acetylcysteine and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

acetylcysteine has been researched along with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid in 75 studies

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (14.67)18.2507
2000's26 (34.67)29.6817
2010's35 (46.67)24.3611
2020's3 (4.00)2.80

Authors

AuthorsStudies
Dornberger, K; Gebhardt, P; Gollmick, FA; Görls, H; Gräfe, U; Härtl, A; Hertweck, C; Schlegel, B1
Engman, L; Johansson, H; Ott, MK; Phadnis, P; Svartström, O1
Bartolomé, B; Chioua, M; García, AG; Garrido, I; González-Lafuente, L; Ismaili, L; Marco-Contelles, J; Oset-Gasque, MJ; Revuelta, J; Samadi, A; Soriano, E; Tomassolli, I; Valderas, C; Villarroya, M1
Chen, SH; Chen, SY; Chen, Y; Gu, LQ; Huang, ZS; Li, YP; Ou, TM; Tan, JH1
Bartolini, M; Bolognesi, ML; Guidotti, L; Hrabinova, M; Jeřábek, J; Korábečný, J; Kuča, K; Monti, B; Peña-Altamira, LE; Petralla, S; Roberti, M; Sepsova, V; Soukup, O; Uliassi, E1
Bravo-Díaz, C; Losada-Barreiro, S1
Boice, A; He, L; Jiang, Y; Liu, K; Yan, X; Zhang, S1
Benek, O; Benkova, M; Dolezal, R; Hepnarova, V; Hrabinova, M; Janockova, J; Jun, D; Kobrlova, T; Korabecny, J; Kucera, T; Mezeiova, E; Prchal, L; Sobolova, K; Soukup, O1
Chen, H; Tappel, AL3
Bowers, JL; Clouse, ME; Cook, CU; Neymark, E1
Kondo, H; Niki, E; Takahashi, M1
Laffranchi, R; Spinas, GA1
Allen, RG; Cristofalo, VJ; Furth, JJ; Keogh, B; Tresini, M1
Paine, AJ; Rodriguez-Ariza, A1
Fabbri, A; Falzano, L; Fiorentini, C; Malorni, W; Rivabene, R1
Brash, DE; Liu, M; Wikonkal, NM1
Cederbaum, AI; Goasduff, T1
Clothier, RH; Downing, AT; Fry, JR; Garle, MJ; Jassi, KL; Knight, A1
Bang, JH; Choi, KS; Huh, K; Kim, SU; Park, SA1
Alam, J; Das, DK; Ho, YS; Maulik, N; Yoshida, T1
Bauer, I; Bauer, M; Pannen, BH; Paxian, M; Rensing, H; Rickauer, A; Schmeck, J; Schönhofen, S1
Kirima, K; Kyaw, M; Tamaki, T; Tsuchiya, K; Yoshizumi, M1
Kern, TS; Kowluru, RA; Tang, J1
Chang, SY; Chung, JM; Gwag, BJ; Han, PL; Joo, CK; Kang, K; Kim, EY; Moon, HS; Ryu, BR; Yoon, SH1
Gibson, GE; Jeitner, TM; Park, LC; Xu, H; Zhang, H1
Bulger, EM; Garcia, I; Maier, RV1
Alonso-Lebrero, JL; Brieva, A; Domínguez-Jiménez, C; Pivel, JP; Tejedor, R1
Bodo, CC; Cabilla, JP; Duvilanski, BH; Poliandri, AH; Velardez, MO1
Champy, P; Darios, F; Gleye, C; Hirsch, EC; Hocquemiller, R; Höglinger, GU; Jousset, A; Lannuzel, A; Laurens, A; Lombès, A; Medja, F; Michel, PP; Ruberg, M1
Alpert, E; Altman, H; Barash, V; Barnea, D; Gruzman, A; Sasson, S; Totary, H1
Filipov, NM; Lawrence, DA; Seegal, RF1
Agani, FH; Gong, Y1
Borojevic, R; Dal-Pizzol, F; Franceschi, MF; Grivicich, I; Guaragna, RM; Guimarães, EL; Guma, FC; Margis, R; Moreira, JC1
Alili, L; Brenneisen, P; Cat, B; Holtkötter, O; Sies, H; Steinbrenner, H; Stuhlmann, D1
de Groot, H; Klempt, S; Rauen, U1
Agarwal, N; Balasubramanian, D; Chalasani, ML; Gupta, V; Radha, V; Swarup, G1
Campbell, CT; Kha, V; Kleiner, HE; Landry, GM; Prince, M1
Martin, R; Sathishkumar, K; Uppu, RM; Xi, X1
Aschner, M; Au, C; Batoréu, MC; Marreilha dos Santos, AP; Milatovic, D; Santos, D1
Hara, H; Mishima, S; Nakajima, Y; Shimazawa, M; Tsuruma, K1
Baglole, CJ; Ferguson, HE; Garcia-Bates, TM; Kottmann, RM; Olsen, KC; Phipps, RP; Sime, PJ; Strong, ER; Thatcher, TH1
Dymkowska, D; Wojtczak, L1
Chernyak, BV; Domnina, LV; Dugina, VB; Ivanova, OY; Izyumov, DS; Pletjushkina, OY; Popova, EN; Skulachev, VP1
Esser, PR; Lademann, J; Martin, SF; Schempp, CM; Simon-Haarhaus, B; Wölfle, U1
Choi, HJ; Shim, JK; Song, JH1
Dussault, N; Gervais-St-Amour, C; Marcotte, MÈ; Nadeau, PJ; Néron, S; Roy, A1
Auffan, M; Gondikas, AP; Hsu-Kim, H; Liu, J; Marinakos, SM; Meyer, JN; Yang, X1
Chu, HW; Kosmider, B; Mason, RJ; Messier, EM1
Kim, DE; Kim, JS; Kwon, TK; Min, KJ1
Anadón, A; Ares, I; Castellano, V; Martínez, M; Martínez, MA; Martínez-Larrañaga, MR; Ramos, E; Romero, A1
Lee, HG; Yang, JH1
Cho, DH; Hong, J; Jo, YK; Kim, ES; Park, SJ; Shin, JH1
Cindric, M; Cipak, A; Jaganjac, M; Milkovic, L; Stolc, S; Suzana Borovic, S; Waeg, G; Zapletal, E; Zarkovic, N1
Bou-Moughlabey, Y; Echtay, K; El-Rifai, O; Griffiths, D; Hachem, Y; Makki, RF; Nakkash-Chmaisse, H; Usta, J1
Jang, JH; Kwon, TK; Min, KJ; Yang, ES1
Chavan, TS; Gaponenko, V; Gartel, AL; Halasi, M; Hay, N; Wang, M1
Arab, HH; Maghrabi, IA; Omar, HA; Salama, SA; Snapka, RM1
May, JM; Meredith, ME; Qu, ZC1
Carra, E; Castagnola, P; Daga, A; Dono, M; Giaretti, W; Longo, L; Monteghirfo, S; Monticone, M; Stigliani, S; Taherian, R; Zupo, S1
Henao, F; Hortigón-Vinagre, MP1
Bruni, E; Caputo, F; De Nicola, M; Ghibelli, L; González-Flores, D; Pariente, JA; Rodríguez, AB1
Arab, HA; Cheung, K; Hickman, PE; Kadkhodaee, M; Potter, JM; Roberts, MS; Walker, NI1
Aschner, M; Ben, L; Changsheng, Y; Fang, L; Guangwei, X; Hai, Q; Jing, M; Rongzhu, L; Shuhua, W; Wenjun, Z; Yu, B1
Akula, MK; Akyürek, LM; Bergo, MO; Dalin, MG; Ibrahim, MX; Karlsson, C; Le Gal, K; Lindahl, P; Nilsson, J; Sayin, VI; Wiel, C1
Soliman, E; Van Dross, R1
Clemens, DL; Finnigan, RL; Maloney, EP; Scheer, MA; Schneider, KJ; Wells, MA1
Hirota, K; Kusunoki, M; Matsuo, Y; Nishi, K; Okamoto, A; Oku, K; Shingu, K; Sumi, C; Takenaga, K; Tanaka, M1
Bang, HY; Na, HK; Park, SA; Saeidi, S; Surh, YJ1
Chen, Y; Fu, J; Qin, W; Wang, B; Wang, H; Xu, A; Yang, Z; Yu, T1
Chao, MR; Chen, YP; Li, CC; Lin, CP; Liu, KL; Wang, TS1
Coitinho, AS; de Coelho, DM; Deon, M; Guerreiro, GB; Jacques, CE; Jardim, LB; Marchetti, DP; Mescka, CP; Moura, DJ; Poletto, F; Steffens, L; Vargas, CR; Viario, AG1
An, JM; Park, SY; Seo, JT; Seo, SR1
Gryciuk, ME; Maciejczyk, M; Mil, KM; Pawlukianiec, C; Zalewska, A; Żendzian-Piotrowska, M; Ładny, JR1

