acetylcysteine and arginine

acetylcysteine has been researched along with arginine in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.82)18.7374
1990's17 (23.94)18.2507
2000's22 (30.99)29.6817
2010's28 (39.44)24.3611
2020's2 (2.82)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cherry, JD; Dudley, JP1
Dietzsch, HJ; Gottschalk, B; Heyne, K; Leupoid, W; Wunderlich, P1
Angulo, I; García, B; Medina, M; Navarro, J; Rodríguez, R; Subiza, JL1
Chen, F; Demers, LM; Gaydos, LJ; Kuhn, DC; Sun, SC1
Agvald, P; Gustafsson, LE; Persson, MG2
Lo, TW; McLellan, AC; Selwood, T; Thornalley, PJ; Westwood, ME1
Carbonell, L; Fenoy, FJ; Ferrer, P; García-Salom, M1
Broor, S; Carson, DA; Kusari, AB; Lotz, M; Richman, DD; Seth, P; Wachsman, W; Zhang, B1
Khraibi, AA; Lahera, V; Romero, JC1
Hughes, AD; Sever, PS; Sunman, W1
Arnet, U; Lüscher, TF; Siebenmann, R; Stulz, P; Turina, M; von Segesser, LK; Yang, Z1
Castagliuolo, I; LaMont, JT; Nikulasson, Z; Pothoulakis, C; Qiu, B1
Abeles, AJ; Block, ER; Patel, JM1
Aldershvile, J; Boesgaard, S; Laursen, JB; Poulsen, HE1
Benet, LZ; Berg-Candolfi, M; Candolfi, E1
Khan, M; Namboodiri, AM; Pahan, K; Sheikh, FG; Singh, I1
Anfossi, G; Massucco, P; Mattiello, L; Perna, P; Russo, I; Tassone, F; Trovati, M1
Haleva-Toledo, E; Naim, M; Rouseff, RL; Zehavi, U1
Bauer, V; Kukan, M; Machová, J; Navarová, J; Ondriás, K; Racková, L; Sinský, M; Stefek, M1
Chen, L; Smith, JB; Smith, L; Wang, Z1
Alonso, MJ; Alvarez, Y; Hernanz, R; Salaices, M; Simonsen, U; Zibrandtsen, H1
Allen, R; Boger, R; Doshi, S; Goodfellow, J; Lewis, M; McDowell, I; Moat, S; Newcombe, R; Stabler, S1
Nagaraj, RH; Staniszewska, MM1
Hardman, J; McMahon, R; Redmond, HP; Schofield, D; Shields, C; Siriwardena, AK1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW2
Abu-El-Ardat, K; Diab-Assaf, M; Harakeh, S; Khalife, J; Niedzwiecki, A; Rath, M1
Banks, S; Costello, R; Csako, G; Danner, RL; Eichacker, P; Esposito, C; Kalil, AC; Myers, DE; Natanson, C; Sevransky, JE; Sittler, KJ; Solomon, SB; Susla, GM; Vandivier, RW1
Eşrefoğlu, M; Gül, M; Turan, F1
Macarthur, H; Westfall, TC; Wilken, GH1
Andreotti, F; Coluzzi, G; Santucci, E1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
Pranawa, W; Thaha, M; Tomino, Y; Yogiantoro, M1
Berchio, A; Bergamini, S; Brocato, L; Della Casa, L; Gigliardi, VR; Iannone, A; Manzato, E; Martina, V; Masha, A; Massarenti, P; Settanni, F1
Bai, YP; Chen, YR; Jiang, DJ; Li, YJ; Shi, RZ; Tang, ZY; Xiao, HB; Zhang, GG1
Jariwalla, RJ; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, N1
Boontje, NM; de Crom, R; de Waard, MC; Dekkers, DH; Duncker, DJ; Kuster, DW; Lamers, JM; van der Velden, J; van Haperen, R1
Brown, GC; Brown, RD; Burke, GA1
Bruno, GA; Dinatale, S; Ghigo, E; Manieri, C; Martina, V; Masha, A1
Gadag, V; Gill, VD; Han, Y; Randell, E; Vasdev, S1
Melo, AC; Nesi, RT; Pimenta, WA; Porto, LC; Rueff-Barroso, CR; Silva, MA; Valença, SS1
Chen, F; Ma, J; Peng, X; Wang, M; Zhang, X1
Barreto, DV; Barreto, FC; Eloot, S; Glorieux, G; Liabeuf, S; Massy, Z; Schepers, E; Vanholder, R1
Fan, X; Monnier, VM; Nemet, I; Potts, B; Strauch, CM; Xiaoqin, L1
Büchler, MW; Gebhard, MM; Hackert, T; Hartwig, W; Kaiser, H; Klar, E; Schmidt, J; Werner, J1
Liskova, J; Melkova, Z; Shankaran, P; Vlkova, L1
Dooley, CT; Li, L; Misler, JA; Thompson, JH1
Kim, JW; Park, CH1
Ando, R; Fukami, K; Iwatani, R; Kaida, Y; Nakayama, Y; Okuda, S; Ueda, S; Yamagishi, S1
Uomo, G1
Ando, R; Fukami, K; Iwatani, R; Kaida, Y; Kaifu, K; Kusumoto, T; Nakayama, Y; Obara, N; Okuda, S; Taguchi, K; Toyonaga, M; Ueda, S; Yamagishi, S; Yokoro, M1
Ponticelli, C1
Fan, NC; Hsu, CN; Huang, LT; Tain, YL; Tsai, CM1
Atkinson, C; Kunchithapautham, K; Rohrer, B1
Jiang, L; Liu, Q; Lu, W; Wang, L; Xu, L; Zhi, Y; Zhong, L; Zhou, P3
Bui, LC; Dairou, J; Lamouri, A; Leger, T; Mihoub, M; Richarme, G1
Huang, YX; Jian, D; Li, J; Li, WZ; Shi, W; Wang, B; Xie, HF1
Da Silva, EP; Lambertucci, RH1
Chen, YS; He, J; Huang, HQ; Li, J; Li, ZL; Ouyang, LY; Ye, SB; Zeng, YX; Zhang, H; Zhang, XS1
Hsu, CN; Lee, CT; Lin, YJ; Tain, YL; Tsai, CC1
Lin, HC; Ma, L; Neu, J; Zhou, P1
He, YL; Li, XM; Nie, F; Xiong, Y; Zhou, XK1
Baum, SJ; Chakravarthy, MV; Chera, H; Gunn, NT; Harrison, SA; Kohli, A; Koziel, MJ; Patil, R; Younes, ZH; Zhao, J1

