acetylcysteine has been researched along with allopurinol in 95 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (6.32) | 18.7374 |
| 1990's | 20 (21.05) | 18.2507 |
| 2000's | 39 (41.05) | 29.6817 |
| 2010's | 27 (28.42) | 24.3611 |
| 2020's | 3 (3.16) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Dornberger, K; Gebhardt, P; Gollmick, FA; Görls, H; Gräfe, U; Härtl, A; Hertweck, C; Schlegel, B | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bianchi, M; Ghezzi, P; Gianera, L; Landolfo, S; Salmona, M | 1 |
| Abbott, V; Deloria, LB; Mannering, GJ | 1 |
| Lewis, DC; Shibamoto, T | 1 |
| Blake, DR; Green, ID; Howard, RJ; Pall, H; Williams, A | 1 |
| Grichting, G; Jornot, L; Junod, AF | 1 |
| Clark, EP; Stossel, TP; Weitberg, AB; Weitzman, SA | 1 |
| Ghezzi, P; Villa, P | 1 |
| Bowers, JL; Clouse, ME; Cook, CU; Neymark, E | 1 |
| Delgado, R; Demitri, MT; Echtenacher, B; Faggioni, R; Gatti, S; Ghezzi, P; Gnocchi, P; Heremans, H | 1 |
| Harada, T; Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Razandi, M; Sugimoto, T; Terano, A | 1 |
| Bando, T; Hirata, T; Kosaka, S; Liu, CJ; Wada, H | 1 |
| Fukuse, T; Hirata, T; Hitomi, S; Inui, K; Kosaka, S; Liu, CJ; Ueda, M; Wada, H; Yokomise, H | 1 |
| Hinze, H; Lenz, AG; Maier, KL; Meyer, B | 1 |
| Berry, L; Jiang, H; Meyrick, B; Mitchell, J | 1 |
| Bowie, A; O'Neill, LA | 1 |
| Bhunia, AK; Chatterjee, S; Han, H; Snowden, A | 1 |
| Baixaulí, J; Cienfuegos, JA; Díez-Caballero, A; Espí, A; Hernández, JL; Nwose, E; Pardo, F; Regueira, FM; Rotellar, F; Sierra, A | 1 |
| Azzimonti, B; Bernelli-Zazzera, A; Cairo, G; Minotti, G; Recalcati, S; Tacchini, L | 1 |
| Ariceta, J; Balén, E; Ferrer, JV; Gomis, T; Guerrero, D; Larrea, MM; Lera, JM | 1 |
| Fujiwara, Y; Kigawa, G; Kitamura, N; Kumada, K; Kuzume, M; Nagasaki, H; Nakano, H; Sasaki, J; Shimura, H; Takeuchi, S; Yamaguchi, M; Yoshida, K | 1 |
| Altindag, ZZ; Fuchs, D; Wachter, H; Wede, I; Widner, B | 1 |
| Brown, LA; Deutch, E; Lu, LN; Matthay, MA; Modelska, K; Pittet, JF | 1 |
| Chavez-Cartaya, R; Jamieson, NV; Marin, J; Pino-Chavez, G; Ramirez, P | 2 |
| Metodiewa, D; Winterbourn, CC | 1 |
| Ariceta, J; Balén, E; Ferrer, JV; Guerrero, D; Herrera, J; Lera, JM | 1 |
| Buhimschi, CS; Buhimschi, IA; Kramer, WB; Thompson, LP; Weiner, CP | 1 |
| Ben-Abraham, R; Karchevski, E; Rudick, V; Weinbroum, AA | 1 |
| Baquer, NZ; Genet, S; Kale, RK | 1 |
| Chida, M; Fujimura, S; Hoshikawa, Y; Noda, M; Ono, S; Song, C; Suzuki, S; Tabata, T; Tanita, T; Voelkel, NF | 1 |
| Böddinghaus, B; Brade, V; Briner, VA; Dorsch, S; Franzen, R; Huwiler, A; Pautz, A; Pfeilschifter, J | 1 |
| Ahlemeyer, B; Becker, A; Klumpp, S; Krieglstein, J; Ravati, A | 1 |
| de Abreu, R; Dekhuijzen, PN; Heunks, LM; Machiels, HA; van der Heijden, HF; Zhu, XP | 1 |
| Baroni, SS; Dusi, S; Gabrielli, A; Luchetti, M; Orlandini, G; Paroncini, P; Sambo, P | 1 |
| Roumen, RM; Vader, HL; Van Den Wall Bake, AW; Wijnen, MH | 1 |
| Enyedy, EJ; Fisher, CU; Kumar, A; Nambiar, MP; Tsokos, GC; Warke, VG | 1 |
| Allegra, L; Bovio, C; Braga, PC; Dal Sasso, M; Fonti, E; Massoni, C | 1 |
| Karatza, MH; Katsaounou, P; Kollintza, A; Roussos, C; Vassilakopoulos, T; Zakynthinos, S | 1 |
| Abdel-Naim, AB; Mohamadin, AM | 1 |
| Anttila, A; Jusufovic, J; Kauppinen, H; Koivusalo, A; Lindahl, H; Rautelin, H; Rintala, R | 1 |
| Lin, MC; Ou, CC; Tsao, SM; Yin, MC | 1 |
| Chan, EL; Murphy, JT | 1 |
| Adiga, I; Nair, RR; Preeta, R; Smitha, G | 1 |
| Chen, YC; Ko, CH; Shen, SC | 1 |
| Alba, G; Alvarez-Maqueda, M; Bedoya, FJ; Chacón, P; El Bekay, R; Martín-Nieto, J; Monteseirín, J; Pintado, E; Sobrino, F; Vega, A | 1 |