Reviews

2 review(s) available for acetylcysteine and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

ArticleYear
Free radicals and polyphenols: The redox chemistry of neurodegenerative diseases.
    European journal of medicinal chemistry, 2017, Jun-16, Volume: 133

    Topics: Animals; Free Radicals; Humans; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Polyphenols; Reactive Oxygen Species

2017
Pleiotropic Properties of Valsartan: Do They Result from the Antiglycooxidant Activity? Literature Review and
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Acetylcysteine; Animals; Antioxidants; Captopril; Chloramines; Chromans; Fructose; Glucose; Glycosylation; Humans; Metformin; Oxidation-Reduction; Pyruvaldehyde; Serum Albumin, Bovine; Thioctic Acid; Tosyl Compounds; Valsartan

2021

Other Studies

73 other study(ies) available for acetylcysteine and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

ArticleYear
Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill).
    Bioorganic & medicinal chemistry letters, 2007, May-01, Volume: 17, Issue:9

    Topics: Anti-Inflammatory Agents; Basidiomycota; Benzopyrans; Chemistry, Pharmaceutical; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Design; Horseradish Peroxidase; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Xanthine Oxidase

2007
Exploring a synthetic organoselenium compound for antioxidant pharmacotherapy--toxicity and effects on ROS-production.
    Bioorganic & medicinal chemistry, 2010, Mar-01, Volume: 18, Issue:5

    Topics: Cell Line; Chromans; Free Radical Scavengers; Humans; Macrophages; Neutrophils; Organoselenium Compounds; Reactive Oxygen Species

