acetylcysteine and acetaldehyde

acetylcysteine has been researched along with acetaldehyde in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's2 (12.50)18.2507
2000's3 (18.75)29.6817
2010's5 (31.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Cederbaum, AI; Rubin, E1
Gonzales, LJ; Parker, CM; Smith, GG; Sprince, H1
Cozzolino, P; Daino, L; Feo, F; Frassetto, S; Garcea, R; Pascale, R; Ruggiu, ME; Vannini, MG1
Sprince, H1
Weber, AL1
Longerich, L; Mian, T; Parai, S; Prabhakaran, V; Vasdev, S1
Bartsch, H; Hergenhahn, M; Weninger, A; Yang, Q1
Lee, YJ; Shukla, SD1
Berkovitch, G; Cutts, SM; Levovich, I; Nudelman, A; Phillips, DR; Rephaeli, A; Swift, LP1
Chen, N; Hanly, L; Koren, G; Rieder, M1
Chen, YT; Hung, DZ; Liao, JW1
Sato, K; Tampo, Y; Tatsunami, R; Yama, K1
Gowda, GA; Koh, DS; Seo, JB1
Arellanes-Robledo, J; Hernández-Nazara, Z; Inagaki, Y; Lakshman, MR; Reyes-Gordillo, K; Rincón-Sánchez, AR; Rojkind, M; Shah, R1
Clemens, DL; Finnigan, RL; Maloney, EP; Scheer, MA; Schneider, KJ; Wells, MA1
Dagur, RS; Donohue, TM; Ganesan, M; Kusum, KK; New-Aaron, M; Osna, NA; Poluektova, LY; Thomes, PG1

Reviews

1 review(s) available for acetylcysteine and acetaldehyde

ArticleYear
Ifosfamide nephrotoxicity in children: a mechanistic base for pharmacological prevention.
    Expert opinion on drug safety, 2009, Volume: 8, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Age Factors; Antineoplastic Agents, Alkylating; Antioxidants; Child; Humans; Ifosfamide; Kidney Diseases; Oxidative Stress; Risk Factors

2009

Other Studies

15 other study(ies) available for acetylcysteine and acetaldehyde

ArticleYear
Mechanism of the protective action of cysteine and penicillamine against acetaldehyde-induced mitochondrial injury.
    Biochemical pharmacology, 1976, Oct-01, Volume: 25, Issue:19

    Topics: Acetaldehyde; Acetylcysteine; Animals; Carbon Dioxide; Cysteine; In Vitro Techniques; Mitochondria, Liver; Oxygen Consumption; Penicillamine; Rats; Structure-Activity Relationship; Time Factors

1976
Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking.
    Agents and actions, 1975, Volume: 5, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Alcoholism; Anesthetics; Animals; Ascorbic Acid; Cysteine; Humans; Lethal Dose 50; Male; Rats; Smoking; Sulfur; Thiamine

1975
Inhibition by ethanol of rat liver plasma membrane (Na+,K+)ATPase: protective effect of S-adenosyl-L-methionine, L-methionine, and N-acetylcysteine.
    Toxicology and applied pharmacology, 1989, Volume: 97, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Animals; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Ethanol; Female; Glutathione; Liver; Methionine; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase

1989
Protective action of sulfur compounds against aldehyde toxicants of cigarette smoke.
    European journal of respiratory diseases. Supplement, 1985, Volume: 139

    Topics: Acetaldehyde; Acetylcysteine; Acrolein; Aldehydes; Animals; Cysteine; Formaldehyde; Lethal Dose 50; Male; Nicotiana; Plants, Toxic; Rats; Respiratory System; Smoke; Sulfur

1985
Formation of the thioester, N,S-diacetylcysteine, from acetaldehyde and N,N'diacetylcystine in aqueous solution with ultraviolet light.
    Journal of molecular evolution, 1981, Volume: 17, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Biological Evolution; Models, Biological; Solutions; Ultraviolet Rays; Water

1981
N-acetyl cysteine attenuates ethanol induced hypertension in rats.
    Artery, 1995, Volume: 21, Issue:6

    Topics: Acetaldehyde; Acetylcysteine; Administration, Oral; Animals; Aorta; Blood Platelets; Blood Pressure; Body Weight; Calcium; Cytosol; Energy Intake; Ethanol; Heart; Hypertension; Kidney; Lipid Peroxidation; Liver; Male; Muscle, Smooth, Vascular; Myocardium; Organ Size; Rats; Rats, Inbred WKY; Renal Circulation; Thiobarbituric Acid Reactive Substances