Reviews

2 review(s) available for acetylcysteine and arginine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Potential Nutrients for Preventing or Treating Bronchopulmonary Dysplasia.
    Paediatric respiratory reviews, 2017, Volume: 22

    Topics: Acetylcysteine; Antioxidants; Arginine; Bronchopulmonary Dysplasia; Citrulline; Cysteine; Fatty Acids, Unsaturated; Glutamine; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Infant, Premature; Inositol; Selenium; Vitamin A; Vitamin B Complex

2017

Trials

4 trial(s) available for acetylcysteine and arginine

ArticleYear
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Acetylcysteine; Adult; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Cystathionine; Cysteine; Dipeptides; Double-Blind Method; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Kinetics; Male; Methionine; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vasodilation

2005
Intravenous N-acetylcysteine during hemodialysis reduces asymmetric dimethylarginine level in end-stage renal disease patients.
    Clinical nephrology, 2008, Volume: 69, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Arginine; Biomarkers; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Infusions, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Treatment Outcome

2008
Long-term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes.
    Diabetes care, 2008, Volume: 31, Issue:5

    Topics: Acetylcysteine; Administration, Oral; Aged; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Endothelium, Vascular; Humans; Hypertension; Hypoglycemic Agents; Male; Middle Aged; Placebos; Systole

2008
Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease.
    The American journal of gastroenterology, 2021, 12-01, Volume: 116, Issue:12

    Topics: Acetylcysteine; Administration, Oral; Arginine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Glutamine; Humans; Isoleucine; Leucine; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Single-Blind Method; Treatment Outcome; Valine

2021

Other Studies

65 other study(ies) available for acetylcysteine and arginine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
The effect of mucolytic agents and topical decongestants on the ciliary activity of chicken tracheal organ cultures.
    Pediatric research, 1977, Volume: 11, Issue:8