2010
Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.
    Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2

    Topics: Antioxidants; Brain Ischemia; Cell Line, Tumor; Humans; Hydrogen Bonding; Hydroxyl Radical; Models, Theoretical; Nitrogen Oxides; Reactive Oxygen Species; Thermodynamics

2011
Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2011, Sep-15, Volume: 19, Issue:18

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cell Line, Tumor; Chelating Agents; Curcumin; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Peptide Fragments; Reactive Oxygen Species; Stereoisomerism; Structure-Activity Relationship

2011
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Liver; Molecular Targeted Therapy; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Rats; Resveratrol; Stilbenes; Tacrine

2017
Design and characterization of bivalent compounds as potential neuroprotectants for Alzheimer's disease: Impact of the spacer on biological activity.
    Bioorganic & medicinal chemistry letters, 2018, 04-01, Volume: 28, Issue:6

    Topics: Alzheimer Disease; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Neuroprotective Agents; Piperazine; Piperazines; Structure-Activity Relationship

2018
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile.
    European journal of medicinal chemistry, 2020, Oct-01, Volume: 203

    Topics: Berberine; Blood-Brain Barrier; Cell Line, Tumor; Cholinesterase Inhibitors; Cholinesterases; Drug Design; Humans; Prolyl Oligopeptidases

2020
Vitamin E, selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q, beta-carotene, canthaxanthin, and (+)-catechin protect against oxidative damage to kidney, heart, lung and spleen.
    Free radical research, 1995, Volume: 22, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Canthaxanthin; Carotenoids; Catechin; Chromans; Heart; Liver; Lung; Male; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Selenium; Spleen; Ubiquinone; Vitamin E

1995
Protection of vitamin E, selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q0, coenzyme Q10, beta-carotene, canthaxanthin, and (+)-catechin against oxidative damage to rat blood and tissues in vivo.
    Free radical biology & medicine, 1995, Volume: 18, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Canthaxanthin; Carotenoids; Catechin; Chromans; Coenzymes; Heart; Hemeproteins; Kidney; Liver; Lung; Male; Myocardium; Oxidation-Reduction; Oxidative Stress; Palmitic Acid; Palmitic Acids; Rats; Rats, Sprague-Dawley; Selenium; Spleen; Ubiquinone; Vitamin E; Vitamin E Deficiency

1995
Protection by vitamin E selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q, beta-carotene, canthaxanthin, and (+)-catechin against oxidative damage to liver slices measured by oxidized heme proteins.
    Free radical biology & medicine, 1994, Volume: 16, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Canthaxanthin; Carotenoids; Catechin; Chromans; Dose-Response Relationship, Drug; Hemeproteins; In Vitro Techniques; Male; Oxidants; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Selenium; Ubiquinone; Vitamin D Deficiency; Vitamin E

1994
31P nuclear magnetic resonance spectroscopic evaluation of liver preservation solutions.
    Transplantation, 1994, Jun-15, Volume: 57, Issue:11

    Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Antioxidants; Chromans; Glutathione; Insulin; Liver; Magnetic Resonance Spectroscopy; Male; Nucleotides; Organ Preservation; Organ Preservation Solutions; Perfusion; Raffinose; Rats; Rats, Sprague-Dawley; Verapamil

1994
Peroxynitrite-induced hemolysis of human erythrocytes and its inhibition by antioxidants.
    FEBS letters, 1997, Aug-18, Volume: 413, Issue:2

    Topics: Acetylcysteine; Albumins; Amidines; Antioxidants; Azoles; Catalase; Chromans; Erythrocytes; Glutathione; Hematocrit; Hemolysis; Humans; Isoindoles; Molsidomine; Nitrates; Organoselenium Compounds; Uric Acid; Vitamin E

1997
Interferon-gamma inhibits insulin release and induces cell death in the pancreatic beta-cell line INS-1 independently of nitric oxide production.
    Experimental cell research, 1997, Nov-25, Volume: 237, Issue:1

    Topics: 4-Aminobenzoic Acid; Acetylcysteine; Animals; Antioxidants; Apoptosis; Benzamides; Cells, Cultured; Chromans; Free Radical Scavengers; Humans; Insulin; Insulin Secretion; Interferon-gamma; Islets of Langerhans; Kinetics; Nitric Oxide; omega-N-Methylarginine; para-Aminobenzoates; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Recombinant Proteins

1997
Antioxidants stimulate transcriptional activation of the c-fos gene by multiple pathways in human fetal lung fibroblasts (WI-38).
    Journal of cellular physiology, 1998, Volume: 176, Issue:3

    Topics: Acetylcysteine; Antioxidants; Blotting, Northern; Carcinogens; Chromans; Enzyme Inhibitors; Fetus; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation; Glutathione; Humans; Lung; Masoprocol; Naphthalenes; Protein Kinase C; Proto-Oncogene Proteins c-fos; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation

1998
Rapid induction of NF-kappaB binding during liver cell isolation and culture: inhibition by L-NAME indicates a role for nitric oxide synthase.
    Biochemical and biophysical research communications, 1999, Apr-02, Volume: 257, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Binding, Competitive; Cell Culture Techniques; Cell Separation; Cell Survival; Cells, Cultured; Chromans; Dithiothreitol; Enzyme Inhibitors; Liver; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Oligonucleotides; Protein Binding; Rats; Rats, Sprague-Dawley; Response Elements; Time Factors

