acetylcysteine and angiotensin ii

acetylcysteine has been researched along with angiotensin ii in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (16.67)	18.2507
2000's	25 (46.30)	29.6817
2010's	17 (31.48)	24.3611
2020's	3 (5.56)	2.80

Authors

Authors	Studies
Earp, HS; Huckle, WR	1
Avantaggiati, ML; Balsano, C; Burgio, VL; Chirillo, P; Collepardo, D; Levrero, M; Natoli, G; Puri, PL	1
Aldershvile, J; Boesgaard, S; Christensen, S; Dige-Petersen, H; Giese, J; Poulsen, HE	1
Berti, F; Chiesara, E; Michael, M; Oriani, G; Radice, S; Rossoni, G	1
Bokkala, S; Joseph, SK	1
Craven, PA; DeRubertis, FR; Studer, RK	1
Brecher, P; Wang, D; Yu, X	1
de Champlain, J; Wu, L	1
Delafontaine, P; Du, J; Peng, T; Scheidegger, KJ	1
Brecher, P; Cohen, RA; Wang, D; Yu, X	1
Domoto, K; Ishikawa, Y; Kawasaki, S; Okuda, M; Taguchi, M; Takahashi, A; Takahashi, T; Taniguchi, T; Yokoyama, M	1
Eguchi, S; Frank, GD; Inagami, T; Motley, ED	1
Egan, BM; Greene, EL; Lu, G; Zhang, D	1
Funakoshi, Y; Ichiki, T; Iino, N; Ito, K; Takeda, K; Takeshita, A; Tokunou, T	1
Benedict, CR; Katagiri, T; Pakala, R; Watanabe, T	1
Kirima, K; Kyaw, M; Tamaki, T; Tsuchiya, K; Yoshizumi, M	1
Griendling, KK; Rocic, P; Seshiah, P	1
Amano, S; Choei, H; Inagaki, Y; Inoue, H; Kikuchi, S; Okamoto, T; Sasaki, N; Takeuchi, M; Yamagishi, S	1
Amano, S; Inagaki, Y; Okamoto, T; Yamagishi, S	1
Fujimiya, T; Naito, K; Shiraishi, K; Yoshida, K	1
Chan, P; Chen, JJ; Chen, YL; Cheng, CF; Cheng, TH; Huang, MT; Lin, H; Liu, JC; Shih, NL	1
Ali, N; Fujita, Y; Ishizawa, K; Izawa, Y; Kanematsu, Y; Kyaw, M; Tamaki, T; Tsuchiya, K; Yamauchi, A; Yoshizumi, M	1
Fukai, N; Gochou, N; Hirata, Y; Shichiri, M; Sugiyama, T; Yoshimoto, T	1
Gao, J; Gessner, R; Köttgen, E; Niessen, H; Ohlemeyer, C; Roos, D; Wu, S	1
Crespo, MJ; Escobales, N	1
Das, DK; Das, S; Engelman, RM; Maulik, N	1
Wang, SQ; Zhang, HS	1
Bowden, GT; Chen, QM; Sun, H; Tu, VC	1
Heidland, A; Kanase, N; Lakner, U; Rutkowski, P; Schmid, U; Schupp, N; Stopper, H	1
Bao, Y; Jia, R; Yuan, J	1
Chen, P; Edwards, PA; Guo, AM; Scicli, AG; Trick, G	1
Fang, NY; Gao, PJ; Guo, SJ; Han, WQ; Shen, WL; Wu, LY; Zhang, J; Zhu, DL	1
Diwan, V; Jaggi, AS; Khanna, G; Singh, M; Singh, N	1
Chen, H; Gao, X; Liang, QS; Luo, JL; Wang, ZH; Yang, GT; Yang, L; Zou, XJ	1
Maeda, S; Matsui, T; Nishino, Y; Takeuchi, M; Yamagishi, S	1
Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, B	1
Anand-Srivastava, MB; Li, Y; Sandoval, YH	1
Jiao, S; Wang, L; Yang, X; Zhang, J; Zheng, X	1
Sun, HX; Yu, DJ; Yu, M; Zheng, Y	1
Goto, S; Hirose, Y; Miyazaki, H; Nishijima, F; Niwa, T; Shimizu, H; Zghonda, N; Zrelli, H	1
Feng, L; Liu, J; Pang, X; Wang, S; Wu, D; Zhang, X; Zhao, J	1
Dopona, EP; Furukawa, LN; Heimann, JC; Katayama, IA; Oliveira, IB; Pereira, RC; Shimizu, MH	1
Cai, Y; Wang, Y; Xu, J; Xu, Y; Zuo, X	1
Chen, L; Ding, J; Goltzman, D; Miao, D; Xiao, M; Zhang, L; Zhang, W	1
Bai, D; Gao, Y; Ge, L; Lu, X; Wang, H; Yang, G	1
Dasgupta, C; Huang, X; Li, Y; Wang, L; Xiao, D; Zhang, L	1
Belhomme, M; Buzzacott, P; Guerrero, F; Lambrechts, K; Mazur, A; Theron, M; Wang, Q	1
Gan, XX; Lu, LM; Miao, NJ; Shen, Y; Xu, D; Xu, JL; Xue, H; Zhang, W; Zhou, L	1
Jiao, X; Li, Y; Liang, M; Shu, Y; Tang, B; Wang, X; Xie, X	1
Cheng, Z; Feng, X; Gao, E; Hu, J; Lin, J; Sun, D; Wang, H; Wang, S; Wang, T; Zhang, M	1
Cha, SK; Chung, CH; Kang, JS; Kim, JH; Lee, ES; Lee, EY; Lee, JH; Lee, SJ; Son, SS	1
Chen, AD; Chen, Q; Kang, YM; Li, YH; Qiu, Y; Wang, JJ; Ye, C; Zheng, F; Zhu, GQ	1
Jorge-Aarón, RM; Rosa-Ester, MP	1
Deng, KQ; Hu, F; Ji, YX; Li, H; Liu, X; Montezano, AC; Ouyang, S; She, ZG; Tian, S; Touyz, RM; Zhang, C; Zhang, P; Zhang, XJ; Zhao, CL; Zhao, GJ; Zhu, L; Zhu, XY	1