    Topics: Acetylcysteine; Administration, Topical; Animals; Arginine; Carbonates; Chickens; Cilia; Culture Techniques; Deoxyribonucleases; Expectorants; Oxymetazoline; Pancreas; Phenylephrine; Sodium; Trachea; Vasoconstrictor Agents

1977
Cystic fibrosis: comparison of two mucolytic drugs for inhalation treatment (acetylcysteine and arginine hydrochloride).
    Pediatrics, 1975, Volume: 55, Issue:1

    Topics: Acetylcysteine; Aerosols; Arginine; Bronchoscopy; Carbon Dioxide; Child; Child, Preschool; Cough; Cystic Fibrosis; Drug Evaluation; Expectorants; Female; Humans; Male; Mucus; Oxygen; Radionuclide Imaging; Respiration; Respiratory Function Tests; Spirometry; Sputum

1975
Involvement of nitric oxide in bone marrow-derived natural suppressor activity. Its dependence on IFN-gamma.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Jul-01, Volume: 155, Issue:1

    Topics: Acetylcysteine; Amino Acid Oxidoreductases; Animals; Antibodies, Monoclonal; Arginine; Bone Marrow; Cell Line; Immunity, Innate; Interferon-gamma; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes, Regulatory

1995
Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages.
    Biochemical and biophysical research communications, 1995, Sep-25, Volume: 214, Issue:3

    Topics: Acetylcysteine; Alkaloids; Animals; Arginine; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Molecular Sequence Data; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotide Probes; omega-N-Methylarginine; Protein Kinase C; Silicon Dioxide; Staurosporine; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine

1995
Rapid tolerance to formation of authentic NO from nitroglycerin in vivo.
    Agents and actions. Supplements, 1995, Volume: 45

    Topics: Acetylcysteine; Animals; Arginine; Cysteine; Drug Tolerance; Glutathione; Hemodynamics; Infusions, Intravenous; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Pulmonary Circulation; Rabbits

1995
Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin.
    The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51

    Topics: Acetylcysteine; Arginine; Kinetics; Lysine; Protein Binding; Pyruvaldehyde; Serum Albumin, Bovine

1994
Role of nitric oxide on papillary blood flow and pressure natriuresis.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:3

    Topics: Acetylcysteine; Animals; Arginine; Blood Pressure; Kidney Medulla; Laser-Doppler Flowmetry; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Regional Blood Flow

1995
Detection of nitric oxide in exhaled air during administration of nitroglycerin in vivo.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Acetylcysteine; Adenosine; Animals; Arginine; Blood Pressure; Cysteine; Glutathione; Heart Rate; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Pulmonary Artery; Pulmonary Veins; Rabbits; Vascular Resistance

1994
Stimulation of HIV replication in mononuclear phagocytes by leukemia inhibitory factor.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:7

    Topics: Acetylcysteine; Arginine; Base Sequence; Cell Line; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Gene Products, gag; Growth Inhibitors; HIV; HIV Core Protein p24; Humans; Interleukin-6; Kinetics; Leukemia Inhibitory Factor; Lymphokines; Molecular Sequence Data; Monocytes; NF-kappa B; Nitric Oxide; omega-N-Methylarginine; RNA, Messenger; Signal Transduction; Transcription, Genetic; Virus Replication

1994
Sulfhydryl group donors potentiate the hypotensive effect of acetylcholine in rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:2

    Topics: Acetylcholine; Acetylcysteine; Animals; Antihypertensive Agents; Arginine; Benzoates; Blood Pressure; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfhydryl Compounds; Thimerosal

1993
Free-radical scavengers, thiol-containing reagents and endothelium-dependent relaxation in isolated rat and human resistance arteries.
    Clinical science (London, England : 1979), 1993, Volume: 84, Issue:3

    Topics: Acetylcholine; Acetylcysteine; Animals; Arginine; Arteries; Captopril; Catalase; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Female; Humans; Isometric Contraction; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vascular Resistance

1993
Development of nitrate tolerance in human arteries and veins: comparison of nitroglycerin and SPM 5185.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: Acetylcysteine; Arginine; Dipeptides; Drug Tolerance; Free Radical Scavengers; Humans; In Vitro Techniques; Isometric Contraction; Mammary Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Saphenous Vein; Vasodilator Agents