1999
N-acetylcysteine protects epithelial cells against the oxidative imbalance due to Clostridium difficile toxins.
    FEBS letters, 1999, Jun-18, Volume: 453, Issue:1-2

    Topics: Acetylcysteine; Antioxidants; Bacterial Proteins; Bacterial Toxins; Chromans; Cytoskeleton; Enterotoxins; Epithelial Cells; Glutathione; Humans; Oxidation-Reduction; Vitamin E

1999
Induction of cyclin-dependent kinase inhibitors and G(1) prolongation by the chemopreventive agent N-acetylcysteine.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antioxidants; Cell Cycle; Cell Line; Chromans; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Fibroblasts; Free Radical Scavengers; G1 Phase; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, p16; Glutathione; Humans; Keratinocytes; Mice; Models, Biological; Neoplasm Proteins; Papilloma; Skin Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1999
NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species.
    Archives of biochemistry and biophysics, 1999, Oct-15, Volume: 370, Issue:2

    Topics: Acetylcysteine; Antioxidants; Cell Line; Chromans; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP2E1; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Stability; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Multienzyme Complexes; NADP; Oxidative Stress; Proteasome Endopeptidase Complex; Reactive Oxygen Species

1999
Stimulation of dichlorofluorescin oxidation by capsaicin and analogues in RAW 264 monocyte/macrophages: lack of involvement of the vanilloid receptor.
    Biochemical pharmacology, 2000, Mar-01, Volume: 59, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Capsaicin; Carcinogens; Chromans; Fluoresceins; Macrophages; Mice; Monocytes; Oxidation-Reduction; Polysorbates; Reactive Oxygen Species; Receptors, Drug; Surface-Active Agents; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin K

2000
Cisplatin-induced apoptotic cell death in mouse hybrid neurons is blocked by antioxidants through suppression of cisplatin-mediated accumulation of p53 but not of Fas/Fas ligand.
    Journal of neurochemistry, 2000, Volume: 75, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cell Nucleus; Cell Survival; Chromans; Cisplatin; DNA Fragmentation; Fas Ligand Protein; fas Receptor; Ganglia, Spinal; Hybrid Cells; Kinetics; Membrane Glycoproteins; Mice; Neuroblastoma; Neurons, Afferent; Tumor Suppressor Protein p53

2000
H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene.
    Circulation, 2001, Mar-27, Volume: 103, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Chromans; Creatine Kinase; Disease Models, Animal; Gene Targeting; Heart; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Heterozygote; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Malondialdehyde; Membrane Proteins; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardium; Reperfusion Injury; Thiourea

2001
Kupffer cells and neutrophils as paracrine regulators of the heme oxygenase-1 gene in hepatocytes after hemorrhagic shock.
    Shock (Augusta, Ga.), 2001, Volume: 15, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Blood Pressure; Cells, Cultured; Chromans; Clodronic Acid; Deferoxamine; Disease Models, Animal; Gadolinium; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; Kupffer Cells; Male; Neutrophils; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Time Factors; Vinblastine

2001
Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:3

    Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Ascorbic Acid; Cells, Cultured; Chelating Agents; Chromans; Ditiocarb; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Onium Compounds; Oxygen Consumption; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vasoconstrictor Agents

2001
Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy.
    Diabetes, 2001, Volume: 50, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Chromans; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet; Dietary Supplements; Galactosemias; Male; Pericytes; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases; Selenium; Vitamin E

2001
Attenuation of Zn2+ neurotoxicity by aspirin: role of N-type Ca2+ channel and the carboxyl acid group.
    Neurobiology of disease, 2001, Volume: 8, Issue:5

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Aspirin; Benzoates; Calcium; Calcium Channels, N-Type; Cerebral Cortex; Chromans; Excitatory Amino Acid Agonists; Ion Channel Gating; Ion Transport; Membrane Potentials; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; omega-Conotoxin GVIA; omega-Conotoxins; Staurosporine; Structure-Activity Relationship; Zinc

2001
Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme.
    Biochimica et biophysica acta, 2002, Mar-16, Volume: 1586, Issue:2

    Topics: Acetylcysteine; Antioxidants; Bombesin; Calcium; Cell Line; Chromans; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Humans; Hydrogen Peroxide; Ketoglutarate Dehydrogenase Complex; Mitochondrial Proteins; Oxidative Stress; Reactive Oxygen Species; Time Factors

2002
Intracellular antioxidant activity is necessary to modulate the macrophage response to endotoxin.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Coagulation Factors; Butylated Hydroxyanisole; Cells, Cultured; Chromans; Endotoxins; F2-Isoprostanes; Inflammation; Macrophages, Alveolar; Male; Rabbits; Reactive Oxygen Species; Respiratory Distress Syndrome; Signal Transduction; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2002
Photoprotective properties of a hydrophilic extract of the fern Polypodium leucotomos on human skin cells.
    Journal of photochemistry and photobiology. B, Biology, 2003, Volume: 70, Issue:1

    Topics: Acetylcysteine; Ascorbic Acid; Cell Adhesion; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Chromans; Cytoskeleton; Fibroblasts; Humans; Plant Extracts; Polypodium; Protective Agents; Skin; Ultraviolet Rays

