acetylcysteine and ambroxol

acetylcysteine has been researched along with ambroxol in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.15)18.7374
1990's10 (30.30)18.2507
2000's5 (15.15)29.6817
2010's7 (21.21)24.3611
2020's6 (18.18)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Baldini, G; Gucci, M; Memmini, C; Tarò, D1
Del Donno, M; Marsico, SA; Olivieri, D1
Bender, SW; Hofmann, D; Posselt, HG; Ratjen, F; Stöver, B; Wönne, R1
Gargani, GF; Minicucci, L; Nantron, M; Romano, C1
Cadel, S; Maiorino, M; Riunno, M; Schiantarelli, P1
Alvarez-Sala, R; Caballero, P; García Río, F; Pino, JM; Prados, C; Villamor, J1
Antczak, A; Bialasiewicz, P; Krol, M; Nowak, D; Pietras, T1
Felix, K; Pairet, M; Zimmermann, R1
Bartling, A; Gillissen, A; Jaworska, M; Rasche, K; Schärling, B; Schultze-Werninghaus, G1
Bartling, A; Gillissen, A; Schoen, S; Schultze-Werninghaus, G1
Sanchis, J; Serrano, J1
Gillissen, A; Nowak, D1
Gibbs, BF; Grabbe, J; Wolff, HH1
Franová, S; Nosál'ová, G; Strapková, A1
Bialasiewicz, P; Komos, J; Nawrocka, A; Nowak, D; Papierz, W; Stolarek, R1
Aihara, M; Akiyama, M; Dobashi, K; Mori, M; Nakazawa, T; Naruse, I1
Ekberg-Jansson, A; Larsson, S; Löfdahl, CG1
Kuna, P; Kupczyk, M2
Nash, EF; Ratjen, F; Stephenson, A; Tullis, E1
Lewinski, A; Nowak, D; Pietras, T; Sewerynek, E; Stuss, M; Wiktorska, JA1
Albrecht, HH; Hill, DB; Rogers, DF; Seagrave, J; Solomon, G1
Nash, EF; Ratjen, F; Stephenson, A; Tam, J; Tullis, E1
Beller, M; Giese, AK; Gläser, A; Lukas, J; Pockrandt, AM; Pohlers, S; Rolfs, A; Runge, F; Seemann, S; Sharif, M; Zheng, C1
Icard, BL; Rubio, E1
Calzetta, L; Cazzola, M; Hanania, NA; Matera, MG; Rogliani, P1
Elgamasy, S; Ghozy, S; Islam, SMS; Kamel, MG; Khalil, A; Morra, ME1
Döring, K; Schmidtke, M; Walther, C1
Alcalde, M; Calefi, PHS; de Azevedo Queiroz, I; Duarte, MAH; Kato, AS; Oliveira, S; Vivan, RR; Weckwerth, PH1
Bian, J; Liang, H; Zhang, M1
Chen, XB; Deng, ZP; Papi, A; Qu, JM; Tang, W; Wu, F; Xu, JF; Yang, JP; Zhu, D1
Chen, C; Liu, K; Wang, Y; Zhang, C1

Reviews

8 review(s) available for acetylcysteine and ambroxol

ArticleYear
[Usefulness of mucoactive drugs in respiratory diseases].
    Archivos de bronconeumologia, 1998, Volume: 34, Issue:1

    Topics: Acetylcysteine; Ambroxol; Bromhexine; Bronchiectasis; Bronchitis; Cystic Fibrosis; Deoxyribonuclease I; Dioxanes; Expectorants; Glycerol; Humans; Lung Diseases, Obstructive; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic

1998
Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy.
    Respiratory medicine, 1998, Volume: 92, Issue:4

    Topics: Acetylcysteine; Ambroxol; Animals; Expectorants; Free Radical Scavengers; Humans; Lung; Lung Diseases

1998
[Mucolytics in acute and chronic respiratory tract disorders. I. Pathophysiology and mechanisms of action].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 12, Issue:69

    Topics: Acetylcysteine; Acute Disease; Ambroxol; Chronic Disease; Expectorants; Humans; Respiratory Tract Diseases

