
l-Dehydroascorbic acid recycled by thiols efficiently scavenges non-thermal plasma-induced hydroxyl radicals.
    Archives of biochemistry and biophysics, 2019, 07-15, Volume: 669

    Topics: Acetylcysteine; Ascorbic Acid; Cyclic N-Oxides; Dehydroascorbic Acid; Dithiothreitol; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Hydroxyl Radical; Plasma Gases; Spin Labels

2019
N-acetylcysteine and ascorbic acid therapy for acute hepatic injury after hexavalent chromium ingestion.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:1

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Chromium; Drug Therapy, Combination; Humans; Male; Middle Aged; Oxidative Stress; Treatment Outcome

2020
The X
    Cellular oncology (Dordrecht), 2020, Volume: 43, Issue:1

    Topics: Acetylcysteine; Amino Acid Transport System y+; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Glutathione; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Prostatic Neoplasms; Reactive Oxygen Species; Sulfasalazine; Transplantation, Heterologous

2020
Ex vivo antioxidant preconditioning improves the survival rate of bone marrow stem cells in the presence of wound fluid.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2020, Volume: 28, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Case-Control Studies; Cell Movement; Cell Proliferation; Cell Survival; Diabetes Mellitus; Exudates and Transudates; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Obese; Osteogenesis; Prediabetic State; Transplantation, Autologous; Wounds and Injuries

2020
Effect of Different Antioxidants on X-ray Induced DNA Double-strand Breaks Using γ-H2AX in Human Blood Lymphocytes.
    Health physics, 2020, Volume: 119, Issue:1

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; beta Carotene; Blood Cells; DNA; DNA Breaks, Double-Stranded; Dose-Response Relationship, Radiation; Histones; Humans; Lymphocytes; Microscopy, Fluorescence; Radiation Dosage; Radiation, Ionizing; Radiography; Reactive Oxygen Species; Vitamin E; X-Rays

2020
N-Acetyl cysteine abrogates silver-induced reactive oxygen species in human cells without altering silver-based antimicrobial activity.
    Toxicology letters, 2020, Oct-10, Volume: 332

    Topics: Acetates; Acetylcysteine; Adenosine Triphosphate; Anti-Bacterial Agents; Ascorbic Acid; Cell Line; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; Melatonin; Microbial Sensitivity Tests; Reactive Oxygen Species; Silver; Silver Compounds; Superoxides

2020
Application of methylene blue -vitamin C -N-acetyl cysteine for treatment of critically ill COVID-19 patients, report of a phase-I clinical trial.
    European journal of pharmacology, 2020, Oct-15, Volume: 885

    Topics: Acetylcysteine; Ascorbic Acid; Clinical Trials, Phase I as Topic; Compassionate Use Trials; Coronavirus Infections; COVID-19; Critical Illness; Female; Humans; Hypoxia; Male; Methylene Blue; Middle Aged; Pandemics; Pneumonia, Viral

2020
Topical vitamin C, vitamin E, and acetylcysteine as corneal wound healing agents: A comparative study.
    Indian journal of ophthalmology, 2020, Volume: 68, Issue:12

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Cornea; Epithelium, Corneal; Female; Male; Ophthalmic Solutions; Rabbits; Vitamin E; Wound Healing

2020
Antioxidants other than vitamin C may be detected by glucose meters: Immediate relevance for patients with disorders targeted by antioxidant therapies.
    Clinical biochemistry, 2021, Volume: 92

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Blood Glucose; Blood Glucose Self-Monitoring; Glutathione; Humans; Point-of-Care Systems

2021
Disruption of disulfides within RBD of SARS-CoV-2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:6

    Topics: Acetylcysteine; Amides; Ascorbic Acid; Auranofin; COVID-19; COVID-19 Drug Treatment; Disulfides; Esters; HEK293 Cells; Humans; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Sulfhydryl Compounds; Virus Internalization

2021
Trimetazedine with hyperinsulinimea-euoglycemia, N-acetyl cysteine, and vitamin C: A new approach concept for management of aluminum phosphide poisoning.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:1

    Topics: Acetylcysteine; Aluminum Compounds; Animals; Ascorbic Acid; Hyperinsulinism; Male; Phosphines; Rabbits; Trimetazidine

2022
The Role of Mesenchymal Stem Cells with Ascorbic Acid and N-Acetylcysteine on TNF-
    Journal of diabetes research, 2021, Volume: 2021

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Body Weight; Caspase 3; Cell Proliferation; Ceruletide; Fluorescent Dyes; Insulin; Interleukin-1beta; Islets of Langerhans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; NF-kappa B; Organic Chemicals; Pancreatitis; Proliferating Cell Nuclear Antigen; Rats; Regeneration; Tumor Necrosis Factor-alpha