2003
Cadmium induces apoptosis in anterior pituitary cells that can be reversed by treatment with antioxidants.
    Toxicology and applied pharmacology, 2003, Jul-01, Volume: 190, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cadmium; Caspases; Cell Survival; Chromans; DNA Fragmentation; Free Radical Scavengers; Hormones; Immunohistochemistry; Male; Oxidative Stress; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Vitamin E

2003
The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism.
    Neuroscience, 2003, Volume: 121, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Benzodiazepines; Cell Survival; Cells, Cultured; Chromans; Deoxyglucose; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Energy Metabolism; Excitatory Amino Acid Antagonists; Female; Furans; Glucose; Herbicides; Hexoses; Insecticides; Intracellular Space; Lactones; Male; Mannose; Mesencephalon; Microtubule-Associated Proteins; Mitochondria; Neurons; Neurotoxins; Plant Extracts; Pregnancy; Rats; Rats, Wistar; Reactive Oxygen Species; Rotenone; Tritium; Tyrosine 3-Monooxygenase

2003
4-Hydroxy tempol-induced impairment of mitochondrial function and augmentation of glucose transport in vascular endothelial and smooth muscle cells.
    Biochemical pharmacology, 2004, May-15, Volume: 67, Issue:10

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Biological Transport; Cattle; Cell Membrane; Chromans; Cyclic N-Oxides; Endothelium, Vascular; Glucose; Glucose Transporter Type 1; Guanidines; Mitochondria; Monosaccharide Transport Proteins; Myocytes, Smooth Muscle; RNA, Messenger; Spin Labels

2004
Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:1

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cells, Cultured; Chromans; Cytokines; Enzyme Inhibitors; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Manganese Poisoning; Mice; Microglia; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pentoxifylline; Phosphodiesterase Inhibitors; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone

2005
Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells.
    American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:5

    Topics: Acetylcysteine; Amino Acids, Dicarboxylic; Cell Hypoxia; Chromans; Deferoxamine; DNA-Binding Proteins; Electron Transport; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mitochondria; Nuclear Proteins; Oligomycins; Proton-Translocating ATPases; Reactive Oxygen Species; Transcription Factors; Tumor Cells, Cultured

2005
Relationship between oxidative stress levels and activation state on a hepatic stellate cell line.
    Liver international : official journal of the International Association for the Study of the Liver, 2006, Volume: 26, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Line; Cell Proliferation; Chromans; Cytokines; Liver; Liver Cirrhosis; Mice; Oxidative Stress; Phenotype; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vitamin E

2006
Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species.
    Journal of cell science, 2006, Jul-01, Volume: 119, Issue:Pt 13

    Topics: Acetylcysteine; Antioxidants; Cell Differentiation; Cells, Cultured; Chromans; Disease Progression; Fibroblasts; Humans; Lipid Peroxidation; Models, Biological; Muscle Fibers, Skeletal; Neoplasm Invasiveness; Protein Kinase C; Reactive Oxygen Species; Skin; Smad Proteins; Sodium Selenite; Transforming Growth Factor beta; Transforming Growth Factor beta1

2006
Histidine-induced injury to cultured liver cells, effects of histidine derivatives and of iron chelators.
    Cellular and molecular life sciences : CMLS, 2007, Volume: 64, Issue:2

    Topics: Acetylcysteine; Animals; Butylated Hydroxytoluene; Cell Survival; Cells, Cultured; Chromans; Deferoxamine; Hepatocytes; Histidine; Iron Chelating Agents; Lipid Peroxidation; Male; Molecular Structure; Organ Preservation Solutions; Rats; Rats, Wistar

2007
A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Blotting, Western; Cell Culture Techniques; Cell Cycle Proteins; Cell Survival; Chlorocebus aethiops; Chromans; COS Cells; Fluorescent Antibody Technique, Indirect; Glaucoma; HeLa Cells; Humans; Membrane Transport Proteins; Mutation; Oxidative Stress; Plasmids; Rats; Reactive Oxygen Species; Retinal Ganglion Cells; Transcription Factor TFIIIA; Transfection; Tumor Necrosis Factor-alpha

2007
Pro-apoptotic effects of 1'-acetoxychavicol acetate in human breast carcinoma cells.
    Toxicology letters, 2007, Sep-28, Volume: 173, Issue:3

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Ascorbic Acid; Benzyl Alcohols; Breast Neoplasms; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromans; Dose-Response Relationship, Drug; Enzyme Induction; Female; Humans; Terpenes; Time Factors

2007
Cholesterol secoaldehyde, an ozonation product of cholesterol, induces amyloid aggregation and apoptosis in murine GT1-7 hypothalamic neurons.
    Journal of Alzheimer's disease : JAD, 2007, Volume: 11, Issue:3

    Topics: Acetylcysteine; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Cell Aggregation; Cholestanones; Cholesterol; Cholesterol, HDL; Chromans; DNA Fragmentation; Free Radical Scavengers; Hypothalamus; Lipid Peroxidation; Mice; Myoblasts, Cardiac; Neurons; Ozone; Reactive Oxygen Species; Secosteroids; Trinucleotide Repeat Expansion