| Gao, JC; Hu, S; Li, JY; Liu, Y; Sheng, ZY; Zhang, C | 1 |
| Chavin, K; Lin, A; Orak, J; Sekhon, B; Sekhon, C; Singh, A; Singh, I; Smith, A | 1 |
| Briggs, JP; Hoidal, JR; Honeggar, M; Kohan, DE; Mizel, D; Sanders, K; Schnermann, JB; Yang, T; Zhang, A | 1 |
| Kil, J; Lynch, ED | 1 |
| Giles, GI; Gillespie, GY; Griguer, CE; Kelley, EE; Lancaster, JR; Oliva, CR | 1 |
| Matkovics, A | 1 |
| Assimakopoulos, SF; Chroni, E; Georgiou, C; Karageorgos, N; Konstantinou, D; Patsoukis, N | 1 |
| De Cock, K; De Muynck, M; Rimbaut, S; Van Maele, G; Vanden Bossche, LC; Vanderstraeten, GG; Vertriest, S; Wojtowicz, I | 1 |
| Amaro, S; Ascione, S; De Luca, B; Monda, M; Viggiano, A; Viggiano, E | 1 |
| Assimakopoulos, SF; Georgiou, CD; Maroulis, I; Patsoukis, N; Scopa, CD; Vagenas, K; Vagianos, CE | 1 |
| Chung, JH; Kim, KH; Lee, Y; Moon, YJ; Seo, JE; Shin, MH | 1 |
| Brincat, S; Hilton, R | 1 |
| Hazra, B; Kumar, A; Kumar, B; Mishra, KP; Pandey, BN | 1 |
| Bru, I; De Muynck, M; Decorte, T; Rimbaut, S; Van Maele, G; Vanden Bossche, LC; Vanderstraeten, G; Wojtowicz, I | 1 |
| Chapman, D; Dhalla, NS; Elimban, V; Maddika, S | 1 |
| Bezerra, FS; Machado, MN; Pires, KM; Porto, LC; Valença, SS; Zin, WA | 1 |
| Irwin, MG; Lam, KS; Lei, S; Liu, Y; Ng, KF; Qiao, S; Wang, T; Xia, Z; Xu, A | 1 |
| Álvares-da-Silva, MR; Alvares-Dasilva, MR; Camacho, VR; Cerski, CT; de Fraga, RS; de Oliveira, JR; Fraga, RS; Oliveira, JR | 1 |
| Burg, MB; Ferraris, JD; Zhou, X | 1 |
| Cho, M; Choi, H; Jeon, S; Karna, S; Kim, J; Kim, O; Kim, S; Lim, C; Lim, W | 1 |
| Irwin, MG; Lei, S; Li, H; Liu, Z; Mao, X; Ng, KF; Qiao, S; Vanhoutte, PM; Wang, J; Wang, T; Wong, GT; Xia, Z; Xu, A | 1 |
| Gao, X; Irwin, MG; Liao, XL; Liu, Y; Mao, X; Ng, KF; Ou, JS; Vanhoutte, PM; Wang, T; Xia, Z; Xu, Y | 1 |
| Ferriero, DM; Juul, SE | 1 |
| Aliakbarian, M; Bahreini, A; Ghaffaripour, S; Nikeghbalian, S; Rajabnejad, Y; Rashidi, M; Shafiee, M | 1 |
| Chen, Y; Gao, F; Huang, Z; Li, W; Liao, H; Lu, S; Shi, G; Sun, T; Wang, B; Xu, H; Zhang, Y; Zheng, F; Zhong, S | 1 |
| Erkut, B; Onk, OA | 1 |
| Antonilli, L; Badiani, A; Grassi, MC; Graziani, M; Saso, L; Togna, AR | 1 |
| Andreazza, AC; Berk, M; Dean, O; Kapczinski, F; Magalhães, PV | 1 |
| Cho, JH; Choi, JY; Kim, CD; Kim, YJ; Kim, YL; Oh, EJ; Oh, SH; Park, SH; Ryu, HM | 1 |
| Ishisaka, A; Kanazawa, S; Kato, Y; Kettle, AJ; Kitamoto, N; Miura, Y; Naito, M; Oki, K; Ono, S; Suga, N | 1 |
| Canale, D; de Bragança, AC; de Brito, T; de Jesus, DA; Gois, PH; Magaldi, AJ; Moreau, RLM; Seguro, AC; Shimizu, MHM; Silva, AMG | 1 |
| Barquissau, V; Capel, F; Chauvin, MA; Dardevet, D; Feillet-Coudray, C; Gallinier, A; Morio, B; Rieusset, J | 1 |
| Bogutska, KI; Matvienko, TY; Mishchenko, IV; Motuziuk, OP; Nozdrenko, DN; Prylutskyy, YI; Sklyarov, YP; Zavodovskyi, DA | 1 |
| Ebi, N; Hamada, E; Kinjo, T; Kobayashi, N; Miyagi-Shiohira, C; Nakashima, Y; Noguchi, H; Saitoh, I; Tamaki, Y; Watanabe, M | 1 |
| Cheung, PY; Schmölzer, GM; Solevåg, AL | 1 |
| Chen, J; Chen, M; Huang, H; Li, X; Liu, F; Liu, M; Wang, J; Wu, H | 1 |
| Bandyopadhaya, A; Rahme, LG; Tzika, AA | 1 |
| Aceti, A; Austin, T; Corvaglia, L; Faldella, G; Martini, S | 1 |
| Chen, AD; Chen, Q; Kang, YM; Li, YH; Qiu, Y; Wang, JJ; Ye, C; Zheng, F; Zhu, GQ | 1 |
| Abdulazim, DO; Amin, M; Csongradi, E; ElAzim, IMA; Elhadidy, S; Fayed, A; Hammad, AA; Hammad, H; Salem, MM; Sharaf El Din, UA; Soliman, KM; Zsom, L | 1 |
10 review(s) available for acetylcysteine and allopurinol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Compounds for the prevention and treatment of noise-induced hearing loss.