Trials

1 trial(s) available for acetylcysteine and angiotensin ii

Article	Year
N-acetylcysteine inhibits angiotensin converting enzyme in vivo. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3 Topics: Acetylcysteine; Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Drug Interactions; Female; Heart Rate; Humans; Isosorbide Dinitrate; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin	1993

Article

Year

N-acetylcysteine inhibits angiotensin converting enzyme in vivo.

The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3

Topics: Acetylcysteine; Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Drug Interactions; Female; Heart Rate; Humans; Isosorbide Dinitrate; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin

1993

Other Studies

53 other study(ies) available for acetylcysteine and angiotensin ii

Article	Year
Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols. Biochemistry, 1994, Feb-15, Volume: 33, Issue:6 Topics: Acetylcysteine; Angiotensin II; Animals; Calcimycin; Cell Line; Cell Line, Transformed; Drug Synergism; Egtazic Acid; Enzyme Activation; Flavonoids; Flavonols; Indomethacin; Liver; Masoprocol; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quercetin; Rats; Tyrosine; Vanadates	1994
Reactive oxygen intermediates mediate angiotensin II-induced c-Jun.c-Fos heterodimer DNA binding activity and proliferative hypertrophic responses in myogenic cells. The Journal of biological chemistry, 1995, Sep-22, Volume: 270, Issue:38 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcysteine; Angiotensin II; Animals; Base Sequence; Cell Differentiation; Cell Division; DNA; DNA-Binding Proteins; Gene Expression; Isoquinolines; Mice; Molecular Sequence Data; Muscles; Oligodeoxyribonucleotides; Piperazines; Protein Biosynthesis; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Transcription Factor AP-1	1995
Hyperbaric oxygen worsens myocardial low flow ischemia-reperfusion injury in isolated rat heart. European journal of pharmacology, 1997, Feb-05, Volume: 320, Issue:1 Topics: Acetylcysteine; Angiotensin II; Animals; Coronary Circulation; Free Radical Scavengers; Heart; Hyperbaric Oxygenation; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Polydeoxyribonucleotides; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstrictor Agents; Ventricular Pressure	1997
Angiotensin II-induced down-regulation of inositol trisphosphate receptors in WB rat liver epithelial cells. Evidence for involvement of the proteasome pathway. The Journal of biological chemistry, 1997, May-09, Volume: 272, Issue:19 Topics: Acetylcysteine; Angiotensin II; Animals; Calcium Channels; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Liver; Multienzyme Complexes; Proteasome Endopeptidase Complex; Rats; Receptors, Cytoplasmic and Nuclear; Ubiquitins	1997
Antioxidant inhibition of protein kinase C-signaled increases in transforming growth factor-beta in mesangial cells. Metabolism: clinical and experimental, 1997, Volume: 46, Issue:8 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcysteine; Angiotensin II; Animals; Antioxidants; Cells, Cultured; Enzyme Activation; Female; Glucose; Kidney Glomerulus; Phorbol 12,13-Dibutyrate; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rats; Rats, Sprague-Dawley; Taurine; Thromboxane A2; Thromboxanes; Transforming Growth Factor beta; Vitamin E	1997
Nitric oxide and N-acetylcysteine inhibit the activation of mitogen-activated protein kinases by angiotensin II in rat cardiac fibroblasts. The Journal of biological chemistry, 1998, Dec-04, Volume: 273, Issue:49 Topics: Acetylcysteine; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Fibroblasts; Glutathione; Heart; Myocardium; Nitric Oxide; Phosphorylation; Protein Kinase C; Rats	1998
Superoxide anion-induced formation of inositol phosphates involves tyrosine kinase activation in smooth muscle cells from rat mesenteric artery. Biochemical and biophysical research communications, 1999, Jun-07, Volume: 259, Issue:2 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Genistein; Inositol Phosphates; Isoenzymes; Mesenteric Arteries; Muscle, Smooth, Vascular; Phospholipase C gamma; Protein Biosynthesis; Protein-Tyrosine Kinases; Rats; Signal Transduction; Superoxides; Thioctic Acid; Type C Phospholipases; Tyrphostins	1999