2007
Antioxidants prevent the cytotoxicity of manganese in RBE4 cells.
    Brain research, 2008, Oct-21, Volume: 1236

    Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Cell Line, Transformed; Cell Survival; Chlorides; Chromans; Dose-Response Relationship, Drug; Endothelial Cells; Glutathione; L-Lactate Dehydrogenase; Manganese Compounds; Rats; Sulfates; Tetrazolium Salts; Thiazoles

2008
Comparison of bee products based on assays of antioxidant capacities.
    BMC complementary and alternative medicine, 2009, Feb-26, Volume: 9

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Bees; Caffeic Acids; Chromans; Cinnamates; Coumaric Acids; Fatty Acids; Fatty Acids, Monounsaturated; Free Radical Scavengers; Phenylpropionates; Plant Extracts; Pollen; Propolis; Quinic Acid; Trichothecenes

2009
Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:5

    Topics: Acetylcysteine; Cell Differentiation; Cell Nucleus; Chromans; Dose-Response Relationship, Drug; Enzyme Induction; Fibroblasts; Glutathione; Heme Oxygenase-1; Humans; Ligands; Lung; NF-E2-Related Factor 2; Oleanolic Acid; PPAR gamma; Prostaglandin D2; Protein Transport; Rosiglitazone; Thiazolidinediones; Transcription Factor AP-1; Up-Regulation

2009
Arachidonic acid-induced apoptosis in rat hepatoma AS-30D cells is mediated by reactive oxygen species.
    Acta biochimica Polonica, 2009, Volume: 56, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Arachidonic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Cyclic N-Oxides; Epoxy Compounds; Liver Neoplasms; Rats; Reactive Oxygen Species; Spin Labels

2009
Scavenging of reactive oxygen species in mitochondria induces myofibroblast differentiation.
    Antioxidants & redox signaling, 2010, Nov-01, Volume: 13, Issue:9

    Topics: Acetylcysteine; Actins; Antioxidants; Cell Differentiation; Chromans; Fibroblasts; Fibronectins; Humans; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinase 9; Mitochondria; Muscle, Smooth; Myofibroblasts; Phosphorylation; Plastoquinone; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta

2010
UVB-induced DNA damage, generation of reactive oxygen species, and inflammation are effectively attenuated by the flavonoid luteolin in vitro and in vivo.
    Free radical biology & medicine, 2011, May-01, Volume: 50, Issue:9

    Topics: Acetylcysteine; Antioxidants; Cell Line; Chromans; Cyclooxygenase 2; Cytoprotection; Dinoprostone; DNA Damage; Erythema; Extracellular Signal-Regulated MAP Kinases; Fluoresceins; Gene Expression; Humans; Inflammation; Inhibitory Concentration 50; Keratinocytes; Luteolin; Organ Culture Techniques; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Skin Neoplasms; Ultraviolet Rays

2011
Quercetin 7-rhamnoside reduces porcine epidemic diarrhea virus replication via independent pathway of viral induced reactive oxygen species.
    Virology journal, 2011, Oct-04, Volume: 8

    Topics: Acetylcysteine; Animals; Antioxidants; Antiviral Agents; Chlorocebus aethiops; Chromans; Coronavirus Infections; Cytopathogenic Effect, Viral; DNA Fragmentation; Flow Cytometry; Porcine epidemic diarrhea virus; Pyrrolidines; Quercetin; Reactive Oxygen Species; Thiocarbamates; Vero Cells; Virus Replication

2011
Modulation of CD40-activated B lymphocytes by N-acetylcysteine involves decreased phosphorylation of STAT3.
    Molecular immunology, 2012, Volume: 49, Issue:4

    Topics: Acetylcysteine; Antioxidants; B-Lymphocytes; CD40 Antigens; CD40 Ligand; Cell Proliferation; Cell Survival; Cells, Cultured; Chromans; Homeostasis; Humans; Immunoglobulins; Lymphocyte Activation; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor

2012
Mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans.
    Environmental science & technology, 2012, Jan-17, Volume: 46, Issue:2

    Topics: Acetylcysteine; Animals; Caenorhabditis elegans; Chelating Agents; Chromans; Gene Deletion; Ions; Metal Nanoparticles; Oxidative Stress; Particle Size; Silver; Surface Properties

2012
Human alveolar epithelial cell injury induced by cigarette smoke.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Apoptosis; Benzimidazoles; Chromans; Epithelial Cells; Humans; In Situ Nick-End Labeling; Lung Diseases; Microscopy, Fluorescence; Necrosis; NF-E2-Related Factor 2; Oxidative Stress; Phenotype; Propidium; Pulmonary Alveoli; Smoking

2011
High-mobility group box-1 protein induces mucin 8 expression through the activation of the JNK and PI3K/Akt signal pathways in human airway epithelial cells.
    Biochemical and biophysical research communications, 2012, May-11, Volume: 421, Issue:3

    Topics: Acetylcysteine; Cell Line; Chromans; Free Radical Scavengers; HMGB1 Protein; Humans; MAP Kinase Kinase 4; Mucins; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Respiratory Mucosa; Signal Transduction

2012
Cytotoxicity induced by deltamethrin and its metabolites in SH-SY5Y cells can be differentially prevented by selected antioxidants.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:6