Topics: Acetylcysteine; Allopurinol; Azoles; Glutathione Peroxidase; Hearing Loss, Noise-Induced; Humans; Isoindoles; Magnesium; Noise, Occupational; Organoselenium Compounds | 2005 |
[Recent changes in concepts of antioxidant treatment].
Topics: Acetylcysteine; Allopurinol; Antioxidants; Apoptosis; Ascorbic Acid; Cardiovascular Diseases; Clinical Trials as Topic; Coenzymes; Flavonoids; Humans; Meta-Analysis as Topic; Neoplasms; Selenium; Ubiquinone; Vitamin A; Vitamin D; Vitamin E; Vitamin K; Vitamins | 2006 |
Prevention of acute kidney injury.
Topics: Acetylcysteine; Acute Kidney Injury; Allopurinol; Aminoglycosides; Amphotericin B; Antifungal Agents; Contrast Media; Dehydration; Dopamine Agonists; Glomerular Filtration Rate; Humans; Hypovolemia; Natriuretic Peptides; Renal Agents; Renal Circulation; Sodium Potassium Chloride Symporter Inhibitors; Theophylline | 2008 |
Pharmacologic neuroprotective strategies in neonatal brain injury.
Topics: Acetylcysteine; Allopurinol; Antioxidants; Ascorbic Acid; Biopterins; Erythropoietin; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Fructose; Humans; Hypoxia-Ischemia, Brain; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Melatonin; Memantine; Neuroprotective Agents; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Topiramate; Vitamin E; Xenon | 2014 |
Cardiovascular and Hepatic Toxicity of Cocaine: Potential Beneficial Effects of Modulators of Oxidative Stress.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiovascular Diseases; Catecholamines; Cattle; Cocaine; Humans; Liver; Male; Mice; Mitochondria; Myocytes, Smooth Muscle; NADPH Oxidases; Nitrogen Oxides; Oxidative Stress; Rats; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Xanthine Oxidase | 2016 |
Antioxidant treatments for schizophrenia.
Topics: Acetylcysteine; Allopurinol; Antioxidants; Antipsychotic Agents; Ascorbic Acid; Dehydroepiandrosterone; Drug Therapy, Combination; Free Radical Scavengers; Ginkgo biloba; Humans; Oxidative Stress; Randomized Controlled Trials as Topic; Schizophrenia; Selegiline; Vitamin E; Vitamins | 2016 |
[MUSCLE FATIGUE: FACTORS OF DEVELOPMENT AND WAYS OF CORRECTION].
Topics: Acetylcysteine; Allopurinol; Antioxidants; Fullerenes; Humans; Low-Level Light Therapy; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Oxidative Stress; Reactive Oxygen Species | 2017 |
Novel interventions to reduce oxidative-stress related brain injury in neonatal asphyxia.
Topics: Acetylcysteine; Allopurinol; Argon; Asphyxia Neonatorum; Cannabinoids; Erythropoietin; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Magnesium Sulfate; Melatonin; Neuroprotective Agents; Oxidative Stress; Pregnancy; Treatment Outcome; Xenon | 2019 |
Free radicals and neonatal encephalopathy: mechanisms of injury, biomarkers, and antioxidant treatment perspectives.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Asphyxia Neonatorum; Biomarkers; Brain Injuries; Clinical Trials as Topic; DNA; Erythropoietin; Free Radicals; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Malondialdehyde; Melatonin; Nitric Oxide; Oxidative Stress; Prostaglandins; Proteins; Uric Acid | 2020 |
6 trial(s) available for acetylcysteine and allopurinol
| Article | Year |
|---|---|
Improvement in early function of the hepatic graft after treatment of the donor with N-acetylcysteine: clinical study.
Topics: Acetylcysteine; Adenosine; Alanine Transaminase; Alkaline Phosphatase; Allopurinol; Aspartate Aminotransferases; Bile; Bilirubin; Glutathione; Graft Rejection; Humans; Insulin; Liver Transplantation; Middle Aged; Organ Preservation; Organ Preservation Solutions; Prothrombin Time; Raffinose; Survival Rate; Tissue Donors | 1997 |
Can renal dysfunction after infra-renal aortic aneurysm repair be modified by multi-antioxidant supplementation?
Topics: Acetylcysteine; Aged; Albuminuria; Allopurinol; Antioxidants; Aortic Aneurysm, Abdominal; Ascorbic Acid; Female; Humans; Kidney Function Tests; Male; Mannitol; Prospective Studies; Renal Insufficiency; Reperfusion Injury; Vitamin E | 2002 |
Antioxidants attenuate the plasma cytokine response to exercise in humans.
Topics: Acetylcysteine; Adult; Allopurinol; Antimetabolites; Antioxidants; Ascorbic Acid; Creatine Kinase; Cytokines; Exercise; Flow Cytometry; Free Radical Scavengers; Humans; Interleukin-1; Male; Monocytes; Reactive Oxygen Species; Vitamin A; Vitamin E | 2003 |
Intraluminal casein model of necrotizing enterocolitis for assessment of mucosal destruction, bacterial translocation, and the effects of allopurinol and N-acetylcysteine.
Topics: Acetylcysteine; Allopurinol; Analysis of Variance; Animals; Animals, Newborn; Bacterial Translocation; Caseins; Disease Models, Animal; Enterocolitis, Necrotizing; Ileum; Intestinal Mucosa; Lymphatic System; Male; Swine | 2002 |
Effects of N-Acetylcysteine Addition to University of Wisconsin Solution on the Rate of Ischemia-Reperfusion Injury in Adult Orthotopic Liver Transplant.