1995
Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin.
    Gastroenterology, 1996, Volume: 111, Issue:2

    Topics: Acetylcysteine; Animals; Arginine; Bacterial Toxins; Cell Degranulation; Chymases; Clostridioides difficile; Enterotoxins; Enzyme Inhibitors; Guanidines; Ileum; Indazoles; Intestinal Mucosa; Male; Mast Cells; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Permeability; Peroxidase; Rats; Rats, Wistar; Serine Endopeptidases; Vibrio cholerae

1996
Nitric oxide exposure and sulfhydryl modulation alter L-arginine transport in cultured pulmonary artery endothelial cells.
    Free radical biology & medicine, 1996, Volume: 20, Issue:5

    Topics: Acetylcysteine; Acrolein; Animals; Arginine; Biological Transport; Cells, Cultured; Dithiothreitol; Endothelium, Vascular; Ethylmaleimide; L-Lactate Dehydrogenase; Lipid Peroxidation; Nitrates; Nitric Oxide; Nitrites; Penicillamine; Pulmonary Artery; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Swine

1996
Nitrate tolerance impairs nitric oxide-mediated vasodilation in vivo.
    Cardiovascular research, 1996, Volume: 31, Issue:5

    Topics: Acetylcholine; Acetylcysteine; Animals; Arginine; Drug Tolerance; Female; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; Rats; Rats, Wistar; Vasodilation

1996
Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:4

    Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Aryl Hydrocarbon Hydroxylases; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Interferon-gamma; Intestinal Mucosa; Jejunum; Macrophages, Peritoneal; Male; Mice; Mice, Inbred CBA; Microsomes; Microsomes, Liver; Nitrites; Oxidoreductases, N-Demethylating; Toxoplasmosis, Animal

1996
Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes.
    The Journal of biological chemistry, 1998, Jan-30, Volume: 273, Issue:5

    Topics: Acetylcysteine; Alkyl and Aryl Transferases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Ceramides; Cytokines; Drug Interactions; Enzyme Induction; Flavonoids; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Neuroglia; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Kinase Inhibitors; Pyrrolidines; Rats; Signal Transduction; Sphingomyelin Phosphodiesterase; Thiocarbamates

1998
L-arginine modulates aggregation and intracellular cyclic 3,5-guanosine monophosphate levels in human platelets: direct effect and interplay with antioxidative thiol agent.
    Thrombosis research, 1999, Jun-01, Volume: 94, Issue:5

    Topics: Acetylcysteine; Antioxidants; Arginine; Blood Platelets; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Guanosine Monophosphate; Humans; Nitric Oxide; omega-N-Methylarginine; Platelet Aggregation; Platelet Aggregation Inhibitors

1999
Effects of L-cysteine and N-acetyl-L-cysteine on 4-hydroxy-2, 5-dimethyl-3(2H)-furanone (furaneol), 5-(hydroxymethyl)furfural, and 5-methylfurfural formation and browning in buffer solutions containing either rhamnose or glucose and arginine.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:10

    Topics: Acetylcysteine; Arginine; Buffers; Citrus; Cysteine; Food Additives; Food Preservation; Furaldehyde; Furans; Glucose; Humans; Maillard Reaction; Rhamnose

1999
Involvement of L-arginine-nitric oxide system in the response of isolated trachea to reactive oxygen species.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Electrolysis; Glucose; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Reactive Oxygen Species; Stereoisomerism; Thiobarbituric Acid Reactive Substances; Trachea; Tromethamine

2003
Preservation of caspase-3 subunits from degradation contributes to apoptosis evoked by lactacystin: any single lysine or lysine pair of the small subunit is sufficient for ubiquitination.
    Molecular pharmacology, 2003, Volume: 64, Issue:2

    Topics: Acetylcysteine; Apoptosis; Arginine; Caspase 3; Caspases; Cell Line, Transformed; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Precursors; HL-60 Cells; Humans; Lysine; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Subunits; Proteins; Transfection; Ubiquitin; X-Linked Inhibitor of Apoptosis Protein