    Topics: Acetylcysteine; Antioxidants; Benzoates; Cell Line, Tumor; Cell Survival; Chromans; Humans; Insecticides; Lipid Peroxidation; Melatonin; Neutral Red; Nitriles; Nitrites; Pyrethrins

2012
PCB126 induces apoptosis of chondrocytes via ROS-dependent pathways.
    Osteoarthritis and cartilage, 2012, Volume: 20, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Benzoflavones; Cells, Cultured; Chondrocytes; Chromans; Drug Antagonism; Enzyme Inhibitors; Estrogen Antagonists; NF-kappa B; Nitric Oxide; omega-N-Methylarginine; Polychlorinated Biphenyls; Rabbits; Reactive Oxygen Species

2012
Sertindole, a potent antagonist at dopamine D₂ receptors, induces autophagy by increasing reactive oxygen species in SH-SY5Y neuroblastoma cells.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:7

    Topics: Acetylcysteine; Antioxidants; Antipsychotic Agents; Autophagy; Cell Line, Tumor; Chromans; Dopamine D2 Receptor Antagonists; Humans; Imidazoles; Indoles; Neuroblastoma; Reactive Oxygen Species; Receptors, Dopamine D2

2012
Stobadine attenuates impairment of an intestinal barrier model caused by 4-hydroxynonenal.
    Toxicology in vitro : an international journal published in association with BIBRA, 2013, Volume: 27, Issue:1

    Topics: Acetylcysteine; Aldehydes; Antioxidants; Caco-2 Cells; Carbolines; Cell Differentiation; Cell Survival; Chromans; Humans; Intestinal Mucosa; Lipid Peroxidation; Permeability; Reactive Oxygen Species

2013
Fragrance chemicals lyral and lilial decrease viability of HaCat cells' by increasing free radical production and lowering intracellular ATP level: protection by antioxidants.
    Toxicology in vitro : an international journal published in association with BIBRA, 2013, Volume: 27, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphate; Aldehydes; Animals; Antioxidants; Cell Line, Tumor; Cell Survival; Chromans; Cyclohexenes; Electron Transport Chain Complex Proteins; Glutathione; Humans; L-Lactate Dehydrogenase; Mice; Mitochondrial Membranes; NIH 3T3 Cells; Perfume; Reactive Oxygen Species; Thioctic Acid

2013
Inhibitory effect of butein on tumor necrosis factor-α-induced expression of cell adhesion molecules in human lung epithelial cells via inhibition of reactive oxygen species generation, NF-κB activation and Akt phosphorylation.
    International journal of molecular medicine, 2012, Volume: 30, Issue:6

    Topics: Acetylcysteine; Alveolar Epithelial Cells; Anti-Inflammatory Agents; Cell Adhesion; Cell Line; Cell Nucleus; Chalcones; Chromans; Gene Expression; Green Fluorescent Proteins; Humans; Intercellular Adhesion Molecule-1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2012
ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors.
    The Biochemical journal, 2013, Sep-01, Volume: 454, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Catalase; Cell Line, Tumor; Chromans; Cytomegalovirus; Dioxolanes; Forkhead Box Protein M1; Forkhead Transcription Factors; Free Radical Scavengers; Humans; Hydrogen Peroxide; Oxidants; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; Reactive Oxygen Species; Recombinant Proteins; Ubiquitinated Proteins; Viral Proteins

2013
Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells.
    Inflammation, 2014, Volume: 37, Issue:3

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Line; Cell Proliferation; Chromans; Glutathione; Humans; Hypochlorous Acid; Inflammation; Kidney; Lung; Neutrophils; Nicotine; Oxidation-Reduction; Proliferating Cell Nuclear Antigen

2014
Ascorbate reverses high glucose- and RAGE-induced leak of the endothelial permeability barrier.
    Biochemical and biophysical research communications, 2014, Feb-28, Volume: 445, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Benzamides; Cell Line; Cell Membrane Permeability; Cells, Cultured; Chromans; Cyclic N-Oxides; Dithiothreitol; Dose-Response Relationship, Drug; Endothelial Cells; Glucose; Glycation End Products, Advanced; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Mice; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin, Bovine; Spin Labels

2014
NAC, tiron and trolox impair survival of cell cultures containing glioblastoma tumorigenic initiating cells by inhibition of cell cycle progression.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Astrocytes; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Proliferation; Cell Survival; Chromans; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured

2014
Apoptotic cell death in cultured cardiomyocytes following exposure to low concentrations of 4-hydroxy-2-nonenal.
    Cardiovascular toxicology, 2014, Volume: 14, Issue:3

    Topics: Acetylcysteine; Aldehydes; Animals; Animals, Newborn; Antioxidants; Apoptosis; Calcium; Cardiotoxicity; Cells, Cultured; Chromans; Cysteine Proteinase Inhibitors; Cytoskeleton; Flow Cytometry; Lipid Peroxidation; Membrane Potential, Mitochondrial; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Wistar

2014
Nanoceria protects from alterations in oxidative metabolism and calcium overloads induced by TNFα and cycloheximide in U937 cells: pharmacological potential of nanoparticles.
    Molecular and cellular biochemistry, 2014, Volume: 397, Issue:1-2