Topics: Acetylcysteine; Adenosine; Allopurinol; Cold Ischemia; Double-Blind Method; Female; Glutathione; Hospital Mortality; Humans; Hypotension; Insulin; Iran; Length of Stay; Liver Transplantation; Male; Middle Aged; Operative Time; Organ Preservation Solutions; Perfusion; Protective Agents; Raffinose; Reperfusion Injury; Risk Factors; Time Factors; Treatment Outcome; Warm Ischemia | 2017 |
Is the combination of linagliptin and allopurinol better prophylaxis against post-contrast acute kidney injury? A multicenter prospective randomized controlled study.
Topics: Acetylcysteine; Acute Kidney Injury; Allopurinol; Chemoprevention; Contrast Media; Diabetic Nephropathies; Drug Therapy, Combination; Humans; Kidney Failure, Chronic; Linagliptin; Prospective Studies; Protective Agents; Renal Insufficiency, Chronic; Saline Solution | 2023 |
79 other study(ies) available for acetylcysteine and allopurinol
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill).
Topics: Anti-Inflammatory Agents; Basidiomycota; Benzopyrans; Chemistry, Pharmaceutical; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Design; Horseradish Peroxidase; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Xanthine Oxidase | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Role of reactive oxygen intermediates in the interferon-mediated depression of hepatic drug metabolism and protective effect of N-acetylcysteine in mice.
Topics: Acetylcysteine; Allopurinol; Animals; Cytochrome P-450 Enzyme Inhibitors; Free Radicals; Interferons; Iron; Liver; Male; Mice; Mice, Inbred Strains; Oxygen; Poly I-C; Xanthine Oxidase | 1985 |
Role of xanthine oxidase in the interferon-mediated depression of the hepatic cytochrome P-450 system in mice.
Topics: Acetylcysteine; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Allylisopropylacetamide; Animals; Azacitidine; Carboxymethylcellulose Sodium; Cytochrome P-450 Enzyme Inhibitors; Dithiothreitol; Ethylmorphine-N-Demethylase; Interferons; Liver; Male; Mice; Phenobarbital; Poly I-C; Polylysine; Tungsten; Tungsten Compounds; Xanthine Dehydrogenase; Xanthine Oxidase | 1988 |
Relative metabolism of quinones to semiquinone radicals in xanthine oxidase system.
Topics: 1-Propanol; Acetylcysteine; Anthraquinones; Benzoquinones; Cytochrome c Group; Ethanol; Naphthoquinones; Oxidation-Reduction; Quinones; Xanthine Oxidase | 1989 |
Allopurinol/N-acetylcysteine for carbon monoxide poisoning.
Topics: Acetylcysteine; Adult; Allopurinol; Carbon Monoxide Poisoning; Drug Therapy, Combination; Humans; Male | 1987 |
Comparative study on the selenium- and N-acetylcysteine-related effects on the toxic action of hyperoxia, paraquat and the enzyme reaction hypoxanthine-xanthine oxidase in cultured endothelial cells.
Topics: Acetylcysteine; Animals; Aorta, Thoracic; DNA; Endothelium, Vascular; In Vitro Techniques; Oxygen; Paraquat; Selenium; Selenomethionine; Swine; Xanthine Oxidase | 1987 |
Effects of antioxidants on oxidant-induced sister chromatid exchange formation.
Topics: Acetylcysteine; Animals; Benzoates; Benzoic Acid; beta Carotene; Carotenoids; Catalase; Cricetinae; Cricetulus; Female; Free Radicals; Glutathione; Humans; Mannitol; Ovary; Oxygen; Phagocytes; Selenious Acid; Selenium; Sister Chromatid Exchange; Superoxide Dismutase; Vitamin E; Xanthine Oxidase | 1985 |
Effect of N-acetyl-L-cysteine on sepsis in mice.
Topics: Acetylcysteine; Allopurinol; Animals; Cecum; Free Radical Scavengers; Free Radicals; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Oxidative Stress; Sepsis; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 1995 |
31P nuclear magnetic resonance spectroscopic evaluation of liver preservation solutions.
Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Antioxidants; Chromans; Glutathione; Insulin; Liver; Magnetic Resonance Spectroscopy; Male; Nucleotides; Organ Preservation; Organ Preservation Solutions; Perfusion; Raffinose; Rats; Rats, Sprague-Dawley; Verapamil | 1994 |
Role of xanthine oxidase and reactive oxygen intermediates in LPS- and TNF-induced pulmonary edema.
Topics: Acetylcysteine; Allopurinol; Animals; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Pulmonary Edema; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 1994 |
Role for mucous glycoprotein in protecting cultured rat gastric mucosal cells against toxic oxygen metabolites.
Topics: Acetylcysteine; Analysis of Variance; Animals; Anti-Ulcer Agents; Cells, Cultured; Diterpenes; Female; Gastric Mucosa; Glutathione; Glycoproteins; Male; Oxygen; Rats; Rats, Sprague-Dawley; Xanthine Oxidase | 1993 |
Effective 30-hour preservation of canine lungs with modified ET-Kyoto solution.
Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Bucladesine; Dogs; Drug Evaluation, Preclinical; Ethanol; Gluconates; Glutathione; Hydroxyethyl Starch Derivatives; Insulin; Lung; Lung Transplantation; Nitroglycerin; Organ Preservation; Organ Preservation Solutions; Phosphates; Propylene Glycol; Propylene Glycols; Raffinose; Random Allocation; Reperfusion; Solutions; Time Factors; Trehalose | 1996 |
New ET-Kyoto solution containing N-acetylcysteine, nitroglycerin, and dibutyryl cyclic AMP provides reliable 30-hour canine lung preservation.
Topics: Acetylcysteine; Adenosine; Allopurinol; Analysis of Variance; Animals; Bucladesine; Dogs; Endothelium, Vascular; Gluconates; Glutathione; Hydroxyethyl Starch Derivatives; Insulin; Ischemia; Lung; Lung Transplantation; Microscopy, Electron, Scanning; Nitroglycerin; Organ Preservation; Organ Preservation Solutions; Oxygen; Phosphates; Raffinose; Time Factors; Trehalose | 1996 |
Metal-catalyzed inactivation of bovine glucose-6-phosphate dehydrogenase--role of thiols.