2003
Measurements of nitric oxide concentration and hyporeactivity in rat superior mesenteric artery exposed to endotoxin.
    Cardiovascular research, 2004, Apr-01, Volume: 62, Issue:1

    Topics: Acetylcysteine; Animals; Arginine; Blotting, Western; Cyclooxygenase 2; Immunohistochemistry; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Male; Mesenteric Artery, Superior; Nitric Oxide; Norepinephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Superoxide Dismutase; Vasoconstriction

2004
3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody.
    The Journal of biological chemistry, 2005, Jun-10, Volume: 280, Issue:23

    Topics: Acetylcysteine; Antibodies, Monoclonal; Antigens; Arginine; Binding, Competitive; Blotting, Western; Cell Membrane; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Histidine; Humans; Immunohistochemistry; Kynurenine; Lens, Crystalline; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Ninhydrin; Oxygen; Protein Conformation; Spectrophotometry; Time Factors; Tryptophan; Water

2005
Intravenous antioxidant modulation of end-organ damage in L-arginine-induced experimental acute pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2005, Volume: 5, Issue:4-5

    Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Antioxidants; Arginine; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Therapy, Combination; Injections, Intravenous; Lung; Male; Pancreas; Pancreatitis; Peroxidase; Proteins; Rats; Rats, Sprague-Dawley; Selenium; Time Factors

2005
Anti-angiogenic effects of a nutrient mixture on human umbilical vein endothelial cells.
    Oncology reports, 2005, Volume: 14, Issue:6

    Topics: Acetylcysteine; Angiogenesis Inhibitors; Arginine; Ascorbic Acid; Capillaries; Cell Line; Cell Movement; Cell Proliferation; Copper; Culture Media; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Lysine; Manganese; Matrix Metalloproteinase 2; Plant Extracts; Proline; Selenium; Tea; Umbilical Veins

2005
Apoptosis induction by Epican Forte in HTLV-1 positive and negative malignant T-cells.
    Leukemia research, 2006, Volume: 30, Issue:7

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arginine; Ascorbic Acid; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Copper; Dietary Supplements; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Profiling; Human T-lymphotropic virus 1; Humans; Lysine; Manganese; Proline; Reverse Transcriptase Polymerase Chain Reaction; Selenium; Sensitivity and Specificity; Structure-Activity Relationship; T-Lymphocytes; Transforming Growth Factors

2006
Preclinical trial of L-arginine monotherapy alone or with N-acetylcysteine in septic shock.
    Critical care medicine, 2006, Volume: 34, Issue:11

    Topics: Acetylcysteine; Animals; Arginine; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Free Radical Scavengers; Immunotherapy; Nitric Oxide; Parenteral Nutrition; Proportional Hazards Models; Random Allocation; Shock, Septic; Survival Analysis

2006
Inhibition of glioma cell line A-172 MMP activity and cell invasion in vitro by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:2

    Topics: Acetylcysteine; Amino Acids; Antineoplastic Agents; Arginine; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Drug Combinations; Glioma; Humans; Laminin; Lysine; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Plant Extracts; Proline; Proteoglycans

2007
Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:5

    Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Arginine; Ascorbic Acid; Ceruletide; Female; Liver Diseases; Melatonin; Pancreatitis; Pentoxifylline; Rats; Rats, Wistar; Statistics, Nonparametric

2008
Oxidative stress attenuates NO-induced modulation of sympathetic neurotransmission in the mesenteric arterial bed of spontaneously hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Blood Pressure; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Neuropeptide Y; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Splanchnic Circulation; Superoxides; Sympathetic Nervous System

2008
Contrast-induced nephropathy and mortality: possible crucial role of asymmetric dimethylarginine.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2007, Volume: 8, Issue:12

    Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Antioxidants; Arginine; Biomarkers; Contrast Media; Coronary Angiography; Humans; Kidney Diseases; Nitric Oxide

2007
Inhibition of 7,12-dimethylbenzanthracene-induced skin tumors by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Amino Acids; Animals; Arginine; Ascorbic Acid; Camellia sinensis; Carcinogens; Copper; Diet; Female; Keratoacanthoma; Lysine; Manganese; Mice; Mice, Inbred SENCAR; Papilloma; Plant Extracts; Proline; Selenium; Skin; Skin Neoplasms