1995
Cigarette smoke induces direct DNA damage in the human B-lymphoid cell line Raji.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Acetaldehyde; Acetylcysteine; Acrolein; Aldehydes; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; B-Lymphocytes; beta-Naphthoflavone; Biotransformation; Burkitt Lymphoma; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Neoplasm; Formaldehyde; Free Radical Scavengers; Gamma Rays; Humans; Mixed Function Oxygenases; N-Glycosyl Hydrolases; Oxidation-Reduction; Reactive Oxygen Species; Smoke

1999
Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: Acetaldehyde; Acetylcysteine; Animals; Anthracenes; Apoptosis; Blotting, Western; Butadienes; Buthionine Sulfoximine; Caspase 3; Caspases; Cell Nucleus; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ethanol; Genistein; Hepatocytes; Hydrogen Peroxide; Indoles; JNK Mitogen-Activated Protein Kinases; Male; Maleates; Maleimides; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors

2005
Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:3

    Topics: Acetaldehyde; Acetylcysteine; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Formaldehyde; Glutathione; Humans; Membrane Potential, Mitochondrial; Molecular Structure; Prodrugs; Reactive Oxygen Species; Structure-Activity Relationship

2008
Protective effects of fomepizole on 2-chloroethanol toxicity.
    Human & experimental toxicology, 2010, Volume: 29, Issue:6

    Topics: Acetaldehyde; Acetylcysteine; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Antidotes; Antioxidants; Disulfiram; Drug Synergism; Enzyme Inhibitors; Ethylene Chlorohydrin; Fomepizole; Glutathione; Kidney; Lethal Dose 50; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Solvents

2010
Glycolaldehyde induces cytotoxicity and increases glutathione and multidrug-resistance-associated protein levels in Schwann cells.
    Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:7

    Topics: Acetaldehyde; Acetylcysteine; Animals; Cell Survival; Flow Cytometry; Glutathione; Multidrug Resistance-Associated Proteins; Rats; Reactive Oxygen Species; RNA, Small Interfering; Schwann Cells

2013
Apoptotic damage of pancreatic ductal epithelia by alcohol and its rescue by an antioxidant.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Acetaldehyde; Acetylcysteine; Antioxidants; Apoptosis; Caspase 3; Cells, Cultured; Epithelial Cells; Ethanol; Humans; Pancreatic Ducts; Reactive Oxygen Species

2013
Mechanisms of action of acetaldehyde in the up-regulation of the human α2(I) collagen gene in hepatic stellate cells: key roles of Ski, SMAD3, SMAD4, and SMAD7.
    The American journal of pathology, 2014, Volume: 184, Issue:5

    Topics: Acetaldehyde; Acetylcysteine; Animals; Cell Nucleus; Collagen Type II; Cytosol; DNA-Binding Proteins; Down-Regulation; Fibronectins; Genes, Reporter; Hepatic Stellate Cells; Humans; Mice; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; Repressor Proteins; Response Elements; RNA, Messenger; Smad Proteins; Smad3 Protein; Smad4 Protein; Smad7 Protein; Transcription, Genetic; Transforming Growth Factor beta; Up-Regulation

2014
The Involvement of Acetaldehyde in Ethanol-Induced Cell Cycle Impairment.
    Biomolecules, 2016, Mar-31, Volume: 6, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Alcohol Dehydrogenase; Antioxidants; CDC2 Protein Kinase; Cell Line; Chromans; Cyclin-Dependent Kinase Inhibitor p21; Ethanol; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Immunoblotting; M Phase Cell Cycle Checkpoints; Phosphorylation; Reactive Oxygen Species

2016
Alcohol-Induced Lysosomal Damage and Suppression of Lysosome Biogenesis Contribute to Hepatotoxicity in HIV-Exposed Liver Cells.
    Biomolecules, 2021, 10-11, Volume: 11, Issue:10

    Topics: Acetaldehyde; Acetylcysteine; Apoptosis; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cathepsins; Cell Line; Cell Nucleus; Cytosol; Ethanol; HIV Infections; Humans; Liver; Lysosomes; Models, Biological; Organelle Biogenesis; Oxidative Stress; Proteasome Endopeptidase Complex; Transcription Factors

2021