acetylcysteine and aflatoxin b1

acetylcysteine has been researched along with aflatoxin b1 in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's4 (26.67)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Hayes, MA; Murray, CA; Rushmore, TH1
Judah, DJ; Moss, EJ; Neal, GE1
Lotlikar, PD; Raj, HG1
Brockman, HE; De Flora, S; Jackson, MA; Stack, HF; Waters, MD1
Arthur, JR; Ellis, EM; Hayes, JD; Judah, DJ; Manson, MM; McLeod, R; Neal, GE1
Groopman, JD; Musser, SM; Scholl, PF1
Egner, PA; Groopman, JD; He, X; Helzlsouer, KJ; Jacobson, LP; Kensler, TW; Kuang, SY; Muñoz, A; Qian, GS; Shen, X; Wang, JB; Wang, JS; Zarba, A; Zhang, BC; Zhu, YR1
Damián, FJ; Jaramillo, F; Llamas, J; Loarca-Piña, MG; Martínez, A; Martínez, C; Ortíz, R; Quezada, T; Reyes, JL; Rodríguez, ML; Valdivia, AG; Yamamoto, L1
Brunel, JM; de Rezende, L; do Amaral, AT; Giardina, T; Morelli, X; Perrier, J; Roche, P; Stocker, P; Vidal, N1
Gan, F; Hou, L; Huang, K; Liu, Z; Qian, G; Zhou, X; Zhou, Y1
Hou, Y; Liang, J; Luo, H; Ma, C; Ren, L; Wang, H; Wang, S; Xu, F; Zhou, Y1
Bahcivan, E; Dik, B; Eser Faki, H; Ozdemir Kutahya, Z; Tras, B; Uney, K1
Bai, H; Chang, X; Dong, W; Feng, C; Ma, Q; Wu, Z; Yang, J1

Reviews

1 review(s) available for acetylcysteine and aflatoxin b1

ArticleYear
Activity profiles of antimutagens: in vitro and in vivo data.
    Mutation research, 1996, Feb-19, Volume: 350, Issue:1

    Topics: Acetylcysteine; Aflatoxin B1; Animals; Antimutagenic Agents; Carcinogens; Chlorophyllides; Cytochrome P-450 Enzyme System; Heterocyclic Compounds; Mutagenicity Tests; Mutagens; Polycyclic Aromatic Hydrocarbons; Vitamin A

1996

Trials

1 trial(s) available for acetylcysteine and aflatoxin b1

ArticleYear
Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China.
    Journal of the National Cancer Institute, 1999, Feb-17, Volume: 91, Issue:4

    Topics: Acetylcysteine; Aflatoxin B1; Anticarcinogenic Agents; Carcinogens; China; Cytochrome P-450 CYP1A2; Double-Blind Method; Drug Administration Schedule; Feasibility Studies; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Liver Neoplasms; Pyrazines; Reproducibility of Results; Thiones; Thiophenes; Treatment Outcome

1999

Other Studies

13 other study(ies) available for acetylcysteine and aflatoxin b1

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Influences of glutathione status on different cytocidal responses of monolayer rat hepatocytes exposed to aflatoxin B1 or acetaminophen.
    Toxicology and applied pharmacology, 1986, Volume: 85, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Aflatoxin B1; Aflatoxins; Animals; Carmustine; Cells, Cultured; Drug Interactions; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Inbred F344

1986
The mercapturic acid pathway metabolites of a glutathione conjugate of aflatoxin B1.
    Chemico-biological interactions, 1985, Volume: 55, Issue:1-2

    Topics: Acetylcysteine; Aflatoxin B1; Aflatoxins; Animals; Chromatography, High Pressure Liquid; Cysteine; Dipeptidases; Dipeptides; Glutathione; Kidney; Male; Rats; Rats, Inbred F344; Swine

1985
Urinary excretion of thiol conjugates of aflatoxin B1 in rats and hamsters.
    Cancer letters, 1984, Volume: 22, Issue:2

    Topics: Acetylcysteine; Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Chromatography, High Pressure Liquid; Cricetinae; Dipeptides; Glutathione; Male; Mesocricetus; Rats; Sulfhydryl Compounds

1984
Protection conferred by selenium deficiency against aflatoxin B1 in the rat is associated with the hepatic expression of an aldo-keto reductase and a glutathione S-transferase subunit that metabolize the mycotoxin.
    Cancer research, 1997, Oct-01, Volume: 57, Issue:19

    Topics: Acetylcysteine; Aflatoxin B1; Aldehyde Reductase; Animals; Antioxidants; Cytosol; DNA Adducts; DNA Damage; Glutathione Transferase; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Oxidative Stress; Rats; Rats, Inbred F344; RNA, Messenger; Selenium

1997
Synthesis and characterization of aflatoxin B1 mercapturic acids and their identification in rat urine.
    Chemical research in toxicology, 1997, Volume: 10, Issue:10

    Topics: Acetylcysteine; Aflatoxin B1; Animals; Biomarkers; Carcinogens; Circular Dichroism; Male; Mass Spectrometry; Rats; Rats, Inbred F344; Sensitivity and Specificity; Stereoisomerism

1997
Efficacy of N-acetylcysteine to reduce the effects of aflatoxin B1 intoxication in broiler chickens.
    Poultry science, 2001, Volume: 80, Issue:6

    Topics: Acetylcysteine; Aflatoxin B1; Alanine Transaminase; Animal Feed; Animals; Aspartate Aminotransferases; Blood Proteins; Body Weight; Chemical and Drug Induced Liver Injury; Chickens; Free Radical Scavengers; Glutathione; Glutathione Transferase; Kidney; Kidney Diseases; Liver; Liver Diseases; Male; Poultry Diseases; Random Allocation; Treatment Outcome

2001
Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides.
    Biochimie, 2012, Volume: 94, Issue:8

    Topics: Acetylation; Acetylcysteine; Aflatoxin B1; Amidohydrolases; Animals; Benzopyrans; Catalysis; Epoxy Compounds; Humans; Inactivation, Metabolic; Kidney; Protein Conformation; Structure-Activity Relationship; Substrate Specificity; Swine

2012
Combination of Selenomethionine and N-Acetylcysteine Alleviates the Joint Toxicities of Aflatoxin B1 and Ochratoxin A by ERK MAPK Signal Pathway in Porcine Alveolar Macrophages.
    Journal of agricultural and food chemistry, 2018, Jun-13, Volume: 66, Issue:23

    Topics: Acetylcysteine; Aflatoxin B1; Animals; Cell Line; Drug Interactions; Immunotoxins; Macrophages, Alveolar; MAP Kinase Signaling System; Ochratoxins; Selenomethionine; Swine

2018
Aflatoxin B1 induces microglia cells apoptosis mediated by oxidative stress through NF-κB signaling pathway in mice spinal cords.
    Environmental toxicology and pharmacology, 2022, Volume: 90

    Topics: Acetylcysteine; Aflatoxin B1; Animals; Apoptosis; Cell Cycle Checkpoints; Cells, Cultured; Male; Mice; Microglia; NF-kappa B; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Spinal Cord

2022
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats.
    Polish journal of veterinary sciences, 2022, Volume: 25, Issue:3

    Topics: Acetylcysteine; Aflatoxin B1; Animals; Dexamethasone; Male; Matrix Metalloproteinase 9; Minocycline; Rats; Rats, Wistar; Reducing Agents; Ubiquinone; Vitamin E

2022
Aflatoxin B1-induced early developmental hepatotoxicity in larvae zebrafish.
    Chemosphere, 2023, Volume: 340

    Topics: Acetylcysteine; Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Larva; Zebrafish

2023