2008
Involvement of the endothelial DDAH/ADMA pathway in nitroglycerin tolerance: the role of ALDH-2.
    Life sciences, 2008, Mar-26, Volume: 82, Issue:13-14

    Topics: Acetylcysteine; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amidohydrolases; Arginine; Cell Line; Cyclic GMP; Drug Tolerance; Endothelial Cells; Humans; Lipid Peroxides; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroglycerin; Oxidative Stress; Reactive Oxygen Species

2008
Inhibition of cellular invasive parameters in influenza A virus-infected MDCK and Vero cells by a nutrient mixture.
    BioFactors (Oxford, England), 2008, Volume: 33, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; Arginine; Ascorbic Acid; Cell Line; Cell Movement; Cell Survival; Chlorocebus aethiops; Dogs; Influenza A virus; Lysine; Matrix Metalloproteinase 9; Orthomyxoviridae Infections; Plant Extracts; Tea; Vero Cells

2008
Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Antioxidants; Arginine; Biopterins; Disease Models, Animal; Exercise Therapy; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Physical Exertion; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Time Factors; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Pressure; Ventricular Remodeling

2009
Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine.
    Free radical biology & medicine, 2009, Apr-15, Volume: 46, Issue:8

    Topics: Acetylcysteine; Antioxidants; Arginase; Arginine; Ascorbic Acid; Azoles; Catalase; Cell Death; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen Peroxide; Isoindoles; Leukemia; Organoselenium Compounds

2009
Prolonged treatment with N-acetylcysteine and L-arginine restores gonadal function in patients with polycystic ovary syndrome.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:11

    Topics: Acetylcysteine; Adolescent; Adult; Amenorrhea; Arginine; Female; Humans; Menstruation; Oligomenorrhea; Ovary; Polycystic Ovary Syndrome; Treatment Outcome

2009
Fructose and moderately high dietary salt-induced hypertension: prevention by a combination of N-acetylcysteine and L-arginine.
    Molecular and cellular biochemistry, 2010, Volume: 337, Issue:1-2

    Topics: Acetylcysteine; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Fructose; Heart; Hypertension; Kidney; Liver; Myocardium; Organ Size; Rats; Rats, Inbred WKY; Sodium Chloride, Dietary

2010
L-NAME and L-arginine differentially ameliorate cigarette smoke-induced emphysema in mice.
    Pulmonary pharmacology & therapeutics, 2011, Volume: 24, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Male; Mice; Mice, Inbred C57BL; Neutrophils; NG-Nitroarginine Methyl Ester; Nicotiana; Nitric Oxide; Oxidants; Oxidative Stress; Pulmonary Emphysema; Smoke; Smoking

2011
Dual effects of phloretin and phloridzin on the glycation induced by methylglyoxal in model systems.
    Chemical research in toxicology, 2011, Aug-15, Volume: 24, Issue:8

    Topics: Acetylcysteine; Amino Acid Sequence; Arginine; Creatine Kinase; Lysine; Models, Molecular; Peptides; Phloretin; Phlorhizin; Protein Binding; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization

2011
Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.
    Clinical journal of the American Society of Nephrology : CJASN, 2011, Volume: 6, Issue:10

    Topics: Acetylcysteine; Aged; Aged, 80 and over; Arginine; Belgium; Biomarkers; Case-Control Studies; Cell Line; Chronic Disease; Cross-Sectional Studies; Female; Humans; Inflammation Mediators; Interleukin-6; Kidney Diseases; Linear Models; Male; Middle Aged; Monocytes; NF-kappa B; Predictive Value of Tests; ROC Curve; Tumor Necrosis Factor-alpha

2011
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice.
    Molecular vision, 2011, Volume: 17

    Topics: Acetylcysteine; Administration, Topical; Aging; Animals; Arginine; Ascorbic Acid; Biological Transport, Active; Cataract; Crystallins; Gene Knock-In Techniques; Glycation End Products, Advanced; Guanidines; Humans; Lens, Crystalline; Mass Spectrometry; Mice; Mice, Transgenic; Ophthalmic Solutions; Penicillamine; Rabbits; Sodium-Coupled Vitamin C Transporters; Spectrometry, Fluorescence