Topics: Acetylcysteine; Adenosine Diphosphate; Animals; Cattle; Cysteine; Dipeptides; Edetic Acid; Enzyme Activation; Glucosephosphate Dehydrogenase; Glutathione; Hydrogen Peroxide; Hypoxanthine; Iron; Metals; Oxidation-Reduction; Sulfhydryl Compounds; Xanthine Oxidase | 1996 |
Effect of antioxidants on lipopolysaccharide-stimulated induction of mangano superoxide dismutase mRNA in bovine pulmonary artery endothelial cells.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Blotting, Northern; Cattle; Cell Nucleus; Cell Size; Cells, Cultured; Dimethyl Sulfoxide; Endothelium; Gene Expression Regulation; Lipopolysaccharides; Microscopy; Pulmonary Artery; Reactive Oxygen Species; Superoxide Dismutase | 1996 |
Studies into the mechanism of NF kappa B activation by IL1, TNF and H2O2 in primary and transformed endothelial cells.
Topics: Acetylcysteine; Allopurinol; Cell Line, Transformed; Cells, Cultured; Cyclic N-Oxides; Deferoxamine; DNA-Binding Proteins; Endothelium, Vascular; Humans; Hydrogen Peroxide; I-kappa B Proteins; Interleukin-1; Kinetics; NF-kappa B; NF-KappaB Inhibitor alpha; Pyrrolidines; Thiocarbamates; Tumor Necrosis Factor-alpha; Umbilical Veins | 1997 |
Redox-regulated signaling by lactosylceramide in the proliferation of human aortic smooth muscle cells.
Topics: Acetylcysteine; Antigens, CD; Antioxidants; Buthionine Sulfoximine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Enzyme Inhibitors; Glutathione; Guanosine Triphosphate; Humans; Lactosylceramides; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-fos; Signal Transduction; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1997 |
Effect of reactive oxygen species on iron regulatory protein activity.
Topics: Acetylcysteine; Animals; Down-Regulation; Ferritins; Iron; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Ischemia; Liver; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; RNA-Binding Proteins; Wnt2 Protein; Xanthine; Xanthine Oxidase | 1998 |
Allopurinol and N-acetylcysteine avoid 60% of intestinal necrosis in an ischemia-reperfusion experimental model.
Topics: Acetylcysteine; Allopurinol; Animals; Glutathione; Intestine, Small; Ischemia; Lung; Malondialdehyde; Myocardium; Necrosis; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury | 1998 |
N-acetylcysteine and anti-ICAM-1 monoclonal antibody reduce ischemia-reperfusion injury of the steatotic rat liver.
Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Antibodies, Monoclonal; Choline Deficiency; Fatty Liver; Glutathione; Insulin; Intercellular Adhesion Molecule-1; Ischemia; Liver; Male; Methionine; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Reperfusion Injury | 1998 |
Inhibition of xanthine oxidase by pterins.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Edetic Acid; Ferric Compounds; Formazans; Hydrogen-Ion Concentration; Nitroblue Tetrazolium; Oxidation-Reduction; Pterins; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Superoxides; Time Factors; Uric Acid; Xanthine; Xanthine Oxidase | 1998 |
Inhibition of beta-adrenergic-dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock.
Topics: Acetylcysteine; Adrenergic beta-Antagonists; Animals; Body Fluids; Epinephrine; Epithelium; Fluid Therapy; Free Radical Scavengers; Glutathione; Male; Neutrophils; Oxidation-Reduction; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Shock, Hemorrhagic; Xanthine Dehydrogenase; Xanthine Oxidase | 1999 |
Free radical scavengers to prevent reperfusion injury following experimental warm liver ischaemia. Is there a real physiological benefit?
Topics: Acetylcysteine; Allopurinol; Animals; Free Radical Scavengers; Galactose; Ischemia; Liver; Liver Function Tests; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Vitamin E | 1999 |
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide.
Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Hydrogen Peroxide; Oxygen Consumption; Penicillamine; Reactive Oxygen Species; Sulfhydryl Compounds; Superoxides; Xanthine Oxidase | 1999 |
Free radical scavengers to prevent reperfusion injury following warm liver ischemia.
Topics: Acetylcysteine; Allopurinol; Animals; Free Radical Scavengers; Ischemia; Liver; Liver Circulation; Male; Microcirculation; Organ Preservation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Temperature; Time Factors; Vitamin E | 1999 |
Prevention by somatostatine and N-acetylcisteine of multiorgan failure mediated by oxidative stress after intestinal ischemia.
Topics: Acetylcysteine; Adenosine Triphosphate; Allopurinol; Animals; Glutathione; Heart; Intestine, Small; Ischemia; Liver; Lung; Malondialdehyde; Mesenteric Arteries; Multiple Organ Failure; Myocardium; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Somatostatin | 1999 |
Reduction-oxidation (redox) state regulation of matrix metalloproteinase activity in human fetal membranes.
Topics: Acetylcysteine; Cesarean Section; Culture Media, Conditioned; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Extraembryonic Membranes; Female; Free Radical Scavengers; Humans; Image Processing, Computer-Assisted; Lipopolysaccharides; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nitric Oxide Donors; Nitroarginine; Oxidation-Reduction; Penicillamine; Pregnancy; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Xanthine; Xanthine Oxidase | 2000 |
N-acetyl-L-cysteine for preventing lung reperfusion injury after liver ischemia-reperfusion: a possible dual protective mechanism in a dose-response study.