2002
[Mucolytics in acute and chronic respiratory tract disorders. II. Uses for treatment and antioxidant properties].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 12, Issue:69

    Topics: Acetylcysteine; Acute Disease; Ambroxol; Antioxidants; Asthma; Chronic Disease; Expectorants; Humans; Respiratory Tract Diseases

2002
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis.
    The Cochrane database of systematic reviews, 2009, Jan-21, Issue:1

    Topics: Acetylcysteine; Administration, Inhalation; Administration, Oral; Ambroxol; Carbocysteine; Cystic Fibrosis; Expectorants; Humans; Lung Diseases; Mucociliary Clearance; Randomized Controlled Trials as Topic

2009
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis.
    The Cochrane database of systematic reviews, 2013, Jul-12, Issue:7

    Topics: Acetylcysteine; Administration, Inhalation; Administration, Oral; Ambroxol; Carbocysteine; Cystic Fibrosis; Expectorants; Glutathione; Humans; Lung Diseases; Mucociliary Clearance; Nebulizers and Vaporizers; Randomized Controlled Trials as Topic; Saline Solution, Hypertonic

2013
The role of mucoactive agents in the mechanically ventilated patient: a review of the literature.
    Expert review of respiratory medicine, 2017, Volume: 11, Issue:10

    Topics: Acetylcysteine; Ambroxol; Critical Care; Critical Illness; Deoxyribonuclease I; Expectorants; Guaifenesin; Humans; Intensive Care Units; Mannitol; Mucociliary Clearance; Potassium Dichromate; Recombinant Proteins; Respiration, Artificial; Saline Solution, Hypertonic; Sodium Bicarbonate

2017
Impact of Mucolytic Agents on COPD Exacerbations: A Pair-wise and Network Meta-analysis.
    COPD, 2017, Volume: 14, Issue:5

    Topics: Acetylcysteine; Ambroxol; Carbocysteine; Disease Progression; Expectorants; Humans; Network Meta-Analysis; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Thioglycolates; Thiophenes

2017

Trials

5 trial(s) available for acetylcysteine and ambroxol

ArticleYear
[A controlled study on the action of a new formulation of ambroxol in asthmatiform bronchitis in children].
    Minerva pediatrica, 1989, Volume: 41, Issue:2

    Topics: Acetylcysteine; Adolescent; Ambroxol; Bromhexine; Bronchitis; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Lung Diseases, Obstructive; Male; Random Allocation; Time Factors

1989
Improvement of mucociliary transport in smokers by mucolytics.
    European journal of respiratory diseases. Supplement, 1985, Volume: 139

    Topics: Acetylcysteine; Adult; Ambroxol; Biological Transport; Bromhexine; Bronchitis; Cilia; Double-Blind Method; Female; Humans; Male; Middle Aged; Mucus; Random Allocation; Smoking; Trachea

1985
A double-blind placebo controlled trial with oral ambroxol and N-acetylcysteine for mucolytic treatment in cystic fibrosis.
    European journal of pediatrics, 1985, Volume: 144, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Ambroxol; Bromhexine; Child; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Expectorants; Female; Humans; Male; Mucus; Respiratory Function Tests

1985
[Controlled clinical study on the activity of a new mucoregulating drug in obstructive bronchial pathology with a marked hypersecretory feature. The pediatric experience].
    Minerva pediatrica, 1984, Feb-15, Volume: 36, Issue:3

    Topics: Acetylcysteine; Adolescent; Ambroxol; Bromhexine; Bronchial Diseases; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; Female; Humans; Male; Mucus

1984
Intravenous N-acetylcysteine in respiratory disease with abnormal mucus secretion.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:11

    Topics: Acetylcysteine; Ambroxol; Double-Blind Method; Expectorants; Humans; Mucus; Respiration Disorders

2023

Other Studies

20 other study(ies) available for acetylcysteine and ambroxol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Secretodynamic activity of ambroxol in the experimental animal: comparison with bromhexine, sobrerol, domiodol and N-acetyl-L-cysteine].
    Bollettino chimico farmaceutico, 1982, Volume: 121, Issue:9