2011
Multidrug strategies are effective in the treatment of severe experimental pancreatitis.
    Surgery, 2012, Volume: 151, Issue:3

    Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Dextrans; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats

2012
Heme arginate potentiates latent HIV-1 reactivation while inhibiting the acute infection.
    Antiviral research, 2011, Volume: 92, Issue:3

    Topics: Acetylcysteine; Anti-HIV Agents; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Arginine; Cell Line; Heme; Heme Oxygenase-1; HIV-1; Humans; Jurkat Cells; Lectins, C-Type; Metalloporphyrins; Protoporphyrins; Proviruses; Reverse Transcription; Virus Activation; Virus Latency; Virus Replication

2011
Toxicity of 6-hydroxydopamine: live cell imaging of cytoplasmic redox flux.
    Cell biology and toxicology, 2012, Volume: 28, Issue:2

    Topics: Acetylcysteine; Arginine; Cell Culture Techniques; Cell Death; Cell Line, Tumor; Cell Survival; Cloning, Molecular; Culture Media; Cytoplasm; Glucose; Green Fluorescent Proteins; HEK293 Cells; Humans; Molecular Imaging; Mutation; Neurons; Oxidation-Reduction; Oxidative Stress; Oxidopamine; Phenylalanine; Toxicity Tests; Transfection

2012
Effect of advanced glycation end products on oxidative stress and senescence of trabecular meshwork cells.
    Korean journal of ophthalmology : KJO, 2012, Volume: 26, Issue:2

    Topics: Acetylcysteine; Apoptosis; Arginine; Cell Survival; Cells, Cultured; Cellular Senescence; Glycation End Products, Advanced; Humans; Nitric Oxide; Oxidative Stress; Pterins; Reactive Oxygen Species; Serum Albumin, Bovine; Trabecular Meshwork

2012
Proteinuria elevates asymmetric dimethylarginine levels via protein arginine methyltransferase-1 overexpression in a rat model of nephrotic syndrome.
    Life sciences, 2012, Sep-24, Volume: 91, Issue:9-10

    Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Cells, Cultured; Disease Models, Animal; Doxorubicin; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Kidney Tubules, Proximal; Male; Nephrotic Syndrome; Oxidative Stress; Protein-Arginine N-Methyltransferases; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin; Time Factors

2012
Lesson from acute experimental pancreatitis: multidrug strategies is effective than single-target therapy.
    JOP : Journal of the pancreas, 2012, Sep-10, Volume: 13, Issue:5

    Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Gabexate; Humans; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreas; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats; Survival Analysis; Survival Rate; Treatment Outcome

2012
Asymmetric dimethylarginine accumulates in the kidney during ischemia/reperfusion injury.
    Kidney international, 2014, Volume: 85, Issue:3

    Topics: Acetylcysteine; Amidohydrolases; Animals; Arginine; Kidney; Male; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Oxidative Stress; Reperfusion Injury

2014
Ischaemia-reperfusion injury: a major protagonist in kidney transplantation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014, Volume: 29, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Cold Ischemia; Complement C5a; Delayed Graft Function; Dendritic Cells; Graft Survival; Humans; Immunity, Innate; Inflammation; Kidney; Kidney Transplantation; Male; Reperfusion Injury; Tissue Donors; Toll-Like Receptors; Warm Ischemia

2014
N-acetylcysteine prevents hypertension via regulation of the ADMA-DDAH pathway in young spontaneously hypertensive rats.
    BioMed research international, 2013, Volume: 2013

    Topics: Acetylcysteine; Amidohydrolases; Animals; Arginine; Blood Pressure; Glutathione; Humans; Hypertension; Metabolic Networks and Pathways; Nitric Oxide; Oxidative Stress; Rats; Superoxides

2013
Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation.
    The Journal of biological chemistry, 2014, May-23, Volume: 289, Issue:21

    Topics: Acetylcysteine; Animals; Arginine; Benzhydryl Compounds; Blotting, Western; Cells, Cultured; Complement Activation; Complement Factor B; Complement Pathway, Alternative; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Free Radical Scavengers; Heat-Shock Proteins; Humans; Lipid Metabolism; Lipids; Macular Degeneration; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotiana; Nicotine; Oxidative Stress; Receptors, Complement; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; Smoke; Transcription Factor CHOP