Topics: Acetylcysteine; Animals; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Ischemia; Liver; Liver Circulation; Lung; Lung Diseases; Male; Perfusion; Pulmonary Circulation; Rats; Rats, Wistar; Reperfusion Injury; Respiration; Xanthine Oxidase | 2000 |
Effects of free radicals on cytosolic creatine kinase activities and protection by antioxidant enzymes and sulfhydryl compounds.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Brain; Catalase; Creatine Kinase; Cytosol; Diabetes Mellitus, Experimental; Dithiothreitol; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Free Radicals; Heart; Hydrogen Peroxide; Insulin; Muscle, Skeletal; Myocardium; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Xanthine; Xanthine Oxidase | 2000 |
Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Chronic Disease; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Oxidative Stress; Oxygen; Phosphatidylcholines; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tunica Media; Ventricular Function, Right; Xanthine Oxidase | 2001 |
Superoxide potently induces ceramide formation in glomerular endothelial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cattle; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Hypoxanthine; Kidney Glomerulus; Naphthoquinones; Superoxides; Vitamin K; Xanthine Oxidase | 2001 |
Preconditioning-induced neuroprotection is mediated by reactive oxygen species and activation of the transcription factor nuclear factor-kappaB.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Astrocytes; Cells, Cultured; Cycloheximide; Enzyme Inhibitors; Ferrous Compounds; Hippocampus; Immunoblotting; Immunohistochemistry; Neurons; NF-kappa B; Protein Synthesis Inhibitors; Rats; Rats, Inbred F344; Reactive Oxygen Species; Staurosporine; Superoxide Dismutase; Xanthine; Xanthine Oxidase | 2001 |
Free radicals in hypoxic rat diaphragm contractility: no role for xanthine oxidase.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Adenosine Triphosphate; Allopurinol; Animals; Diaphragm; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Hypoxia; In Vitro Techniques; Indicators and Reagents; Isotonic Contraction; Male; Muscle Fatigue; Rats; Rats, Wistar; Xanthine Oxidase | 2001 |
Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway.
Topics: Acetylcysteine; Allopurinol; alpha-Tocopherol; Biphenyl Compounds; Cell Division; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Fibroblasts; Growth Substances; Humans; Hydrogen Peroxide; Microscopy, Confocal; NADPH Oxidases; Onium Compounds; Oxidative Stress; Phenotype; Phosphoproteins; Protein Transport; Reactive Oxygen Species; Rotenone; Scleroderma, Localized; Scleroderma, Systemic; Skin; Up-Regulation | 2001 |
Oxidative stress is involved in the heat stress-induced downregulation of TCR zeta chain expression and TCR/CD3-mediated [Ca(2+)](i) response in human T-lymphocytes.
Topics: Acetylcysteine; Allopurinol; Calcium; Calcium Signaling; Cell Fractionation; DNA-Binding Proteins; Down-Regulation; Flow Cytometry; Free Radical Scavengers; Hot Temperature; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Membrane Proteins; Muromonab-CD3; Oxidative Stress; Reactive Oxygen Species; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; T-Lymphocytes; Transcription Factors | 2002 |
Human neutrophil oxidative bursts and their in vitro modulation by different N-acetylcysteine concentrations.
Topics: Acetylcysteine; Adult; Candida albicans; Cell-Free System; Dose-Response Relationship, Drug; Escherichia coli; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunity, Cellular; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Phagocytosis; Respiratory Burst; Staphylococcus aureus; Xanthine Oxidase | 2002 |
In vitro activation of dibromoacetonitrile to cyanide: role of xanthine oxidase.
Topics: Acetonitriles; Acetylcysteine; Catalase; Cyanides; Deferoxamine; Disinfection; Dithiothreitol; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione; Hypoxanthine; In Vitro Techniques; Oxidation-Reduction; Superoxide Dismutase; Water Pollutants, Chemical; Xanthine Oxidase | 2003 |
Protective action on human LDL against oxidation and glycation by four organosulfur compounds derived from garlic.
Topics: Acetylcysteine; Allyl Compounds; Amphotericin B; Antioxidants; Chelating Agents; Copper; Cysteine; Disulfides; Edetic Acid; Garlic; Glucose; Humans; Lipoproteins, LDL; Oxidation-Reduction; Sulfides; Sulfur Compounds; Superoxides; Xanthine Oxidase | 2003 |
Reactive oxygen species mediate endotoxin-induced human dermal endothelial NF-kappaB activation.
Topics: Acetylcysteine; Cell Line, Transformed; Cell Nucleus; Electrophoretic Mobility Shift Assay; Endothelium, Vascular; Ferrous Compounds; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen Peroxide; Lipopolysaccharides; Microscopy, Confocal; NF-kappa B; Reactive Oxygen Species; Skin; Xanthine; Xanthine Oxidase | 2003 |
Variation in mitogenic response of cardiac and pulmonary fibroblasts to cerium.
Topics: Acetylcysteine; Animals; Catalase; Cell Division; Cells, Cultured; Cerium; Fibroblasts; Free Radical Scavengers; Free Radicals; Hypoxanthines; Lung; Myocardium; Organ Specificity; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Xanthine Oxidase | 2003 |
Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species.
Topics: Acetylcysteine; Allopurinol; Antioxidants; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Caspase 3; Caspases; Catalase; Cytochromes c; DNA Fragmentation; Flavanones; Flow Cytometry; Genes, bcl-2; Guanine Nucleotide Dissociation Inhibitors; HL-60 Cells; Humans; Hydroxylation; Male; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; rho Guanine Nucleotide Dissociation Inhibitor beta; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Superoxide Dismutase | 2004 |
15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes.
Topics: Acetylcysteine; Allopurinol; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Chromans; Cyclic N-Oxides; Cyclopentanes; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ions; Lymphocytes; Membrane Proteins; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenanthrolines; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Temperature; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Xanthine Oxidase | 2004 |
The role of oxygen-free radical in the apoptosis of enterocytes in scalded rats after delayed resuscitation.
Topics: Acetylcysteine; Allopurinol; Animals; Apoptosis; Burns; DNA Fragmentation; Enterocytes; Glutathione; Ilium; In Situ Nick-End Labeling; Intestinal Mucosa; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Resuscitation; Shock; Xanthine Oxidase | 2004 |
Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantation.
