acetylcysteine has been researched along with amyloid beta-peptides in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ancolio, K; Checler, F; Lopez-Perez, E; Marambaud, P | 1 |
| Alkon, DL; Favit, A; Grimaldi, M; Nelson, TJ | 1 |
| Alkon, DL; Favit, A; Grimaldi, M | 1 |
| Baysang, G; Brack, C; Brockhaus, M; Meier, F; Müller-Spahn, F; Olivieri, G; Stähelin, HB | 1 |
| Brera, B; de Ceballos, ML; Fernández-Tomé, MP | 1 |
| Bardini, P; Danni, O; Guglielmotto, M; Marra, L; Parola, M; Santoro, G; Tabaton, M; Tamagno, E | 1 |
| Qing, H; Song, W; Tong, Y; Zhou, W | 1 |
| Moir, RD; Myre, MA; Tanzi, RE; Tesco, G; Wasco, W; Washicosky, K | 1 |
| Chan, WH; Choi, MM; Li, HW; Xiao, L; Zhao, D | 1 |
| Chen, SH; Gean, PW; Hsiao, YH; Kuo, JR | 1 |
| Arimon, M; Berezovska, O; Hyman, BT; Post, KL; Svirsky, S; Takeda, S | 1 |
11 other study(ies) available for acetylcysteine and amyloid beta-peptides
| Article | Year |
|---|---|
Proteasome inhibitors prevent the degradation of familial Alzheimer's disease-linked presenilin 1 and potentiate A beta 42 recovery from human cells.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Kidney; Membrane Proteins; Multienzyme Complexes; Oligopeptides; Peptide Fragments; Presenilin-1; Proteasome Endopeptidase Complex; Ubiquitins | 1998 |
Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Brain; Cells, Cultured; Cycloheximide; Fibroblasts; Humans; Isoenzymes; Peptide Fragments; Protein Kinase C; Protein Kinase C-alpha; Protein Synthesis Inhibitors; Rats; Tetradecanoylphorbol Acetate | 1998 |
Prevention of beta-amyloid neurotoxicity by blockade of the ubiquitin-proteasome proteolytic pathway.
Topics: Acetylcysteine; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Fetus; Multienzyme Complexes; Neurons; Neurotoxins; Peptide Fragments; Proteasome Endopeptidase Complex; Ubiquitins | 2000 |
N-acetyl-L-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: effects on beta-amyloid secretion and tau phosphorylation.
Topics: Acetylcysteine; Amyloid beta-Peptides; Blotting, Western; Cell Survival; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutathione; Glutathione Reductase; Humans; Hydrogen Peroxide; Neuroblastoma; Oxidative Stress; Peptide Fragments; Phosphorylation; tau Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Ultraviolet Rays | 2001 |
beta-Amyloid-induced cytotoxicity, peroxide generation and blockade of glutamate uptake in cultured astrocytes.
Topics: Acetylcysteine; Amyloid beta-Peptides; Astrocytes; Catalase; Cell Survival; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Free Radicals; Glutamic Acid; Humans; Neurons; Peptide Fragments; Peroxides; Time Factors; Vitamin E | 2001 |
Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis.
Topics: Acetylcysteine; alpha-Tocopherol; Amyloid beta-Peptides; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Caspase 3; Caspases; Cell Differentiation; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neuroblastoma; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
BACE1 gene expression and protein degradation.
Topics: Acetylcysteine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Aspartic Acid Endopeptidases; Cell Line, Tumor; Cloning, Molecular; Cysteine Proteinase Inhibitors; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Isoquinolines; Mutagenesis; Peptide Fragments; Peptide Hydrolases; Phosphopyruvate Hydratase; Promoter Regions, Genetic; Sp1 Transcription Factor; Time Factors; Transfection | 2004 |
Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.
Topics: Acetylcysteine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzazepines; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclin D1; Fibroblasts; Glioma; Hexanones; Humans; Hydrocarbons, Chlorinated; Indoles; Leupeptins; Mice; Peptide Fragments; Proteasome Inhibitors; Purines; Recombinant Fusion Proteins; Roscovitine; Threonine | 2009 |
Inhibition of beta 1-40 amyloid fibrillation with N-acetyl-L-cysteine capped quantum dots.
Topics: Acetylcysteine; Amyloid beta-Peptides; Benzothiazoles; Fluorescent Dyes; Kinetics; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Peptide Fragments; Quantum Dots; Thiazoles | 2010 |
Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antioxidants; Biophysics; Biotinylation; Calpain; Cell Line, Transformed; Cognition Disorders; Conditioning, Psychological; Cyclin-Dependent Kinase 5; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Fear; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Patch-Clamp Techniques; Peptide Fragments; Presenilin-1; Protein Kinase C-delta; Receptors, Metabotropic Glutamate; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Social Isolation; Time Factors; Transfection | 2012 |
Oxidative stress and lipid peroxidation are upstream of amyloid pathology.
Topics: Acetylcysteine; Aldehydes; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Brain; Disulfides; Lipid Peroxidation; Membrane Glycoproteins; Mice; Oxidative Stress; Peptide Fragments; Presenilin-1; Pyridines | 2015 |