2014
The role of nitric oxide synthase signaling pathway in the Zn-induced cellular responses in MCF-7 cells.
    Environmental toxicology and pharmacology, 2014, Volume: 38, Issue:3

    Topics: Acetylcysteine; Apoptosis; Arginine; Calcium; Cell Proliferation; Chlorides; Female; Humans; MCF-7 Cells; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Transcription Factors; Zinc Compounds

2014
The role of NOS-mediated ROS accumulation in an early phase Cu-induced acute cytotoxicity in MCF-7 cells.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2015, Volume: 28, Issue:1

    Topics: Acetylcysteine; Apoptosis; Arginine; Cell Line, Tumor; Copper; Eukaryotic Initiation Factor-2; Humans; MCF-7 Cells; Nitric Oxide Synthase; Phosphorylation; Reactive Oxygen Species

2015
The cytotoxic effect of the NOS-mediated oxidative stress in MCF-7 cells after PbCl₂ exposure.
    Environmental toxicology, 2016, Volume: 31, Issue:5

    Topics: Acetylcysteine; Arginine; Cell Survival; Environmental Pollutants; Eukaryotic Initiation Factor-2; Humans; Lead; MCF-7 Cells; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2016
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.
    The Journal of biological chemistry, 2015, Jan-16, Volume: 290, Issue:3

    Topics: Acetylcysteine; Albumins; Apoptosis; Arginine; Aspartate Aminotransferases; Catalysis; Cell Survival; Cysteine; Escherichia coli; Fructose-Bisphosphate Aldolase; Glucose; Glycolates; Glyoxal; Humans; Intracellular Signaling Peptides and Proteins; Lactates; Lysine; Mass Spectrometry; Oncogene Proteins; Oxidative Stress; Parkinsonian Disorders; Protein Deglycase DJ-1; Pyruvaldehyde

2015
Asymmetrical dimethylarginine promotes the senescence of human skin fibroblasts via the activation of a reactive oxygen species-p38 MAPK-microRNA-138 pathway.
    Journal of dermatological science, 2015, Volume: 78, Issue:2

    Topics: Acetylcysteine; Arginine; Back; Cells, Cultured; Cellular Senescence; Child; Enzyme Inhibitors; Face; Fibroblasts; Free Radical Scavengers; Humans; Imidazoles; MAP Kinase Signaling System; MicroRNAs; Middle Aged; Pyridines; Reactive Oxygen Species; Skin; Skin Aging; Ultraviolet Rays

2015
Effects of N-acetylcysteine and L-arginine in the antioxidant system of C2C12 cells.
    The Journal of sports medicine and physical fitness, 2015, Volume: 55, Issue:6

    Topics: Acetylcysteine; Arginine; Cell Line; Cytochromes c; Dietary Supplements; Free Radical Scavengers; Humans; Muscle Cells

2015
Myeloid-derived suppressor cells inhibit T cell proliferation in human extranodal NK/T cell lymphoma: a novel prognostic indicator.
    Cancer immunology, immunotherapy : CII, 2015, Volume: 64, Issue:12

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Arginine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cytokines; Enzyme Inhibitors; Female; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Humans; Lymphocyte Activation; Lymphoma, Extranodal NK-T-Cell; Male; Middle Aged; Myeloid Cells; Nitric Oxide; omega-N-Methylarginine; Reactive Oxygen Species; Young Adult

2015
N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers.
    Biology of reproduction, 2016, Volume: 95, Issue:1

    Topics: Acetylcysteine; Animals; Arginine; Blood Pressure; Female; Fetal Development; Hydrogen Sulfide; Hypertension; Kidney; Male; Nitric Oxide; Pre-Eclampsia; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Suramin

2016
Endogenous asymmetric dimethylarginine accumulation precipitates the cardiac and mitochondrial dysfunctions in type 1 diabetic rats.
    European journal of pharmacology, 2021, Jul-05, Volume: 902

    Topics: Acetylcysteine; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Free Radical Scavengers; Glycosylation; Heart Diseases; Insulin Resistance; Male; Mitochondria; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Papillary Muscles; Rats, Sprague-Dawley; Signal Transduction; Streptozocin

2021