2021
N-Acetyl Cysteine, Selenium, and Ascorbic Acid Rescue Diabetic Cardiac Hypertrophy via Mitochondrial-Associated Redox Regulators.
    Molecules (Basel, Switzerland), 2021, Nov-30, Volume: 26, Issue:23

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Ascorbic Acid; Biomarkers; Blood Glucose; Body Weight; Calcium; Cardiomegaly; Cardiotonic Agents; Cytochromes c; Diabetic Cardiomyopathies; Disease Models, Animal; Down-Regulation; GATA4 Transcription Factor; Lipid Peroxidation; Lipids; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Selenium

2021
Cardiorespiratory and metabolic fitness indicators in novice volleyball trainees: effect of 1-week antioxidant supplementation with N-acetyl-cysteine/zinc/vitamin C.
    The Journal of international medical research, 2021, Volume: 49, Issue:12

    Topics: Acetylcysteine; Angiopoietin-Like Protein 8; Antioxidants; Ascorbic Acid; Dietary Supplements; Hepatocyte Growth Factor; Humans; Insulin; Male; Sports Nutritional Physiological Phenomena; Volleyball; Zinc

2021
IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy.
    International journal of molecular sciences, 2021, Dec-21, Volume: 23, Issue:1

    Topics: Acetylcysteine; AMP-Activated Protein Kinases; Antimycin A; Ascorbic Acid; Cell Polarity; Flow Cytometry; Humans; Interleukin-17; Macrophages; Microscopy, Confocal; Mitochondria; Mitophagy; Monocytes; Organophosphorus Compounds; Phosphorylation; Piperidines; Reactive Oxygen Species; THP-1 Cells

2021
Amelioration of Cadmium-Induced Oxidative Damage in Wistar Rats by Vitamin C, Zinc and
    Medical sciences (Basel, Switzerland), 2022, 01-26, Volume: 10, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cadmium; Oxidative Stress; Rats; Rats, Wistar; Vitamins; Zinc

2022
Proteomic Investigation of the Antibacterial Mechanism of Cefiderocol against Escherichia coli.
    Microbiology spectrum, 2022, 10-26, Volume: 10, Issue:5

    Topics: Acetylcysteine; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Deferoxamine; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Iron; NAD; NADP; Proteomics; Quinones; Reactive Oxygen Species; Siderophores; Sulfur

2022
Inhibition of the Cell Uptake of Delta and Omicron SARS-CoV-2 Pseudoviruses by
    Cells, 2022, 10-21, Volume: 11, Issue:20

    Topics: Acetylcysteine; Angiotensin-Converting Enzyme 2; Antioxidants; Ascorbic Acid; COVID-19 Drug Treatment; HEK293 Cells; Humans; Hydrogen Peroxide; Oxidants; Peptidyl-Dipeptidase A; Reactive Oxygen Species; SARS-CoV-2; Sulfhydryl Compounds

2022
ROS-lowering doses of vitamins C and A accelerate malignant melanoma metastasis.
    Redox biology, 2023, Volume: 60

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Humans; Melanoma; Melanoma, Cutaneous Malignant; Mice; Reactive Oxygen Species; Vitamin A; Vitamins

2023
The Effect of Vitamin C and
    The American journal of sports medicine, 2023, Volume: 51, Issue:6

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Biomechanical Phenomena; Collagen; Matrix Metalloproteinase 13; Rats; Rats, Sprague-Dawley; Rodentia; Rotator Cuff; Rotator Cuff Injuries; Superoxide Dismutase-1; Tendons; Wound Healing

2023
Enhancement of recombinant human interleukin-22 production by fusing with human serum albumin and supplementing N-acetylcysteine in Pichia Pastoris.
    Protein expression and purification, 2023, Volume: 212

    Topics: Acetylcysteine; Ascorbic Acid; Humans; Interleukin-22; Serum Albumin, Human

2023
Effect of Antioxidant Supplementation on NET Formation Induced by LPS In Vitro; the Roles of Vitamins E and C, Glutathione, and N-acetyl Cysteine.
    International journal of molecular sciences, 2023, Aug-24, Volume: 24, Issue:17

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Dietary Supplements; Glutathione; Glutathione Disulfide; Horses; Lipopolysaccharides; Reactive Oxygen Species; Vitamin E; Vitamins

2023
Solvation Plays a Key Role in Antioxidant-Mediated Attenuation of Elevated Creatinine Level: An In Vitro Spectroscopic Investigation.
    The journal of physical chemistry. B, 2023, 10-12, Volume: 127, Issue:40

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Creatinine; Humans; Kidney Diseases; Spectroscopy, Fourier Transform Infrared

2023