    Topics: Acetylcysteine; Antifungal Agents; Apoptosis; Calcium; Cerium; Chromans; Cycloheximide; Free Radical Scavengers; Humans; Membrane Potential, Mitochondrial; Nanoparticles; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; U937 Cells

2014
Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2015, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Chromans; Disease Models, Animal; Female; Free Radical Scavengers; Gentisates; L-Lactate Dehydrogenase; Liver; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Superoxides

2015
Differential protection of pre- versus post-treatment with curcumin, Trolox, and N-acetylcysteine against acrylonitrile-induced cytotoxicity in primary rat astrocytes.
    Neurotoxicology, 2015, Volume: 51

    Topics: Acetylcysteine; Acrylonitrile; Animals; Antioxidants; Astrocytes; Cell Survival; Cells, Cultured; Chromans; Curcumin; Cytotoxins; Glutathione; Lipid Peroxidation; Membrane Potential, Mitochondrial; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats; Reactive Oxygen Species

2015
Antioxidants can increase melanoma metastasis in mice.
    Science translational medicine, 2015, Oct-07, Volume: 7, Issue:308

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Tumor; Chromans; Dietary Supplements; Disease Models, Animal; Glutathione; Humans; Male; Melanoma; Mice; Neoplasm Metastasis

2015
Anandamide-induced endoplasmic reticulum stress and apoptosis are mediated by oxidative stress in non-melanoma skin cancer: Receptor-independent endocannabinoid signaling.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:11

    Topics: Acetylcysteine; Animals; Apoptosis; Arachidonic Acids; Cell Line, Tumor; Cell Survival; Chromans; Endocannabinoids; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Humans; Mice; Oxidative Stress; Polyunsaturated Alkamides; Receptors, Cannabinoid; Signal Transduction; Skin Neoplasms

2016
The Involvement of Acetaldehyde in Ethanol-Induced Cell Cycle Impairment.
    Biomolecules, 2016, Mar-31, Volume: 6, Issue:2

    Topics: Acetaldehyde; Acetylcysteine; Alcohol Dehydrogenase; Antioxidants; CDC2 Protein Kinase; Cell Line; Chromans; Cyclin-Dependent Kinase Inhibitor p21; Ethanol; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Immunoblotting; M Phase Cell Cycle Checkpoints; Phosphorylation; Reactive Oxygen Species

2016
The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells.
    BMC anesthesiology, 2016, 10-24, Volume: 16, Issue:1

    Topics: Acetylcysteine; Anesthetics, Local; Antioxidants; Apoptosis; Bupivacaine; Cell Death; Cell Line, Tumor; Cell Survival; Chromans; Dose-Response Relationship, Drug; HeLa Cells; Humans; Lidocaine; Membrane Potential, Mitochondrial; Mepivacaine; Mitochondria; Neuroblastoma; Reactive Oxygen Species; Time Factors

2016
Docosahexaenoic Acid Induces Expression of Heme Oxygenase-1 and NAD(P)H:quinone Oxidoreductase through Activation of Nrf2 in Human Mammary Epithelial Cells.
    Molecules (Basel, Switzerland), 2017, Jun-10, Volume: 22, Issue:6

    Topics: Acetylcysteine; Antioxidants; Chromans; Docosahexaenoic Acids; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Humans; Kelch-Like ECH-Associated Protein 1; Mammary Glands, Human; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Phosphorylation; Protein Kinase C-delta; RNA, Small Interfering

2017
Contradictory effects of mitochondria- and non-mitochondria-targeted antioxidants on hepatocarcinogenesis by altering DNA repair in mice.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Chromans; Diethylnitrosamine; DNA Repair; Liver Neoplasms, Experimental; Male; Mice; Mitochondria; Oligopeptides; Organophosphorus Compounds; Reactive Oxygen Species; Ubiquinone

2018
CYP450-mediated mitochondrial ROS production involved in arecoline N-oxide-induced oxidative damage in liver cell lines.
    Environmental toxicology, 2018, Volume: 33, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Areca; Arecoline; Cell Line; Chromans; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; DNA Damage; Liver; Mitochondria; Mutagenicity Tests; Oxidative Stress; Penicillamine; Rats; Reactive Oxygen Species; Salmonella

2018
Oxidative Imbalance, Nitrative Stress, and Inflammation in C6 Glial Cells Exposed to Hexacosanoic Acid: Protective Effect of N-acetyl-L-cysteine, Trolox, and Rosuvastatin.
    Cellular and molecular neurobiology, 2018, Volume: 38, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Survival; Chromans; Cytoplasmic Vesicles; DNA Damage; Fatty Acids; Inflammation; Interleukin-1beta; Isoprostanes; Neuroglia; Neuroprotective Agents; Nitrates; Nitrites; Nitrosative Stress; Oxidative Stress; Rats; Rosuvastatin Calcium

2018
Y-27632 Induces Neurite Outgrowth by Activating the NOX1-Mediated AKT and PAK1 Phosphorylation Cascades in PC12 Cells.
    International journal of molecular sciences, 2020, Oct-16, Volume: 21, Issue:20

    Topics: Acetylcysteine; Amides; Animals; Chromans; Free Radical Scavengers; NADPH Oxidase 1; Neuronal Outgrowth; Onium Compounds; p21-Activated Kinases; PC12 Cells; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; rac1 GTP-Binding Protein; Rats; Signal Transduction

2020