Topics: Acetylcysteine; Adenosine; Allopurinol; Aminoimidazole Carboxamide; Animals; Apoptosis; Creatinine; Disease Models, Animal; Dogs; Glutathione; Graft Survival; Immunohistochemistry; Insulin; Kidney; Kidney Transplantation; Male; Nephrectomy; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organ Preservation; Organ Preservation Solutions; Raffinose; Reperfusion Injury; Ribonucleotides; Transplantation, Autologous; Tumor Necrosis Factor-alpha | 2004 |
Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Cells, Cultured; Cyclic N-Oxides; Cyclooxygenase 2; Cytochromes c; Dinoprostone; Fluoresceins; Genes, Dominant; Hydrazones; Kidney; Kidney Tubules, Collecting; MAP Kinase Signaling System; Membrane Glycoproteins; Mice; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidase 2; NADPH Oxidases; Onium Compounds; Osmosis; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Reactive Oxygen Species; Rotenone; Thenoyltrifluoroacetone; Time Factors; Xanthine; Xanthine Oxidase | 2005 |
Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells.
Topics: Acetylcysteine; Cell Line, Tumor; Cobalt; Free Radicals; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Xanthine Oxidase | 2006 |
Effect of N-acetylcysteine, allopurinol and vitamin E on jaundice-induced brain oxidative stress in rats.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Brain; Cysteine; Disease Models, Animal; Jaundice, Obstructive; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidative Stress; Rats; Sulfhydryl Compounds; Treatment Outcome; Vitamin E | 2006 |
Free radical scavengers are more effective than indomethacin in the prevention of experimentally induced heterotopic ossification.
Topics: Acetylcysteine; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Double-Blind Method; Drug Synergism; Female; Free Radical Scavengers; Hindlimb; Indomethacin; Ossification, Heterotopic; Osteogenesis; Rabbits; Radiography; Random Allocation | 2007 |
Intracerebroventricular injection of oxidant and antioxidant molecules affects long-term potentiation in urethane anaesthetized rats.
Topics: Acetylcysteine; Analysis of Variance; Anesthetics, Intravenous; Animals; Dentate Gyrus; Electric Stimulation; Excitatory Postsynaptic Potentials; Free Radical Scavengers; Hydrogen Peroxide; Hypoxanthine; Injections, Intraventricular; Long-Term Potentiation; Male; Oxidants; Oxidation-Reduction; Perforant Pathway; Rats; Rats, Sprague-Dawley; Urethane; Xanthine Oxidase | 2008 |
Effect of antioxidant treatments on the gut-liver axis oxidative status and function in bile duct-ligated rats.
Topics: Acetylcysteine; Alanine Transaminase; Allopurinol; alpha-Tocopherol; Animals; Bilirubin; Biomarkers; Free Radical Scavengers; Intestines; Jaundice, Obstructive; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar | 2007 |
Reactive oxygen species produced by NADPH oxidase, xanthine oxidase, and mitochondrial electron transport system mediate heat shock-induced MMP-1 and MMP-9 expression.
Topics: Acetylcysteine; Catalase; Cells, Cultured; Electron Transport; Hot Temperature; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Mitochondria; Mitogen-Activated Protein Kinases; NADPH Oxidases; Reactive Oxygen Species; RNA, Messenger; Superoxides; Xanthine Oxidase | 2008 |
Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells.
Topics: Acetylcysteine; Allopurinol; Animals; Antimycin A; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cardiolipins; Cell Line, Tumor; Cyclosporine; Cytochromes c; Female; Free Radical Scavengers; Humans; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Rotenone; Uncoupling Agents; Vitamin K 3 | 2009 |
Free radical scavengers versus methylprednisolone in the prevention of experimentally induced heterotopic ossification.
Topics: Acetylcysteine; Allopurinol; Animals; Disease Models, Animal; Female; Free Radical Scavengers; Glucocorticoids; Hindlimb Suspension; Methylprednisolone; Ossification, Heterotopic; Placebos; Rabbits; Radiography | 2009 |
Role of oxidative stress in ischemia-reperfusion-induced alterations in myofibrillar ATPase activities and gene expression in the heart.
Topics: Acetylcysteine; Animals; Antioxidants; Calcium-Transporting ATPases; Cardiac Myosins; Catalase; Enzyme Inhibitors; Gene Expression Regulation; In Vitro Techniques; Leupeptins; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Myofibrils; Myosin Heavy Chains; Myosin Light Chains; Oxidative Stress; Perfusion; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Ventricular Dysfunction, Left; Ventricular Pressure; Xanthine; Xanthine Oxidase | 2009 |
N-(2-mercaptopropionyl)-glycine but not allopurinol prevented cigarette smoke-induced alveolar enlargement in mouse.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Disease Models, Animal; Emphysema; Glycine; Lung Injury; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Pulmonary Alveoli; Smoking; Sulfhydryl Compounds; Tobacco Smoke Pollution | 2011 |
N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats.
Topics: Acetylcysteine; Adiponectin; Allopurinol; Animals; Antioxidants; Biomarkers; Blood Glucose; Creatine Kinase, MB Form; Diabetes Complications; Dinoprost; Drug Synergism; Gene Expression Regulation; Hemodynamics; Interleukin-6; Isoprostanes; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Signal Transduction; Tumor Necrosis Factor-alpha | 2011 |
Relationship between ischemia/reperfusion injury and the stimulus of fibrogenesis in an experimental model: comparison among different preservation solutions.
Topics: Acetylcysteine; Adenosine; Alanine Transaminase; Allopurinol; Animals; Aspartate Aminotransferases; Biomarkers; Catalase; Disease Models, Animal; Fructosediphosphates; Glutathione; Insulin; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis; Liver Transplantation; Male; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Time Factors; Transforming Growth Factor beta1 | 2011 |
Water restriction increases renal inner medullary manganese superoxide dismutase (MnSOD).