Angiotensin II activation of insulin-like growth factor 1 receptor transcription is mediated by a tyrosine kinase-dependent redox-sensitive mechanism. Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:9 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Calcium; Cells, Cultured; Genes, Reporter; Hydrogen Peroxide; Linoleic Acids; Muscle, Smooth, Vascular; Oxidation-Reduction; Protein-Tyrosine Kinases; Pyrrolidines; Rats; Receptor, IGF Type 1; Thiocarbamates; Transcription, Genetic	1999
Distinct effects of N-acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca(2+) levels. The Journal of biological chemistry, 2000, Apr-21, Volume: 275, Issue:16 Topics: Acetylcysteine; Angiotensin II; Animals; Calcium; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Heart; Inositol 1,4,5-Trisphosphate; Myocardium; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Penicillamine; Phosphorylation; Rats; Transcriptional Activation	2000
Participation of reactive oxygen intermediates in the angiotensin II-activated signaling pathways in vascular smooth muscle cells. Annals of the New York Academy of Sciences, 2000, Volume: 902 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Carbazoles; Carvedilol; Cells, Cultured; Epidermal Growth Factor; Hydrogen Peroxide; Muscle, Smooth, Vascular; Propanolamines; Rats; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate	2000
N-acetylcysteine inhibits angiotensin ii-mediated activation of extracellular signal-regulated kinase and epidermal growth factor receptor. Biochemical and biophysical research communications, 2001, Feb-02, Volume: 280, Issue:4 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Blotting, Western; Calcimycin; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Hydrogen Peroxide; Immunoblotting; Ionophores; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth; Phosphorylation; Precipitin Tests; Pyrimidines; Quinazolines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors; Transcriptional Activation; Tyrphostins	2001
Signaling events mediating the additive effects of oleic acid and angiotensin II on vascular smooth muscle cell migration. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Topics: Acetylcysteine; Analysis of Variance; Androstadienes; Angiotensin II; Animals; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oleic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; Signal Transduction; Wortmannin	2001
Reactive oxygen species-mediated homologous downregulation of angiotensin II type 1 receptor mRNA by angiotensin II. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antioxidants; Binding, Competitive; Cells, Cultured; Down-Regulation; Enzyme Activation; Flavonoids; Gene Expression Regulation; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transfection	2001
Mildly oxidized low-density lipoprotein acts synergistically with angiotensin II in inducing vascular smooth muscle cell proliferation. Journal of hypertension, 2001, Volume: 19, Issue:6 Topics: Acetylcysteine; Aldehydes; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Cell Division; Cells, Cultured; DNA; Drug Synergism; Flavonoids; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Lysophosphatidylcholines; Muscle, Smooth, Vascular; Probucol; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Tyrphostins	2001
Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells. Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:3 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Ascorbic Acid; Cells, Cultured; Chelating Agents; Chromans; Ditiocarb; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Onium Compounds; Oxygen Consumption; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vasoconstrictor Agents	2001
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38 Topics: Acetylcysteine; Angiotensin II; Animals; Aorta; Azoles; Blotting, Western; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genes, Dominant; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Muscle, Smooth, Vascular; Okadaic Acid; Onium Compounds; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Pyridines; Rats; Reactive Oxygen Species; Serine; Threonine; Time Factors	2003