    Topics: Acetylcysteine; Ambroxol; Animals; Bromhexine; Dioxolanes; Fluoresceins; Male; Mice; Respiratory System; Terpenes

1982
Six cases of pulmonary alveolar proteinosis: presentation of unusual associations.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1995, Volume: 50, Issue:1

    Topics: Acetylcysteine; Adult; Ambroxol; Biopsy; Brain Neoplasms; Bronchoalveolar Lavage Fluid; Child; Fanconi Syndrome; Female; Glioblastoma; Heart Septal Defects; Humans; Infant, Newborn; Lung; Male; Middle Aged; Oxygen Inhalation Therapy; Pulmonary Alveolar Proteinosis; Respiratory Function Tests; Tuberculosis, Pulmonary

1995
Protective effect of ambroxol against heat- and hydrogen peroxide-induced damage to lung lipids in mice.
    The European respiratory journal, 1994, Volume: 7, Issue:9

    Topics: Acetylcysteine; Ambroxol; Animals; Antioxidants; Heart; Hot Temperature; Hydrogen Peroxide; Lipid Peroxidation; Liver; Lung; Male; Methionine; Mice; Mice, Inbred BALB C; Pulmonary Surfactants

1994
The antioxidative activity of the mucoregulatory agents: ambroxol, bromhexine and N-acetyl-L-cysteine. A pulse radiolysis study.
    Life sciences, 1996, Volume: 59, Issue:14

    Topics: Acetylcysteine; Ambroxol; Antioxidants; Bromhexine; Expectorants; Hydroxyl Radical; Kinetics; Pulse Radiolysis; Superoxides

1996
Oxidant scavenger function of ambroxol in vitro: a comparison with N-acetylcysteine.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1997, Volume: 196, Issue:6

    Topics: Acetylcysteine; Ambroxol; Antioxidants; Expectorants; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Hydroxides; Hypochlorous Acid; In Vitro Techniques; Superoxides

1997
Antioxidant function of ambroxol in mononuclear and polymorphonuclear cells in vitro.
    Lung, 1997, Volume: 175, Issue:4

    Topics: Acetylcysteine; Adult; Ambroxol; Antioxidants; Catalase; Expectorants; Female; Free Radical Scavengers; Glutathione; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lysine; Male; Neutrophils; Reactive Oxygen Species; Superoxide Dismutase

1997
Effects of free radical scavengers on histamine release from human basophils stimulated by immunological and non-immunological secretagogues.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1999, Volume: 48 Suppl 1

    Topics: Acetylcysteine; Ambroxol; Basophils; Calcimycin; Free Radical Scavengers; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine Release; Humans; Immunoglobulin E; Interleukin-3; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Vitamin E

1999
Mucolytics and antioxidant activity.
    Life sciences, 1999, Volume: 65, Issue:18-19

    Topics: Acetylcysteine; Ambroxol; Animals; Antioxidants; Expectorants; Free Radical Scavengers; Guinea Pigs; Histamine Release; Injections, Intraperitoneal; Lung; Male; Muscle, Smooth; Respiratory Tract Diseases; Toluene; Trachea

1999
N-acetylcysteine and ambroxol inhibit endotoxin-induced phagocyte accumulation in rat lungs.
    Pulmonary pharmacology & therapeutics, 1999, Volume: 12, Issue:6

    Topics: Acetylcysteine; Ambroxol; Animals; Endotoxins; Escherichia coli; Expectorants; Humans; Lipopolysaccharides; Luminescent Measurements; Lung; Macrophages, Alveolar; Male; Neutrophils; Phagocytes; Pulmonary Alveoli; Rats; Rats, Wistar

1999
Effects of N-acetylcysteine and ambroxol on the production of IL-12 and IL-10 in human alveolar macrophages.
    Respiration; international review of thoracic diseases, 2000, Volume: 67, Issue:6

    Topics: Acetylcysteine; Adult; Ambroxol; Dose-Response Relationship, Drug; Expectorants; Female; Humans; Interleukin-10; Interleukin-12; Lipopolysaccharides; Macrophages, Alveolar; Male; Reference Values