Topics: Acetylcysteine; Animals; Antimycin A; Catalase; Cells, Cultured; Dogs; Female; Kidney; Male; Mice; NADPH Oxidases; Osmolar Concentration; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Urea; Water Deprivation; Xanthine; Xanthine Oxidase | 2012 |
Effect of 635 nm light-emitting diode irradiation on intracellular superoxide anion scavenging independent of the cellular enzymatic antioxidant system.
Topics: Acetylcysteine; Analysis of Variance; Cell Line, Transformed; Cell Survival; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hydrogen Peroxide; Keratinocytes; Light; Lipid Peroxidation; NAD; Oxidative Stress; Reactive Oxygen Species; Spin Trapping; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 2012 |
N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes.
Topics: Acetylcysteine; Adiponectin; Allopurinol; Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Gene Expression Regulation; Humans; Janus Kinases; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Signal Transduction; STAT3 Transcription Factor; Up-Regulation | 2013 |
N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats.
Topics: 2-Methoxyestradiol; Acetylcysteine; Allopurinol; Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dinoprost; Drug Synergism; Echocardiography; Estradiol; Heme Oxygenase (Decyclizing); Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Isoprostanes; Male; Membrane Potential, Mitochondrial; Metalloporphyrins; Myocardial Reperfusion Injury; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Superoxide Dismutase | 2013 |
Effect of N-n-butyl haloperidol iodide on ROS/JNK/Egr-1 signaling in H9c2 cells after hypoxia/reoxygenation.
Topics: Acetylcysteine; Antipyrine; Cell Hypoxia; Cell Line; Early Growth Response Protein 1; Edaravone; Gene Expression Regulation; Haloperidol; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Xanthine Oxidase | 2015 |
Effect of N-acetylcysteine and allopurinol combination to protect spinal cord ischemia/reperfusion injury induced by aortic cross-clamping in rat model.
Topics: Acetylcysteine; Allopurinol; Animals; Aorta, Thoracic; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Ligation; Male; Neuroprotective Agents; Rats; Reperfusion Injury; Spinal Cord Ischemia | 2015 |
Hypoxanthine induces cholesterol accumulation and incites atherosclerosis in apolipoprotein E-deficient mice and cells.
Topics: Acetylcysteine; Allopurinol; Animals; Apolipoproteins E; Atherosclerosis; Cholesterol; Down-Regulation; Hep G2 Cells; Humans; Hydrogen Peroxide; Hypercholesterolemia; Hypoxanthine; Lipogenesis; Male; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Plaque, Atherosclerotic; Up-Regulation | 2016 |
A novel quinone derived from 5-hydroxyindoleacetic acid reacts with protein: Possible participation of oxidation of serotonin and its metabolite in the development of atherosclerosis.
Topics: Acetylcysteine; Aged; Antibodies, Monoclonal; Aorta; Atherosclerosis; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; Microtomy; Peroxidase; Phenylenediamines; Quinones; Serotonin; Xanthine Oxidase | 2016 |
Ecstasy induces reactive oxygen species, kidney water absorption and rhabdomyolysis in normal rats. Effect of N-acetylcysteine and Allopurinol in oxidative stress and muscle fiber damage.
Topics: Acetylcysteine; Allopurinol; Animals; Aquaporin 2; Blotting, Western; Epithelial Sodium Channels; Free Radical Scavengers; Glutathione; Hallucinogens; Kidney; Kidney Tubules, Collecting; Male; Muscle Fibers, Skeletal; N-Methyl-3,4-methylenedioxyamphetamine; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Rhabdomyolysis; Solute Carrier Family 12, Member 1; Thiobarbituric Acid Reactive Substances; Water | 2017 |
Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8.
Topics: Acetylcysteine; Animals; Antioxidants; Biological Transport; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex IV; Female; Gene Expression Regulation; Glucose; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Stress; Phosphorylation; Progeria; Protein Carbonylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Xanthine Oxidase | 2017 |
Comparison Between Modified Extracellular-Type Trehalose-Containing Kyoto Solution and University of Wisconsin Solution in 18-Hour Pancreas Preservation for Islet Transplantation.
Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Blood Glucose; Bucladesine; Diabetes Mellitus, Experimental; Female; Gluconates; Glutathione; Hydroxyethyl Starch Derivatives; Insulin; Islets of Langerhans Transplantation; Mice, Nude; Nitroglycerin; Organ Preservation; Organ Preservation Solutions; Pancreas; Raffinose; Reproducibility of Results; Swine; Transplantation, Heterologous; Trehalose | 2018 |
N-acetylcysteine tiherapeutically protects against pulmonary fibrosis in a mouse model of silicosis.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Crystallization; Disease Models, Animal; Female; Gene Expression Regulation; Glutathione Peroxidase; Interleukin-1beta; Interleukin-4; Interleukin-6; Lung; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; Nitric Oxide Synthase Type II; Oxidative Stress; Pulmonary Fibrosis; Reactive Oxygen Species; Silicon Dioxide; Silicosis; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2019 |
Pseudomonas aeruginosa Quorum Sensing Molecule Alters Skeletal Muscle Protein Homeostasis by Perturbing the Antioxidant Defense System.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Male; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; NADP; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Reactive Oxygen Species; Transcription Factors; Uncoupling Protein 3; Xanthine Oxidase | 2019 |
Angiotensin Type 1 Receptors and Superoxide Anion Production in Hypothalamic Paraventricular Nucleus Contribute to Capsaicin-Induced Excitatory Renal Reflex and Sympathetic Activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Acetylcysteine; Allopurinol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Capsaicin; Captopril; Ditiocarb; Kidney; Losartan; Male; NADPH Oxidases; Onium Compounds; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Superoxides | 2020 |