Angiotensin II-type 1 receptor interaction upregulates vascular endothelial growth factor messenger RNA levels in retinal pericytes through intracellular reactive oxygen species generation. Drugs under experimental and clinical research, 2003, Volume: 29, Issue:2 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Cattle; Cells, Cultured; Intercellular Signaling Peptides and Proteins; Pericytes; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Vascular Endothelial Growth Factor A	2003
Angiotensin II stimulates platelet-derived growth factor-B gene expression in cultured retinal pericytes through intracellular reactive oxygen species generation. International journal of tissue reactions, 2003, Volume: 25, Issue:2 Topics: Acetylcysteine; Amino Acid Sequence; Angiotensin II; Animals; Base Sequence; Benzimidazoles; Benzoates; Cattle; Cells, Cultured; Cloning, Molecular; Gene Expression Regulation; Humans; Molecular Sequence Data; Pericytes; Proto-Oncogene Proteins c-sis; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sheep; Telmisartan; Transcriptional Activation	2003
Angiotensin II dependent testicular fibrosis and effects on spermatogenesis after vasectomy in the rat. The Journal of urology, 2003, Volume: 170, Issue:5 Topics: Acetylcysteine; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Enalapril; Fibrosis; Heat-Shock Proteins; HSP47 Heat-Shock Proteins; Leydig Cells; Losartan; Male; Rats; Rats, Wistar; Spermatogenesis; Testis; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vasectomy	2003
Inhibitory effect of resveratrol on angiotensin II-induced cardiomyocyte hypertrophy. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:2 Topics: Acetylcysteine; Angiotensin II; Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Hypertrophy; Leucine; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Cardiac; Myosin Heavy Chains; Phosphorylation; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Transfection; Ventricular Myosins	2004
Antioxidant effects of stereoisomers of N-acetylcysteine (NAC), L-NAC and D-NAC, on angiotensin II-stimulated MAP kinase activation and vascular smooth muscle cell proliferation. Journal of pharmacological sciences, 2004, Volume: 95, Issue:4 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Cell Proliferation; Enzyme Activation; Glutathione; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Stereoisomerism; Thymidine	2004
Adrenomedullin inhibits angiotensin II-induced oxidative stress and gene expression in rat endothelial cells. Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:2 Topics: Acetylcysteine; Adrenomedullin; Angiotensin II; Animals; Antioxidants; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress; Peptides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation; Vasodilator Agents	2005
Activation of AP-1 through reactive oxygen species by angiotensin II in rat cardiomyocytes. Free radical biology & medicine, 2005, Dec-15, Volume: 39, Issue:12 Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Dose-Response Relationship, Drug; Heart Ventricles; HL-60 Cells; Humans; Myocytes, Cardiac; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Transcription Factor AP-1	2005
Angiotensin II-dependent vascular alterations in young cardiomyopathic hamsters: role for oxidative stress. Vascular pharmacology, 2006, Volume: 44, Issue:1 Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aorta; Blood Pressure; Cardiomyopathies; Cricetinae; Disease Models, Animal; Losartan; Male; Mesocricetus; NADPH Oxidases; Oxidative Stress; Superoxides	2006
Angiotensin preconditioning of the heart: evidence for redox signaling. Cell biochemistry and biophysics, 2006, Volume: 44, Issue:1 Topics: Acetophenones; Acetylcysteine; Angiotensin II; Animals; Antioxidants; Apoptosis; Gene Expression; Heart; Heart Rate; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Membrane Glycoproteins; Membrane Transport Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidation-Reduction; Perfusion; Phosphoproteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling	2006
Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor-alpha (TNF-alpha)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species. Journal of molecular and cellular cardiology, 2006, Volume: 41, Issue:1 Topics: Acetophenones; Acetylcysteine; Angiotensin II; Aorta; Benzofurans; Cells, Cultured; Humans; Hydrogen Peroxide; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; NADPH Oxidases; Onium Compounds; Reactive Oxygen Species; Salvia miltiorrhiza; Tumor Necrosis Factor-alpha; Up-Regulation	2006
Involvement of oxidants and AP-1 in angiotensin II-activated NFAT3 transcription factor. American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:4 Topics: Acetylcysteine; Angiotensin II; Animals; Animals, Newborn; Antioxidants; Catalase; Cell Enlargement; Cells, Cultured; Cyclic N-Oxides; Enzyme Activation; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NFATC Transcription Factors; Oxidants; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Signal Transduction; Thioctic Acid; Transcription Factor AP-1	2007
Angiotensin II-induced genomic damage in renal cells can be prevented by angiotensin II type 1 receptor blockage or radical scavenging. American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:5 Topics: Acetylcysteine; alpha-Tocopherol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Line; Cell Nucleus; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Flow Cytometry; Free Radical Scavengers; Humans; Imidazoles; Kidney; Pyridines; Rats; Reactive Oxygen Species; Swine; Tetrazoles	2007
Aldosterone up-regulates production of plasminogen activator inhibitor-1 by renal mesangial cells. Journal of biochemistry and molecular biology, 2007, Mar-31, Volume: 40, Issue:2 Topics: Acetylcysteine; Aldosterone; Angiotensin II; Animals; Antibodies; Cells, Cultured; Dose-Response Relationship, Drug; Mesangial Cells; Neutralization Tests; Plasminogen Activator Inhibitor 1; Rats; Reactive Oxygen Species; RNA, Messenger; Spironolactone; Time Factors; Transforming Growth Factor beta1; Up-Regulation	2007
Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis. American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:4 Topics: Acetophenones; Acetylcysteine; Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Imidazoles; Indoles; Leukostasis; Losartan; Male; NADPH Oxidases; Pyridines; Pyrroles; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retinal Diseases; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents	2007
Peroxisome proliferator-activated receptor-gamma agonists attenuate angiotensin II-induced collagen type I expression in adventitial fibroblasts. Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:1 Topics: Acetylcysteine; Angiotensin II; Animals; Cells, Cultured; Collagen Type I; Connective Tissue; Dose-Response Relationship, Drug; Fibroblasts; Free Radical Scavengers; Male; NF-kappa B; Oxidative Stress; Pioglitazone; PPAR gamma; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Thiazolidinediones; Time Factors; Transcription Factor AP-1	2008
Reduction of ischemic, pharmacological and remote preconditioning effects by an antioxidant N-acetyl cysteine pretreatment in isolated rat heart. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:3 Topics: Acetylcysteine; Angiotensin II; Animals; Cardiotonic Agents; Female; Free Radical Scavengers; Hydrogen Peroxide; In Vitro Techniques; Ischemic Preconditioning; Male; Myocardial Infarction; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species	2008
Sodium tanshinone IIA sulfonate attenuates angiotensin II-induced collagen type I expression in cardiac fibroblasts in vitro. Experimental & molecular medicine, 2009, Jul-31, Volume: 41, Issue:7 Topics: Acetylcysteine; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Collagen Type I; Drugs, Chinese Herbal; Fibroblasts; Free Radical Scavengers; In Vitro Techniques; Matrix Metalloproteinase 1; Myocardium; NADPH Oxidases; Oxidative Stress; Phenanthrenes; Rats; Rats, Wistar; Reactive Oxygen Species	2009
Irbesartan inhibits advanced glycation end product (AGE)-induced up-regulation of vascular cell adhesion molecule-1 (VCAM-1) mRNA levels in glomerular endothelial cells. Microvascular research, 2011, Volume: 81, Issue:3 Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Biphenyl Compounds; Cells, Cultured; Endothelial Cells; Gene Expression; Glycation End Products, Advanced; Humans; Hydrogen Peroxide; Irbesartan; Kidney Glomerulus; Peptidyl-Dipeptidase A; Renin; Salicylates; Serum Albumin, Bovine; Superoxides; Tetrazoles; Up-Regulation; Vascular Cell Adhesion Molecule-1	2011
Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 27, Issue:1 Topics: Acetylcysteine; Angiotensin II; Antihypertensive Agents; C-Reactive Protein; Flavonoids; Humans; Imidazoles; Losartan; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Pyridines; Thiocarbamates; U937 Cells	2011
Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR. Cellular signalling, 2011, Volume: 23, Issue:11 Topics: Acetylcysteine; Adenylyl Cyclases; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Colforsin; CSK Tyrosine-Protein Kinase; ErbB Receptors; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypertension; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; src-Family Kinases; Transcriptional Activation	2011
Losartan inhibits STAT1 activation and protects human glomerular mesangial cells from angiotensin II induced premature senescence. Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:1 Topics: Acetylcysteine; Angiotensin II; beta-Galactosidase; Cell Cycle Checkpoints; Cell Line; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Gene Knockdown Techniques; Humans; Losartan; Mesangial Cells; Reactive Oxygen Species; Signal Transduction; STAT1 Transcription Factor; Tumor Suppressor Protein p53	2012
Inhibitory effects of enalaprilat on rat cardiac fibroblast proliferation via ROS/P38MAPK/TGF-β1 signaling pathway. Molecules (Basel, Switzerland), 2012, Mar-06, Volume: 17, Issue:3 Topics: Acetylcysteine; Active Transport, Cell Nucleus; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Enalaprilat; Fibroblasts; Gene Expression; Imidazoles; MAP Kinase Signaling System; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Plant Extracts; Pyridines; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Transforming Growth Factor beta1	2012
Indoxyl sulfate enhances angiotensin II signaling through upregulation of epidermal growth factor receptor expression in vascular smooth muscle cells. Life sciences, 2012, Sep-04, Volume: 91, Issue:5-6 Topics: Acetylcysteine; Angiotensin II; Animals; Arteriosclerosis; Cells, Cultured; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Indican; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tyrphostins; Up-Regulation	2012
Angiotensin II induces C-reactive protein expression via AT1-ROS-MAPK-NF-κB signal pathway in hepatocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 32, Issue:3 Topics: Acetylcysteine; Angiotensin II; Animals; C-Reactive Protein; Cell Line; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Recombinant Proteins; RNA, Messenger; Signal Transduction; Thenoyltrifluoroacetone	2013
High-salt intake induces cardiomyocyte hypertrophy in rats in response to local angiotensin II type 1 receptor activation. The Journal of nutrition, 2014, Volume: 144, Issue:10 Topics: Acetylcysteine; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Hematocrit; Hydralazine; Losartan; Male; Myocytes, Cardiac; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Thiobarbituric Acid Reactive Substances	2014
Down-regulation of ether-a-go-go-related gene potassium channel protein through sustained stimulation of AT1 receptor by angiotensin II. Biochemical and biophysical research communications, 2014, Sep-26, Volume: 452, Issue:3 Topics: Acetylcysteine; Angiotensin II; Brefeldin A; Endoplasmic Reticulum; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression Regulation; Golgi Apparatus; HEK293 Cells; Humans; Indoles; Lysosomes; Macrolides; Maleimides; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Stability; Protein Transport; Proteolysis; Receptor, Angiotensin, Type 1; Signal Transduction; Transfection	2014
Administration of exogenous 1,25(OH)2D3 normalizes overactivation of the central renin-angiotensin system in 1α(OH)ase knockout mice. Neuroscience letters, 2015, Feb-19, Volume: 588 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Blood Pressure; Brain; Calcitriol; Calcium; Diet; Mice, Knockout; Oxidative Stress; Phosphorus; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Steroid Hydroxylases; Vitamins	2015