2000
Preventing exacerbations of chronic bronchitis and COPD.
    BMJ (Clinical research ed.), 2001, May-26, Volume: 322, Issue:7297

    Topics: Acetylcysteine; Adjuvants, Immunologic; Ambroxol; Antioxidants; Bacteria; Bronchitis; Cell Extracts; Chronic Disease; Expectorants; Haemophilus influenzae; Humans; Interferon Inducers; Lung Diseases, Obstructive

2001
Effects of certain antioxidants on lipid peroxidation process in lung homogenates of L thyroxine-receiving rats.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:1

    Topics: Acetylcysteine; Ambroxol; Animals; Antioxidants; Antithyroid Agents; Drug Evaluation, Preclinical; Free Radical Scavengers; Injections, Intraperitoneal; Lipid Peroxidation; Lung; Male; Malondialdehyde; Melatonin; Propylthiouracil; Rats; Rats, Wistar; Schiff Bases; Thyroxine; Tissue Extracts; Triiodothyronine

2010
Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells.
    Respiratory research, 2012, Oct-31, Volume: 13

    Topics: Acetylcysteine; Ambroxol; Cells, Cultured; Expectorants; Guaifenesin; Humans; Interleukin-13; Mucin 5AC; Mucociliary Clearance; Respiratory Mucosa

2012
Enzyme enhancers for the treatment of Fabry and Pompe disease.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2015, Volume: 23, Issue:3

    Topics: 1-Deoxynojirimycin; Acetylcysteine; alpha-Galactosidase; alpha-Glucosidases; Ambroxol; Bezafibrate; Enzyme Activators; Fabry Disease; Gene Expression; Glycogen Storage Disease Type II; HEK293 Cells; Humans; Leupeptins; Lysosomes; Pioglitazone; Plasmids; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; Recombinant Proteins; Thiazolidinediones; Transfection

2015
First case of focal epilepsy associated with SARS-coronavirus-2.
    Journal of medical virology, 2020, Volume: 92, Issue:10

    Topics: Acetaminophen; Acetylcysteine; Aged; Ambroxol; Anticonvulsants; Cough; COVID-19; COVID-19 Drug Treatment; Dipyrone; Epilepsies, Partial; Female; Fever; Humans; Nasopharynx; Radiography, Abdominal; SARS-CoV-2; Treatment Outcome

2020
Comparative in vitro analysis of inhibition of rhinovirus and influenza virus replication by mucoactive secretolytic agents and plant extracts.
    BMC complementary medicine and therapies, 2020, Dec-23, Volume: 20, Issue:1

    Topics: Acetylcysteine; Ambroxol; Animals; Bromhexine; Dogs; HeLa Cells; Humans; Influenza A virus; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Pelargonium; Phytotherapy; Plant Extracts; Respiratory Tract Infections; Rhinovirus; Thymus Plant; Toxicity Tests; Virus Replication

2020
Comparison of the Physicochemical Properties, Antimicrobial Action, and Cytotoxicity of Ambroxol Hydrochloride, N-acetylcysteine, and Calcium Hydroxide Pastes.
    European endodontic journal, 2022, Volume: 7, Issue:3

    Topics: Acetylcysteine; Ambroxol; Anti-Infective Agents; Calcium Hydroxide; Chemical Phenomena; Enterococcus faecalis; Water

2022
Comparison of Clinical Effectiveness Between Ambroxol and N-Acetylcysteine in Surgical Patients: A Retrospective Cohort Study.
    Journal of clinical pharmacology, 2023, Volume: 63, Issue:2

    Topics: Acetylcysteine; Adolescent; Adult; Ambroxol; Expectorants; Humans; Lung; Postoperative Complications; Retrospective Studies; Treatment Outcome

2023
Acetylcysteine and budesonide for the treatment of refractory Mycoplasma pneumoniae pneumonia in children: a clinical observation.
    Italian journal of pediatrics, 2023, Jul-08, Volume: 49, Issue:1

    Topics: Acetylcysteine; Ambroxol; Budesonide; Child; Humans; Mycoplasma pneumoniae; Pneumonia, Mycoplasma; Retrospective Studies

2023