Cytoplasmic translocation of HuR contributes to angiotensin II induced cardiac fibrosis. Biochemical and biophysical research communications, 2015, Aug-07, Volume: 463, Issue:4 Topics: Acetylcysteine; Angiotensin II; Animals; Collagen; Cytoplasm; Dose-Response Relationship, Drug; ELAV Proteins; Heart Diseases; Male; Mice; Mice, Inbred C57BL; Protein Transport; Reactive Oxygen Species; Transforming Growth Factor beta	2015
Antenatal Antioxidant Prevents Nicotine-Mediated Hypertensive Response in Rat Adult Offspring. Biology of reproduction, 2015, Volume: 93, Issue:3 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Body Weight; Enzyme Activation; Female; Humans; Hypertension; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotine; Nicotinic Agonists; Phorbol 12,13-Dibutyrate; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species	2015
Antioxidants, endothelial dysfunction, and DCS: in vitro and in vivo study. Journal of applied physiology (Bethesda, Md. : 1985), 2015, Dec-15, Volume: 119, Issue:12 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Ascorbic Acid; Cell Death; Cell Survival; Cells, Cultured; Decompression Sickness; Diving; Endothelium, Vascular; Glutathione; Male; Nitric Oxide; Oxidative Stress; Peptidyl-Dipeptidase A; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Superoxides; Thiobarbituric Acid Reactive Substances	2015
N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys. Acta pharmacologica Sinica, 2016, Volume: 37, Issue:5 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Cell Line; Fibroblasts; Fibrosis; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Ureteral Obstruction	2016
A Two-Photon H Angewandte Chemie (International ed. in English), 2018, 09-17, Volume: 57, Issue:38 Topics: Acetylcysteine; Angiotensin II; Animals; Borates; Carbon Monoxide; Flavonoids; Fluorescent Dyes; Hydrogen Peroxide; Lasers; Muscle, Smooth, Vascular; Photolysis; Photons; Spectrometry, Fluorescence; Zebrafish	2018
Cardiac-specific Mst1 deficiency inhibits ROS-mediated JNK signalling to alleviate Ang II-induced cardiomyocyte apoptosis. Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:1 Topics: Acetylcysteine; Angiotensin II; Animals; Apoptosis; Cardiomyopathies; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Signal Transduction; Thioredoxins	2019
Angiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease. Scientific reports, 2019, 05-22, Volume: 9, Issue:1 Topics: Acetylcysteine; Actin Cytoskeleton; Angiotensin II; Animals; Calcium; Cell Adhesion; Cell Line, Transformed; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Down-Regulation; Humans; Losartan; Mice; Mice, Inbred C57BL; Microfilament Proteins; Molecular Motor Proteins; Myosin Heavy Chains; NADPH Oxidase 4; Podocytes; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Receptors, Leptin; RNA Interference; TRPC6 Cation Channel	2019
Angiotensin Type 1 Receptors and Superoxide Anion Production in Hypothalamic Paraventricular Nucleus Contribute to Capsaicin-Induced Excitatory Renal Reflex and Sympathetic Activation. Neuroscience bulletin, 2020, Volume: 36, Issue:5 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Acetylcysteine; Allopurinol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Capsaicin; Captopril; Ditiocarb; Kidney; Losartan; Male; NADPH Oxidases; Onium Compounds; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Superoxides	2020
N-acetylcysteine as a potential treatment for COVID-19. Future microbiology, 2020, Volume: 15 Topics: Acetylcysteine; Angiotensin II; Antioxidants; Betacoronavirus; Coronavirus Infections; COVID-19; Cytokines; Humans; Oxidative Stress; Pandemics; Pneumonia, Viral; SARS-CoV-2; Virus Internalization	2020
Ca Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:3 Topics: Acetylcysteine; Angiotensin II; Animals; Cardiomegaly; Free Radical Scavengers; Gene Expression Regulation; Humans; Isoenzymes; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; NADPH Oxidase 5; Oxidative Stress; Phagocytes; Rats; Reactive Oxygen Species; Signal Transduction; Vasoconstrictor Agents; Ventricular Myosins	2020